association	dataset	threshold value	standardized value
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962681
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17268
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AP3M1	Pathway Commons Protein-Protein Interactions	1.0	null
CPNE3	Pathway Commons Protein-Protein Interactions	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	4.22201
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.031377
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BCB000039-7536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hESC_Derived_CD184+_Endoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.34913
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3382
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.600992
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90625171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80686
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trichostatin A-4665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0964
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10453
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
osteosarcoma	GeneRIF Biological Term Annotations	1.0	null
BLOC1S2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K30655307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68424
TBC1D1	Pathway Commons Protein-Protein Interactions	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K58930048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02567
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1538
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNLRB1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01375
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837727
leukemogenesis	GeneRIF Biological Term Annotations	1.0	null
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45401
USF1	ENCODE Transcription Factor Targets	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
haloperidol-6163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PPM1B	Pathway Commons Protein-Protein Interactions	1.0	null
BCAP29	Pathway Commons Protein-Protein Interactions	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3884
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.930519
VPS11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85655
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890125
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5052
trichostatin A-1535	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11308
GATA2	ENCODE Transcription Factor Targets	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939788
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85478
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC22B	Pathway Commons Protein-Protein Interactions	1.0	null
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_JQ1_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.00921265
NRF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K10571700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54286
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48835953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0729
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831592
MCF7_UNC1999_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138746
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32454
minocycline-5496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
retinoic	GeneRIF Biological Term Annotations	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04396
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61147
Perturb_15127_KO_Mettl3_SRP363779	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE250534_2_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67352
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26868
COG4	Pathway Commons Protein-Protein Interactions	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57943
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38297
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3886
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00808
BRD-A22502911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69338
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01668
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.981096
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95369587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7381
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83114
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_13825_KO|OE_Nf1/Pten/Efgr_SRP302970	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.80419
allantoin-1678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K33453127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77709
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
guanfacine-1279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210604
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846833
BRD-K99462197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84235
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
SETDB1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51341
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06316
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961446
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.479
contributes	GeneRIF Biological Term Annotations	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59811
ECSIT	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80602847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06526
BRD-A52729710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81625
BRD-K82399478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01516
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256807
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846056
RS411	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58498
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45923
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950681
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61316
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36627
prochlorperazine-1640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NF2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02555
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
HEP-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50076
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.98011
hel	HPA Cell Line Gene Expression Profiles	-1.0	-1.1811
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50243
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37687
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5758
BRD-K17078647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66148
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Valproic acid sodium salt_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196272
BRD-K45520793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3583
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173003
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
GSE154940_1_v_0_nbdy_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1886
BRD-K12376164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2643
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12305
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Alendronate sodium trihydrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126022
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.452482
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3746
BRD-K32882942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.081
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABAC1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61608
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
lncap cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
xylazine-4066	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.234174
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24393
KIF2A	Pathway Commons Protein-Protein Interactions	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.720389
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_UNC0379_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123892
HDAC1	ENCODE Transcription Factor Targets	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27179
BRD-K45723655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16311
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAG1	Pathway Commons Protein-Protein Interactions	1.0	null
CDK5	Pathway Commons Protein-Protein Interactions	1.0	null
VTI1A	Pathway Commons Protein-Protein Interactions	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K30462643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42041
BRD-K30628727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23835
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25823
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28465
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.762397
BRD-K76174882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19877
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10272
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.83985
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79711
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18288
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906212
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875092
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K11269634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73114
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908204
BRD-K17940097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1464
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.785873
PML	ENCODE Transcription Factor Targets	1.0	null
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99561
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08456
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14632
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087199
A549_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0247352
Pharyngeal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25111
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-28 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1523
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82933
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026011
raloxifene-2738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30857
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33308
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97999
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.048
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2052	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38026
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49609
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.839173
BRD-K41305193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42394
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
CHMP2A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61274359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18712
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155142
Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06828
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93534327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71796
NFATC1	ENCODE Transcription Factor Targets	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21085
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8881
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1417
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39001
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19039785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31491
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22116
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959598
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24766
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-1.64207
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96794
COMMD3	Pathway Commons Protein-Protein Interactions	1.0	null
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13328
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849365
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
ZFPL1	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K70940767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32903
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23989
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_PHA-680632_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112745
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77679
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2681
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
examined	GeneRIF Biological Term Annotations	1.0	null
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14638
BRCA1	ENCODE Transcription Factor Targets	1.0	null
PLEKHA2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60364
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIK3C2B	Pathway Commons Protein-Protein Interactions	1.0	null
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28946
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11519602-41418_2024_1333_MOESM3_ESM.pdf-25-CCDC17_CCDC17	Rummagene Transcription Factor Associations 2026	1.0	null
acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.181222
BRD-K98455041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60307
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX14	Pathway Commons Protein-Protein Interactions	1.0	null
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252307
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865579
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5247_KO_Tfcp2l1_SRP288317	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
K562_Alisertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150452
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936708
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.966514
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29021
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61005
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08018
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63406
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21693
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.348284
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-29892750-EML-MOUSE-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.94618
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HE-18-HV99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205125
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34541722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0288
Nasopharyngeal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.84391
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
ULK3	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10948
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33054
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24243
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06947
BRD-K43316594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20315
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02477
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365006
MVB12A	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139923
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20014
GATA3-21867929-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269077
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73257
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20028052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03124
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69089961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51093
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54831
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27359
MYC-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70178
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE220520_5_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20303
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HS766T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828411
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38261
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12155
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52585
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20472
A549_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142768
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
treatment	GeneRIF Biological Term Annotations	1.0	null
CAL-54	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08972
LSG1	Pathway Commons Protein-Protein Interactions	1.0	null
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1595
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953565
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.22116
hsa-miR-2861	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05256
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79886
RALB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18558473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.64617
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91106
A549_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00914081
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5864
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4707-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68287
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50061
BRD-K20918933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10425
raubasine-6360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57527
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3857
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57337
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.166
TEAD4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Downregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.72408
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.64912
A549_JNJ-7706621_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166658
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.543756
BRD-K65860773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10095
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882328
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47564
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06712
MOSPD2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85823016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11492
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K25993054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19536
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.988663
F36P	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5647
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16121
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66764
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12706
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIK3R4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261866
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18686200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3085
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23462
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3892
MCF7_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00876615
NAGLU	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68918
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TA-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
JHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.68596
MCF7_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010369
RIF1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984835
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4126
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1C1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40199
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
VPS52	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3689b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12505
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65439
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90172
guanabenz-4642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IPCEF1	Pathway Commons Protein-Protein Interactions	1.0	null
MAPKAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55891520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06317
BRD-K47841020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18782
BRD-K64531971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15668
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0937
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.36742
PMC12648952-12915_2025_2452_MOESM4_ESM.xlsx-S4c-Pseudobulk_AP2_vs_B57-Unnamed_11_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0087234
BRD-K26866198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14736
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03345
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL72	DepMap CRISPR Gene Dependency	1.0	6.58314
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315532
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FNBP1L	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	4.48185
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.78881
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.97694
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61983
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.049951
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828308
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	1.3834
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00257
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.62375
JUND	ENCODE Transcription Factor Targets	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55715
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.10828
SELENBP1	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.73323
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33988
BRD-K70941721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08162
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38839
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81318113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07886
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1137
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4269	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968732
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21935
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17748_KO_Drd2_SRP238905	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.56644
CDC42SE2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5941
BRD-K46985581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14421
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890001
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66051
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889476
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48316
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
Gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.42
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0559
DTNBP1	Pathway Commons Protein-Protein Interactions	1.0	null
naloxone-4645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29383520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42315
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45384
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
EPB41L5	Pathway Commons Protein-Protein Interactions	1.0	null
COG5	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14436020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42141
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09265
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45567
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.058
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31699
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963265
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37994
BRD-K98595604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74794
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	GDSC Cell Line Gene Expression Profiles	-1.0	-2.25377
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912342
WASL	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Fedratinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167556
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97865
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220001
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56234278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30242
RAB35	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00045
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.45777
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88089
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.39925
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.929
JK1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81564
BRD-K25330450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56757
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-10-DNMT1_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4-PPBP	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32988
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64133
BRD-K20542687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00687
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.924747
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48295
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE214842_0_v_1_atf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LGR5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06431655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5798
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
partially	GeneRIF Biological Term Annotations	1.0	null
LAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.862904
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ionomycin-882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
isoniazid-1399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
knockdown	GeneRIF Biological Term Annotations	1.0	null
ketotifen-1583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833661
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16670438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18323
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35948
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04375
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455701
BRD-K36725646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00732
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCP1	CCLE Cell Line Gene CNV Profiles	1.0	1.94196
BRD-K90762344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25084
BRD-K94058780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47785
trichostatin A-5981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adult Hepatocellular Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354828
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.33298
SW1417	GDSC Cell Line Gene Expression Profiles	1.0	2.01014
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03384
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	0.878483
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.849264
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mat-Ly-Lu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
JHOM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35075
alpha	GeneRIF Biological Term Annotations	1.0	null
K562_UNC0379_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202361
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18618
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50632
BRD-K17910820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64006
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20258
GSE207301,GSE207303_0_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
CHEK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.49184
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55916310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39445
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3727
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953046
LEMD3	Pathway Commons Protein-Protein Interactions	1.0	null
STK38	Pathway Commons Protein-Protein Interactions	1.0	null
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13515483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05042
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03616
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27093
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16489042-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
vinburnine-1788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02803
SiHa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
CBC631 (AKAP13)	NURSA Protein Complexes	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92646
FERMT1	Pathway Commons Protein-Protein Interactions	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81476
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87472
ARL15	Pathway Commons Protein-Protein Interactions	1.0	null
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13526
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1365
BRD-K26435104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0108
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824269
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARL6IP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12844
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K32043305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54064
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.72982
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97952
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05844
BRD-K91399333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40144
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64389
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07417
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
carcinine-4809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14923
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29619
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
loperamide-1949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978051
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.5539
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79379
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fulvestrant-2698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45892
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90553
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32448
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.977171
BRD-K70584304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67582
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23249
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K98880643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97787
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39039
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
STX12	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33994
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98264372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82863
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VPS37B	Pathway Commons Protein-Protein Interactions	1.0	null
PLEK2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11156_KO_Tsc1/p62_SRP069010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.28577
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65065
chlorpromazine-419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96427
imidurea-5481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8989
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64262
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.63534
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
RANBP17	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K35108166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04702
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hFOB 1.19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89179622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28913
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
CIB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949009
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11813
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1552
rolitetracycline-5331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2B1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16038
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-14-GN61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309506
BRD-K45503385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22313
higher	GeneRIF Biological Term Annotations	1.0	null
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24565
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48043
BRD-K68270916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45158
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16997
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
A549_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132703
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41567
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58908
ARFGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GADD45GIP1	Pathway Commons Protein-Protein Interactions	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20683
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51424
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18922
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMEK1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916823
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85472
BRD-K04704273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16793
VPS26A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29764
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0651
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9797_OE_YAP1_SRP132362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09546
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CCDC50	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150784
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31015
BRD-A42612443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37257
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956273
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47633
A549_ENMD-2076_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167437
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RMND1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09266
multistep	GeneRIF Biological Term Annotations	1.0	null
drofenine-3455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gastric epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536625
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44253
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5125-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	3.75222
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.10109
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46302
roles	GeneRIF Biological Term Annotations	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28191
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Crizotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013351
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63161
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17299
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38839
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1759
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65449
microrna	GeneRIF Biological Term Annotations	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64978
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5308
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952302
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06274
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645725
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840803
KIFC1	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
daunorubicin-4983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4887-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84577
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Very large inducible GTPASE (VLIG)-type guanine nucleotide-binding (G) domain	InterPro Predicted Protein Domain Annotations	1.0	null
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14773
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04193
CHD7	ENCODE Transcription Factor Targets	1.0	null
BRD-K21327356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00984
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827323
SP1	ENCODE Transcription Factor Targets	1.0	null
trichostatin A-4632	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
RHOA	Pathway Commons Protein-Protein Interactions	1.0	null
VPS18	Pathway Commons Protein-Protein Interactions	1.0	null
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9893
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895505
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77547
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
JAK1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51204
SNAP23	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04613
MCF7_Valproic acid sodium salt_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132005
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04891
MYC-18940864-HL60-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09307
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11079
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02064
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07012
trichostatin A-3462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
BRD-K29111485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03039
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.27854
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09147
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04339
A549_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131667
MAN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57719
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17833
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09027
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38273742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06713
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12064774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17032
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935214
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	3.81798
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.848574
icSARS CoV_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.487679
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88625883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46013
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30206
BRD-K30264389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44736
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL6413 (BCOR)	NURSA Protein Complexes	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12208
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07665396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11047
anion binding	GO Molecular Function Annotations 2015	1.0	null
RABEP1	Pathway Commons Protein-Protein Interactions	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CISD2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21779
BRD-K46609723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3568
BRD-K37558338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03274
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53133
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889756
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	4.30936
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
SEL1L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04426746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43284
PMC9314667-Table_1.xlsx-Regulons-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.972149
GM2A	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D15	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-dORF6_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65495
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42457027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28568
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28519
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CACYBP	Pathway Commons Protein-Protein Interactions	1.0	null
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42964587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48073
chloroquine-7251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39055
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36808
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323841
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66526
MCF7_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163883
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatocarcinogenesis	DisGeNET Gene-Disease Associations	1.0	null
phenanthridinone-1115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23834
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08707
15831697-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34258
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26615
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
MAPK8IP3	Pathway Commons Protein-Protein Interactions	1.0	null
SHD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22876
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1026
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.439
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29339
BRD-K93990956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02311
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48912
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55072
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94597
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5213
CHP1	Pathway Commons Protein-Protein Interactions	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67270926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62567
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25436
BRD-K44224150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46275
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.999549
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62718031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25858
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26844
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29508
SNTB2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3155
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.02896
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bergenin-7224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
K562_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163177
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59015
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79986
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46401
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44772
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07417
STK39	Pathway Commons Protein-Protein Interactions	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
ZNF723	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55487
HOOK1	Pathway Commons Protein-Protein Interactions	1.0	null
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.615169
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08239
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Recurrent Tumor	DisGeNET Gene-Phenotype Associations	1.0	null
HAUS3	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trifluoperazine-2389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTDNEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82253
PSS008	DepMap CRISPR Gene Dependency	1.0	2.27069
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MEG-01	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63236
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39683
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GALC	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11352
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5026
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07033
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00461
Multiple Tumors	DisGeNET Gene-Phenotype Associations	1.0	null
ursolic acid-7181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB6A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K20072174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71462
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4507	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Prestwick-972-7266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SC-596 (CCNA2)	NURSA Protein Complexes	1.0	null
BLOC1S4	Pathway Commons Protein-Protein Interactions	1.0	null
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849772
MCF7_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221929
CLCN7	Pathway Commons Protein-Protein Interactions	1.0	null
PACSIN2	Pathway Commons Protein-Protein Interactions	1.0	null
TSC1	Pathway Commons Protein-Protein Interactions	1.0	null
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293028
MCF7_Rucaparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015731
CAB39	Pathway Commons Protein-Protein Interactions	1.0	null
Osteosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
RASL11A	Pathway Commons Protein-Protein Interactions	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K79me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74975
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
BRD-K97470305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32437
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99599
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12828
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53402320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03821
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDGFRA_activemutant_54_GSE17743	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.87831
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12505
TELO2	Pathway Commons Protein-Protein Interactions	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884595
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17139
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05568
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
EPS8L2	Pathway Commons Protein-Protein Interactions	1.0	null
IC-86621-7518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956634
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163023
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49409924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3505
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894519
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72042
EIF2B4	Pathway Commons Protein-Protein Interactions	1.0	null
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PLA2G4B	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-1637	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52773
CENPV	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06475437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4674
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.087
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40258
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41184
NCIH1693_LUNG	CCLE Cell Line Proteomics	1.0	2.79317
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05742
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.09934
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21537
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20763
BRD-K13803936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.119
MEF2A	ChEA Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79305
Lung squamous cell carcinoma_LUSC_TCGA-58-A46N-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27967
TCF3	ChEA Transcription Factor Targets	1.0	null
BRD-K18657361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12543
BRD-K65737790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66456
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
FRMPD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0613
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917377
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12377
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55009
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13731
natural	GeneRIF Biological Term Annotations	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
LRP10	Pathway Commons Protein-Protein Interactions	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.089
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
naproxen-6358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856223
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
EGR1	ChEA Transcription Factor Targets	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19103
hsa-miR-3151	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLOT1	Pathway Commons Protein-Protein Interactions	1.0	null
ATG5	Pathway Commons Protein-Protein Interactions	1.0	null
GPR143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60863
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K45134469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56847
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.43852
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01954
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943486
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01884
UHRF1	Pathway Commons Protein-Protein Interactions	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1505
BRD-K32595757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48292
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.956614
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5604
K562_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161645
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47999
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64573
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82682
PMC8914074-Table1.XLSX-S8-Alternative_splicing_events_from_corneal_epithelial_samples_and_peripheral_blood_samples_of_KTCN_patients_VSX1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66375
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K95591068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51564
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040733
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9895410-Table_1.xlsx-Neuroendocrine_regulation_genes-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24688
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.948881
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CaSki cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50201262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67498
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1965
CLASP2	Pathway Commons Protein-Protein Interactions	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.094815
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33341
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18771
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.267644
BRD-K06886551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16385
hsa-miR-3689e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.77458
cyclizine-1731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.29688
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45959036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15695
AP1M2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10704442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70254
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-10a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35201
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNAP29	Pathway Commons Protein-Protein Interactions	1.0	null
THAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01968
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832473
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29416
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00997
RINT1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154478
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_DN_AA_DN-AA_DN_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23431
hsa-miR-4680-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
A549_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114898
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39001
mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223347
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21278
FGD4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76499
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85025
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
BRD-K49755501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08302
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Eosinophilic esophagitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3034
BRD-K33697018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2465
tetramisole-2489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06973
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
BRD-K86988191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07399
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26868
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91876
dbtrg05mg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132827
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34901
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38839
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.28797
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01341
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32898
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846833
KIF4A	Pathway Commons Protein-Protein Interactions	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
BRD-K05799189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23689
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.845477
uterine cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K02882086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22615
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38365
MYOG	ENCODE Transcription Factor Targets	1.0	null
metformin-2	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7974
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05663
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
SFT2D2	Pathway Commons Protein-Protein Interactions	1.0	null
JP-4-043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01454
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922638
BRD-K81821040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01121
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33433
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.25022
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24905
BRD-K11667893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76786
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.957348
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAZ1A	Pathway Commons Protein-Protein Interactions	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5833
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850491
Eiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6XC-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBE	DepMap CRISPR Gene Dependency	1.0	2.02491
QF-55-QV81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291051
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00037
carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28845
COG3	Pathway Commons Protein-Protein Interactions	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1104
ERGIC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
RAB19	Pathway Commons Protein-Protein Interactions	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.953477
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11936
HOP62	BioGPS Cell Line Gene Expression Profiles	1.0	1.79557
BRD-K54042694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0538
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53492
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24719325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28439
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33438
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71818
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.02294
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9262
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.830706
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5203
HeLa-229 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831132
SCP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80317
CDK11A	Pathway Commons Protein-Protein Interactions	1.0	null
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31803
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09825
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18604
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5244
prazosin-942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
trichostatin A-6493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9171
BRD-K99522349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87496
SWAP70	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL8A	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WASH2P	Pathway Commons Protein-Protein Interactions	1.0	null
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03921
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166284
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.07286
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1278
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.78713
epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57027644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51654
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1065
K562_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235066
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.87117
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29189
SNX15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41306
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.457176
SNX7	Pathway Commons Protein-Protein Interactions	1.0	null
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13337
MCF7_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242686
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CP-690334-01-4561	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50593
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17574409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08937
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48581
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45971
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.151
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07114
NRAS	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24357
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33085
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207975
LB996-RCC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06701
SCARB2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41999717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2717
STX18	Pathway Commons Protein-Protein Interactions	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35633
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903113
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312957
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60132
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346698
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01457
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76966915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0671
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47297
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K95875837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49379
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03921
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.99949
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0504
me180	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
TAOK3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
OV-17R	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03351
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A633-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14112
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.773589
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825606
CNN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50216418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30465
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9452
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
KMRC1_KIDNEY	CCLE Cell Line Proteomics	1.0	3.49169
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hepg2	GeneRIF Biological Term Annotations	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51897928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23559
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0118
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20513
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_10874_OE_LIPA_SRP328944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.39752
EBF1	ENCODE Transcription Factor Targets	1.0	null
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33801
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933044
DGKK	Pathway Commons Protein-Protein Interactions	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122371
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65932
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43875
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71676
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13423
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08239
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SH3GLB1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
clomifene-6648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338379
AKT1_knockdown_123_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72523
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73732
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830771
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.157
Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2326
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77787814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99495
BRD-K71842353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.90123
BRD-K78886448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35043
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26998
marker	GeneRIF Biological Term Annotations	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040583
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862113
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3-22036565-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33936
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865936
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K59041191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35293
ANXA5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948021
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25708
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO678_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	10.5592
meteneprost-7552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10702
EIF2D	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-6340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66154
PLEKHH1	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
Medullary thyroid carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
ACSF2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39198
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.65861
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59432
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.1388
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
BRD-K76921877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9282
K562_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165478
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARFRP1	Pathway Commons Protein-Protein Interactions	1.0	null
oxaliplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41128
ATP6V0C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75207324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03846
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222571
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.16755
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29176
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13783
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943471
TMED1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36756
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A79884839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03571
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23464
BRD-K87666020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57683
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01502
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845765
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32787834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28842
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL-12T	GDSC Cell Line Gene Expression Profiles	1.0	1.88803
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70494
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66615
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27784
BRD-K22384464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33757
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74437
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
sh-sy5y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00545
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuroblastoma	GeneRIF Biological Term Annotations	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873346
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01054
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43874
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8510-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20348534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39654
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
HIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853987
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_BMS-265246_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161036
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45012
KLE	DepMap CRISPR Gene Dependency	1.0	3.29547
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
clebopride-1292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906797
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-339-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EXPH5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.44155
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60234
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01544
MEF2A-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981223
BCB000040-7554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ITK_knockout_242_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81081
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8507_KO_Gata4_SRP277626	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.92839
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72563
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905427
CPNE1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37526
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB18	Pathway Commons Protein-Protein Interactions	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08455
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03997
HN	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
nicardipine-6297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTP binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75224
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.978247
LMO7	Pathway Commons Protein-Protein Interactions	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228959
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.9799
hsa-miR-3940-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82441
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22781
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1007
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
PSAP	Pathway Commons Protein-Protein Interactions	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	0.858544
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
OPM2	DepMap CRISPR Gene Dependency	1.0	2.4505
BRD-K92462786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84547
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78904317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79048
sk-n-sh cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214954
BRD-K59030325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91383
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848313
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	2.01647
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08446
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8427
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844482
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43106
Nasopharyngeal carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91181
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
STX3	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JO-01B-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.395
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-6951	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TM9SF1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163443
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.436956
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50081142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31561
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.84467
Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A61P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDFY1	Pathway Commons Protein-Protein Interactions	1.0	null
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18732
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02316
BRD-K95294904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4571
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984486
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02502
PPP1R9B	Pathway Commons Protein-Protein Interactions	1.0	null
NF2	MSigDB Cancer Gene Co-expression Modules	1.0	null
TBC1D17	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37276417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19343
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5619
BRD-K05123945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53004
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
APPL2	Pathway Commons Protein-Protein Interactions	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32305
genistein-1176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40129
BRD-K69175109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51842
BRD-K86263698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90943
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02261
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SC-58125-208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trichostatin A-3993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.181
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75599
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916532
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867395
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95615652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.89279
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842456
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47786
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98249237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27817
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGAP8	Pathway Commons Protein-Protein Interactions	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65294
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urg4	GeneRIF Biological Term Annotations	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K90882192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14769
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31795
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951474
BRD-K85525164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3854
TSG101	Pathway Commons Protein-Protein Interactions	1.0	null
GDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38763
ILK	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K97485956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06416
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236659
trichostatin A-7324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
urgcpurg4overexpression	GeneRIF Biological Term Annotations	1.0	null
SNPH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61934
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64934
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2812
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
LSM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32278
BRD-K28565184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44662
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015317
ARL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856905
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82827604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23929
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828814
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFEB	ChEA Transcription Factor Targets	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16972
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18138
H3K4me1_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K84586608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32532
PTPN6	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulindac-1815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0907
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08972
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.880271
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76157
AGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
presence	GeneRIF Biological Term Annotations	1.0	null
ASAH1	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158394
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12927
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.65324
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03226
PTK2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01762107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50795
A549_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133518
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911954
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72372
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06812
hesperetin-1947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40505
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hacat	HPA Cell Line Gene Expression Profiles	1.0	0.966942
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRTP1	Pathway Commons Protein-Protein Interactions	1.0	null
CAPN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5531
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07807
thiocolchicoside-1726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GIGYF2	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878642
NR2F2	ENCODE Transcription Factor Targets	1.0	null
BRD-K67734449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17405
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13829
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11246
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32622
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
143B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45441
RRAS	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR4_OVARY	CCLE Cell Line Proteomics	1.0	2.61192
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07608
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	2.4698
U178	CCLE Cell Line Gene Expression Profiles	1.0	2.47231
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01658
D283MED	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78985
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18115
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96885
BRD-K83270526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46868
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHMP5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903545
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHMP1A	Pathway Commons Protein-Protein Interactions	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3789
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57005
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1391
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.466
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18312
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56567
ARHGAP35	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10206_KO_SLC35F2_ERP006028	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46712
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02047
BRD-K95653016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77714
BRD-K77011363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01112
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10798
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mania	GWASdb SNP-Phenotype Associations	1.0	0.436956
RHOG	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K62707745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3136
BET1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21393
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	0.966136
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222568
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31385
BRD-K58715359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63845
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-1400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39716
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06609
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28336
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sirt1_OE_GDS2658_140_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22992
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32723
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.88444
suggests	GeneRIF Biological Term Annotations	1.0	null
BRD-K23956364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99903
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860008
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BRD-K38980456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11714
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5707
BRD-K23533429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52396
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10668
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11518
Simotinib_SW48	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00677351
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
BRD-K30917841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17072
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59952
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VPS39	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
pparalpha	GeneRIF Biological Term Annotations	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS28	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902211
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47314501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43857
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12986
BRD-K51320582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16375
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75599
BRD-K62612761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03649
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19710723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43334
POU5F1	ChEA Transcription Factor Targets	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65477
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27508
FLII	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95213130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36882
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29514
MCF7_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154271
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960515
ADAM10	Pathway Commons Protein-Protein Interactions	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414673
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.2352
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08155
BRD-K79329532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56341
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998861
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02049
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MU-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25251
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3617
MTOR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0294
trichostatin A-331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_7056_KO_Ogg1_ERP107154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33406
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A907-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.983057
GSE184133,GSE184137_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0061
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04095
ARL8B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STX4	Pathway Commons Protein-Protein Interactions	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02676
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00932
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16397
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12096
SNU-398	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30513
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21639
Nucleus of the solitary tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06812
hsa-miR-1343	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
PCTP	Pathway Commons Protein-Protein Interactions	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307855
Peak insulin response	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.36886
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41245
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
increases	GeneRIF Biological Term Annotations	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8405_SRFBP1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.17076
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01424
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80445
trichostatin A-1471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
valproic acid-345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
NF1	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGEF26	Pathway Commons Protein-Protein Interactions	1.0	null
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105584
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856267
BRD-K08799663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81437
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05617
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
ABHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17397
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHA1	Pathway Commons Protein-Protein Interactions	1.0	null
CMK115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49278
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0626
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19381
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
BRD-K28391526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65664
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68056
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178025
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850582
RTN3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
uterine endometrium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2587
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.63094
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7444_RPL19_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.12587
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08608
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4247
benzydamine-1552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14483
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05000526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05811
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2165
Brain Lower Grade Glioma_LGG_TCGA-CS-5393-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2876
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07032
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98355
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54839019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12335
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52586
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950366
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871528
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
17880687-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K63809385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39856
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.78297
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20744
BRD-K24039194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06832
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13109
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5121
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16212
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93787
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892009
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.947118
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04346
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18057
SCAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31747470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37643
BRD-K83185986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60956
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99051
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2578
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26188
trichostatin A-5086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5604
albendazole-7164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16319
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824156
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-1672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88224221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14226
biological_process	GO Biological Process Annotations 2015	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18274
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19462
clindamycin-7172	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARAP3	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120344
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996158
BRD-K93017276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97545
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03714
BRD-K82284644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97992
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59914
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55672
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.070711
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB10	Pathway Commons Protein-Protein Interactions	1.0	null
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1G1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12985
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882735
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
topiramate-915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K85059356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.50308
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055032
BRD-K44696459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82701
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06007
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.5822
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29339
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.181798
BRD-K36847650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5247
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KNS42	DepMap CRISPR Gene Dependency	1.0	2.24348
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.879415
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872959
ChIP_MYC_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861108
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04393
COLO-680N	GDSC Cell Line Gene Expression Profiles	1.0	1.4981
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14014
BRD-K77706833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41096
GBA	Pathway Commons Protein-Protein Interactions	1.0	null
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14405
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.268
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282288
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29691
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
LP-533401	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62912
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3GL2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K72125659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64263
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49006
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61284
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1536
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51085
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.834618
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989421
ARHGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
NPC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34232791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28577
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999757
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.85706
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.5539
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BLOC1S1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34097
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hecogenin-7175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25999
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49847771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22285
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEC50B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88409
SH2D3A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K39858575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48643
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21256
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15855
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43013
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52238
BRD-K09473191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33632
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04275
RAB25	Pathway Commons Protein-Protein Interactions	1.0	null
Cervix Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C-33A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
MCF7_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141629
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2702
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68769
BRD-K38858314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44469
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856936
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.212
BRD-K22185032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05572
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21074
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24523
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.847072
BRD-K66039243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36671
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867003
BRD-K83294522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53518
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RSF1	Pathway Commons Protein-Protein Interactions	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293965
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.33019
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902834
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endocytosis complex	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30239
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16727544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0723
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.571
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39489370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47329
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VN-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929946
BRD-K12801140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0407
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83897
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04409515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69546
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.875794
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.739557
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671911
RCOR1	ENCODE Transcription Factor Targets	1.0	null
RABL2A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.99581
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095268
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86937728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53463
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01029
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938929
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54224946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35837
hsa-miR-4487	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
MCF7_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139825
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNB1	Pathway Commons Protein-Protein Interactions	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286241
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0675
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24673
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98828
EIF2B2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92222
BRD-K43205312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26383
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03507
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80467627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47047
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05298
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83404
Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL10RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580253
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067765
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.08078
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29727
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7192
BRD-K44760023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57573
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE241701_4_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03777
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07212
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22955
SAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81529
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865108
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222699
BRD-K02061146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85061
SNX8	Pathway Commons Protein-Protein Interactions	1.0	null
useful	GeneRIF Biological Term Annotations	1.0	null
PPP5C	Pathway Commons Protein-Protein Interactions	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943088
VMRC-RCZ	GDSC Cell Line Gene Expression Profiles	1.0	1.46549
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1023
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02995
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PICK1	Pathway Commons Protein-Protein Interactions	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48507
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1669
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
fipexide-3176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nitrofurantoin-2341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952325
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52276
BRD-K68401280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92223
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5426
Lung squamous cell carcinoma_LUSC_TCGA-79-5596-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38741
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916741
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4431
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10645
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52086
BRD-K98427581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0938
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45277
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.27282
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23124
BRD-K47536398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53969
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00139
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43885
Perturb_11839_KO_Slc7a13_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72549
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.988551
MON2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76997656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22395
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39001
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73454
GTEX-NPJ8-2426-SM-3MJHL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825403
ATF2	ENCODE Transcription Factor Targets	1.0	null
PLEKHF2	Pathway Commons Protein-Protein Interactions	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19198
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mepyramine-7223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56585
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDNL2	Pathway Commons Protein-Protein Interactions	1.0	null
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
RAB3GAP1	Pathway Commons Protein-Protein Interactions	1.0	null
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409731
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63881
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223604
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16562
BRD-K54007898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07385
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27372445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14783
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KASUMI2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69152
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06885
GLYR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03986
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57512
BRD-K48407262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68531
BRD-K65597286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58839
HIP1R	Pathway Commons Protein-Protein Interactions	1.0	null
cyclin	GeneRIF Biological Term Annotations	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.559062
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924615
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.78501
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.267977
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1C2	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85782
BRD-K44828787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23581
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CNPY3	Pathway Commons Protein-Protein Interactions	1.0	null
PRKAR2A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989116
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6837
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85500722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45066
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34832
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA3	Pathway Commons Protein-Protein Interactions	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26952
3-hydroxy-DL-kynurenine-1109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914032
ANXA11	Pathway Commons Protein-Protein Interactions	1.0	null
KLF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5715
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00931
BRD-K34700473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3706
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33495
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214129
BRD-K87654551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30502
tamoxifen-1366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82315
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05301
CREB1	ENCODE Transcription Factor Targets	1.0	null
VPS4A	Pathway Commons Protein-Protein Interactions	1.0	null
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28447
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4269
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80084
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82435
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
ASPSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70978931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40252
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982112
BRD-K54837058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16342
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841685
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
MAPK13	Pathway Commons Protein-Protein Interactions	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F6_NR2F6	Rummagene Transcription Factor Associations 2026	1.0	null
ACOT11	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54398
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967887
BRD-K64840743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20292
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AP3S1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K91575768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64803
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909369
HDAC6	ENCODE Transcription Factor Targets	1.0	null
H4	CCLE Cell Line Gene CNV Profiles	1.0	2.15631
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OV-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
trichostatin A-5822	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936087
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08652
COLO792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46424
K562_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165165
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19088
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46195
VAC14	Pathway Commons Protein-Protein Interactions	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
MYO6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
HuH-7	GDSC Cell Line Gene Expression Profiles	-1.0	-2.65214
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.467042
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37738
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24772
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044363
BCCIP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851461
CDC23	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173101
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24671
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.882
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6085
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43703
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37192
BRD-K55867695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43354
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06708
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6045
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89923892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55381
CSNK1A1	Pathway Commons Protein-Protein Interactions	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56685
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05392698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23269
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.4524
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19827
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
related	GeneRIF Biological Term Annotations	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTSA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11931
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025435
ANAPC7	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33215
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17201
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22455
VPS25	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02172
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.851931
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07748
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04584
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00377
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50849
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884022
BRD-K95788660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71061
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WB-4101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01679
MAPKAPK2	Pathway Commons Protein-Protein Interactions	1.0	null
SNX3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55244
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A69196860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46308
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69378
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36755
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93745
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
profiles	GeneRIF Biological Term Annotations	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38604123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46992
BRD-K70158474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65642
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17638
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104811
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36069
MCF7	DepMap CRISPR Gene Dependency	1.0	2.94947
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50841
PMC8586238-41467_2021_26788_MOESM6_ESM.xlsx-S2A_CDE_genes-S2A_CDE_-_genes_of_the_two_CCD_genes_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63225
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27969
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6308
K562_YM155_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165835
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
NB5	GDSC Cell Line Gene Expression Profiles	-1.0	-2.04817
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43332
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71145
Bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
CLPB	Pathway Commons Protein-Protein Interactions	1.0	null
LYN	Pathway Commons Protein-Protein Interactions	1.0	null
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56332068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0434
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3991
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07396820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8718
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68433511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44391
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014563
BRD-K52319351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05123
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56901
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07717
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21619
RAB23	Pathway Commons Protein-Protein Interactions	1.0	null
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14816
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02561
NCIH2122	DepMap CRISPR Gene Dependency	1.0	2.06798
closely	GeneRIF Biological Term Annotations	1.0	null
USP9X	Pathway Commons Protein-Protein Interactions	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.78881
ACAP2	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01014
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87533
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6474-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171129
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981828
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13438
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43335
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.461252
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K84310612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84814
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38549
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX6	Pathway Commons Protein-Protein Interactions	1.0	null
Gastric adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92006
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83976
medial parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93807
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29421
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K32879108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35582
BRD-K86102179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97028
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7372
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
RAPGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31493
EPS8L3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8354-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lisuride-1962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hepatitis b	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.409414
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14435
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17765399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10397
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11758
Liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26881
BRD-K19702946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17374
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nicergoline-6251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200402
BRD-K65445351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44584
RUNX3	ENCODE Transcription Factor Targets	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGEF10L	Pathway Commons Protein-Protein Interactions	1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229233
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31989
GSE102187_0_v_1_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7416
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.30873
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23188
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.530446
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5929
TEAD4	ChEA Transcription Factor Targets	1.0	null
GATA2-21666600-HMVEC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulators	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29392
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10668
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
haloperidol-1955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
icSARS CoV_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00356
Perturb_13826_OE_Pdgfra_SRP302970	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44193
GTPBP1	Pathway Commons Protein-Protein Interactions	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1559
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04745
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RALA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE126463_4_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10529
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.743464
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33833
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.890572
BRD-K50924315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06257
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060284
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ARL2	Pathway Commons Protein-Protein Interactions	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144917
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K92565319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02475
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03702
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
triprolidine-7008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02279
MYC	ChEA Transcription Factor Targets	1.0	null
MCF7_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138854
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7253-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.41564
betazole-6344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41831
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02022
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26545
BRD-K72721410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40064
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8329
BNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07574
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02339
hsa-miR-200a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22967
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38095
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2523
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
predicting	GeneRIF Biological Term Annotations	1.0	null
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
NMC-G1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34621
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04035
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33054
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408559
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52304
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8098
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38446773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11286
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.567267
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175245
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PTP4A1	Pathway Commons Protein-Protein Interactions	1.0	null
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11176
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23039
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.08341
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44527
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STAMBPL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83204
CRCGN016_MCF10A.TP53.M_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3312
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15806
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880029
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
SOX2	ChEA Transcription Factor Targets	1.0	null
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02049
PLEKHG3	Pathway Commons Protein-Protein Interactions	1.0	null
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
Protein quality control and ubiquitin-proteasome system regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
lincomycin-7411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UNC93B1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13610_KD_Srsf11_SRP136943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.22118
BRD-K72317601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20366
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828218
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hepatocarcinogenesis	GeneRIF Biological Term Annotations	1.0	null
GOLPH3L	Pathway Commons Protein-Protein Interactions	1.0	null
NUP50	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K30674442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88106
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49927
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9094
DUSP3	Pathway Commons Protein-Protein Interactions	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99375
E2F4	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883491
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-dORF6_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.10584
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16091
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832293
NCOA2_KO_GDS4785_172_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01855
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ANXA9	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9911
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.939964
UACC893	CCLE Cell Line Gene Expression Profiles	1.0	1.51886
ERGIC2	Pathway Commons Protein-Protein Interactions	1.0	null
ITPK1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826273
BRD-K16705434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07931
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16609
CRCGN016_MCF10A.WT.HP_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03583
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151435
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VAPA	Pathway Commons Protein-Protein Interactions	1.0	null
Choroid plexus carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991116
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_14660_KO_Insm1|Neurod1_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.2309
hbxag	GeneRIF Biological Term Annotations	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.590712
TRAPPC5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K69355244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22614
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7681
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UCHL3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K43729445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39839
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04243
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89017
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64337
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1024
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877032
ASPC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.819505
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413151
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07481
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955156
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89407
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053005
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
guanabenz-1961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.24162
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18768055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58959
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3603
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endocytic regulation via ubiquitination 1	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2616
HC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OSBPL3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K28512751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40208
IMR32	DepMap CRISPR Gene Dependency	1.0	2.61369
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890848
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
TE-11	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76957
benzydamine-7169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
N6-methyladenosine-1271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HN	CCLE Cell Line Gene CNV Profiles	1.0	2.5423
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.58478
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72359
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05509
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.037
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83801418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47876
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2304
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20157822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.191
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEC	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARF6	Pathway Commons Protein-Protein Interactions	1.0	null
DANG	DepMap CRISPR Gene Dependency	1.0	3.86392
TLN2	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88924787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42776
BIN1	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70021
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16369
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04036
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06492501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00083
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06275
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34354
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075313
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02848
MCF7_Cediranib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130826
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916496
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15477
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7002
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydralazine-2349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38737
MXI1	ENCODE Transcription Factor Targets	1.0	null
HSC-T6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
A549_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191853
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877092
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K92910000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50978
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4715
No annotation - 1	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K34009761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58832
GBF1	Pathway Commons Protein-Protein Interactions	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68845
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50522
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.30347
ivermectin-1367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trichostatin A-1732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11288
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AIDA	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-7105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58756877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13449
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84133
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LN382	CCLE Cell Line Gene Expression Profiles	1.0	2.06371
GOLT1B	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEDD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FIG4	Pathway Commons Protein-Protein Interactions	1.0	null
A549_2-Methoxyestradiol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141499
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43828
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.61042
TAF1	ENCODE Transcription Factor Targets	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.06456
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16587
BRD-K48113109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57998
hsa-miR-1238	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3095
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28055
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26219
hsa-miR-484	MiRTarBase microRNA Targets	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
BRD-K99446825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82174
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAN	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4730-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076682
GOLPH3	Pathway Commons Protein-Protein Interactions	1.0	null
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12713
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39009
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	1.69394
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92364
HMGN3	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K46639367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75929
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.734622
loxapine-2016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2659-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07526417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0185
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982236
hsa-miR-3689a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K08927194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60974
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-141	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
A549_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014353
BRD-K68853384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26134
NKIRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
AP1S1	Pathway Commons Protein-Protein Interactions	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681146
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38578
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31887
BRD-K86237035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35462
VAV2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42653
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01133
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963285
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845222
LN428	CCLE Cell Line Gene Expression Profiles	1.0	2.13236
Pharyngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
trichostatin A-5950	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28345
TET1	ChEA Transcription Factor Targets	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850491
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21549
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848176
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-6454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
USE1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.15083
RAB33B	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1R7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930333
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40095
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K11566982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58299
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00245
BRD-K56214240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28253
SH-SY5Y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
TJP2	Pathway Commons Protein-Protein Interactions	1.0	null
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SEC31A	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Selisistat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162608
BRD-K28399883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67284
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02612
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83488
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28927
CSNK1D	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
du145	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMO	MSigDB Cancer Gene Co-expression Modules	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Choroid plexus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
PHLDA2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K18801549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02832
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41639
BRD-K85722065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56303
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.81986
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4657
BRD-K85851814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90453
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8024
HAX1	Pathway Commons Protein-Protein Interactions	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14866
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38639
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.16528
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.314
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLN5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42535
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35175
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939466
BRD-K98271666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12852
EZH2	ENCODE Transcription Factor Targets	1.0	null
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STARD10	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09058
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIC8A	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228036
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malignant Tumor Of Cervix	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0811
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66525
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90718
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41191
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11175
RAB43	Pathway Commons Protein-Protein Interactions	1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02113
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15274
BRD-K82244940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35503
BRD-K75738997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1522
RAB11B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K00590556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75147
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22907
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404189
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25833
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.151743
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35517098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40461
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10547
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09148
BRD-K00423214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36255
NEK6	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.86344
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09874
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54018
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42245
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23938
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986088
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09874
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497487
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40582
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.07561
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFAIP8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K21312826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28566
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STEAP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K83115645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0913
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901768
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13126
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864665
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3162-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60745
RAB1B	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1112
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16954129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2909
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05484
NRF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hMPV_6Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31572
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53002
STXBP3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
EPS8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78438852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33949
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10265
BRD-K67014046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16952
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03889
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.10758
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980769
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32117
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.841442
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12469
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849314
USP6	MSigDB Cancer Gene Co-expression Modules	1.0	null
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13299
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96651
MCF7_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154941
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34238
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DCTN3	Pathway Commons Protein-Protein Interactions	1.0	null
GAPVD1	Pathway Commons Protein-Protein Interactions	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
Uterine endometrium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K28354175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48633
Adrenocortical carcinoma_ACC_TCGA-OR-A5JW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81109
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79746
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.763
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16702
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diminishes	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHLDA3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-664	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1123
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.24554
BRD-K77207661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20419
Mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
streptomycin-5837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36038
Hepatic Cirrhosis_Hepatic Tissue_GSE1843	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.38538
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05578
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.52094
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988316
WASF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871919
SNF8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06578
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01483
srf_20709909_hematopoietic_stem_cell_lof_mouse_gpl1261_gds3732	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.5953
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF2	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7944-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
differentiation	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.680069
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159135
STAT5B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23763017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10983
vorinostat-6179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YKT6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.87565
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52285987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21262
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.828852
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EIF2B3	Pathway Commons Protein-Protein Interactions	1.0	null
SLC30A9	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_BMS-754807_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176915
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24258
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955156
SCAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71104
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2304
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17479
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76865
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36359
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965791
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.50533
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957195
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842331
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520829
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1142
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875275
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.34008
NFIC	ENCODE Transcription Factor Targets	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20325
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SARS-CoV MA15_Day4-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.946641
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07201
Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34029
SNAPIN	Pathway Commons Protein-Protein Interactions	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08972
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829585
chr7_43895636_C_A_b38	GTEx eQTL 2025	1.0	1.94548
MAPRE1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.22457
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1650	CCLE Cell Line Gene Expression Profiles	1.0	1.65739
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.475772
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSBP	Pathway Commons Protein-Protein Interactions	1.0	null
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58107
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54284
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K95010912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23322
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16171
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	1.43173
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944254
USO1	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21244
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139948_3_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89858
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37451
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP1S	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833852
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86854
NELFE	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6941
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03265347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11649
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16674
trichostatin A-7285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92776249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34961
ANKFY1	Pathway Commons Protein-Protein Interactions	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75263760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60025
analyzedin	GeneRIF Biological Term Annotations	1.0	null
K562_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155251
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01642
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04706894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31741
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0665
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82229
carteolol-1340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48936
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.49195
BRD-K42008693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22516
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05273
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29073
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GOLGA7	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-27b	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
trichostatin A-4821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_8-ILL1_T_Cells_FOXP3_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
EIF2B5	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.95342
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-0.912766
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ES-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920345
STX5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75909618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44522
L428	CCLE Cell Line Gene Expression Profiles	-1.0	-2.67757
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46613
GOLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
ursodeoxycholic acid-3105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K61366105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56064
DDX11	MSigDB Cancer Gene Co-expression Modules	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72444
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03931
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.94511
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63049
BRD-K71554049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37618
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A90969585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69691
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30885
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46008
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10180613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0222
hsa-miR-877-3p	MiRTarBase microRNA Targets	1.0	null
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.834371
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970332
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.51036
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48004
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14567
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33619
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507416
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL54	CCLE Cell Line Gene CNV Profiles	1.0	1.48516
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.112
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44002
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48872
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.890797
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05166
TBP	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.35655
BRD-K73678117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38699
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02932
STX16	Pathway Commons Protein-Protein Interactions	1.0	null
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
eye	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09627
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNX4	Pathway Commons Protein-Protein Interactions	1.0	null
ALK_druginhibition_187_GSE50803	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44467
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68333
BRD-K98601267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19891
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52812
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.98376
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.517808
TRIM24	Pathway Commons Protein-Protein Interactions	1.0	null
PIN1	Pathway Commons Protein-Protein Interactions	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
EPHA2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07576
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91613
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04748
SNX9	Pathway Commons Protein-Protein Interactions	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664261
methotrexate-5419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-2.43022
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	1.79707
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37101
CEBPD	ENCODE Transcription Factor Targets	1.0	null
PMC2965092-pone.0013658.s001.xls-Liangos_SOM_Table1-GeneName_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11696795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48484
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66795
SKP1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00378498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71576
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54771
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06231
ARFGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04381
kawain-7369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05543
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140937,GSE140938_1_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
scriptaid-6896	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.899113
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.38885
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855388
BRD-K96623405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17192
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85912419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81005
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951474
BRD-K39153737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08534
Multiple personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0897
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45818
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22006
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06488
EXOC6	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053107
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509171
NRF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57615
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9489
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH292	CCLE Cell Line Gene Expression Profiles	1.0	1.53585
AP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.927005
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.829926
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08493
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08648
BRD-K61033092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67445
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20143
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39697
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08081
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846643
trichostatin A-7047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.594986
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36512
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HGC-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
BRD-K32208085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42061
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16329
Perturb_13802_KO_Mettl14_SRP286301	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.519518
KNTC1	Pathway Commons Protein-Protein Interactions	1.0	null
Bone sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34853
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944209
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52867
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936415
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67169
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1658
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	1.0	0.934449
LAMTOR3	Pathway Commons Protein-Protein Interactions	1.0	null
VIPAS39	Pathway Commons Protein-Protein Interactions	1.0	null
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08239
SNX27	Pathway Commons Protein-Protein Interactions	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70311
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55133
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02749944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64549
A549_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151328
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.78147
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16399
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.28727
TXLNG	Pathway Commons Protein-Protein Interactions	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13259
ERBB2IP	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
Perturb_3486_KO_Mettl3_SRP273291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
regulating	GeneRIF Biological Term Annotations	1.0	null
PLEKHA7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08075712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61621
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-7407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K46107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65546
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-1.57187
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.10581
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09062
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TK10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.936394
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07615
BRD-K26005379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10789
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9492
BRD-K98810653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45396
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.45672
trichostatin A-4483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CUX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889571
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03853
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45094
LN215	CCLE Cell Line Gene Expression Profiles	1.0	2.92124
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864901
K562_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155964
IQGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25485
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16133
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42982
OXSR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5B	ChEA Transcription Factor Targets	1.0	null
BRD-K06685815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.646
BRD-K07798964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03175
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25066
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-7005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Caov-3	GDSC Cell Line Gene Expression Profiles	1.0	1.54298
GNAQ	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244710_1_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887279
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08252
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20628
BRD-K11165361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28827
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
Childhood Hepatocellular Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17086
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	1.38956
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15902281-TableS1d	GeneSigDB Published Gene Signatures	1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
trichostatin A-5336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14245433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23382
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.110804
RAB2A	Pathway Commons Protein-Protein Interactions	1.0	null
VMRC-RCW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20402
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08368
WM2664	DepMap CRISPR Gene Dependency	1.0	2.04276
vinblastine-7551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65549
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K08009212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13241
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33791
BRD-K25423830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07577
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
trichostatin A-6551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OSBPL8	Pathway Commons Protein-Protein Interactions	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01281
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.374809
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26668
BRD-K11476310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21559
MITF	ChEA Transcription Factor Targets	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23765
effects	GeneRIF Biological Term Annotations	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.857913
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27388
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09058
BRD-K25147028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10793
BRD-K56241426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27735
CAV3_Deficiency_GDS3552_558_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18181387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32008
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.833699
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06212
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49825
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.51943
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indapamide-3778	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885229
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAMG	GDSC Cell Line Gene Expression Profiles	1.0	1.47851
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-K1-A6RU-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ARHGAP17	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926572
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.852745
naftifine-7032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BLOC1S5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20752
8305C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57702
TBX5	ChEA Transcription Factor Targets	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01792
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDCD4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
HAUS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1777
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54146
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11679
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.901601
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00042
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDFY3	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
BAIAP2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trichostatin A-448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K56024445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14054
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25895
RAB3GAP2	Pathway Commons Protein-Protein Interactions	1.0	null
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01935
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.7718
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75508
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5538547-supp_gr.217331.116_Supplemental_Table_S3.xlsx-DNA_and_CCF-Table_3_Frequency_of_genetic_alterations_determined_from_single-cell_DNA_and_RNA_analysis_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11082
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29852
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10657
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8365
Sarcoma_SARC_TCGA-DX-A8BX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06964
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ANKRD11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3026
SMAD4	ChEA Transcription Factor Targets	1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94049419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20669
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD-26-MB82_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308451
astemizole-1365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS26	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91105
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3653
meteneprost-7504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WLS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
minaprine-1968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOM1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824273
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846833
RHEB	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073988
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10234
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12305
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18115
carbamazepine-1683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04664
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.17861
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB17	Pathway Commons Protein-Protein Interactions	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01471
K562_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154278
proliferatoractivated	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-28-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TE4	CCLE Cell Line Gene CNV Profiles	1.0	2.47363
BRD-K23610423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68233
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMF1	Pathway Commons Protein-Protein Interactions	1.0	null
ncih1650	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09546
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07647
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.830706
NCIH1355_LUNG	CCLE Cell Line Proteomics	1.0	2.07149
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_9796_OE_Foxd1_SRP132362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
22RV1	DepMap CRISPR Gene Dependency	1.0	2.39451
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
SNX17	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64993
HGS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K68980973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52857
Colorectal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90122
CTCF	ENCODE Transcription Factor Targets	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-3189-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384508
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBGCP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00564
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.041841
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29508
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24786
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.71
viral hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.278297
PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978797
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876083
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36164005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49584
hsa-miR-4755-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846358
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932369
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01863
BRD-K76087207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23888
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.92465
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.33748
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
BRD-K36198653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.534
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51204
SMAD4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAN2	DepMap CRISPR Gene Dependency	1.0	2.18998
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
PF-00875133-00-5928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_1618_KO_Cebpb_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.8172
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.90359
PITPNB	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35987
STAM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44607
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFYVE1	Pathway Commons Protein-Protein Interactions	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56159
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
acid	GeneRIF Biological Term Annotations	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EXOC8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.022
BRD-K97540907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51595
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26161397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55463
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974756
CRCGN012_HEPG2_24H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22833
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGD3	Pathway Commons Protein-Protein Interactions	1.0	null
transcriptional	GeneRIF Biological Term Annotations	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
SEC61G	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846833
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62248885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29155
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.02919
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01688
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3343
STARD7	Pathway Commons Protein-Protein Interactions	1.0	null
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27538
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49722
trichostatin A-5417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
GOSR2	Pathway Commons Protein-Protein Interactions	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966684
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10226
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05248348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70493
USP8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K99038919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32416
mitoxantrone-5354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17801
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152637_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907761
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.89614
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8243
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GRIPAP1	Pathway Commons Protein-Protein Interactions	1.0	null
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34674
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937452
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2475
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CP-863187-7553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.13584
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15535
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39826
MCF7_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110383
BRD-K28349636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24703
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.055254
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11138
iopanoic acid-2965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K91683342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49637
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052493
SEPT14	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12066
BRD-K09261379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94641
Breast Cancer_Mammary Gland Tissue_GSE1378	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.90937
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887764
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.5539
BRD-K13279882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23375
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981794
GSE244710_3_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.237216
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04876
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33282
MET_knockdown_254_GSE38343	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.15389
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421529
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072825
dapsone-1868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
EPHB2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2741
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16225
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
VPS45	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09704
AP1G1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89772
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE192362_1_v_0_erastin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19579217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57304
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56337
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB20	Pathway Commons Protein-Protein Interactions	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.257289
DNMBP	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOF	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHMP6	Pathway Commons Protein-Protein Interactions	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Cervical epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64296795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19968
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SEPT8	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RIN1	Pathway Commons Protein-Protein Interactions	1.0	null
BC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.45781
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89525
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE1	CCLE Cell Line Gene Expression Profiles	1.0	2.20158
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347217
BRD-K12930517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09082
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27377
cell cycle	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33363
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058821
BRD-K48372955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76627
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57102
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09014
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.975913
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-SOX2-Unnamed_2_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484519
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
blebbistatin-954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K29820234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62031
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12339
BRD-K29662589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71819
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
RAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56184
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71418
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40156
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48837
BRD-K77324165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48017
BRD-K52037352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39325
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62466
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01166
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58113
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872318
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18349
GSE193282_3_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC70	GDSC Cell Line Gene Expression Profiles	1.0	1.71339
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64067
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89447678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16886
BRD-K98522669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36326
ZW10	Pathway Commons Protein-Protein Interactions	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21519
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
urg4urgcp	GeneRIF Biological Term Annotations	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08363
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.63486
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5258
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859134
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
HD-MY-Z	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01552
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199204,GSE211619_4_v_5_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.76318
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00286
hsa-miR-516a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09168812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69325
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73432
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33522
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860515
Perturb_6133_OE_Tfeb_SRP157662	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01593
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841561
BRD-K88662980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34483
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0721
clemizole-7371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270613
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34863
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82543
MAFF	ENCODE Transcription Factor Targets	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75073374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13766
BRD-K34739404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90108
NMC-G1	GDSC Cell Line Gene Expression Profiles	1.0	2.47676
cefotaxime-5830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976025
SEM	CCLE Cell Line Gene Expression Profiles	-1.0	-3.10187
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	0.825315
TRIM28	ENCODE Transcription Factor Targets	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SYNE2	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.974759
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
MOLT-13	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70697
MHH-CALL-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46962
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02351
GSE71972_9_v_10_histamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53133
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44579
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31666797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.081
azacitidine-4010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.79287
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66149
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOXIMVI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49423
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1147
BRD-K97339945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79938
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49362
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844486
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5282_KO_Ddx6_SRP137728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.48867
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.063448
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83562
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PK45H	CCLE Cell Line Gene CNV Profiles	1.0	1.35223
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Veliparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172295
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.551298
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58522
BRD-K54141134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82956
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951474
SIHA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REPS1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K63134971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34079
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1369
cycle	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colon	HPA Tissue Protein Expression Profiles	1.0	1.0397
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00638
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.16947
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12499
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0799
atropine methonitrate-6495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS12BM	CCLE Cell Line Gene Expression Profiles	1.0	1.37621
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.65009
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAR	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43253
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9881
hypertension	GWASdb SNP-Disease Associations	1.0	0.558127
SNX13	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13077
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79405
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58047
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.647
BRD-K09842906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42032
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10413
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.081
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26048
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AKR1C3-IN-1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.56
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47865468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00431
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50941200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81774
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1	Pathway Commons Protein-Protein Interactions	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13692
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0101178
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.349717
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81986
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACSBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38394
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41762
RAP1GDS1	Pathway Commons Protein-Protein Interactions	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388071
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8642
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900025
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12049
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955156
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.70319
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49796
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.585
peroxisome	GeneRIF Biological Term Annotations	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053596
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1904
K562_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225223
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48847
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAKI1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.3628
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20893
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.252397
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23155
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NMCG1	DepMap CRISPR Gene Dependency	1.0	2.50946
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.058082
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
PLEKHA5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K91085913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04793
SNU489	CCLE Cell Line Gene Expression Profiles	1.0	1.35858
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976586
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19475
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64026092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0924
Perturb_5145_KO_H3f3a/H3f3b_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71625
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607513
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8664
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963861
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966934
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959511
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14445
hsa-miR-27a	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.14291
ARF4	Pathway Commons Protein-Protein Interactions	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64277
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1708
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1708
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.00526
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K30201819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00149
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HA-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172108
isocorydine-1787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3297
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282679
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.906718
GSE144796_1_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23299
skbr3	HPA Cell Line Gene Expression Profiles	1.0	1.13616
JHH5_LIVER	CCLE Cell Line Proteomics	1.0	2.04404
flunixin-2552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826009
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40582
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841051
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAMP7	Pathway Commons Protein-Protein Interactions	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917444
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831505
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15475
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAMA-84	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89137
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.40829
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.2235
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0559
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PDZD8	Pathway Commons Protein-Protein Interactions	1.0	null
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123727
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993348
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989924
PKN2	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153581
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36343
NAPA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94998
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
trichostatin A-6546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MES-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01538
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K24614157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83932
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K14778436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07994
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33619
RAP2B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37738
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU5	CCLE Cell Line Gene Expression Profiles	1.0	1.87786
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K52194153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95429
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0655
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844228
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27753
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
trichostatin A-5802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14483
GTEX-REY6-1726-SM-48FDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21683
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
tinidazole-3430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05473
BRD-K28264750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48485
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SPC25	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58438
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2B	ENCODE Transcription Factor Targets	1.0	null
RB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05181
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905904
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-644	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2164
Prestwick-967-7346	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB21	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K79712504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2342
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867416
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
skimmianine-6242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12132
CHMP1B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16156
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957163
SIGMAR1	Pathway Commons Protein-Protein Interactions	1.0	null
VPS16	Pathway Commons Protein-Protein Interactions	1.0	null
UTP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06148
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09918
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35324337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38915
hbx	GeneRIF Biological Term Annotations	1.0	null
A549_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135247
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41997
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
SK-OV-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63036
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05099
Sieve plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
foxo3a	GeneRIF Biological Term Annotations	1.0	null
RABL3	Pathway Commons Protein-Protein Interactions	1.0	null
gtp binding	GO Molecular Function Annotations 2015	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2966-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859346
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01033
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53196
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28409
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0823
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00472
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	6.99771
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38384
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52244
RUFY1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32593
BRD-K14673075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2361
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49923205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68688
BRD-K74873856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43237
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15151
BRD-K69031148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49621
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1646
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37382
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
VPS29	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.00676
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ML221	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.83
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20384
5637 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TPX2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLC-PRF-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04539
Lung squamous cell carcinoma_LUSC_TCGA-85-6561-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC-44	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C3A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30365
ATP6V0D1	Pathway Commons Protein-Protein Interactions	1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	12.9309
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916957
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46439376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53144
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90093
SYNJ2BP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976891
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.908
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14653235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64918
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K35826866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50146
autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.372587
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Ofloxacin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150628
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57096
progesterone-4992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2477
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1394
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lncap	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884385
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06746
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4802
TAP2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04789
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898459
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977527
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAB5C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40300525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68308
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFRC	Pathway Commons Protein-Protein Interactions	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.37168
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0213	CCLE Cell Line Gene Expression Profiles	1.0	1.79524
ELMO3	Pathway Commons Protein-Protein Interactions	1.0	null
OSBPL11	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_12571_KD_YBX1_SRP262465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.96833
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE10_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	4.00054
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48665
K562_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186605
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11717
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cobalt chloride-379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT5A	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD2	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.94627
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051086
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855393
MCF7_Filgotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146363
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015958
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3137
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4925
A549	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.85244
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57526
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRAF2	Pathway Commons Protein-Protein Interactions	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2341
BRD-K84874502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53282
7519_RPS28_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.03856
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977397
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50084
rapamycin	GeneRIF Biological Term Annotations	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
ABR	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
IGROV1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.29459
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35156336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23013
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17199106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00593
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450359
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31005
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BLOC1S6	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K58944125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18638
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT16	DepMap CRISPR Gene Dependency	1.0	2.0693
TBC1D9B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53127464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12928
PRKAA1	Pathway Commons Protein-Protein Interactions	1.0	null
K562_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162206
CDC42BPG	Pathway Commons Protein-Protein Interactions	1.0	null
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT116_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.41623
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
etofylline-1409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-0.861139
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32256
IRF9	Pathway Commons Protein-Protein Interactions	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL5A	Pathway Commons Protein-Protein Interactions	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.5539
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.465
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7514
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TJP1	Pathway Commons Protein-Protein Interactions	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14465
BRD-K18978916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.903
BCL3	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08643
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35578
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0691
BRD-K43295075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13466
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886805
HEC251	DepMap CRISPR Gene Dependency	1.0	5.15955
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10793
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27328
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2011
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3533_OE_HLAG_SRP386253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14525
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU324	CCLE Cell Line Gene Expression Profiles	1.0	1.37385
SPECC1L	Pathway Commons Protein-Protein Interactions	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01554
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62342
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13113551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91067
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5006
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
GNAI1	Pathway Commons Protein-Protein Interactions	1.0	null
MYO7B	Pathway Commons Protein-Protein Interactions	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	2.20596
RMGI	DepMap CRISPR Gene Dependency	1.0	2.3169
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60662
PITPNM1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40760168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69423
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440228
KYM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30411
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865908
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994999
NCIH1915	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21982
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08056
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30921
ROCK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1973
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.30491
BRD-K84693638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20164
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04581
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4587
SNU398	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45818
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49006
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABL6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01889
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.02408
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	6.5859
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00748
HCC15_LUNG	CCLE Cell Line Proteomics	1.0	2.68521
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047943
BRD-K33752391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61715
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NI-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_S-Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124401
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6491
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981203
Perturb_15642_KD_Sf3a1_SRP043160	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58785
IQGAP3	Pathway Commons Protein-Protein Interactions	1.0	null
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.929
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9068
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48617
A549_AMG-900_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118794
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52536
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847728
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05985
Perturb_4317_KO_Fmn2_SRP109283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.4321
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642561
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51398
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90428
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06891
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07332
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53BP2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4	ChEA Transcription Factor Targets	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CADPS2	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1923
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.89597
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270406
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25123
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K66253165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1266
BRD-K74755318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28261
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051363
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.84156
PITPNA	Pathway Commons Protein-Protein Interactions	1.0	null
SCFD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844224
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0912
MM1S	DepMap CRISPR Gene Dependency	1.0	4.28436
VAMP8	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R1B	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896681
BRD-K38969544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70772
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26279
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SACM1L	Pathway Commons Protein-Protein Interactions	1.0	null
QD-32-CW16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203925
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909178
BRD-K39222068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23139
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05425
TTC19	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64431
nordihydroguaiaretic acid-1164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
interference	GeneRIF Biological Term Annotations	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5211
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52785
trichostatin A-6784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.32459
GOPC	Pathway Commons Protein-Protein Interactions	1.0	null
ZWINT	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28803
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29073
ABI1	Pathway Commons Protein-Protein Interactions	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908187
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
USH1C	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7776
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-16-KY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285355
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23579
aciclovir-1960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCAMP4	Pathway Commons Protein-Protein Interactions	1.0	null
DIDO1	Pathway Commons Protein-Protein Interactions	1.0	null
TNK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50477983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39532
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
CEP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03167
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1691
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937603
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18714
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82164
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941046
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SGK3	Pathway Commons Protein-Protein Interactions	1.0	null
RAB9A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994742
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70488
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03622
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.052152
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.460755
staurosporine-312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139461
MCF7_AG-490_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201527
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156312
guanyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09792
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K21285405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1715
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08809
BRD-K18345677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51986
BRD-K16268355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10932
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59067
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850491
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49532
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_DN_NR2F1_ind_DN-NR2F1_Ind_DN_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
WM793	CCLE Cell Line Gene Expression Profiles	1.0	2.2792
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73993
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984835
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19273
MELK_druginhibition_186_GSE50227	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.80786
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71104
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26985
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.5118
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42837
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SHB	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18714
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23792
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922273
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81894
effector	GeneRIF Biological Term Annotations	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039433
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51085
LU-65	GDSC Cell Line Gene Expression Profiles	1.0	1.53694
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2874-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1185
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45455
HOOK2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86240647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49021
SAOS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.33
BRD-K79908599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96813
K562_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163459
DOPEY2	Pathway Commons Protein-Protein Interactions	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.562042
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
fluoxetine_mus musculus_gpl1261_gse35763	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10515
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154577_2_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902692
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45521
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907968
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02631
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATR	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemogenesis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10132
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	3.82086
HARA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32061
MCF7_PF-573228_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128846
BRD-K28846321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14682
ERG	ChEA Transcription Factor Targets	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33997
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
valproic acid-1665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78224
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HNF4A	ChEA Transcription Factor Targets	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.8896
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51934291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93901
VPS4B	Pathway Commons Protein-Protein Interactions	1.0	null
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
monorden-953	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
pc3	GeneRIF Biological Term Annotations	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01414
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARHGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.067809
Precatalytic spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.686
BRD-K00086692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36455
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAF-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16938_OE_Prkag1_SRP162537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.75986
TBC1D4	Pathway Commons Protein-Protein Interactions	1.0	null
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102996
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967143
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26868
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.18027
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.997356
PTPN9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79847
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19803
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81V-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24857
11-deoxy-16,16-dimethylprostaglandin E2-7538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRAPPC3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH3122	DepMap CRISPR Gene Dependency	1.0	2.52444
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16884266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02002
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60452
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.159076
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97076
BRD-K76611906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.80298
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04389
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010635
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55468
BRD-K34519313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33521
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854396
Thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
MYLK_knockdown_49_GSE14525	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.19456
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	2.34687
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06899
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55883
valproic acid-2700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02240568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71695
sirolimus-1059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.92888
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.51305
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5154_KO_Dcr_SRP038929	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.9034
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARAP1	Pathway Commons Protein-Protein Interactions	1.0	null
imipramine-1849	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26775
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02082
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ARAF	Pathway Commons Protein-Protein Interactions	1.0	null
Endometriosis_Endometrium_GSE6364	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.30488
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKT1S1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NAPG	Pathway Commons Protein-Protein Interactions	1.0	null
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19614
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862085
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06900263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28699
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94967
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16106
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22654
BRD-K85044233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23777
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
SNU398	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79673
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91983
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990325
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.333583
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90965240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22797
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60862683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61658
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27989
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04712
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.226
BRD-K12223973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43159
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23587
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39725
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
after	GeneRIF Biological Term Annotations	1.0	null
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976052
gastric	GeneRIF Biological Term Annotations	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	2.19686
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869904
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIFLUPERIDOL-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73509
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14494
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844678
Perturb_6177_KO_Bmal1_ERP113681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32567
appendices_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.827175
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3287
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21062
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
FAM21A	Pathway Commons Protein-Protein Interactions	1.0	null
M07E	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62565
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4659
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908481
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08972
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04123
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09573
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16469
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31515
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6445
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35913
BRD-K32082369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71223
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.56655
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1706
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DGKQ	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03883
TBC1D10B	Pathway Commons Protein-Protein Interactions	1.0	null
PCYOX1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56616847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58289
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14995
guanyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K24206299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96857
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0358
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.900403
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986804
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
Stage, Cervical Cancer	DisGeNET Gene-Phenotype Associations	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935123
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2179
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33542
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A33	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874044
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.949354
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38278
BRD-K38917645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62053
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60583
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052056
MAP2K2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60830482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.102
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79516
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42094
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
HGC27_STOMACH	CCLE Cell Line Proteomics	1.0	10.5592
PPM1A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47449
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89048
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54856
SH3GLB2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35545
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94331
estradiol-6200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99482176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79234
gefitinib-541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7323
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08482
BRD-K36149853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67198
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26147
SNU475	DepMap CRISPR Gene Dependency	1.0	2.84597
hsa-miR-4689	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59192
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19223
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679892
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.314
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
organelle	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRBA	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SFT2D3	Pathway Commons Protein-Protein Interactions	1.0	null
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45629
HLA-B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936359
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81592842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37301
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
absence	GeneRIF Biological Term Annotations	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.91156
BRD-K40982265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22077
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59778279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72337
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15005
Nasopharyngeal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79405
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85868
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31571
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124683
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911698
OVCAR8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53669
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glioma	DisGeNET Gene-Disease Associations	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874127
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170576
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42475945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3909
BRD-K82823857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5597
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95171874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96784
PMC9314667-Table_1.xlsx-Regulons-SOX9_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03862
BRD-K46924722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48156
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88976
GW-8510-7080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22374
du-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401007
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K36627718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94396
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
BRD-K56437119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09337
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM2313	BioGPS Cell Line Gene Expression Profiles	1.0	1.4076
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897265
KIAA1033	Pathway Commons Protein-Protein Interactions	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683949
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423054
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30495
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
SEPT10	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1087
BRD-K84821804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68388
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951319
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89574562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23635
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_AICAR_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128676
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32074
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898393
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13772
BRD-K17858048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27464
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04452
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03397
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73318
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98078
BRD-K16891407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39323
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880031
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837164
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K63909265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50241
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1646
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887688
rna	GeneRIF Biological Term Annotations	1.0	null
BRD-K54351451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02196
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAAA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08981
E2F6_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15827
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03984
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28941
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOF	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6067
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59049030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94052
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09375
Lung squamous cell carcinoma_LUSC_TCGA-85-A50M-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58307
BRD-K47337578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60818
MFE319	DepMap CRISPR Gene Dependency	1.0	3.00653
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5932
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21449
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03625
STAT6	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07451
LU99	DepMap CRISPR Gene Dependency	1.0	5.28758
GTEX-Q734-1426-SM-48TZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978739
BRD-K32853527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09808
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K67442425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19017
BRD-K65789952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64296
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14823121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1786
BRD-K67980010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21287
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234298
BRD-K92955882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.51894
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33777
BAZ1B	Pathway Commons Protein-Protein Interactions	1.0	null
17880687-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PDCD6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13585
STX7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13941052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05094
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70588
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83076
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070686
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940186
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.888961
6-benzylaminopurine-2351	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB14	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24863
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.66507
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
BRD-K07013504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53041
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMSCTR	DepMap CRISPR Gene Dependency	1.0	4.90067
BRD-K23817660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.35062
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K33257311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44025
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03686
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18701
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48079
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.54446
RPS6KA4	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-1421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63694
CRCGN011_HEPG2_24H:C17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0659
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34423
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53112
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00096
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J6-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69048559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87476
BRD-K98934548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53049
ATP6V1E1	Pathway Commons Protein-Protein Interactions	1.0	null
LAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41347678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25834
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39914
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.90428
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124277
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79759
all	GWASdb SNP-Phenotype Associations	1.0	0.031325
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRCH4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9778
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15005
TTI1	Pathway Commons Protein-Protein Interactions	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2805
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03478
BRD-K61522760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12908
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.66507
DST	Pathway Commons Protein-Protein Interactions	1.0	null
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K92581247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07749
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946875
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16997
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K62184784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56379
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K09166899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24594
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13697
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HLA-C	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27671601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70748
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17463
PHF8	ENCODE Transcription Factor Targets	1.0	null
etanidazole-2510	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35847
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23195
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58426
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEU1	Pathway Commons Protein-Protein Interactions	1.0	null
profile	GeneRIF Biological Term Annotations	1.0	null
BRD-K39449072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47408
ATF3	ENCODE Transcription Factor Targets	1.0	null
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92978
BRD-K43981353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06345
BRD-K79937734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70167
ECC12	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94064
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70725
Parametrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28576
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00804
epithelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:M06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12155
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIF-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08583
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26768
WM793	CCLE Cell Line Gene CNV Profiles	1.0	1.45234
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24681
Chicago Sky Blue 6B-4971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28916436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02904
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12929741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37201
HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25418
BRD-K17059629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21339
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.50082
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31276
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VRK1	Pathway Commons Protein-Protein Interactions	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53492
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VAPB	Pathway Commons Protein-Protein Interactions	1.0	null
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64995
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74159
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993876
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-3689f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18856
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60905563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29042
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2063
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.35412
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70868
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26967
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
MAPK7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51573654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80869
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42315
Perturb_5242_KD_Eif4a2_SRP261876	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8304
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K73166462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11861
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31945
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921936
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69199
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853469
OSBPL10	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176779
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946226
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02378
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16788
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87678
NRF1	ENCODE Transcription Factor Targets	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263953
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03714
tamoxifen-380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40E-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical Cancer	DisGeNET Gene-Disease Associations	1.0	null
BRD-K31721388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26596
Uterine adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46159
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6072
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2913
CCND1	Pathway Commons Protein-Protein Interactions	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43287
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62979
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GDI2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K71427375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33058
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897199
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23598
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.25879
MTA3	ENCODE Transcription Factor Targets	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8153-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863332
GOSR1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858089
TGIF2LY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75684
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.556732
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-48-MBD2_MBD2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29903249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21552
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAA	Pathway Commons Protein-Protein Interactions	1.0	null
RAPGEF4	Pathway Commons Protein-Protein Interactions	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.36062
BRD-K13922961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11113
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
DOCK6	Pathway Commons Protein-Protein Interactions	1.0	null
RS4-11	GDSC Cell Line Gene Expression Profiles	-1.0	-3.04219
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4303	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
TRAPPC4	Pathway Commons Protein-Protein Interactions	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54831
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
K562_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145443
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900714
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052956
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.911037
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02258
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22422
BRD-K48780709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84596
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083468
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03818
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13488
pc-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33965
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10014
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73421
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13406
single-organism process	GO Biological Process Annotations 2015	1.0	null
STX17	Pathway Commons Protein-Protein Interactions	1.0	null
Adenocarcinoma of lung_Lung Tissue_GSE11969	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.32396
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852563
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99545
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92712671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53964
STAT1	ENCODE Transcription Factor Targets	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.992284
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3468-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23541
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
L-428	GDSC Cell Line Gene Expression Profiles	-1.0	-1.81642
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31867
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61739
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10064
BRD-K37850190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05523
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
importantly	GeneRIF Biological Term Annotations	1.0	null
prognosis	GeneRIF Biological Term Annotations	1.0	null
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143267
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.816123
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25228
BRD-A23434937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11921
vorinostat-1645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12583
STARD5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0289
ARHGAP18	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.24623
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1369
associate	GeneRIF Biological Term Annotations	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28258038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68377
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.557263
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ING1	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K88467167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41806
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K95763144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0924
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAOK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064021
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41906
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02258
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53934
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959951
selegiline-2465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBE2Z	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21666
MCF7_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25555
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NMCG1	CCLE Cell Line Gene Expression Profiles	1.0	1.71708
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961981
MOB1B	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null