association	dataset	threshold value	standardized value
CARD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761051
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4063
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
ion binding	GO Molecular Function Annotations 2015	1.0	null
MFE-296	GDSC Cell Line Gene Expression Profiles	-1.0	-1.68866
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
TMEM63B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6275
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.585
Glucuronidation	WikiPathways Pathways 2024	1.0	null
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9768
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
BRD-K22725588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23304
BRD-K87670244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44046
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
BRD-K03606830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43161
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79592
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
BRD-K14181473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22627
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24274
Sandosaponin B	HMDB Metabolites of Enzymes	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.153
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K47441131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92011
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499223
BRD-K66463856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98129
Hepatic artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
Hydathode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
BRD-K62624148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31437
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
5-alpha-Dihydrotestosterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
Cystitis	CTD Gene-Disease Associations	1.0	1.04051
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9382
2,2,2-Trichloroethanol	HMDB Metabolites of Enzymes	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466885
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
all	GWASdb SNP-Phenotype Associations	1.0	0.030885
RBMS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681193
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9627
POLR2A	ENCODE Transcription Factor Targets	1.0	null
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PAX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642905
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10624
BRD-K80009401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32842
ZNF563	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82976
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29694
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
BRD-K86448296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67154
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2716
BRD-K25075258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00641
Phase II conjugation	Reactome Pathways 2014	1.0	null
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11485
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Reticuloendothelial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.842982
Ammonium transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.903
xenobiotic glucuronidation	GO Biological Process Annotations 2023	1.0	null
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65379
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51453
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53069
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835688
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9928
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34583
indicated	GeneRIF Biological Term Annotations	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.546
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Progressive familial intrahepatic cholestasis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29833
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06743
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21779
(3a,5b)-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl-b-D-Glucopyranosiduronic acid	HMDB Metabolites of Enzymes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37564
Prepupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25107
UDP-D-galacturonate	HMDB Metabolites of Enzymes	1.0	null
BRD-K72073851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25544
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
LRRC15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658005
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9326
choline deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.729357
H4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80081
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K63171151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16416
depression	GWASdb SNP-Phenotype Associations	1.0	0.778318
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
NDUFV1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639892
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45516
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9135
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05702
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Steroid hormone biosynthesis	KEGG Pathways 2026	1.0	null
hsa-miR-624	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K58708811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14608
L33	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.29007
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67039
cellular response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K66311249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24297
BRD-K41287744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87961
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inodxyl glucuronide	HMDB Metabolites of Enzymes	1.0	null
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.40237
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09782
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354455
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11963
NDUFS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662013
KIF5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561749
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3W-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31618
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.067
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
5-Hydroxy-6-methoxyindole glucuronide	HMDB Metabolites of Enzymes	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.96
pattern	GeneRIF Biological Term Annotations	1.0	null
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88841
H4C9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00738933
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043358
L-5178-Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40349
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
D-Glucuronic acid 1-phosphate	HMDB Metabolites of Enzymes	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35775
result	GeneRIF Biological Term Annotations	1.0	null
lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.647316
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01399
BRD-K79619334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08026
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338177
BRD-K43992442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25311
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142417
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
uronic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499223
BRD-K50140257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79553
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073822
BRD-K40476324_Digoxin_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
membrane part	GO Cellular Component Annotations 2015	1.0	null
Intestinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
chr4_69545677_A_T_b38	GTEx eQTL 2025	1.0	10.0467
breast cancer; testosterone; estradiol	GAD Gene-Disease Associations	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.896
major depressive disorder	GWASdb SNP-Disease Associations	1.0	0.886521
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963488
BRD-K36197756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37346
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Quercetin 3-O-glucuronide	HMDB Metabolites of Enzymes	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glucuronidation	Reactome Pathways 2014	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6522
cyp2d6	GeneRIF Biological Term Annotations	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075777
Retinoyl b-glucuronide	HMDB Metabolites of Enzymes	1.0	null
triglyceride-rich lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.293637
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92793
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04058
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1092
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262645
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376494
retinoic acid binding	GO Molecular Function Annotations 2023	1.0	null
ZZZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78927
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.50433
Biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
cellular process	GO Biological Process Annotations 2015	1.0	null
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08366
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395709
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82723
CHIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614697
BRD-K60053695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1725
deoxynivalenol-15-glucuronide	CTD Gene-Chemical Interactions	1.0	null
estrogen metabolic process	GO Biological Process Annotations 2015	1.0	null
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19267
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
Fatty Liver	CTD Gene-Disease Associations	1.0	1.27813
Ovarian theca-interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15907
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01095
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Perturb_12538_KO_FBXO11_SRP278534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K98465548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29707
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6576
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A24396574_celastrol_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ABCC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0045579
regulation of hormone levels	GO Biological Process Annotations 2015	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9252
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8233_KD_RBM15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.43037
3,17-Androstanediol glucuronide	HMDB Metabolites of Enzymes	1.0	null
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9627
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056973
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12392
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.17497
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58796
Estrone	HMDB Metabolites of Enzymes	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7578
Acaciabiuronic acid	HMDB Metabolites of Enzymes	1.0	null
ART3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709432
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
BRD-K57026098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05273
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08678
BRD-K66425065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52884
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3994
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26347
BRD-K18070214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58318
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.00631
PHH	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
BRD-K15508005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79598
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.82638
CACO-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5109
pericardium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31258
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
pentose and glucuronate interconversions	KEGG Pathways	1.0	null
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22684
Tetrahydroaldosterone-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3279
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
mepyramine-3184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21098
flavonoid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HUWE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486318
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36365
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851367
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
CD300LB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060134
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.50045
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
VCAP	Achilles Cell Line Gene Essentiality Profiles	1.0	2.82212
BRD-K82105033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36224
hyodeoxycholic acid	CTD Gene-Chemical Interactions	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KP4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.88408
intracellular part	GO Cellular Component Annotations 2015	1.0	null
proton-transporting two-sector ATPase complex, catalytic domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.463
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40678
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70632
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary Biliary Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68371
2-O-(4-O-Methyl-a-D-glucopyranuronosyl)-D-xylose	HMDB Metabolites of Enzymes	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.438
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-369-TTF1_TTF1	Rummagene Transcription Factor Associations 2026	1.0	null
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17773
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046458
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.75452
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16829
Deoxycholic acid 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4901
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HAVCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595611
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115164
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
IDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88101
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39066
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863079
Tuberoside B (Ullucus tuberosus)	HMDB Metabolites of Enzymes	1.0	null
BRD-K90756713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22366
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
retinoid binding	GO Molecular Function Annotations 2025	1.0	null
Bipolar I disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
PITX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42503
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K75331656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6042
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
Retinoic acid	MW Enzyme Metabolite Associations	1.0	null
BRD-K54637865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00295
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182375
Triiodothyronine glucuronide	HMDB Metabolites of Enzymes	1.0	null
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69613
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36831
Aspirin ADME	Reactome Pathways 2024	1.0	null
Uridine 5'-diphosphate	HMDB Metabolites of Enzymes	1.0	null
glucuronosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
Vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.518
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.852608
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947817
sitosterol-4073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uridine diphosphate glucuronic acid	HMDB Metabolites of Enzymes	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GANC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523014
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17434
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05351
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39657
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20951
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00641
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
Dehydroepiandrosterone 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
CSF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526894
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18865
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.279748
BRD-K37634338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18043
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
BRD-K27121064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88016
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76829
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.297089
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)	Reactome Pathways 2014	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
SKCO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.68063
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.46515
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49494
ABCG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533314
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05573
Fruit juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
Codeine-6-glucuronide	HMDB Metabolites of Enzymes	1.0	null
CAL78	CCLE Cell Line Gene Expression Profiles	1.0	1.35452
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938571
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.45554
BRD-K10847374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2338
Drug metabolism - other enzymes	KEGG Pathways 2026	1.0	null
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
proton-transporting V-type ATPase, V1 domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
Ethyl glucuronide	HMDB Metabolites of Enzymes	1.0	null
NQO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578144
Biological oxidations	Reactome Pathways 2024	1.0	null
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	1.43984
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53325
Perturb_8068_KD_NONO_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31397
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
dyslexia	GWASdb SNP-Disease Associations	1.0	0.692261
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.06465
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32821
PMC7275405__F8	PFOCR Pathway Figure Associations 2024	1.0	null
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53428
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.863805
Amniotic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
PDK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00626048
CBX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460973
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73995655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51299
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98925
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.069045
GATA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00313166
LEDGF_KD_GDS1580_249_human_293T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Synergid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
Palmitoyl glucuronide	HMDB Metabolites of Enzymes	1.0	null
DAGLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00821344
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8138
BRD-K44950949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30911
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
Ovarian Failure, Premature	HuGE Navigator Gene-Phenotype Associations	1.0	null
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84328
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20061970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37473
BRD-K11487484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.079
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
Gastric juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50295
Kaempferol 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	2.24546
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4113
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03878
BRD-K40776502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96756
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08542
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.963488
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
CHIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052618
SAFB2_02_102	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.66816
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.81939
Extraorganismal space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.147
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8175_KD_PNPT1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.45504
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12535
BRD-K71274071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08604
KDM5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29246
Congenital dyserythropoietic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
CRCGN014_HEPG2_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0285
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
KU-19-19	GDSC Cell Line Gene Expression Profiles	-1.0	-2.16612
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.2636
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X2-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL5	DepMap CRISPR Gene Dependency	1.0	3.12925
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16392
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Metabolism	Reactome Pathways 2024	1.0	null
DGAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550558
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09204
BRD-K57937572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02743
AGS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48959
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326432
CORL23	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.90055
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
2-Methoxyestradiol	HMDB Metabolites of Enzymes	1.0	null
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.26399
ID1_01_117	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.96829
BRD-K43680691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42411
UTS2R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0077007
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46377
REV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68429
STING1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607778
BRD-A55722685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11896
BRD-K56836463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68692
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37752
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.772338
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04886
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAP3K14	MSigDB Cancer Gene Co-expression Modules	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05648
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
BRD-K84203638_4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-(4-methylpyridin-2-yl)butanamide_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_14115_KD_HTT_SRP156289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.37422
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78769
LS411N	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.3222
MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
patu8988t	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K23556321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12334
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal Diseases	CTD Gene-Disease Associations	1.0	1.18751
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
CRCGN017_MCF10A.TP53.M_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20103
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85873
Obstructive jaundice	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amobarbital	CTD Gene-Chemical Interactions	1.0	null
ZNF326	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33991
PMC11285334-40001_2024_1982_MOESM6_ESM.pdf-44-CREB1_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
neurodevelopmental abnormality	GWASdb SNP-Phenotype Associations	1.0	0.593884
NSF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475292
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40993
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.98445
BRD-K19527338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27933
NR2F2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2301
XCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467255
CALU1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.20495
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8165
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38255
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1445
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59131
TM9SF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8779
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93198
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48555
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28155
BRD-K75814223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46439
catabolic process	GO Biological Process Annotations 2015	1.0	null
DACH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00404989
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Non-Alcoholic Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
Hyaluronan	HMDB Metabolites of Enzymes	1.0	null
BRD-K85985071_E3380_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
MDA-MB-415	GDSC Cell Line Gene Expression Profiles	1.0	3.44353
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494136
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10177
strongly	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11924
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69737
BRD-K11004561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02555
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25262
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86718
PMC7275405__F8	PFOCR Pathway Figure Associations 2023	1.0	null
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NEK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684935
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
PARP2_KD_GSE43981_676_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
ACLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504545
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Reactome Pathways 2014	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042491
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89101
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
BRD-K40255344_EI-215_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.53566
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.165
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPRT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00480346
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089942
BRD-K45185240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3309
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
KCNK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608439
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65245
BRD-K12836153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70587
BRD-K14211116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24495
2-Phenylethanol glucuronide	HMDB Metabolites of Enzymes	1.0	null
AICD_Induced  expression / Over-expression_GDS1979_288_human_SHEP-SF neuroblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GP2D	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15381
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979611
MELJUSO	CCLE Cell Line Gene Expression Profiles	-1.0	-2.67958
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20552
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8224
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9043
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08446
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16644
methadone	GeneRIF Biological Term Annotations	1.0	null
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
DK-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288514
HAVCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571351
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703945
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
Intrahepatic cholestasis of pregnancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Progressive familial intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
SLC36A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00921309
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.779
Nuclear receptors meta pathway	WikiPathways Pathways 2024	1.0	null
CTH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519883
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
Dubin-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.928
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89689
BRD-K34701680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18764
BRD-K26314798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18245
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
TNFSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561747
RAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50784
Lablaboside E	HMDB Metabolites of Enzymes	1.0	null
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
BRD-K32476586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91654
Hereditary spherocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
ABCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627161
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66661
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32904
BRD-K26786741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03084
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81987
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12773
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0304
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ODF3L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00894595
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851367
HNF4A	ENCODE Transcription Factor Targets	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08752
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23421
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1152
BRD-K88080911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01951
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
NCIH1355	DepMap CRISPR Gene Dependency	1.0	3.94087
protein-lipid complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.128063
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.854209
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
N6-Galacturonyl-L-lysine	HMDB Metabolites of Enzymes	1.0	null
Ornithine carbamoyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087992
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
monocarboxylic acid binding	GO Molecular Function Annotations 2023	1.0	null
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
PMC9117466-NIHMS1784916-supplement-Supplementary_Tables_1_to_7.xlsx-Table_3-Supplementary_Table_3_HOXB13-repressed_genes_that_were_or_were_not_rescued_by_G84E_in_Fig_1a_HOXB13	Rummagene Transcription Factor Associations 2026	1.0	null
predicted	GeneRIF Biological Term Annotations	1.0	null
Colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.754
BRD-K56588599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65337
EKVX	GDSC Cell Line Gene Expression Profiles	1.0	1.55271
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371619
PANK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604795
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6292
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43285
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863079
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
BRD-K77320034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90216
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rare	GeneRIF Biological Term Annotations	1.0	null
studies	GeneRIF Biological Term Annotations	1.0	null
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09702
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5394
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24102
BRD-K58670847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05832
11493696-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68001
androgen and estrogen metabolism	KEGG Pathways	1.0	null
CRCGN014_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13625
Perturb_6668_KO_FGFR1/FGFR3/FGFR4_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K92301463_-666_LOVO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
NCIH322	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47288
membrane region	GO Cellular Component Annotations 2015	1.0	null
BRD-K56107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11655
PIK3C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492419
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072668
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45516
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9627
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
Nauplius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61431
MFAP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00535874
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	3.3946
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9601
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75232
Kudzusaponin SA4	HMDB Metabolites of Enzymes	1.0	null
Etiocholanolone	HMDB Metabolites of Enzymes	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.334242
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87384
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
hsa-miR-2052	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Cauline leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
STARD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604055
hsa-miR-3150b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Testosterone glucuronide	MW Enzyme Metabolite Associations	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863079
TCF12	ENCODE Transcription Factor Targets	1.0	null
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89233
BRD-K09106444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1137
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32245
DMS-53	GDSC Cell Line Gene Expression Profiles	1.0	2.26685
Benign recurrent intrahepatic cholestasis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384013
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00847761
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00631
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_8705_KD_SIRT1_SRP267968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.63857
PMC9035581-HEP4-6-1157-s002.docx-2-Supplementary_Table_S4_List_of_genes_differentially_expressed_between_FOXS1-positive_and_-negative_HCC_cell_lines_FOXS1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-578	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
Blood serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
Lablaboside F	HMDB Metabolites of Enzymes	1.0	null
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
BRD-K63761383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00725
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
ROBO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564634
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59651
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01223
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1244
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71919
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62346
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61813
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06898
HDMYZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16816
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47191
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.575
BRD-K61551681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35271
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57571
MEF2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436715
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23933
BRD-K93516545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42396
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71614
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.349595
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851367
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423054
Cotinine glucuronide	HMDB Metabolites of Enzymes	1.0	null
Wilson disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
SNU13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00763372
BRD-K58534531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03902
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.316
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83436911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70922
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1092
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3698
Common bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
NLRC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00455933
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.267
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1632
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30651
monocarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Testosterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86718
SRSF7_02_02	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.51881
CMK	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93401
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0361
SCH	DepMap CRISPR Gene Dependency	1.0	6.2144
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.979
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6334
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
udp-glycosyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887531
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-386-TCF7L1_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.187277
Estriol	MW Enzyme Metabolite Associations	1.0	null
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17928
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48551
CYP21A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00445158
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041932
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	0.89176
crigler-najjar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.888029
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.830291
TMEM33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00774974
BRD-K88662980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23903
FOSL2	ENCODE Transcription Factor Targets	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917066
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCARA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518011
activities	GeneRIF Biological Term Annotations	1.0	null
Acetaminophen glucuronide	HMDB Metabolites of Enzymes	1.0	null
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Ibuprofen	DrugBank Drug Targets	1.0	null
SIT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633861
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.03641
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11405_KD_RB1_SRP099582	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6624
WT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050019
GP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583011
ORM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573795
BRD-K87000197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13427
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0404
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04058
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.58025
heart	GTEx Tissue Gene Expression Profiles	1.0	1.20379
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79148949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23519
Clara cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
2-Methoxyestrone 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03756
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.03715
Retinyl beta-glucuronide	HMDB Metabolites of Enzymes	1.0	null
caucasiansand	GeneRIF Biological Term Annotations	1.0	null
Perturb_8172_KD_ILF3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.994
Lung adenocarcinoma_LUAD_TCGA-93-8067-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	273.936
MAP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563285
GSE205332_2_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59776
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32206
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.316081
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044441
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03474
BRD-K29543978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81687
SPDEF_01_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.02999
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89226
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1513
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
Amylin receptor complex 3	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
Intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058916
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TXK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520807
BRD-K55884477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39564
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075445
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17017
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.385193
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266069
BRD-K22875057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49034
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8061
RCC-ER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Congenital disorder of glycosylation type IIk	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05034
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
BRD-K98343273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.452
BRD-K41649962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98692
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10873
BRD-K22383829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0532
STAT3	ChEA Transcription Factor Targets	1.0	null
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.9739
Perturb_8069_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.5715
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
FAM20C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523056
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
Bilirubin glucuronide	HMDB Metabolites of Enzymes	1.0	null
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
hsa-miR-216b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
japanesewould	GeneRIF Biological Term Annotations	1.0	null
BRD-K84278600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24726
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05648
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9628
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02839
CCF-STTG1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.134
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80101
Perturb_11446_KD_TMEFF2_SRP302699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.3896
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHOSPHO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808293
BRD-K38403252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0573
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
CRCGN015_MCF10A.TP53.M_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5299
MNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39309
Achyranthoside C	HMDB Metabolites of Enzymes	1.0	null
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
Naproxen	CTD Gene-Chemical Interactions	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489838
BRD-K84707727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72615
residue	GeneRIF Biological Term Annotations	1.0	null
Extrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00722
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14382
Duodenal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
retinoic acid binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K52441396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62854
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3487
11-beta-Hydroxyandrosterone-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
ENTPD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579709
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12045
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75588273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18048
BRD-K92140823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50537
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54084
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364139
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18367
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
BRD-K81952048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92484
Gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.587
BRD-K66214486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54994
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70881
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549377
BRD-K62572662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80971
Secretory trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5581
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
BRD-K55642725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77439
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83607
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49255
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.144
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.85183
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	2.0569
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86718
JHOS4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96371
HEXA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700103
BRD-K79954583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01928
SNU1040	CCLE Cell Line Gene Expression Profiles	1.0	1.90629
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
SRGN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762591
G361	CCLE Cell Line Gene CNV Profiles	1.0	1.32894
Bilirubin	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_3H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15207
LCAT	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K85664064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14317
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365859
Testosterone	HMDB Metabolites of Enzymes	1.0	null
Cholic acid glucuronide	HMDB Metabolites of Enzymes	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN014_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54126
BRD-K47995281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57415
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047296
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69767
BRD-K46239950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75594
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
ZNF75D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74617
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
organic acid binding	GO Molecular Function Annotations 2015	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4967
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6933
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
11-Oxo-androsterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
Fascioliasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
Lung adenocarcinoma_LUAD_TCGA-55-8615-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hearing Loss	HuGE Navigator Gene-Phenotype Associations	1.0	null
endogenous depression	GWASdb SNP-Disease Associations	1.0	0.886521
Camelliasaponin A2	HMDB Metabolites of Enzymes	1.0	null
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0472
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53459
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_up-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10136
BRD-K46726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41958
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	1.3882
EP300	ENCODE Transcription Factor Targets	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
BRD-K12017137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31832
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48191
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58996
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
MEK_OE_GDS1925_165_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Losartan N2-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05602
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.29256
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Primary biliary cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
TIAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568527
anion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71871
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.3829
BRD-K56912308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16373
BRD-K11641139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58155
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
IRX1_01_227	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.30072
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42228
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04058
BRD-K88613983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60247
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16122
NCI-H1869	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fatty Liver	DisGeNET Gene-Disease Associations	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
D-Glucuronic acid	HMDB Metabolites of Enzymes	1.0	null
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10859
Porphyrin metabolism	KEGG Pathways 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5997
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57679
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
TMK1	DepMap CRISPR Gene Dependency	1.0	4.92362
breast cancer; testosterone; estradiol; morphine glucuronidation	GAD Gene-Disease Associations	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.195681
Perturb_8290_KD_PRPF8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6312
Ketoprofen glucuronide	HMDB Metabolites of Enzymes	1.0	null
variation	GeneRIF Biological Term Annotations	1.0	null
BRD-K49039223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34852
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69663
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.19532
TOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00625091
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3689
Chondroitin 4-sulfate	HMDB Metabolites of Enzymes	1.0	null
BRD-K93176491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68892
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAMP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517735
BRD-K58696904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68089
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
BRD-K81881801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54703
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78715
CRCGN011_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0754
starch and sucrose metabolism	KEGG Pathways	1.0	null
hexosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Farnesoid X receptor pathway	WikiPathways Pathways 2024	1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27102
RAD23B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00394515
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41298
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2301
NB17	GDSC Cell Line Gene Expression Profiles	1.0	1.49798
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.707961
SCIMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00493757
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127682
FGA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474262
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3323
hsa-miR-135a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13154
BRD-A12725272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40156
Blood group incompatibility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061478
Root hair tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.254
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2748
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81994
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25385
BRD-K36804307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18989
A-Netherlands-602-2009(H1N1)_30Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39136
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00424
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36769
HNRNPL_02_96	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.38054
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.34542
3-isopropylmalate dehydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5373
CRCGN014_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62285
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54673
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.614
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925263
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.38839
RPMI8402	CCLE Cell Line Gene CNV Profiles	1.0	1.87883
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9474
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1092
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
SN38 glucuronide	HMDB Metabolites of Enzymes	1.0	null
FGGY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603029
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48564
Glycochenodeoxycholic acid 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
U343	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94247
selection	GeneRIF Biological Term Annotations	1.0	null
BRD-K64804596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12837
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992767
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43956
HT55	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27485
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44889
BRD-K09112411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46862
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55395
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
NEK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530403
Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MONOMAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23552
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91553
BRD-A70167453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3033
2-Methoxyestrone 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
BRD-K72296840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44034
BRD-K58155058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25158
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27622
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52445
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35148
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06413
organelle part	GO Cellular Component Annotations 2015	1.0	null
25-Hydroxyvitamin D2 25-(beta-glucuronide)	HMDB Metabolites of Enzymes	1.0	null
Defective UGT1A1 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
Perturb_8125_KD_LARP4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.35794
Gastric ulcer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Tyramine glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34379
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90033
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
BRD-K37760996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76634
SW872	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8756
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894431
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.632335
LN428	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.06762
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14175
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26206
BRD-K72261386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9664
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35775
Benzoyl glucuronide (Benzoic acid)	HMDB Metabolites of Enzymes	1.0	null
Morphine-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Smooth endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
unusual	GeneRIF Biological Term Annotations	1.0	null
YAP_OE_GDS3220_32_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978556
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
BRD-K77787814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26961
bile	GeneRIF Biological Term Annotations	1.0	null
ticarcillin-6146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
balancing	GeneRIF Biological Term Annotations	1.0	null
WNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53765
NDUFA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00412185
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.008
Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pectin	HMDB Metabolites of Enzymes	1.0	null
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07722
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05648
BRD-A20208638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61719
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2192
HT29	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.7214
BB30HNC	DepMap CRISPR Gene Dependency	1.0	2.91161
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-A47513740_calyculin A_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07309
UDP-glycosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
GART	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618764
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34949
CRCGN011_HEPG2_24H:J09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30555
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79554
PL4	DepMap CRISPR Gene Dependency	1.0	7.53604
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49057
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K07756997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57617
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide	HMDB Metabolites of Enzymes	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
ZNF10	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.296601
BRD-K57343972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06962
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol	MW Enzyme Metabolite Associations	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33827
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EPHA7	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7943
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.896905
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3335
NELL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050741
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42792
Hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.447
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16157
BRD-K93747373_HG-5-113-01_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.534647
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.274376
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.403031
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03709
BRD-K79065821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6937
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
BRD-K09663164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85825
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978195
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058429
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055917
Metabolism	Reactome Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20470077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14096
monosaccharide metabolic process	GO Biological Process Annotations 2015	1.0	null
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82039
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33031
BRD-K57084585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12118
Collagen type V trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499223
membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K26351062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83299
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
AR-21909140-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
1-(alpha-Methyl-4-(2-methylpropyl)benzeneacetate)-beta-D-Glucopyranuronic acid	HMDB Metabolites of Enzymes	1.0	null
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84817
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45737
Progressive familial intrahepatic cholestasis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Invasive aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6404
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.500007
BRD-K74537725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2685
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
Thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
KP1NL	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13736
Pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
MTHFD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69258
Gavestinel	DrugBank Drug Targets	1.0	null
Pitcher	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
BRD-A98099470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76552
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
BRD-K08966355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02481
BRD-K58843485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3871
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299601
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16681
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21392
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23983
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Annotation_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Codeine	HMDB Metabolites of Enzymes	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.169
EZH2	ENCODE Transcription Factor Targets	1.0	null
UDP-glucuronic acid	MW Enzyme Metabolite Associations	1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97732674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40197
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
Durupcoside B	HMDB Metabolites of Enzymes	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1212
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.33958
BRD-K53414658_-666_WSUDLCL2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3b_DirectGene_FOXA1-Data3b_Genes_directly_regulated_by_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4446-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GATA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578152
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
BRD-K80044183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24702
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19118372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21532
Perturb_8226_KD_EWSR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.18424
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.742
GOLIM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536319
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FUS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93212
specific developmental disorder	GWASdb SNP-Disease Associations	1.0	0.158829
B-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Metabolism of xenobiotics by cytochrome P450	KEGG Pathways 2026	1.0	null
CFTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697238
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36343
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064976
Hyaluronic acid	HMDB Metabolites of Enzymes	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
Sarcoma_SARC_TCGA-DX-A8BU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16323
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1543
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	1.33042
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
AQP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608873
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46956
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
menarch; obesity; pof - premature ovarian failure; polycystic ovarian syndrome; polycystic ovary syndrome; primary ovarian insufficiency; puberty, delayed; puberty, precocious	GAD Gene-Disease Associations	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.21599
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913316
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7102
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
Defective UGT1A4 causes hyperbilirubinemia	Reactome Pathways 2014	1.0	null
Ardeparin	HMDB Metabolites of Enzymes	1.0	null
SLC22A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666859
Etiocholanolone	MW Enzyme Metabolite Associations	1.0	null
tyrosinemia type i	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.751678
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58574
BRD-K02634083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76957
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
BRD-K13673722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3773
genotypes	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17-beta-Estradiol glucuronide	HMDB Metabolites of Enzymes	1.0	null
gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.765296
BRD-K33462260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80114
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
BRD-K45635721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31621
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.53796
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.539
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22108
IL1RAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00726887
BRD-K89932793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06801
Plant ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64825
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01687
NPTN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00412917
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pparalpha	GeneRIF Biological Term Annotations	1.0	null
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
hsa-miR-1238	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CD160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525735
OR2L13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543858
BRD-K45358679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71217
glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201962
4,4'-hexafluorisopropylidene diphenol	CTD Gene-Chemical Interactions	1.0	null
BRD-K18190982_COT-10b_VCAP_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC2895650__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PID1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527929
Morphine-3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1317
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.581996
BRD-K50931403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3924
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
Glucosephosphate dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05655
BRD-K36464765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38423
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	3.64147
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
WARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512993
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.747
ADGRG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79734
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46554
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3ER-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8038
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
TBP	ENCODE Transcription Factor Targets	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361901
Lung adenocarcinoma_LUAD_TCGA-05-4390-01A-02R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17405
upstream	GeneRIF Biological Term Annotations	1.0	null
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.461261
Chemical carcinogenesis - DNA adducts	KEGG Pathways 2026	1.0	null
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
D-Glucaric acid	HMDB Metabolites of Enzymes	1.0	null
specific learning disability	GWASdb SNP-Phenotype Associations	1.0	0.593884
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMSAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559402
hexosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.9879
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CAL120	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03646
MCCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685961
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81654
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Lennox-Gastaut syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.527
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34985
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
Urea cycle disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
fxr	GeneRIF Biological Term Annotations	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
Polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.579
metabolism of xenobiotics by cytochrome p450	KEGG Pathways	1.0	null
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Polycystic Ovary Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26992703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34124
BRD-K19652287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5362
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45852
bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.114847
ATXN7L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064199
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
BRD-K12132610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04926
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGR1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54877
Enoxaparin	HMDB Metabolites of Enzymes	1.0	null
TBXAS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576556
RXRA	ENCODE Transcription Factor Targets	1.0	null
HSC4	DepMap CRISPR Gene Dependency	1.0	5.31787
BRD-K79753227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08663
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60371
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
Perturb_8448_KD_ABL1_SRP212071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K01417352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56819
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71092
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72328
SLC43A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051094
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	2.50455
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046417
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499615
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6751
CRCGN014_HEPG2_3H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4695
HOXB7_01_169	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.68011
(3a,5b,7a,12a)-24-[(carboxymethyl)amino]-1,12-dihydroxy-24-oxocholan-3-yl-b-D-Glucopyranosiduronic acid	HMDB Metabolites of Enzymes	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925263
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.45287
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.91301
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4266
IL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08707
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1564
single-organism carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCN7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586417
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49399
FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.36504
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
gilbert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16606
Isovalerylglucuronide	HMDB Metabolites of Enzymes	1.0	null
Respiratory mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Epinephrine glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K88812688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53291
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
BRD-K37515001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43647
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
17-alpha-Estradiol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
PBX3	ENCODE Transcription Factor Targets	1.0	null
Congenital hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.945
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36081737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58728
Defective GGT1 causes Glutathionuria (GLUTH)	Reactome Pathways 2014	1.0	null
Larsen-like syndrome B3GAT3 type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
Fetal serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.854
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.273
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1269
3-Methoxy-4-hydroxyphenylglycol glucuronide	HMDB Metabolites of Enzymes	1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.300704
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.02858
PUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83635
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.58134
SN-38	HMDB Metabolites of Enzymes	1.0	null
MPL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00547243
Blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.508
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07348252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97775
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	294.74
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
EPHB6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568557
SNU-620 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
Quercetin-4'-glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2196
FTC238	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16765
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
NR2F2	ENCODE Transcription Factor Targets	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.999805
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)	Reactome Pathways 2014	1.0	null
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3904
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pericardium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45146
Crigler-Najjar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.905
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K28079391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74299
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
af1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.456
AGS	Achilles Cell Line Gene Essentiality Profiles	1.0	1.40942
NNAL-N-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Melilotussaponin O1	HMDB Metabolites of Enzymes	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
Perturb_8199_KD_CALR_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.6685
BRD-K19766710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80795
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47474571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44641
BRD-K00566460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23827
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76724
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08953
ZR-75-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
BRD-K61520618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8471
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5008
IQSEC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00443025
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18747
6-Hydroxy-5-methoxyindole glucuronide	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.39626
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7514
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195279
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286381
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043156
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11807
Perturb_15175_KD_LOC157273_SRP238261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53571
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.14989
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34213
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40741
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
KCNJ14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00664262
Rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95285
Flurbiprofen	DrugBank Drug Targets	1.0	null
UDP	MW Enzyme Metabolite Associations	1.0	null
BRD-K76942055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25351
Perturb_11392_KD_BUB3_SRP292689	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
HNRNPLL_02_125	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.82299
PMC3573348__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.359
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269521
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07538
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.296601
Cholestasis	CTD Gene-Disease Associations	1.0	1.09083
HEPG2	CCLE Cell Line Gene Expression Profiles	1.0	1.43284
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2339
Testosterone sulfate	HMDB Metabolites of Enzymes	1.0	null
Cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
BRD-K48912618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35504
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)	Reactome Pathways 2014	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6911
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23941
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.99639
drug-related genes	GAD Gene-Disease Associations	1.0	null
PK45H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78709
Estriol	HMDB Metabolites of Enzymes	1.0	null
Morphine	DrugBank Drug Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7946
Fondaparinux sodium	HMDB Metabolites of Enzymes	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.195681
BRD-K23430114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41684
GSE207301,GSE207303_0_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
Perturb_8456_KO_FGFR3/FGFR4_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.352
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97465
kidney	HPA Tissue Protein Expression Profiles	1.0	1.84329
Water	HMDB Metabolites of Enzymes	1.0	null
DLD1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.49041
GHRHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546856
BRD-K25284184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34401
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.625
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07373
BRD-K31195910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18464
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
BRD-A05635986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61499
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61958
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35766
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354455
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71671
Myrosin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7068
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
Codeine	DrugBank Drug Targets	1.0	null
Thioglucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58266
FGFR3_knockdown_174_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.74299
EOL1	CCLE Cell Line Gene CNV Profiles	1.0	1.40162
Nascent polypeptide-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.253
Testosterone	MW Enzyme Metabolite Associations	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
SLC19A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634214
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
SDHB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480299
isoprenoid binding	GO Molecular Function Annotations 2015	1.0	null
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.83097
biliary atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.320454
BRD-A19500257_geldanamycin_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.620621
BRD-K42899395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02571
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043016
BRD-K48332223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10175
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872136
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138612
BRD-K07276022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94357
Durupcoside A	HMDB Metabolites of Enzymes	1.0	null
Hepatic vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075508
NSDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02573
BRD-K50599016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6413
lipid binding	GO Molecular Function Annotations 2015	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061112
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80519
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06304
GBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538495
Medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
Perturb_8457_KO_FGFR4_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.45401
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
U251MG	CCLE Cell Line Gene CNV Profiles	1.0	2.40853
BRD-K21119095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3338
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09499853_KU 0060648 trihydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10922
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637234
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32668
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899918
esophageal	GeneRIF Biological Term Annotations	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43677
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87401
SNU886	CCLE Cell Line Gene Expression Profiles	1.0	1.47557
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
Prostate adenocarcinoma_PRAD_TCGA-VP-A87H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69759
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2368
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2082
Neonatal jaundice	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.713
BRD-K85741537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48276
BRD-K39449072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09628
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.65
PMC6289345__F5	PFOCR Pathway Figure Associations 2024	1.0	null
biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.622967
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Drug ADME	Reactome Pathways 2024	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3805
VPREB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00670672
TEAD4	ENCODE Transcription Factor Targets	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852608
RAD21	ENCODE Transcription Factor Targets	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92937
Calenduloside H	HMDB Metabolites of Enzymes	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE138939_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ugt2b72b4	GeneRIF Biological Term Annotations	1.0	null
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	GAD High Level Gene-Disease Associations	1.0	0.300704
response to organic substance	GO Biological Process Annotations 2015	1.0	null
lipid catabolic process	GO Biological Process Annotations 2015	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1193
Rhizome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.54911
BRD-K03901181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44833
hepatocytes	GeneRIF Biological Term Annotations	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9627
steroid metabolic process	GO Biological Process Annotations 2015	1.0	null
Stevens-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
genotyping	GeneRIF Biological Term Annotations	1.0	null
ASIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554412
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46327
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86076
Gallbladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20437312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03586
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
other	GAD High Level Gene-Disease Associations	1.0	0.295739
BRD-K74656131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00419
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00329
BRD-K49132774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05675
risk	GeneRIF Biological Term Annotations	1.0	null
JUND_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hearing loss	GAD Gene-Disease Associations	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5086
Hepatoma HLE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.80271
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2177
monocarboxylic acid binding	GO Molecular Function Annotations 2025	1.0	null
ZNF461	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42581
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85105
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93153656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35098
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47317
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9347
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0882
Vascular endothelial glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.166
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.637
Endocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22012
Codeine and morphine metabolism	WikiPathways Pathways 2024	1.0	null
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18887
mental depression	GWASdb SNP-Disease Associations	1.0	0.463438
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dyslexia	GWASdb SNP-Phenotype Associations	1.0	0.593884
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.76275
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K10989535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20043
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07547
CAMKK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475714
Fever	CTD Gene-Disease Associations	1.0	1.19704
BOP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521498
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	1.55032
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20511
Perturb_8097_KD_SUCLG1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.75801
BRD-K28467941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93223
BRD-K49526793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12763
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.381
BRD-K44371786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99039
HLE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88214
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.583621
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.974598
BRD-K02809100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45977
UDP-glycosyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K27172015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20507
wilson disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162707
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
BRD-K23703519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18719
KYAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521964
glucuronate metabolic process	GO Biological Process Annotations 2015	1.0	null
AIRE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484495
BRD-K52231520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22225
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060686
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.704
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
IFNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056574
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11774
BRD-K40228963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63693
Heparin	HMDB Metabolites of Enzymes	1.0	null
Colon transversum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
Biological oxidations	Reactome Pathways 2014	1.0	null
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.48682
Cholestasis	DisGeNET Gene-Disease Associations	1.0	null
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.06952
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09403
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.556
BRD-K69291887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74323
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992767
Etiocholanolone glucuronide	HMDB Metabolites of Enzymes	1.0	null
UDP-glucuronosyl/UDP-glucosyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17087
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
organelle	GO Cellular Component Annotations 2015	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
PRMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00432576
Sandosaponin A	HMDB Metabolites of Enzymes	1.0	null
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
EIF4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066747
BRD-K47572485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53591
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
Puberty, Delayed	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K69699301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08879
Portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61852
MFE296	DepMap CRISPR Gene Dependency	1.0	8.04194
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460348
Protein kinase 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
SP3_01_290	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.58866
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.523982
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83941
6-Dehydrotestosterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42787
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
BRD-K90901488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31404
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75335
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0989
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873921
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05141
breast cancer	GAD Gene-Disease Associations	1.0	null
Carcinoma, Squamous Cell	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3856
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04204
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74627
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74351
BRD-K24930745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82234
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.0018
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.32162
Bacteremia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52489
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
trans-3-Hydroxycotinine glucuronide	HMDB Metabolites of Enzymes	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837275
Bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
MMRN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587527
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
Gilbert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.075
L3MBTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7246
Betavulgaroside IV	HMDB Metabolites of Enzymes	1.0	null
MHHNB11	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4949
GPA33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480584
TENM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00350879
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.0189
hsa-miR-4509	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K61287439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55246
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
splicing	GeneRIF Biological Term Annotations	1.0	null
YAP1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86718
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
BRD-K15474464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09049
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
BRD-K08408085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.653
common	GeneRIF Biological Term Annotations	1.0	null
Perturb_12918_KD_C1orf186_SRP411666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.7448
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64031
Liver bud hepatic cell_Liver_Human	CellMarker Gene-Cell Type Associations	1.0	null
Intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
BRD-K14087001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30727
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28156
gallbladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.02187
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
KMT5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046434
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
BRD-K43535770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99246
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48622
porphyrin and chlorophyll metabolism	KEGG Pathways	1.0	null
Perturb_13704_KD_SMARCA2_SRP247495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.30012
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57176
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38376
thioredoxin-disulfide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
IL36G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459475
RTEL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628241
DPPA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558454
ABITRAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36638
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74694052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76022
VCAP	CCLE Cell Line Gene Expression Profiles	1.0	1.49919
useful	GeneRIF Biological Term Annotations	1.0	null
Kupffer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
PMC7188667__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K92012390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14517
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19595
SNU761	CCLE Cell Line Gene Expression Profiles	1.0	1.64172
SMAD2_01_248	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.80049
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
hsa-miR-3150a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
YY2_KD_GDS3788_490_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166177
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5141
LI7	CCLE Cell Line Gene Expression Profiles	1.0	1.67413
BRD-K39318389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1005
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7337
Estrone glucuronide	HMDB Metabolites of Enzymes	1.0	null
2-Methoxyestrone	HMDB Metabolites of Enzymes	1.0	null
COQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32168
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
Octanoylglucuronide	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02435
FOXP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514123
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FEZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00822133
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
intermediate-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.193719
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.803
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2182
BRD-K39978929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05001
Propionic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
Congenital dyserythropoietic anemia type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18505
BRD-K44458042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21873
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834001
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
GRB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6747
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090035
calcium:proton antiporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
STAT3	ENCODE Transcription Factor Targets	1.0	null
FCER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567106
Dopamine glucuronide	HMDB Metabolites of Enzymes	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Estriol-16-Glucuronide	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.66861
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.11632
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
hsa-miR-2054	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
retinoid binding	GO Molecular Function Annotations 2023	1.0	null
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
steroid catabolic process	GO Biological Process Annotations 2015	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40349
BRD-K94744294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22221
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05753
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
22RV1	CCLE Cell Line Gene Expression Profiles	1.0	1.52396
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K57011718_UK 356618_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6706
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28471
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K23192422_L-6307_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.119807
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.16137
Terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
muricholic acid	CTD Gene-Chemical Interactions	1.0	null
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0479
BRD-K23503923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10421
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28226
Estrone	MW Enzyme Metabolite Associations	1.0	null
xenobiotic metabolic process	GO Biological Process Annotations 2015	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4978
BRD-K95422706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03023
Cholelithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42671
Edema	CTD Gene-Disease Associations	1.0	1.46909
Silenoside B	HMDB Metabolites of Enzymes	1.0	null
BRD-K31801624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35547
Desbuquois dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Drug metabolism - cytochrome P450	KEGG Pathways 2026	1.0	null
Oligosaccharyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33046
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K90151990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1039
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
LNCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
Glomerulonephritis, Membranous	CTD Gene-Disease Associations	1.0	1.04352
P-388 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
BRD-A21877498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33995
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortolone-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
lncap cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418861
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myelomonocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44275
BRD-K80290360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20573
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2163
LCT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502571
CRCGN008_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53475
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87093
16-alpha,17-beta-estriol 17-beta-D-glucuronide	HMDB Metabolites of Enzymes	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00359952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64717
transferase activity, transferring hexosyl groups	GO Molecular Function Annotations 2015	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913316
TSPOAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507771
PRPF4_02_128	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.81651
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5199
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.099102
NFIC	ENCODE Transcription Factor Targets	1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78948
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36777
BRD-K01285236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54863
Phenethylamine glucuronide	HMDB Metabolites of Enzymes	1.0	null
SLC16A10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689666
C8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592873
BRD-K65824451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21884
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.335412
Perturb_12540_KO|OE_FBXO11|FBXO11_SRP278534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
liver	HPA Tissue Gene Expression Profiles	1.0	2.24804
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
japanese	GeneRIF Biological Term Annotations	1.0	null
CTDK-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
4-aminobutyrate transaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
Canagliflozin	DrugBank Drug Targets	1.0	null
UDP-L-iduronate	HMDB Metabolites of Enzymes	1.0	null
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00414884
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01308
SHISA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467185
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.989
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16484
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	274.629
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
3M complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
HEP3B217	CCLE Cell Line Gene CNV Profiles	1.0	1.97892
BRD-K31992830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56331
FOXA2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retinoid binding	GO Molecular Function Annotations 2015	1.0	null
farnesoid	GeneRIF Biological Term Annotations	1.0	null
Plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.881
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99393
endoplasmic reticulum	LOCATE Curated Protein Localization Annotations	1.0	null
TK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.91574
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
CCRF-CEM	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42599
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39053
3-alpha,20-alpha-Dihydroxy-5-beta-pregnane 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42968343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38612
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
Disease	Reactome Pathways 2014	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
BRD-K50210179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3221
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viral hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
KYAE1	DepMap CRISPR Gene Dependency	1.0	4.7844
RRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21255
HIF1A_01_156	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.41373
lung	HPA Tissue Gene Expression Profiles	1.0	0.826159
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7162
CXCR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704958
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8174_KD_PABPC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.47393
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.810073
Androsterone	MW Enzyme Metabolite Associations	1.0	null
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5802
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44223
Nicotine glucuronide	HMDB Metabolites of Enzymes	1.0	null
TCF12_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8306
HSPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3176
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061267
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.91
CRCGN010_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15444
NCI-H82	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4473
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3997
Morphine-6-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Gall bladder epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.57862
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
BRD-K32983008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53028
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
BRD-K68041793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51231
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.448054
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0402
Nuclear aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MDAMB415	CCLE Cell Line Gene Expression Profiles	1.0	2.25279
Estriol 3-sulfate 16-glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88889
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826447
HCC70	DepMap CRISPR Gene Dependency	1.0	2.16622
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14809
developmental disorder of mental health	GWASdb SNP-Disease Associations	1.0	0.131871
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87651
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30552
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Silenoside C	HMDB Metabolites of Enzymes	1.0	null
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22318
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38672
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15024
BRD-K04371719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06106
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54782
ZBTB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15703
Choledocholithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
TSPAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.771
SNU-1040	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
Perturb_8458_KO_KLB_SRP386785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
modulates	GeneRIF Biological Term Annotations	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	3.22542
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.7044
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2303
HEC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.50937
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	13.3137
BRD-K89770910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6375
Glucuronic acid	MW Enzyme Metabolite Associations	1.0	null
Perturb_8089_KD_HNRNPA2B1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.35835
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.277
Digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.833
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55192
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880837
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5059
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4551
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00337
Hydroxycotinine	HMDB Metabolites of Enzymes	1.0	null
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30468
BRD-K65829768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15197
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39762
fascioliasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.949936
CAL-120	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03832
glutamyl-trna(gln) amidotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.868126
Inflammatory bowel disease 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
BRD-K58944125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32199
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18652
bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.095218
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.47171
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K93561942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96219
JUND	ENCODE Transcription Factor Targets	1.0	null
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
BRD-K57059449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28093
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62894
PC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8254
SOX2_Deficiency_GDS4853_321_human_AZ-521 gastric cancer (GC) cell line - 18 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30777
SF767	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07372
Galacturonic acid	HMDB Metabolites of Enzymes	1.0	null
carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
induces	GeneRIF Biological Term Annotations	1.0	null
BRD-K32146668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7083
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.746798
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15144
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDKN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18954
17-beta-Estradiol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
cellular glucuronidation	GO Biological Process Annotations 2023	1.0	null
U87MG	DepMap CRISPR Gene Dependency	1.0	2.43141
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.71343
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27606
mammographic breast density	GAD Gene-Disease Associations	1.0	null
BRD-K56258950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19525
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Pectic acid	HMDB Metabolites of Enzymes	1.0	null
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
flavonoid glucuronidation	GO Biological Process Annotations 2015	1.0	null
BRD-K57014767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27158
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01569
organic cyclic compound catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
2-Methoxy-estradiol-17b 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60176
Jaceidin 4'-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.46
BRD-K23164928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70814
Parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86499
PRKD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526765
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91596
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02569
BRD-K50600207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03961
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.8276
iec-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.473869
SAMD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461157
BRD-K20942146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37155
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.39626
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.66071
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BRD-K32702774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07186
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2291
Progressive familial intrahepatic cholestasis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
PMC6545035-12943_2019_1031_MOESM7_ESM.xlsx-Sheet1-Supplementary_table_5_The_significant_reduced_genes_in_TET1_knockdown_cells_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
familial adenomatous polyposis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213959
reading disorder	GWASdb SNP-Disease Associations	1.0	0.441801
ARHGAP25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597459
cellular response to organic substance	GO Biological Process Annotations 2015	1.0	null
Diabetic ketoacidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
sevoflurane_homo sapiens_gpl570_gds2772	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.91383
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49057
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GS-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HuH-7	GDSC Cell Line Gene Expression Profiles	1.0	2.53544
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pollen tube tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94386
BRD-K15188108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53232
Hypertrophy	CTD Gene-Disease Associations	1.0	1.03009
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	2.40874
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062931
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
squamous	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-516a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60825
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.63979
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extensive	GeneRIF Biological Term Annotations	1.0	null
CSNK2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440914
RAB3A	MSigDB Cancer Gene Co-expression Modules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99513
Cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456442
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.54905
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68072222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20115
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35240878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96522
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186708
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35263
BRD-K92849826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61029
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150238
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.35
Chemical carcinogenesis - receptor activation	KEGG Pathways 2026	1.0	null
glucuronosyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82024
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18312
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39511
ALL-PO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0572
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
CFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491687
Glucuronidation	Reactome Pathways 2024	1.0	null
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68575
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913316
Perturb_11363_KD_TMEFF2_SRP302699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6324
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.727007
BRD-K08259535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18676
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.734
BRD-K32170456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09351
Camelliasaponin A1	HMDB Metabolites of Enzymes	1.0	null
BRD-K64748422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78715
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91646
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apical tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
cholelithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2369
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09916
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.924
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05721
BRD-K35681049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38637
BRD-A98208100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82386
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318635
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36686
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04942
IFI6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00440807
caco-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.645695
PR-Mel cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59472
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201635
liver	GTEx Tissue Gene Expression Profiles	1.0	2.18987
Trichloroethanol glucuronide	HMDB Metabolites of Enzymes	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00472
estrogen catabolic process	GO Biological Process Annotations 2015	1.0	null
Colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.747
BRD-K47285393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35017
BRD-K60692685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08863
Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14570970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97998
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13526564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43654
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31571
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00922
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.657234
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08449
BRD-K87159315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19993
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
U138	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.907293
Iduronic acid	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_3H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1662
THUMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46398
KLHL14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695036
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86718
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
Mucormycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
Xanthan	HMDB Metabolites of Enzymes	1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1463
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
decreased	GeneRIF Biological Term Annotations	1.0	null
ACTR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00355452
BRD-K95007662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60428
estrogen metabolic process	GO Biological Process Annotations 2025	1.0	null
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57696
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67841
Aldosterone 18-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
Priapism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-353-FERD3L_FERD3L	Rummagene Transcription Factor Associations 2026	1.0	null
Dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Bilirubin	MW Enzyme Metabolite Associations	1.0	null
CTDNEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78223
Puberty, Precocious	HuGE Navigator Gene-Phenotype Associations	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.85
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68418
MAZ	ENCODE Transcription Factor Targets	1.0	null
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90579
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-453 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
ost-alpha/ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.858933
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14105
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
TTI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00788996
Alginic acid	HMDB Metabolites of Enzymes	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05753
SNB75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAP4K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479018
CSNK1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00417566
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.912262
disease	GWASdb SNP-Disease Associations	1.0	0.028444
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)	Reactome Pathways 2014	1.0	null
786-0	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93617
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63961
BRD-K63065496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07161
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17771
Gravid adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
BRD-K21662756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22099
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	2.65535
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Portal hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2881
APOBEC3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590213
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05189
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.36061
Lablaboside D	HMDB Metabolites of Enzymes	1.0	null
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
Perturb_8018_KO_PXR_SRP257678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TP53BP1_KD_GSE54268_670_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863079
Spondyloepimetaphyseal dysplasia with joint laxity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37368
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.742
BRD-K48276655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07771
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71403
CPS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00485336
BRD-K23333192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.371
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1608
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K50216176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43374
Proteinuria	CTD Gene-Disease Associations	1.0	1.24024
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
TP63	ChEA Transcription Factor Targets	1.0	null
BRD-K58220038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54637
BRD-K57489406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08513
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.60763
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	341.328
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870318
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37713
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80697
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3693
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
HNF1B_OE_GDS1499_253_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2BC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657561
BRD-K87140555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05907
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.896
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06697
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859355
Metapathway biotransformation Phase I and II	WikiPathways Pathways 2024	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colorectal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
carvedilol	CTD Gene-Chemical Interactions	1.0	null
PUS10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560461
Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.50458
Fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.881
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04533
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851367
Estradiol-17alpha 3-D-glucuronoside	HMDB Metabolites of Enzymes	1.0	null
Digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
very-low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.298455
BRD-K22610244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06481
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78191
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0629
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.799791
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.578494
JUN	ENCODE Transcription Factor Targets	1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
miR-124_OE_GDS2657_771_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060751
NME6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562289
CDH6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00442864
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11743
IGF1R-20145208-DFB-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neonatal abstinence syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49197
BRD-K49552510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0573
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61726
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53862
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5982
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.636785
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042137
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
Neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.07
N2-Galacturonyl-L-lysine	HMDB Metabolites of Enzymes	1.0	null
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4821
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50466
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16126
MDCK-MDR1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449194
BRD-K68758594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34452
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
BRD-K73831263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43182
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15321
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26006
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61916
iodixanol-3023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Androsterone 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Primary sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
BRD-K85887470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29435
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34192219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59082
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524847
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76738405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23027
BRD-K80593371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34072
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.45485
Estriol	CTD Gene-Chemical Interactions	1.0	null
CLCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0076803
SBK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0076942
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0806
BRD-K28448768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17412
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
BRD-K56691168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27204
Estrone 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
BRD-K16503119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16756
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PMC3597092__F3	PFOCR Pathway Figure Associations 2023	1.0	null
JUND_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
PCI4B	DepMap CRISPR Gene Dependency	1.0	9.94163
(23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)	HMDB Metabolites of Enzymes	1.0	null
MAPK14_knockdown_139_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.30327
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.38039
MOG-G-UVW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
haplotypes	GeneRIF Biological Term Annotations	1.0	null
Metapathway biotransformation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
BRD-K68435627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33709
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
BRD-K91905575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03744
Memory Disorders	CTD Gene-Disease Associations	1.0	1.09716
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97676
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9305
Estriol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37957
Hepa-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.239
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
Lithocholate 3-O-glucuronide	HMDB Metabolites of Enzymes	1.0	null
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
Perturb_8377_KD_MAGEA3_ERP120445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.897
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938571
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15342
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18828
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87154
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32142
BRD-K93894185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09929
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.127
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4853
adenomatous polyposis coli; duodenal neoplasms	GAD Gene-Disease Associations	1.0	null
TRDMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00734397
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
SMARCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00668095
Endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.736
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30488
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18747
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74828
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05471
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2871
BRD-K58863194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07268
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K57575504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35443
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.471
BRD-K45663146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14816
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41931
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.693
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
PMC3573348__F5	PFOCR Pathway Figure Associations 2023	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50911
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
Rough endoplasmic reticulum lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
SP110	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061741
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54036
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78095
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86718
BRD-K93601851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27955
BRD-K57195030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13712
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
OAZ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054031
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18721
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
g.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
BRD-K97588749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52953
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
Cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	2.09448
Benign recurrent intrahepatic cholestasis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
cyclopenthiazide-4229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.559
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28581
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36427
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
BRD-K66655211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36723
flavonoid metabolic process	GO Biological Process Annotations 2015	1.0	null
CESS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12711
Silenoside A	HMDB Metabolites of Enzymes	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.935103
Hyperplasia	CTD Gene-Disease Associations	1.0	1.17067
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hep-G2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.884
GATA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28351
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10576
hormone catabolic process	GO Biological Process Annotations 2015	1.0	null
Estradiol	HMDB Metabolites of Enzymes	1.0	null
POLH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00648264
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC2895650__F1	PFOCR Pathway Figure Associations 2023	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.41683
2-Methoxy-17beta-estradiol	MW Enzyme Metabolite Associations	1.0	null
NO11	DepMap CRISPR Gene Dependency	1.0	2.19273
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Galactaric acid	HMDB Metabolites of Enzymes	1.0	null
BRD-K82667180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25291
DTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6097
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98208
DCC	MSigDB Cancer Gene Co-expression Modules	1.0	null
Hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.996
BRD-K23393260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57422
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47055
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.600479
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72991
FOS	ENCODE Transcription Factor Targets	1.0	null
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65918
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11394
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31087
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
gastrointestinal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174093
learning disability	GWASdb SNP-Disease Associations	1.0	0.374199
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.628697
NCIH1650	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.55631
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.853825
PMC3597092__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38813
tyrosinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.50459
Nasopharyngitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49015
Withdrawal disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.54915
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5592
SELENOM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572907
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
BRD-K22135724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42019
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.85
bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574816
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.20654
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.174
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00722
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97601
RNASE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00846172
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
MBD4	ENCODE Transcription Factor Targets	1.0	null
BRD-K56334280_S1367_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06481
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2192
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
BRD-K53748177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28208
transferase activity	GO Molecular Function Annotations 2015	1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94305
COLO-205	GDSC Cell Line Gene Expression Profiles	1.0	1.80241
Brain capillary endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KE-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
BRD-K23763017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09699
Amaranthin	HMDB Metabolites of Enzymes	1.0	null
v-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.997166
cellular hormone metabolic process	GO Biological Process Annotations 2015	1.0	null
Berry	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
CRCGN015_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05151
BRD-K57687960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0131
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.268603
FRK	MSigDB Cancer Gene Co-expression Modules	1.0	null
chr4_69557082_C_T_b38	GTEx eQTL 2025	1.0	6.88728
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01877
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17-Hydroxyandrostane-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K48195722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82845
colo792	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
LCORL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23731
single-organism process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88218
hepatoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.624927
MYC	ENCODE Transcription Factor Targets	1.0	null
bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.786803
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851367
MCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00404115
BRD-K57688676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67859
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99518
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
2,8-Dihydroxyquinoline-beta-D-glucuronide 	HMDB Metabolites of Enzymes	1.0	null
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
3-alpha-Androstanediol glucuronide	HMDB Metabolites of Enzymes	1.0	null
TMEM258	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597264
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
BRD-K77345736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27302
BRD-K02827191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60921
BRD-K69808609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05385
cellular glucuronidation	GO Biological Process Annotations 2015	1.0	null
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Fiddlehead	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08644
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4401
BRD-K03848296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25478
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QQ-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043729
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5854-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2145
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06269
beta-D-Glucuronoside	MW Enzyme Metabolite Associations	1.0	null
BRD-K78249980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65726
BRD-K04930806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03108
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CYP4F2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564087
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04194
EGR1	ChEA Transcription Factor Targets	1.0	null
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.72491
BRD-K98089885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20905
Casparian strip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	2.03234
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.937
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10799
BRD-K27754030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00191
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93835
NCI-H1755	GDSC Cell Line Gene Expression Profiles	1.0	2.04345
Colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.756
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.41106
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45343
vivo	GeneRIF Biological Term Annotations	1.0	null
PEO4	DepMap CRISPR Gene Dependency	1.0	5.17467
C2BBE1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.84868
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98686
Liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.857
BRAF_knockdown_193_GSE5481	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63614
icSARS CoV_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70405
Glucaric acid	HMDB Metabolites of Enzymes	1.0	null
Perturb_8178_KD_SART3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.37341
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.126364
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43132
Flurbiprofen	CTD Gene-Chemical Interactions	1.0	null
Perturb_15370_KD_TP53_SRP294453	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642346
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42591
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16883
BRD-K64418159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09632
Farnesol	CTD Gene-Chemical Interactions	1.0	null
BRD-K87640319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0764
11-Hydroxyprogesterone 11-glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K99122228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54139
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
Median body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47065
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
Prostate adenocarcinoma_PRAD_TCGA-CH-5772-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54111001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00655
Pentose and glucuronate interconversions	KEGG Pathways 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69350885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19237
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.79972
CA5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639919
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29437
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.997
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
SEMA3E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00707169
Vitamin D2 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Estriol-17-glucuronide	HMDB Metabolites of Enzymes	1.0	null
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
response to stimulus	GO Biological Process Annotations 2015	1.0	null
LOVO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.4208
BRD-K06157545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03952
HDAC2	ENCODE Transcription Factor Targets	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240148
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chr4_69539171_C_A_b38	GTEx eQTL 2025	1.0	3.59266
ranirestat	CTD Gene-Chemical Interactions	1.0	null
BMPR2	MSigDB Cancer Gene Co-expression Modules	1.0	null
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01286
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419623
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1772
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992767
(3a,5b,7a)-23-Carboxy-7-hydroxy-24-norcholan-3-yl-b-D-Glucopyranosiduronic acid	HMDB Metabolites of Enzymes	1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
Perturb_11395_KD_YAP1_SRP333272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.3283
Bile ductule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Retinol metabolism	KEGG Pathways 2026	1.0	null
pralidoxim	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42997
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.24912
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02737
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	1.43539
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2267
PMC6289345__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Thyroxine glucuronide	HMDB Metabolites of Enzymes	1.0	null
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06507
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59052
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
BRD-K90040724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01278
BRD-K55072060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67025
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24568
hsa-miR-649	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
17131328-TableII	GeneSigDB Published Gene Signatures	1.0	null
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	2.02512
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
BRD-A46631350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1556
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.98573
africansbutstill	GeneRIF Biological Term Annotations	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42277
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.95079
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167487
Pharate pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
patu8988s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52272
hsa-miR-513b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PSKH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491461
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6056
BRD-K42126874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19477
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.94974
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)	Reactome Pathways 2014	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.940776
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dextrorphan O-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79498
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.13
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.46316
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.4725
BRD-K35209334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12223
V-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
miR-124_OE_GDS2657_770_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
NUGGC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00727458
MAFK	ENCODE Transcription Factor Targets	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
Sexual dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
3-alpha-hydroxy-5-alpha-androstane-17-one 3-D-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
PLCG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484439
BRD-K61439332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63788
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
TRIM46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00655936
G6PC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590525
MCUR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00439169
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
BRD-K74870161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20138
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16167
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37316
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K45714931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06451
NMUR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601343
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4181
FCRL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00692503
Perturb_8222_KD_AKAP8L_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.38401
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.61077
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068654
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8385_KD_USP22_SRP213120	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2674
Chondroitin sulfate	HMDB Metabolites of Enzymes	1.0	null
carboxylic acid binding	GO Molecular Function Annotations 2015	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030933
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9599
chr4_69527962_G_A_b38	GTEx eQTL 2025	1.0	9.52628
Hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.89
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.302
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47356
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
aortic root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.443731
RH30	CCLE Cell Line Gene Expression Profiles	1.0	1.45173
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8544
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36625
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47034
BRD-K03089783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44746
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70969
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83771
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12432
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
TUBB6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00402182
BRD-K54212583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51793
PCI6A	DepMap CRISPR Gene Dependency	1.0	9.17561
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
SIN3A	ENCODE Transcription Factor Targets	1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4925
4-Hydroxyandrostenedione glucuronide	HMDB Metabolites of Enzymes	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.133
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15384
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28213
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16259
15637295-Table5	GeneSigDB Published Gene Signatures	1.0	null
DMS53	CCLE Cell Line Gene Expression Profiles	1.0	1.84965
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13514097_S1120_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
steroid metabolic process	GO Biological Process Annotations 2025	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81849
Sarcoma_SARC_TCGA-N1-A6IA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325916
ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Benign recurrent intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28655
BRD-A44990218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38427
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6208
H2AC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13823
Xylem parenchyma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
BTN1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486693
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.163372
IL9	MSigDB Cancer Gene Co-expression Modules	1.0	null
cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04225
BRD-K06091213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68797
BRD-K81592842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07192
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18384
HCT116	DepMap CRISPR Gene Dependency	1.0	6.67996
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acetolactate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692902
STAT5A	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-104-C11orf9_MYRF	Rummagene Transcription Factor Associations 2026	1.0	null
S1PR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575823
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47005
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGALS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558698
TEK_knockdown_122_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70117
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
highly	GeneRIF Biological Term Annotations	1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
folic acid_homo sapiens_gpl2700_gds3656	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2098
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60934
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	13.3357
RFX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K43106305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17991
LMSU	CCLE Cell Line Gene CNV Profiles	-1.0	-3.04731
ATF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050703
Alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.395
ugt2b4	GeneRIF Biological Term Annotations	1.0	null
IL1R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049092
GCSH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500049
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08701
presence	GeneRIF Biological Term Annotations	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	0.928902
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:A24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51799
Hepa-RG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
Morphine	HMDB Metabolites of Enzymes	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5662
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54317
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
RMGI	Achilles Cell Line Gene Essentiality Profiles	1.0	1.67241
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3781
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.5118
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
Heparan sulfate	HMDB Metabolites of Enzymes	1.0	null
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24342
Vacuolar proton-transporting V-type ATPase, V1 domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131835
SIRT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453104
retinoic acid binding	GO Molecular Function Annotations 2025	1.0	null
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
19061838-TableS7	GeneSigDB Published Gene Signatures	1.0	null
inhibits	GeneRIF Biological Term Annotations	1.0	null
Morphine-6-glucuronide	MW Enzyme Metabolite Associations	1.0	null
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64407
25-Hydroxyvitamin D2-25-glucuronide	HMDB Metabolites of Enzymes	1.0	null
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
Rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
HNF4G	ENCODE Transcription Factor Targets	1.0	null
Achyranthoside D	HMDB Metabolites of Enzymes	1.0	null
deoxynivalenol	CTD Gene-Chemical Interactions	1.0	null
RARA_01_51	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.95936
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61369
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
CCL17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664092
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943453
biological regulation	GO Biological Process Annotations 2015	1.0	null
ATR_knockdown_140_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29156
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66064
Mucositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
Apical plasma membrane urothelial plaque	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
BRD-K47063692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42005
Colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.644586
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.97166
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.856457
doxorubicin_homo sapiens_gpl570_gse11940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53110645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33858
p-Cresol glucuronide	HMDB Metabolites of Enzymes	1.0	null
transcripts	GeneRIF Biological Term Annotations	1.0	null
BRD-K65203256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27412
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL8428 (SCFD1)	NURSA Protein Complexes	1.0	null
Cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.813
Glycoprotein network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.257
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0576
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88274
IKZF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057735
BRD-K49664555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70375
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24354
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80812
Intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.85
single-organism catabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_11416_KD_RB1_SRP271262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087149
Malignant tumor of pancreas_saliva_GSE14245	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.54684
OXER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006009
BRD-K49325049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99738
SYK_KD_GDS3609_441_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PLA2R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555518
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870318
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36738
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.54111
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.868783
MDA-MB-453	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41856
Cholestane-3,7,12,25-tetrol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Dehydroisoandrosterone 3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.033
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.473
PTP4A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591996
FEN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571591
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Unnamed_2_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
Fetalliver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042434
BRD-K78625574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11421
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863079
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.335
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37457
Biliary atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
BRD-K69109808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37942
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95923
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22113
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.0234
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.169909
intestinal benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280439
Bilirubin diglucuronide	HMDB Metabolites of Enzymes	1.0	null
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19232
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87401
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.345
BRD-K47984776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08866
Hypertension	CTD Gene-Disease Associations	1.0	1.14166
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56684
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99647
CCR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00883688
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58282
PILRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00471535
Glucuronidation(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Unnamed_4_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Ketoprofen	CTD Gene-Chemical Interactions	1.0	null
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transferase activity, transferring glycosyl groups	GO Molecular Function Annotations 2015	1.0	null
Tyrosinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K10011427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48291
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34616
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)	Reactome Pathways 2014	1.0	null
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33404
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318272
hormone metabolic process	GO Biological Process Annotations 2015	1.0	null
LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K53192330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99588
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57371
Phase II - Conjugation of compounds	Reactome Pathways 2024	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7993
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.863
FOXA2	ENCODE Transcription Factor Targets	1.0	null
Elatoside I	HMDB Metabolites of Enzymes	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36686
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
2-Methoxy-estradiol-17beta 3-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Pluteus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	1.60931
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NI-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glutamyl-tRNA(Gln) amidotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61877
BRD-K04275703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08822
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64123
ls-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345928
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.3145
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.583
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.944113
Adenocarcinoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.315729
Alcohol use disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2322
SAMD9L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559029
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05626
glucuronosyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83764
Intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.858
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
BRD-K50066702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13419
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55312
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
beta-Estradiol	MW Enzyme Metabolite Associations	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9272
Bile secretion	KEGG Pathways 2026	1.0	null
BRD-K73562260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28528
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
response to hormone	GO Biological Process Annotations 2015	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.39338
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66064
BRD-K58138729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24267
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
CBX6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451898
BRD-K90429860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49808
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52738
BRD-K00938872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32101
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65416
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.30469
CTSZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68006
BRD-K79885457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32574
BRD-K91202220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99394
liver	HPA Tissue Protein Expression Profiles	1.0	0.965189
BRD-K38073091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0883
BRD-K22651517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32814
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
hsa-miR-1278	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0934
gp5d	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
Kernicterus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.748
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20265
BRD-K14702616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72207
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943461
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
cellular response to hormone stimulus	GO Biological Process Annotations 2015	1.0	null
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
Pregnanediol-3-glucuronide	HMDB Metabolites of Enzymes	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66445
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
Colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
Androsterone	HMDB Metabolites of Enzymes	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
Pigmentation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.465
Tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.197742
GATA3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54332480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21421
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
GSE196962_2_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28679
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48431
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol	HMDB Metabolites of Enzymes	1.0	null
BRD-K10923439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52147
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5MZ-01A-21R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7031-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9538
nucleotide-excision repair factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15672
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.110628
aromatic	GeneRIF Biological Term Annotations	1.0	null
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3a_DirectGene_CEBPA-Data3a_Genes_directly_regulated_by_CEBPA_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15282144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14497
BRD-A70099008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29755
kernicterus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.522659
16318415-TableS1	GeneSigDB Published Gene Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48941
BRD-K33272704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2662
Perturb_8155_KD_DDX59_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95427
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K31342827_GF 109203X_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16182
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09202
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087921
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309697
ACSL4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00849259
SGPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055897
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7114
monocarboxylic acid binding	GO Molecular Function Annotations 2015	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
15637295-Table3	GeneSigDB Published Gene Signatures	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.541
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03694
BRD-K34747076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39281
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430312
position	GeneRIF Biological Term Annotations	1.0	null
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57564
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.0
Intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.34
SKOV3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08342
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.60279
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5501
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315861
UACC893	DepMap CRISPR Gene Dependency	1.0	3.42003
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43562
RELA_01_30	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.90332
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R0-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all-trans-Retinoyl-beta-glucuronide	MW Enzyme Metabolite Associations	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
RAD51C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37826
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.335046
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
response to chemical	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.26
PCCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699859
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64509
Perturb_8219_KD_XRCC6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.91068
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
BMI-1_DEPLETION_GDS2445_115_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Ascorbate and aldarate metabolism	KEGG Pathways 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.012
Valproic acid glucuronide	HMDB Metabolites of Enzymes	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939604
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65083
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
THP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19067
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32628
CHUK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520976
identifies	GeneRIF Biological Term Annotations	1.0	null
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68454
BRD-K07798964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19079
ARID3A	ENCODE Transcription Factor Targets	1.0	null
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00403
BRD-K83312314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87403
Thrombophilia	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09805
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054835
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1764
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33099
Inflammation	CTD Gene-Disease Associations	1.0	1.70409
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308974
hsa-miR-101	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
CDC25C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611659
Bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.945
Betavulgaroside I	HMDB Metabolites of Enzymes	1.0	null
Juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14664
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438739
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1206
BRD-K45952474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38708
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
Clitoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
PEX11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57445
chr4_69533988_G_A_b38	GTEx eQTL 2025	1.0	1.13904
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
Glyciram	HMDB Metabolites of Enzymes	1.0	null
TWF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.003834
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99376
BRD-K85821470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05655
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09466
Viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.764
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03547
LN215	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13985
DARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556549
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00383232
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.39238
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
BRD-K22316029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56358
NCI/ADR-RES cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CSNK1G3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050813
BRD-K24377650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09812
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067713
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
BRD-K28216304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32354
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
SLC25A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488248
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
hsa-miR-4697-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC12368524-Supplementary_materials.pdf-21-REPIN1_REPIN1	Rummagene Transcription Factor Associations 2026	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
CRYZ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00412209
TUBG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554925
VDR-21846776-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60386
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2262
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66573
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K34977825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62404
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1214
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
Amelogenesis imperfecta type 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03641
TMUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76253
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23288
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58578
GTSF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509442
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.953
MLPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484285
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13566078_HY-10518_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
TNFRSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681335
glucuronidation	GeneRIF Biological Term Annotations	1.0	null
BRD-K33274327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46336
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43457
FGB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00850432
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05648
All-trans-retinoic acid	HMDB Metabolites of Enzymes	1.0	null
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954718
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043394
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55553
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
CEBPB	ENCODE Transcription Factor Targets	1.0	null
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
HL-7702 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.723352
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03964
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.71
Ehlers-Danlos syndrome spondylodysplastic type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
BRD-K74663731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34183
Dapagliflozin	DrugBank Drug Targets	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.823
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.466
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
CDK19_knockdown_148_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.18125
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056513
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91807
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941752
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.627672
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.248
BRD-K09160804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93411
RFLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8933
glucuronate metabolic process	GO Biological Process Annotations 2023	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851367
MIEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89397
ZNF496	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77624
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.71181
2-Methoxyestrone	MW Enzyme Metabolite Associations	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.916
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Cholesterol glucuronide	HMDB Metabolites of Enzymes	1.0	null
MLMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disulfiram_homo sapiens_gpl14550_gse42318	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62974
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07511
Esophageal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.961607
Perturb_10207_KD_USP15_SRP290188	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.01661
WT1_01_08	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.82133
Adenomatous Polyposis Coli	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K48880196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26871
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.194
1-Salicylate glucuronide	HMDB Metabolites of Enzymes	1.0	null
Perturb_9001_KD_KAT7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K71737889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13282
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.083868
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-LMS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
MAFF	ENCODE Transcription Factor Targets	1.0	null
distal tubular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23663
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23905877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75665
BRD-K53647853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17013
ASAH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00241246
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.76399
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.234
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25498
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.53928
Plant glandular hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
DMS153	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85233
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.273734
BRD-K21285405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01331
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15336
SEMA4G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00785091
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01058
enzyme	GeneRIF Biological Term Annotations	1.0	null
BRD-K52001024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18202
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4728-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09207
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.13091
Androsterone glucuronide	HMDB Metabolites of Enzymes	1.0	null
Ibuprofen	CTD Gene-Chemical Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PSAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574526
BRD-K37544873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14043
Flurbiprofen	HMDB Metabolites of Enzymes	1.0	null
15-Hydroxynorandrostene-3,17-dione glucuronide	HMDB Metabolites of Enzymes	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3903
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.571495
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.126332
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33166
XPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39745
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10367
NCIH716	CCLE Cell Line Gene Expression Profiles	1.0	1.37561
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04022
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.05274
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33166
BCPAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intrahepatic cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317909
specificity	GeneRIF Biological Term Annotations	1.0	null
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.786
IBUPROFEN, SODIUM SALT	DGIdb Drug Targets 2026	1.0	2.58205
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1835
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
ugt1a8	GeneRIF Biological Term Annotations	1.0	null
Esophageal Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.855
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09819
17-beta-estradiol 3-sulfate-17-(beta-D-glucuronide)	HMDB Metabolites of Enzymes	1.0	null
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.535
BRD-K21771449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96284
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12831