association dataset threshold value standardized value PRXL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23364 GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.12244 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38054 COLO741 CCLE Cell Line Gene CNV Profiles 1.0 2.23874 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6756 IFFO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01763 GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01748 HS936T CCLE Cell Line Gene Expression Profiles 1.0 1.8807 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26245 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.01989 GTEX-QDVJ-0005-SM-2TC5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.99807 GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04053 POLR2AphosphoS2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKRC20 DepMap CRISPR Gene Dependency 1.0 2.26149 ETV7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.39952 H3K36me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.31575 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.1111 CTNNBL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5164 Perturb_15826_OE_Nrf2_SRP291725 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.84945 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.884093 GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 1.16151 GTEX-S7SE-0008-SM-33HB1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23102 GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.05103 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.832453 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6472 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 2.29844 Aorta Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.04874 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.0175 PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70186 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30345 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6924 ZNF804A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89461 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC25A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13811 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980889 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null caudal group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04842 TAL1 ENCODE Transcription Factor Targets 1.0 null BHLHA15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7848 PF382 CCLE Cell Line Gene Expression Profiles 1.0 1.42477 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.9974 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.33406 heart_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.18794 MARCHF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30146 GTEX-WFG7-0826-SM-3GIKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08516 SK-MEL cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.08 MRPS33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0277 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null PMC9052432-szac008_suppl_supplementary_table_s3.docx-22-MLXIP_MLXIP Rummagene Transcription Factor Associations 2026 1.0 null NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3008 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null outer CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48098 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.943264 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30683 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29394 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0767 D283MED CCLE Cell Line Gene Expression Profiles 1.0 1.75462 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26382 GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 2.84902 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.1202 JURKAT, CLONE E6-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.89479 SEC61A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31933 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null OSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14335 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56399 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890537 GSE217363_4_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.19366 GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R45C-0008-SM-48FF2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23778 MARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03924 CEBPB ENCODE Transcription Factor Targets 1.0 null ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0793 REC1 CCLE Cell Line Gene CNV Profiles -1.0 -2.17058 kidney_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.861332 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.860449 Proliferative diabetic retinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 AURKB_knockdown_92_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.54633 GSE142684_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.33492 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31771 Myopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 salivarygland_6b HPA Tissue Sample Gene Expression Profiles -1.0 -0.890207 Perturb_16895_KI_Htt_SRP250656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.71607 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.993492 SLC25A25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8879 septal organ BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959153 mRNA_MYCN_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2 Rummagene Transcription Factor Associations 2026 1.0 null SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.49227 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.90137 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26382 GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 0.848289 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8214 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32145 MORCPR CCLE Cell Line Gene CNV Profiles 1.0 1.74819 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8351 GTEX-N7MS-0011-R2a-SM-2HML6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.968094 Perturb_15779_KO_Nrl_SRP009096 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06891 GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 1.01569 GTEX-R55G-0326-SM-48FDM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961154 X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.920308 ACTR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02221 Cytoplasmic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01988 Perturb_1060_Mut_Esr1_SRP087718 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.89498 Perturb_5259_KD_Ubn1_SRP323703 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.89056 GTEX-PLZ4-0008-SM-48TE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10813 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3041 CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.971582 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00287 NCIH292 CCLE Cell Line Gene Expression Profiles -1.0 -2.6013 PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857226 H3K36me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4908 LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07236 NUBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81381 U937 CCLE Cell Line Gene CNV Profiles 1.0 1.63911 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.3523 Retinal detachment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 Cone dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.849 Perturb_15827_OE_Nrf2_SRP291724 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.43305 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.0913 A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.46426 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.04496 GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures -1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.983266 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.0139 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21953 irf8_00000000_splenic_cd11bplusgrdash1_hdash2b_gen_background_lof_mouse_gpl6887_gse39228 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.464643 GSE100863,GSE100864_3_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 1.07652 CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11793 Perturb_5279_OE_Mnx1_ERP140947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.9224 Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.6062 PPOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33339 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47048 RPL31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13927 dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.874334 C3A CCLE Cell Line Gene Expression Profiles 1.0 1.50757 TEAD4 ChEA Transcription Factor Targets 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.24759 GTEX-SSA3-0008-SM-47JWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30267 MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.58803 HCoV-EMC2012_24Hour_23631916_GSE45042 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.29285 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.481 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.88779 ATXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05646 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.65494 GTEX-WH7G-0426-SM-3NMBJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01527 GSE114992,GSE114993_8_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null molt4 HPA Cell Line Gene Expression Profiles -1.0 -0.941479 GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 1.00318 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13776 GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.80542 GTEX-XPT6-0126-SM-4B65S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.896371 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6656 GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.824725 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.11312 ubiquitin-dependent protein catabolic process GO Biological Process Annotations 2025 1.0 null GTEX-X8HC-0726-SM-46MWG GTEx Tissue Sample Gene Expression Profiles 1.0 1.00714 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.35458 GSE93674_2_v_0_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.22692 PMC4595011-pgen.1005555.s002.xlsx-MITF_DOWN_in_30kb-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.6952 GTEX-RUSQ-1026-SM-2TF6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.16906 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20457 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08258 BAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66013 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.8117 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2141 GTEX-P78B-2526-SM-3P5ZY GTEx Tissue Sample Gene Expression Profiles 1.0 0.838507 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 2.0106 GSE151612_0_v_8_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9376 GSE219195_1_v_3_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25101 GSE165548_2_v_5_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1361 GSE60217_1_v_8_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null FASN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3023 rectum_8c HPA Tissue Sample Gene Expression Profiles -1.0 -1.1832 GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TCF21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2608 PJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91118 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.925235 GTEX-OOBJ-2626-SM-2I3F6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03977 GSE147876,GSE147877_2_v_10_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF511 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54037 GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32817 GTEX-R53T-0008-SM-48FEW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.89643 GTEX-WCDI-0008-SM-47JYE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07874 ubiquitin-dependent protein catabolic process GO Biological Process Annotations 2023 1.0 null GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20249 M040416 DepMap CRISPR Gene Dependency 1.0 4.17855 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3944 GTEX-RVPU-0008-SM-3NM8B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50453 superior parietal lobule, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.926179 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23689 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-R53T-0926-SM-3GADH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1179 GSE158320,GSE183351_2_v_1_lin28b_human RummaGEO Gene Perturbation Signatures 1.0 null DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08937 Perturb_5057_OE_Mir344_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.4433 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.875 GTEX-WYJK-0005-SM-3NMA1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13886 GTEX-POMQ-1426-SM-3P61D GTEx Tissue Sample Gene Expression Profiles 1.0 1.08315 PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.59882 GATA1 ENCODE Transcription Factor Targets 1.0 null GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.95139 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0705 FES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54732 GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 0.875261 PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72241 VMRCLCD CCLE Cell Line Gene CNV Profiles 1.0 1.74862 PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.65521 Pancreas Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.02691 u266 HPA Cell Line Gene Expression Profiles 1.0 1.09496 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42596 HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0608 ZSWIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21931 GTEX-N7MS-0011-R4a-SM-2HMKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.843698 RAB11FIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11554 SLC2A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00535 GTEX-PWN1-2626-SM-2I3FH GTEx Tissue Sample Gene Expression Profiles 1.0 0.829657 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15452 GTEX-OHPL-2426-SM-48TDN GTEx Tissue Sample Gene Expression Profiles 1.0 0.972403 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63776 CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.919603 Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.175 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35123 STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null GSE147056_4_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15825_OE_Nrf2_SRP291724 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.84945 ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44537 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5016 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58807 SARS-BatSRBD_36Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.52355 496100374_HIP_possible Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.36135 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPVG-0008-SM-4GICH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02026 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19333 GTEX-T6MO-1126-SM-4DM5D GTEx Tissue Sample Gene Expression Profiles 1.0 0.96659 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18804 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10715 CDK6_knockdown_93_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.7965 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25179 GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 2.23592 GTEX-NL3H-0008-SM-4E3HU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13534 Perturb_8952_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.38334 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53821 H3K36me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QS-0326-SM-2I3EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01564 E2A MotifMap Predicted Transcription Factor Targets 1.0 null GSE120413,GSE120447_3_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19628 GTEX-T5JW-1326-SM-4DM5G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03493 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.61622 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5043 GSE147366_1_v_0_med13_human RummaGEO Gene Perturbation Signatures -1.0 null HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04319 GTEX-RVPU-0011-R7A-SM-2XCAB GTEx Tissue Sample Gene Expression Profiles 1.0 1.10546 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.103 Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6707 perifornical nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963683 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.53591 POLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19987 GTEX-OXRO-1226-SM-48TDL GTEx Tissue Sample Gene Expression Profiles 1.0 0.880071 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.64034 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35557 GTEX-TSE9-2626-SM-4DXV2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39428 GTEX-XBED-0526-SM-47JY3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935651 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.860949 NCIH1568 CCLE Cell Line Gene CNV Profiles 1.0 1.44868 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3642 GTEX-WFG8-0626-SM-3GILJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18513 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11472 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.33132 H3K36me3_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Small_Intestine Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.906642 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0158 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.386 GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.92667 496100611_FWM_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16214 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0072 Retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.181 Perturb_13716_KO_BAP1_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.1754 dorsal motor nucleus of the vagus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.843298 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.4183 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.15437 GSE167373_2_v_3_rbfox1_human RummaGEO Gene Perturbation Signatures 1.0 null medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93124 H3K36me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JJN3 DepMap CRISPR Gene Dependency 1.0 5.75268 GSE218060_5_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26382 GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15386 CCDC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99633 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.136 LN464 CCLE Cell Line Gene Expression Profiles 1.0 1.68571 GTEX-WY7C-0526-SM-3NB3D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06049 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08706 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06549 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.12716 GTEX-N7MS-0526-SM-4E3JP GTEx Tissue Sample Gene Expression Profiles 1.0 0.960561 GTEX-WFG8-0726-SM-3GILP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45491 SKMEL3 CCLE Cell Line Gene Expression Profiles 1.0 2.67392 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6658 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1645 ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.34289 digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.24277 GTEX-U3ZH-0326-SM-3DB7A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.897574 GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.988214 GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05809 GTEX-R55E-0008-SM-48FCG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30559 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943348 SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.890245 ABCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4311 FAM76B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23759 inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950934 KML1 DepMap CRISPR Gene Dependency 1.0 2.08359 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.13055 GTEX-NPJ8-1526-SM-2D7VU GTEx Tissue Sample Gene Expression Profiles 1.0 1.33954 GTEX-TMMY-0008-SM-4DXU3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.890053 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61503 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.1695 ESCRT I complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 1.08365 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4262 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5808 H3K36me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25136 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.2796 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.42128 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.972376 nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02872 SNRNP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24238 TFAP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27486 brain GTEx Tissue Gene Expression Profiles 1.0 1.30261 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.4121 PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32 DEOC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.67554 COV504 CCLE Cell Line Gene CNV Profiles -1.0 -1.638 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.962235 RPL26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23818 FAM78A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0799 NCIH3255 CCLE Cell Line Gene Expression Profiles -1.0 -1.90536 ESCRT complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8056 GTEX-T2IS-2026-SM-4DM6W GTEx Tissue Sample Gene Expression Profiles 1.0 1.40667 GSE186005_1_v_2_klf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE171177,GSE171181_1_v_0_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null GSE130081,GSE130082_0_v_10_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K36me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13503 GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.837549 GTEX-RTLS-2426-SM-46MUO GTEx Tissue Sample Gene Expression Profiles 1.0 1.43555 PSS008 DepMap CRISPR Gene Dependency 1.0 9.12778 SARS-CoV_36Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.29263 TUBA1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.044 H3K36me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24952 SEMA4G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18914 COLO849 CCLE Cell Line Gene Expression Profiles 1.0 1.3543 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5417 CERCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04269 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.61164 GTEX-V955-0726-SM-3GAFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81279 GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 1.38154 CA1 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08875 DCTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.84371 HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.85786 C2orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27407 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6729 GSE156907,GSE160237_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null OXA1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32198 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43638 GTEX-RU1J-0226-SM-2TF5Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.870549 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.1237 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null SGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32608 Perturb_15199_KD_ADA2_SRP266202 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.39194 GSE118939_1_v_0_nras_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.6396 GSE169205_0_v_2_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null FOXD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.25 HARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20263 golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null Sly syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.148 GTEX-PWN1-2426-SM-48TDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.09653 A1207 CCLE Cell Line Gene CNV Profiles 1.0 1.32788 647V CCLE Cell Line Gene CNV Profiles 1.0 1.65433 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985491 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 1.74795 GSE200673,GSE200691_1_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3409 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16646 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83817 KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.99229 GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51425 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.49083 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0364 GSE153836_14_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-TSE9-0008-SM-4DXT8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993611 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.963118 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.919461 pancreas HPA Tissue Gene Expression Profiles -1.0 -1.37367 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6222 GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21385 MOSPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19705 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47048 GSE181517_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35483 brain_3b HPA Tissue Sample Gene Expression Profiles 1.0 0.84804 WAPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83765 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39268 GTEX-U4B1-0008-SM-4DXUW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.994336 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890537 GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998521 PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P4PQ-0326-SM-2HMJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07934 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2931 outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68009 ES-I3 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.08735 GSE171175,GSE171181_1_v_0_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null HCC1806 CCLE Cell Line Gene CNV Profiles -1.0 -2.4575 POU2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72606 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02057 lateral parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.905951 GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02127 GTEX-XMD3-2326-SM-4AT5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.865843 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95767 GTEX-OXRL-0008-SM-3NB29 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00692 GTEX-QMR6-0008-SM-447AV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873414 GTEX-RU72-0011-R2A-SM-2TF6O GTEx Tissue Sample Gene Expression Profiles 1.0 0.970248 PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-latefoetal_NRL Rummagene Transcription Factor Associations 2026 1.0 null GSE182680,GSE182683_5_v_13_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-UPK5-0326-SM-3GAF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32515 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9247 lateral hypothalamic area, anterior region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.848054 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1616 Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4681 A704 CCLE Cell Line Gene Expression Profiles 1.0 1.54379 FAM43B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07055 GTEX-XOTO-3026-SM-4B65M GTEx Tissue Sample Gene Expression Profiles 1.0 1.25732 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.11755 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9967 K029AX CCLE Cell Line Gene Expression Profiles 1.0 1.9657 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9028 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0998 SCOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16914 GTEX-RVPV-0008-SM-47JYW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15723 GTEX-OHPM-0326-SM-33HCA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.956416 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO Biological Process Annotations 2025 1.0 null TATDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25065 JIMT1 CCLE Cell Line Gene Expression Profiles -1.0 -1.97875 GSE182680,GSE182683_0_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4186 GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles 1.0 0.832665 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845876 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.877069 SP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10998 GTEX-S4P3-0426-SM-4AD56 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917563 GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.17994 GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28425 GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08161 GSE103068_5_v_1_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-1256 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GSE206870,GSE206872_0_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RU72-0008-SM-46MV8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2031 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5183 cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.11926 outer CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835884 GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles 1.0 1.02052 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3029 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0105 UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04408 GSE112763,GSE112767_2_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE213588_8_v_13_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42224 primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.51355 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2822 ZNF644 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46021 LB771HNC DepMap CRISPR Gene Dependency 1.0 4.81629 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835028 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.912713 MZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.856703 GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68547 PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.68784 hela HPA Cell Line Gene Expression Profiles 1.0 1.13784 GTEX-S3XE-0526-SM-4AD4G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.866395 inner CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.896737 GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01363 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.9758 GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60904 NCIH1395 CCLE Cell Line Gene CNV Profiles 1.0 1.85107 GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.86268 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08486 GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.846065 EN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81174 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02124 RAD21 ENCODE Transcription Factor Targets 1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19333 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3136 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.83942 FOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9345 GTEX-WVLH-3026-SM-3MJG9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.873897 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5552 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23725 GSE159967_3_v_0_arid5a_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH322 CCLE Cell Line Gene CNV Profiles 1.0 2.77963 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.1714 CDK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60087 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -2.3804 JHOS2 CCLE Cell Line Gene CNV Profiles -1.0 -1.88971 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08202 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26245 SKMEL28 CCLE Cell Line Gene Expression Profiles 1.0 1.49344 MSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32544 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10715 preweaning lethality, incomplete penetrance IMPC Knockout Mouse Phenotypes 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3515 GTEX-O5YT-0326-SM-32PKA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12239 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 1.4634 GTEX-TKQ2-0008-SM-4DM5L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15496 PLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00114 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15295 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6087 HUO9 DepMap CRISPR Gene Dependency 1.0 7.21541 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.72269 GTEX-S7SF-0008-SM-3NM8T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84125 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11641 GTEX-Q2AH-0726-SM-2I3EA GTEx Tissue Sample Gene Expression Profiles 1.0 0.913864 Perturb_5236_KO_Abhd11_SRP237744 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.89781 Perturb_1310_KO_Cntnap4_SRP387040 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.87745 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55G-0008-SM-48FEX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19459 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.411 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842414 orbital frontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.907651 GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81139 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.829127 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -3.77124 SUPT1 CCLE Cell Line Gene Expression Profiles 1.0 1.50992 H3K36me3_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 1.54934 Blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 GTEX-Q2AI-1526-SM-3GIJ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998108 HL-60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15413 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 0.933181 SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE112761,GSE112767_4_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S7PM-0008-SM-3NM9Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35815 GTEX-WHPG-0826-SM-3NMBF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2004 GSE206226_0_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.65923 OAZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07582 hsa-miR-2392 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-PLZ6-0008-SM-48TD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87156 GTEx Lung 20-29 vs 70-79 GTEx Tissue-Specific Aging Signatures 1.0 5.38883 TE159T CCLE Cell Line Gene Expression Profiles -1.0 -2.05775 GSE160083,GSE160084_2_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -2.39152 H3K36me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3342 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98151 DOHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.913468 WM3211 DepMap CRISPR Gene Dependency 1.0 3.69795 PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-human_gene_ortholog_NRL Rummagene Transcription Factor Associations 2026 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 1.16382 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.850474 Perturb_13717_KO_BAP1_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.58546 TE4 CCLE Cell Line Gene CNV Profiles 1.0 1.37436 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98662 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.78706 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.994294 S117 DepMap CRISPR Gene Dependency 1.0 2.14875 TAL1_erythroblast_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XGQ4-0326-SM-4GIEE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02864 GTEX-X3Y1-2426-SM-3P5Z7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.859317 Perturb_12650_KD_IGFBP5_SRP191422 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.1938 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41581 GTEX-RU1J-0008-SM-46MV9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978871 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26461 blood GTEx Tissue Gene Expression Profiles -1.0 -1.35942 GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 2.0659 GSE139455_7_v_6_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-V955-2026-SM-3GAFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846402 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10922 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15983_KO_Larp7_SRP189392 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.42161 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67093 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.00286 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.07091 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.6919 FANCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61137 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.26857 TINAGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21277 GTEX-P4PP-2026-SM-3P61N GTEx Tissue Sample Gene Expression Profiles 1.0 1.0471 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38694 Perturb_5327_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.33267 TAL1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980621 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43216 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41112 H3K36me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 GSE231648_0_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 1.62919 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84942 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08799 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.976861 HSOS1 DepMap CRISPR Gene Dependency 1.0 2.33316 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 NALM-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.865753 GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17215 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41515 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2327 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4323 NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2173 GSE147876,GSE147877_4_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE128076_2_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null MELJUSO CCLE Cell Line Gene Expression Profiles 1.0 1.59521 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09758 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06585 GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855698 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.32058 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3745 GTEX-U3ZN-0226-SM-3DB8D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961956 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37909 GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.22806 Eye-retinal pigment epithelial cell Tabula Sapiens Gene-Cell Associations 1.0 0.456239 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.97408 CEP120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.65086 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8058 DOV13 CCLE Cell Line Gene CNV Profiles -1.0 -1.62118 UBE2L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24099 inner CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57026 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29001 GTEX-X638-0426-SM-47JY2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27285 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.7449 GSE119978,GSE180930_6_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05824 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null ID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31874 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6709 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3214 GRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01252 SKMEL5 CCLE Cell Line Gene Expression Profiles 1.0 2.04754 GTEX-OIZI-0008-SM-2XCFD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43013 prostate BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.43742 Perturb_13736_OE_MYCL_SRP277794 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.6491 CORL279 CCLE Cell Line Gene CNV Profiles -1.0 -1.56352 BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7776 MON1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31709 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.77415 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0357 T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.881989 PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-earlyfoetal_NRL Rummagene Transcription Factor Associations 2026 1.0 null GSE77108_0_v_7_saha_human RummaGEO Drug Perturbation Signatures -1.0 null CDK19_knockdown_148_GSE32108 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.01988 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3625 IARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0002 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05338 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.8897 GTEX-RWSA-0826-SM-2XCBF GTEx Tissue Sample Gene Expression Profiles 1.0 1.12373 RNF139 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10094 SALE CCLE Cell Line Gene Expression Profiles 1.0 1.4434 GSE122067_3_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SARS-dORF6_36Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.5796 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825382 OLIG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.7187 GAPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18762 GSE207122_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.977121 mRNA_MYBL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13477 Perturb_4638_KO_Nanog_SRP125837 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.1199 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41047 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986508 PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27284 GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46222 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830046 GSE114992,GSE114993_8_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0026 GTEX-V1D1-0926-SM-4JBHQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.08742 OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.64797 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.62488 Perturb_4849_KD_ZEB2_SRP059197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.02785 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RUSQ-0526-SM-2TF72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898693 GSE164508_1_v_0_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.965129 mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null neuro2a BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 GTEX-XUJ4-0008-SM-4BOQI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12595 Perturb_15744_KO_Cyp4v3_SRP358013 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.66242 Kidney - Medulla GTEx Tissue Gene Expression Profiles 2023 1.0 4.92535 HCC1500 CCLE Cell Line Gene CNV Profiles -1.0 -1.56679 CD8_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.08188 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22699 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890537 GSE218060_7_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98662 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49324 GSE242290_3_v_11_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-S4UY-0008-SM-3NM8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958077 GTEX-T5JW-0008-SM-4DM5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20945 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42929 colonrectum_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.99711 GSE60217_1_v_10_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1161 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6936 GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 0.965902 RMSYM DepMap CRISPR Gene Dependency 1.0 4.01255 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9601 GTEX-NPJ7-0011-R8a-SM-2I3G2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10065 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94014 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.985286 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.927921 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.50437 GSE198982,GSE198986_1_v_2_daunorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE206729_5_v_1_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null HH CCLE Cell Line Gene CNV Profiles -1.0 -2.97917 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11316 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936013 endometrium HPA Tissue Gene Expression Profiles 1.0 0.909695 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.39767 GSE77108_0_v_9_saha_human RummaGEO Drug Perturbation Signatures -1.0 null arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.7043 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.22021 JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24363 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.1083 ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.026121 GSE128076_1_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.970892 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 2.1071 PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.60621 496100586_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.40667 GTEX-WFG7-2226-SM-3GIKP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2203 NCIH1651 CCLE Cell Line Gene CNV Profiles 1.0 2.02141 Perturb_1065_Mut_Esr1_SRP087718 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.89494 GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24313 GSE200320_3_v_2_mfge8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.827208 Retinal pigment epithelium cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.926 GSE226285_3_v_0_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6964 UMA domain InterPro Predicted Protein Domain Annotations 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36621 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.865358 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7646 IGR1 CCLE Cell Line Gene Expression Profiles 1.0 1.8485 GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2399 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.61242 GSE183335,GSE183351_1_v_0_lin28b_human RummaGEO Gene Perturbation Signatures -1.0 null CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49275 GTEX-R55C-0326-SM-3GAF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15561 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.94132 OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07874 PMC8355128-41598_2021_95695_MOESM1_ESM.xlsx-Table_S5-Supplementary_Table_S5_List_of_the_protein_precursors_which_were_found_only_in_CRS_when_comparing_with_HF_and_CKD_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null BICR16 DepMap CRISPR Gene Dependency 1.0 2.51963 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.886249 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0909 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.87055 GTEX-OXRK-0826-SM-2HMK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07667 GTEX-OHPN-0008-SM-4E3HW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835278 GSE169205_0_v_8_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12751 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868524 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8479 Perturb_14494_KO_Igsf11_SRP320670 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.44641 496100641_PCx_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08623 GTEX-WHSB-1626-SM-3LK6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.831678 GTEX-S4Z8-0008-SM-33HAZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17074 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.3545 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939983 HCC56 CCLE Cell Line Gene Expression Profiles -1.0 -1.96873 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1991 GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.98553 WDHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91661 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6398 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.14621 H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4877_OE_BANCR_SRP135857 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.53551 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8784 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985491 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2641 MARK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87978 GLMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58443 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 80.4585 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.891322 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7163 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.52046 Benign prostatic hyperplasia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.986 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.40177 certolizumab pegol_homo sapiens_gpl570_gse33585 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19628 UACC257 CCLE Cell Line Gene Expression Profiles 1.0 2.39792 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38746 COLO829 CCLE Cell Line Gene CNV Profiles -1.0 -1.33323 H3K36me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T2IS-0011-R2A-SM-32QPF GTEx Tissue Sample Gene Expression Profiles 1.0 0.94029 colonrectum_f HPA Tissue Sample Gene Expression Profiles -1.0 -0.934586 G361 CCLE Cell Line Gene Expression Profiles 1.0 1.45082 Perturb_13714_KO_ASXL3_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.38273 LAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56677 GSE211151_1_v_4_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE206870,GSE206872_1_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.271 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19507 GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 0.833681 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4878 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.11163 GTEX-TSE9-2826-SM-4DXTF GTEx Tissue Sample Gene Expression Profiles 1.0 1.23905 Melanoma cell line TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE242290_3_v_2_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22028 H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hel HPA Cell Line Gene Expression Profiles -1.0 -1.32247 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1608 Malignant tumor of pancreas_saliva_GSE14245 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.49708 GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 0.858195 Eye-muller cell Tabula Sapiens Gene-Cell Associations 1.0 1.95291 TAL1_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE213588_10_v_11_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5582 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07416 PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF Rummagene Transcription Factor Associations 2026 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45824 GSE120413,GSE120447_4_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.83082 GTEX-X4EO-0126-SM-3P5YN GTEx Tissue Sample Gene Expression Profiles 1.0 0.906232 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43501 Retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.246 GSE128076_1_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null GSE236003_2_v_3_ubr5_human RummaGEO Gene Perturbation Signatures -1.0 null BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4721 GTEX-WFG8-2426-SM-3GILL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49361 LIG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41982 GTEX-WH7G-0326-SM-3NMBH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26694 GTEX-RTLS-2326-SM-46MUH GTEx Tissue Sample Gene Expression Profiles 1.0 1.22539 GTEX-XOT4-0326-SM-4B66S GTEx Tissue Sample Gene Expression Profiles 1.0 1.16296 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.84957 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.341 MOB3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42491 PITX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7269 Perturb_5325_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.54666 DMS153 CCLE Cell Line Gene CNV Profiles -1.0 -2.12291 Eye degenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.242 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.17919 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84942 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2674 Perturb_5237_KO_Abhd11_SRP237744 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6201 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41656 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8273 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.833 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58798 GSE203362_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE213588_8_v_4_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null cerebellar cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.844029 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05603 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.1926 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79976 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles 1.0 0.84928 GTEX-SNOS-0008-SM-4DM6I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55454 GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.299 Perturb_6087_KD_XRN2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.12524 PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1197 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0687 SNRPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02138 GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE224294_3_v_2_ngly1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U3ZN-1026-SM-4DXTC GTEx Tissue Sample Gene Expression Profiles 1.0 0.958432 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.969299 C84 DepMap CRISPR Gene Dependency 1.0 3.27886 GSE201042_2_v_1_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE112763,GSE112767_4_v_5_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null RPMI8226 DepMap CRISPR Gene Dependency 1.0 3.05172 Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.7703 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70354 septum (resp epith) BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 0.991976 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41329 GTEX-VUSG-1726-SM-4KKZL GTEx Tissue Sample Gene Expression Profiles 1.0 0.919442 CALCOCO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18843 GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.67697 GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18874 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830991 MAP3K11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2975 GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1795 RAB43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87388 SBK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2503 cell part LOCATE Predicted Protein Localization Annotations 1.0 null NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9174 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17232 NCIH1437 CCLE Cell Line Gene CNV Profiles 1.0 1.36155 ACTL6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.08958 GTEX-PWCY-1426-SM-48TCT GTEx Tissue Sample Gene Expression Profiles 1.0 0.859972 GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09382 TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HT1197 CCLE Cell Line Gene CNV Profiles -1.0 -1.68917 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.92989 PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null GSE128076_2_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures 1.0 null SK23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.83305 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5869 TMUB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43287 GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.76228 PLIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52041 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -1.68248 TRMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.424 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2575 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.837463 outer CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92218 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26559 GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09557 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4403 Endosome membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 preweaning lethality, incomplete penetrance MGI Mouse Phenotype Associations 2023 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01473 lateral hypothalamic area, mammillary region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.852174 GSE114258_1_v_0_foxk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00033 GSE114992,GSE114993_4_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6259 GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 2.44135 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 2.06123 GAPVD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25669 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5606 C99 DepMap CRISPR Gene Dependency 1.0 4.65226 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45722 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960714 OVOL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4794 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.44589 GTEX-WFON-0226-SM-3GIKR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93978 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 2.67591 GSE213588_10_v_13_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null ubiquitin binding GO Molecular Function Annotations 2025 1.0 null EFTUD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6831 MCC13 DepMap CRISPR Gene Dependency 1.0 2.92428 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.443 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3249 FAM174C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11275 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.0863 lateral orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.923523 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52919 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844132 PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null RPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85321 GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935814 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.21382 GSE182680,GSE182683_0_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE248858_4_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 3.40687 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.854119 UMUC7 DepMap CRISPR Gene Dependency 1.0 2.75685 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925947 MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98662 GTEX-T6MN-0011-R8A-SM-32QP3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882289 SMN-Sm protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.319 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29336 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.980803 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860996 Perturb_3687_KD_RARRES2_SRP287866 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.95422 GSE242290_1_v_11_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.06423 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9944 GTEX-XOTO-0008-SM-4GICE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06479 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6814 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.6689 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10986 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 1.56833 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1317 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900442 GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45089 GTEX-RWS6-1926-SM-47JXY GTEx Tissue Sample Gene Expression Profiles 1.0 1.12829 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93437 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2269 NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.20116 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911897 EBC1 DepMap CRISPR Gene Dependency 1.0 3.7795 496100634_HIP_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.03633 ovary_6b HPA Tissue Sample Gene Expression Profiles 1.0 1.40493 GSE218960_0_v_1_nrf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K36me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.833861 GSE223893_4_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH2122 CCLE Cell Line Gene CNV Profiles 1.0 1.59993 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42587 SNU1272 CCLE Cell Line Gene CNV Profiles -1.0 -2.03396 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39796 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40673 GTEX-NFK9-0726-SM-2HMJW GTEx Tissue Sample Gene Expression Profiles 1.0 1.24348 GTEX-WFG7-0726-SM-3GIKO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4044 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GSE112763,GSE112767_2_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null PSMB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7255 GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -3.32848 NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -2.18929 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -4.16942 CDC25B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02454 GSE173873_4_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null WM88 CCLE Cell Line Gene Expression Profiles 1.0 1.64082 OVMANA DepMap CRISPR Gene Dependency 1.0 3.16729 PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00816 H3K36me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0381 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8965 inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846176 TCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11827 GTEX-U3ZH-1426-SM-4DXSR GTEx Tissue Sample Gene Expression Profiles 1.0 1.01956 CUX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0536 primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.56295 GSE128730_4_v_5_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12079334-ADVS-12-2501734-s002.pdf-149-ENSG00000180357_ZNF609 Rummagene Transcription Factor Associations 2026 1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null CA1 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42466 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09821 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 2.15632 RBIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55216 GSE147876,GSE147877_2_v_7_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null 496100559_FWM_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01942 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7026 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.96665 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23375 ovary_8a HPA Tissue Sample Gene Expression Profiles 1.0 0.836556 hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20884 MALME3M DepMap CRISPR Gene Dependency 1.0 2.0723 Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.5703 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22304 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.85141 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.86835 ovary HPA Tissue Gene Expression Profiles 1.0 1.0804 RAF1_activemutant_219_GSE42964 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.26578 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37909 Perturb_4562_KD_Setdb1_SRP126769 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.51343 GSE168401_1_v_3_harmine_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6003 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14508 TACC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13712 GSE100217_2_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null UFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4623 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61817 GSE206226_2_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.999633 skeletal muscle HPA Tissue Gene Expression Profiles 1.0 0.868536 MSANTD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18832 PSMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61534 H3K36me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-0326-SM-2I3FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41548 SAP30 ENCODE Transcription Factor Targets 1.0 null TEX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19889 GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 1.07682 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5197 G402 DepMap CRISPR Gene Dependency 1.0 3.67866 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.67139 DBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17458 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.48215 EN1 JASPAR Predicted Transcription Factor Targets 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_1066_KO_Esr1_SRP087718 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.40503 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36621 SIG-M5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.876253 GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03189 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.56381 PMC12606276-41698_2025_1121_MOESM1_ESM.pdf-41-PHF20_PHF20 Rummagene Transcription Factor Associations 2026 1.0 null TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.6541 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.42512 PMC12549544-mmc2.xlsx-AA_D7_VS_D14-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.7132 PLXNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52384 GTEX-N7MT-0011-R2a-SM-2I3GI GTEx Tissue Sample Gene Expression Profiles 1.0 0.921727 KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.68501 GTEX-SN8G-1526-SM-4DM79 GTEx Tissue Sample Gene Expression Profiles 1.0 0.82837 GTEX-R55E-0011-R9A-SM-2TC6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.13472 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43445 INTS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37184 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K36me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-WHWD-0426-SM-3LK83 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.927947 SW1463 CCLE Cell Line Gene CNV Profiles -1.0 -1.42912 TT1TKB DepMap CRISPR Gene Dependency 1.0 8.46968 GSE224677_2_v_1_dhx9_human RummaGEO Gene Perturbation Signatures 1.0 null medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.861312 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.8065 GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 1.11865 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.905435 CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.881 SREK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93112 CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL3G-0008-SM-4E3JX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41866 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30943 PPIP5K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50307 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null skin_6a HPA Tissue Sample Gene Expression Profiles 1.0 0.94977 placenta_6a HPA Tissue Sample Gene Expression Profiles -1.0 -2.34528 Tongue muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.986 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0044 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03988 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.915564 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 VPS16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04699 inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.23156 GSE127790_5_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZMAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22578 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03765 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18271 GSE147366_1_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.49451 PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93772 GTEX-R55F-0226-SM-48FCI GTEx Tissue Sample Gene Expression Profiles 1.0 1.19852 CENPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72022 Perturb_5343_KO_Taf3_SRP007832 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PECAPJ34CLONEC12 CCLE Cell Line Gene CNV Profiles 1.0 1.43376 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0267 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.304 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32019 CUL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28295 MON DepMap CRISPR Gene Dependency 1.0 2.34939 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.841441 GSE88819_3_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S3XE-0426-SM-3K2AC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46171 CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EIF3E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6001 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47048 496100539_HIP_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.2387 GTEX-XQ8I-1726-SM-4BOQB GTEx Tissue Sample Gene Expression Profiles 1.0 0.88062 TBX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11149 primary auditory cortex (core)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03448 GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.97217 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.66937 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08937 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.990479 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.9258 GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.68239 GTEX-P78B-1926-SM-3P616 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07173 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37833 GSE127790_10_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null PPP1R8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28361 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.406 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.869583 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.73557 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39213 OCIMY7 DepMap CRISPR Gene Dependency 1.0 7.48491 GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.891093 fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.964036 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830991 Melanoma in congenital melanocytic nevus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.315 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.28585 WSB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14459 cone-rod dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.003 PDK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73128 GTEX-RWSA-2026-SM-47JX8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1666 NDUFB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45785 SBDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26399 METTL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61881 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830991 Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.0646 VMRCLCD DepMap CRISPR Gene Dependency 1.0 2.85323 MCMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30993 GTEX-PLZ5-0626-SM-2I5F8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.994618 GTEX-S7SF-1326-SM-4AD4P GTEx Tissue Sample Gene Expression Profiles 1.0 1.10057 GSE101239_4_v_6_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null TTC642 DepMap CRISPR Gene Dependency 1.0 2.38445 GTEX-R55C-0008-SM-48FCF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64333 OTX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0851 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56451 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.04064 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.838465 H3K36me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1795 DAUDI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04953 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.4425 PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null OLIG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8881 YARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63642 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.67023 GTEX-R3RS-0008-SM-48FF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39275 Eye-eye photoreceptor cell Tabula Sapiens Gene-Cell Associations 1.0 15.4022 GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.809 NMB DepMap CRISPR Gene Dependency 1.0 7.99723 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2187 SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -2.10655 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.52034 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0715 KP4 CCLE Cell Line Gene CNV Profiles 1.0 1.83822 GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.95696 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.53963 GTEX-QDT8-0011-R8A-SM-32PKE GTEx Tissue Sample Gene Expression Profiles 1.0 1.28305 OCUM1 CCLE Cell Line Gene CNV Profiles 1.0 1.86142 GTEx Esophagus 20-29 vs 50-59 GTEx Tissue-Specific Aging Signatures 1.0 7.98503 GTEX-P4PP-0326-SM-33HC4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23923 SU-DHL-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.870899 SCC9 CCLE Cell Line Gene CNV Profiles -1.0 -1.34657 GTEX-S341-0008-SM-4AD6D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45834 mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05824 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.19802 ALEXANDERCELLS CCLE Cell Line Gene CNV Profiles 1.0 1.33949 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null URB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19505 mRNA_RXRA_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NEUROD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33466 SLC46A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58285 MEWO CCLE Cell Line Gene Expression Profiles 1.0 1.70538 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33315 FOXP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8448 GTEX-S341-0726-SM-4AD5R GTEx Tissue Sample Gene Expression Profiles 1.0 0.91274 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19182 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79758 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7711 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84639 NUP88 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26714 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8297 HSPB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45703 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0364 MELHO CCLE Cell Line Gene Expression Profiles 1.0 1.82196 HCC1143 CCLE Cell Line Gene CNV Profiles 1.0 1.40224 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50513 Perturb_15806_KO_Cebpg_SRP350242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE214583,GSE214585_1_v_0_steap1_human RummaGEO Gene Perturbation Signatures 1.0 null tail of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.916157 SARS-CoV_72Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.29711 GTEX-T2YK-0008-SM-4DM6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29093 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.219 GTEX-P4QT-0008-SM-48TDZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21572 an3ca HPA Cell Line Gene Expression Profiles 1.0 1.26703 GTEX-N7MT-0726-SM-3TW8S GTEx Tissue Sample Gene Expression Profiles 1.0 1.30525 organelle LOCATE Predicted Protein Localization Annotations 1.0 null amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20715 496100319_HIP_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.08622 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11794 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10612 GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 0.954729 JMSU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.62182 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures -1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1795 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.75627 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.952324 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.41685 H1_BMP4_Derived_Mesendoderm_Cultured_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.12698 GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04011 GTEX-PWCY-0526-SM-2I3ER GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34135 GTEX-Q734-1626-SM-48U1B GTEx Tissue Sample Gene Expression Profiles 1.0 1.00735 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7784 H3K36me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24952 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890667 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH211 CCLE Cell Line Gene CNV Profiles -1.0 -1.69299 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.01989 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.8519 H3K36me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null AAMP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73313 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.25702 GTEX-XV7Q-1426-SM-4BRWA GTEx Tissue Sample Gene Expression Profiles 1.0 1.00997 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05412 GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.26239 GTEX-NFK9-0008-SM-4E3JE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.901971 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 0.873094 GSE182680,GSE182683_5_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null DMRTA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1666 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.41361 GTEX-PLZ4-2826-SM-3P617 GTEx Tissue Sample Gene Expression Profiles 1.0 0.845077 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.85733 H3K36me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PSDG-0008-SM-48TE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62342 GSE236511_1_v_0_ngfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null MFAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10396 GTEX-OHPK-2626-SM-2HMK9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06591 GTEX-SUCS-0326-SM-32PLL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.890917 GSE206226_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83877 RAJI CCLE Cell Line Gene Expression Profiles 1.0 1.37983 MC116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43216 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47738 DMS153 CCLE Cell Line Gene Expression Profiles -1.0 -1.46966 SLBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19065 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7045 Perturb_4600_KO_Mettl3_SRP048598 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.885568 PFKL_OE_GDS4410_75_human_Biceps muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE196117_1_v_11_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.967716 GSE103068_0_v_1_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960352 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -2.29043 GTEX-RWS6-0626-SM-2XCAS GTEx Tissue Sample Gene Expression Profiles 1.0 1.18352 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1046 PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null CALU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.84564 GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8079 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99116 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11675 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31643 GSE153836_14_v_5_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.840906 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15806 SNU1033 DepMap CRISPR Gene Dependency 1.0 3.57981 MIS18BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08338 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.41032 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.25086 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67093 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.782 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -2.95689 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.873511 GSE169356_2_v_3_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2AphosphoS2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null H3K36me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XQ8I-0726-SM-4BOPU GTEx Tissue Sample Gene Expression Profiles 1.0 0.917774 PEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40591 NCIH28 DepMap CRISPR Gene Dependency 1.0 2.23305 STK11IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16797 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0379 GSE92562_2_v_0_cpeb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTDSPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19328 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.088 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04715 ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91647 GSE111247_11_v_4_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830046 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43448 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960352 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36621 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1633 GTEX-U8XE-0005-SM-3DB8I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.913137 NCIH2029 CCLE Cell Line Gene CNV Profiles -1.0 -1.41295 OVTOKO CCLE Cell Line Gene CNV Profiles -1.0 -1.58701 GTEX-X585-0011-R4B-SM-46MVH GTEx Tissue Sample Gene Expression Profiles 1.0 0.962117 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-T6MO-0008-SM-4DM6T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08377 ESCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14203 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.889431 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00475 H1_Cell_Line Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.02157 VPS37B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2344 GSE129241_3_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.26326 GTEX-O5YT-0226-SM-32PK5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870071 496100303_HIP_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.15351 inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936987 GTEX-OOBK-0008-SM-3NB27 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22188 NCIH841 CCLE Cell Line Gene Expression Profiles -1.0 -1.57829 mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-OHPL-0326-SM-33HC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03182 Perturb_15238_KD_TINCR_SRP082178 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.03131 smoothmuscle_8a HPA Tissue Sample Gene Expression Profiles 1.0 0.970826 hsa-miR-369-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE109530,GSE109531_1_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures 1.0 null UPCISCC029A DepMap CRISPR Gene Dependency 1.0 2.05073 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.850474 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42279 Endosome COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 ATPAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18833 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.4182 H3K36me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_3_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles 1.0 1.42436 MAGEE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58539 UMUC1 CCLE Cell Line Gene Expression Profiles -1.0 -1.83532 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48481 GATA1_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84942 RH4 DepMap CRISPR Gene Dependency 1.0 4.06876 PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.845546 u698 HPA Cell Line Gene Expression Profiles -1.0 -1.03557 GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53711 GTEX-P4QS-2026-SM-3NMCG GTEx Tissue Sample Gene Expression Profiles 1.0 0.923889 GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13053 GSE178292_0_v_3_melphalan_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 70.2703 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.833043 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48725 GSE153907,GSE153908_0_v_1_azathioprine_human RummaGEO Drug Perturbation Signatures 1.0 null 496100345_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06043 HA1E DepMap CRISPR Gene Dependency 1.0 2.75598 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.56417 GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.93915 Penis_Foreskin_Melanocyte_Primary_Cells_skin01 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.75433 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02322 SNU1214 CCLE Cell Line Gene CNV Profiles 1.0 1.67262 Fundus dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.566 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7744 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57948 GSE192663_3_v_5_acly_mouse RummaGEO Gene Perturbation Signatures -1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1645 Retinitis Pigmentosa DisGeNET Gene-Disease Associations 1.0 null PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09835 PKP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09342 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.5435 Vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.69016 GSE196117_1_v_0_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null COLO741 CCLE Cell Line Gene Expression Profiles 1.0 3.1294 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99116 GSE93674_2_v_3_ezh2_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6456 EE-03-SG02_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.334745 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.4921 IER3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24723 a431 HPA Cell Line Gene Expression Profiles -1.0 -1.93132 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 CTCF-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null TAL1_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21231 GTEX-WRHU-0926-SM-4E3IG GTEx Tissue Sample Gene Expression Profiles 1.0 0.836641 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.75711 Perturb_15753_KO_Ezh2_SRP096837 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -19.2218 GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.58453 anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890243 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7902 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25101 HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5585 GTEX-XLM4-0011-R4B-SM-4AT5C GTEx Tissue Sample Gene Expression Profiles 1.0 0.881857 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1795 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0241 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01085 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59389 GTEX-QXCU-0008-SM-48FCH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81837 SMN complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.32 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9936 Perturb_15828_OE_Nrf2_SRP291726 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.73559 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1795 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -2.25619 GTEX-RWS6-1726-SM-47JXP GTEx Tissue Sample Gene Expression Profiles 1.0 0.955708 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 1.49568 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.61242 GTEX-TSE9-0011-R8A-SM-3DB7R GTEx Tissue Sample Gene Expression Profiles 1.0 1.11619 GSE210662_2_v_0_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04627 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.51922 CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.3098 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.83442 CHMP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55008 GTEX-OHPM-0008-SM-4E3IP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18328 GTEX-S32W-1226-SM-4AD67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.943806 GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.59284 ubiquitin binding GO Molecular Function Annotations 2023 1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34054 GSE140651,GSE140653_2_v_1_med1_human RummaGEO Gene Perturbation Signatures -1.0 null HUES64_Cell_Line Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.53445 GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936407 Perturb_5107_OE_Yy1_SRP281855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 MNAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75254 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07842 skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles 1.0 0.96978 SNU1077 CCLE Cell Line Gene Expression Profiles -1.0 -1.57476 GSE148200_1_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null H3K36me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FANCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17468 GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.989412 SUM52PE DepMap CRISPR Gene Dependency 1.0 2.95175 GSE112763,GSE112767_4_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_7_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-O5YT-0008-SM-4E3IQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81071 ATG101 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52037 GTEX-N7MS-0008-SM-4E3JI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21227 RPMI8226 CCLE Cell Line Gene CNV Profiles 1.0 1.42781 SNU5 DepMap CRISPR Gene Dependency 1.0 2.40387 substantia nigra, pars compacta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1955 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31207 GSE213588_10_v_5_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6647 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.900482 Bladder GTEx Tissue Gene Expression Profiles 2023 1.0 4.11029 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.97393 PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.58716 GTEX-Q734-0526-SM-2I3EH GTEx Tissue Sample Gene Expression Profiles 1.0 0.998473 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11074 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2166 PNMA8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12964 GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.8601 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.5228 GTEX-S33H-0008-SM-4AD6C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982064 GSE191021_1_v_0_nono_human RummaGEO Gene Perturbation Signatures -1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07874 SK-MEL-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.537 H4K20me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.1523 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.08111 GTEX-SNMC-0126-SM-2XCFO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03142 GSE169152_5_v_7_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null SLC25A28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30852 COLO775 CCLE Cell Line Gene CNV Profiles 1.0 1.33915 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.19551 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.99174 Perturb_5144_KO_H3f3a_ERP109384 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.02618 Penis_Foreskin_Melanocyte_Primary_Cells_skin03 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.988821 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.9091 ZNF667 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23802 IZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01623 GSE248858_1_v_7_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81771 CYBC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16003 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9434 PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC Rummagene Transcription Factor Associations 2026 1.0 null FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.839 VTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34947 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.88462 GTEX-WWYW-0826-SM-3NB2X GTEx Tissue Sample Gene Expression Profiles 1.0 0.908972 GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K36me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12648_KD_Igfbp5_SRP191022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.2076 GSC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1454 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28041 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.51728 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02322 SET2 DepMap CRISPR Gene Dependency 1.0 4.84522 496100453_HIP_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.78743 GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4826 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.99732 GSE114992,GSE114993_9_v_2_irf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-P4QT-2026-SM-3NMCJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.922497 496100622_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.9538 MIGA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4327 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02358 Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.6264 GTEX-S4Z8-0726-SM-4GICB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885572 H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PYGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16814 GTEX-Q734-0726-SM-48TZP GTEx Tissue Sample Gene Expression Profiles 1.0 0.879578 GTEX-QDT8-2926-SM-32PKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.23172 GTEX-U3ZM-0008-SM-4DXTQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877719 GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00152 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8025 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2366 outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924824 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.890195 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885721 GTEX-N7MT-0011-R3a-SM-2I3GC GTEx Tissue Sample Gene Expression Profiles 1.0 1.18908 TAL1_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PGK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54678 PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22408 GTEX-Q2AH-0008-SM-48U2J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891252 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33147 GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07258 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0441 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890537 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3155 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4147 paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29046 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.12018 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28869 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.863247 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830991 GSE140651,GSE140653_2_v_4_med1_human RummaGEO Gene Perturbation Signatures -1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58564 CD4_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.3069 granular layer of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946882 GSE201239_6_v_7_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WFG7-0008-SM-4LMKB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88768 heart GTEx Tissue Gene Expression Profiles -1.0 -1.04989 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null F11R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07936 GTEX-Q2AG-0011-R8A-SM-2HMK5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.909891 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2805 GTEX-SIU7-0001-SM-3NMAW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.946694 GSE81193_0_v_4_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.979976 Extraocular muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.617 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2894 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.943553 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04014 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76377 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8352 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.4045 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15211 GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 2.03524 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.421 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916913 GSE197850_4_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T6MO-1026-SM-4DM72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08953 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 51.75 GSE232564,GSE232566_3_v_1_nsd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.57265 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79762 SNU738 CCLE Cell Line Gene CNV Profiles -1.0 -2.18379 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.3848 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.951096 ZNF415 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93936 CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92943 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46708 CAVIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0627 GSE215461_0_v_1_topotecan_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28817 CD4_Memory_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.896878 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21074 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 2.09159 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41432 PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null NCIH2196 CCLE Cell Line Gene CNV Profiles -1.0 -1.54726 PFKL_OE_GDS4410_202_human_biceps GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE60217_1_v_0_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19333 SPAG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46281 GSE210093_3_v_2_taf15_human RummaGEO Gene Perturbation Signatures 1.0 null NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0625 TM9SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67674 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01513 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77726 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1053 NB1643 DepMap CRISPR Gene Dependency 1.0 4.94521 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15664 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.59223 RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05535 PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA Rummagene Transcription Factor Associations 2026 1.0 null MED12L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01129 SETDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62603 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.7625 BAZ1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55546 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.77313 IGR37 CCLE Cell Line Gene Expression Profiles 1.0 2.25899 ECGI10 CCLE Cell Line Gene CNV Profiles -1.0 -1.32389 GTEX-XMD1-0008-SM-4AT41 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836275 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8713 GSE68925_1_v_0_fasudil_human RummaGEO Drug Perturbation Signatures 1.0 null DCLRE1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34134 GSE60217_1_v_2_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null NHEJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48779 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24856 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959021 PMC10245467-mmc3.pdf-162-ZNF98_ZNF98 Rummagene Transcription Factor Associations 2026 1.0 null GSE171572_0_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9797 orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.901668 GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 2.10724 GSE218060_1_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null CGN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36184 PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF Rummagene Transcription Factor Associations 2026 1.0 null UNC13B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66503 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.86451 GSE158834_12_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null CNKSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5517 KCTD20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09931 LZTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44643 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06319 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1894 OTX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8479 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6096 hippocampus (hippocampal formation)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.973851 GTEX-P4QR-0008-SM-48TE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33796 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3629 COLO792 CCLE Cell Line Gene Expression Profiles 1.0 2.13763 H3K36me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16662 GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.6987 CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GSE240386,GSE242143_1_v_5_morc2_human RummaGEO Gene Perturbation Signatures -1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null GSE193402_0_v_1_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-SE5C-0626-SM-2XCDV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12481 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null GSE139348,GSE139349_1_v_0_dicer1_mouse RummaGEO Gene Perturbation Signatures -1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00649 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0447 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.52174 PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null LN18 DepMap CRISPR Gene Dependency 1.0 2.98339 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.96928 KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.87318 ECC4 DepMap CRISPR Gene Dependency 1.0 3.9515 HSF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17046 GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 2.19188 U266B1 CCLE Cell Line Gene CNV Profiles 1.0 1.36997 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 0.86204 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.4832 GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.87253 INKA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8137 GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835054 GSE178418_1_v_0_traf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03783 GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 1.01885 GSE158320,GSE183351_2_v_3_lin28b_human RummaGEO Gene Perturbation Signatures 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.964988 PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2146 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01594 GTEX-P4PP-0008-SM-48TDV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44309 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5677 CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20423 Perturb_13435_KD_Zc3h13_SRP098937 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.45526 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.902269 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5564 FOXG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3662 JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.998582 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.98121 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12 Retinal pigment epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.393 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3631 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09962 GTEX-O5YW-0326-SM-2I5EI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13555 GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 2.40377 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 1.04361 GSE171572_1_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null GSE154253_1_v_0_tnfaip8_human RummaGEO Gene Perturbation Signatures 1.0 null GSE224763_1_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HDHD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45447 GTEX-UJHI-1226-SM-4IHLR GTEx Tissue Sample Gene Expression Profiles 1.0 1.35001 SKMEL30 DepMap CRISPR Gene Dependency 1.0 2.18343 DHX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5117 GTEX-R55E-0011-R8A-SM-2TC66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02916 GSE196343_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PWOO-0926-SM-2I3EC GTEx Tissue Sample Gene Expression Profiles 1.0 0.995638 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.92516 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.892651 Retinal cone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.276 GTEX-U4B1-0626-SM-3DB8L GTEx Tissue Sample Gene Expression Profiles 1.0 1.00154 GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.7397 TPCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5204 C33A DepMap CRISPR Gene Dependency 1.0 6.97435 NTERA2CLD1 DepMap CRISPR Gene Dependency 1.0 2.85476 H3K36me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.95753 hsa-miR-4720-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5427 supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.967347 GSE226285_3_v_0_nr0b1_human RummaGEO Gene Perturbation Signatures 1.0 null FKBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03818 GTEX-XUZC-0008-SM-4BOQG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916082 GSE120413,GSE120447_0_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 0.944985 SKNFI CCLE Cell Line Gene CNV Profiles 1.0 1.45868 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62815 GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824199 Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 GTEX-X4XX-0926-SM-46MV7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15799 GTEX-SE5C-0008-SM-4B64J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936662 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14925_OE_HsATXN3_SRP155020 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.69807 NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3245 GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 2.56403 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.78897 RPS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22492 GTEX-X4XX-0011-R4B-SM-46MWL GTEx Tissue Sample Gene Expression Profiles 1.0 0.903504 PMC9669639-mmc3.xlsx-NRLonly-degs-207-Single_cell_RNA-seq_differentially_expressed_genes_between_control_versus_USH1B_NRL_cells_NRL Rummagene Transcription Factor Associations 2026 1.0 null PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 1.38705 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02745 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839428 GTEX-XYKS-0226-SM-4BRW3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934597 GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles 1.0 0.86303 substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.909785 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.78508 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.6203 primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.847031 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.55845 POFUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62525 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.961324 mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0127 GSE101239_5_v_6_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null SNU685 CCLE Cell Line Gene Expression Profiles -1.0 -1.79453 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.68492 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4867 PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879342 endometrium_4b HPA Tissue Sample Gene Expression Profiles 1.0 1.61149 GTEX-XUW1-0626-SM-4BOP4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17495 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60584 GIMEN DepMap CRISPR Gene Dependency 1.0 2.88022 RSBN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99514 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.16249 GTEX-TSE9-2226-SM-4DXUR GTEx Tissue Sample Gene Expression Profiles 1.0 0.911942 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9714 GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.896924 Perturb_234_KD_MITF_SRP048577 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.1688 SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.65451 GSE202434,GSE202438_10_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X585-0011-R5A-SM-46MVI GTEx Tissue Sample Gene Expression Profiles 1.0 1.2849 subiculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17864 endometrium_8a HPA Tissue Sample Gene Expression Profiles 1.0 1.50366 VMRCLCP CCLE Cell Line Gene CNV Profiles 1.0 2.41481 DMS79 CCLE Cell Line Gene CNV Profiles -1.0 -1.5797 GTEX-X4XX-0011-R2A-SM-3P623 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26521 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO Biological Process Annotations 2023 1.0 null dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.37885 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0244 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.718 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.05352 PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.03834 496100555_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24699 GTEX-WEY5-0426-SM-3GIKT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21081 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07746 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.6152 GSE81796_0_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.029 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.82899 U118MG CCLE Cell Line Gene Expression Profiles -1.0 -1.66521 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.05158 ovary GTEx Tissue Gene Expression Profiles 1.0 0.903095 GTEX-QDVJ-0426-SM-2I5FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10707 H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.8693 DCAF13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24492 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29151 GSE224877_3_v_0_pctp_mouse RummaGEO Gene Perturbation Signatures 1.0 null NOTCH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01383 H3K36me3_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13503 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.833329 PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null NEUROG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2257 OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2287 GSE169205_0_v_7_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE154961,GSE154963_4_v_0_chd4_human RummaGEO Gene Perturbation Signatures 1.0 null SMPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21945 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15222 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01766 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9179 skin HPA Tissue Gene Expression Profiles 1.0 0.875313 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85622 hsa-miR-4799-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8966 ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.2509 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74825 GSE164874_5_v_12_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.7944 GTEX-XMD1-0826-SM-4AT52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.921779 GTEX-OXRK-0008-SM-3NB28 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40939 RASGRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02193 SP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.83113 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.42653 GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 0.924993 GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.96196 UMUC16 DepMap CRISPR Gene Dependency 1.0 2.48522 primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.88766 GSE196117_6_v_0_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null T3M4 DepMap CRISPR Gene Dependency 1.0 2.76007 MRGPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81166 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE262134_0_v_1_dnajc12_human RummaGEO Gene Perturbation Signatures -1.0 null GSE213588_8_v_5_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71472 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.61163 GTEX-N7MS-0011-R10A-SM-2HMJK GTEx Tissue Sample Gene Expression Profiles 1.0 0.935089 GSE219195_4_v_2_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null GSE118077_7_v_2_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92141 Sox6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.4177 NAT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36425 GTEX-RU72-2626-SM-4GIE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30014 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985491 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.99138 GSE148321,GSE169423_2_v_1_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05863 H3K36me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93071 skmel30 HPA Cell Line Gene Expression Profiles 1.0 1.76439 pancreas_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.26642 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.996334