association	dataset	threshold value	standardized value
2-Methoxy-estradiol-17beta 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72058
increased vertical activity	MGI Mouse Phenotype Associations 2023	1.0	null
Octanoylglucuronide	HMDB Metabolites of Enzymes	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17891
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38055
metabolism	GeneRIF Biological Term Annotations	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6485
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01002
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26965
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9205
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93334
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.50191
HEY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.06309
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94422
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36858
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1143
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84681
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.20606
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
HDMYZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74905
SNU1033	DepMap CRISPR Gene Dependency	1.0	5.44832
nasal	GeneRIF Biological Term Annotations	1.0	null
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78949
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03755
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68075
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08106
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8248
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.075
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68423
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07175
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50973
PMC8299217-mmc4.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29191
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846648
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63468
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HD-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.24392
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47949
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57225
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
pattern	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863916
2-Methoxy-estradiol-17b 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02812
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14335
Lithocholate 3-O-glucuronide	HMDB Metabolites of Enzymes	1.0	null
PMC11694450-Table_1.xlsx-MR_to_MM_at_2_DPI-Supplementary_Table_1_1_Differentially_expressed_genes_in_the_cecal_tonsil_transcriptome_in_the_M_R_group_compared_to_the_M_M_group_at_2_DPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
GYPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32851
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81802
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
Mouth floor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44599
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22437
SESN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93288
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4764
SEM	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13453
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.87284
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27878
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OC314	DepMap CRISPR Gene Dependency	1.0	2.33457
endoplasmic reticulum	LOCATE Curated Protein Localization Annotations	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059264
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33636
Defective UGT1A1 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47187
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.96187
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5442
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059755
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33103
Crigler-Najjar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39034
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399871
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72621
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.056
UDP-glycosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32849
2-Methoxyestrone	MW Enzyme Metabolite Associations	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24503
Glucuronidation	Reactome Pathways 2014	1.0	null
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967264
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33382
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73739
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865695
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03336
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.130097
16-alpha,17-beta-estriol 17-beta-D-glucuronide	HMDB Metabolites of Enzymes	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1467
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5644
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE-9	GDSC Cell Line Gene Expression Profiles	1.0	1.57571
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32877
mantle zone of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10202
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4728
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854219
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33373
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0503
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0569
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00739
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863798
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.49126
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05464
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.4559
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Vitamin D2 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80077
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19076
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5807
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69236
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65669
glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459145
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Steroid hormone biosynthesis	KEGG Pathways 2026	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.657989
hsa-miR-2053	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68016
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.93
HCC1569	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07504
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76194
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.4871
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29919
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956547
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.6051
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	1.86136
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9311
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051031
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38461
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45181
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835277
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9118
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14989
Uridine diphosphate glucuronic acid	HMDB Metabolites of Enzymes	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61706
DIFI	DepMap CRISPR Gene Dependency	1.0	3.55984
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063498
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354084
PL4	DepMap CRISPR Gene Dependency	1.0	7.8608
UACC893	DepMap CRISPR Gene Dependency	1.0	10.2858
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88729
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877501
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096046
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
NCI-H1650	GDSC Cell Line Gene Expression Profiles	-1.0	-1.99847
A498	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97917
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
Porphyrin metabolism	KEGG Pathways 2026	1.0	null
Dehydroisoandrosterone 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.249506
Estrone	MW Enzyme Metabolite Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-510	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30559
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09733
MED29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14503
mood disorder	GWASdb SNP-Disease Associations	1.0	0.35537
G361	CCLE Cell Line Gene CNV Profiles	1.0	1.33316
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36643
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF2_S_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93699
18537972-TableS4	GeneSigDB Published Gene Signatures	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825982
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3457
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide	HMDB Metabolites of Enzymes	1.0	null
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94004
Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
trans-3-Hydroxycotinine glucuronide	HMDB Metabolites of Enzymes	1.0	null
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
PMC3278830__F3	PFOCR Pathway Figure Associations 2023	1.0	null
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68655
JEG-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54815
A4-Fuk	GDSC Cell Line Gene Expression Profiles	1.0	3.13268
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04941
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93588
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11684
exons	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54945
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69704
Biological oxidations	Reactome Pathways 2014	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78954
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)	Reactome Pathways 2014	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956547
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181894
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6373-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hearing Loss	HuGE Navigator Gene-Phenotype Associations	1.0	null
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83335
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04105
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932324
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910751
SNU840	Achilles Cell Line Gene Essentiality Profiles	1.0	2.78866
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive organ benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
Valproic acid glucuronide	HMDB Metabolites of Enzymes	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42348
steroid metabolic process	GO Biological Process Annotations 2023	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1785
15-Hydroxynorandrostene-3,17-dione glucuronide	HMDB Metabolites of Enzymes	1.0	null
Cytosolic aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38304
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05967
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06722
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51917
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
benzo(a)pyrene 7,8-dihydrodiol	CTD Gene-Chemical Interactions	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0468
HCoV-EMC2012_0Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.33174
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052372
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10601
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3512
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824028
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52058
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6448
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42951
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.07
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49689
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
C2BBE1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12165
HCC364	Achilles Cell Line Gene Essentiality Profiles	1.0	1.08608
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1274
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933472
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01652
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26613
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8938
Bilirubin diglucuronide	HMDB Metabolites of Enzymes	1.0	null
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72314
Estrone glucuronide	HMDB Metabolites of Enzymes	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	5.82848
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
HIC1_01_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.90801
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.92203
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.68527
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27376
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46486
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05373
Kernicterus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66467
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10754
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)	Reactome Pathways 2014	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.5691
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1131
Medulla, motor related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59512
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3315
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05709
Neonatal jaundice	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77809
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04062
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44161
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140455
IMATINIB	DGIdb Drug Targets 2026	1.0	1.45019
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19832
small	GeneRIF Biological Term Annotations	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6628
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0222
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10484
GSE171826_1_v_3_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.3744
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.06664
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27355
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03111
Deoxycholic acid 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.4621
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2443
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.094022
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0222
3-alpha-Androstanediol glucuronide	HMDB Metabolites of Enzymes	1.0	null
glucuronate metabolic process	GO Biological Process Annotations 2023	1.0	null
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62969
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07402
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.228193
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Epinephrine glucuronide	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-298	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65385
KALS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinoic acid	MW Enzyme Metabolite Associations	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3274
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.176289
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923147
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.74672
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47308
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02948
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.44653
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89965
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04218
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08625
Aldosterone 18-glucuronide	HMDB Metabolites of Enzymes	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17668
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6241
within	GeneRIF Biological Term Annotations	1.0	null
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88849
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24786
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65879
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927631
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9944
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42367
Chemical carcinogenesis - receptor activation	KEGG Pathways 2026	1.0	null
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839056
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63886
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.688511
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48536
HCC-827	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052382
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4552
5-Hydroxy-6-methoxyindole glucuronide	HMDB Metabolites of Enzymes	1.0	null
Testosterone	MW Enzyme Metabolite Associations	1.0	null
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7444
tissues	GeneRIF Biological Term Annotations	1.0	null
steroid metabolic process	GO Biological Process Annotations 2025	1.0	null
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36282
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932017
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16065
nose	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE240109_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10678
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79512
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0225
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051257
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49528
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.321181
exhibited	GeneRIF Biological Term Annotations	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.39013
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883916
Morphine-6-glucuronide	MW Enzyme Metabolite Associations	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Estriol	MW Enzyme Metabolite Associations	1.0	null
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
microm	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99928
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06259
major depressive disorder	GWASdb SNP-Disease Associations	1.0	0.926808
17-beta-Estradiol glucuronide	HMDB Metabolites of Enzymes	1.0	null
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42744
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.832614
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7798
VMRC-MELG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862439
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055043
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20929
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29187
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
nasal mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25065
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47129
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78005
endoplasmic reticulum part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048828
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04657
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07608
Estrone 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930827
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.21951
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0989
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06336
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22895
KP-N-RT-BM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50429
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Morphine-3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.076
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.9572
ZNF700	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12127
endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182723
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052494
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14989
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
depression	GWASdb SNP-Phenotype Associations	1.0	0.81601
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.60005
(23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55329
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.814342
Hepatitis	CTD Gene-Disease Associations	1.0	1.12391
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04149
hsa-miR-4451	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Glucuronidation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8114
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.884
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14126
17-Hydroxyandrostane-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
EGFL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09144
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17387
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.035
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9051
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928533
CRCGN017_MCF10A.TP53.M_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18805
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16889
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3596
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)	Reactome Pathways 2014	1.0	null
RPMI-6666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16304
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
CAL-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76874
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25082
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30083
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4929
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-656	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Benzo(a)pyrene	CTD Gene-Chemical Interactions	1.0	null
Cortolone-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931562
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bilirubin glucuronide	HMDB Metabolites of Enzymes	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3731
SN-38	HMDB Metabolites of Enzymes	1.0	null
Clove	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832276
epithelium	GeneRIF Biological Term Annotations	1.0	null
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65112
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04533
ES6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.23201
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04318
Palmitoyl glucuronide	HMDB Metabolites of Enzymes	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15858
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
C8-MEF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48004
Female reproductive organ benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07123
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07398
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.81735
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.642
Phase II conjugation	Reactome Pathways 2014	1.0	null
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57104
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
Uridine 5'-diphosphate	HMDB Metabolites of Enzymes	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23718
peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.476027
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17211
C32	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.06025
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975429
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34052
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88819
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol	HMDB Metabolites of Enzymes	1.0	null
PMC6279925__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Cholic acid glucuronide	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.965115
Eosinophilia	CTD Gene-Disease Associations	1.0	1.06771
PMC3278830__F3	PFOCR Pathway Figure Associations 2024	1.0	null
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69273
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11768
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
Necrosis	CTD Gene-Disease Associations	1.0	1.69846
v-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416957
ITPRIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8571
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00106
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	2.02765
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143485
glucuronosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
COLO205	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00838
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11118
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38009
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.48069
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.6739
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25245
Long COVID	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.54111
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26718
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6731
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39666
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72253
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.268928
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04613
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62299
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6091
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824028
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2643
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02578
VSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25278
PMC6279925__F4	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7887
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92937
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6598
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2993
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72006
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0118
CRCGN014_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20895
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42729
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol	MW Enzyme Metabolite Associations	1.0	null
mainly	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52647
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974401
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26489
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
Dehydroepiandrosterone 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9465
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4997
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6118
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.64076
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14239
Metabolism	Reactome Pathways 2024	1.0	null
ps94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.804796
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9353
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86416
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.1593
HEP3B217	CCLE Cell Line Gene CNV Profiles	1.0	1.82241
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13651
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85903
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54271
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.377
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
Codeine	HMDB Metabolites of Enzymes	1.0	null
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79613
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60791
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38833
Polycyclic Hydrocarbons, Aromatic	CTD Gene-Chemical Interactions	1.0	null
gilbert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29003
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.042452
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07172
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67356
Morphine-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
ZYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5331
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63789
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60161
Testosterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79553
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844298
respiratory mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Androsterone	HMDB Metabolites of Enzymes	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48268
hsa-miR-3117-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.204
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00246
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13751
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15527
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60635
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824028
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52558
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40465
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.72968
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.5897
PMC7899452-media-4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70696
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
OSC20	DepMap CRISPR Gene Dependency	1.0	2.76744
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62299
respiratory epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825243
Liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19004
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16076
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93715
bronchoalveolar system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.32
Ketoprofen glucuronide	HMDB Metabolites of Enzymes	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78572
GRIK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49626
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07404
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38778
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
Disease	Reactome Pathways 2014	1.0	null
11-Hydroxyprogesterone 11-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Etiocholanolone glucuronide	HMDB Metabolites of Enzymes	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04234
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60671
rectum	HPA Tissue Protein Expression Profiles	1.0	0.814342
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.649344
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879069
occipito-temporal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941235
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.7574
A1207	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0224
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040439
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF15_02_140	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.0
25-Hydroxyvitamin D2-25-glucuronide	HMDB Metabolites of Enzymes	1.0	null
METRNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11368
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NCIH2171	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23664
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24891
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2786
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973617
CAOV3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.69518
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051387
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55435
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942178
MDA-MB-468	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55654
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70155
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.6051
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27756
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33115
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.33058
varied	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.36138
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930827
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081743
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16622
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4-Hydroxyandrostenedione glucuronide	HMDB Metabolites of Enzymes	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051644
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5094
Glucuronidation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0901
mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.658272
Estriol-16-Glucuronide	HMDB Metabolites of Enzymes	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8951
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3824
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7841
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08635
Fatty Liver	CTD Gene-Disease Associations	1.0	1.66102
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1552
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917395
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.7649
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
subfamily	GeneRIF Biological Term Annotations	1.0	null
SF126	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0745
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045732
Bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07316
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4815
SW1417	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37072
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0989
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23027
Defective UGT1A4 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
pentose and glucuronate interconversions	KEGG Pathways	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12926
glucuronosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25V-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395709
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11948
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1008
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CORO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32936
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41277
MAFK_02_183	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61667
medullary hindbrain (medulla)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27392
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4335
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.33701
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98302
GTF2F1_02_110	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.46508
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54322
Retinyl beta-glucuronide	HMDB Metabolites of Enzymes	1.0	null
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25223
COA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10489
Sleeping sickness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
monocarboxylic acid metabolic process	GO Biological Process Annotations 2025	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3081
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14335
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7567
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6104
Bile secretion	KEGG Pathways 2026	1.0	null
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
PFSK1	DepMap CRISPR Gene Dependency	1.0	3.02317
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03107
3-alpha-hydroxy-5-alpha-androstane-17-one 3-D-glucuronide	HMDB Metabolites of Enzymes	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2903
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26901
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3846
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185872_0_v_3_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09246
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29218
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88994
Olfactory ensheathing cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28387
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41233
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3578
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.269335
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60598
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.4639
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00241
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8039
Hymecromone	CTD Gene-Chemical Interactions	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31954
SCABER	DepMap CRISPR Gene Dependency	1.0	2.43321
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06789
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0577
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27238
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0536
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23046
DAOY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9086029__F6	PFOCR Pathway Figure Associations 2024	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041008
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824028
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.363
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3752
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1438
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60635
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28125
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09486
G-402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18617
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45363
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8269
rhombomere 8	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13192
Chemical carcinogenesis - DNA adducts	KEGG Pathways 2026	1.0	null
V-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30051
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60234
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79279
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.80265
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9094
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
KNS81	Achilles Cell Line Gene Essentiality Profiles	1.0	1.40756
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22112
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9926
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74597
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960583
EOL1	CCLE Cell Line Gene CNV Profiles	1.0	1.40298
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8299217-mmc3.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7517
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4012
endogenous depression	GWASdb SNP-Disease Associations	1.0	0.926808
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65918
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863916
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23586
2-Methoxyestradiol	HMDB Metabolites of Enzymes	1.0	null
COX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33278
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3204
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04214
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17-alpha-Estradiol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
kidney disease	GWASdb SNP-Disease Associations	1.0	0.835629
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32415
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064415
D-Glucuronic acid	HMDB Metabolites of Enzymes	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52165
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249664
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.73215
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039531
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.502353
PK45H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56212
DCXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48923
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906038
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4594
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24946
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11186
g.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94731
Estradiol	HMDB Metabolites of Enzymes	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.56501
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21392
LN-405	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42465
Inodxyl glucuronide	HMDB Metabolites of Enzymes	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	4.5258
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H510A	GDSC Cell Line Gene Expression Profiles	1.0	1.41882
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28609
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54127
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31731
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
detoxification	GeneRIF Biological Term Annotations	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Reactome Pathways 2014	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20179
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5581
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23596
SNU-423	GDSC Cell Line Gene Expression Profiles	-1.0	-2.61958
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061503
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.180634
11-beta-Hydroxyandrosterone-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11487
Prostate adenocarcinoma_PRAD_TCGA-G9-6329-01A-13R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27942
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2450	DepMap CRISPR Gene Dependency	1.0	5.31165
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20539
hearing loss	GAD Gene-Disease Associations	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.52591
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060609
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045655
QGP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.38811
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P2URK562	DepMap CRISPR Gene Dependency	1.0	3.27364
RAB40C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93859
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48246
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
Testosterone glucuronide	MW Enzyme Metabolite Associations	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07316
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057386
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42176
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.985858
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79321
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1472
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57156
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.57939
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.1823
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91277
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04913
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4811
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2769
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5185
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	90.15
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.7627
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14786
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.45659
Uterine benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
TCCSUP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.40821
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97628
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88593
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7491
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11093
Tyramine glucuronide	HMDB Metabolites of Enzymes	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3633
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78158
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.793543
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835277
Glucuronidation	Reactome Pathways 2024	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.730213
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798541
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	3.21582
OVCA420	DepMap CRISPR Gene Dependency	1.0	10.06
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
Gilbert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69775
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.228193
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14168
Medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2097
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70265
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60615
1-Salicylate glucuronide	HMDB Metabolites of Enzymes	1.0	null
Cecum mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1633
DK-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01381
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05416
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	6.91236
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
U251MG	CCLE Cell Line Gene CNV Profiles	1.0	2.40896
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25065
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.929084
Fever	CTD Gene-Disease Associations	1.0	1.10872
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7546
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96605
only	GeneRIF Biological Term Annotations	1.0	null
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.881204
GSE179868,GSE180330_1_v_0_ddx21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17321
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.66065
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.58584
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824028
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.27575
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)	Reactome Pathways 2014	1.0	null
Glucuronidation	WikiPathways Pathways 2024	1.0	null
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7717
periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.56284
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00722
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26314
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02644
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891103
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29389
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2641
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98631
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61459
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44238
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1275
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1087
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931562
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2945
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7192
Weight Loss	CTD Gene-Disease Associations	1.0	1.2137
Benzoyl glucuronide (Benzoic acid)	HMDB Metabolites of Enzymes	1.0	null
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.502
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30855
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8576
Trichloroethanol glucuronide	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.00635
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12712
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239307
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03111
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8305
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
starch and sucrose metabolism	KEGG Pathways	1.0	null
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21802
AR	ChEA Transcription Factor Targets	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31325
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0506
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45089
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52058
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8576
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.984493
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	1.33457
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53356
U-87-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883826
PLK1_knockdown_98_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70076
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8809
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-582-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.03083
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0222
ESO26	DepMap CRISPR Gene Dependency	1.0	2.11416
SUM149PT	DepMap CRISPR Gene Dependency	1.0	3.49834
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71747
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20058
BBX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43136
porphyrin and chlorophyll metabolism	KEGG Pathways	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
beta-D-Glucuronoside	MW Enzyme Metabolite Associations	1.0	null
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02541
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02732
microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.473617
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78071
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34857
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7913
Fibrosis	CTD Gene-Disease Associations	1.0	1.52388
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.40371
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37154
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2-Methoxyestrone 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02304
nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171937
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09518
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20337
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2588
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35832
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81344
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.394
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
Dextrorphan O-glucuronide	HMDB Metabolites of Enzymes	1.0	null
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83334
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29252
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOM1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27209
variant	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
AGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.64375
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38211
drug-related genes	GAD Gene-Disease Associations	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.41942
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97883
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07952
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95311
hsa-miR-4799-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49528
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57596
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.075229
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.933195
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9912
SCC-15	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65096
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22158
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.037
Infertility, Male	CTD Gene-Disease Associations	1.0	1.10246
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061687
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3066
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33985
WM88	DepMap CRISPR Gene Dependency	1.0	3.2016
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28267
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91041
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78994
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
ugt2a1	GeneRIF Biological Term Annotations	1.0	null
19074828-TableS4	GeneSigDB Published Gene Signatures	1.0	null
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47862
CDC14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63896
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8681
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51446
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
Pulse pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.55229
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040393
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9453
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966573
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53343
Metabolism of xenobiotics by cytochrome P450	KEGG Pathways 2026	1.0	null
PMC5902498-41598_2018_24445_MOESM3_ESM.xlsx-GATA1_ChIP-Seq_peaks-Unnamed_5_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01087
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54065
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.84481
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
different	GeneRIF Biological Term Annotations	1.0	null
ZBTB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88073
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2-Phenylethanol glucuronide	HMDB Metabolites of Enzymes	1.0	null
DAOY	DepMap CRISPR Gene Dependency	1.0	2.14659
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7581
3-alpha,20-alpha-Dihydroxy-5-beta-pregnane 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
MEG-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.869
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06774
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75912
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0989
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931562
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.7247
NCIH1915	DepMap CRISPR Gene Dependency	1.0	3.03614
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.45348
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
Aspirin ADME	Reactome Pathways 2024	1.0	null
GaMG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.5077
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.3483
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.962739
Edema	CTD Gene-Disease Associations	1.0	1.5745
6-Hydroxy-5-methoxyindole glucuronide	HMDB Metabolites of Enzymes	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47456
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YH-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.09454
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05625
other	GAD High Level Gene-Disease Associations	1.0	0.293278
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10386
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35966
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22568
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.82874
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.1848
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52152
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.795311
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
PMC11694450-Table_1.xlsx-MR_to_MM_at_2_DPI-Unnamed_10_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-380	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
rhombomere 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10393
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.902254
cellular glucuronidation	GO Biological Process Annotations 2023	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9516
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07734
Estriol	HMDB Metabolites of Enzymes	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3951
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40278
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subcuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836634
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4108
SARS-BatSRBD_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.26156
Hepa-RG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37858
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2143
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02788
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71068
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14132
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30941
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80032
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
1-hydroxybenzo(a)pyrene	CTD Gene-Chemical Interactions	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
increased vertical activity	IMPC Knockout Mouse Phenotypes	1.0	null
fascioliasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.07026
kernicterus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0071
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047127
nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.43227
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6558
glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.648138
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.263
Mental Disorders	CTD Gene-Disease Associations	1.0	1.4591
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.76725
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6544
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
Bilirubin	HMDB Metabolites of Enzymes	1.0	null
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
RANBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70862
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
ADH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20343
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
KM12	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11628
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17302
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824563
Thyroxine glucuronide	HMDB Metabolites of Enzymes	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8803
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63675
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.663916
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.640327
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47501
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28307
juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174278
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54788
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31393
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38462
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12837
Entorhinal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
aromatic	GeneRIF Biological Term Annotations	1.0	null
Estrone	HMDB Metabolites of Enzymes	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052562
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830574
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88783
PMC11237666-spectrum.03516-23-s0004.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Androsterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8175
pontomedullary hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08536
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12818
Phenethylamine glucuronide	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65178
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0961
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983435
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71341
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932324
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
hsa-miR-513b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.382
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16858
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50547
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47014
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4141
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1517
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26245
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08754
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.347
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3,17-Androstanediol glucuronide	HMDB Metabolites of Enzymes	1.0	null
HMV-II	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66958
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.05
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7653
5-alpha-Dihydrotestosterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	2.50399
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid	HMDB Metabolites of Enzymes	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2045
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07481
Drug metabolism - other enzymes	KEGG Pathways 2026	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11149
olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27023
Phase II - Conjugation of compounds	Reactome Pathways 2024	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409351
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48746
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2
PA-TU-8902	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)	Reactome Pathways 2014	1.0	null
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94744
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53095
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.45521
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-196a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
values	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16212
Cotinine glucuronide	HMDB Metabolites of Enzymes	1.0	null
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43929
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59941
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05584
Pregnanediol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
olfactory lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27947
Retinoyl b-glucuronide	HMDB Metabolites of Enzymes	1.0	null
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280717
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23824
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0348
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.082
Brain Diseases	CTD Gene-Disease Associations	1.0	1.23899
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3636
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39934
MKN7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04392
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87308
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347038
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841491
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075502
frontal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
bile acid metabolic process	GO Biological Process Annotations 2025	1.0	null
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
doxorubicin_homo sapiens_gpl550_gds846	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	2.29093
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111613
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
NANOG	ChEA Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.94519
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10634
Osseous plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.8176
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	1.0	1.45313
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14104
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	3.21977
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17871
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11223
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19986
LRP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44991
hsa-miR-196b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Estriol-17-glucuronide	HMDB Metabolites of Enzymes	1.0	null
PMC9204905__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.09786
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16531
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7909
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75597
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.215
SKOV3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01656
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38009
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.04239
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5207
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29417
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38275
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.04314
all-trans-Retinoyl-beta-glucuronide	MW Enzyme Metabolite Associations	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06704
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16413
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.428881
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3646
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13519
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.875
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4433
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8759
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35012
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8576
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04871
hsa-miR-2392	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
CORL23	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.37807
hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11118
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	118.735
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03855
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88749
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20038
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0794
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37156
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43229
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4876
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867514
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06004
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34589
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7323
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2097
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33822
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9887
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185249
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.904032
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19527
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03111
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.03641
Organ system benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
LN-405	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38461
POU3F2	ChEA Transcription Factor Targets	1.0	null
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPMI8402	CCLE Cell Line Gene CNV Profiles	1.0	1.91484
olfactory bulb	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9829
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88729
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
MAPK1_knockdown_112_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.06785
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34906
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27072
Geniculate group, dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01948
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00332
lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098281
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22338
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02198
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3285
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
monocarboxylic acid metabolic process	GO Biological Process Annotations 2023	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0311
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82196
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0566
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078272
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923834
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060658
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53855
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04168
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3464
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82195
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29613
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39253
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027764
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05288
olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
sensory perception	GO Biological Process Annotations 2023	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.82542
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.4639
Codeine-6-glucuronide	HMDB Metabolites of Enzymes	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03431
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01521
LMSU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92827
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54607
496100306_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27928
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tetrahydroaldosterone-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24637
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31705
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4362
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53631
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8576
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5434
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.04
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62299
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.95988
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1-naphthol	CTD Gene-Chemical Interactions	1.0	null
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93124
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2313
Estriol 3-sulfate 16-glucuronide	HMDB Metabolites of Enzymes	1.0	null
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295297
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6368
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21187
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36113
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63332
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04633
ventral tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10117
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5102
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
intestine	GeneRIF Biological Term Annotations	1.0	null
r7 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40314
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01491
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05453
CRCGN011_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21005
Indomethacin	CTD Gene-Chemical Interactions	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7081
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045148
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.18901
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03738
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55735
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53148
UDP-glycosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36282
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
2-Methoxyestrone	HMDB Metabolites of Enzymes	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5469
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09811
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48282
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240497
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04615
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4405
similar	GeneRIF Biological Term Annotations	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.772759
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90682
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933472
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58624
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68047
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03018
Glucuronic acid	MW Enzyme Metabolite Associations	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49002
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
TPST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56041
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.9456
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8595
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36882
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12119
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.954237
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918326
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
Morphine-6-glucuronide	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-362-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.02725
SGTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36451
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42951
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
hydrocarbons	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.248
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51314
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08635
tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.720345
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08711
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.66511
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3718
hsa-miR-500b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.781
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65198
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69412
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041794
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79213
crigler-najjar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0071
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB7_01_169	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.15946
ugt2a3	GeneRIF Biological Term Annotations	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.2602
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
KLF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Type 2 diabetes mellitus_Hepatic Tissue_GSE2899	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.79825
hsa-miR-1231	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87832
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25324
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87077
Drug metabolism - cytochrome P450	KEGG Pathways 2026	1.0	null
VCAP	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05359
PMC3470785-NIHMS377161-supplement-3.pdf-472-EMX2_EMX2	Rummagene Transcription Factor Associations 2026	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1229
AKR1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28876
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938365
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9361
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21924
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47631
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81502
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54286
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.4761
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06637
singlenucleotide	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.98285
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.122873
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.504
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973612
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.43451
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.160247
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07309
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326432
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064051
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.1008
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189034
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835277
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5128
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970998
FTC238	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74885
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2497
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49539
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6398
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.431894
hsa-miR-3674	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58958
PANC-08-13	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54256
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13658
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.79926
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954604
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65103
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14845
PHH	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49126
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983859
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845321
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909767
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
Acute Myeloid Leukemia_LAML_TCGA-AB-2950-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XRCC5_02_114	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
dibenzo(a,l)pyrene 11,12-dihydrodiol	CTD Gene-Chemical Interactions	1.0	null
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61827
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.6733
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.46517
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.198769
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345188
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31669
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83176
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13499
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981146
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3828
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29252
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8576
ERV3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43924
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02328
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.063888
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
choline deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.22995
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39666
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25169
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.251
hexosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
6-Dehydrotestosterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92216
Adrenocortical carcinoma_ACC_TCGA-PK-A5HA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24202
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.5576
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30051
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.0496
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26613
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11226
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
1,2-dihydro-1,2-dihydroxy-5-methylchrysene	CTD Gene-Chemical Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMO1	DepMap CRISPR Gene Dependency	1.0	4.53871
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.52919
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87311
Biological oxidations	Reactome Pathways 2024	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.50979
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.94399
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056913
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52988
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16208
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982957
liver	GeneRIF Biological Term Annotations	1.0	null
UDP-glucuronosyl/UDP-glucosyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P4HA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73074
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35611
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8214
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01652
Pentose and glucuronate interconversions	KEGG Pathways 2026	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931278
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60988
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.25134
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96822
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07481
PMC12784616-12711_2025_1028_MOESM2_ESM.xlsx-TableS8-Table_S8_Summary_of_significant_MR_associations_in_liver_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30207
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.814342
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91762
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983576
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
Prostate adenocarcinoma_PRAD_TCGA-VP-A878-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874482
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2595
udpglucuronosyltransferase	GeneRIF Biological Term Annotations	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3455
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90672
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883826
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62852
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2058
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12209
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6415
PMC8482137__F4	PFOCR Pathway Figure Associations 2024	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20801
LARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28371
Etiocholanolone	MW Enzyme Metabolite Associations	1.0	null
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21832
Rectum adenocarcinoma_READ_TCGA-CI-6624-01C-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UDP	MW Enzyme Metabolite Associations	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33318
hsa-miR-4517	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06983
MMAC	DepMap CRISPR Gene Dependency	1.0	5.1237
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6972
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3211
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1083
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2013
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974401
MERO14	DepMap CRISPR Gene Dependency	1.0	2.01242
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38344
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2884
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6665
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13192
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.936
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59219
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0763
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12441
POU2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88771
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67733
NNAL-N-glucuronide	HMDB Metabolites of Enzymes	1.0	null
All-trans-retinoic acid	HMDB Metabolites of Enzymes	1.0	null
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
Hyperplasia	CTD Gene-Disease Associations	1.0	1.36047
hsa-miR-4261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hexosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.125961
C9-MEF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56252
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29433
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16859
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7417
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893828
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37874
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49428
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16817
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23435
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UDP-glucuronic acid	MW Enzyme Metabolite Associations	1.0	null
Cholesterol glucuronide	HMDB Metabolites of Enzymes	1.0	null
Defective GGT1 causes Glutathionuria (GLUTH)	Reactome Pathways 2014	1.0	null
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86354
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5672
glucosephosphate dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.31464
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057015
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Metabolism	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6095
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.077
Cholestane-3,7,12,25-tetrol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Ascorbate and aldarate metabolism	KEGG Pathways 2026	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73739
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22658
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3-hydroxybenzo(a)pyrene	CTD Gene-Chemical Interactions	1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992421
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.8088
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925164
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10695
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
VEZF1_02_179	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56765
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
Uterine fibroid	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
CRCGN014_HEPG2_3H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5961
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.0685
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36178
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824028
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69043
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9469
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
K562	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05185
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945314
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03735
hsa-miR-1245	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1028
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
androgen and estrogen metabolism	KEGG Pathways	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Testosterone	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1327
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.556467
2-Methoxy-17beta-estradiol	MW Enzyme Metabolite Associations	1.0	null
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.644074
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47544
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0093
Retinol metabolism	KEGG Pathways 2026	1.0	null
Nicotine glucuronide	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	13.1027
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882632
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36882
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2756
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.84852
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68818
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5965
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2577
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09438
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.707
U-2-OS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT116	DepMap CRISPR Gene Dependency	1.0	2.41239
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9758
2-Methoxyestrone 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45028
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
PMC7887593-ADVS-8-2003526-s002.xlsx-TT_AR_vs_BR-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20249
3-Methoxy-4-hydroxyphenylglycol glucuronide	HMDB Metabolites of Enzymes	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05175
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3723
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44626
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
SN38 glucuronide	HMDB Metabolites of Enzymes	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45925
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064509
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.87152
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371245
Androsterone 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Bilirubin	MW Enzyme Metabolite Associations	1.0	null
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91596
LIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97447
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
HDLM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tobacco	GeneRIF Biological Term Annotations	1.0	null
snps	GeneRIF Biological Term Annotations	1.0	null
11-Oxo-androsterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.61179
hsa-miR-592	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15845
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10261
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3232
HMCES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89816
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinogens	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Acute Coronary Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8545
metabolism of xenobiotics by cytochrome p450	KEGG Pathways	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	2.09942
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1873
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07997
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59514
Poisoning	CTD Gene-Disease Associations	1.0	1.11809
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871314
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59319
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8179
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27576
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.1835
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38673
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39231
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867514
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33124
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.530768
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9482
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931562
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61459
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867514
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.337608
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883826
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08715
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095915
IM95	DepMap CRISPR Gene Dependency	1.0	4.01581
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7105
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
25-Hydroxyvitamin D2 25-(beta-glucuronide)	HMDB Metabolites of Enzymes	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.36032
MMP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43359
splice	GeneRIF Biological Term Annotations	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.052396
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16099
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60569
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835277
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51777
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961639
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03945
Glycochenodeoxycholic acid 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
PMC7188667__F1	PFOCR Pathway Figure Associations 2023	1.0	null
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341495
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
Lung squamous cell carcinoma_LUSC_TCGA-68-8250-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01618
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36415
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO-668	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77563
disease	GWASdb SNP-Disease Associations	1.0	0.031563
bile acid metabolic process	GO Biological Process Annotations 2023	1.0	null
Benign neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
CCDC71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76428
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40401
BE-13	GDSC Cell Line Gene Expression Profiles	1.0	2.07691
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22981
17-beta-Estradiol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13735
sensory perception	GO Biological Process Annotations 2025	1.0	null
ugt2a	GeneRIF Biological Term Annotations	1.0	null
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84645
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57063
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15185
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9606
Lung-respiratory goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	3.49358
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29822
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25546
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6693
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3374
WM1799	CCLE Cell Line Gene CNV Profiles	-1.0	-2.52374
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55283
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16611858-FLUSetTable	GeneSigDB Published Gene Signatures	1.0	null
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050842
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53081
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3633
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2012
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35897
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33373
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27215
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40716
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21193
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.21678
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74292
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.794375
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35691
ADSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29625
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8815
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314772
Isovalerylglucuronide	HMDB Metabolites of Enzymes	1.0	null
Water	HMDB Metabolites of Enzymes	1.0	null
RALGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29013
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28298
Basal labyrinth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12316
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902113
hsa-miR-4503	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6428
Testosterone sulfate	HMDB Metabolites of Enzymes	1.0	null
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60905
carcinogenesis	GeneRIF Biological Term Annotations	1.0	null
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7706
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29296
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8188
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02318
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.43103
NCI-H2030	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59413
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.681292
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1315
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.564112
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9595
CDR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43382
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21853
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911248
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31714
Etiocholanolone	HMDB Metabolites of Enzymes	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042614
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.1155
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422673
HCC1599	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04627
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1777
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23649
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1517
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.06808
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55086
Triiodothyronine glucuronide	HMDB Metabolites of Enzymes	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046481
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6679
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063755
Metapathway biotransformation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31133
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26563
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Drug ADME	Reactome Pathways 2024	1.0	null
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Epithelial Ovarian Cancer	DisGeNET Gene-Disease Associations	1.0	null
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50295
Metapathway biotransformation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15599
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64262
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
enzyme	GeneRIF Biological Term Annotations	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.641267
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2022
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.047465
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Androsterone	MW Enzyme Metabolite Associations	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.027
hsa-miR-645	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3779
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30754
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61181
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.27217
Ruminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840547
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853339
NB7	DepMap CRISPR Gene Dependency	1.0	4.9354
beta-Estradiol	MW Enzyme Metabolite Associations	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09866
ugts	GeneRIF Biological Term Annotations	1.0	null
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.3201
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44715
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_4_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66772
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)	Reactome Pathways 2014	1.0	null
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58641
HCC202	DepMap CRISPR Gene Dependency	1.0	5.22006
Oviductal ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
2,2,2-Trichloroethanol	HMDB Metabolites of Enzymes	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11949
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6783
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368998
Oligospermia	CTD Gene-Disease Associations	1.0	1.05828
tissue	GeneRIF Biological Term Annotations	1.0	null
Inappropriate ADH Syndrome	CTD Gene-Disease Associations	1.0	1.06808
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86163
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08021
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00945
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35032
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15119
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.977182
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.814342
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7394
1-hydroxypyrene	CTD Gene-Chemical Interactions	1.0	null
polycyclic	GeneRIF Biological Term Annotations	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39469
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10535
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911992
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76293
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08839
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2238
HS-578-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05834
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20447
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84243
member	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.837049
ZNF48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73525
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61798
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03091
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3152
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74351
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47829
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2601
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39408
Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.13862
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987247
all	GWASdb SNP-Phenotype Associations	1.0	0.034853
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03542
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.776079
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94286
rhombomere 7	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12737
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H460	GDSC Cell Line Gene Expression Profiles	-1.0	-2.22469
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0186
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.24687
shares	GeneRIF Biological Term Annotations	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8658
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
primarily	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6666-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Estriol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
mental depression	GWASdb SNP-Disease Associations	1.0	0.467134
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835277
RAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50784
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.494
Morphine	HMDB Metabolites of Enzymes	1.0	null
PMC7899452-media-5.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253908
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45011
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17564
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87267
Metapathway biotransformation Phase I and II	WikiPathways Pathways 2024	1.0	null
Dopamine glucuronide	HMDB Metabolites of Enzymes	1.0	null
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33131
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.41805
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.41781
p2 part of the zona limitans core population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07817
ugt2a2	GeneRIF Biological Term Annotations	1.0	null
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.96589
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1797
glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.647743
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50953
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5786
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.24984
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7592
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6513
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74397
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45363
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.19263
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1835
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1417	Achilles Cell Line Gene Essentiality Profiles	1.0	1.04927
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972426
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93715
Thalamus, sensory-motor cortex related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05039
AM38	DepMap CRISPR Gene Dependency	1.0	8.57753
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06562
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1616
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.645
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.33769
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047243
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-940	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GMEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49397
r8 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05073
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947484
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71747