association	dataset	threshold value	standardized value
Ino80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.47871
U2-type catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
CORO1B	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50943
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04438
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58638
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
DHX58	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11595
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE-671 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
MYL12A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4346-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837856
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.875344
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG-19300518-3T3-L1 preadipocyte cells-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5069771__F2	PFOCR Pathway Figure Associations 2023	1.0	null
PPARA_Deficiency_GDS2934_632_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Follicular dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
PPP2R3B	Pathway Commons Protein-Protein Interactions	1.0	null
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
Multivesicular body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypersensitivity	CTD Gene-Disease Associations	1.0	1.15089
EKVX	DepMap CRISPR Gene Dependency	1.0	2.14394
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5726
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
Perturb_9564_KO_Nfkb2_SRP256294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.04316
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
autofat10ylated	GeneRIF Biological Term Annotations	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830066
AUP1	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31585
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
response to organic substance	GO Biological Process Annotations 2015	1.0	null
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1529
ILF2_02_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.63028
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044096
tropical	GeneRIF Biological Term Annotations	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70067
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10236
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bark	GeneRIF Biological Term Annotations	1.0	null
ZNF280D	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
pg4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USO1	Pathway Commons Protein-Protein Interactions	1.0	null
PFAS	Pathway Commons Protein-Protein Interactions	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CCDC22	Pathway Commons Protein-Protein Interactions	1.0	null
Fish- and plant-related diet	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58814
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9553
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03887
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3CL	Pathway Commons Protein-Protein Interactions	1.0	null
ASB7	Pathway Commons Protein-Protein Interactions	1.0	null
ACOT9	Pathway Commons Protein-Protein Interactions	1.0	null
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
niacin_mus musculus_gpl1261_gds2605	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.935335
Perturb_3816_KO_Rb1_SRP062249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5439
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.82481
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G3-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ER ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
several	GeneRIF Biological Term Annotations	1.0	null
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.508
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839461
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-8501-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Van den Ende-Gupta syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
AMBRA1	Pathway Commons Protein-Protein Interactions	1.0	null
UBE2S	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934835
RGP1	Pathway Commons Protein-Protein Interactions	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
lacking	GeneRIF Biological Term Annotations	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274394
ARMC6	Pathway Commons Protein-Protein Interactions	1.0	null
NKX2-1_01_66	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.59695
POLB	Pathway Commons Protein-Protein Interactions	1.0	null
strategy	GeneRIF Biological Term Annotations	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prostate adenocarcinoma_PRAD_TCGA-HC-7233-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Molybdopterin synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
GCC1	Pathway Commons Protein-Protein Interactions	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92246
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.436375
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29645
DHRS7B	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAGED4	Pathway Commons Protein-Protein Interactions	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3436
efficiently	GeneRIF Biological Term Annotations	1.0	null
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76593
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28764
regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397222
enhanced	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
Peyer's gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
16938647-Table2b	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54091
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353763
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0034
SLC25A6	Pathway Commons Protein-Protein Interactions	1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
GFAP	Pathway Commons Protein-Protein Interactions	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.021
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52386
cellular macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulating	GeneRIF Biological Term Annotations	1.0	null
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78623
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259591
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54995
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1912
RUNDC1	Pathway Commons Protein-Protein Interactions	1.0	null
positive regulation of cell death	GO Biological Process Annotations 2015	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Neutropenia	CTD Gene-Disease Associations	1.0	1.08655
mediating	GeneRIF Biological Term Annotations	1.0	null
GSE145476_1_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.78682
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CAV3_KO_GDS3533_357_mouse_mammalian glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC9335103__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.194045
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.709016
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.596242
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
colocalizes	GeneRIF Biological Term Annotations	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.61902
SNU398	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57431
PMC12486367-Supplementary_Data2.pdf-437-ZNF837_ZNF837	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.17142
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963601
HIST1H2BL	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853408
PMC3836475__F4	PFOCR Pathway Figure Associations 2023	1.0	null
reaction	GeneRIF Biological Term Annotations	1.0	null
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971506
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.072
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83918
PKP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58219
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.702103
hsa-miR-4474-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFT74	Pathway Commons Protein-Protein Interactions	1.0	null
CPSF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KBTBD6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3379
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51148
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67361
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05583
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885625
SKIV2L	Pathway Commons Protein-Protein Interactions	1.0	null
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
FLG2	Pathway Commons Protein-Protein Interactions	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.457987
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1269
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EIF3A	Pathway Commons Protein-Protein Interactions	1.0	null
hepa 1-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02644
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86745
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCS1L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98705_1_v_0_mdm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17816
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18834
RAE1	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23078
TNFAIP2	Pathway Commons Protein-Protein Interactions	1.0	null
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
RH28	DepMap CRISPR Gene Dependency	1.0	2.18325
modification	GeneRIF Biological Term Annotations	1.0	null
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18754
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934337
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XC-50-TN39_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33902
DYNC1I1	Pathway Commons Protein-Protein Interactions	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.143
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4591983__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995843
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175947
ASXL1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5417597-pone.0176679.s006.xlsx-Tumor_MLL_vs_Control-Unnamed_1_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855447
RANBP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nub1l	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05826
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951651
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.28622
RPS5	Pathway Commons Protein-Protein Interactions	1.0	null
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE236072,GSE236075_2_v_1_ccr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04117
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38271
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831309
Perturb_11223_KO_Mkrn1_SRP149173	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	2.88009
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.29256
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.922
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.48614
GSE165548_2_v_7_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02726
positive regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88558
positive regulation of programmed cell death	GO Biological Process Annotations 2023	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53963
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
KIAA0368	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6118_KO_Fak_SRP279401	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.71799
cell part	GO Cellular Component Annotations 2015	1.0	null
KDM4D	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-550b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TPP2	Pathway Commons Protein-Protein Interactions	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17555
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08149
colon	GeneRIF Biological Term Annotations	1.0	null
dementia	GWASdb SNP-Disease Associations	1.0	0.326539
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOMM70A	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
UTP15	Pathway Commons Protein-Protein Interactions	1.0	null
reduction	GeneRIF Biological Term Annotations	1.0	null
pioglitazone_rattus norvegicus_gpl341_liver_gds3850	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
accelerated	GeneRIF Biological Term Annotations	1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851929
CBX4	Pathway Commons Protein-Protein Interactions	1.0	null
TGFBR1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
antigenic	GeneRIF Biological Term Annotations	1.0	null
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GMPPA	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.702103
GUF1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7866
KIAA1279	Pathway Commons Protein-Protein Interactions	1.0	null
PKCA_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
NCF2	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45791
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lymphoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186997
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15896
participates	GeneRIF Biological Term Annotations	1.0	null
e1l2	GeneRIF Biological Term Annotations	1.0	null
ubiquitin	GeneRIF Biological Term Annotations	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0729
SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.44653
HSF1_01_178	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.30685
PANC0213	CCLE Cell Line Gene Expression Profiles	1.0	1.71883
FKBP8	Pathway Commons Protein-Protein Interactions	1.0	null
POR_KO_GDS1678_760_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
endosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429072
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51746
SARS-CoV MA15_Day2-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.939267
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
marker	GeneRIF Biological Term Annotations	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
18464117-Table2	GeneSigDB Published Gene Signatures	1.0	null
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34957
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886272
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81354
IKBKAP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202587_1_v_2_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
GSE148692,GSE148695_1_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69502
EIF2S3	Pathway Commons Protein-Protein Interactions	1.0	null
EID3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
RAD51AP1	Pathway Commons Protein-Protein Interactions	1.0	null
SRP68	Pathway Commons Protein-Protein Interactions	1.0	null
RNF186	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969214
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20149
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.300704
MET_knockout_249_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.18874
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MSH6	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myeloid dendritic cell differentiation	GO Biological Process Annotations 2023	1.0	null
c-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.425138
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44715
proteasome	GeneRIF Biological Term Annotations	1.0	null
FBXO3	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A8BQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27831
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hlaa2restricted	GeneRIF Biological Term Annotations	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
myeloid leukocyte differentiation	GO Biological Process Annotations 2023	1.0	null
activates	GeneRIF Biological Term Annotations	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
GSE183890_2_v_6_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.02151
degrees	GeneRIF Biological Term Annotations	1.0	null
PRPF8	Pathway Commons Protein-Protein Interactions	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.818993
CXorf57	Pathway Commons Protein-Protein Interactions	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
binds	GeneRIF Biological Term Annotations	1.0	null
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
KPNA2	Pathway Commons Protein-Protein Interactions	1.0	null
able	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31797
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
inclusion body	GO Cellular Component Annotations 2015	1.0	null
modification-dependent macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
CSNK1E	Pathway Commons Protein-Protein Interactions	1.0	null
NAA20	Pathway Commons Protein-Protein Interactions	1.0	null
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.31464
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21962
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15004
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
abnormal immune system physiology	MPO Gene-Phenotype Associations	1.0	null
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194232
abnormal seminal vesicle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
DRG1	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0509
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916507
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLUH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11075_KO_Rictor_SRP097622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3485
mcm complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.332848
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subunit	GeneRIF Biological Term Annotations	1.0	null
DLX5_OE_GDS4577_345_mouse_Otic vesicle derived 2B1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55845
Alcoholic hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
PCNA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.206
GSE201882,GSE201883_3_v_2_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_144_KD_Tmbim1_SRP319088	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GIMEN	DepMap CRISPR Gene Dependency	1.0	3.34172
MHC class II protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
positive regulation of canonical NF-kappaB signal transduction	GO Biological Process Annotations 2025	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52608
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12003903-41531_2025_933_MOESM1_ESM.pdf-19-ENSG00000096654_ZNF184	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87116
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52592
CNOT8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
KLHL22	Pathway Commons Protein-Protein Interactions	1.0	null
acetaminophen_homo sapiens_gpl6244_gse27420	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58325
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	2.0666
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.48425
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30398
NPEPPS	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRP19	Pathway Commons Protein-Protein Interactions	1.0	null
FAM126B	Pathway Commons Protein-Protein Interactions	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
showed	GeneRIF Biological Term Annotations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75957
Endoplasmic reticulum quality control compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5173
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10531
16373702-Table2b	GeneSigDB Published Gene Signatures	1.0	null
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPP5	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05972
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
GSE149854_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stomach Neoplasms	CTD Gene-Disease Associations	1.0	1.30117
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08192
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89345
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063112
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839452
PMC7868042__F2	PFOCR Pathway Figure Associations 2023	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15349
hsa-miR-3147	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872888
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30844
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0682
NANOG	ChEA Transcription Factor Targets	1.0	null
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.35494
18172295-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
myeloid dendritic cell differentiation	GO Biological Process Annotations 2025	1.0	null
FOS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08114
Weight Gain	CTD Gene-Disease Associations	1.0	1.4164
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52196
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44721
glioma	GeneRIF Biological Term Annotations	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.37955
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399871
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPTLC1	Pathway Commons Protein-Protein Interactions	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494528
PCBP1_02_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.9262
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS15	Pathway Commons Protein-Protein Interactions	1.0	null
GD-46-OD81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266225
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	1.35657
Perturb_14216_KO_Igf1r_SRP081104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.20143
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.32415
burkitt lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114607
chromosomal	GeneRIF Biological Term Annotations	1.0	null
Paget's disease of bone	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
ABCF2	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
15720813-Table1	GeneSigDB Published Gene Signatures	1.0	null
PMC7786291-Table_1.xlsx-Table_S1-Supplementary_table_1_ETV7-related_genes_in_the_TCGA_SKCM_data_set_ETV7	Rummagene Transcription Factor Associations 2026	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	4.68476
STRN4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11073_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
peptide	GeneRIF Biological Term Annotations	1.0	null
deletion	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943577
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2023	1.0	null
GSPT1	Pathway Commons Protein-Protein Interactions	1.0	null
diagnostic	GeneRIF Biological Term Annotations	1.0	null
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80117
NXF1	Pathway Commons Protein-Protein Interactions	1.0	null
OE-04-VO07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439616
FDFT1	Pathway Commons Protein-Protein Interactions	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061468
hsa-miR-576-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
inhibition	GeneRIF Biological Term Annotations	1.0	null
Ubp3-Bre5 deubiquitination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07668
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cul2-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ER membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.82037
PDK3	Pathway Commons Protein-Protein Interactions	1.0	null
MYH10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993268
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2376
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91741
chromosome	GeneRIF Biological Term Annotations	1.0	null
IFRD2	Pathway Commons Protein-Protein Interactions	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
SARM1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04775
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
DES	Pathway Commons Protein-Protein Interactions	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31705
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05929
UBE3A	Pathway Commons Protein-Protein Interactions	1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03567
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07266
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828655
multiple myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14419
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30853
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
lrrfip2	GeneRIF Biological Term Annotations	1.0	null
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological	GeneRIF Biological Term Annotations	1.0	null
CS	Pathway Commons Protein-Protein Interactions	1.0	null
CCDC93	Pathway Commons Protein-Protein Interactions	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central	GeneRIF Biological Term Annotations	1.0	null
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.22741
NOC2L	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52592
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14425
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Fibrosis	CTD Gene-Disease Associations	1.0	2.02824
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053516
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulatory	GeneRIF Biological Term Annotations	1.0	null
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05752
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-0726-SM-4JBH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74381
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922465
TWIST1_01_254	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.67803
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	2.83073
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Conserved_gene_regulation_during_acute_inflammation_between_zebrafish_and_mammals_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
response to tumor necrosis factor	GO Biological Process Annotations 2015	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09235
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.028
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7303
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22745
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
USP11	Pathway Commons Protein-Protein Interactions	1.0	null
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859655
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIAPH3	Pathway Commons Protein-Protein Interactions	1.0	null
INTS5	Pathway Commons Protein-Protein Interactions	1.0	null
ESCRT II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.682
Karyomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41469
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05262
Sarcoma_SARC_TCGA-UE-A6QT-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Elongin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
CCDC138	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5069771__F2	PFOCR Pathway Figure Associations 2024	1.0	null
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
Proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.624
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45931
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7583-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828763
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7133
AMMECR1L	Pathway Commons Protein-Protein Interactions	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.043171
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.659611
manner	GeneRIF Biological Term Annotations	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	0.702103
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23117
Lung adenocarcinoma_LUAD_TCGA-95-7944-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Heart_GSE9377_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SCH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
HYOU1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16298
DDX6	Pathway Commons Protein-Protein Interactions	1.0	null
nondisjunction	GeneRIF Biological Term Annotations	1.0	null
UPRT	Pathway Commons Protein-Protein Interactions	1.0	null
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.23776
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169091
myeloid dendritic cell activation	GO Biological Process Annotations 2025	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.28703
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4259	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Pneumonia	CTD Gene-Disease Associations	1.0	1.44572
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC1A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81306
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11069_OE_Ccne1_SRP185695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0982
TFG	Pathway Commons Protein-Protein Interactions	1.0	null
SH3GLB1	Pathway Commons Protein-Protein Interactions	1.0	null
ENO2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203158_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64767
STAT3	ChEA Transcription Factor Targets	1.0	null
studies	GeneRIF Biological Term Annotations	1.0	null
EIF3E	Pathway Commons Protein-Protein Interactions	1.0	null
troglitazone_rattus norvegicus_gpl341_liver_gds3850	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_KO_GSE39009_49_mouse_skeletal muscle (6 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
another	GeneRIF Biological Term Annotations	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83765
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629
ACADM	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32422
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09235
ZYG11B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary Biliary Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869427
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4465
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE230283_1_v_0_birc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46252
PMC6607389__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958698
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905914
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05341
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30083
regulation of cell cycle phase transition	GO Biological Process Annotations 2025	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADNP-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29974
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Necrosis	CTD Gene-Disease Associations	1.0	2.45842
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.55231
MYO1B	Pathway Commons Protein-Protein Interactions	1.0	null
STX11	Pathway Commons Protein-Protein Interactions	1.0	null
GSN	Pathway Commons Protein-Protein Interactions	1.0	null
diubiquitin	GeneRIF Biological Term Annotations	1.0	null
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
RECQL	Pathway Commons Protein-Protein Interactions	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78354
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51042
versus	GeneRIF Biological Term Annotations	1.0	null
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.67645
DUSP1_KO_GDS1606_773_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
stam2	GeneRIF Biological Term Annotations	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08273
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.6817
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.99786
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116017
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46134
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5019
partner	GeneRIF Biological Term Annotations	1.0	null
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029827
PELO	Pathway Commons Protein-Protein Interactions	1.0	null
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94255
Proteasome core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.753
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52339
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATAD3B	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01069
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32318
UPF1	Pathway Commons Protein-Protein Interactions	1.0	null
increase	GeneRIF Biological Term Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75999
only	GeneRIF Biological Term Annotations	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
modifier	GeneRIF Biological Term Annotations	1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
SPANXN4	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6842
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32678
XBP1_OE_GDS5065_273_mouse_F424a adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68629
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
IK	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
increased CD4-positive, CD25-positive NK T cell number	IMPC Knockout Mouse Phenotypes	1.0	null
Multivesicular body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.462
Woodhouse-Sakati syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
20332630-Table4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836206
ubiquitinconjugating	GeneRIF Biological Term Annotations	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.454
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216528
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08199
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.91179
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal immune cell physiology	MPO Gene-Phenotype Associations	1.0	null
syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0529
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7282
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cis	GeneRIF Biological Term Annotations	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
reproduction	GAD High Level Gene-Disease Associations	1.0	0.293278
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.47244
SRSF9	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
GPR120_KO_GDS4830_414_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15349
18180321-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
t56-vastus-lateralis_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-7.0193
increased cell death	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04815
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
GSE183890_2_v_10_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
b-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.519253
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PRKCA_KO_GDS2141_300_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.850425
SERTAD1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL27A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
diseases	GeneRIF Biological Term Annotations	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839452
PMC11554218-ppat.1012673.s015.xlsx-Sheet_A-IRF1_Target_Gene_Lists_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922688
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97P-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT19	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13278_KO_Mettl3_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.47383
SENP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.4026
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14748
PMC6475113__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.104
ACSL3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03184
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54858
proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.06751
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78359
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39273
HLA-E	Pathway Commons Protein-Protein Interactions	1.0	null
RPSA	Pathway Commons Protein-Protein Interactions	1.0	null
occurs	GeneRIF Biological Term Annotations	1.0	null
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.2352
aggresome assembly	GO Biological Process Annotations 2015	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456055
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00668
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82714
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02904
lymphnode	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839452
IER5	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PZ-HPV-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
PRKCI	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	0.702103
DUSP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SHP77	DepMap CRISPR Gene Dependency	1.0	2.82153
DUSP1_KO_GDS1606_772_mouse_spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.274378
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4626
Perturb_17773_OE_Tgfb1_SRP325964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.69493
SRPK1	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
cold-induced sweating syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
gastric	GeneRIF Biological Term Annotations	1.0	null
regulation of I-kappaB kinase/NF-kappaB signaling	GO Biological Process Annotations 2023	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69148
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873313
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
Perturb_4983_Mut_Tet2_SRP111192	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.33454
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12198
GSE134896_0_v_7_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91852
Liver hepatocellular carcinoma_LIHC_TCGA-O8-A75V-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-93-RZ62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330418
HAUS3	Pathway Commons Protein-Protein Interactions	1.0	null
positive regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
screened	GeneRIF Biological Term Annotations	1.0	null
BXPC3	DepMap CRISPR Gene Dependency	1.0	2.60152
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24507
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226926
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Rectum adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Atg1/ULK1 kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78723
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901685
LYPLAL1	Pathway Commons Protein-Protein Interactions	1.0	null
MAGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15112
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02904
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
multiple sclerosis	GAD Gene-Disease Associations	1.0	null
TMA7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874594
proteolysis	GO Biological Process Annotations 2025	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
PSMD10	Pathway Commons Protein-Protein Interactions	1.0	null
Cul3-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphocytic Choriomeningitis	DisGeNET Gene-Disease Associations	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04276
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7862443__F2	PFOCR Pathway Figure Associations 2024	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40145
Sarcoma_SARC_TCGA-DX-AB2Z-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3648157__F7	PFOCR Pathway Figure Associations 2023	1.0	null
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.384665
inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.243295
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.00299
demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.234225
LGALS1	Pathway Commons Protein-Protein Interactions	1.0	null
knockdown	GeneRIF Biological Term Annotations	1.0	null
ACTG1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFV	Pathway Commons Protein-Protein Interactions	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054256
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360782
aipl1	GeneRIF Biological Term Annotations	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
VCP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bcl3/NF-kappaB2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
IM95	DepMap CRISPR Gene Dependency	1.0	3.06786
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RIDDLE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36652
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48383
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36257
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29974
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.95195
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638404
FHL2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7444072__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aids (Disease)	DisGeNET Gene-Disease Associations	1.0	null
NFKB2	Pathway Commons Protein-Protein Interactions	1.0	null
SCH	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3238
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4846-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
recognition	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.139
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23117
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45337
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60713
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833338
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21463
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DEGS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	2.00002
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34299
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
PSAT1	Pathway Commons Protein-Protein Interactions	1.0	null
DDX18	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77454
GSE141453,GSE141454_0_v_4_card11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.25059
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
HEPG2	CCLE Cell Line Gene Expression Profiles	1.0	1.51774
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226411
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDHD1	Pathway Commons Protein-Protein Interactions	1.0	null
TBKBP1	Pathway Commons Protein-Protein Interactions	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72999
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.239
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.42438
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937944
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.975062
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
Biliary Cirrhosis, Primary, 1	DisGeNET Gene-Disease Associations	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4923
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13034
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.434906
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4181
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.607395
PSMC2	Pathway Commons Protein-Protein Interactions	1.0	null
evidence	GeneRIF Biological Term Annotations	1.0	null
OCIAD1	Pathway Commons Protein-Protein Interactions	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
1221 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
im-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445653
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
distinct	GeneRIF Biological Term Annotations	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	4.22777
ERMP1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13967
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97372
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.89247
GSE171269_1_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7029
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980921
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.508808
PMC3348545-NIHMS263168-supplement-3.pdf-198-ZNF250_ZNF250	Rummagene Transcription Factor Associations 2026	1.0	null
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11309
UFD1-NPL4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.786
hsa-miR-24-3p	MiRTarBase microRNA Targets	1.0	null
ASNSD1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72629
multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151133
CAPAN1	DepMap CRISPR Gene Dependency	1.0	7.30322
Delta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
cycle	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73924
IPO9	Pathway Commons Protein-Protein Interactions	1.0	null
resulted	GeneRIF Biological Term Annotations	1.0	null
Myosin IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
retinal	GeneRIF Biological Term Annotations	1.0	null
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AARS	Pathway Commons Protein-Protein Interactions	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56349
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22302
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00627
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M1-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.829089
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.76142
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31201
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897194
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.028
abnormal thymus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
PMC5866017__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
PRR15	Pathway Commons Protein-Protein Interactions	1.0	null
TBC1D22B	Pathway Commons Protein-Protein Interactions	1.0	null
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048004
immune system phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
mitotic	GeneRIF Biological Term Annotations	1.0	null
BRCA1-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.564
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0656
system	GeneRIF Biological Term Annotations	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.08904
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71646
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15064
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55591
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51272
AP1M1	Pathway Commons Protein-Protein Interactions	1.0	null
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68604
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6645
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58446
PSMA6	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08452
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.549773
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0592
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827464
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35873
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMD13	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
DARS2	Pathway Commons Protein-Protein Interactions	1.0	null
telomeric	GeneRIF Biological Term Annotations	1.0	null
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
CBM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54515
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.2279
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862395
BNC1_KD_GDS1978_738_mouse_Oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZR-75-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
cellular process	GO Biological Process Annotations 2015	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
Lung adenocarcinoma_LUAD_TCGA-44-A4SS-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
apoptosis	GeneRIF Biological Term Annotations	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38453
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
TPM1	Pathway Commons Protein-Protein Interactions	1.0	null
RPN1	Pathway Commons Protein-Protein Interactions	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.87282
bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.494648
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55607
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
GSE104022_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lys63	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pp65	GeneRIF Biological Term Annotations	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.35375
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.833263
Carcinoma	CTD Gene-Disease Associations	1.0	1.93088
modulate	GeneRIF Biological Term Annotations	1.0	null
Field CA1, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03659
single	GeneRIF Biological Term Annotations	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
INTS4	Pathway Commons Protein-Protein Interactions	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058511
degraded	GeneRIF Biological Term Annotations	1.0	null
HT-1376	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1182
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.42325
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97546
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.75144
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Perturb_11129_KO_Yap1_SRP281955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YWHAZ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
proteasome activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266042
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.88763
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648938
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855967
NOP2	Pathway Commons Protein-Protein Interactions	1.0	null
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27598
implicate	GeneRIF Biological Term Annotations	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.229
H2AFZ	Pathway Commons Protein-Protein Interactions	1.0	null
MYO19	Pathway Commons Protein-Protein Interactions	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
HDAC3	Pathway Commons Protein-Protein Interactions	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74119
ACTR3	Pathway Commons Protein-Protein Interactions	1.0	null
PPP2R5C	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28795
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179868,GSE180330_1_v_2_ddx21_human	RummaGEO Gene Perturbation Signatures	1.0	null
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-78-MJ16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206196
regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2025	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02095
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36719
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958739
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein ubiquitination	GO Biological Process Annotations 2025	1.0	null
leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.344574
known	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LH-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP107	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8719356-NIHMS1762846-supplement-2.xlsx-cluster_EC2_x_cluster_EC1-ID_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
PGK1	Pathway Commons Protein-Protein Interactions	1.0	null
PREP	Pathway Commons Protein-Protein Interactions	1.0	null
RRN3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.75371
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hcc	GeneRIF Biological Term Annotations	1.0	null
Duckembryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to interferon-gamma	GO Biological Process Annotations 2015	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	1.09538
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	1.63657
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08246
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052908
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.12767
TRMT10C	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM86A	Pathway Commons Protein-Protein Interactions	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.88819
P4HB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
15720813-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neddylation	Reactome Pathways 2024	1.0	null
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LN340	DepMap CRISPR Gene Dependency	1.0	8.31664
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGLN3	Pathway Commons Protein-Protein Interactions	1.0	null
DB	DepMap CRISPR Gene Dependency	1.0	2.42034
FASTKD5	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29457
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946273
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
PML body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.371
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85481
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828813
ZKSCAN1	Pathway Commons Protein-Protein Interactions	1.0	null
EPRS	Pathway Commons Protein-Protein Interactions	1.0	null
protein modification by small protein conjugation	GO Biological Process Annotations 2015	1.0	null
rpn10	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPVG-2026-SM-4B65E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920093
Brain Lower Grade Glioma_LGG_TCGA-HT-7689-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373118
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
hepatoma	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965111
Epithelioma	DisGeNET Gene-Disease Associations	1.0	null
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
EP300	ENCODE Transcription Factor Targets	1.0	null
FGF12	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1145
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
PGBD5	Pathway Commons Protein-Protein Interactions	1.0	null
Postsynaptic endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
FANCL	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of mitotic cell cycle	GO Biological Process Annotations 2025	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67341
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887332
RPL32	Pathway Commons Protein-Protein Interactions	1.0	null
NDUFS2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03659
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.823582
Peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.573
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Heart_GSE4470_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5618
ACTL6A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8402-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fatylation	GeneRIF Biological Term Annotations	1.0	null
UBE2Z	Pathway Commons Protein-Protein Interactions	1.0	null
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
TARDBP	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6761106__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.53699
GSE206870,GSE206872_3_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LUBAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.092
irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.208245
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991525
hydrophobic	GeneRIF Biological Term Annotations	1.0	null
Metastatic Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GSE197342_1_v_0_berberine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
escrt i complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.322325
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214592
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
reports	GeneRIF Biological Term Annotations	1.0	null
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.33471
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88934
CEP72	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of i-kappab kinase/nf-kappab signaling	GO Biological Process Annotations 2015	1.0	null
Perturb_5518_KO_Hdac6_SRP349184	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.59423
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.84198
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	2.73126
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.08517
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873313
TRIM47	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49869
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.060846
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
realtime	GeneRIF Biological Term Annotations	1.0	null
A-498 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
NPLOC4	Pathway Commons Protein-Protein Interactions	1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.335807
namalwa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546136
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1788
Lung squamous cell carcinoma_LUSC_TCGA-18-3417-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP4B1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.836837
GSE186810,GSE186813_3_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PELP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1276
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPIB	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
Celiac Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46613
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15735
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.967767
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.783
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.98449
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
estradiol_homo sapiens_gpl571_gds4052	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25058
BD-50-HU68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363196
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927358
Perturb_4494_KO_Ccr8_SRP293026	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.89311
translation	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8532
chains	GeneRIF Biological Term Annotations	1.0	null
SETDB2	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
diubiquitins	GeneRIF Biological Term Annotations	1.0	null
SNAPC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31098
Focal Glomerulosclerosis	DisGeNET Gene-Disease Associations	1.0	null
g2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5419
localization	GeneRIF Biological Term Annotations	1.0	null
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Field CA2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06656
ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.410259
rainforest	GeneRIF Biological Term Annotations	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.028
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436438
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3313
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
hiv	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46U-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED17	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07512
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF6	Pathway Commons Protein-Protein Interactions	1.0	null
Polycistic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.44572
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11928
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
15642130-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SCF ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.516
myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100588
SUPT16H	Pathway Commons Protein-Protein Interactions	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1397
GCAT	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4566-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNB2	Pathway Commons Protein-Protein Interactions	1.0	null
HMGN3	Pathway Commons Protein-Protein Interactions	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
e1like	GeneRIF Biological Term Annotations	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
NUDT13	Pathway Commons Protein-Protein Interactions	1.0	null
HMGB2	Pathway Commons Protein-Protein Interactions	1.0	null
AAMP	Pathway Commons Protein-Protein Interactions	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
USP16	Pathway Commons Protein-Protein Interactions	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	1.0	1.16896
altered susceptibility to bacterial infection	MPO Gene-Phenotype Associations	1.0	null
ESCRT-0 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
appendix	HPA Tissue Gene Expression Profiles	1.0	0.96544
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.25713
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12553
JUP	Pathway Commons Protein-Protein Interactions	1.0	null
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42972
FBL	Pathway Commons Protein-Protein Interactions	1.0	null
Aggresome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.214
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1269
Site of DNA damage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.331
COIL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891437
pcr	GeneRIF Biological Term Annotations	1.0	null
transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.075435
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051761
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
IkappaB kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98671
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.965388
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.84092
biopsy	GeneRIF Biological Term Annotations	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24494
FCHSD2	Pathway Commons Protein-Protein Interactions	1.0	null
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.62313
Alate adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
RUFY1	Pathway Commons Protein-Protein Interactions	1.0	null
gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298371
vhs	GeneRIF Biological Term Annotations	1.0	null
mutant	GeneRIF Biological Term Annotations	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VC-19-YG34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200251
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
FLOT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	10.0129
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
SULT2A1	Pathway Commons Protein-Protein Interactions	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9749
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041214
NCIH1648	CCLE Cell Line Gene Expression Profiles	1.0	2.12141
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	3.40785
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-NFKB1-HIT_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nasopharyngeal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.023
byrsonima	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66558
hivassociated	GeneRIF Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ubiquitinlike	GeneRIF Biological Term Annotations	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22939
aggresome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
catabolic process	GO Biological Process Annotations 2015	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
C17orf75	Pathway Commons Protein-Protein Interactions	1.0	null
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3455
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.41202
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.591727
plant	GeneRIF Biological Term Annotations	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16082
QTRT1	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC6 interactions in the central nervous system	WikiPathways Pathways 2024	1.0	null
Colorectal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.13621
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68605
cell activation	GO Biological Process Annotations 2015	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16719
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
correlated	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PB-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.229
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.60198
TUBB4A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-LPS_vs_CTR-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50842
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55068
against	GeneRIF Biological Term Annotations	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	2.20796
Abortion, Spontaneous	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perturb_16767_KO_Il6_DRP006148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.6929
KMS20	CCLE Cell Line Gene Expression Profiles	1.0	2.49104
increased apoptosis	MPO Gene-Phenotype Associations	1.0	null
escrt-0 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.724365
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
ORAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
anaphase-promoting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.522
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.84341
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
BYSL	Pathway Commons Protein-Protein Interactions	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950375
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
myeloid leukocyte activation	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34746
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60072
disease	GWASdb SNP-Disease Associations	1.0	0.026652
maximum	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.64313
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
18172295-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96256
hsa-miR-4774-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933662
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953842
KB-3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myeloid dendritic cell activation	GO Biological Process Annotations 2023	1.0	null
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60809
HCT-116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28105
CANT1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876801
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
MTCH2	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-83-5908-01A-21R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA2, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00409
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242363
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
CHST14	Pathway Commons Protein-Protein Interactions	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17953
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963601
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95512
HS742T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90118
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877495
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17681_KO_Kdm4a_SRP101992	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.11473
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2064
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131646
DDX55	Pathway Commons Protein-Protein Interactions	1.0	null
COP9 signalosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.584
Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A61P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proteolysis	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35329
GSE149880_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HT-1376 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
differs	GeneRIF Biological Term Annotations	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.815781
PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IRAK1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12003903-41531_2025_933_MOESM1_ESM.pdf-19-ZNF184_ZNF184	Rummagene Transcription Factor Associations 2026	1.0	null
BBS2	Pathway Commons Protein-Protein Interactions	1.0	null
ERAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8023-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
processes	GeneRIF Biological Term Annotations	1.0	null
colorectal	GeneRIF Biological Term Annotations	1.0	null
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056055
CDC25B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953334
PMC4224449-pone.0112193.s009.xlsx-PPI_MODULES_CLEAN_MAP_merg_OUT-Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
HIF1AN	Pathway Commons Protein-Protein Interactions	1.0	null
MSN	Pathway Commons Protein-Protein Interactions	1.0	null
RQC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC71	Pathway Commons Protein-Protein Interactions	1.0	null
Inclusion body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC6512360__F9	PFOCR Pathway Figure Associations 2024	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	2.41109
GSK3A_knockdown_207_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.2177
Small intestine adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
cullin-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.678
HPAFII	DepMap CRISPR Gene Dependency	1.0	6.23078
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.54839
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63546
bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.532314
Hepatitis, Animal	CTD Gene-Disease Associations	1.0	2.88009
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
LMNB2	Pathway Commons Protein-Protein Interactions	1.0	null
PNGase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
covalently	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14175
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
small thymus	MGI Mouse Phenotype Associations 2023	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8911
OVOL2_01_313	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.98008
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882969
INO80-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905317
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC33A1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
NUP43	Pathway Commons Protein-Protein Interactions	1.0	null
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.023
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27344
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.045047
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100587_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.34626
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416896
RAD51C	Pathway Commons Protein-Protein Interactions	1.0	null
lead	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6E9-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH41	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19793
LIPE_KO_GDS1318_501_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14021
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18247
Hepatitis	CTD Gene-Disease Associations	1.0	1.20097
structure	GeneRIF Biological Term Annotations	1.0	null
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
OTUD6B	Pathway Commons Protein-Protein Interactions	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.030982
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vprinduced	GeneRIF Biological Term Annotations	1.0	null
HK2	Pathway Commons Protein-Protein Interactions	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29974
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
protein ubiquitination	GO Biological Process Annotations 2015	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.632024
USP7	Pathway Commons Protein-Protein Interactions	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.20166
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.3015
multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240148
ANAPC15	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18247
RUVBL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28384
abnormal cell-mediated immunity	MPO Gene-Phenotype Associations	1.0	null
CTNNA1	Pathway Commons Protein-Protein Interactions	1.0	null
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23078
RCC10RGB	CCLE Cell Line Gene Expression Profiles	1.0	1.90353
proteasome binding	GO Molecular Function Annotations 2015	1.0	null
ZCCHC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186810,GSE186813_7_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSD17B12	Pathway Commons Protein-Protein Interactions	1.0	null
instability	GeneRIF Biological Term Annotations	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04828
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41189
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47109
hoxb9	GeneRIF Biological Term Annotations	1.0	null
nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232599
ALDH3A2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TELO2	Pathway Commons Protein-Protein Interactions	1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.67398
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
POLD2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
Liver Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07132
DNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85076
AC-84-QG99_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26509
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7572606__F1	PFOCR Pathway Figure Associations 2023	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.272953
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IPPK	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996795
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13825
Finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.168
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08977
UBE2I	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vas efferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.594064
rpn1s2	GeneRIF Biological Term Annotations	1.0	null
grade	GeneRIF Biological Term Annotations	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HLA-B	Pathway Commons Protein-Protein Interactions	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to tumor necrosis factor	GO Biological Process Annotations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF135	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
SNAPC5	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.5145
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865137
PAPSS2	Pathway Commons Protein-Protein Interactions	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00359
demonstrated	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proteolysis	GO Biological Process Annotations 2023	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09487
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
angular gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06229
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164087_0_v_1_jmjd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24592
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03467
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16368891-Table1	GeneSigDB Published Gene Signatures	1.0	null
eef1a1	GeneRIF Biological Term Annotations	1.0	null
Autophagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.745
Papilloma	CTD Gene-Disease Associations	1.0	1.17235
Cmah_KO_GDS4770_421_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Mammary Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-IRF1-HIT_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
MAEA	Pathway Commons Protein-Protein Interactions	1.0	null
distribution	GeneRIF Biological Term Annotations	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09235
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916507
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I4-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.1822
HSD17B11	Pathway Commons Protein-Protein Interactions	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071003
dock	GeneRIF Biological Term Annotations	1.0	null
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926126
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24479
dendritic cell differentiation	GO Biological Process Annotations 2015	1.0	null
treatment	GeneRIF Biological Term Annotations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A44A-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01856
nuclear ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.233101
Survivin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01545
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059607
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06458
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KANK2	Pathway Commons Protein-Protein Interactions	1.0	null
serine/threonine protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.092017
stat3	GeneRIF Biological Term Annotations	1.0	null
DRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.823
Proteasome activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06143
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08902
hrpn10s5a	GeneRIF Biological Term Annotations	1.0	null
Idiosyncratic drug effect_Hepatic Tissue_GSE2825	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.38314
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230656
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
crassifolia	GeneRIF Biological Term Annotations	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05826
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931412
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19464
OBFC1	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11858
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	1.0	1.12582
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MDH2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF239	Pathway Commons Protein-Protein Interactions	1.0	null
trans	GeneRIF Biological Term Annotations	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19709
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201635
TLE3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.479647
ATP8A2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992809
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.24087
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL29	Pathway Commons Protein-Protein Interactions	1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94341
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
19235837-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051628
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17114
PRKAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal cell death	MPO Gene-Phenotype Associations	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.350452
EMD	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.497015
LRRFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826896
dysfunction	GeneRIF Biological Term Annotations	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09235
Aneuploidy	CTD Gene-Disease Associations	1.0	1.0637
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17904
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13187
presentation	GeneRIF Biological Term Annotations	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13438
CA-68-TC79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.344102
Metaplasia	CTD Gene-Disease Associations	1.0	1.19113
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.43469
V-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.51452
Learning Disorders	CTD Gene-Disease Associations	1.0	1.77531
Eukaryotic translation initiation factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biochemical	GeneRIF Biological Term Annotations	1.0	null
Secondary Biliary Cholangitis	DisGeNET Gene-Disease Associations	1.0	null
monofat10ylated	GeneRIF Biological Term Annotations	1.0	null
western	GeneRIF Biological Term Annotations	1.0	null
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08074
immunohistochemistry	GeneRIF Biological Term Annotations	1.0	null
CEMP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
LGALS3BP	Pathway Commons Protein-Protein Interactions	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13574
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066993
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
p62	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51877
TWIST1_01_252	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08215
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
protein ubiquitination	GO Biological Process Annotations 2023	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.071469
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0986
abortion, spontaneous	GAD Gene-Disease Associations	1.0	null
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11173
ROS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
Otulipenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	8.75024
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Liver cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
PDAP1	Pathway Commons Protein-Protein Interactions	1.0	null
CTR9	Pathway Commons Protein-Protein Interactions	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
METTL3	Pathway Commons Protein-Protein Interactions	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916507
MAGED1	Pathway Commons Protein-Protein Interactions	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6068
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03106
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5
CAL33	DepMap CRISPR Gene Dependency	1.0	2.76132
PMC12486367-Supplementary_Data2.pdf-272-RFX2_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
MTR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859955
each	GeneRIF Biological Term Annotations	1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33234
SLAIN2	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979268
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6158-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PWWP2B	Pathway Commons Protein-Protein Interactions	1.0	null
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914801
16373702-Table1b	GeneSigDB Published Gene Signatures	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.205
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.069
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
Ubiquinone biosynthesis complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.486
C8orf33	Pathway Commons Protein-Protein Interactions	1.0	null
NADSYN1	Pathway Commons Protein-Protein Interactions	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066365
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
uba6	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC6	Pathway Commons Protein-Protein Interactions	1.0	null
DCAF13	Pathway Commons Protein-Protein Interactions	1.0	null
dendritic cell differentiation	GO Biological Process Annotations 2025	1.0	null
RPS9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NC-28-YK77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.453743
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052658
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868096
Cholestasis	CTD Gene-Disease Associations	1.0	1.17959
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.040713
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275444
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
enhances	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUVBL2	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
inclusion body assembly	GO Biological Process Annotations 2015	1.0	null
EXOSC2	Pathway Commons Protein-Protein Interactions	1.0	null
EWSR1_02_122	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.24626
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38466
dominant	GeneRIF Biological Term Annotations	1.0	null
celiac disease;	GAD Gene-Disease Associations	1.0	null
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88507
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3061
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58184
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13825
fat10	GeneRIF Biological Term Annotations	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.444
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07071
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
independent	GeneRIF Biological Term Annotations	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.11741
epithelial	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
lateral orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867375
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10902
SNU1066	CCLE Cell Line Gene Expression Profiles	1.0	2.01184
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8789288-elife-73137-supp2.xlsx-IRF1_vs_Control-Supplementary_file_2_List_of_genes_induced_by_IRF1_ectopic_expression_or_IFNg_treatment_in_A549_cells_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20T-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.50223
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
pocket	GeneRIF Biological Term Annotations	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.2031
Cutaneous lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
Perturb_1428_KO_Adm2_SRP399375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.64373
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35166
15381369-Table2	GeneSigDB Published Gene Signatures	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31919
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
CB-69-KJ83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201784
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.50423
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pulvinus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61975
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
altered susceptibility to infection	MPO Gene-Phenotype Associations	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCLO	Pathway Commons Protein-Protein Interactions	1.0	null
Glandular stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
SNU761	CCLE Cell Line Gene Expression Profiles	1.0	1.53731
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
multivesicular body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.417685
decreased memory-marker CD4-positive NK T cell number	IMPC Knockout Mouse Phenotypes	1.0	null
19318547-Table1	GeneSigDB Published Gene Signatures	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.01773
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846525
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
AE-19-BK71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.720299
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17064
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893331
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.702103
TRIM4	Pathway Commons Protein-Protein Interactions	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061051
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
resolution	GeneRIF Biological Term Annotations	1.0	null
macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377773
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
ESC_V6.5_UP_EARLY.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996319
myocytes	GeneRIF Biological Term Annotations	1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
rna	GeneRIF Biological Term Annotations	1.0	null
GIGYF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07075
MCM3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09676
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885104
ORC5	Pathway Commons Protein-Protein Interactions	1.0	null
proteolysis	GeneRIF Biological Term Annotations	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98764
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44417
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14414
MTMR1	Pathway Commons Protein-Protein Interactions	1.0	null
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205948
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70955
Perturb_10740_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.65574
SNX29	Pathway Commons Protein-Protein Interactions	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	2.37804
AD-82-AM64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219633
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06805
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
Asymmetric Septal Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07956
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40271
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062346
GSE71972_9_v_12_histamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259473
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Post-translational protein modification	Reactome Pathways 2024	1.0	null
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73924
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203158_1_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44242
ANAPC7	Pathway Commons Protein-Protein Interactions	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
environment	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966846
HES4	Pathway Commons Protein-Protein Interactions	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.58444
HIST1H1D	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.90292
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM44	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13782
Promyelocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.12994
Arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.153
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2025	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353027
Hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.167
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
Lung adenocarcinoma_LUAD_TCGA-55-8089-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233441_1_v_0_tnnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.66596
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899566
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.97506
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
HS737T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58009
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreatic	GeneRIF Biological Term Annotations	1.0	null
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.511021
TRIM32	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041235
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085322
Micropyle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.702103
immunohistochemical	GeneRIF Biological Term Annotations	1.0	null
NBPF3	Pathway Commons Protein-Protein Interactions	1.0	null
SRGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.45976
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
extract	GeneRIF Biological Term Annotations	1.0	null
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185872_0_v_2_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
increased susceptibility to infection	MPO Gene-Phenotype Associations	1.0	null
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0987
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03794
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38818
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126776_2_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.51569
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
betacatenintcf4	GeneRIF Biological Term Annotations	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
TERF1	Pathway Commons Protein-Protein Interactions	1.0	null
LS411N	DepMap CRISPR Gene Dependency	1.0	3.66013
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.930237
Trachea-mucus secreting cell	Tabula Sapiens Gene-Cell Associations	1.0	0.00955034
WDR74	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200352_5_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5520_OE_LRG1_SRP386433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.7832
character	GeneRIF Biological Term Annotations	1.0	null
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NACA	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polar nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.946315
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
PPIL3	Pathway Commons Protein-Protein Interactions	1.0	null
t69-brown-adipose_female_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-3.55888
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21239
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-2.49526
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34341
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.59812
myeloid dendritic cell differentiation	GO Biological Process Annotations 2015	1.0	null
HRAS	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Membrane fusion priming complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE185163_5_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.833679
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.82288
regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2023	1.0	null
AAR2	Pathway Commons Protein-Protein Interactions	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.7796
RCHACV	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40539
Unicellular trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862799
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.22821
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LARP1B	Pathway Commons Protein-Protein Interactions	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210774
myeloid cell differentiation	GO Biological Process Annotations 2015	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.26239
still	GeneRIF Biological Term Annotations	1.0	null
aggresome	GO Cellular Component Annotations 2015	1.0	null
PMC7057977__F5	PFOCR Pathway Figure Associations 2024	1.0	null
EBAG9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20506
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
ACTBL2	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPUL1	Pathway Commons Protein-Protein Interactions	1.0	null
small thymus	IMPC Knockout Mouse Phenotypes	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.072
Rad6-Rad18 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
DDX20	Pathway Commons Protein-Protein Interactions	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	2.05833
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
PPIA	Pathway Commons Protein-Protein Interactions	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29803
POR_DELETION_GDS1093_240_mouse_Liver from male 3 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Non-Arthropod Borne Lymphocytic Choriomeningitis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_10926_KO_Lis1_SRP126777	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00728
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35294
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843338
NCDN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal seminal vesicle morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
GTEX-P4QS-0626-SM-3NMD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883083
Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85481
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043354
polycystic	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30069
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.38934
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954876
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.164
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endosomal scaffold complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048671
PMC2768459-6605275x5.xls-Hoja1-Supplementary_Table_S2_Differentially_expressed_genes_within_the_ESR1-negative_BRCA1_tumors_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2C_01_53	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.81893
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344818
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01391
machinery	GeneRIF Biological Term Annotations	1.0	null
PCBP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7868042__F2	PFOCR Pathway Figure Associations 2024	1.0	null
ESCRT III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
sirna	GeneRIF Biological Term Annotations	1.0	null
Perturb_11158_KO_Mdr2_SRP070832	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.18394
CYFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A8BP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
identification	GeneRIF Biological Term Annotations	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85142
Megasporocyte nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
skin	HPA Tissue Protein Expression Profiles	-1.0	-0.713099
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nodes	GeneRIF Biological Term Annotations	1.0	null
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-PITX1-HIT_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
contains	GeneRIF Biological Term Annotations	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.100131
glandular stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.926764
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.09296
DCAF8	Pathway Commons Protein-Protein Interactions	1.0	null
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71698
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
AURKA	Pathway Commons Protein-Protein Interactions	1.0	null
doxorubicin_homo sapiens_gpl96_gse12972	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FANCI	Pathway Commons Protein-Protein Interactions	1.0	null
modification-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376494
Oligospermia	CTD Gene-Disease Associations	1.0	1.3759
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.575383
MYC_Activation - 21 days_GDS2025_727_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arteriosclerosis	CTD Gene-Disease Associations	1.0	1.03159
PMC7471342__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28558
reveal	GeneRIF Biological Term Annotations	1.0	null
reverse	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932838
15793299-TableA	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911415
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
such	GeneRIF Biological Term Annotations	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18433
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10933424-41420_2024_1903_MOESM1_ESM.pdf-2-PRDM13_PRDM13	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic system phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79253
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17667
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L-540 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
invasive	GeneRIF Biological Term Annotations	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48389
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTNNA2	Pathway Commons Protein-Protein Interactions	1.0	null
NUB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112762,GSE112767_1_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21781
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YWHAQ	Pathway Commons Protein-Protein Interactions	1.0	null
increased susceptibility to bacterial infection	MGI Mouse Phenotype Associations 2023	1.0	null
RPS28	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236511_1_v_0_ngfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.34751
burkitt lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111341
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.702103
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861793
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056563
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.229
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.088154
colo824	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
LTBR_INHIBITION - 27 Day_GDS2004_736_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Eczema	DisGeNET Gene-Disease Associations	1.0	null
Liver Cirrhosis, Biliary	CTD Gene-Disease Associations	1.0	2.88009
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34123
circuit	GeneRIF Biological Term Annotations	1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diagnosis	GeneRIF Biological Term Annotations	1.0	null
Glomerulosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836018
17683518-813GeneTable	GeneSigDB Published Gene Signatures	1.0	null
Ubiquitin conjugating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.1437
leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
GALK1	Pathway Commons Protein-Protein Interactions	1.0	null
TAL1_01_152	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59838
Perturb_15133_OE_Klf10_SRP360603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.2351
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28028
motif	GeneRIF Biological Term Annotations	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957957
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54107
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VCP-NPL4-UFD1 AAA ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.655
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.542963
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9699
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81826
CCDC28A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961142
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
proteolysis involved in cellular protein catabolic process	GO Biological Process Annotations 2015	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46175
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissue	GeneRIF Biological Term Annotations	1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPTOR	Pathway Commons Protein-Protein Interactions	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3605
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
transcription	GeneRIF Biological Term Annotations	1.0	null
GCN1L1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEATR3	Pathway Commons Protein-Protein Interactions	1.0	null
proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166167
Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58446
PIP5K1A	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11090_OE_Alr_SRP153001	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
pathways	GeneRIF Biological Term Annotations	1.0	null
QTRTD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRIX1	Pathway Commons Protein-Protein Interactions	1.0	null
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15016
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853625
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
drives	GeneRIF Biological Term Annotations	1.0	null
C17orf85	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12621
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.49407
regulation of i-kappab kinase/nf-kappab signaling	GO Biological Process Annotations 2015	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
GTPBP4	Pathway Commons Protein-Protein Interactions	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
MEF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG13	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834488
nucleus	GO Cellular Component Annotations 2015	1.0	null
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066599
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
Lung Injury	CTD Gene-Disease Associations	1.0	1.62803
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35197
GSE186810,GSE186813_3_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMD6	Pathway Commons Protein-Protein Interactions	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063089
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32135
bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08273
TPM4	Pathway Commons Protein-Protein Interactions	1.0	null
ALDOC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80665
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986941
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01432
Focal segmental glomerulosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
FARSA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
m cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48087
Anophthalmia And Pulmonary Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
Tertiary granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
CBWD1	Pathway Commons Protein-Protein Interactions	1.0	null
TARS	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135378
CALU	Pathway Commons Protein-Protein Interactions	1.0	null
CLIP4	Pathway Commons Protein-Protein Interactions	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50223
RPS20	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
SSX2IP	Pathway Commons Protein-Protein Interactions	1.0	null
mediator	GeneRIF Biological Term Annotations	1.0	null
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.265662
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.93569
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4107
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_8-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046757
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55071
AATF	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CAPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.42613
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.57531
spindleassembly	GeneRIF Biological Term Annotations	1.0	null
adenocarcinoma	GeneRIF Biological Term Annotations	1.0	null
Kir2 inward rectifier potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
GSE135359_0_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.206
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24596
fluorouracil_homo sapiens_gpl550_mcf-7_gds1627	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.4166
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99249
ARMCX3	Pathway Commons Protein-Protein Interactions	1.0	null
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
PSMD7	Pathway Commons Protein-Protein Interactions	1.0	null
response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
HSD17B4_KO_GDS3468_503_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7572606__F1	PFOCR Pathway Figure Associations 2024	1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.26826
Male infertility	WikiPathways Pathways 2024	1.0	null
UBE2M	Pathway Commons Protein-Protein Interactions	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
Perturb_11112_KO_Gmfb_SRP359344	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.84846
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8118
transcriptasepolymerase	GeneRIF Biological Term Annotations	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44312
GaMG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MC-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843534
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
YH13	DepMap CRISPR Gene Dependency	1.0	2.53462
SPRR4	Pathway Commons Protein-Protein Interactions	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2H2	Pathway Commons Protein-Protein Interactions	1.0	null
Optic atrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855078
BHT101	CCLE Cell Line Gene Expression Profiles	1.0	2.5116
PIAS1	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.22
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865936
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC6535783__F1	PFOCR Pathway Figure Associations 2023	1.0	null
induction	GeneRIF Biological Term Annotations	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3035
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.57945
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	7.14433
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48381
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.52889
abbreviated	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
initiate	GeneRIF Biological Term Annotations	1.0	null
ZNF543	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89345
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.35991
MAPKAPK5	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576415
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.83235
Ubiquitin-like	InterPro Predicted Protein Domain Annotations	1.0	null
checkpoint	GeneRIF Biological Term Annotations	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10781639-41586_2023_6618_MOESM4_ESM.xlsx-ST12-Unnamed_5_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
18172295-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
leukocyte activation	GO Biological Process Annotations 2015	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.556
DSG1	Pathway Commons Protein-Protein Interactions	1.0	null
Colorectal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
GSE162276_4_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RABEPK	Pathway Commons Protein-Protein Interactions	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494136
ZNF14	Pathway Commons Protein-Protein Interactions	1.0	null
aggresome	GO Cellular Component Annotations 2025	1.0	null
QA-14-AU91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334442
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178011
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
pairs	GeneRIF Biological Term Annotations	1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDIA3	Pathway Commons Protein-Protein Interactions	1.0	null
DSC1	Pathway Commons Protein-Protein Interactions	1.0	null
Derlin-1 retrotranslocation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
ACADSB	Pathway Commons Protein-Protein Interactions	1.0	null
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
NBR1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8853518-pcbi.1009800.s006.xlsx-M_Fatty_Acid_PPAR-Unnamed_0_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
16373702-Table1a	GeneSigDB Published Gene Signatures	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.96625
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
a95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.702103
SLC25A24	Pathway Commons Protein-Protein Interactions	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
PMC11551338-pnas.2411189121.sd01.xlsx-FXR-Unnamed_0_NR1H4	Rummagene Transcription Factor Associations 2026	1.0	null
ductal	GeneRIF Biological Term Annotations	1.0	null
PSMA4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.79816
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
MCMBP	Pathway Commons Protein-Protein Interactions	1.0	null
DHFR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540585
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_5_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ufm1	GeneRIF Biological Term Annotations	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63775
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.063
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10342
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06603
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
GLIPR2	Pathway Commons Protein-Protein Interactions	1.0	null
H4 neuroglioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
SLC25A4	Pathway Commons Protein-Protein Interactions	1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063084
GSTP1	Pathway Commons Protein-Protein Interactions	1.0	null
u5 snrnp	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.441312
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	1.74478
P2RY4	Pathway Commons Protein-Protein Interactions	1.0	null
polyglutamine	GeneRIF Biological Term Annotations	1.0	null
RPL11	Pathway Commons Protein-Protein Interactions	1.0	null
CAPAN1	CCLE Cell Line Gene Expression Profiles	1.0	1.81264
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.935335
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052241
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.138706
celiac	GeneRIF Biological Term Annotations	1.0	null
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870207
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5888
Lung adenocarcinoma_LUAD_TCGA-44-6145-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
BICR16	DepMap CRISPR Gene Dependency	1.0	2.87933
tn5b14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85635
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01316
LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1-BARD1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842707
Tcf1_KO_GDS1473_307_mouse_Pancreatic islets	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
inferior frontal gyrus, triangular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840666
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
SNB75	DepMap CRISPR Gene Dependency	1.0	2.05492
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31044
doxorubicin_homo sapiens_gpl570_gse11940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.46304
late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.237042
cytokineinduced	GeneRIF Biological Term Annotations	1.0	null
ATXN2L	Pathway Commons Protein-Protein Interactions	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28384
C1orf35	Pathway Commons Protein-Protein Interactions	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38412
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPR153	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837873
NSUN2	Pathway Commons Protein-Protein Interactions	1.0	null
myeloid dendritic cell activation	GO Biological Process Annotations 2015	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351114
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69315
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21224
BRE	Pathway Commons Protein-Protein Interactions	1.0	null
15381369-Table6	GeneSigDB Published Gene Signatures	1.0	null
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
EC-09-DC91_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318804
Atg12-Atg5-Atg16 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950065
FMR1	Pathway Commons Protein-Protein Interactions	1.0	null
degradation	GeneRIF Biological Term Annotations	1.0	null
congenital	GeneRIF Biological Term Annotations	1.0	null
H2AFX	Pathway Commons Protein-Protein Interactions	1.0	null
active	GeneRIF Biological Term Annotations	1.0	null
ATXN10	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.086411
increased apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6889
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03924
BRISC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.35
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Proteasome storage granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
Juvenile leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
ESCRT I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84433
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.32251
substantially	GeneRIF Biological Term Annotations	1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02095
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60689
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.44355
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.601066
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978418
AC-41-MB45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271194
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186460_3_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
TIGD5	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_787_KD_Irf3_SRP074478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.54791
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21239
PMC12714181-pone.0337892.s004.xlsx-Supplementary_Table2-S4_Table_Differential_expressed_genes_between_si-CEBPB_and_si-NC_HCT116_cells_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62595
20081812-Table3	GeneSigDB Published Gene Signatures	1.0	null
Epididymal white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12345
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69036
RH30	DepMap CRISPR Gene Dependency	1.0	2.17308
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93218
Mammary Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
sample	GeneRIF Biological Term Annotations	1.0	null
spleen	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF3	Pathway Commons Protein-Protein Interactions	1.0	null
TSSC1	Pathway Commons Protein-Protein Interactions	1.0	null
FAM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41126
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72358
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10531
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054923
how	GeneRIF Biological Term Annotations	1.0	null
PSME1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.2323
PCNA	Pathway Commons Protein-Protein Interactions	1.0	null
WDTC1	Pathway Commons Protein-Protein Interactions	1.0	null
response to type II interferon	GO Biological Process Annotations 2023	1.0	null
TS-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64028
phase	GeneRIF Biological Term Annotations	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
PSME3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186810,GSE186813_7_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PEX6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52379
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19429
GSE122509,GSE122513_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
NALM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69785
Hypertrophy	CTD Gene-Disease Associations	1.0	1.72446
ENPP2	Pathway Commons Protein-Protein Interactions	1.0	null
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.58154
chain	GeneRIF Biological Term Annotations	1.0	null
CIRH1A	Pathway Commons Protein-Protein Interactions	1.0	null
PRKCSH	Pathway Commons Protein-Protein Interactions	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52226
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13691
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.962063
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.50668
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62065
PSMD4	Pathway Commons Protein-Protein Interactions	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28384
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
node	GeneRIF Biological Term Annotations	1.0	null
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24018
crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173057
KIF20A	Pathway Commons Protein-Protein Interactions	1.0	null
crystal	GeneRIF Biological Term Annotations	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44861
region	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00249
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01545
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55853
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277908
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828641
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69036
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.40401
AE-00-NY23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209612
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995138
LX-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
Mdr2_KO_GDS1990_285_mouse_Livers of 3 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.856755
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
superior parietal lobule, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83075
MTMR6	Pathway Commons Protein-Protein Interactions	1.0	null
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GADD45B	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_18150_KO_Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.4779
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7619
18180321-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
spectrin-associated cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65962
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980014
NCIH2286	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56133
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78P-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
positive regulation of I-kappaB kinase/NF-kappaB signaling	GO Biological Process Annotations 2023	1.0	null
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14641_KO_Lats1/Lats2_SRP189870	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93179
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72397
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917708
GSK3A_knockdown_203_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.64422
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14041
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DDX41	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02944
PMC8047323-Table_2.xlsx-LPS_PMMA_T24-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3152-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2857
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.702103
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.54557
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23716
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899367
tubular	GeneRIF Biological Term Annotations	1.0	null
PMC6535783__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mallorydenk	GeneRIF Biological Term Annotations	1.0	null
MYO1C	Pathway Commons Protein-Protein Interactions	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
reported	GeneRIF Biological Term Annotations	1.0	null
biology	GeneRIF Biological Term Annotations	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
Bladder	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21806
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86617
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839452
Atrophy	CTD Gene-Disease Associations	1.0	1.39646
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04422
COPS7A	Pathway Commons Protein-Protein Interactions	1.0	null
17483295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neurofibromatosis	DisGeNET Gene-Disease Associations	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938123
Lewy body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.199
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50876
PMC7057977__F5	PFOCR Pathway Figure Associations 2023	1.0	null
SUMO2	Pathway Commons Protein-Protein Interactions	1.0	null
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955854
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14736
GTEX-X88G-0226-SM-4GIE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18094
Perturb_16926_KO_Hete_SRP220444	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.51951
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30155
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.28656
NCK2	Pathway Commons Protein-Protein Interactions	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.04034
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56858
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68793
MED23	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
PMC1964512__F3	PFOCR Pathway Figure Associations 2023	1.0	null
15793299-TableC	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26061
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4054
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Galloway-Mowat syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18221
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6068
EIF1AY	Pathway Commons Protein-Protein Interactions	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
basis	GeneRIF Biological Term Annotations	1.0	null
Proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.866
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853625
termed	GeneRIF Biological Term Annotations	1.0	null
HIP1R	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044125
BICR10	DepMap CRISPR Gene Dependency	1.0	4.44568
Influenza A	DisGeNET Gene-Disease Associations	1.0	null
interactions	GeneRIF Biological Term Annotations	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.405582
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.09321
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.353712
TARS2	Pathway Commons Protein-Protein Interactions	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.051914
renal	GeneRIF Biological Term Annotations	1.0	null
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48191
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08274
Hemoglobin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0803
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.86464
EPB41L4A	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34655
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12073
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5817
Perturb_11148_KD_Cx43_ERP124601	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inclusion body assembly	GO Biological Process Annotations 2025	1.0	null
AIPL1	Pathway Commons Protein-Protein Interactions	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64505
GNL3L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.82652
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029863
TBL2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13523
SNU46	DepMap CRISPR Gene Dependency	1.0	4.44107
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A1	Pathway Commons Protein-Protein Interactions	1.0	null
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
bodies	GeneRIF Biological Term Annotations	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hdac6	GeneRIF Biological Term Annotations	1.0	null
RPL39L	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213632_0_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG	Pathway Commons Protein-Protein Interactions	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	3.12078
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00071
Allergic Symptom	DisGeNET Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94637
Perturb_12085_OE_Cyp19a1_SRP050547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.70105
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6607389__F3	PFOCR Pathway Figure Associations 2024	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.274378
FOXRED2	Pathway Commons Protein-Protein Interactions	1.0	null
bind	GeneRIF Biological Term Annotations	1.0	null
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090417
NOL7	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980921
GPN3	Pathway Commons Protein-Protein Interactions	1.0	null
appendices_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07513
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26594
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to organonitrogen compound	GO Biological Process Annotations 2015	1.0	null
CYR61	Pathway Commons Protein-Protein Interactions	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.32905
affinities	GeneRIF Biological Term Annotations	1.0	null
SARS-BatSRBD_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65644
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09095
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL30	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7435
JUN	ENCODE Transcription Factor Targets	1.0	null
abnormal lymphocyte physiology	MPO Gene-Phenotype Associations	1.0	null
A-2058 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
lysines	GeneRIF Biological Term Annotations	1.0	null
processing	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03805
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51938
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905046
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
ECD	Pathway Commons Protein-Protein Interactions	1.0	null
tissues	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09049
SNAP47	Pathway Commons Protein-Protein Interactions	1.0	null
tnfalpha	GeneRIF Biological Term Annotations	1.0	null
positive regulation of programmed cell death	GO Biological Process Annotations 2025	1.0	null
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.035
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
cold-induced sweating syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Pons, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05447
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00857
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.85468
Pancreatic adenocarcinoma_PAAD_TCGA-M8-A5N4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metastasis	GeneRIF Biological Term Annotations	1.0	null
Mdr2_KO_GDS1990_286_mouse_Livers of 12 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
irinotecan_rattus norvegicus_gpl1355_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987979
ikappab kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.356705
UBC	Hub Proteins Protein-Protein Interactions	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22133
Huntington Disease	DisGeNET Gene-Disease Associations	1.0	null
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
CLNS1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.44778
ASB6	Pathway Commons Protein-Protein Interactions	1.0	null
ALB	Pathway Commons Protein-Protein Interactions	1.0	null
AD-66-NV75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32962
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6314
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
longer	GeneRIF Biological Term Annotations	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29466
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sites	GeneRIF Biological Term Annotations	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995139
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19253
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPC24	Pathway Commons Protein-Protein Interactions	1.0	null
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221831
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
HAUS5	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3924-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14794
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
after	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trachea-t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.00955034
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01469
GSE101546_2_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2303
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RANBP10	Pathway Commons Protein-Protein Interactions	1.0	null
decreased memory-marker CD4-positive NK T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62527
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOLLIP	Pathway Commons Protein-Protein Interactions	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	0.702103
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.12048
BACH1	ChEA Transcription Factor Targets	1.0	null
PMC7444072__F5	PFOCR Pathway Figure Associations 2024	1.0	null
VCL	Pathway Commons Protein-Protein Interactions	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01162
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
provide	GeneRIF Biological Term Annotations	1.0	null
ED-79-EW79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300752
perilemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00857
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
bound	GeneRIF Biological Term Annotations	1.0	null
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4591983__F5	PFOCR Pathway Figure Associations 2024	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.231409
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6685
DENND6B	Pathway Commons Protein-Protein Interactions	1.0	null
ENO1	Pathway Commons Protein-Protein Interactions	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869158
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2556
PAAF1	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	1.98588
LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970797
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77097
SKRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.37374
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.511021
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.443
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic Ductal Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
PFDN2	Pathway Commons Protein-Protein Interactions	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKP2	Pathway Commons Protein-Protein Interactions	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169091
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
response to tumor necrosis factor	GO Biological Process Annotations 2025	1.0	null
NOL11	Pathway Commons Protein-Protein Interactions	1.0	null
WDR46	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
intestinal	GeneRIF Biological Term Annotations	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.31852
Machado-Joseph disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847449
NCIH1651	CCLE Cell Line Gene Expression Profiles	1.0	1.44543
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUFY2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreas-pancreatic ductal cell	Tabula Sapiens Gene-Cell Associations	1.0	6.3479
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09475
b-lymphoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193717
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69016
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.46889
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985903
Respiratory Hypersensitivity	CTD Gene-Disease Associations	1.0	1.14816
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28558
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19368
PPARA_KO_GDS2886_484_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.96264
HS766T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.21575
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
PES1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4735693-ncomms10380-s2.xlsx-Sheet1-Supplementary_Data_1_BESC_and_GSC_gene_signature_131_genes_2_5_fold_and_p_0_001_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.549773
Perturb_10940_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.1871
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839677
GSE221539_1_v_0_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.859679
DHX38	Pathway Commons Protein-Protein Interactions	1.0	null
fat10specific	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	9.6684
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.3793
interstitial cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.403064
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Johanson-Blizzard syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
CB-01-MR53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.578916
FLOT1	Pathway Commons Protein-Protein Interactions	1.0	null
tumorigenesis	GeneRIF Biological Term Annotations	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05139
NOP16	Pathway Commons Protein-Protein Interactions	1.0	null
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
b-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19033
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960945
DUSP1_KO_GDS1606_775_mouse_Spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CTTN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_12_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
treated	GeneRIF Biological Term Annotations	1.0	null
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18176
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183571
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909754
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-SOX2-Unnamed_6_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal blood cell physiology	MPO Gene-Phenotype Associations	1.0	null
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.229
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15663
DNASE2B	Pathway Commons Protein-Protein Interactions	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.06
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56029
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.702103
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.382
17429429-Table3	GeneSigDB Published Gene Signatures	1.0	null
VRK1	Pathway Commons Protein-Protein Interactions	1.0	null
confirmed	GeneRIF Biological Term Annotations	1.0	null
DEXI	Pathway Commons Protein-Protein Interactions	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
plasma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137716
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
SIRT1_KO_GDS4895_410_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RP58	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.56201
EXOSC10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
response to type II interferon	GO Biological Process Annotations 2025	1.0	null
Nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein modification by small protein conjugation	GO Biological Process Annotations 2025	1.0	null
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162384_1_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0838
NR4A1	Pathway Commons Protein-Protein Interactions	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FAM83H	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11579
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893331
structural	GeneRIF Biological Term Annotations	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404797
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09977
ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391176
uban	GeneRIF Biological Term Annotations	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	8.0178
RPS3A	Pathway Commons Protein-Protein Interactions	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.783
polymorphism	GeneRIF Biological Term Annotations	1.0	null
Skin Diseases	CTD Gene-Disease Associations	1.0	1.08372
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSBPL8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03622
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
SF3A3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216538_7_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.26298
Adenoma	CTD Gene-Disease Associations	1.0	1.43266
aspects	GeneRIF Biological Term Annotations	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.02287
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64447
Malaria	DisGeNET Gene-Disease Associations	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047729
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
MMS19	Pathway Commons Protein-Protein Interactions	1.0	null
SND1	Pathway Commons Protein-Protein Interactions	1.0	null
involving	GeneRIF Biological Term Annotations	1.0	null
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03887
DSTN	Pathway Commons Protein-Protein Interactions	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52878
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
becomes	GeneRIF Biological Term Annotations	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48691
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2516
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTBP2	Pathway Commons Protein-Protein Interactions	1.0	null
leber	GeneRIF Biological Term Annotations	1.0	null
SRPR	Pathway Commons Protein-Protein Interactions	1.0	null
doxorubicin_homo sapiens_gpl96_gds3514	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-large_int_SM-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
TTF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23117
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48727
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2044_KO_Srf_SRP038094	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.09737
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_1006_KO_Bcl9l/Bcl9_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.59051
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13554
mad2	GeneRIF Biological Term Annotations	1.0	null
PSMG1	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931465
Perturb_3298_KO_E8I_SRP144318	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931298
assembly	GeneRIF Biological Term Annotations	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1987
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40366
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.194045
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APMAP	Pathway Commons Protein-Protein Interactions	1.0	null
GB-37-WI36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218988
inducing	GeneRIF Biological Term Annotations	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905317
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2875
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.65775
Neoplasms	CTD Gene-Disease Associations	1.0	2.05382
DUX3	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal thymus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BNC1_KD_GDS1978_70_mouse_oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lubac complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16901
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53416
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Embryo Loss	CTD Gene-Disease Associations	1.0	1.03567
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.25899
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3879
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53495
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.39866
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.935335
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
p53	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10687
hsa-miR-4797-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NSUN5	Pathway Commons Protein-Protein Interactions	1.0	null
DNAJC10	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-354 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18435
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
hypothetical	GeneRIF Biological Term Annotations	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78711
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.85344
cardiac	GeneRIF Biological Term Annotations	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01364
Proteinuria	CTD Gene-Disease Associations	1.0	1.50524
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
RFTN1	Pathway Commons Protein-Protein Interactions	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.82691
VCP-NSFL1C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.979
Bronchioalveolar carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
e225k	GeneRIF Biological Term Annotations	1.0	null
PMC3836475__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.038027
TP63_01_325	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.28602
dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050683
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
Hpv Positive Oropharyngeal Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00409
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
single-organism process	GO Biological Process Annotations 2015	1.0	null
NUP155	Pathway Commons Protein-Protein Interactions	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
EE-08-SZ54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.429645
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960858
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106767
TP53_01_286	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.63619
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
GBE1	Pathway Commons Protein-Protein Interactions	1.0	null
k48linked	GeneRIF Biological Term Annotations	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.4218
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879257
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17201
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33884
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01545
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906246
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52592
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046912
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_REPRESSED-RING1B_EWSR1-FLI1_repressed_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317545
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219264
ten	GeneRIF Biological Term Annotations	1.0	null
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107866
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.35169
LTBR_INHIBITION - 35 Day_GDS2004_737_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20258
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
EHHADH	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14952_OE_Tnfsf14_SRP148550	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
WDR26	Pathway Commons Protein-Protein Interactions	1.0	null
HEPA 1-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
specificity	GeneRIF Biological Term Annotations	1.0	null
18310659-TableS2	GeneSigDB Published Gene Signatures	1.0	null
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84073
NPPB	Pathway Commons Protein-Protein Interactions	1.0	null
act	GeneRIF Biological Term Annotations	1.0	null
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
FBXL18	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4530868-pone.0135339.s005.xls-MI-specific_miRNA-TF_network-Molecule_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aggresome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1718
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17152
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15087
H2AFY	Pathway Commons Protein-Protein Interactions	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074522
Mammary Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.11081
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10897_KO_Nr5a2_SRP131036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82184
pg13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
amaurosis	GeneRIF Biological Term Annotations	1.0	null
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
alzheimer's disease	GAD Gene-Disease Associations	1.0	null
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15349
macromolecular	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5005
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11609
protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.062539
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	1.34504
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V6-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	2.10807
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.172
Phagophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.383
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78013
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041529
proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.250389
MJ	CCLE Cell Line Gene Expression Profiles	1.0	2.12515
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FKBP4	Pathway Commons Protein-Protein Interactions	1.0	null
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49058
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367129
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4093
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3699
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aggresome	GO Cellular Component Annotations 2023	1.0	null
GSE126504_0_v_1_hpse_human	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20742
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14908
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19494
LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ACTR2	Pathway Commons Protein-Protein Interactions	1.0	null
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05899
sirolimus_rattus norvegicus_gpl6247_gse35048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62068
Hyper Ldl Cholesterolaemia	DisGeNET Gene-Disease Associations	1.0	null
16373702-Table3	GeneSigDB Published Gene Signatures	1.0	null
RPL12	Pathway Commons Protein-Protein Interactions	1.0	null
Irritable Bowel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.21141
GSE213632_4_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09672
mediated	GeneRIF Biological Term Annotations	1.0	null
THAP11	Pathway Commons Protein-Protein Interactions	1.0	null
brca1-bard1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.550186
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNG1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82478
diverse	GeneRIF Biological Term Annotations	1.0	null
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07324
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860252
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137914_2_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
deregulation	GeneRIF Biological Term Annotations	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TPI1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908227
CFPAC1	CCLE Cell Line Gene Expression Profiles	1.0	1.44661
GSE223008_9_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertriglyceridemia	CTD Gene-Disease Associations	1.0	1.13862
synergistically	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
enters	GeneRIF Biological Term Annotations	1.0	null
increased CD4-positive, CD25-positive NK T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
GSE233256_0_v_1_rbms1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
osteogenesis imperfecta	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.284013
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.425
MTHFD1	Pathway Commons Protein-Protein Interactions	1.0	null
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53475
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX39B	Pathway Commons Protein-Protein Interactions	1.0	null
blot	GeneRIF Biological Term Annotations	1.0	null
PMC11094182-41408_2024_1061_MOESM18_ESM.xlsx-S17_TP53_genes_signatures-Supplementary_Table_S17_Reported_TP53_target_genes_and_gene_signatures_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_Deficiency_GDS4856_318_mouse_Soleus skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MSL3	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal hematopoietic system physiology	MPO Gene-Phenotype Associations	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.702103
VCY	Pathway Commons Protein-Protein Interactions	1.0	null
whereas	GeneRIF Biological Term Annotations	1.0	null
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MGRN1	Pathway Commons Protein-Protein Interactions	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.940171
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.965524
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
CCNB3	Pathway Commons Protein-Protein Interactions	1.0	null
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.60398
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
PSMB4	Pathway Commons Protein-Protein Interactions	1.0	null
Grb2-EGFR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01654
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15444
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.956314
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.533861
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.9504
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4640-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.762
FAM120B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE63857_3_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26087
immune system process	GO Biological Process Annotations 2015	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058273
XP-V XP30RO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
PMC11961801-12672_2025_2262_MOESM2_ESM.xlsx-Sheet_1-WGCNA_AND_DEGs_NOT_CSGs_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.117567
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62917
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31498
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.62736
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58947
SET	Pathway Commons Protein-Protein Interactions	1.0	null
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.569941
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35982
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.667215
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36912
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854024
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02328
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.05126
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
proinflammatory	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.63743
GSE233566_1_v_2_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIF1A_01_156	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.61784
EIF3C	Pathway Commons Protein-Protein Interactions	1.0	null
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
SNU478	CCLE Cell Line Gene Expression Profiles	1.0	1.817
regulation of cell cycle phase transition	GO Biological Process Annotations 2023	1.0	null
CAV3_KO_GDS3533_17_mouse_mammary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
TGIF2LY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75684
VCPIP1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35182
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP17L1P	Pathway Commons Protein-Protein Interactions	1.0	null
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.919978
Diabetes Mellitus, Type 1	HuGE Navigator Gene-Phenotype Associations	1.0	null
Ripoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572418
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16072
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67129
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	1.47926
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01075
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36924
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Acute Myeloid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
accelerates	GeneRIF Biological Term Annotations	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8456
PMC1964512__F3	PFOCR Pathway Figure Associations 2024	1.0	null
targets	GeneRIF Biological Term Annotations	1.0	null
HARS	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957831
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
enzyme	GeneRIF Biological Term Annotations	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
MAPKAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56702
TMEM252	Pathway Commons Protein-Protein Interactions	1.0	null
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
GSE183890_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GP5D	DepMap CRISPR Gene Dependency	1.0	3.40073
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835756
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10733_OE_Sirt6_SRP282071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.2218
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22511
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
UBLC1	CCLE Cell Line Gene Expression Profiles	1.0	1.59073
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899284
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.218
HIST1H1C	Pathway Commons Protein-Protein Interactions	1.0	null
TERT	Pathway Commons Protein-Protein Interactions	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3541
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
IFFO1	Pathway Commons Protein-Protein Interactions	1.0	null
RNPEP	Pathway Commons Protein-Protein Interactions	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3891
RRM2	Pathway Commons Protein-Protein Interactions	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.66502
GSE186460_0_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5114
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15349
CHMP3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSL4	Pathway Commons Protein-Protein Interactions	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89715
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36075
ATG14	Pathway Commons Protein-Protein Interactions	1.0	null
moiety	GeneRIF Biological Term Annotations	1.0	null
HEL	DepMap CRISPR Gene Dependency	1.0	2.18521
KHOS-240S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2233
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3419
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042303
TXN	Pathway Commons Protein-Protein Interactions	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.783
Hemorrhage	CTD Gene-Disease Associations	1.0	1.04721
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25125
DPH1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8048-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5686-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.82185
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71573
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35536
Inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.953
IGBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17816
genetic	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99383
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.55229
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11404
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.08334
modification-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
TRIM21	Pathway Commons Protein-Protein Interactions	1.0	null
MYL12B	Pathway Commons Protein-Protein Interactions	1.0	null
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
qualifies	GeneRIF Biological Term Annotations	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
b-lymphoblastoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193717
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905355
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040875
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7633
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47324
PL4	DepMap CRISPR Gene Dependency	1.0	13.9713
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
ursodeoxycholic acid_mus musculus_gpl6246_gse22608	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.064
inclusion body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TP53	Pathway Commons Protein-Protein Interactions	1.0	null
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
RPS15A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prometaphase	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
TGFBR1	Hub Proteins Protein-Protein Interactions	1.0	null
cytosolic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061812
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21344
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
DDX39A	Pathway Commons Protein-Protein Interactions	1.0	null
DNA polymerase III, clamp loader complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
staging	GeneRIF Biological Term Annotations	1.0	null
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Human - Fetal Development - L2 - Pancreas-Lymphatic endothelial cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAG6	Pathway Commons Protein-Protein Interactions	1.0	null
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2661
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-1.33525
SOX17_01_300	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60544
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02945
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99104
NUP160	Pathway Commons Protein-Protein Interactions	1.0	null
jy cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.823175
Nuclear SCF ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
GSE246053_4_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
t69-brown-adipose_female_1w	MoTrPAC Rat Endurance Exercise Training	-1.0	-4.73355
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16373702-Table2a	GeneSigDB Published Gene Signatures	1.0	null
interferon	GeneRIF Biological Term Annotations	1.0	null
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.568
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47257
PPARG-19300518-CHIP-PET-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
impaired contextual conditioning behavior	IMPC Knockout Mouse Phenotypes	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7515
stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214636
GSE209928_0_v_1_kmt2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
response to cytokine	GO Biological Process Annotations 2015	1.0	null
TTC21B	Pathway Commons Protein-Protein Interactions	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995198
TP63_01_328	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.28602
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
linear	GeneRIF Biological Term Annotations	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POR_KO_GDS1678_763_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23561
metastatic	GeneRIF Biological Term Annotations	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02303
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6511-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32476
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4969
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
Lung adenocarcinoma_LUAD_TCGA-86-6851-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFCAB5	Pathway Commons Protein-Protein Interactions	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Perturb_11869_KO_Rb1_SRP062249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38041
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98914
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47032
aggresome assembly	GO Biological Process Annotations 2023	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19355
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09642
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.46582
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03509
modified	GeneRIF Biological Term Annotations	1.0	null
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13582
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.89374
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.48782
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
liver	GeneRIF Biological Term Annotations	1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11106_KO_Wtap_SRP310501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04039
SIRT1_KO_GSE28790_47_mouse_brain (3 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.569
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879266
Fatty Liver	CTD Gene-Disease Associations	1.0	2.01376
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nfkappab	GeneRIF Biological Term Annotations	1.0	null
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Premature Birth	CTD Gene-Disease Associations	1.0	1.24997
TUBGCP4	Pathway Commons Protein-Protein Interactions	1.0	null
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03342
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.37275
use1	GeneRIF Biological Term Annotations	1.0	null
dendritic cell differentiation	GO Biological Process Annotations 2023	1.0	null
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.125118
Proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.813
Testicular Diseases	CTD Gene-Disease Associations	1.0	1.07376
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61595
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.4958
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRPK2	Pathway Commons Protein-Protein Interactions	1.0	null
nemo	GeneRIF Biological Term Annotations	1.0	null
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.783
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.378
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37608
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
GSE102870_5_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
Stem cell_Liver_Human	CellMarker Gene-Cell Type Associations	1.0	null
TSG101	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28957
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833429
different	GeneRIF Biological Term Annotations	1.0	null
T173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47915
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
cd95 death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.444482
response to chemical	GO Biological Process Annotations 2015	1.0	null
PABPC1L	Pathway Commons Protein-Protein Interactions	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4308
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34071
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5577301-in-17-237-s002.xls-AR_up_signature-AR_up-regulated_signature_genes_53_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NME7	Pathway Commons Protein-Protein Interactions	1.0	null
AA-98-HX85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209106
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46772
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.079903
GSE127916_1_v_2_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8789288-elife-73137-supp3.xlsx-Gene_List_Comparisons_Top_100-IRF1_-_IFNg_Shared_Unique_from_ISG_Screen_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042366
PNP	Pathway Commons Protein-Protein Interactions	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1659
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein modification by small protein conjugation	GO Biological Process Annotations 2023	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949218
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1	JASPAR Predicted Transcription Factor Targets	1.0	null
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
17429429-Table4	GeneSigDB Published Gene Signatures	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.06073
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27083
POR	Pathway Commons Protein-Protein Interactions	1.0	null
therapeutical	GeneRIF Biological Term Annotations	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.702103
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatitis	DisGeNET Gene-Disease Associations	1.0	null
MAP2	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal lymphocyte physiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.426711
promising	GeneRIF Biological Term Annotations	1.0	null
VARS	Pathway Commons Protein-Protein Interactions	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044598
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.50528
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.82037
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.7542
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08362
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580417
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO45	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD8	Pathway Commons Protein-Protein Interactions	1.0	null
INTS3	Pathway Commons Protein-Protein Interactions	1.0	null
DM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84314
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826004
IFT52	Pathway Commons Protein-Protein Interactions	1.0	null
positive regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
ACSL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1013
Perturb_10910_KO_Thbs1_SRP276889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.07514
Ubiquitin	InterPro Predicted Protein Domain Annotations	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1853
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864876
CB-07-WI76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254654
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCMF1	Pathway Commons Protein-Protein Interactions	1.0	null
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1297
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83918
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fat10overexpressing	GeneRIF Biological Term Annotations	1.0	null
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
overexpression	GeneRIF Biological Term Annotations	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312827
TRIM56	Pathway Commons Protein-Protein Interactions	1.0	null
modification-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11353
Glioma	DisGeNET Gene-Disease Associations	1.0	null
TBC1D15	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43488
Salmonellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
transcriptional	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myeloid leukocyte differentiation	GO Biological Process Annotations 2025	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062927
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
Ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
adenovirusdelivered	GeneRIF Biological Term Annotations	1.0	null
C12orf45	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-11A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
being	GeneRIF Biological Term Annotations	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0172
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99068
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14104
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853517
IER2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2476
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pedal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05013
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05826
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44939
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C3A	CCLE Cell Line Gene Expression Profiles	1.0	1.63432
snps	GeneRIF Biological Term Annotations	1.0	null
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054252
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELOF1	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31044
formation	GeneRIF Biological Term Annotations	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33411
UBA6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6475113__F5	PFOCR Pathway Figure Associations 2023	1.0	null
ubl	GeneRIF Biological Term Annotations	1.0	null
Epithelial cell_Colon_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
antigen	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-468	COSMIC Cell Line Gene Mutation Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.702103
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL38	Pathway Commons Protein-Protein Interactions	1.0	null
AGPAT1	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
WD-15-WN01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328032
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905317
critical	GeneRIF Biological Term Annotations	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.063
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
TTLL7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04545
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20957
myeloid leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
abnormal adaptive immunity	MPO Gene-Phenotype Associations	1.0	null
ubd	GeneRIF Biological Term Annotations	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.21575
inclusion body assembly	GO Biological Process Annotations 2023	1.0	null
Perturb_11094_KO_Regnase1_DRP004811	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4479
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91752
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46754
FAM71C	Pathway Commons Protein-Protein Interactions	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.240479
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72146
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998334
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
when	GeneRIF Biological Term Annotations	1.0	null
increased susceptibility to bacterial infection	MPO Gene-Phenotype Associations	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7489
therapeutic	GeneRIF Biological Term Annotations	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74473
pdac	GeneRIF Biological Term Annotations	1.0	null
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11166
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8047323-Table_1.xlsx-FC_LPS_T24_Vs_LPS_T0_P_0_05_FC-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
brisc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.79148
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hrd1p ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393374
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14169
FAR2	Pathway Commons Protein-Protein Interactions	1.0	null
cancers	GeneRIF Biological Term Annotations	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
MB-32-LQ97_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256871
15914563-Table1	GeneSigDB Published Gene Signatures	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43949
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02306
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863134
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lymph	GeneRIF Biological Term Annotations	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04662
Fibrillar center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
STRAP	Pathway Commons Protein-Protein Interactions	1.0	null
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Kidney_GDS724_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.991509
A-CA-04-2009(H1N1)_24Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31682
Multiple Sclerosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73367
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4304
downregulation	GeneRIF Biological Term Annotations	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.06753
abnormal apoptosis	MPO Gene-Phenotype Associations	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4917
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.11177
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1299
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17133
EIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
C7orf49	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20761
kidney	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924255
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15101
RPS27	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal response to infection	MPO Gene-Phenotype Associations	1.0	null
ARID5A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT1_Deficiency_GDS4895_316_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02389
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178011
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37069
escrt complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.155791
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12837
GSE197342_2_v_0_berberine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.04721
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162276_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CORO1C	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protects	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autophagosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.38441
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
overexpressed	GeneRIF Biological Term Annotations	1.0	null
isotretinoin_homo sapiens_gpl8300_gds3215	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25352
ZNF566	Pathway Commons Protein-Protein Interactions	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
DE-23-IF54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24449
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.35676
MOCS3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10709142-41556_2023_1281_MOESM2_ESM.xlsx-Supplementary_Table_1-CLUSTER_1_MAF_upregulated_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.99479
PIN4	Pathway Commons Protein-Protein Interactions	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUBA1B	Pathway Commons Protein-Protein Interactions	1.0	null
myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109504
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088176
ZNF709	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
response to cytokine	GO Biological Process Annotations 2023	1.0	null
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
folding	GeneRIF Biological Term Annotations	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4957
MAP3K7	Pathway Commons Protein-Protein Interactions	1.0	null
small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.088623
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22972
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913675
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10720_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.85896
Nuclear pore outer ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930108
Liver Diseases	CTD Gene-Disease Associations	1.0	2.13261
Ubiquitin-related domain	InterPro Predicted Protein Domain Annotations	1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.935335
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
according	GeneRIF Biological Term Annotations	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.836
PMC6761106__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_15135_KO_Foxa2_SRP102936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30432
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00369
ATP5A1	Pathway Commons Protein-Protein Interactions	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.293
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11089_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.91272
nucleus	GO Cellular Component Annotations 2025	1.0	null
urinary bladder	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
TMEM126A	Pathway Commons Protein-Protein Interactions	1.0	null
aggresome assembly	GO Biological Process Annotations 2025	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26328
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.86195
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.783
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944856
EBNA1BP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3648157__F7	PFOCR Pathway Figure Associations 2024	1.0	null
GSE158197_2_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.61
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24717
prognostic	GeneRIF Biological Term Annotations	1.0	null
C9orf9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223008_6_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endopeptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.598
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72833
Celiac Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190076_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4869-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834594
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333396
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.65266
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7825
prosurvival	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5630-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COG6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
abnormal leukocyte physiology	MPO Gene-Phenotype Associations	1.0	null
MEN1	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1488
KANSL2	Pathway Commons Protein-Protein Interactions	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.766954
DNAJC8	Pathway Commons Protein-Protein Interactions	1.0	null
DUBm complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.023
JARID2	ChEA Transcription Factor Targets	1.0	null
aggresome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446862
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LB-14-EI63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204093
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906433
NF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSK3A_KD_GDS4305_178_human_HL-60 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.651298
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_7-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
nephropathy	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837802
NCIH841	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84266
UBC13-UEV1A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
various	GeneRIF Biological Term Annotations	1.0	null
Transforming growth factor beta activated kinase 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
Biliary Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.028
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6917-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM27	Pathway Commons Protein-Protein Interactions	1.0	null
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078833
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
conjugation	GeneRIF Biological Term Annotations	1.0	null
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051529
impaired contextual conditioning behavior	MGI Mouse Phenotype Associations 2023	1.0	null
MAGED2	Pathway Commons Protein-Protein Interactions	1.0	null
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AP3M1	Pathway Commons Protein-Protein Interactions	1.0	null
Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
GCDH	Pathway Commons Protein-Protein Interactions	1.0	null
subunits	GeneRIF Biological Term Annotations	1.0	null
DCD	Pathway Commons Protein-Protein Interactions	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.392
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32826
regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058867
MTA2	Pathway Commons Protein-Protein Interactions	1.0	null
BIN67	DepMap CRISPR Gene Dependency	1.0	2.47573
NR5A2_01_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.99858
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15349
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
response to cytokine	GO Biological Process Annotations 2025	1.0	null
PMC6512360__F9	PFOCR Pathway Figure Associations 2023	1.0	null
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	2.24027
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5417
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81913
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4356
GLUL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of canonical NF-kappaB signal transduction	GO Biological Process Annotations 2025	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0313
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.00676
kinetochore	GeneRIF Biological Term Annotations	1.0	null
PMC7471342__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.019
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61803
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916507
SART3	Pathway Commons Protein-Protein Interactions	1.0	null
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23008
DDX3Y	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF-32-FY02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.411201
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08199
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87448
Poisoning	CTD Gene-Disease Associations	1.0	1.3639
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.54694
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
ZNF326	Pathway Commons Protein-Protein Interactions	1.0	null
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of mitotic cell cycle	GO Biological Process Annotations 2023	1.0	null
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920125
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38305
lys48linked	GeneRIF Biological Term Annotations	1.0	null
dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437972
ESCRT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.76
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04198
KA-71-CQ25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247831
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.366
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2117
suggests	GeneRIF Biological Term Annotations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.02151
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861419
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93812
FAM83D	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947432
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
precentral gyrus, left, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09256
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
PC3	DepMap CRISPR Gene Dependency	1.0	3.07688
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10017
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09395
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922612
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05283
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Secretory cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.15895
STAG2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALAD	Pathway Commons Protein-Protein Interactions	1.0	null
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
PMC5866017__F6	PFOCR Pathway Figure Associations 2023	1.0	null
IPO11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24673
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.370368
JF-79-OI50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238868
FOS_01_99	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.29109
MDM2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null