association	dataset	threshold value	standardized value
DE-99-OT37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369463
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AB-01-UY50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.894026
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-00-HF91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21079
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4450	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2435
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22128
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563571
ED-71-GA72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217433
BB-27-MC77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42589
XD-03-FM54_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229105
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18201
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.99735
EF-33-QP63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294113
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53301
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OC-55-QZ56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203178
ME-77-XX06_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.501244
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JE-61-EQ70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.58799
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.94986
FF-55-AD09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.49782
ZEB1	ENCODE Transcription Factor Targets	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37838
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10506
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-15-VH74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.541996
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.542113
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.626849
HNF4G	ENCODE Transcription Factor Targets	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB-94-ZA83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393437
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.65375
AA-62-HP31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254621
QC-10-TY16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.824938
DE-58-OW37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384045
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.826801
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236639
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.112
HC-04-ZM18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262948
PF-39-DY68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208482
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22284
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-05-XP37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326014
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1278
ID-00-IC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376842
overnutrition	GWASdb SNP-Disease Associations	1.0	0.473391
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.834707
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.32495
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279818
MAFK	ENCODE Transcription Factor Targets	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14906
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91435
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73732
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89117
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-91-WE67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259719
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	210.149
DD-47-GB64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261997
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.511795
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496073
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-97-VE31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.453927
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.4895
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12272
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1059
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47436
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.14724
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38839
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.4197
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965251
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.49086
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YE-46-YA12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310213
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.7462
EGR1	ENCODE Transcription Factor Targets	1.0	null
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.16965
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.81895
AC-75-LR63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39868
EE-32-EY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3709
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-84-DG64_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388594
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56701
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21292
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251068
MF-81-RJ18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214553
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67314
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26833
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523117
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.9915
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73934
USF2	ENCODE Transcription Factor Targets	1.0	null
AD-18-XC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486985
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.16252
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.590015
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-15-YU05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323088
AB-35-RU30_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.320341
DF-00-BX35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26426
PMC9229595-Table_2.xlsx-LPS_subset_IX-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.941529
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16935
ZEB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-01-DO31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259179
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.207
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-73-HJ84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215934
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78556
BC-62-RZ55_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319885
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.21402
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.803794
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-80-OD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262883
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.959509
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2412
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474325
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246102
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.8958
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.8638
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.615503
RXRA	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OC-55-QZ56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254223
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SB-28-EJ14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14061
AD-89-ID99_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262234
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75639
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-86-KF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386731
AA-24-UO04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20067
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1393
BE-69-RD44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347175
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.16168
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50404
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79516
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323862
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.46505
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.38423
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.911694
JUND	ENCODE Transcription Factor Targets	1.0	null
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64851
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86854
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.6885
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955387
HB-06-WU12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309284
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.879716
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.45777
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383134
SB-28-EJ14_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353626
FB-85-ND09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438368
EB-67-WB79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209245
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.76033
CE-95-YX02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200112
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66172
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8162
FB-85-ND09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284889
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334678
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.21455
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50343
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AA-46-GL76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295833
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3055
HN	CCLE Cell Line Gene CNV Profiles	1.0	2.5423
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-48-VW67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.478358
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951686
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951686
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.885376
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.651504
CB-55-AK76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.716947
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325957
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	1.00407
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.50162
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38839
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06968
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.296483
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5762
AC-10-JK64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200706
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04145
WM793	CCLE Cell Line Gene CNV Profiles	1.0	1.45234
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YD-21-ZR41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214108
obesity	GWASdb SNP-Phenotype Associations	1.0	0.882984
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.17456
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75544
NB-24-VE53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202394
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02774
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20625
PD-26-DC63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212515
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960686
GA-47-MH68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282964
USF1	ENCODE Transcription Factor Targets	1.0	null
AE-32-DP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.918641
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981132
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.36062
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.66507
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-73-BW50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365608
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.335
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31875
AA-68-OJ16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269325
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-01-UY50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.01846
DD-95-TY80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245558
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299165
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8181
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185744,GSE185747_0_v_4_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.33748
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94921
CC-55-CD84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34033
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9487
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322615
ELK1	ENCODE Transcription Factor Targets	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.60378
JA-85-SW39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226163
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.59555
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70178
ETS1	ENCODE Transcription Factor Targets	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07088
CAL-54	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.35555
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	160.252
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285391
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.7185
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0415
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.49529
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.40113
H4	CCLE Cell Line Gene CNV Profiles	1.0	2.15631
HARA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32061
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-81-DS26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.531655
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-31-GO06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273016
EC-86-EK93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.960351
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.23557
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38005
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-67-WB79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224386
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42002
OE-31-YC41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263474
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.55679
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854669
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.93652
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02279
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.3485
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-55-AD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.47628
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836836
GSE111247_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02912
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406146
HMGN3	ENCODE Transcription Factor Targets	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5666
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BB-64-EE60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264514
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4283
ED-81-ZH14_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374473
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-55-AD09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29327
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.70353
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.791
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26833
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.61816
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52096
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887422
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280964
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JA-88-IO52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.02625
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12106
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.9309
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85788
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-42-FF52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32446
BC-36-PL31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251573
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
PC-18-VX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310804
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46712
ARID3A	ENCODE Transcription Factor Targets	1.0	null
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83869
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56167
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.78727
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24569
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.63834
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-39-ED84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.925956
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76851
CREB1	ENCODE Transcription Factor Targets	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68056
PF-39-DY68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.332912
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02431
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-12.0052
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23809
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.78491
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58456
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.21244
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863477
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85688
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267049
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59914
CHD1	ENCODE Transcription Factor Targets	1.0	null
KA-37-GD83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243168
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52113
PE-86-SC73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363431
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05548
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-98-TQ46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370463
AB-12-PP61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.549794
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
AA-24-UO04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3066
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.795984
IB-30-KN41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642086
CB-25-VR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439053
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0249
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53196
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219398
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70411
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.99937
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	1.79707
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7065
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49024
TAF1	ENCODE Transcription Factor Targets	1.0	null
PC-18-VX23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.433631
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41107
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26833
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02832
CB-55-AK76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207169
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HE-16-PO98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.702237
GA-77-MH38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304175
S0-EE-XGII_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255065
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272635
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.16108
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03937
SB-94-ZA83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36443
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253609
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462487
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850174
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31244
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.8194
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.4546
GA-77-MH38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26804
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872473
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
NB-24-VE53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361746
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03073
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201697
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.84188
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203812
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.84965
JC-63-BE61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343424
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07536
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0904
FOS	ENCODE Transcription Factor Targets	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.414949
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4602
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00662
RA-86-LI22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265298
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903669
DE-01-HO61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217537
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232924
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922141
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
OE-41-RC56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222229
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RA-49-ZB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.530981
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49024
HDAC1	ENCODE Transcription Factor Targets	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72486
BF-94-NX85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365111
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-19-VU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224255
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37838
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.579
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26688
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.45822
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13377
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218211
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00189
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.928939
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.03322
BB-79-AG41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.869935
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529604
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846495
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640421
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400843
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.54053
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11557
AC-10-JK64_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.529963
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55904
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-92-JL46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486742
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.73697
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08954
KA-63-FH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479345
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
XA-82-BM12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.412889
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-10-JK64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.553849
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.61042
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RC-52-AC88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526594
CE-15-YU05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280034
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28684
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71663
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.774
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	7.10808
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846495
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-94-QJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342199
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-28-SS67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.948619
AA-87-EI21_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208597
AD-42-US78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246452
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-67-WB79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233074
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-11-GB40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.653843
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29863
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-25-UR78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.505935
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.948211
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-29-PY58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478319
DE-99-OT37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202591
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227545
AA-94-TU18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248392
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5495
AD-55-WK61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370263
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.188432
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
QC-10-TY16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.411958
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HB-92-XE24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395133
BB-27-MC77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.481662
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-44-GQ28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.516052
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25533
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877962
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.516326
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.887079
BF-10-IO69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237948
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-85-OX77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247562
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948381
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318617
BE-69-RD44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.674063
CC-55-CD84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.870096
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0091
AB-44-GQ28_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.974862
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492964
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41567
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70458
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980674
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.499
BD-22-KS33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366407
JA-88-IO52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00591
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08856
PK45H	CCLE Cell Line Gene CNV Profiles	1.0	1.35223
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-15-YU05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.510435
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.78329
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.45114
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-10-HD17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246749
GA-47-MH68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282733
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.63486
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93269
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.5817
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.16642
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-31-GO06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.500103
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.721357
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38156
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TD-48-XJ84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286151
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5354
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.7624
GE-98-ZI68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.538103
OB-20-LP90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266515
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.49965
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-55-XA97_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424277
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
TCF3	ENCODE Transcription Factor Targets	1.0	null
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.49195
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17951
FD-59-TC81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.695203
AB-44-GQ28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.841097
GB-96-WX99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353748
AA-79-SX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.383185
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15244
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-15-HD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336072
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08856
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06894
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.39329
DC-23-UM36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307522
CB-44-RT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342891
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04229
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.850898
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528305
NB-24-VE53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.476534
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8639
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4893
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210046
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935262
OF-98-RK57_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273379
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
QA-98-TQ46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475056
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
AB-35-RU30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339724
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BF-61-BY15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246669
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63203
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.536868
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.24996
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955387
AE-05-CB45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.30536
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859224
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64933
YA-85-VH07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299843
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YE-46-YA12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.565949
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850174
S0-EE-XMWH_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31135
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1492
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.603921
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284888
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AF-73-HJ84_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.639168
CC-70-BD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.593646
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.961946
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.646501
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-97-VE31_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350949
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568398
ED-15-OX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216012
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89078
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.06886
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83158
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22853
AA-24-UO04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.639984
JA-23-QE71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254215
AB-01-UY50_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.389
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.76783
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6466
DE-73-JX23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21284
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75639
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742877
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82359
NCIH2052	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38026
QA-34-PH05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369721
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ID-70-SM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248855
BA-88-HT15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316564
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.11504
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13779
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-25-UR78_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219396
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
BE-16-VM54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372056
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03606
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.26755
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.547612
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.8184
MYBL2	ENCODE Transcription Factor Targets	1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.51305
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GD-63-XB79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341576
AA-01-JO26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258122
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.52589
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43509
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846495
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.85601
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-72-YW56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19418
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.685037
GB-46-CK08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246581
SNU398	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45818
CHD7	ENCODE Transcription Factor Targets	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850174
QA-98-TQ46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407396
XA-82-BM12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247734
MXI1	ENCODE Transcription Factor Targets	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.88867
PMC8914074-Table1.XLSX-S8-Alternative_splicing_events_from_corneal_epithelial_samples_and_peripheral_blood_samples_of_KTCN_patients_VSX1	Rummagene Transcription Factor Associations 2026	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.61682
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61123
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-93-RP38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271673
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.66507
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.854772
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3733
AC-95-TK81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218494
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4333
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-11-SS01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230462
CAL54	CCLE Cell Line Gene CNV Profiles	1.0	1.48516
TAL1	ENCODE Transcription Factor Targets	1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601588
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04482
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43381
AD-18-XC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.456297
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36272
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246832
HC-86-IA49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247592
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327545
TAF7	ENCODE Transcription Factor Targets	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.85817
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681152
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MD-91-JM80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265248
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.92924
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11577
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87455
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836836
AC-93-LT43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523277
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5696
RAD21	ENCODE Transcription Factor Targets	1.0	null
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.695996
BC-33-BM51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475373
JE-61-EQ70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.04982
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59271
UBTF	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22874
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218626
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273315
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.979762
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986246
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20086
DE-37-JV37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229377
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-98-HX85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201378
hsa-miR-662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.527624
DE-48-HZ49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413898
SIN3A	ENCODE Transcription Factor Targets	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.911102
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.86291
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33996
PMC7825356-8844261.f3.docx-10-ZFHX4_ZFHX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-79-ZF28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267248
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9959
WF-85-JN16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26099
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432177
POLR2A	ENCODE Transcription Factor Targets	1.0	null
AA-62-HP31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.683949
ZB-16-BR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456318
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WA-03-IF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220915
all	GWASdb SNP-Phenotype Associations	1.0	0.029064
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.3077
YE-80-LN04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465899
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295207
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.51943
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207956
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.55349
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01044
GTF2B	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ED-02-CL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.700953
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-46-GL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216996
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-81-IV73_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278765
BB-48-VW67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293011
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7114
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323323
JA-88-IO52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.50331
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00845
ZNF384	ENCODE Transcription Factor Targets	1.0	null
CB-82-PL01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.863589
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228326
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.72982
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983043
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56131
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.496493
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13221
RA-49-ZB08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208504
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.893174
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OA-74-FH10_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214784
AA-62-HP31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.575294
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49737
BCL3	ENCODE Transcription Factor Targets	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
FA-89-PW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.874161
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.618041
GA-77-MH38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.672088
BB-27-MC77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.908696
GF-90-DG49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207495
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245947
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.29439
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568839
GA-79-ZF28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.816925
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.2405
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
S0-EE-YMWJ_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507392
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224334
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.118357
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-86-EK93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.507897
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BB-32-IZ10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369124
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-16-KA99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215386
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.193
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54882
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35075
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.65275
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5447
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-8.30147
EZH2	ENCODE Transcription Factor Targets	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08856
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18047
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58319
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
WC-33-YP46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389963
AD-51-SS86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38219
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31796
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00565
GSE185744,GSE185747_0_v_1_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
NE-37-BQ24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358088
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-9.57804
CB-32-EI69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226394
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04117
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.78147
MA-32-UX14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26203
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HE-16-PO98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374458
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08856
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94076
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8095
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674883
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2301
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26734
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43758
CHD2	ENCODE Transcription Factor Targets	1.0	null
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17057
POU2F2	ENCODE Transcription Factor Targets	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81014
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.25669
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01138
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.422
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82435
NB-80-IM48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338611
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
8305C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57702
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0971
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27376
DC-51-WE27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.3392
BA-60-RH02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238793
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.242789
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74646
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334713
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.839793
GSE162575,GSE162609_5_v_4_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-06-MO73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232645
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-71-LY65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.595173
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4643
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VF-06-RV33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230655
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.656086
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0444
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7809
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-96-WR45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216037
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.462668
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.878177
DA-10-ZX00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371427
STAT3	ENCODE Transcription Factor Targets	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.95261
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-27-MC77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.518567
AB-84-PK04_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.457943
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11158
KE-47-IA01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.457252
EB-82-HZ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440046
PE-86-SC73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206485
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02664
PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XE-69-AT35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287708
QB-87-TC65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.513013
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.4725
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6578
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-10-SB73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354195
CE-20-VA70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23728
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.882347
KA-58-YE68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3022
AB-12-PP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342347
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-73-HJ84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.553337
AC-31-PL89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.45994
FC-85-OX77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219992
QE-98-XD90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351484
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43885
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207826
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458339
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86086
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
JA-88-IO52_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.94875
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.361
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49112
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412709
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286859
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877062
AF-30-GH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.912235
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220238
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846495
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QB-87-TC65_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27481
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18508
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207575
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
DC-22-OP01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486629
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FB-24-UT80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36158
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13779
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6075
BRCA1	ENCODE Transcription Factor Targets	1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.599254
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32623
AD-43-XJ59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30003
TE4	CCLE Cell Line Gene CNV Profiles	1.0	2.47363
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02311
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920113
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744716
PF-59-CY33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.61629
PML	ENCODE Transcription Factor Targets	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MF-81-RJ18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262915
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252675
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51747
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.781807
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.449
AF-12-IW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414098
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29961
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32845
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950329
DD-15-VH74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.63597
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11221
DB-73-BC12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293294
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.12575
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60615
TA-57-FF07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209544
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-92-JL46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258507
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87189
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200184
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.23914
JA-85-SW39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0701
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890748
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438337
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0149
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.37549
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00691
NC-01-ET52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.337582
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.54828
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23936
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.96175
YB-58-IZ37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340436
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YD-21-ZR41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334072
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.898149
hsa-miR-3679-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830527
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.95255
EF-52-ML96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203217
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MF-81-RJ18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406459
MAZ	ENCODE Transcription Factor Targets	1.0	null
HC-76-HU27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202942
AB-00-IL62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482684
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-90-YR46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288925
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HC-86-IA49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.346694
JE-61-EQ70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.39269
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37627
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-55-CD84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.64014
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35661
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30324
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418806
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.927451
BRD4-28847988-BCBL1-HUMAN-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509127
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.13339
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.13196
HD-99-BT62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22816
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6551
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29968
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05959
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26163
AC-91-WE67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263566
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-43-XJ59_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.426199
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11123
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-42-US78_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.510834
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100557_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07926
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
ELF1	ENCODE Transcription Factor Targets	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360631
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.89162
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.881326
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34029
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.80236
GA-04-JM33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295029
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529612
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.882984
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7607
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.326
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.40381
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	251.609
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.386
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE-78-XD40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233669
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00409
FD-62-ZB67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.580546
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951686
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23454
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270287
CE-18-CG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227023
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.15868
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02333
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983043
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA-22-CY42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249539
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314165
KA-58-YE68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400633
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-03-PW00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.500238
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.938163
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.9639
PMC7373278-pone.0236187.s013.xlsx-MCF7_genes_overexpressed_in_AR-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-55-GO91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249003
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33811
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.55469
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.10234
KB-78-BE93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.937029
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.6388
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1006
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-57-HV87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263538
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.78713
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.52206
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.52111
PF-39-DY68_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252636
MD-86-UW46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30474
SB-94-ZA83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278194
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.697246
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB-24-VE53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365098
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
DD-73-IP88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219242
JE-61-EQ70_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.291738
EA-02-ZO63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28639
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0672
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.24823
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.217
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CC-47-VS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316774
disease	GWASdb SNP-Disease Associations	1.0	0.025361
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.53038
IC-72-TE79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29848
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54245
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BA-19-VU85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223104
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73199
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295833
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.58478
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.359537
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-77-XX06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312048
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.91247
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667541
FF-34-KW62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.728708
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
TA-57-FF07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253823
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35811
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XD-08-ZW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284815
Peak insulin response	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52276
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-05-CB45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400322
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-11-LL59_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246012
BE-69-RD44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394924
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665717
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674965
JC-63-BE61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246809
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31998
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250923
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-84-TD72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25655
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.748101
E2F4	ENCODE Transcription Factor Targets	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02311
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901175
VC-19-YG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340701
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.3819
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46757
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.725533
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365419
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4491
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
EC-86-EK93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310662
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60664
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-49-EJ23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352214
HA-30-KD77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232305
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.532
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.93536
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4662a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213848
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21057
AC-75-LR63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213291
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9894
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
RA-49-ZB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232354
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11056
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.47434
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16752
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295809
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17223
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472406
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DD-15-VH74_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.384422
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BF-61-BY15_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347581
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5996
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60579
FC-88-AJ86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229062
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XD-44-FJ34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416775
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.449
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1492
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.605563
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.37762
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38839
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09459
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894383
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.38277
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626616
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.03747
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05473
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.996774
ED-00-OH22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268968
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862441
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219676
XF-42-ES96_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239554
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GF-02-ER50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254046
AA-66-PC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20068
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-84-GJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.635462
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BF-79-GG96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24435
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363389
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.05528
FF-55-AD09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272425
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-13.7802
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2973
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HA-36-VD41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22543
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588696
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
S0-EE-XMWH_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208641
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0897
QE-76-ST29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.429161
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.10224
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16727
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.121
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.882035
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88976
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13576
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263209
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990318
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-493	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-63-XB79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310453
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49362
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.7428
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334493
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-31-GO06_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399807
ND-36-VC68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22251
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08815
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48957
BCP1	CCLE Cell Line Gene CNV Profiles	1.0	1.94196
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029092
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277356
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.13498
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0796
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24863
SB-75-TY18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207188
QE-87-XW53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305353
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TE-26-XS06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337819
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.81539
CC-09-YG11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531995
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8427
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.568974
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.03483
BA-74-WG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246331
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.23639
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.979482
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE122509,GSE122513_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4564
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291659
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42927
CC-70-BD07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452669
AE-05-CB45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.29477
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.59009
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.70473
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30646
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07159
HA-36-VD41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32217
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.31124
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03288
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275875
OF-47-EQ74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206532
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955387
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-42-US78_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.451852
CE-18-CG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311768
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235381
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21005
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.49852
HNF4A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-15-CP52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409625
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.29321
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880685
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-86-IA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210079
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-82-YS26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.614403
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.40829
AA-32-DP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421438
SC-76-YF40_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221711
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570863
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859858
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.22339
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8953
AB-35-RU30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275358
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.14975
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.67425
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903078
S0-EE-Y97N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408061
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.12179
GB-96-WX99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360849
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89699
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431044
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5142
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.93692
TCF12	ENCODE Transcription Factor Targets	1.0	null
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.487066
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EC-86-EK93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.426567
XE-18-BC97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343471
FE-29-XM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316082
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60911
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.54
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203217
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.54506
BC-72-DZ30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230218
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.54102
PMC9229595-Table_2.xlsx-LPS_subset_IX-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916619
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
CE-18-CG29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263506
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23318
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5488
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591387
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91639
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HC-86-IA49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439818
MB-46-BT89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570637
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.5788
AB-12-PP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.505325
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18047
CF-65-GU65_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232837
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258399
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262513
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.88984
XA-82-BM12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286456
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.00989
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5984
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-56-QV45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266336
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3962
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4G_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.992116
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03045
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64375
UE-02-UW61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379159
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-56-JY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257353