association	dataset	threshold value	standardized value
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0334
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28966
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61575
autosomal genetic disease	GWASdb SNP-Disease Associations	1.0	0.270974
TP63	ChEA Transcription Factor Targets	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201454_0_v_2_ftcd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34963
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGI3	Pathway Commons Protein-Protein Interactions	1.0	null
EGR3_01_212	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59384
IRF2_01_100	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60606
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8422
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915114
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07353
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ubiquitin-like protein-specific protease activity	GO Molecular Function Annotations 2015	1.0	null
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.35985
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.21552
layer 3 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0761
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17454_KO_Insr/Igf1r_SRP091479	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.72635
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15472
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44574
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Perturb_11418_OE_HOXD13_SRP297429	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.36575
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980207
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08171
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39038
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85188
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49348
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884197
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.995678
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965301
MCF7_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142312
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984858
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49061
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68754
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.60653
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.057738
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate white layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04907
PMC10350897-j_biol-2022-0528-S1.pdf-181-USF2_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11416_KD_RB1_SRP271262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.725286
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1569
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00566
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37309
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65431
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827739
MCF7_Andarine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128151
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
PMC10563216-12917_2023_3758_MOESM2_ESM.xlsx-LPS-Andro_vs_LPS-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20469
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7408
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19132
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73092
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
PMC3064265-NIHMS252278-supplement-3.xls-A_Interactions-Supplementary_Table_2_DUB_data_No_Control_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22145
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07921
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14704
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879419
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06868
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5149
hsa-miR-4695-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1642
M140325	DepMap CRISPR Gene Dependency	1.0	2.18859
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16692
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03497
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.0444
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ewing's sarcoma family tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3143
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
DU145	DepMap CRISPR Gene Dependency	1.0	2.13044
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.21661
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
translesion synthesis	GO Biological Process Annotations 2023	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Septic Shock_Whole blood_GSE9692	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.3014
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892508
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50092
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4252
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910921
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34183
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.37701
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58788
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ubiquitin-like protein peptidase activity	GO Molecular Function Annotations 2025	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	2.23566
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5276
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.44337
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44008
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
POU5F1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14219
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92872
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	3.69546
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-SU-A7E7-01A-22R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.909234
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885823
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14329
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838594
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80261
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22286
MTF2	ChEA Transcription Factor Targets	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.08738
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.458433
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
lateral terminal nucleus of the accessory optic tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12655
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10464
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.79866
CEBPB	ENCODE Transcription Factor Targets	1.0	null
MCF7_Fedratinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127083
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922804
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86601
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.14336
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0755
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4085
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56036
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1119
PMC9225015-elife-72879-supp1.xlsx-DUB_CRISPR_library-Unnamed_3_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53288
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23473
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831647
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0605
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-874	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.656649
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841422
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74523
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843806
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07262
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02994
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12828
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16322
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3692
E2F4	ENCODE Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26079
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.82455
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56855
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07236
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4729-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1017-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.704
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anemia	GWASdb SNP-Phenotype Associations	1.0	0.347205
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87404,GSE87812_2_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.10562
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951644
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.889795
hsa-miR-490-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68836
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02266
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43Y-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cysteine-type peptidase activity	GO Molecular Function Annotations 2023	1.0	null
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10545
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866008
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54327
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57009
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903224
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975041
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.090804
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918205
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36287
MCF7_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139396
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37769
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.53086
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3312
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17722
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12115
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-363	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10145
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26148
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4738-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC6	CCLE Cell Line Gene Expression Profiles	1.0	1.58204
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0214
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68532
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.43008
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Lung squamous cell carcinoma_LUSC_TCGA-94-7557-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1161
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280562
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KD	DepMap CRISPR Gene Dependency	1.0	7.25946
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99313
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.208
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17074
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986521
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.233
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.59264
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42044
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06758
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.266858
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02548
Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14548
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918205
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828407
E2F1	ENCODE Transcription Factor Targets	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08458
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12035_KO_Ccr2_SRP247656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7102
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4141
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INCB 3284	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99908
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1302
regulation of proteasomal protein catabolic process	GO Biological Process Annotations 2015	1.0	null
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26388
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.043855
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54254
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01138
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0389
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862297
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924903
NCIH524	CCLE Cell Line Gene CNV Profiles	1.0	2.07703
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82918
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988712
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24408
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01728
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_11405_KD_RB1_SRP099582	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.9586
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_downreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80261
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39847
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23295
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33748
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04547
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.8629
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62268
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03381
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70135
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of protein catabolic process	GO Biological Process Annotations 2015	1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26631
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34183
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39016
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4521
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KARPAS-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.873335
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12060_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954926
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3005
GSE238018_1_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858341
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838394
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AM966	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13901
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5389
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85254
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139452
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.873558
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4932
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Perturb_5283_Mut_Tet2_SRP111192	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59752
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69369
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10162
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18985
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
translesion synthesis	GO Biological Process Annotations 2025	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-GH-A9DA-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.879748
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24057
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1866
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896628
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03926
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4892
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19154
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548am	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Lactate (calcium)_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0090359
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37106
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04907
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39251
Benethamine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.44
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
proteolysis	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.091
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19896
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41447
proteasomal protein catabolic process	GO Biological Process Annotations 2015	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.942532
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17533
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	1.79501
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851289
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2573
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09291
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.855867
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11124
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.138065
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931567
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7480-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18112_KO_Eed_SRP132909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.60833
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36525
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8888
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00566
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886934
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33816
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13662
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82159
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301622
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00566
H3K27me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186844
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915497
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06937
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP2K1_druginhibition_172_GSE39984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.25902
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548aj	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829562
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4566-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41084
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.11116
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0268
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11232
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66744
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16154
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.961107
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887538
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24814
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49946
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2906
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05044
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08487
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.24056
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8161
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177416
PMC6828764-41419_2019_2062_MOESM2_ESM.xlsx-GATA3_UTX_promoter_gene-ENSEMBL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01778
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_TG101209_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0308454
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39265
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.51083
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95299
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21096
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.14856
STAT6_01_85	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59137
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.566629
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12665
Helab	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein deubiquitination	GO Biological Process Annotations 2015	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57449
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28966
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
ZNF180_02_177	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.11548
Perturb_4151_KO_Csmd3_SRP343147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.672
ARID3A	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57216
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49571
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16538
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
placenta_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.0493
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966634
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_250_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.9965
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Rectum adenocarcinoma_READ_TCGA-EI-6511-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200502_0_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880683
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
RVH421	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92912
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5625-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995945
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40247
hsa-miR-558	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3256
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
Ethynyl Estradiol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1267
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2529
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1476
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3082
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Superior colliculus, motor related, intermediate white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01138
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
all	GWASdb SNP-Phenotype Associations	1.0	0.034018
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.380007
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94226
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14673
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85254
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAS acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212192
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58161
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4138
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03058
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860619
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11515_KD_FKBP4_SRP282050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5397
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12391
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3336
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43152
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0623
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Ubiquitin specific protease, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PF-8380	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10309_KO_Nos3_SRP286435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.04184
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4129
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835599
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.968051
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28245
Guanethidine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
LC1SQSF	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50097
Atglistatin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
ISG15-specific peptidase activity	GO Molecular Function Annotations 2023	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31084
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HY-50713	DeepCoverMOA Drug Mechanisms of Action	1.0	0.49
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40614
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926718
Site of DNA damage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
GSE127205_1_v_0_asf1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_3_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	2.74227
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917001
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	Reactome Pathways 2024	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08965
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78L-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06868
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06442
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77638
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904415
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853449
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47448
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.05198
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925196
hsa-miR-4666-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8184
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01138
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.045972
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65858
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080042
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02341
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14711
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4626
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847802
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10072
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0741
cysteine-type peptidase activity	GO Molecular Function Annotations 2015	1.0	null
GSE213632_1_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05918
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07594
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2234
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
MAX	ENCODE Transcription Factor Targets	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TR146	DepMap CRISPR Gene Dependency	1.0	2.73128
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8778
Brain Lower Grade Glioma_LGG_TCGA-DU-7299-01A-21R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_to_Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8166-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FN3KRP	Pathway Commons Protein-Protein Interactions	1.0	null
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.919135
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00133
YWHAE	Hub Proteins Protein-Protein Interactions	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71957
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
disease	GWASdb SNP-Disease Associations	1.0	0.03377
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05588
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06905
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894261
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966402
TBP	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932925
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0683
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25312
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05226
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-376c	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10915
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872182
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50135
LOUCY	CCLE Cell Line Gene Expression Profiles	1.0	1.56042
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
protein modification by small protein removal	GO Biological Process Annotations 2015	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9418
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
A253	CCLE Cell Line Gene Expression Profiles	1.0	1.48634
TCF12	ENCODE Transcription Factor Targets	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85865
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10155
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4699-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
catabolic process	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182595
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.41884
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16392
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.986833
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877697
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05852
Atrophy	CTD Gene-Disease Associations	1.0	1.2821
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828362
KCL22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58448
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44152
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06327
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3137	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83477
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22065
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51694
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11124
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3007
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08521
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05229
PMC7910580-41467_2021_21715_MOESM3_ESM.xlsx-DUBs_screen-Supplementary_Data_1_Results_of_DUB_shRNA_screen_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203-2004(H5N1)_3Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.41277
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.554022
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30989
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85403
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.35855
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6006
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831468
MCF7_Pirarubicin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137036
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AKT1_knockout_210_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.09208
ELK3_01_318	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59371
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39254
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844276
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ubiquitin-like protein peptidase activity	GO Molecular Function Annotations 2023	1.0	null
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nuclear splicing speckle	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20156
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829387
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915174
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.239293
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8982
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29028
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.38751
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.980643
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29122
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864744
Lung adenocarcinoma_LUAD_TCGA-55-7907-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04113
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200099_2_v_0_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9225015-elife-72879-supp6.tsv--DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950024
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87477
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05044
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93653
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26654
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01797
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.731
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.970407
Ethoxzolamide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1028
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859658
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03083
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.694
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44574
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8848
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920559
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12655
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.990189
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.133488
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06958
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.27845
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31965
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13524_KD_Brd9_SRP333303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.49991
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15777
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10733
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23598
Perturb_11853_KO_Gdf2/Bmp10_ERP128742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.11115
SOX17	ChEA Transcription Factor Targets	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAH	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22363
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964223
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13977
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
peptidase activity, acting on l-amino acid peptides	GO Molecular Function Annotations 2015	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926409
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3561
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840247
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4459
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4103
SKHEP1	CCLE Cell Line Gene CNV Profiles	1.0	1.3355
Vismodegib_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00924147
mantle zone of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01138
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938841
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01138
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37769
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05044
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.79045
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89721
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1179
ZEB1	ENCODE Transcription Factor Targets	1.0	null
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	HPA Tissue Protein Expression Profiles	-1.0	-0.747006
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	1.66669
2,6-Dichlorophenethylamine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
GSE162276_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	1.5217
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.041004
RELA	ChEA Transcription Factor Targets	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095586
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00566
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17704
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.44612
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164569
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10396
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Panc-02 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.337
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924186
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0984
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4199_KO_Fmr1_SRP075646	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.50457
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.096045
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0034
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.34
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
ventral tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02341
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06138
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
prostate	GTEx Tissue Gene Expression Profiles	1.0	1.67256
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1855
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54327
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950891
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22297
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-KF-A41W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.66349
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.14912
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Hesperadin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0289171
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.21661
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FTC238	CCLE Cell Line Gene Expression Profiles	1.0	1.43848
Hexylresorcinol_CFPAC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0127108
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74967
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.02447
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02619
regulation of cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.50386
Ubiquitin specific protease domain	InterPro Predicted Protein Domain Annotations	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06807
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.039179
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05038
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05229
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Lung adenocarcinoma_LUAD_TCGA-05-4434-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7468443-Data_Sheet_5.xlsx-PolyIC_6h_over_LPS_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
modification-dependent macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52127
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945073
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
CDK14	Kinase Library Serine Threonine Kinome Atlas	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40071
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848754
GSE92548_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117623
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27995
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50548
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.21661
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4520a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5287
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
autosomal recessive disease	GWASdb SNP-Disease Associations	1.0	0.39676
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940784
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.41313
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00831
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29649
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0623
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.239293
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22344
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01215
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88663
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0553
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913337
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.922449
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06445
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A720-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISG15-specific peptidase activity	GO Molecular Function Annotations 2025	1.0	null
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8482521-mmc13.xlsx-Phosphosites_48vhr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54065
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45953
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RB-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.279195
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35445
GSE254526,GSE254528_0_v_1_phf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCK81	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22818
SNUC2A	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03311
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06347
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H358 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81826
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5581
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNA ligase IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.42859
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of proteolysis involved in cellular protein catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38988
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10934
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64872
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05889
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39135
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_SGI-1776 free base_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118588
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6446
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_14610_KD_SIK3_SRP118895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.00002
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953176
CDK17	Kinase Library Serine Threonine Kinome Atlas	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940081
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07772
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935701
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876116
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151394
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.21661
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4665
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207169
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.62344
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	3.35559
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5987
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04167
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35745
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139977
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5298
RBBP5	ENCODE Transcription Factor Targets	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
postreplication repair	GO Biological Process Annotations 2023	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863335
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Choline	CTD Gene-Chemical Interactions	1.0	null
LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PINK1	Kinase Library Tyrosine Kinome Atlas	1.0	96.015
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60647
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39447
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.229294
Perturb_202_KO_Carmil3_SRP168358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25479
Site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873576
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943706
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883465
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995127
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04273
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OAW-28	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.05196
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875147
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33434
MKN74	CCLE Cell Line Gene Expression Profiles	1.0	2.10243
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.760054
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TP-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88069
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87065
MCF7_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013303
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68532
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986268
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18289
lm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920137
4,4'-Dimethoxybenzil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9515
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03825
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11880379-41467_2025_57480_MOESM3_ESM.xlsx-SOX9_RIME_Limma-Gene_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44271
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57591
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H-1299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
TRIM28	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6711
LN443	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60029
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1501
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.946459
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.63049
HS695T	DepMap CRISPR Gene Dependency	1.0	2.01356
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6444
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05472
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08351
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09936
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3449
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.77331
FOSL1	ENCODE Transcription Factor Targets	1.0	null
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07648
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-155	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Brain Lower Grade Glioma_LGG_TCGA-DH-5144-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948325
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16052
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34076
MCF7_Dasatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214017
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OC315	CCLE Cell Line Gene Expression Profiles	1.0	1.44611
JUND	ENCODE Transcription Factor Targets	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
sacrospinalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24431
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.919135
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45564
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.67761
RCM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942211
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.729
RFX5	ENCODE Transcription Factor Targets	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCIH1869	DepMap CRISPR Gene Dependency	1.0	3.03782
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0058
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15955
TC-71 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24057
MCF7_Lapatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135617
MCF7_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130885
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4141
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836836
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2093
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4373
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56036
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2416
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19703
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.91582
Perturb_11075_KO_Rictor_SRP097622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.48721
ELK1	ENCODE Transcription Factor Targets	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.92049
Ewing's sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830588
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63215
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00997
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Familial adult myoclonic epilepsy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3799
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.5182
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.755
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7094_OE_miR128_SRP126105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.84978
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24814
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05544
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0535
LS513	CCLE Cell Line Gene Expression Profiles	1.0	1.87672
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5663
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.03149
PMC12855127-Table1.xlsx-Sheet1-Table_S1_A_total_of_576_E3_genes_and_95_DUB_genes_were_identified_in_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08065
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07095
Lung adenocarcinoma_LUAD_TCGA-50-5932-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.45277
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53735
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Liver enzyme levels (alkaline phosphatase)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.61549
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64909
hsa-miR-4642	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11293
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.948962
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01688
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06937
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	3.39762
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136196
JEKO-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.05196
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54327
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937636
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15041
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20594
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSME3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927302
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02634
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.830371
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942211
Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4013
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.053963
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864991
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097296
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01584
Perturb_17685_KO_Pgr_SRP365149	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.44125
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0136
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59186
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3377
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01817
A549_Ellagic acid_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134623
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10181
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.988809
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27885
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58438
Perturb_14840_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.79731
EGR1	ENCODE Transcription Factor Targets	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.08005
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00057
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33816
GSE178714_6_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
S-Adenosyl-L-methionine (disulfate tosylate)_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0250993
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4586_KO_Socs3_SRP099234	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.9515
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4645-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
(RS)-PPG	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.95
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5848
YD8	CCLE Cell Line Gene CNV Profiles	1.0	1.4327
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31258
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48073
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51165
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304735
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR31	CCLE Cell Line Gene Expression Profiles	1.0	1.89429
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8616-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14768
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14883
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.653
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.32028
GSE126127_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1393
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24945
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECGI10	CCLE Cell Line Gene Expression Profiles	1.0	1.35105
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19896
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.482756
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	16.7722
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914667
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917556
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217673
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15029
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.898263
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0525
Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22509
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829576
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7104-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2892
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A	ChEA Transcription Factor Targets	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825778
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bromopyruvic acid	DeepCoverMOA Drug Mechanisms of Action	1.0	0.59
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7619
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4738-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
PMC8225676-41467_2021_24150_MOESM4_ESM.xlsx-DUB_ranking_siRNA_screening-DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08512
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840667
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24057
GSE181749_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235828_3_v_2_igf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31392
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897203
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03368
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21741
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.24401
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33556
ZMIZ1_02_181	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67807
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05083
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4595
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35111
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834349
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
DUBm complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4326
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.03964
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1841
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843806
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983744
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12655
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
697	DepMap CRISPR Gene Dependency	1.0	2.18778
GSE200502_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.38071
CHK1_KD_GSE54267_671_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COLO680N	CCLE Cell Line Gene Expression Profiles	1.0	1.43631
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9908924-41467_2023_36246_MOESM4_ESM.xlsx-Supplementary_data_2-DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11353_KD_METTL3_SRP292229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.94705
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76724
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827098
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50724
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3944256-cddis201440x1.xls-Primary_Screen_Results-Supplementary_Table_1_Synthetic-Lethal_siRNA_DUB_Screen_for_Mcl1_antagonists_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159647
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.849
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508376
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
PMC6828764-41419_2019_2062_MOESM2_ESM.xlsx-GATA3_UTX_promoter_gene-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954412
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877697
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225383
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35991
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4277	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975041
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14194
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71657
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0519
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.97
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26017
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
W-13 HCl	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.44
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9756
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3712200-584604.f1.pdf-28-GRHL1_GRHL1	Rummagene Transcription Factor Associations 2026	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
postreplication repair	GO Biological Process Annotations 2025	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
A549_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116133
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_significantly_downregulated_739_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63072
ESRRB	ChEA Transcription Factor Targets	1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72926
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915068
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21299
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8358
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54972
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887857
Perturb_14609_KD_SIK3_SRP118895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.69554
LOK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990854
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29437
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.08343
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2163_KD_Chd8_SRP062904	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.45033
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834634
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01728
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.54334
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19667
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11663
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.842745
Entospletinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
I3C	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3622b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.40752
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4865
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883806
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8785
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23647
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60959
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17533
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01223
istmes2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
MYBL2	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63072
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870422
NFIC	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175815
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4433
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4074
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.943262
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.939025
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54956
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
Sitagliptin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02641
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834579
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.984196
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.184422
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DNA synthesis involved in DNA repair	GO Biological Process Annotations 2023	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862595
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836464
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849751
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2215
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
ubiquitinyl hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
c-MYC_KD_GDS2526_113_human_MDA-MB-231 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46205
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
MCF7_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157539
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981516
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13858
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01728
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.74751
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.138065
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4585_KO_Socs3_SRP074146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.9515
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.518
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848396
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40244
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31058
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04845
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60818
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	HPA Tissue Gene Expression Profiles	1.0	1.38123
LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.66752
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.841251
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04907
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01686
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6678
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.13552
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88447
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subceruleus nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54327
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8482521-mmc13.xlsx-Phosphosites_12_hr_48_hr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1724
Perturb_4171_KO_Banf1_SRP302680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.7833
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Vandetanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00918713
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0816
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50092
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9594
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.902022
NB13	DepMap CRISPR Gene Dependency	1.0	3.82033
NCIH841	CCLE Cell Line Gene CNV Profiles	1.0	2.66655
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01728
HS944T	DepMap CRISPR Gene Dependency	1.0	2.28511
CEBPB_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996794
MCF7_Tranylcypromine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132135
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
PMC3290552-pone.0032232.s005.xls-ErbB2-KD_vs_NT-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.537527
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855227
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944657
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.21661
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.08366
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.52978
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3417
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37164
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.167694
PMC6325590__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_17918_KO_Snca_SRP377748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.37237
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962368
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GATA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCNI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93844
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49646
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.86662
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9671
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4593
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13286
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14548
SNU520	CCLE Cell Line Gene Expression Profiles	1.0	1.42003
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proteolysis involved in cellular protein catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
lung cancer	GWASdb SNP-Disease Associations	1.0	0.624931
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05482
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918205
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.26713
MCF7_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131844
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68836
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46455
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917006
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
liminal part of alar r1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14219
MCF7_Fedratinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146615
biological regulation	GO Biological Process Annotations 2015	1.0	null
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854069
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
DNA Damage Bypass	Reactome Pathways 2024	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18267
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58349
Termination of translesion DNA synthesis	Reactome Pathways 2024	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65862
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	1.87827
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14745
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828407
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52726
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42999
NR2F2	ENCODE Transcription Factor Targets	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22341
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16392
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.920781
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.942334
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BEC	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.963906
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210284
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1290	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5276
PMC8329168-41418_2021_763_MOESM8_ESM.docx-0-DUB_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZEB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arbutin_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.010635
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17454
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19236
A549_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149214
NANOG	ENCODE Transcription Factor Targets	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_4_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11603793-12964_2024_1953_MOESM1_ESM.pdf-43-TET3_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25751
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56036
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67793
FIZZ2_KO_GDS4902_408_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89974
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978764
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21709
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_12300_KD_METTL3_ERP137121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49218
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13723
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946427
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.91852
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64011
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920167
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26247
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WSU-DLCL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.21661
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131402
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1136
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56546
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42648
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear speckles	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19526
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20258
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16834
hsa-miR-548x	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0311873
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22919
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951604
Acute pancreatitis_Pancreas_GSE3644	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.769627
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99787
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173682
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QZ-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fat_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2778
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901365
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23503
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	2.06351
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1848
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	2.50987
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-A_FUS-DDIT3_vs_both_controls-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.921027
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0748
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7592-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63215
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34183
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50571
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55466
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828407
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.10888
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3622a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11124
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861449
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53569
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ENL-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11858
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65975
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34144
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.51816
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906334
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39911
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monogenic disease	GWASdb SNP-Disease Associations	1.0	0.24194
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4655
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98793
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04868
GSE181959_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01879
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034101
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8526018-KAUP_A_1856493_SM1378.xlsx-Table_S5-_DUB_genes-Table_S5_Compared_deubiquitinating_enzyme_genes_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19703
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KAT2B_02_184	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.5025
Memory Disorders	CTD Gene-Disease Associations	1.0	1.19509
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Basimglurant	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.51116
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43187
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31965
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28858
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925992
CEBPD	ENCODE Transcription Factor Targets	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10145
CCAR2_02_146	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66297
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.80709
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28353
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26125
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01817
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.54322
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56662
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42449
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-70-6722-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13627
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93836
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14782
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62107
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5814
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4680-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DIFI	DepMap CRISPR Gene Dependency	1.0	3.34149
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842894
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0036
FOSL1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4787_KD_Akap8_SRP075747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.72464
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01245
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17333_OE_NANOS1_SRP216951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.07065
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Piccolo NuA4 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846202
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05044
Hypertension	CTD Gene-Disease Associations	1.0	1.02114
ELF1	ENCODE Transcription Factor Targets	1.0	null
mhhes1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18988
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17631_KD_Rictor_SRP224571	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.9245
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TZM-bl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0022
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111459
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215148
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00566
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863956
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6368
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3138
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3724
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4719
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30382
HCC366	CCLE Cell Line Gene Expression Profiles	1.0	2.32345
GSE178714_3_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
VUF11207	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
PMC11880379-41467_2025_57480_MOESM3_ESM.xlsx-FOXP1_RIME_Limma-Gene_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRISC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63072
Carbamazepine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEK-293A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0789
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45152
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9857	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.42119
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857632
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4838354-supp_gkv1491_nar-01150-met-k-2015-File010.xlsx-ChIP-seq_defined_target_genes-PBX1_and_Notch3_common_target_gene_list_621_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49629
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Unnamed_8_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935076
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1509
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-108-MSX1_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9498
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01728
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.53145
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06198
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4499
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14527_KO_Foxa2/Gata4/Nr5a2/Ptf1a_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.892513
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.876
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65142
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27409
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19614
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2739
MM253	DepMap CRISPR Gene Dependency	1.0	3.52995
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.842908
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25793
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231720,GSE231724_3_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.06131
SFN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23967
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980228
Fatty Liver	CTD Gene-Disease Associations	1.0	1.51004
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01804
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.71753
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23287
hsa-miR-3677-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
intramuscular adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45286
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97961
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84345
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891723
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2127
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.862793
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.892513
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16538
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439387
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.647626
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2167
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892508
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Ewing's family tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0263
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06363
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82918
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13742_KO_Nfib_SRP096738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52578
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07353
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955347
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921283
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.08894
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13457
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955625
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43742
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882004
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CZC-25146	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60899
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34806
deep gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03642
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
runx1_18671852_e8dot5_lof_mouse_gpl1261_gds1511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.461749
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
DNA synthesis involved in DNA repair	GO Biological Process Annotations 2025	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48102
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-1526-SM-3NMCK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853913
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37505
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.26917
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01923
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06941
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830553
YD38	DepMap CRISPR Gene Dependency	1.0	3.46624
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
hFOB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8308
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20806
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7049
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.6469
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40298
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66456
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995814
MCF7_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113189
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3PZ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06047
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5814
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29848
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54411
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856871
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAB	Hub Proteins Protein-Protein Interactions	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9448
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42019
regulation of cellular protein catabolic process	GO Biological Process Annotations 2015	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.5143
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2385
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09065
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943204
ZNF786	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48806
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13834
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50I-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5637 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19986
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327896
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909276
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.964333
Voriconazole_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00530659
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38649
15788672-Table1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_3241_OE_IK6_SRP136156	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.5654
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15869
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.10672
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948274
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24326
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38383
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02664
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43947
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03811
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68044
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.984546
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
YWHAB	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967289
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.04239
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173603
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08994
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34141
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Bosutinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133151
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.743072
Sildenafil	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Sarcoma_SARC_TCGA-X6-A8C4-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01881
HUO9	COSMIC Cell Line Gene CNV Profiles	1.0	2.15465
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941605
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-0.934755
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895702
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93824
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_OE_GDS4978_547_human_L428	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08264
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052057
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.482314
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30934
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08264
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14419
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155989
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970402
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865307
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34031
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
peptidase activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829576
Fenoldopam	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97346
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.1651
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960319
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894935
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.851362
SUPM2	CCLE Cell Line Gene Expression Profiles	1.0	2.12967
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rhombomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06868
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	4.30104
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10057
PMC12719073-mmc1.pdf-14-MYSM1_MYSM1	Rummagene Transcription Factor Associations 2026	1.0	null
r1 part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85254
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.65229
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	2.11922
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70964
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59849
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71893
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01758
Purvalanol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.60653
TE-441-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58627
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21242
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03464
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923236
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-17p13_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5367
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28298
A 1120	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2873
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
NK-92MI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46319
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10235
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71751
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857791
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
increased red cell sickling tendency	GWASdb SNP-Phenotype Associations	1.0	0.751382
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
cysteine-type peptidase activity	GO Molecular Function Annotations 2025	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4645
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11124
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933689
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	5.109
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995814
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Posterior parietal association areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15115
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934841
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4169
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
POMC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76296
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3047
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80261
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4838354-supp_gkv1491_nar-01150-met-k-2015-File011.xlsx-Differentially_expressed_genes-Differntially_expressed_PBX1_and_NOTCH3_common_genes_under_GSI_FC_1_3_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.35934
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54038
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.821366
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	1.0	0.88954
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1553
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153663,GSE153664_1_v_0_zeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944844
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36945
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7559
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.51082
NFYB	ENCODE Transcription Factor Targets	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.36419
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0237
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42184
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06583
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01879
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.56657
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	4.17506
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923434
MCF7_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0306096
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
MCF7_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172967
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967873
Arsenic	CTD Gene-Chemical Interactions	1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32917
MCF7_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106698
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1202
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44115
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09165
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDCD2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47318
PMC3348545-NIHMS263168-supplement-3.pdf-338-SOX15_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03769
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fumagillin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
PMC7833686-mmc5.xlsx-e_q1en30_v1-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951037
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2663
BCL3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.279195
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
OPM2	DepMap CRISPR Gene Dependency	1.0	2.02179
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3478
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02033
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.899317
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Prostate adenocarcinoma_PRAD_TCGA-VN-A88N-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
regulation of catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1056
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23503
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56185
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3963
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36066
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.14585
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46659
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2695
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37256
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19723
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.25773
FOXA1	ENCODE Transcription Factor Targets	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24057
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00119
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.871498
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7016
FOS	ENCODE Transcription Factor Targets	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Cetirizine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.72
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01891
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	3.08109
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898687
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03469
Perturb_5711_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.57934
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25557
C3A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF5	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC6459557-pbio.3000201.s012.xlsx-Sheet1-FOXD1_FOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48073
SFN	Hub Proteins Protein-Protein Interactions	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04072
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6474-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64148
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3225
MYOG	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22628
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855743
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Delta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.95212
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8254-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.723598
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0443
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08168
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.903915
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855123
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17259
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886705
hsa-miR-4535	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16122
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13545
MCF7_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015301
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14362_KD_SORBS2_SRP112756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.42648
prostate	HPA Tissue Gene Expression Profiles	1.0	1.06994
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143276
cellular macromolecule catabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827508
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-6.39113
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07389
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.846581
Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64046
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.98735
MCF7_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152773
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971521
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82721
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37373
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC95	CCLE Cell Line Gene Expression Profiles	1.0	1.56577
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920322
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.079542
MCF7_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148999
MAZ	ENCODE Transcription Factor Targets	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
GSE202434,GSE202438_7_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CCNT2	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BL2467 (SEC16A)	NURSA Protein Complexes	1.0	null
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Inflammation	CTD Gene-Disease Associations	1.0	1.52616
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959731
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838817
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Peptidase C19, ubiquitin carboxyl-terminal hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967799
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.3085
Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A61P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.530114
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19571
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23279
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05417
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08431
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0526-SM-32PM7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857922
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39385
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95774
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943977
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07032
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8575
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849011
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940506
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36586
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Field CA2, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24814
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12057_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841035
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24847
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46908
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41421
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37426
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111841
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23384
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00385
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872954
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900376
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ae	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.665599
PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Primary_S6P_positives_NOT_selected_for_retesting_with_the_4_individual_RNAi_used_in_the_intial_screen_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139579
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0763
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846516
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6149
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84573
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042706
GSE169590_6_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852835
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952613
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24654
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33473
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069799
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83398
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37828
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06394
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	1.51462
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91992
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12608
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73133
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.990078
protein modification process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.957794
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19843
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13571_KD_Islr_SRP160431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13436
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46715
MCF7_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128041
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83231
GSE137137_1_v_0_rcor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81854
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
MCF7_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152258
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18074
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6823
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02263
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964103
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34186
BL1000 (FANCI)	NURSA Protein Complexes	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7740_KO_Yap_SRP281854	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62993
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
CCK-81	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.05196
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39516
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99961
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11896
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858285
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7077-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65791
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8709
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.899249
ZNF143	ENCODE Transcription Factor Targets	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02341
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Crizotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166665
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24346
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE179002_3_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124611
EP300	ENCODE Transcription Factor Targets	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
GSE255432_7_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859882
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904901
cellular catabolic process	GO Biological Process Annotations 2015	1.0	null
m2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03642
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A769-01A-32R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06753
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
chr17_9685133_T_G_b38	GTEx eQTL 2025	1.0	3.024
16166195-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
Perturb_4638_KO_Nanog_SRP125837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.37343
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20212
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38782
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-656	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961781
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.02688
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.109552
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843806
mantle zone of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5276
A549_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134642
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37712
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1303	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73709
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953857
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43478
DC-45-WU45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227815
SCC-25	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50054
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38703
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85A-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8351-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.815935
JHUEM1	DepMap CRISPR Gene Dependency	1.0	4.73857
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07005
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3154
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.882284
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23793
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
hsa-miR-3189-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Perturb_1316_KO_Agl_SRP140441	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71344
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894332
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7375
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884265
DNA Repair	Reactome Pathways 2024	1.0	null
placenta_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.36871
UMUC16	DepMap CRISPR Gene Dependency	1.0	8.51049
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989324
NCIH1993	DepMap CRISPR Gene Dependency	1.0	12.1759
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13843
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38703
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28858
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934157
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
4h_cisplatin vs ctrl_mESC (Mouse) [22006019]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	-1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.55206
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29647
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.981531
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4005
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
RCOR1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949877
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30078
lateral part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61295
GSE162276_4_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7880901-NIHMS1649581-supplement-2.xlsx-DESeq_V7_1_and_3_vs_Ctrl_1to2_f-Table_S1_List_of_AR-V7-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7830_KD_PREP1_SRP113380	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.41537
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
Ewing's sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66534
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825044
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.935397
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2110	CCLE Cell Line Gene Expression Profiles	1.0	1.65927
Perturb_12850_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.29547
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31965
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57161
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059508
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11361_KD_METTL3_SRP292229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.05689
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37223
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934398
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978048
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873664
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.70372
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11879
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07968
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983444
NCIH2087	CCLE Cell Line Gene CNV Profiles	1.0	1.49009
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36388
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_11759_OE_Ddah1_SRP027595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.02816
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69099
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4131
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.281861
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05095
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2564
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25801
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82666
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.76033
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879876
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84169
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.4366
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8165
SAGA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5020_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18902
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13436
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38782
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.49179
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7697
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07927
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828407
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC4	DepMap CRISPR Gene Dependency	1.0	2.87196
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878712
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2932
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.59441
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186654_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5933-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14479
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49571
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06682
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.248091
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4245
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6379
Perturb_4227_KO_Ngr1_SRP098816	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22646
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05798
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58863
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13822
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11776
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995832
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82918
protein catabolic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63072
PMC11252405-41467_2024_50426_MOESM4_ESM.xlsx-Fig_S4c-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44136
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909228
Learning Disorders	CTD Gene-Disease Associations	1.0	1.6677
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981002
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14802
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCL161	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.94
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YWHAH	Hub Proteins Protein-Protein Interactions	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
L-NIL	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05802
MDA-MB-157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23874
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925709
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.82623
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15235
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.450683
sickle cell anemia	GWASdb SNP-Disease Associations	1.0	0.857874
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10871
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2989
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24057
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18538
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
Olvance	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LNZ308	CCLE Cell Line Gene CNV Profiles	1.0	1.60507
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zofenopril	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3236
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826724
cysteine-type endopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06239
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66348
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24039
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Conserved_gene_regulation_during_acute_inflammation_between_zebrafish_and_mammals_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05483
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.047423
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28281
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01593
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08292
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-2.08798
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21667
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A47Z-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29295
BACH1_02_188	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61298
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877697
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3953
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2989
PSS008	DepMap CRISPR Gene Dependency	1.0	3.44972
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.038642
organic substance catabolic process	GO Biological Process Annotations 2015	1.0	null
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374516
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921653
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15029
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
modification-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71654
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5558-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980426
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923679
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.282321
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0077
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	2.84447
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NuRD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06445
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9601
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.0123
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95437
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23647
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36886
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36401
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4954
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20469
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914396
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Boc-4mesyloxypiperidine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50528
PMC9225015-elife-72879-supp6.tsv--DUB_HUGO_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28109
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWS6-0426-SM-47JXH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903318
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4417
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r2 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02341
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7457
KDM5A	ENCODE Transcription Factor Targets	1.0	null
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2015	1.0	null
Uterus-epithelial cell of uterus	Tabula Sapiens Gene-Cell Associations	1.0	0.741081
Machado-Joseph disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIA-PACA-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6325590__F8	PFOCR Pathway Figure Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FD-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
L428	CCLE Cell Line Gene CNV Profiles	1.0	1.38938
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33816
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.296
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876608
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976238
MCF7_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112941
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6606
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334865
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SRSF4_02_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995814
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61802
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEK-293FT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00566
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GSE198165,GSE198166_9_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
preisthmic midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03642
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
No annotation - 6	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03737
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-22	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853047
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877697
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA2	ChEA Transcription Factor Targets	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
klf9_17379758_jejunum_lof_mouse_gpl339_gds2703	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.617359
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Ofloxacin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156709
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68905
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0065
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918884
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.89854
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5436
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7234
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869278
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ubiquitin-specific protease activity	GO Molecular Function Annotations 2015	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00628
Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32109
UPCISCC029A	DepMap CRISPR Gene Dependency	1.0	2.66558
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3668
MYC	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955659
Perturb_3543_KO_Atcb_SRP217493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887157
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35267
Cytoskeleton organization and intracellular signaling	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19679
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9469
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0931
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53532
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02341
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6855
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12687
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829576
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.259062
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10369
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anemia due to reduced life span of red cells	GWASdb SNP-Phenotype Associations	1.0	0.393792
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226724
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83419
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11533
GSE139239_3_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48462
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924337
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00258
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0836
longissimus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25681
Charcot-Marie-Tooth disease type 4C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45533
genetic disease	GWASdb SNP-Disease Associations	1.0	0.219079
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.52508
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2575
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02533
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05871
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16885
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.364394
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18279
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.05998
GTF2B	ENCODE Transcription Factor Targets	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07268
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33919
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56212
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63016
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8143797-elife-62857-fig4-data2.xlsx-TAZ-CAMTA1_ChIP_RNAseq_merged-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11999
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00375
LN464	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48458
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208796
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8143797-elife-62857-fig4-data2.xlsx-TAZ-CAMTA1_ChIP_RNAseq_merged-ENSEMBL_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11747033-Table1.xlsx-Sup_Table_S1-IFNy_LPS_TREATED_HMEC_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65544
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3203
RL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38163
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8729
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19275
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35555
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.48508
PMC12255818-41467_2025_61448_MOESM1_ESM.pdf-64-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
ABC1	CCLE Cell Line Gene Expression Profiles	1.0	1.52269
endopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9444
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SC-834 ()	NURSA Protein Complexes	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918205
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22011
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23843
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47951
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48073