association	dataset	threshold value	standardized value
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	2.0293
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.013
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0427
organelle	GO Cellular Component Annotations 2015	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20236
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47234
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15163
EC-GI-10	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81672
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.40712
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.57895
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45209
nucleus	GO Cellular Component Annotations 2025	1.0	null
NCI-H345	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18347
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9872
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981473
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7944
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1276
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	1.78635
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
cysteine-type deubiquitinase activity	GO Molecular Function Annotations 2023	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.8128
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	1.34044
Squamous Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982241
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52706
EJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58685
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10636
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914259
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2032
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5519
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2861
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17526
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
ubiquitinyl hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988651
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62852
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19982
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9722
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	3.24295
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26057
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9555
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825658
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57106
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1849
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7526
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47234
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07905
BL6340 (ANKRD17)	NURSA Protein Complexes	1.0	null
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.58719
CBX1	Pathway Commons Protein-Protein Interactions	1.0	null
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82402
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51776
FOXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68254
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05515
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.16167
RCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47132
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8097
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCC70	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
496100439_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24174
cellular macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	2.18886
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872647
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908689
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.44232
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58043
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936174
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44171
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81603
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84944
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.7833
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44982
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51135
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987845
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9938
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9423
FBXO42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52156
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3303
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8166
496100394_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01189
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10453
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33916
endoplasmic reticulum	GO Cellular Component Annotations 2015	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
BDCM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47728
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX60L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02813
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7368
PMC6325847-12935_2019_725_MOESM3_ESM.xlsx-Suppl_T2a-Table_S2a_Strelka_Calls_for_somatic_Nonsynonymous_AA_changes_allelic_frequency_0_1_identified_in_each_LGSC_cell_culture_by_WES_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02959
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4806
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8841
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82459
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62293
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7417
KO52	CCLE Cell Line Gene CNV Profiles	1.0	2.29427
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00419
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22018
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17558
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23001
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
regulation of programmed cell death	GO Biological Process Annotations 2025	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6855
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
QTRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59371
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.6013
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31235
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
GSE169617_1_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02959
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76019
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15184
modification-dependent macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5011
nucleus	GO Cellular Component Annotations 2023	1.0	null
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6625
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32274
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74918
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50424
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12886
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00803
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26824
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35829
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7219
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45723
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14634
cysteine-type deubiquitinase activity	GO Molecular Function Annotations 2025	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9161
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52319
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876595
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8639
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	1.0	2.51677
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
Peptidase C19, ubiquitin carboxyl-terminal hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4033
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826076
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23827
deubiquitinase activity	GO Molecular Function Annotations 2023	1.0	null
Intrinsic component of peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.289
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987845
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64875
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872647
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6727
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12093
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2721
PMC12081856-41420_2025_2522_MOESM6_ESM.xlsx-Sheet_1-Table_S4_Complete_Gene_List_of_the_MEblack_Gene_Module_and_the_DUB_Family_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8107
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29799
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2828
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	1.54439
MAGI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58319
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1361
MIA-PACA-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02999
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2527
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3481
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942885
biological_process	GO Biological Process Annotations 2015	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02925
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78086
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58943
cysteine-type peptidase activity	GO Molecular Function Annotations 2025	1.0	null
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01618
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84271
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18505
proteolysis	GO Biological Process Annotations 2015	1.0	null
IA-LM	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36296
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4493
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933403
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.56391
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
protein modification by small protein removal	GO Biological Process Annotations 2023	1.0	null
proteolysis involved in cellular protein catabolic process	GO Biological Process Annotations 2015	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6268
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98034
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.15723
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7952
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.86197
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914259
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9888
cellular_component	GO Cellular Component Annotations 2015	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
NCI-H2126	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20526
regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
NCIH2023	CCLE Cell Line Gene CNV Profiles	1.0	1.63856
ATP5PO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76476
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9659
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32763
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12271
Ubiquitin specific protease, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81672
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2532
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858487
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39074
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16424
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.279
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52002
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0285
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
HLC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84786
USP17L28	Pathway Commons Protein-Protein Interactions	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.961726
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933403
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942229
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.38141
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21842
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4759
TC32	CCLE Cell Line Gene CNV Profiles	1.0	1.62654
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03445
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.113
NCIH441	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93824
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.61651
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3675
regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
Small_Intestine-small intestine goblet cell	Tabula Sapiens Gene-Cell Associations	1.0	1.56525
A253	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34387
TP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37498
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99516
TMSB15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01922
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.73604
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
cellular process	GO Biological Process Annotations 2015	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3333
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67141
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858487
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85863
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
metabolic process	GO Biological Process Annotations 2015	1.0	null
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
NCI-H650	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6309
deubiquitinase activity	GO Molecular Function Annotations 2025	1.0	null
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72376
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	3.59539
BTF3	Pathway Commons Protein-Protein Interactions	1.0	null
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83439
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63789
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0714
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10636
SET	Pathway Commons Protein-Protein Interactions	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
USP26	Pathway Commons Protein-Protein Interactions	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62293
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00467
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07935
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4019
SW1710	CCLE Cell Line Gene CNV Profiles	1.0	1.39588
Sperm glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.012
SUIT2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55608
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2537
SW1271	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
ME1	CCLE Cell Line Gene CNV Profiles	1.0	1.55808
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62875
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42981
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09085
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.162
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7258
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1373
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872647
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858487
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5093
Hyaluronan/mRNA-binding protein	InterPro Predicted Protein Domain Annotations	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4231
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92057
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
endopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858487
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81532
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8591
SW403	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42389
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4416
DAN-G	COSMIC Cell Line Gene CNV Profiles	1.0	2.15817
T24	CCLE Cell Line Gene CNV Profiles	1.0	1.35237
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-3.05733
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9653
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00419
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963659
BL2852 (MED18)	NURSA Protein Complexes	1.0	null
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16149
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46975
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0831
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3314
LRP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07486
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99286
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826355
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50424
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
CPCN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65974
NACAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKNMC	CCLE Cell Line Gene CNV Profiles	1.0	1.35237
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6474
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
RH41	CCLE Cell Line Gene CNV Profiles	1.0	1.62466
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HAL-01	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
cysteine-type peptidase activity	GO Molecular Function Annotations 2023	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851713
SBC-5	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94301
cell part	GO Cellular Component Annotations 2015	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6584
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23133
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	2.10001
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34547
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.887
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4723
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6975
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.456
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.51673
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826076
KP3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29329
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32779
cysteine-type endopeptidase activity	GO Molecular Function Annotations 2023	1.0	null
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
modification-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44933
GSE143782_6_v_8_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47012
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39541
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18088
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
SCLC21H	CCLE Cell Line Gene CNV Profiles	1.0	1.66768
SKM-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1473
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.76634
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881205
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7881
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3531
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26057
macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57106
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05515
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.428
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935314
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59983
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5887
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14778
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
ZNF223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90007
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.85065
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63521
Ubiquitin specific protease domain	InterPro Predicted Protein Domain Annotations	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
nucleus	GO Cellular Component Annotations 2015	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4196
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9365
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4805
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
DANG	CCLE Cell Line Gene CNV Profiles	1.0	2.41455
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7374
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3673
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07531
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70451
ADAMTS1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57053
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00667
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57606
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3129
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.69997
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84271
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81603
RCHACV	CCLE Cell Line Gene CNV Profiles	1.0	1.34923
intracellular part	GO Cellular Component Annotations 2015	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32763
NCI-H292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9717
THP-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.86003
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17558
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876595
KCNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91847
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6691
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8368
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6202
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32355
USP17L2	Pathway Commons Protein-Protein Interactions	1.0	null
protein deubiquitination	GO Biological Process Annotations 2023	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8176
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7176
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.719078
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
regulation of programmed cell death	GO Biological Process Annotations 2023	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3939
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13949