association	dataset	threshold value	standardized value
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24086
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1435
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.34615
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9496
organ of corti degeneration	MPO Gene-Phenotype Associations	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.03567
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
Smooth endoplasmic reticulum cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42163
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911122
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375368
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TOM1	Pathway Commons Protein-Protein Interactions	1.0	null
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
FGD4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32787
PITPNA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
decreased circulating potassium level	MPO Gene-Phenotype Associations	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65998
BRD-K52630978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.163
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03898
BRD-K45613561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29715
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.831
limb grasping	IMPC Knockout Mouse Phenotypes	1.0	null
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stereocilia	GeneRIF Biological Term Annotations	1.0	null
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14159
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.132
ED-14-GQ53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266508
sensory perception of light stimulus	GO Biological Process Annotations 2025	1.0	null
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16881
20458058-TableS3b	GeneSigDB Published Gene Signatures	1.0	null
Autosomal recessive nonsyndromic hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
Stereocilia ankle link	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5559
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35118
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
BRD-K02783902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56418
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07848
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56477
BRD-K74705119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08829
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33305
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.43748
CLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597256
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911122
abnormal percent body fat	MPO Gene-Phenotype Associations	1.0	null
EPS8	Pathway Commons Protein-Protein Interactions	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K31354456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3958
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
abnormal inner ear morphology	MPO Gene-Phenotype Associations	1.0	null
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
sensory perception of mechanical stimulus	GO Biological Process Annotations 2023	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neuron projection development	GO Biological Process Annotations 2025	1.0	null
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22657
Lung squamous cell carcinoma_LUSC_TCGA-22-1012-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66855
abnormal locomotor coordination	MPO Gene-Phenotype Associations	1.0	null
hair cell differentiation	GO Biological Process Annotations 2015	1.0	null
BRD-K69437108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34603
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.987
CB-87-RB49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.759486
COS-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955008
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal retina morphology	MPO Gene-Phenotype Associations	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92858
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05858
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.732
Unspecified Visual Loss	DisGeNET Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24734706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43899
Scolopale cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2475
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE70	CCLE Cell Line Gene CNV Profiles	1.0	1.44592
Retinitis pigmentosa	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.61968
T84	CCLE Cell Line Gene Expression Profiles	1.0	1.60145
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04054
pathogenic	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PPP3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00686227
BRD-K99953989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1739
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
small intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Stereocilia ankle link complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.128
GNB1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.786926
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Autoimmune polyendocrine syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9552
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.26947
abnormal eye physiology	MPO Gene-Phenotype Associations	1.0	null
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.938
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02611
MAFK	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43235
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
cytoskeleton	GO Cellular Component Annotations 2015	1.0	null
Perturb_7666_KD_IMP1_DRP003316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.40566
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.516
encoded	GeneRIF Biological Term Annotations	1.0	null
eye	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CYCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00815048
SLC25A37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523678
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42459
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39351
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
BRD-K49328571_dasatinib_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TXLNG	Pathway Commons Protein-Protein Interactions	1.0	null
HGS	Pathway Commons Protein-Protein Interactions	1.0	null
TPX2	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46137
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE216538_1_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35136
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64509
arab	GeneRIF Biological Term Annotations	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
late	GeneRIF Biological Term Annotations	1.0	null
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.551012
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053596
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8176-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outofframe	GeneRIF Biological Term Annotations	1.0	null
MXRA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560356
BRD-K29392278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16767
BRD-K39767907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70102
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Caco-2/BBe cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.598
instability	GeneRIF Biological Term Annotations	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.617982
Congenital diarrhea 5 with tufting enteropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60943
abnormal sensory neuron physiology	MPO Gene-Phenotype Associations	1.0	null
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.08797
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954975
PHARC syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
BRD-K11880555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75617
ENTHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500252
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.401
CDH23	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16800391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0557
NOTCH1_Deficiency_GDS2848_635_mouse_Hair follicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	1.40264
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32386
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00434
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
abnormal colon morphology	MGI Mouse Phenotype Associations 2023	1.0	null
VIPAS39	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831027
abnormal ocular fundus morphology	MPO Gene-Phenotype Associations	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.26947
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
trunk curl	MPO Gene-Phenotype Associations	1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72104
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
photoreceptor outer segment	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938548
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.002
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
FLOT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68192
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03477
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.802
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11107
abnormal hearing electrophysiology	MPO Gene-Phenotype Associations	1.0	null
PXYLP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00469418
quebec	GeneRIF Biological Term Annotations	1.0	null
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02642
SLC25A33	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12072
SW948	GDSC Cell Line Gene Expression Profiles	1.0	2.05043
fruit body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196504
apical part of cell	GO Cellular Component Annotations 2015	1.0	null
PPP1R7	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8398-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08648
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082191
Congenital Sensorineural Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
gastrointestinal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67168
TNFAIP8	Pathway Commons Protein-Protein Interactions	1.0	null
increased bone mineral content	IMPC Knockout Mouse Phenotypes	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536204
TRAPPC3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32091
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26306
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721946
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28365
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955008
Autosomal recessive nonsyndromic deafness 77	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11766
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.52646
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92976
ush	GeneRIF Biological Term Annotations	1.0	null
BRD-K43674766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01851
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral cavernous malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.943
BRD-K77241556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36725
BRD-K86978618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04023
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.27822
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17109
hsa-miR-875-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
regulation of cell projection size	GO Biological Process Annotations 2025	1.0	null
abnormal circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
BLOC1S5	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disequilibrium	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912716
Otosclerosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04353
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Perturb_9752_KO_Rnf20/Rnf40_SRP228497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.81489
cochlear outer hair cell degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02644
cell cycle g2/m phase transition	GO Biological Process Annotations 2015	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PECAPJ49	DepMap CRISPR Gene Dependency	1.0	3.10744
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.871
Usher syndrome type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.382
abnormal retinal pigmentation	HPO Gene-Disease Associations	1.0	null
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.625
SWAP70	Pathway Commons Protein-Protein Interactions	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04256
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.054
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.372366
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0785
Otosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K88385836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10855
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08356
ATG5	Pathway Commons Protein-Protein Interactions	1.0	null
Renal cell carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98015
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864339
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946389
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09201
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.346
betamethasone-dipropionate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70843
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
retinal cone cell differentiation	GO Biological Process Annotations 2023	1.0	null
ZFPL1	Pathway Commons Protein-Protein Interactions	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15038
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55183
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98547
Lung adenocarcinoma_LUAD_TCGA-55-8619-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.39907
SNPH	Pathway Commons Protein-Protein Interactions	1.0	null
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Clumsiness - Motor Delay	DisGeNET Gene-Disease Associations	1.0	null
CLEC12B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00655617
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
GNB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520743
spliced	GeneRIF Biological Term Annotations	1.0	null
PMC9975294-mmc3.xlsx-Silent_TPIT_velocity_genes-gene_TBX19	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29011
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23313
splice	GeneRIF Biological Term Annotations	1.0	null
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_7782_KD_ASCC3_SRP023199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K41327620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87288
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994159
Neuron to neuron synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.617
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15675
BRD-K86606617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02017
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06311
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03662
PSIP1_02_99	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.14839
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46658
Brain Lower Grade Glioma_LGG_TCGA-TM-A84S-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RITA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18887
CCLFPEDS0008T	DepMap CRISPR Gene Dependency	1.0	2.30623
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mitotic cell cycle phase transition	GO Biological Process Annotations 2025	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal energy homeostasis	MPO Gene-Phenotype Associations	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16678
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
MKN74	DepMap CRISPR Gene Dependency	1.0	2.86186
BRD-K16478699_PLX-4720_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FAM21A	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075987
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal inner ear vestibule morphology	MPO Gene-Phenotype Associations	1.0	null
NRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18093
CL34	CCLE Cell Line Gene Expression Profiles	1.0	1.41718
abnormal mechanoreceptor morphology	MPO Gene-Phenotype Associations	1.0	null
Adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormal potassium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3815
BRD-K09106444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32976
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13082
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50416
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09499
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905477
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hallucinations	DisGeNET Gene-Disease Associations	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.50232
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
PFDN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00366435
TREML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599176
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal recessive nonsyndromic deafness 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
hallucinations	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
duodenum	HPA Tissue Gene Expression Profiles	1.0	0.915824
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.063
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25009
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4098
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26797
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076393
BRD-K58138729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0856
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.67911
EC-40-DQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240509
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.56698
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GAA	Pathway Commons Protein-Protein Interactions	1.0	null
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03227
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8863
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840188
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888622
Perturb_7767_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.8786
Lateral wall of outer hair cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00542
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.3324
SW13	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45317
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860134
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10977
BRD-K03995743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29937
inner ear auditory receptor cell differentiation	GO Biological Process Annotations 2025	1.0	null
Autosomal dominant nonsyndromic deafness 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Vestibular Hypofunction	DisGeNET Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
SCP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65637
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89006
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42024
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
FIP1L1_02_147	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.39232
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41185
dimethadione-3367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal stationary movement	MPO Gene-Phenotype Associations	1.0	null
urapidil-3078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
ME-62-IQ37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208573
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.175
Hyperplasia	CTD Gene-Disease Associations	1.0	1.2639
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA3	Pathway Commons Protein-Protein Interactions	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35033
protein localization to microvillus	GO Biological Process Annotations 2025	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2092
GTEX-SE5C-1526-SM-4BRWU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43319
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
central medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.91777
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82958
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87255
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
DCP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53477
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08909
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39501
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
small intestine	HPA Tissue Gene Expression Profiles	1.0	0.930024
GTEX-XUW1-1926-SM-4BOP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35903
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07358
BRD-K54198678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04776
Autosomal dominant nonsyndromic deafness 41	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
abnormal orientation of cochlear hair cell stereociliary bundles	MGI Mouse Phenotype Associations 2023	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08498
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.175
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4786-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80547
ANXA5	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75H-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.933
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40009
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86826
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04467
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.88786
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858945
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.66674
639-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.68556
MMP27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543687
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
consanguineous	GeneRIF Biological Term Annotations	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16879
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11509
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
abnormal physical strength	MPO Gene-Phenotype Associations	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76458
BRD-K93933512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07543
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073575
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19022
GSU	CCLE Cell Line Gene Expression Profiles	1.0	1.62676
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31366
Lung adenocarcinoma_LUAD_TCGA-69-8453-01A-12R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7119
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.33664
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0305
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366754
AA-79-SX47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277059
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.484
mitotic cell cycle phase transition	GO Biological Process Annotations 2023	1.0	null
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.937
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88229
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912298
Eye degenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92949
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_89_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.19222
abnormality of dental structure	HPO Gene-Disease Associations	1.0	null
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942979
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862727
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3729
hair	GeneRIF Biological Term Annotations	1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.919
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19033
abnormal cochlear labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03216
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDKN1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500722
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939868
increased oxygen consumption	MPO Gene-Phenotype Associations	1.0	null
PMC8208823-mmc2.xlsx-CDX2-dataset-feature_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162109
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.395
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79849
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
representing	GeneRIF Biological Term Annotations	1.0	null
RAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Rous sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56795
Stereocilia ankle link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.128
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
childhood	GeneRIF Biological Term Annotations	1.0	null
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9214
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.638
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38078
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.235249
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.48389
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939452
ATP6V1C1	Pathway Commons Protein-Protein Interactions	1.0	null
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
WASF2	Pathway Commons Protein-Protein Interactions	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
myosin heavy chain binding	GO Molecular Function Annotations 2015	1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21253
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW620	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	3.37652
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.596855
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26775
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.370425
MAPKAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94941
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26044
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75756
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1497
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9565
abnormal glucose tolerance	MPO Gene-Phenotype Associations	1.0	null
OSBP	Pathway Commons Protein-Protein Interactions	1.0	null
Autosomal recessive nonsyndromic deafness 39	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.974322
NCIH1930	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92598
STARD5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894294
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.218
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
abnormal neuron physiology	MPO Gene-Phenotype Associations	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06571
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STX12	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Rubella	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
URGCP	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of microvillus length	GO Biological Process Annotations 2023	1.0	null
Perturb_8834_KO_MESP1_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN015_HEPG2_48H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24068
BLOC1S6	Pathway Commons Protein-Protein Interactions	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15826
5q35 copy number variation	WikiPathways Pathways 2024	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855176
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.094
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53248
Microvillar actin bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
VAMP8	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00468
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24197
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163938
relies	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55103
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
BRD-K54785440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40425
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45471
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.32323
SHMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00641257
PPP1R9B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05824
Usher syndrome type 1F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.132
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054429
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.95356
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34215
hsa-miR-1291	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NRAS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1949
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.267505
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220831
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2488
abnormality of the metencephalon	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5027-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Binimetinib_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0257514
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
sans	GeneRIF Biological Term Annotations	1.0	null
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09468
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1485
Spliceosomal tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
HTR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453321
myo7a	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sw-480 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.473092
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59818
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.451
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46512
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85918
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34472
dyskeratosis congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326281
LS-513	GDSC Cell Line Gene Expression Profiles	1.0	1.92483
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02943
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of vision	HPO Gene-Disease Associations	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11272
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.54156
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83563
Leber congenital amaurosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
BRD-K16695519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44443
PCTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497134
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65388
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.128
abnormal hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
stable	GeneRIF Biological Term Annotations	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068469
retinal cone cell development	GO Biological Process Annotations 2025	1.0	null
GIGYF2	Pathway Commons Protein-Protein Interactions	1.0	null
retina	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K67862892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18098
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75403
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.501
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95011
Perturb_5807_OE_MIR192_SRP273723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2512
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
Perturb_12121_KO_Aire_SRP250736	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.6359
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06256
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87978
hearing impairment	HPO Gene-Disease Associations	1.0	null
abnormal adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3809
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870217
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4561
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22466
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05174
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21474
microvillus	GO Cellular Component Annotations 2025	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14951
neuroepithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12836153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48834
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041361
SGK3	Pathway Commons Protein-Protein Interactions	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
hyperactivity	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal circulating potassium level	MPO Gene-Phenotype Associations	1.0	null
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19299
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
night blindness	HPO Gene-Disease Associations	1.0	null
BRD-K03035008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02648
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67355
BRD-K37687095_AZD-8330_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_G007-LK_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141164
USP9X	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32311
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.543
abnormal intestinal epithelium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
atrophy/degeneration affecting the central nervous system	HPO Gene-Disease Associations	1.0	null
head tossing	MGI Mouse Phenotype Associations 2023	1.0	null
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
BRD-K55508908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06502
all	GWASdb SNP-Phenotype Associations	1.0	0.034099
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37039
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal cochlear hair cell inter-stereocilial links morphology	MPO Gene-Phenotype Associations	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2527
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head tossing	MPO Gene-Phenotype Associations	1.0	null
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
Lateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.317
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
top	GeneRIF Biological Term Annotations	1.0	null
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0135
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63467
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.899585
SNX3	Pathway Commons Protein-Protein Interactions	1.0	null
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.917
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.14874
NO11	DepMap CRISPR Gene Dependency	1.0	2.14806
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20403
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919375
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840382
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934283
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11766
11707567-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
BRD-K83690550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51519
abnormal cranial ganglia morphology	MPO Gene-Phenotype Associations	1.0	null
CHARGE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
Lower tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.553
tetraethylenepentamine-406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gallic acid_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0242516
BRD-K77892726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03627
Perturb_5955_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.48604
PRKAR2A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5980_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.54168
BRD-K22874335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16686
Perturb_10326_KO_Shp1_SRP370028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.28981
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071588
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	2.17937
explained	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98547
Alport syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03939
neuron part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00253
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53148
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217299
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.914102
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26204
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920318
brain very small	HPO Gene-Disease Associations	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37603
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41549
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.008
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064203
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890894
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02221
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26782
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21274
VPS4A	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1658
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14795
ANXA11	Pathway Commons Protein-Protein Interactions	1.0	null
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
brush border assembly	GO Biological Process Annotations 2025	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831131
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51701
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264011
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38768
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12613
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.015
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07353
Autosomal recessive nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
BRD-K55623459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0131
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.556685
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04234
decreased circulating glucose level	IMPC Knockout Mouse Phenotypes	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05944
TBC1D4	Pathway Commons Protein-Protein Interactions	1.0	null
Depression	DisGeNET Gene-Disease Associations	1.0	null
Superior semicircular canal dehiscence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12721
BRD-K68595406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08057
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43044
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20978
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.590973
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
USH1G	Pathway Commons Protein-Protein Interactions	1.0	null
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31134
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70027
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal cochlear hair cell stereociliary bundle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K28357534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58872
Stereocilia ankle link complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K56942203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00074
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.039174
BA-86-AL61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.39324
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX2_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
inner ear receptor cell development	GO Biological Process Annotations 2025	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3969
chr11_17524831_T_C_b38	GTEx eQTL 2025	1.0	1.43066
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.30601
RAPGEF4	Pathway Commons Protein-Protein Interactions	1.0	null
ability	GeneRIF Biological Term Annotations	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCFD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98061543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5963
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00480552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20022
actin-based cell projection	GO Cellular Component Annotations 2025	1.0	null
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.064864
TLN2	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02611
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.728908
Retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
ndomain	GeneRIF Biological Term Annotations	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053542
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
deafness	MPO Gene-Phenotype Associations	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20006
KIFC1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22745
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
BRD-K04010869_PROSTAGLANDIN A1_NCIH1694_6.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054328
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23999
RAB10	Pathway Commons Protein-Protein Interactions	1.0	null
RAB18	Pathway Commons Protein-Protein Interactions	1.0	null
TWSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50776
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Myrosin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
Perturb_5385_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16173
BRD-K05804044_AZ-628_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal recessive nonsyndromic deafness 91	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46751
MT1M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456611
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04056
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
recessive	GeneRIF Biological Term Annotations	1.0	null
VPS26A	Pathway Commons Protein-Protein Interactions	1.0	null
ASPC1	CCLE Cell Line Gene Expression Profiles	1.0	1.87178
wortmannin-404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sensory perception of sound	GO Biological Process Annotations 2015	1.0	null
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
Abnormal Vision	DisGeNET Gene-Phenotype Associations	1.0	null
Macular retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17189
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05096
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20711
BICR6	DepMap CRISPR Gene Dependency	1.0	3.51109
sensory perception	GO Biological Process Annotations 2025	1.0	null
decreased triglyceride level	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13879491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09127
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78806
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
MC-CAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0972
DPYD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599134
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1725
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of hindbrain morphology	HPO Gene-Disease Associations	1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
ZFYVE1	Pathway Commons Protein-Protein Interactions	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.88467
Perturb_14552_KO_Abcc8_ERP018163	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
abnormal motor coordination/ balance	MPO Gene-Phenotype Associations	1.0	null
VPS25	Pathway Commons Protein-Protein Interactions	1.0	null
EPHA2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7436
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57245
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.82964
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
organ of Corti degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62336
A549_Aurora A Inhibitor I_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141885
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31366
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CACNG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644265
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33163
aminoacyl-tRNA synthetase multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849261
Ciliopathies	DisGeNET Gene-Disease Associations	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24505
neuron degeneration	MPO Gene-Phenotype Associations	1.0	null
duodenum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K12441550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42415
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1037
PFKFB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00737665
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
formation	GeneRIF Biological Term Annotations	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231875_0_v_1_zbed3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
ZNF384	ENCODE Transcription Factor Targets	1.0	null
utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905404
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.83
ARHGEF10L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09054
Postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
disorders	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2224
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2447
BRD-K62597218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32025
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.67911
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VAMP7	Pathway Commons Protein-Protein Interactions	1.0	null
Usher syndrome type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
BRD-K38131403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.695
Hyperopia	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33204113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57095
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00236
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953335
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
X-linked deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
cochlear inner hair cell degeneration	MPO Gene-Phenotype Associations	1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388158
decreased total body fat amount	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_918_KD_BC200_SRP261125	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4974
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
rather	GeneRIF Biological Term Annotations	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RABEP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
SEC22B	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00547
abamectin-2519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.67911
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87113
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03654
fungus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193642
BRD-K49328571_dasatinib_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87087
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00443
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
Usher syndrome type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
VPS16	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K96510191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36846
abnormal circulating hdl cholesterol level	MPO Gene-Phenotype Associations	1.0	null
Autosomal recessive nonsyndromic deafness 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.844
Autosomal dominant nonsyndromic deafness 65	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.67934
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.62194
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
allele	GeneRIF Biological Term Annotations	1.0	null
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96198
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SW1463	CCLE Cell Line Gene Expression Profiles	1.0	1.38692
Macular holes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912298
protein localization to microvillus	GO Biological Process Annotations 2023	1.0	null
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3383
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.974235
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03939
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26206
cohesion	GeneRIF Biological Term Annotations	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65543
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30711
BRD-K30530468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00199
retinal diseases	GAD Gene-Disease Associations	1.0	null
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57596
Autosomal dominant nonsyndromic deafness 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74774
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
mRNA_AES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RAB17	Pathway Commons Protein-Protein Interactions	1.0	null
atrophy/degeneration affecting the cerebrum	HPO Gene-Disease Associations	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77446
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Postsynaptic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.624
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14617
CD58	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584223
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856287
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74359
impaired swimming	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K77119472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6905
Usher syndrome type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.366
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163729
Macular thickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subcortical Cerebral Atrophy	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55307
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925249
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184414
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
Perturb_6985_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Glesatinib(MGCD265)_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181437
actin filament bundle organization	GO Biological Process Annotations 2025	1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14964
cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29434
nitrendipine-336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal orientation of inner hair cell stereociliary bundles	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97339
QRICH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685533
CD209	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00462272
Perturb_14397_KD_XPR1_SRP347870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.81024
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.245032
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0119
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08628
GTEX-XBED-1526-SM-4AT5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52633
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349442
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04708
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.595
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.764
Autosomal dominant nonsyndromic deafness 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949694
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.03083
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58537
CMPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00388361
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967864
A549	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11796
RIF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90255725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09922
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084468
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
improved glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17083
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22436
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42868
MAPRE1	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
epidermal cell differentiation	GO Biological Process Annotations 2015	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03611
Growth Disorders	CTD Gene-Disease Associations	1.0	1.15763
plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
usher syndrome, type 1c	OMIM Gene-Disease Associations	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58305
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
FAM3C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459696
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.216
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11198
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26806
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94112
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09691
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3306
disease	GWASdb SNP-Disease Associations	1.0	0.031234
GSE264010_0_v_1_parp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
vestibular dysfunction	HPO Gene-Disease Associations	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
18223198-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K35124958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46571
BRD-K56222361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12357
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.139
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	2.61622
BRD-K18004653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62841
Retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2437
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.78534
hsa-miR-2278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF	ENCODE Transcription Factor Targets	1.0	null
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.975
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953664
inner ear receptor cell differentiation	GO Biological Process Annotations 2015	1.0	null
PMC6996670-6370386.f1.xlsx-Supplemental_table_2-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147339
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K95935686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2197
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.617133
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31106
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03589
Adrenocortical carcinoma_ACC_TCGA-OR-A5L8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.787716
BRD-K89550909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27873
STAMBPL1	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67532
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0627
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15251
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7572
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16034
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4158
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47015
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.69616
neuromuscular process controlling balance	GO Biological Process Annotations 2025	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72921
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00655848
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
PRAF2	Pathway Commons Protein-Protein Interactions	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.47012
acadian	GeneRIF Biological Term Annotations	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856287
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.114526
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5677
autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10763
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24263
Fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05302
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	3.38317
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.202006
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32621
POLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68588
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156348
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
structure	GeneRIF Biological Term Annotations	1.0	null
VPS18	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_FOXP1_21924763	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89197
HSG	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
impaired balance	MPO Gene-Phenotype Associations	1.0	null
IQGAP3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10606
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00457
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951928
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
Usher syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.813
PLA2G6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.004895
Perturb_7269_KO_ALKBH3_SRP064738	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49554
PMC9391581-mmc5.xlsx-WT_KLF4_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67379
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06122
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STARD10	Pathway Commons Protein-Protein Interactions	1.0	null
inner ear receptor cell stereocilium organization	GO Biological Process Annotations 2023	1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239366
Hearing impairment	ClinVar Gene-Phenotype Associations 2025	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sub-surface cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074177
NDUFS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453739
BRD-K10493820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36331
developmental process	GO Biological Process Annotations 2015	1.0	null
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.6919
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03977
myc_20940306_e13dot5_erythroblast_purified_from_liver_gof_mouse_gpl6885_gse18558	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.187946
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0517
abnormal orientation of cochlear hair cell stereociliary bundles	MPO Gene-Phenotype Associations	1.0	null
PMC12247205-13046_2025_3465_MOESM1_ESM.xlsx-Table_S4-Table_S4_Upregulated_genes_between_patients_with_high_and_low_ASH1L-AS1_expression_ASH1L	Rummagene Transcription Factor Associations 2026	1.0	null
cell projection	GO Cellular Component Annotations 2015	1.0	null
18786252-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16121
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972142
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anchoring	GeneRIF Biological Term Annotations	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51986
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11295
BRD-A39996500_radicicol_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.52745
OCIM2	DepMap CRISPR Gene Dependency	1.0	3.60101
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32384
increased food intake	IMPC Knockout Mouse Phenotypes	1.0	null
GSE181513_0_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49509
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7638-01B-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K20763958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17943
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397631
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83371
Autosomal recessive nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.3768
OK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
NDUFB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498653
RMND1	Pathway Commons Protein-Protein Interactions	1.0	null
nonsyndromic	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4P3-1226-SM-4AD4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58521
protein binding	GO Molecular Function Annotations 2015	1.0	null
18537972-TableS4	GeneSigDB Published Gene Signatures	1.0	null
STX4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive nonsyndromic deafness 79	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78213
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875752
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51838
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02282
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00914
sporocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28861
VPS28	Pathway Commons Protein-Protein Interactions	1.0	null
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03445
pigmentosa	GeneRIF Biological Term Annotations	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive nonsyndromic deafness 57	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.453
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41182
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09286
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal dominant nonsyndromic deafness 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.184
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.54
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal cochlear outer hair cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.912397
CISD2	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964792
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98547
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
profenamine-3038	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DST	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68635
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	0.863933
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26386
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.538
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03354
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05403
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96515
PDE8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473151
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51685
HS729	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1046
BRD-K50140147_NVP-TAE684_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S16_LF_C2_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1315
hsa-miR-320e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85075
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926434
sensory perception of sound	GO Biological Process Annotations 2025	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67619
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20315
HEPG2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.68922
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58545
Myosin XV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.637
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867083
VPS4B	Pathway Commons Protein-Protein Interactions	1.0	null
sk-n-mc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32497
BRD-K31024887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08063
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.474617
RRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
AsPC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.65259
RALA	Pathway Commons Protein-Protein Interactions	1.0	null
Colonic cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66338
BRD-K14570970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29213
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K59399000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31633
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916047
Actin filament bundle of actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.075
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21588
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906468
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
Retinitis pigmentosa 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Perturb_9022_KD_NR4A2_SRP324495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.3071
E2F1	ChEA Transcription Factor Targets	1.0	null
decreased circulating hdl cholesterol level	MPO Gene-Phenotype Associations	1.0	null
abnormal circulating amylase level	MPO Gene-Phenotype Associations	1.0	null
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75482
PMC4515549-NIHMS63168-supplement-3.xlsx-1B_HNF4A-reg_genes_post-treat-GeneSymbol_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC30A9	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_7869_KD_NEK2_SRP256251	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59241
microvillus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8265
PKN2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881575
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
DMS-114	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stereocilium bundle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48564
lisinopril-5504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26871
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2162
Liver Diseases	CTD Gene-Disease Associations	1.0	1.03715
PRXL2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559697
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891974
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
eye photoreceptor cell development	GO Biological Process Annotations 2025	1.0	null
Upper tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.245
BRD-K68149575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54514
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917311
STX18	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58225
SiHa	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53436
levallorphan-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23478
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
Perturb_743_KD_RASSF2_SRP233387	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08909
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0972
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961064
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16767
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67811
Perturb_6335_KO_MLL4SET_SRP221512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6248
GSE132948,GSE132949_4_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal body fat mass	MPO Gene-Phenotype Associations	1.0	null
BRD-K39101193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66003
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35921
abnormal glucose homeostasis	MPO Gene-Phenotype Associations	1.0	null
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
CHMP1B	Pathway Commons Protein-Protein Interactions	1.0	null
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41625
Myosin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
CL14	CCLE Cell Line Gene Expression Profiles	1.0	3.40784
ACOT11	Pathway Commons Protein-Protein Interactions	1.0	null
vestibular hair cell degeneration	MPO Gene-Phenotype Associations	1.0	null
Autosomal recessive nonsyndromic deafness 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.789
tip	GeneRIF Biological Term Annotations	1.0	null
BRD-K09203354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82884
abnormal circulating lipoprotein level	MPO Gene-Phenotype Associations	1.0	null
BRD-K98384558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05423
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85734
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88536
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19543
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78684
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Baraitser-Winter syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_downregulated_in_the_low_MEIS1_content_thalamus_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.926637
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35177
VMRCRCW	CCLE Cell Line Gene Expression Profiles	1.0	1.41661
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849984
Blue color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285507
SNX5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the retinal pigment epithelium	HPO Gene-Disease Associations	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3852
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.2821
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pendred Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.334
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
decreased circulating amylase level	MPO Gene-Phenotype Associations	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13663
BRD-K62182950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18703
GSE232261,GSE232263_0_v_1_usf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16115
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	3.26152
ERGIC1	Pathway Commons Protein-Protein Interactions	1.0	null
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
ABCC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517022
Amniotic cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	2.17855
abnormal cochlear hair bundle tip links morphology	MPO Gene-Phenotype Associations	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.132
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9686
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
impaired righting response	MPO Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958857
Perturb_275_KD_USP13_SRP343502	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K01077691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74266
cell cycle G2/M phase transition	GO Biological Process Annotations 2025	1.0	null
SACM1L	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6892
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.21875
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938021
ECSIT	Pathway Commons Protein-Protein Interactions	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2759
sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K53772256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16486
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26662
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nyctalopia	DisGeNET Gene-Disease Associations	1.0	null
Motor Delay	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56871
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053455
esrra_19901197_kidney_lof_mouse_gpl1261_gse16623	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.171877
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.216
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Ciliary landscape	WikiPathways Pathways 2024	1.0	null
GLYR1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25203
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08598
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90791
Perturb_9004_KD_C19orf12_SRP212737	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
increased bone mineral content	MPO Gene-Phenotype Associations	1.0	null
Myosin III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.528
TCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595728
BRD-K95033255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37973
Perturb_17570_KD_Tead4_SRP089678	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50505
origin	GeneRIF Biological Term Annotations	1.0	null
Cavernous hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
BRD-K39328339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95231
CCDC121	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472265
Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33153
Perturb_5904_KD_EBNA1BP2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.96939
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
ACVR2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00691156
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32251
BRD-K23535862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03927
RGCC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00429531
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43033
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.629
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
increased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.5238
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.88125
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83462
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913529
abnormal pinna reflex	MPO Gene-Phenotype Associations	1.0	null
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56871
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7872
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19888
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25036
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18013
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955008
CACYBP	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8357_KO_DAPK1_SRP356770	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.57155
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19592
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47772
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49313
Renal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
multivalent	GeneRIF Biological Term Annotations	1.0	null
PHYH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00415367
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87373
Perturb_9024_KD_NR4A2_SRP324495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.7667
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11902
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.89925
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.853
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFATC3_01_166	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61016
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8669
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23382
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.75947
increased or absent threshold for auditory brainstem response	MPO Gene-Phenotype Associations	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07265
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888644
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH292	CCLE Cell Line Gene CNV Profiles	1.0	1.47867
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
autosomal	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901366
BAZ1A	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5806_KO_GPR31_SRP117665	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
link	GeneRIF Biological Term Annotations	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46658
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
AA-32-DP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.24547
protein-containing complex organization	GO Biological Process Annotations 2025	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microvillus	GO Cellular Component Annotations 2015	1.0	null
SMAD4	Pathway Commons Protein-Protein Interactions	1.0	null
PLEK2	Pathway Commons Protein-Protein Interactions	1.0	null
DPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510581
BRD-K76694128_DCC-2036_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BET1	Pathway Commons Protein-Protein Interactions	1.0	null
COG4	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49001
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.127
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
SCH	DepMap CRISPR Gene Dependency	1.0	8.38331
BCL11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515179
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mucolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
A549_PFI-1_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126554
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	1.778
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.809
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97370549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38453
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945389
absent pinna reflex	MPO Gene-Phenotype Associations	1.0	null
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989778
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinitis pigmentosa 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.056796
BRD-K57084585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28337
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	9.58854
AOC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00729637
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70721
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35589
methylbenzethonium chloride-3768	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49671
pimasertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1471
blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.12572
GZMM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615138
BRD-K53396471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44517
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
TM9SF1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73321
DIDO1	Pathway Commons Protein-Protein Interactions	1.0	null
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
GALE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503974
Kinesin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
STAG1	Pathway Commons Protein-Protein Interactions	1.0	null
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
CXCL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544009
SHF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589291
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell morphogenesis involved in neuron differentiation	GO Biological Process Annotations 2025	1.0	null
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12022
Candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.294053
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ADAM10	Pathway Commons Protein-Protein Interactions	1.0	null
Photoreceptor cell cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-A06158172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32661
RDH13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467757
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.13562
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal circulating lipid level	MPO Gene-Phenotype Associations	1.0	null
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85796
SNU423	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49083
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053911
H3118	DepMap CRISPR Gene Dependency	1.0	15.4265
abnormal hair cell mechanoelectric transduction	MGI Mouse Phenotype Associations 2023	1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
cilium	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.38737
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE252857_2_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978015
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.265
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H630	GDSC Cell Line Gene Expression Profiles	1.0	1.92003
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.454
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.56667
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57121
Perturb_10436_KD_SKA3_SRP188124	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE138815,GSE138817_3_v_1_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00683912
COLO679	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43075
protein-containing complex organization	GO Biological Process Annotations 2023	1.0	null
exons	GeneRIF Biological Term Annotations	1.0	null
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09298
ACAP2	Pathway Commons Protein-Protein Interactions	1.0	null
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.8
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9614
cause	GeneRIF Biological Term Annotations	1.0	null
USE1	Pathway Commons Protein-Protein Interactions	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.1552
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65388
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
BCAP29	Pathway Commons Protein-Protein Interactions	1.0	null
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939145
BRD-K48046422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12879
bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173015
visual impairment	HPO Gene-Disease Associations	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal hair cell physiology	MPO Gene-Phenotype Associations	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5983_KD_YBX3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.1942
Leber congenital amaurosis with early-onset deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
149br	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
abnormal sensory ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NECTIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00771174
hypermetropia	HPO Gene-Disease Associations	1.0	null
BRD-K54332480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06929
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03248
CDK5	Pathway Commons Protein-Protein Interactions	1.0	null
RIPK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578582
RAP2B	Pathway Commons Protein-Protein Interactions	1.0	null
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of microvillus organization	GO Biological Process Annotations 2023	1.0	null
C84	DepMap CRISPR Gene Dependency	1.0	6.52097
CRCGN015_HEPG2_48H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21342
ensure	GeneRIF Biological Term Annotations	1.0	null
Autosomal recessive nonsyndromic deafness 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49204
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42863
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	1.0	3.13702
Actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.185
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25426
JAK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81385845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66356
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53394
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14541
neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179765
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06166
BRD-K82968105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09505
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.679025
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829172
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.53965
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TNFSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571597
population	GeneRIF Biological Term Annotations	1.0	null
horsetail-astral microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2597
bundle	GeneRIF Biological Term Annotations	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cystoid macular edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
RAB3GAP1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.742
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.9107
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13433
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30927
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	1.44335
Rectum adenocarcinoma_READ_TCGA-AF-4110-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07887
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990191
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26073
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.235249
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0197
Polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13073
CRCGN015_MCF10A.TP53.M_24H:J11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08605
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06537
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44037
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.27845
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.447
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83277
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6056
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ATXN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557545
Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34989
deferoxamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88591
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
Electroretinogram	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal enzyme/ coenzyme level	MPO Gene-Phenotype Associations	1.0	null
Peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23299
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.21
decreased circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86183
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13082
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.438739
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.363766
BRD-K99755021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45155
Sensory processing of sound by outer hair cells of the cochlea	Reactome Pathways 2024	1.0	null
absent pinna reflex	IMPC Knockout Mouse Phenotypes	1.0	null
regulation of cell projection size	GO Biological Process Annotations 2023	1.0	null
FRMPD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7488531-13287_2020_1914_MOESM10_ESM.xlsx-HNF4A_regulated_DEGs_750-Unnamed_1_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
stereocilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
cytosol	GO Cellular Component Annotations 2015	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03391
hsa-miR-193a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992108
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal cochlear outer hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
colonic cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal bone structure	MPO Gene-Phenotype Associations	1.0	null
prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.98669
chr11_17515292_C_T_b38	GTEx eQTL 2025	1.0	4.82073
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25828
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38351
BRD-K71590663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00384
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30895
nonmotile primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
RSF1	Pathway Commons Protein-Protein Interactions	1.0	null
DBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34007
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1519
BRD-K36812047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17293
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Athabaskan brainstem dysgenesis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23411
alternatively	GeneRIF Biological Term Annotations	1.0	null
Auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PPP5C	Pathway Commons Protein-Protein Interactions	1.0	null
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38481
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14361
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.08
deafness	GeneRIF Biological Term Annotations	1.0	null
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.15296
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Harmonin	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0873
RAB43	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pirenperone-3316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18119
EPS8L3	Pathway Commons Protein-Protein Interactions	1.0	null
COG3	Pathway Commons Protein-Protein Interactions	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47772
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
actin filament bundle organization	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38521
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26023
Autosomal recessive nonsyndromic deafness 74	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4925
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.198
actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.565923
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.757258
Retinal Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
ARL2	Pathway Commons Protein-Protein Interactions	1.0	null
increased lean body mass	IMPC Knockout Mouse Phenotypes	1.0	null
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
impaired righting response	MGI Mouse Phenotype Associations 2023	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57089
GSE162276_4_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	2.18444
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5712
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29345
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.565
BRD-K07591425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41075
DEAFNESS, AUTOSOMAL RECESSIVE 18A	CTD Gene-Disease Associations	1.0	2.88009
BRD-K08504955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19509
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23591737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11547
SAP30	ENCODE Transcription Factor Targets	1.0	null
inner ear morphogenesis	GO Biological Process Annotations 2023	1.0	null
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
circling	MGI Mouse Phenotype Associations 2023	1.0	null
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stereocilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
PDHB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436326
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05078
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.47283
Autosomal recessive nonsyndromic deafness 33	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
abnormal gas homeostasis	MPO Gene-Phenotype Associations	1.0	null
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.538
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
eye photoreceptor cell development	GO Biological Process Annotations 2023	1.0	null
BRD-K75152103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44917
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased circulating sodium level	MGI Mouse Phenotype Associations 2023	1.0	null
Abnormalities, Multiple	HuGE Navigator Gene-Phenotype Associations	1.0	null
Norrie disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
linkage	GeneRIF Biological Term Annotations	1.0	null
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
decreased sterol level	MPO Gene-Phenotype Associations	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
IPCEF1	Pathway Commons Protein-Protein Interactions	1.0	null
PHA-00851261E-3968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Autosomal dominant nonsyndromic deafness 27	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04987
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052312
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970333
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2594
MOSPD2	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05849
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74798
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863824
RAB33B	Pathway Commons Protein-Protein Interactions	1.0	null
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
BRD-K75177817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03678
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
sirolimus-2681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.8459
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75674
cellular_component	GO Cellular Component Annotations 2015	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66891
RCOR1	ENCODE Transcription Factor Targets	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858945
Neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.536
i10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079526
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Sensorineural Hearing Loss, Bilateral	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.046227
BRD-K95147502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47945
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.40857
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02706
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.134
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9565_KO_Cdx2_SRP149724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.8238
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00712
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1511
cerebral cortical atrophy	HPO Gene-Disease Associations	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984793
Pigmentary Iris Degeneration	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K58534531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28152
LMCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580138
congenital	GeneRIF Biological Term Annotations	1.0	null
decreased circulating amylase level	IMPC Knockout Mouse Phenotypes	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
mechanoreceptor differentiation	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX4	Pathway Commons Protein-Protein Interactions	1.0	null
NC-73-QU79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205439
SAGA-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3204
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04255
abnormal eye morphology	MPO Gene-Phenotype Associations	1.0	null
RUFY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481351
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myosin I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25747
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13082
MAPK8IP3	Pathway Commons Protein-Protein Interactions	1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326281
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08961
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04818
abnormal circulating triglyceride level	MPO Gene-Phenotype Associations	1.0	null
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19101
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72192
Rectum adenocarcinoma_READ_TCGA-F5-6813-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.909666
Human - Motor Cortex - Cross-Species Cluster - oligodendrocyte_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49574
cell cycle G2/M phase transition	GO Biological Process Annotations 2023	1.0	null
Y-linked deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.999
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.654
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
LAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25194
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6857
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67848
9+0 non-motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
Cone dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.146
fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091541
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.432
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065166
Retinal Toxicity	DisGeNET Gene-Disease Associations	1.0	null
stereotypic behavior	IMPC Knockout Mouse Phenotypes	1.0	null
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.946
Hyperinsulinemic hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55074
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857601
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.930414
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76307
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.16047
BRD-K65147077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81936
STEAP3	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1G1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX3	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal inner hair cell stereociliary bundle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241469
Perturb_6331_KO_Gaa_SRP042287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.72437
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943675
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
families	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8618
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13187
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55845
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36587
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21569
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44378
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888472
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4726-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
shown	GeneRIF Biological Term Annotations	1.0	null
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42415
SEPT8	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11031166-SAG-2302-87_0_Appendix_1_SG_IHDS_(569_genes)_Final_List.xlsx-AP1-Genes_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
zalcitabine-4215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10593
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1794
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10706
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal cholesterol homeostasis	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13282
bephenium hydroxynaphthoate-5628	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21494
abnormal inner hair cell stereociliary bundle morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68988
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
auditory receptor cell differentiation	GO Biological Process Annotations 2015	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.103
RAB14	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14685
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50191
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.596855
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81897
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_S3I-201_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157671
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43262
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084613
Perturb_7129_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
RAN	Pathway Commons Protein-Protein Interactions	1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08993
ZWINT	Pathway Commons Protein-Protein Interactions	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.97378
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
epithelial cell differentiation	GO Biological Process Annotations 2015	1.0	null
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27369
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
eltanolone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22374
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061836
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05325
Perturb_417_OE_PINK1_SRP327521	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.82877
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21884
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF888	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57715
BRD-K57080016_-666_HT29_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCT116	DepMap CRISPR Gene Dependency	1.0	5.89007
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57195030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19499
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11213
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
Perichromatin fibrils	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
Apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL6IP1	Pathway Commons Protein-Protein Interactions	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03191
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12121
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.367
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19448
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.83
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CNPY3	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal grip strength	MPO Gene-Phenotype Associations	1.0	null
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
deafness-dystonia-optic neuronopathy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
highlight	GeneRIF Biological Term Annotations	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MTOR_UP.N4.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
Senescence_frontal cortex_GSE1572	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.65188
BRD-K41645779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32203
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.957
BRD-K46824282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35047
SW1116	GDSC Cell Line Gene Expression Profiles	1.0	1.64522
Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934376
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-25-VR48_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258973
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSK3A_KD_GDS4305_180_human_MOLM-14 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51577639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12314
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.344831
ticlopidine-4074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K48019220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37974
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36414
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912298
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992925
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal somatic sensory system morphology	MPO Gene-Phenotype Associations	1.0	null
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSBPL10	Pathway Commons Protein-Protein Interactions	1.0	null
hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692085
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNX13	Pathway Commons Protein-Protein Interactions	1.0	null
retinal cone cell differentiation	GO Biological Process Annotations 2025	1.0	null
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3692
BRD-K00615600_AG14361_SW480_6.0_h_25.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.67
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
sensory perception of mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11726
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11437
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.43
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1040	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38971
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
STXBP3	Pathway Commons Protein-Protein Interactions	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069232
DGKK	Pathway Commons Protein-Protein Interactions	1.0	null
spanish	GeneRIF Biological Term Annotations	1.0	null
equilibrioception	GO Biological Process Annotations 2025	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46448
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857601
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093759
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845643
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87025
deafness	MGI Mouse Phenotype Associations 2023	1.0	null
epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K01297681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32048
PMC5094973-oncotarget-07-35932-s004.xlsx-c2_cp_biocarta_v4_0_symbols-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.3922
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
increased fluid intake	MPO Gene-Phenotype Associations	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52144
Perturb_3944_KD_BRD4_SRP063978	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
absent pinna reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PRKD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574388
destabilize	GeneRIF Biological Term Annotations	1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BE-71-AV63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369403
BUB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00656945
X-linked juvenile retinoschisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916644
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01959
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914194
molecular_function	GO Molecular Function Annotations 2015	1.0	null
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57765
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
actin filament bundle assembly	GO Biological Process Annotations 2023	1.0	null
usher	GeneRIF Biological Term Annotations	1.0	null
abnormal carbon dioxide production	MPO Gene-Phenotype Associations	1.0	null
improved glucose tolerance	MPO Gene-Phenotype Associations	1.0	null
interactions	GeneRIF Biological Term Annotations	1.0	null
SULT2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514071
CDH23-harmonin transmembrane complex	CORUM Protein Complexes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43285
Perturb_5334_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.74341
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26351
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.88
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9943
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.111511
KIF4A	Pathway Commons Protein-Protein Interactions	1.0	null
SNU81	CCLE Cell Line Gene Expression Profiles	1.0	1.63352
HCFC1	Pathway Commons Protein-Protein Interactions	1.0	null
RALB	Pathway Commons Protein-Protein Interactions	1.0	null
GRIPAP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
neurodegeneration	MPO Gene-Phenotype Associations	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6046
abnormal electroretinogram	HPO Gene-Disease Associations	1.0	null
BRD-K89515752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73719
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.152699
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.56964
regulation of microvillus length	GO Biological Process Annotations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EB-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248668_1_v_0_atxn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal hearing physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K38904629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17518
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17083
actin filament bundle organization	GO Biological Process Annotations 2023	1.0	null
A704	GDSC Cell Line Gene Expression Profiles	1.0	1.45383
localized	GeneRIF Biological Term Annotations	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.032218
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
internal	GeneRIF Biological Term Annotations	1.0	null
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998339
Photoreceptor inner segment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.027769
inner ear morphogenesis	GO Biological Process Annotations 2015	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1653
A549_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128912
primary cilium	GO Cellular Component Annotations 2015	1.0	null
Perturb_7071_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.10494
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03498
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7117
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304092
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34961
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62502
Hemianopsia	DisGeNET Gene-Disease Associations	1.0	null
stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.01052
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
UCHL3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911122
auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925068
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2924
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11246
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96701
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837119
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
epithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31877
GSE161027,GSE161028_1_v_3_foxo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.7
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980921
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.19414
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.53508
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	2.25532
immunohistochemistry	GeneRIF Biological Term Annotations	1.0	null
all	HPO Gene-Disease Associations	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-2026-SM-4KL1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37603
Nonsyndromic Deafness	DisGeNET Gene-Disease Associations	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88536
Nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Perturb_727_OE_QKI5_SRP293637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Usher syndrome type 1G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.606
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62885
loss	GeneRIF Biological Term Annotations	1.0	null
NDNL2	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64418254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11513
essential	GeneRIF Biological Term Annotations	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2346
RINT1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10605_KO_Abcc9_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.36509
photoreceptor inner segment	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
differentiate	GeneRIF Biological Term Annotations	1.0	null
Extrinsic component of external side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
STAMBPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520103
Achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05657
PTP4A1	Pathway Commons Protein-Protein Interactions	1.0	null
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.174
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69969
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal fluid intake	MPO Gene-Phenotype Associations	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28496
GOSR1	Pathway Commons Protein-Protein Interactions	1.0	null
ARF4	Pathway Commons Protein-Protein Interactions	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24192
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38552
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838431
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.991
inner ear receptor cell differentiation	GO Biological Process Annotations 2023	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83563
inner ear auditory receptor cell differentiation	GO Biological Process Annotations 2023	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.4813
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13925
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
SMEK1	Pathway Commons Protein-Protein Interactions	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.071432
VTI1A	Pathway Commons Protein-Protein Interactions	1.0	null
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
usher syndrome	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38726
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
Leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
BRD-K80381603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02593
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.67911
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44378
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12184916_-666_CL34_6.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	2.27192
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.66149
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
actin-based cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44973
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04443
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear ganglion degeneration	MPO Gene-Phenotype Associations	1.0	null
STX17	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49901
SCARB2	Pathway Commons Protein-Protein Interactions	1.0	null
SEPT10	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_02_185	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.678
hsa-miR-1208	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04692
DOCK6	Pathway Commons Protein-Protein Interactions	1.0	null
cellular component assembly	GO Biological Process Annotations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.575393
ARHGAP27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555028
CHMP1A	Pathway Commons Protein-Protein Interactions	1.0	null
A549_SL-327_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131924
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24197
endocrine pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.118746
description	GeneRIF Biological Term Annotations	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2379
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S12_LF_C1_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
photoreceptor inner segment	GO Cellular Component Annotations 2015	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.984608
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.085565
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.432
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.63366
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
Branchiootorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
increased red blood cell distribution width	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K53893978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35622
trunk curl	IMPC Knockout Mouse Phenotypes	1.0	null
BC-22-OI74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236031
PMC3500769-srep00875-s3.xls-GATA3-Time_4_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200214_0_v_2_mrgpra1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01378
RAB35	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K10011427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39152
active	GeneRIF Biological Term Annotations	1.0	null
BRD-K06226868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81775
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21039
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_7086_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.07646
markers	GeneRIF Biological Term Annotations	1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
abnormality of dental enamel	HPO Gene-Disease Associations	1.0	null
PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
PITPNB	Pathway Commons Protein-Protein Interactions	1.0	null
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	0.929727
Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942087
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49334
retinitis	GeneRIF Biological Term Annotations	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867379
Autosomal dominant auditory neuropathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
Necrosis	CTD Gene-Disease Associations	1.0	1.22016
HOOK1	Pathway Commons Protein-Protein Interactions	1.0	null
C2CD4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571617
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
abnormal circulating mineral level	MPO Gene-Phenotype Associations	1.0	null
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3839
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.861054
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.205
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
Arciform density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.604
decreased body size	MPO Gene-Phenotype Associations	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
TRAPPC4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13572
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37774987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15194
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98547
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34394
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31483
KSR2_knockout_60_GSE17923	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.33624
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86352
TJP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal dominant nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
FBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477911
m cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.465335
GTEX-XYKS-2226-SM-4E3IU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37477
sector	GeneRIF Biological Term Annotations	1.0	null
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.281
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.195
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067109
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77696
SEC31A	Pathway Commons Protein-Protein Interactions	1.0	null
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	1.36023
retinitis pigmentosa	HPO Gene-Disease Associations	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.43771
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38627
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0889
photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.465198
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06315
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.77026
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
Hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19724
LS-1034	GDSC Cell Line Gene Expression Profiles	1.0	2.03868
chr11_17533369_C_A_b38	GTEx eQTL 2025	1.0	2.07527
A549_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130666
NCI-SNU-5	GDSC Cell Line Gene Expression Profiles	1.0	1.50911
PLEKHF2	Pathway Commons Protein-Protein Interactions	1.0	null
decreased grip strength	MPO Gene-Phenotype Associations	1.0	null
BRD-K36737730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28466
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K63960902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09765
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tbl1x	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12561
PMC11950762-BLOODA_ADV-2024-014354-mmc2.pdf-24-TCFL5_TCFL5	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5387_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.92956
TAF15_02_106	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
P2RX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608352
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46736
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19583
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076909
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23262
HS695T	DepMap CRISPR Gene Dependency	1.0	4.51307
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16925
Autosomal recessive nonsyndromic deafness 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02471
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.4186
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15763
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.35498
Autosomal recessive nonsyndromic deafness 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
Stereocilium tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.87
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08248
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76788397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2252
abnormal organ of corti morphology	MPO Gene-Phenotype Associations	1.0	null
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08738
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EIF2D	Pathway Commons Protein-Protein Interactions	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04091
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
R3HDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00895344
Idioblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01956
PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal cone dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
EXOC8	Pathway Commons Protein-Protein Interactions	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54638
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB5C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K69291887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77455
sensory perception of mechanical stimulus	GO Biological Process Annotations 2025	1.0	null
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.541
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47038
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.605
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48167
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.811
shaping	GeneRIF Biological Term Annotations	1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99258
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3525_KD_NDP52_SRP345438	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
myosin tail binding	GO Molecular Function Annotations 2015	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04209
HOP-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93036
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32657
Electroretinogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
cochlear hair cell degeneration	MPO Gene-Phenotype Associations	1.0	null
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65077
IQGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K93993174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32294
Acoustic neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
interleukin-2 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049191
GSE165307_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36554
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93833
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.52616
abnormality of the head	HPO Gene-Disease Associations	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101656
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
Tympanum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.379
vestibular hypofunction	HPO Gene-Disease Associations	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08367
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3977
Autosomal recessive nonsyndromic deafness 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2309
abnormal cochlear hair cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.299
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
ATP6V1C2	Pathway Commons Protein-Protein Interactions	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14006
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.838469
Rectum adenocarcinoma_READ_TCGA-EI-6514-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040795
BRD-K66655211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42274
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61958
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02149
Autosomal recessive nonsyndromic deafness 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.881
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26219
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872849
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49224
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83185
BRD-K51398207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3862
Autosomal recessive nonsyndromic deafness 63	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59044
MFE296	DepMap CRISPR Gene Dependency	1.0	2.01791
CRCGN016_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01974
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887837
GBF1	Pathway Commons Protein-Protein Interactions	1.0	null
increased lean body mass	MPO Gene-Phenotype Associations	1.0	null
BAZ1B	Pathway Commons Protein-Protein Interactions	1.0	null
increased circulating sodium level	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31749
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.734
CACNB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573206
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5176-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34406
phenotype	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased bone mineral content	MGI Mouse Phenotype Associations 2023	1.0	null
floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00528558
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.585
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42977
abnormal protein level	MPO Gene-Phenotype Associations	1.0	null
BRD-K83189379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14483
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24098
VAV2	Pathway Commons Protein-Protein Interactions	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7446
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03729
abnormal orientation of inner hair cell stereociliary bundles	MPO Gene-Phenotype Associations	1.0	null
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073857
BRD-K64417176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24398
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98547
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW1417	GDSC Cell Line Gene Expression Profiles	1.0	2.65371
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05566
Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98378
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04812
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
CL40	CCLE Cell Line Gene Expression Profiles	1.0	1.9788
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60255
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45607
NB-1691 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
abnormal sodium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
QKI	Pathway Commons Protein-Protein Interactions	1.0	null
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
theophylline-3326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.94997
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979612
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
BRD-K20061970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49227
CNN2	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68635
hearing	GeneRIF Biological Term Annotations	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874486
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.394
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.164
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53346
HCV JFH-1_12Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60233
berry	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366754
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal dominant nonsyndromic deafness 3B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
TPRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83407
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048474
BRD-K93578426_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106116
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471539
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8485
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08277
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00976
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal chloride level	MPO Gene-Phenotype Associations	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32466
CARMIL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00449337
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25568
decreased small intestinal microvillus size	MGI Mouse Phenotype Associations 2023	1.0	null
Retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15982
BRD-K59606563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29402
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51512
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23885
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22174
ASPSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-3.18599
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31252
mitotic cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
NAPG	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein-containing complex assembly	GO Biological Process Annotations 2023	1.0	null
hsa-miR-3126-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WASL	Pathway Commons Protein-Protein Interactions	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26466
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.20127
MYO7A	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18013
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68418
SW1463	GDSC Cell Line Gene Expression Profiles	1.0	1.73989
BHY	CCLE Cell Line Gene CNV Profiles	1.0	1.41785
BRD-K91799761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78832
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5731
MAZ	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.801
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03276
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.855281
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13234
causes	GeneRIF Biological Term Annotations	1.0	null
increased circulating chloride level	MPO Gene-Phenotype Associations	1.0	null
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
impaired balance	MGI Mouse Phenotype Associations 2023	1.0	null
DNMBP	Pathway Commons Protein-Protein Interactions	1.0	null
TGM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00524736
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870597
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XC-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10804
AA-22-UI44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298755
neuromuscular process controlling balance	GO Biological Process Annotations 2023	1.0	null
fragment	GeneRIF Biological Term Annotations	1.0	null
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cochlear inner hair cell degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.015
Entorhinal area, medial part, dorsal zone, layer 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36145
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4521181-oncsis201520x8.pdf-10-ARHGAP35_ARHGAP35	Rummagene Transcription Factor Associations 2026	1.0	null
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.466
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
increased circulating sodium level	MPO Gene-Phenotype Associations	1.0	null
MTOR	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
digitoxigenin-4217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040202
BRD-K34977825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28142
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264696
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968946
SEL1L	Pathway Commons Protein-Protein Interactions	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.365
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.661523
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062499
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
kidney cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HSF1_KD_GDS1733_756_human_HeLa cells -  2 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
abnormal sensory neuron morphology	MPO Gene-Phenotype Associations	1.0	null
ART3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607404
BRD-K27121064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39656
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05523
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29578
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07044
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6265
Perturb_7896_KO_NEURL4_SRP336645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.60509
neurological system process	GO Biological Process Annotations 2015	1.0	null
abnormal skin adnexa morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K98704738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27025
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V0D1	Pathway Commons Protein-Protein Interactions	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
villin	GeneRIF Biological Term Annotations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643163
Scotoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08598
Perturb_6704_KD_LPA2_SRP057199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.95413
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pallister-Hall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21534
abnormal circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
Excretory canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61534
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50539
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06698399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46503
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal circulating chloride level	MPO Gene-Phenotype Associations	1.0	null
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34861
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
oxprenolol-3568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86831676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4276
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70006
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22662
PMC4060771-170289.f1.pdf-677-ASCL2_ASCL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.476
Usher syndrome type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.698
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54936
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.815
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.255
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.809
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968284
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84969
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02209
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40024
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.504
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.5138
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43106305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21026
Perturb_5332_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77408
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.467
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30703
stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.0055
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57784
LMO7	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341126
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tegmental area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860397
embryonic morphogenesis	GO Biological Process Annotations 2015	1.0	null
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0988
WF-85-JN16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210339
BRD-K54123736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11156
tilmicosin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5025
onset	GeneRIF Biological Term Annotations	1.0	null
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09163
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anchorage	GeneRIF Biological Term Annotations	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49477
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
formed	GeneRIF Biological Term Annotations	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP1G1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_6984_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8578
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41532
EIF2B5	Pathway Commons Protein-Protein Interactions	1.0	null
PLEKHH1	Pathway Commons Protein-Protein Interactions	1.0	null
AKT1S1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71731
Developmental and epileptic encephalopathy 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal hair follicle morphology	MPO Gene-Phenotype Associations	1.0	null
PMC10070455-41598_2023_32568_MOESM3_ESM.xlsx-Genes_AA-genes_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97615
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42136
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06938
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89565
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.748
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12122
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955008
BRD-K03188480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18402
sensory perception of light stimulus	GO Biological Process Annotations 2015	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07651
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175675
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6906
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912045
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393064
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55O-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCAL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00434451
SOX9	ChEA Transcription Factor Targets	1.0	null
decreased circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13292
BRD-K67905771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62645
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14431
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	3.10125
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27653
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0247
BRD-K50434315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07473
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3358
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14307
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1749
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26167
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
BRD-K79781106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08021
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
JURKAT	DepMap CRISPR Gene Dependency	1.0	3.1286
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Perturb_753_KD_ABAT_SRP385901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.336
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
photoreceptor cell maintenance	GO Biological Process Annotations 2015	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K98135954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04447
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927118
Accessory outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.443
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61318
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4003
Autosomal recessive nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
AA-76-VE74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375564
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0909
BRD-K41809155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08269
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97204
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19118372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60487
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08431
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01898
founder	GeneRIF Biological Term Annotations	1.0	null
Endoplasmic reticulum cisternal network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
abnormal circulating protein level	MPO Gene-Phenotype Associations	1.0	null
sensitive	GeneRIF Biological Term Annotations	1.0	null
DMS-273	COSMIC Cell Line Gene Mutation Profiles	1.0	null
four	GeneRIF Biological Term Annotations	1.0	null
Perturb_9611_KO_Sufu/Spop_SRP117241	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.66922
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8914
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
POR_KO_GDS1678_763_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02929
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.67926
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18611
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal small intestine morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.356
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.867
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42596
GSE136311_1_v_0_lyz2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280364
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49816
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250301
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4683
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01046
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.985692
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05834
increased circulating chloride level	IMPC Knockout Mouse Phenotypes	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.673
viia	GeneRIF Biological Term Annotations	1.0	null
Perrault syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
A549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Ground meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44171
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02406
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072815
Usher syndrome, type 1C	ClinVar Gene-Phenotype Associations	1.0	null
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00883
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K0-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24627
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07923
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380627
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60056
TCCPAN2	CCLE Cell Line Gene Expression Profiles	1.0	1.61016
PMC10350897-j_biol-2022-0528-S1.pdf-181-USF2_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20962
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7492_KD_TAF6_SRP174861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ELMO3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29339
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53274
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
SHB	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42024
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT55	GDSC Cell Line Gene Expression Profiles	1.0	1.88928
CJM	CCLE Cell Line Gene CNV Profiles	1.0	1.41451
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23827
BRD-K10435664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99777
BRD-K44866331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38378
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB21	Pathway Commons Protein-Protein Interactions	1.0	null
type	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88045
Usher syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.792
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.04705
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHMP2A	Pathway Commons Protein-Protein Interactions	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09584
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
BRD-K51370144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76109
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TICAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.008494
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0133
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
RP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00425871
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.319
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67151
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60999
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03212
EZH2	ENCODE Transcription Factor Targets	1.0	null
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.988
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Insulin-Dependent Diabetes Mellitus Secretory Diarrhea Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Perturb_529_KO_NFE2L1_SRP333364	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.80077
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
KMOE-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95127
LRCH4	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSK3B_knockdown_209_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.38327
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7668_KD_IMP3_DRP003316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.90988
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19449
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7L_KO_GDS2857_556_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS29	Pathway Commons Protein-Protein Interactions	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.953664
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55311
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868877
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40611
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.915
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	1.0	null
cefixime-4390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
recombination	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53154
SYNE2	Pathway Commons Protein-Protein Interactions	1.0	null
Cell body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.3593
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15281
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74265
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26889
abnormal cholesterol level	MPO Gene-Phenotype Associations	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59046641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08179
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18787
abnormal cochlear hair bundle tip links morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SCAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
SI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536201
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Duodenum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66305
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
ear morphogenesis	GO Biological Process Annotations 2025	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69771
CPNE3	Pathway Commons Protein-Protein Interactions	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.12
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68956
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13382
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
abnormal mineral homeostasis	MPO Gene-Phenotype Associations	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
Gyrate atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.594753
inner ear receptor cell development	GO Biological Process Annotations 2023	1.0	null
SCN1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519315
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.942
DCTN3	Pathway Commons Protein-Protein Interactions	1.0	null
GCIY	CCLE Cell Line Gene Expression Profiles	1.0	1.69174
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.09461
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33588
ARL8A	Pathway Commons Protein-Protein Interactions	1.0	null
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.779
RABL6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAB19	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858945
HS294T	DepMap CRISPR Gene Dependency	1.0	2.30025
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06224
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.228108
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.05738
Methotrexate	CTD Gene-Chemical Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96442
cochlear ganglion degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
abnormal scala media morphology	MPO Gene-Phenotype Associations	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02035
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088005
FNDC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00562109
myosin binding	GO Molecular Function Annotations 2015	1.0	null
A1CF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461696
CD177	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556397
Perturb_10305_KO_Cxcl12_SRP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.00352
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	4.24313
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
hsa-miR-556-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
LB373-MEL-D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABRA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511121
Kinociliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060196
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.07025
CRCGN010_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12235
GSE162276_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40347
head bobbing	MGI Mouse Phenotype Associations 2023	1.0	null
GABBR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004934
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82903
Perturb_7868_KD_NEK2_SRP256251	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.5696
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14996
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06803
villi	GeneRIF Biological Term Annotations	1.0	null
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23542
CE-36-KR60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292607
FAR/SIN/STRIPAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.508242
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
Retinitis pigmentosa	ClinVar Gene-Phenotype Associations 2025	1.0	null
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78174
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
KU812	DepMap CRISPR Gene Dependency	1.0	2.10384
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05716
inner ear receptor cell stereocilium organization	GO Biological Process Annotations 2025	1.0	null
PTSD - Post-traumatic stress disorder_Peripheral blood mononuclear cell_GSE860	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.21441
Apical proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K49207204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96576
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08113
BRD-K49328571_dasatinib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188804
BRD-K44494409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12115
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00832
PLEKHA2	Pathway Commons Protein-Protein Interactions	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03775
neuron part	GO Cellular Component Annotations 2015	1.0	null
retina degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
BRD-K77875023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15351
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2637
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00331016
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
FNBP1L	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864364
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3475
Perturb_14555_KO_ELF3_SRP051606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.38282
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17955_KO_Snca_SRP377748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57216
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
Autosomal recessive nonsyndromic deafness 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.033
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67585
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Protein body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VPS37B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914763
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04596
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846811
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-1326-SM-4LVMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41758
Photoreceptor outer segment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1124
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive nonsyndromic deafness 102	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4813
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43865
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42905
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912298
A549_BMS-536924_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200865
G2/M transition of mitotic cell cycle	GO Biological Process Annotations 2023	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866582
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11583
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
EIF2B3	Pathway Commons Protein-Protein Interactions	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.490944
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6
BRD-K20285085_R406_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37328
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
actin filament organization	GO Biological Process Annotations 2015	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53342
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064203
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04897
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
A549_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0084752
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.749
A549_FLLL32_10µM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012011
BRD-K36232701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17068
GDI2	Pathway Commons Protein-Protein Interactions	1.0	null
UHRF1	Pathway Commons Protein-Protein Interactions	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
ABR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17850764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23034
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0874
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043272
regulation of microvillus organization	GO Biological Process Annotations 2025	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
inner ear receptor cell differentiation	GO Biological Process Annotations 2025	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
Perturb_279_KD_MBNL2_SRP077885	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.80206
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
abnormal electroretinogram waveform feature	MPO Gene-Phenotype Associations	1.0	null
Blindness	DisGeNET Gene-Phenotype Associations	1.0	null
18277965-Table4b	GeneSigDB Published Gene Signatures	1.0	null
Perturb_14502_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.92806
Hypolemmal cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
BRD-K51454545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03496
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 33	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
CHP1	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866054
Autoimmune polyendocrine syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40304
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07383
Cochlear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
SAAL1	Pathway Commons Protein-Protein Interactions	1.0	null
ALOX15B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436953
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.7324
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59327
known	GeneRIF Biological Term Annotations	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840188
equilibrioception	GO Biological Process Annotations 2015	1.0	null
GTEX-XUJ4-1226-SM-4BOPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917425
ANKRD11	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00784535
Human - Motor Cortex - Cluster - OPALIN+ ENPP6+ Layer 3-6 oligodendrocyte	HuBMAP Azimuth Cell Type Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67031
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
PMC11960529-mmc4.xlsx-Atrial_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26298
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26898
Absent Vestibular Function	DisGeNET Gene-Phenotype Associations	1.0	null
brush border assembly	GO Biological Process Annotations 2023	1.0	null
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K42650945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13127
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10647
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00367
abnormal cochlear inner hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.067
LPS6	DepMap CRISPR Gene Dependency	1.0	2.08499
canadian	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81093
structures	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81261
Usher syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9523
CRCGN008_HEPG2_24H:I09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01655
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840188
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58758
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.288
MDAMB361	DepMap CRISPR Gene Dependency	1.0	7.19911
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17040651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87615
BRD-K49328571_dasatinib_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07884
EPS8L2	Pathway Commons Protein-Protein Interactions	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957519
BRD-K48583488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10706
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1644
flunisolide-3923	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARAP1	Pathway Commons Protein-Protein Interactions	1.0	null
TMCO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695453
NUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79997
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.5231
PLEKHG3	Pathway Commons Protein-Protein Interactions	1.0	null
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.992
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043627
TAP2	Pathway Commons Protein-Protein Interactions	1.0	null
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
BRD-K49345010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03686
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042345
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
abnormal auditory brainstem response	MPO Gene-Phenotype Associations	1.0	null
Autosomal dominant nonsyndromic deafness 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
LMTK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481693
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03345
GTEX-S7SF-0626-SM-4AD4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885701
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
CYB5D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747859
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.37
Perturb_16720_Mut_Lmna_SRP309326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.61317
Autosomal dominant nonsyndromic deafness 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61056
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.9667
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45972
abnormality of the face	HPO Gene-Disease Associations	1.0	null
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31567
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Deafness	DisGeNET Gene-Disease Associations	1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Usher syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
RTP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501892
auditory receptor cell morphogenesis	GO Biological Process Annotations 2025	1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15908
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04588
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.774
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CCDC50	Pathway Commons Protein-Protein Interactions	1.0	null
A-Netherlands-602-2009(H1N1)_30Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.08322
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
usher syndromes	GAD Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17924
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.610778
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164092
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52489
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34131
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GSE132948,GSE132949_4_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54518
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09337
KIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.84987
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07914
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00631
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52712
CENPV	Pathway Commons Protein-Protein Interactions	1.0	null
induce	GeneRIF Biological Term Annotations	1.0	null
BRD-K08811598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30644
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75803
cdx2_21074721_jejunum_epithelium_lof_mouse_gpl10773_gse23436	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.566852
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911122
protein localization	GO Biological Process Annotations 2025	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30472
composed	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVJ-1326-SM-48U1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25337
Fatty Liver	CTD Gene-Disease Associations	1.0	1.23265
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66F-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17192395-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0465
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06738
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17013
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
PIK3C2B	Pathway Commons Protein-Protein Interactions	1.0	null
Orofaciodigital syndrome I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24113
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10072
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53952
Small intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHMP5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56384677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13534
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16611
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8759
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10807
abnormal somatic nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29642
vestibular hair cell degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.30143
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11279
GCIY	GDSC Cell Line Gene Expression Profiles	1.0	1.51122
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837422
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	1.45757
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05352
detailed	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32765
PMC5481429-41598_2017_4370_MOESM2_ESM.xls-SOM-cluster-genes_transcriptionally_related_to_DNAJC22_in_human_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44068
spectrin binding	GO Molecular Function Annotations 2015	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
synapse	GO Cellular Component Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48946
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64804596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28216
visual field defect	HPO Gene-Disease Associations	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31332
Autosomal recessive nonsyndromic deafness 35	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109574
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
CSNK1A1	Pathway Commons Protein-Protein Interactions	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245175
HCC38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
site	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15363
PMC7388612-vdaa078_suppl_supplementary_table_6.xlsx-MRs_PN_Rim-vs-MRs_PN_C-MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BLTP3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550461
YE-55-YX75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259512
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
been	GeneRIF Biological Term Annotations	1.0	null
DJM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93317
BRD-A18328003_GDC-0980_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PUS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00803356
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3323
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26044
VAPA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
G2/M transition of mitotic cell cycle	GO Biological Process Annotations 2025	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
GSE89569_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02394
BRD-K08831772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.142
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
abnormal mineral level	MPO Gene-Phenotype Associations	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4479
abnormal electroretinogram waveform feature	MGI Mouse Phenotype Associations 2023	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.819616
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3899
BRD-K14756138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98618
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47216
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7864-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
india	GeneRIF Biological Term Annotations	1.0	null
BRD-K47348275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5195
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.859
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77301
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06368
Perturb_7125_KO_Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.54086
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal circulating sodium level	MPO Gene-Phenotype Associations	1.0	null
CATSPER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00700515
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital Deafness	DisGeNET Gene-Disease Associations	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11247
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.11809
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919375
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32765
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
spectrum	GeneRIF Biological Term Annotations	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56665
nicotine_mus musculus_gpl1261_gse31004	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.742
BRD-K26214026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27387
COLO201	CCLE Cell Line Gene Expression Profiles	1.0	1.69517
actin filament bundle assembly	GO Biological Process Annotations 2015	1.0	null
BRD-K86448296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1513
abnormal outer hair cell stereociliary bundle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76494
circling	MPO Gene-Phenotype Associations	1.0	null
BRD-K90852412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51236
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42428
Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940391
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95674
FCER2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505514
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
GABRD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515385
ULK3	Pathway Commons Protein-Protein Interactions	1.0	null
congenital sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31106
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323509
metamizole sodium-6030	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SDK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057367
abnormal membranous labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
mediate	GeneRIF Biological Term Annotations	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
ER body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0565
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02512
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56609
chaperones modulate interferon signaling pathway	Biocarta Pathways	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05821
COMMD3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11979
GTPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532491
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.92632
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11415
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16298
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37929
MAFF	ENCODE Transcription Factor Targets	1.0	null
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82517
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97564
Carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56871
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16478
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946604
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844343
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28982
abnormal hair cell mechanoelectric transduction	MPO Gene-Phenotype Associations	1.0	null
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43955
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985554
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-43-CV47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223747
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
BRD-K47895166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05864
first	GeneRIF Biological Term Annotations	1.0	null
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48343
Autosomal recessive nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
MAP4K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486677
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208044
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59798
stereocilium bundle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886896
Autosomal dominant nonsyndromic deafness 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.201
outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19445
SGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499887
BRD-K13265046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33833
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66669
Usher syndrome type 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.093
BRD-K73475697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19921
LGR5	Pathway Commons Protein-Protein Interactions	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
AP1M2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
Apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.257
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68635
MYOF	Pathway Commons Protein-Protein Interactions	1.0	null
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
NUP50	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
meclocycline-6637	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
A549_UNC1999_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153952
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74258
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48222
Brain Lower Grade Glioma_LGG_TCGA-HW-7495-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76633
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29711
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1594
g2/m transition of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
cataract	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17176016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66518
protein-containing complex assembly	GO Biological Process Annotations 2025	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00383
Autosomal recessive nonsyndromic deafness 49	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05352
BRD-K95479169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4657
RAB6A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12049
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42024
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14988
KYSE-70	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52898
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928664
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943346
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
Autosomal recessive nonsyndromic deafness 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.154
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919508
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
TEC	Pathway Commons Protein-Protein Interactions	1.0	null
IFNAR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00345184
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888638
EIF2B2	Pathway Commons Protein-Protein Interactions	1.0	null
CCND1	Pathway Commons Protein-Protein Interactions	1.0	null
17210682-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
EW-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
RB1_KD_GSE50532_659_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K01639343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2939
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
STX5	Pathway Commons Protein-Protein Interactions	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3023
ZW10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181492_1_v_0_chrysin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
large	GeneRIF Biological Term Annotations	1.0	null
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
altered righting response	MPO Gene-Phenotype Associations	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888903
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR61	Pathway Commons Protein-Protein Interactions	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.6479
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.80819
Brush border	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05194
Perturb_5939_KD_NONO_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.5855
abnormal posture	MPO Gene-Phenotype Associations	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19262
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
GOSR2	Pathway Commons Protein-Protein Interactions	1.0	null
CW-2	GDSC Cell Line Gene Expression Profiles	1.0	1.63356
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67546
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08932
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00125
early	GeneRIF Biological Term Annotations	1.0	null
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.966995
GOLT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24781
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0224
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFATC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41194
A549_ZM 447439_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149713
KDM5B	ENCODE Transcription Factor Targets	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6507
parallel actin filament bundle assembly	GO Biological Process Annotations 2023	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38584
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79893
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
alone	GeneRIF Biological Term Annotations	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04068
RHEB	Pathway Commons Protein-Protein Interactions	1.0	null
stem	GeneRIF Biological Term Annotations	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8099
Autoimmune Enteropathy	DisGeNET Gene-Disease Associations	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09093
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12862
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1379
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12135
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45758
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
Autosomal dominant nonsyndromic deafness 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
PRR14L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
VAC14	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92524632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35407
RFX5	ENCODE Transcription Factor Targets	1.0	null
SNAP23	Pathway Commons Protein-Protein Interactions	1.0	null
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077687
BRD-K77345736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81402
Box H/ACA scaRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36612
RAP1GDS1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852285
SEPT14	Pathway Commons Protein-Protein Interactions	1.0	null
equilibrioception	GO Biological Process Annotations 2023	1.0	null
GOLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3670	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01975
report	GeneRIF Biological Term Annotations	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.01652
Filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.329
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86134
Perturb_3846_KD_CABLES2_SRP166266	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.75552
placental	GeneRIF Biological Term Annotations	1.0	null
increased red blood cell distribution width	IMPC Knockout Mouse Phenotypes	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.07418
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal dominant nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
PMC3500769-srep00875-s3.xls-AP1-Time_4_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.7428
DLX5_Deficiency_GDS4443_355_mouse_E10 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
actin binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876623
vision	GAD High Level Gene-Disease Associations	1.0	0.300704
BRD-K01749472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9315
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.926
HCV JFH-1_18Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.27899
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
brush border	GO Cellular Component Annotations 2015	1.0	null
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30892
Cerebrocostomandibular syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05549
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TJP1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9405
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8611
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.595599
Epithelioma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
U-87-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN008_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63383
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16148
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.039349
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04866
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gata-4_KO_GDS4782_329_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2023	1.0	null
abnormal cochlea morphology	MPO Gene-Phenotype Associations	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.976241
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RABAC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-2026-SM-3LK5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20379
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11079511-ir-2023-00162-Supplementary-Table-1.pdf-3-LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
neuroepithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183682
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
GSE227592_0_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.906995
PRKAG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614767
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32904
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44024
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.6919
NCI H322M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02824
CDK4	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal lipoprotein level	MPO Gene-Phenotype Associations	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34552
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987784
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66801
BRD-K34106082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1849
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5295
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35689168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23048
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076172
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991847
ANKS4B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BD-49-MD69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238085
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.61441
PPM1A	Pathway Commons Protein-Protein Interactions	1.0	null
nfe2l2_00000000_neonate_p3_lung_lof_mouse_gpl1261_gse29632	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.466307
decreased total body fat amount	MPO Gene-Phenotype Associations	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78511
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09885
ATP9A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00621596
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8197
SW948	CCLE Cell Line Gene Expression Profiles	1.0	2.1557
KDM4A	ENCODE Transcription Factor Targets	1.0	null
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14738
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857684
BRD-K32035967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21505
PDCD4	Pathway Commons Protein-Protein Interactions	1.0	null
usher syndrome	GAD Gene-Disease Associations	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62063
BRD-K13697445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39874
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00547
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.00863
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.933
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CAB39	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
contractile	GeneRIF Biological Term Annotations	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
NUP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22491
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1956
USHBP1	Pathway Commons Protein-Protein Interactions	1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
colon	GTEx Tissue Gene Expression Profiles	1.0	1.17772
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K11990377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31578
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23077
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24843
increased energy expenditure	MPO Gene-Phenotype Associations	1.0	null
NCIH684	CCLE Cell Line Gene Expression Profiles	1.0	1.6914
PDE3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647896
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.975
CRCGN015_HEPG2_48H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58148
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.381969
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08616
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95461
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.803
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.871
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3976
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3058
amniotic cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604099
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
RASL11A	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Marshall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
mitotic cell cycle process	GO Biological Process Annotations 2015	1.0	null
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52809
LCLC-97TM1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53672
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13956
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2109
photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.511233
ANXA9	Pathway Commons Protein-Protein Interactions	1.0	null
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19555
enteropathy	GeneRIF Biological Term Annotations	1.0	null
neuron differentiation	GO Biological Process Annotations 2015	1.0	null
bardet-biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.556732
apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27927
autoantibodies	GeneRIF Biological Term Annotations	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72685
Actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.181
atropine methonitrate-6495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PTGIS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758075
amnion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15203
BRD-K30962012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43592
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K75637705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23624
Perturb_276_KD_USP13_SRP343502	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.65513
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064801
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997649
Autosomal recessive nonsyndromic deafness 48	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
Cluster of actin-based cell projections	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
abnormal orientation of outer hair cell stereociliary bundles	MPO Gene-Phenotype Associations	1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11817
SYNJ2BP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25509
uncovered	GeneRIF Biological Term Annotations	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K44946060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06655
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0967
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05849
Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78234
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.996
Perturb_15323_KD_PLIN2_SRP380168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.14879
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37649
PTK2	Pathway Commons Protein-Protein Interactions	1.0	null
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
impaired righting response	IMPC Knockout Mouse Phenotypes	1.0	null
Autosomal recessive nonsyndromic deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.938
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
LS-513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LRP10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29338816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28159
Usher syndrome type 1E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.223
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15465
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.435775
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
decreased circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
abnormal triglyceride level	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K42465630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74265
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.07742
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11891
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56545
Perturb_7124_KO_Prkcd/Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13052
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78297
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40148
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
GUCY1A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658763
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.822
ZNF143	ENCODE Transcription Factor Targets	1.0	null
xp17pv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
atypical	GeneRIF Biological Term Annotations	1.0	null
targeted	GeneRIF Biological Term Annotations	1.0	null
abnormal cochlear ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-1203	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
sensory perception of sound	GO Biological Process Annotations 2023	1.0	null
RTN3	Pathway Commons Protein-Protein Interactions	1.0	null
Abnormal Cochlea Morphology	DisGeNET Gene-Disease Associations	1.0	null
hair cell differentiation	GO Biological Process Annotations 2023	1.0	null
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.28253
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.936845
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain atrophy	HPO Gene-Disease Associations	1.0	null
EA-40-GQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244701
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC2998	GDSC Cell Line Gene Expression Profiles	1.0	1.61718
hair cell differentiation	GO Biological Process Annotations 2025	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0711
BRD-K98529522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20527
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09575
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63476
P31-FUJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84405
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.942
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02011
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5197
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880757
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960911
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.355
impaired hearing	MPO Gene-Phenotype Associations	1.0	null
halcinonide-7379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TFAP2A	ChEA Transcription Factor Targets	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53BP2	Pathway Commons Protein-Protein Interactions	1.0	null
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.7527
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02199
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.61974
chlorpropamide-3210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.846175
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.33962
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065639
stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.0109
SFT2D3	Pathway Commons Protein-Protein Interactions	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.213
S117	DepMap CRISPR Gene Dependency	1.0	2.63111
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31329
nonmotile primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.727941
DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Usher Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39717
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B_knockdown_158_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.38327
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21798
abnormal ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
Allpo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
Stereocilia tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.187
decreased circulating triglyceride level	MPO Gene-Phenotype Associations	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.43834
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7217064-IJC-146-3354-s005.xlsx-Table_S6-Supplementary_Table_S6_Genes_significantly_upregulated_in_OC2-transfected_MKN74_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57304
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.198
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94403
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67175
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12778
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
Chronic mucocutaneous candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
AMME complex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.935
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.39013
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8991
BRD-K60144139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01956
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OPTN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484373
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74148
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977074
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43992612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30096
Spinalcord	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79566
myosin	GeneRIF Biological Term Annotations	1.0	null
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
impaired swimming	MPO Gene-Phenotype Associations	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8994
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66301
parallel actin filament bundle assembly	GO Biological Process Annotations 2015	1.0	null
KIF2A	Pathway Commons Protein-Protein Interactions	1.0	null
decreased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
Brain Lower Grade Glioma_LGG_TCGA-FG-8185-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50140257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21608
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053049
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891153
ARL1	Pathway Commons Protein-Protein Interactions	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65064082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13168
SNX1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18821
ARHGAP8	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
DGKQ	Pathway Commons Protein-Protein Interactions	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409351
Rare genetic deafness	ClinVar Gene-Phenotype Associations 2025	1.0	null
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17246
cadherin23	GeneRIF Biological Term Annotations	1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066798
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASAH1	Pathway Commons Protein-Protein Interactions	1.0	null
Stereocilium tip	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cochlear labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
abnormal ear physiology	MPO Gene-Phenotype Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22793
assemblies	GeneRIF Biological Term Annotations	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17199
Benign paroxysmal positional vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38344
RAB9A	Pathway Commons Protein-Protein Interactions	1.0	null
Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
cell cycle process	GO Biological Process Annotations 2015	1.0	null
MAPK7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC22A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00468348
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
limb grasping	MGI Mouse Phenotype Associations 2023	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37635
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21057
Gastrointestinal cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autosomal recessive nonsyndromic deafness 31	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
PHF8	ENCODE Transcription Factor Targets	1.0	null
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06727
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15617
SIGMAR1	Pathway Commons Protein-Protein Interactions	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16023
GNB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00471054
Autosomal dominant nonsyndromic deafness 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41362
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
late-onset retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
MHH-CALL-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5594
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00669
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28169
sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.58359
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08847
actin filament bundle assembly	GO Biological Process Annotations 2025	1.0	null
PMC7272325-41436_2020_759_MOESM2_ESM.xlsx-Table_S4-single_AR_alleles-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EXOC6	Pathway Commons Protein-Protein Interactions	1.0	null
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26204
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.84813
Hypertrophy	CTD Gene-Disease Associations	1.0	1.10527
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13234
cilium	GO Cellular Component Annotations 2023	1.0	null
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18172
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51336
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22087
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990262
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.41184
SEC31B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48609
Immunodeficiency 41	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50631
increased circulating chloride level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840188
LGALS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00351502
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_728_OE_QKI5_SRP293637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
actin-based cell projection	GO Cellular Component Annotations 2023	1.0	null
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.369
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40886
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27123
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56568
HLA-C	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.53052
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30801
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7694
cognitive impairment	HPO Gene-Disease Associations	1.0	null
Autosomal dominant nonsyndromic deafness 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Autosomal recessive nonsyndromic deafness 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.584
Baraitser-Winter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
actin filament binding	GO Molecular Function Annotations 2015	1.0	null
SPECC1L	Pathway Commons Protein-Protein Interactions	1.0	null
PIN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16588281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05435
Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
SNX14	Pathway Commons Protein-Protein Interactions	1.0	null
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.781
BRD-K55679243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05823
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845545
BL70	DepMap CRISPR Gene Dependency	1.0	2.39918
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
repair	GeneRIF Biological Term Annotations	1.0	null
High vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
BRD-K42435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6439
BRD-K97223487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00167
abnormal cochlear sensory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BIN1	Pathway Commons Protein-Protein Interactions	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2478
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90385
CRCGN015_MCF10A_48H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14257
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
S 1 (combination)	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormal enterocyte morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.619
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6326
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57344
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.06402
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.207
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09362
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40513181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62642
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3312
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OF-37-IT01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302887
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971512
Aplasia/Hypoplasia Of The Cerebellum	DisGeNET Gene-Phenotype Associations	1.0	null
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20454
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.717
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.556685
decreased percent body fat	MPO Gene-Phenotype Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
effect	GeneRIF Biological Term Annotations	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04068
abnormal energy expenditure	MPO Gene-Phenotype Associations	1.0	null
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
abnormal head movements	MPO Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954404
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.057
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03391
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Scotoma	DisGeNET Gene-Phenotype Associations	1.0	null
Sensory processing of sound	Reactome Pathways 2024	1.0	null
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.242
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61418
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20252
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.0621
rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50272743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.94457
Autosomal recessive nonsyndromic deafness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
OE19	CCLE Cell Line Gene Expression Profiles	1.0	1.72478
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972675
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20046
EIF2B4	Pathway Commons Protein-Protein Interactions	1.0	null
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17357
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953849
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
nonmotile primary cilium	GO Cellular Component Annotations 2015	1.0	null
SNU-C1	GDSC Cell Line Gene Expression Profiles	1.0	1.68163
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65752
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
DUSP3	Pathway Commons Protein-Protein Interactions	1.0	null
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12466
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648938
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89418
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876466
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062628
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00806
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12306
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80198
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.14336
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
Factor VII deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04297
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10336
abnormal cochlear hair cell stereociliary bundle morphology	MPO Gene-Phenotype Associations	1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.30259
RAB2A	Pathway Commons Protein-Protein Interactions	1.0	null
incoordination	HPO Gene-Disease Associations	1.0	null
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52654
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906373
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02111
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
deafness, autosomal recessive 18a	OMIM Gene-Disease Associations	1.0	null
neuron projection development	GO Biological Process Annotations 2023	1.0	null
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
Stereocilium shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.69
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.668933
Perturb_5915_KD_HNRNPA2B1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.87879
abnormal drinking behavior	MPO Gene-Phenotype Associations	1.0	null
pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	3.10125
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49213
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.586
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.189
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17951
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34013
Perturb_5914_KD_HMGA1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.68999
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
SMAD2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27680690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16097
cerebral atrophy	HPO Gene-Disease Associations	1.0	null
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K10775155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59667
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIVF001-006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3067
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.55024
ush1g	GeneRIF Biological Term Annotations	1.0	null
Perturb_2805_KD_TINCR_SRP180203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
cilium	GO Cellular Component Annotations 2025	1.0	null
BRD-K93109423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30599
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40403
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74153
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3776
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16386
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular hemostatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8165
Perturb_15411_KD_GATA2_SRP043960	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.88314
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29396
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.58167
EP300	ChEA Transcription Factor Targets	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05849
Autosomal recessive nonsyndromic deafness 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34766
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal circulating enzyme level	MPO Gene-Phenotype Associations	1.0	null
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47383
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930497
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91793
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.68319
GTEX-SNOS-0826-SM-4DM5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878514
BRD-K65005311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25474
TRIM24	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	2.1819
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17923
stereotypic behavior	MPO Gene-Phenotype Associations	1.0	null
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07349
microvillus	GO Cellular Component Annotations 2023	1.0	null
BRD-K20203758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2802
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05966
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_02_60	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.36786
Autosomal recessive nonsyndromic deafness 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
BRD-K22481359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73886
adipose tissue phenotype	MPO Gene-Phenotype Associations	1.0	null
increased carbon dioxide production	MPO Gene-Phenotype Associations	1.0	null
increased food intake	MGI Mouse Phenotype Associations 2023	1.0	null
Autosomal recessive nonsyndromic deafness 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
BRD-K04695993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40047
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04879
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45769
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0721
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K84688359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54075
AB-82-EP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.427971
Autosomal recessive nonsyndromic deafness 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
A549_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140146
BRD-K56729241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27197
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1588	CCLE Cell Line Gene Expression Profiles	1.0	1.90511
BCCIP	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal oxygen consumption	MPO Gene-Phenotype Associations	1.0	null
Perturb_14699_KO_TET1_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.36035
PMC12123029-41598_2025_3625_MOESM1_ESM.pdf-30-NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.225
homologous	GeneRIF Biological Term Annotations	1.0	null
cases	GeneRIF Biological Term Annotations	1.0	null
abnormal cochlear hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
head bobbing	MPO Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996492
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
within	GeneRIF Biological Term Annotations	1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.829084
Leber congenital amaurosis 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03208
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K71758378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42742
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45646
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.317
harmonin	GeneRIF Biological Term Annotations	1.0	null
filamentous actin	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.4672
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory processing of sound by inner hair cells of the cochlea	Reactome Pathways 2024	1.0	null
abnormal postural reflex	MPO Gene-Phenotype Associations	1.0	null
ARHGAP35	Pathway Commons Protein-Protein Interactions	1.0	null
cadherin	GeneRIF Biological Term Annotations	1.0	null
BRD-K67998155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26736
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289358
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.45075
retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
RABL3	Pathway Commons Protein-Protein Interactions	1.0	null
TFRC	Pathway Commons Protein-Protein Interactions	1.0	null
Microvillus inclusion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Enlarged vestibular aqueduct	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.178
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0117
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26466
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDCD6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13873561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34485
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cnidoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
Autosomal dominant nonsyndromic deafness 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915121
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062837
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
PPP2R5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534514
X-linked nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07603
BRD-K70397964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21741
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85873301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65967
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53911
Asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.621
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40798
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79275
MYO7B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850845
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
MD-17-VD78_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312216
renal cell carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972821
EIF2B1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26488
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
SLC19A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536311
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64414
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39146
Perturb_7024_Mut_Htt_SRP043967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73329
PKN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472977
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_JQ1_1µM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112456
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10616
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
CRCGN010_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01149
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46944
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.11
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11239
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66565
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37401
BRD-K90660470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49503
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31357
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral Cortical Atrophy	DisGeNET Gene-Disease Associations	1.0	null
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.78205
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
hsa-miR-142-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60595
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10031
stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.950189
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
abnormal posterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26306
CADPS2	Pathway Commons Protein-Protein Interactions	1.0	null
AVPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00631694
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48782
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.21219
GSE140965_2_v_3_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Choanal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
X-linked deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
Perturb_3838_KO_ITPR3_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.19417
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GNAI1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
TNFRSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607338
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08139
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185313
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23256
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception	GO Biological Process Annotations 2023	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trunk curl	MGI Mouse Phenotype Associations 2023	1.0	null
israeli	GeneRIF Biological Term Annotations	1.0	null
Congenital diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04231
Usher syndrome, type 1C	CTD Gene-Disease Associations	1.0	2.88009
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.4609
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955008
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SLC38A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578757
MAD1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.616
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
gentamycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35282
sensorineural	GeneRIF Biological Term Annotations	1.0	null
BRD-K78965436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43019
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Usher syndrome type 3B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.447
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.252
Goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
Usher syndrome type 1J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
DC-08-KP05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248832
Nematocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02318
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
SKP1	Pathway Commons Protein-Protein Interactions	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55844
abnormal bone mineral content	MPO Gene-Phenotype Associations	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.01663
CPNE1	Pathway Commons Protein-Protein Interactions	1.0	null
tonzonium bromide-4617	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33789
actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.481661
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.555559
BRD-K36909552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14924
hsa-miR-4454	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34557
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
unit	GeneRIF Biological Term Annotations	1.0	null
STX16	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal orientation of outer hair cell stereociliary bundles	MGI Mouse Phenotype Associations 2023	1.0	null
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
CRCGN010_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15559
TBP	ENCODE Transcription Factor Targets	1.0	null
DOORS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30389
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ush1	GeneRIF Biological Term Annotations	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Y-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
PLA2G4B	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188570,GSE188571_5_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.543
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43317
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85521
Perturb_7658_KD_CTCF_SRP128556	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
abnormality of coordination	HPO Gene-Disease Associations	1.0	null
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50023
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2822
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Deafness, autosomal recessive 18	ClinVar Gene-Phenotype Associations	1.0	null
West Nile encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78518
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3976
Otitis media	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.178
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
peptide	GeneRIF Biological Term Annotations	1.0	null
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
CORL279	DepMap CRISPR Gene Dependency	1.0	3.50304
MEFV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681126
PDZ domain	InterPro Predicted Protein Domain Annotations	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046268
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
vascular disease	GWASdb SNP-Disease Associations	1.0	0.079955
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nematocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.218
abnormal lean body mass	MPO Gene-Phenotype Associations	1.0	null
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97279
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE252857_2_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stereotypic behavior	MGI Mouse Phenotype Associations 2023	1.0	null
decreased circulating amylase level	MGI Mouse Phenotype Associations 2023	1.0	null
parallel actin filament bundle assembly	GO Biological Process Annotations 2025	1.0	null
french	GeneRIF Biological Term Annotations	1.0	null
Jalili syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.908785
Autosomal recessive nonsyndromic deafness 27	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
photoreceptor outer segment	GO Cellular Component Annotations 2015	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70794
MERO14	DepMap CRISPR Gene Dependency	1.0	2.68326
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26306
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.242
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80865
RAB23	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13258_KO_Pcgf3/Pcgf5_SRP115638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.39703
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909667
Parallel actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.965
RHOA	Pathway Commons Protein-Protein Interactions	1.0	null
Cataract	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
idazoxan-6465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855767
hsa-miR-4640-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HD-29-PZ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236096
GOLPH3	Pathway Commons Protein-Protein Interactions	1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.034
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8326_KD_HOTAIR_SRP105050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.78509
abnormal cochlear hair cell inter-stereocilial links morphology	MGI Mouse Phenotype Associations 2023	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20077
STAM	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99357
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S01_LF_C1_3h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
RAB11B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.887727
clemastine-2412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5278-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10046096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05002
retinal cone cell development	GO Biological Process Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
improved glucose tolerance	IMPC Knockout Mouse Phenotypes	1.0	null
PHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20979
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61256
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05765
GSE224237_1_v_2_resiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ush1c	GeneRIF Biological Term Annotations	1.0	null
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040592
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09484
dementia	GWASdb SNP-Disease Associations	1.0	0.340336
UNC93B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6290-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNF8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner ear morphogenesis	GO Biological Process Annotations 2025	1.0	null
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
abnormal vestibular hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K36716113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.9241
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Middle ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Apical cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.0603
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.613318
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
linked	GeneRIF Biological Term Annotations	1.0	null
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52373
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68867
BRD-K61821542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64548
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08104
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23187
auditory receptor cell development	GO Biological Process Annotations 2025	1.0	null
large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895049
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68067
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47402
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
lymphoepithelioma-like thymic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918616
trimethadione-4165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905608
BRD-K69805180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09431
Spiral organ cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.049168
BB-44-SX65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207446
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0593
responsible	GeneRIF Biological Term Annotations	1.0	null
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66008
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04068
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.81992
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13044
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066661
Appendicitis_Appendix_GSE9579	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43252
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_S3I-201_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151161
AIDA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15274
retinal degeneration	MPO Gene-Phenotype Associations	1.0	null
Kidney cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879062
SCAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.21501
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2703
Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34904
decreased cholesterol level	MPO Gene-Phenotype Associations	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203543
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236003_0_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00119
ear morphogenesis	GO Biological Process Annotations 2023	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.875344
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92627
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85573
HEI-OC1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
OVCA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00668871
BRD-K16598630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06286
BRD-K31093279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5632
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.515
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29058
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.8322
NCIH1693	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61623
ATP6V1E1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988345
MAPK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518851
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AURKA_knockdown_89_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.92701
abnormality of the cerebellum	HPO Gene-Disease Associations	1.0	null
USP8	Pathway Commons Protein-Protein Interactions	1.0	null
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW403	CCLE Cell Line Gene Expression Profiles	1.0	2.04105
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253578
protein localization	GO Biological Process Annotations 2023	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stereocilium	GO Cellular Component Annotations 2015	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.84
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68635
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
hypertension	GWASdb SNP-Disease Associations	1.0	0.694052
PLEKHA5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2751
Leber congenital amaurosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S27_LF_C2_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
retinitis pigmentosa	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
cochlear degeneration	MPO Gene-Phenotype Associations	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285777
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18189
BRD-K12328371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73409
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879843
BRD-K47983010_BX-795_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EPCAM_OE_GDS4887_343_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02083
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972685
A549_Rucaparib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123674
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071734
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08596
LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13382
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.650026
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_4_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
FA-56-WH26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228963
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
increased or absent threshold for auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
aplasia/hypoplasia of the cerebellum	HPO Gene-Disease Associations	1.0	null
BRD-K69158405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19992
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
NTSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044552
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.63008
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90672
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43958
PLEKHA7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K90475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10973
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04254
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907098
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.734145
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear outer hair cell degeneration	MPO Gene-Phenotype Associations	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.625342
Retinitis pigmentosa 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13749
Microvillus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23333
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20662
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69028
abnormal outer hair cell stereociliary bundle morphology	MPO Gene-Phenotype Associations	1.0	null
RANBP17	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 103	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	3.10125
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.137
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0131
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.911
GOPC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17133642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01979
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47849
Autosomal dominant nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.156
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05781
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.68094
biological_process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0914
Autosomal Recessive Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
Perturb_14571_OE_JUN_SRP315909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ipex	GeneRIF Biological Term Annotations	1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57296
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
RBM34_02_121	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.96963
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02518
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Perturb_7040_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.66938
LS1034	CCLE Cell Line Gene Expression Profiles	1.0	2.42309
ATP6V0C	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Stereocilia coupling link	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VAPB	Pathway Commons Protein-Protein Interactions	1.0	null
specific	GeneRIF Biological Term Annotations	1.0	null
Usher Syndromes	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885403
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5190-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	DepMap CRISPR Gene Dependency	1.0	6.21527
complete	GeneRIF Biological Term Annotations	1.0	null
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36122
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06938
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
Visual Impairment	DisGeNET Gene-Phenotype Associations	1.0	null