association dataset threshold value standardized value GTEX-QEG5-0226-SM-2I5GI GTEx Tissue Sample Gene Expression Profiles 1.0 1.33221 u87 HPA Cell Line Gene Expression Profiles -1.0 -1.56947 Hoxc13_OE_GDS1890_174_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974596 YT COSMIC Cell Line Gene Mutation Profiles 1.0 null WDR36 Pathway Commons Protein-Protein Interactions 1.0 null VNN1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00509952 lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00399 CAMK2D Pathway Commons Protein-Protein Interactions 1.0 null L-363 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.70867 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29409 BL588 (RCHY1) NURSA Protein Complexes 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null EW8 Achilles Cell Line Gene Essentiality Profiles 1.0 1.24238 migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.331025 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43771 PSMD1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-A87137733_GSK-690693_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MYO1F Pathway Commons Protein-Protein Interactions 1.0 null MYH9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZG-0008-SM-4E3J2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854037 18338247-SuppTable4B GeneSigDB Published Gene Signatures 1.0 null GTEX-OXRO-0011-R9A-SM-3NB1X GTEx Tissue Sample Gene Expression Profiles -1.0 -2.45279 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68688 GFPT2 Pathway Commons Protein-Protein Interactions 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.925641 nucleoid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.191456 CPSF6 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17993 RPS3 Pathway Commons Protein-Protein Interactions 1.0 null liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.631123 10-methoxyharmalan-5455 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PP-0926-SM-48TBZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.897775 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19912 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.33145 NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.33148 MKN45_STOMACH CCLE Cell Line Proteomics 1.0 2.86117 tRNA Aminoacylation Reactome Pathways 2014 1.0 null doxycycline_homo sapiens_gpl570_gse21912 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NRIP3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0104418 PLOD1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.947 PPAR direct repeat 1 MotifMap Predicted Transcription Factor Targets 1.0 null APOE Pathway Commons Protein-Protein Interactions 1.0 null outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896825 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null virion part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.1632 MYC_Activation - 8 hours_GDS2025_725_mouse_Pancreatic islet beta cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null meristem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.515317 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41202 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null BL1545 (TTK) NURSA Protein Complexes 1.0 null GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829038 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.858525 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222938 r7 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12892 TARS Pathway Commons Protein-Protein Interactions 1.0 null r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15847 imatinib_homo sapiens_gpl96_gds3047 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Obesity_Adipose tissue_GSE4692 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.50603 GTEX-NL3H-0011-R4a-SM-2I3GK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44 FOXP2 ChEA Transcription Factor Targets 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21036 YWHAZ Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11198 plumule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08514 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.363185 Cerebellum BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.983859 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923135 Perturb_8013_KD_Chd1_SRP090682 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.14062 ATL3 Pathway Commons Protein-Protein Interactions 1.0 null hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38624 regulation of biological process GO Biological Process Annotations 2015 1.0 null BXPC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null TUBB3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1793 metolazone-6292 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.82057 ADRBK2 Pathway Commons Protein-Protein Interactions 1.0 null NHLH1 JASPAR Predicted Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.921351 AGS Achilles Cell Line Gene Essentiality Profiles -1.0 -1.48901 OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.7335 F7 Pathway Commons Protein-Protein Interactions 1.0 null REST ENCODE Transcription Factor Targets 1.0 null ELMO2 Pathway Commons Protein-Protein Interactions 1.0 null SARS Pathway Commons Protein-Protein Interactions 1.0 null KP-N-RT-BM-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.19192 GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05426 RPL35 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.47388 GTEX-X4EP-0126-SM-3P5YV GTEx Tissue Sample Gene Expression Profiles 1.0 0.848986 Perturb_209_KO_Mki67_SRP295170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.42221 GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles 1.0 0.872551 BL2094 (MSH2) NURSA Protein Complexes 1.0 null TOV112D CCLE Cell Line Gene Expression Profiles 1.0 1.59549 pancreas_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.12095 TUHR14TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.37673 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06128 SND1 Pathway Commons Protein-Protein Interactions 1.0 null MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88202 CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23814 regulation of cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null BL1798 (BCL11B) NURSA Protein Complexes 1.0 null DDX39A Pathway Commons Protein-Protein Interactions 1.0 null CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null culture condition:cd8+ cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SUDHL6 CCLE Cell Line Gene Expression Profiles 1.0 1.81134 GTEX-QDT8-0011-R8A-SM-32PKE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904742 DLD1 BioGPS Cell Line Gene Expression Profiles 1.0 0.869382 BL1921 (KIAA1967) NURSA Protein Complexes 1.0 null Subiculum, ventral part, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34464 PPP2CB Pathway Commons Protein-Protein Interactions 1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974596 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22627 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27796 CTPS2 Pathway Commons Protein-Protein Interactions 1.0 null HSPD1 Pathway Commons Protein-Protein Interactions 1.0 null GBAS Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 15171711-Table1 GeneSigDB Published Gene Signatures 1.0 null deferasirox_homo sapiens_gpl570_gds3558 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16948 Glutathione S-transferase, C-terminal-like InterPro Predicted Protein Domain Annotations 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null reticulocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.800626 MBNL1 Pathway Commons Protein-Protein Interactions 1.0 null amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16821 TRAF6 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4314_KO_Hdac4_SRP219834 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.08173 PABPC1 Pathway Commons Protein-Protein Interactions 1.0 null VDAC2 Pathway Commons Protein-Protein Interactions 1.0 null GLRX3 Pathway Commons Protein-Protein Interactions 1.0 null r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38201 RPL10A Pathway Commons Protein-Protein Interactions 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.65855 Sloping Forehead DisGeNET Gene-Phenotype Associations 1.0 null NFIL3 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.68122 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.23831 GTEX-S7PM-0011-R6A-SM-3NM8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42751 EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -0.929871 hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.968198 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20519 SAMD4A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00676675 SLC25A1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.653 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null ETFA Pathway Commons Protein-Protein Interactions 1.0 null SLX1B Pathway Commons Protein-Protein Interactions 1.0 null KRT8 Pathway Commons Protein-Protein Interactions 1.0 null ACSM3 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DARS Pathway Commons Protein-Protein Interactions 1.0 null hematopoietic cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10386 BL1826 (TAOK3) NURSA Protein Complexes 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-0011-R1A-SM-4AT4C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2552 THPO LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00694345 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28357 a-FTO (78) (FTO) NURSA Protein Complexes 1.0 null heart valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.203275 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.33977 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840416 Anterolateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19359 SSRP1 Pathway Commons Protein-Protein Interactions 1.0 null leg muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.09659 ZMPSTE24 Pathway Commons Protein-Protein Interactions 1.0 null DDX1 Pathway Commons Protein-Protein Interactions 1.0 null RETSAT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00573021 Perturb_13318_KD_Gtf2i_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.88728 RPS6KA3 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_938_KO_Gcgr_SRP238015 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.48053 fenbendazole-2360 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cytosol COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94878 BRD-K59369769_tozasertib_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HELA Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.53831 Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20286 NPEPPS Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bupivacaine-5537 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 PRMT3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0067539 posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.864066 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.036015 CISD1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00554882 primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.934384 outer CP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.945576 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824055 SLIRP Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null FLI1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3133 meglumine-6445 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null roxithromycin-4778 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null butacaine-6225 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RPLP0 Pathway Commons Protein-Protein Interactions 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.853738 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.55863 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63976 ASXL1-24218140-BMDM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-137 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 Perturb_4293_KO_Tbc1d4_SRP374413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -19.5229 HNRNPM LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00571379 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.444884 BL1586 (EGFR) NURSA Protein Complexes 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Perturb_2959_Mut_H33A_SRP058766 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 KRT16 Pathway Commons Protein-Protein Interactions 1.0 null AM-38 GDSC Cell Line Gene Expression Profiles 1.0 1.57214 BRD-K49328571_dasatinib_HT29_24_h_0.37_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_9455_OE_Rnaseh1_SRP182028 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.32323 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923135 NCIH929_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 4.70296 BL5431 (ERCC5) NURSA Protein Complexes 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null OVCAR8 BioGPS Cell Line Gene Expression Profiles 1.0 1.32558 GTEX-RU72-0011-R9A-SM-2TF67 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54693 PRPF3 Pathway Commons Protein-Protein Interactions 1.0 null SNRNP200 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 2.20858 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A149-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD12 Pathway Commons Protein-Protein Interactions 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.585625 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14954 NEURL1B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0074697 inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916544 Edema CTD Gene-Disease Associations 1.0 1.49252 TBC1D15 Pathway Commons Protein-Protein Interactions 1.0 null SDHA Pathway Commons Protein-Protein Interactions 1.0 null EBNA1BP2 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8005-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MLLT4 Pathway Commons Protein-Protein Interactions 1.0 null Neurodevelopmental Disorder DisGeNET Gene-Disease Associations 1.0 null A549 BioGPS Cell Line Gene Expression Profiles -1.0 -1.34292 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.946619 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.963376 primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2959 ATP6V1B2 Pathway Commons Protein-Protein Interactions 1.0 null Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50559 DIAPH1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.07793 GTEX-TMMY-1126-SM-4DXSX GTEx Tissue Sample Gene Expression Profiles 1.0 1.39278 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37471 PPIL1 Pathway Commons Protein-Protein Interactions 1.0 null RPL26 Pathway Commons Protein-Protein Interactions 1.0 null SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20239 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.896594 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99231 parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66313 BL3348 (ATN1) NURSA Protein Complexes 1.0 null BT474 Achilles Cell Line Gene Essentiality Profiles -1.0 -2.03416 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31945 aminoacyl-trna ligase activity GO Molecular Function Annotations 2015 1.0 null Monocyte Count Procedure DisGeNET Gene-Phenotype Associations 1.0 null Perturb_14970_KD_Phf23_SRP248452 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.29578 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r4BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67065 GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3286 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43771 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.374993 GTEX-TSE9-0011-R9A-SM-3DB7Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17595 PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PPA2 Pathway Commons Protein-Protein Interactions 1.0 null TMPO Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.35294 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.551425 ASNS Pathway Commons Protein-Protein Interactions 1.0 null MOLM13 CCLE Cell Line Gene Expression Profiles 1.0 1.48505 H-EMC-SS Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.14246 PATU8988T CCLE Cell Line Gene Expression Profiles 1.0 1.42195 GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21201 SCYL1 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839132 PANC1005 Achilles Cell Line Gene Essentiality Profiles 1.0 1.20016 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.935285 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.434196 GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.3095 GTEX-SIU7-0426-SM-2XCDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864385 SUP-M2 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.86674 PABPC4 Pathway Commons Protein-Protein Interactions 1.0 null parasitic protozoa infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.700722 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null DOHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.880725 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null PI4KA Pathway Commons Protein-Protein Interactions 1.0 null SC-596 (CCNA2) NURSA Protein Complexes 1.0 null Perturb_2480_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cefapirin-3471 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null malaria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.673518 UBD LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00632742 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51252 OGDH Pathway Commons Protein-Protein Interactions 1.0 null valyl-tRNA aminoacylation GO Biological Process Annotations 2023 1.0 null POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gracile nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20078 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839132 REST JASPAR Predicted Transcription Factor Targets 1.0 null head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59387 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.65663 HSC4 CCLE Cell Line Gene Expression Profiles -1.0 -2.42346 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FUBP3 Pathway Commons Protein-Protein Interactions 1.0 null Aminoacyl-tRNA synthetase, class 1a, anticodon-binding InterPro Predicted Protein Domain Annotations 1.0 null Idiosyncratic drug effect_Hepatic Tissue_GSE2825 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.50807 Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMNA Pathway Commons Protein-Protein Interactions 1.0 null RH41_SOFT_TISSUE CCLE Cell Line Proteomics 1.0 2.42561 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.08638 liminal part of the r6 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1168 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0498 SAR1B Pathway Commons Protein-Protein Interactions 1.0 null Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14296 strophanthidin-7182 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ChIP_TCFCP2L1_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BL1936 (SMG5) NURSA Protein Complexes 1.0 null SAFB2 Pathway Commons Protein-Protein Interactions 1.0 null gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 HSP90AA1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00378352 CBC612 (RNF20) NURSA Protein Complexes 1.0 null RPL23 Pathway Commons Protein-Protein Interactions 1.0 null ATP5B Pathway Commons Protein-Protein Interactions 1.0 null SUCLG2 Pathway Commons Protein-Protein Interactions 1.0 null reticuloendothelial system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217346 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.51343 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38379 GTEX-NPJ8-0011-R4a-SM-2HML3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25118 UACC257 CCLE Cell Line Gene Expression Profiles 1.0 1.50835 HT1197_URINARY_TRACT CCLE Cell Line Proteomics 1.0 2.81233 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.67009 BL5398 (FAM175B) NURSA Protein Complexes 1.0 null female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93136 PDCD6 Pathway Commons Protein-Protein Interactions 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 MECP2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00485393 ATP1A1 Pathway Commons Protein-Protein Interactions 1.0 null GMPS Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4964_KO_WWOX_SRP277498 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.75462 UQCRC2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.84574 EFO21 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.03307 Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HADHB Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XV7Q-1626-SM-4BRWC GTEx Tissue Sample Gene Expression Profiles 1.0 0.825413 Lung adenocarcinoma_LUAD_TCGA-55-7283-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null aortic valve stenosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.393001 embryonic structure TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 TUBB4A Pathway Commons Protein-Protein Interactions 1.0 null X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2612 Cerebellar Atrophy DisGeNET Gene-Disease Associations 1.0 null lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.31319 Lung adenocarcinoma_LUAD_TCGA-44-6776-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null erythroid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.200047 MCC Pathway Commons Protein-Protein Interactions 1.0 null JHESOAD1 CCLE Cell Line Gene CNV Profiles 1.0 1.95836 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6646 K562 BioGPS Cell Line Gene Expression Profiles 1.0 0.907258 all GWASdb SNP-Phenotype Associations 1.0 0.035911 retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83575 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paragigantocellular reticular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48475 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.88591 IGHG1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14529_KO_Gata4/Nr5a2_SRP111204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.2972 MYC-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.61666 Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.0518 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39382 HEK 293 T-rex BioGPS Cell Line Gene Expression Profiles 1.0 1.24345 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WWYW-0011-R8A-SM-3NB3S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02496 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.049583 NCIH2081 CCLE Cell Line Gene Expression Profiles -1.0 -1.64026 WFS1_KO_GSE33372_395_mouse_hypothalamus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57005 LARP1 Pathway Commons Protein-Protein Interactions 1.0 null purine ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null Perturb_6237_KO_Setd1a_SRP365947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.13794 FBL Pathway Commons Protein-Protein Interactions 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_7999_KO_Wwtr1/Yap1_SRP265287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.15201 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50978 Perturb_7847_KD_PUM2_SRP166185 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.366 GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32662 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974596 Perturb_14506_OE_miR283p_SRP365438 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19545 Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC25A12 Pathway Commons Protein-Protein Interactions 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.16293 Brain_Hippocampus_Middle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.992934 Perturb_2484_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PSMD14 Pathway Commons Protein-Protein Interactions 1.0 null GATA1_G1E-ER4_mm9_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null Penis_Foreskin_Fibroblast_Primary_Cells_skin02 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.854767 MEIS1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-A28970875_PUROMYCIN HYDROCHLORIDE_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NCAPG Pathway Commons Protein-Protein Interactions 1.0 null cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.65689 RPS14 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14524_KO_LRHt_SRP009598 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.5759 NB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.32658 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.23207 ACTN1 Pathway Commons Protein-Protein Interactions 1.0 null ARG1 Pathway Commons Protein-Protein Interactions 1.0 null SGK1 Pathway Commons Protein-Protein Interactions 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.899456 SNU869 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.73675 GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.851462 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RELA JASPAR Predicted Transcription Factor Targets 1.0 null VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01133 DDX6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00591793 phagocytic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.133506 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.991837 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.973305 catalytic activity GO Molecular Function Annotations 2015 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02823 intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07117 HSPE1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-O5YT-0008-SM-4E3IQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.22494 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.862081 ZYX Pathway Commons Protein-Protein Interactions 1.0 null regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null FERMT3 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3259_KD_SUZ12_SRP044056 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SNU1033 CCLE Cell Line Gene CNV Profiles -1.0 -2.29857 yy1_20215434_hela_lof_human_gpl570_gds3788 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.854779 BL1870 (TRIP4) NURSA Protein Complexes 1.0 null exisulind-314 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GFM1 Pathway Commons Protein-Protein Interactions 1.0 null epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PFKP Pathway Commons Protein-Protein Interactions 1.0 null USP11 Pathway Commons Protein-Protein Interactions 1.0 null LDHA Pathway Commons Protein-Protein Interactions 1.0 null ITGB2 Pathway Commons Protein-Protein Interactions 1.0 null KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.408212 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.124347 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22013 dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1191 TP53 Pathway Commons Protein-Protein Interactions 1.0 null calycanthine-6221 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.98903 ANP32B Pathway Commons Protein-Protein Interactions 1.0 null DNAJC9 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043997 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.848111 EFTUD2 Pathway Commons Protein-Protein Interactions 1.0 null MEL-HO COSMIC Cell Line Gene Mutation Profiles 1.0 null BL991 (INCENP) NURSA Protein Complexes 1.0 null MFM-223 cell ProteomicsDB Cell Type and Tissue Protein Expression Profiles 1.0 0.976894 superficial stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72218 BL2293 (EDC4) NURSA Protein Complexes 1.0 null reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.85244 USF1 ENCODE Transcription Factor Targets 1.0 null Perturb_6343_KI_MCK_SRP353443 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 ICAM5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00561822 nordihydroguaiaretic acid-415 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.44855 CDC37 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OXRO-0011-R10A-SM-2I5EH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30371 IMMT Pathway Commons Protein-Protein Interactions 1.0 null Perturb_201_OE_Mir204_SRP131517 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.94442 ARF5 Pathway Commons Protein-Protein Interactions 1.0 null IPO7 Pathway Commons Protein-Protein Interactions 1.0 null MDN1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_80_KD_CENPA1_SRP187530 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.38858 AATF MSigDB Cancer Gene Co-expression Modules 1.0 null BRD-K08307026_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NCAPG LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00377142 SDCBP Pathway Commons Protein-Protein Interactions 1.0 null virion COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.161693 BTG2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00624479 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28347 placenta ProteomicsDB Cell Type and Tissue Protein Expression Profiles -1.0 -0.934797 nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045607 BL3118 (PPP4R2) NURSA Protein Complexes 1.0 null SNU840 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.55524 HS 675.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.01471 PPP2R2A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_7998_KO_Scrib/Taz/Yap1_SRP265287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.50603 chromoplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.688576 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0214 RPL23A Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.61933 Perturb_2960_Mut_H33A_SRP058766 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SK-N-DZ GDSC Cell Line Gene Expression Profiles 1.0 1.51717 Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acetohexamide-7482 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null posterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.62767 MAZ ENCODE Transcription Factor Targets 1.0 null Posterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55486 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8045 GSTP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_1361_KD_TRIM24_SRP331117 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PHF5A Pathway Commons Protein-Protein Interactions 1.0 null YWHAH Pathway Commons Protein-Protein Interactions 1.0 null TP53 JASPAR Predicted Transcription Factor Targets 1.0 null SNRPD2 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33513 skin TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 hsa-miR-615-3p MiRTarBase microRNA Targets 1.0 null GTEX-OOBJ-0326-SM-33HBO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916394 PRDM5 ChEA Transcription Factor Targets 1.0 null BPH-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.21183 golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6185 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45515 18818702-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null SLX4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4741 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.63234 HSD17B10 Pathway Commons Protein-Protein Interactions 1.0 null DYNC1H1 Pathway Commons Protein-Protein Interactions 1.0 null intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Perturb_14791_KD_SF3A2_SRP191866 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATP2B2 Pathway Commons Protein-Protein Interactions 1.0 null RPS26 Pathway Commons Protein-Protein Interactions 1.0 null KARS Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.991848 VIM Pathway Commons Protein-Protein Interactions 1.0 null HSPA5 Pathway Commons Protein-Protein Interactions 1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28667 PPP1CC Pathway Commons Protein-Protein Interactions 1.0 null PAICS Pathway Commons Protein-Protein Interactions 1.0 null Long Eyelashes DisGeNET Gene-Phenotype Associations 1.0 null GTEX-OHPN-0011-R1A-SM-2I5GB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14822 LARS Pathway Commons Protein-Protein Interactions 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null WDR48 Pathway Commons Protein-Protein Interactions 1.0 null COLO-704 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null EIF4A3 Pathway Commons Protein-Protein Interactions 1.0 null dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00548 neomycin-1383 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19265 Sarcoma_SARC_TCGA-3R-A8YX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76977 Acute Myeloid Leukemia_LAML_TCGA-AB-2856-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fetal Growth Retardation CTD Gene-Disease Associations 1.0 1.26825 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null normoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.200047 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRPD3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XMK1-0126-SM-4B65F GTEx Tissue Sample Gene Expression Profiles 1.0 1.0937 GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72978 AFG3L2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15645_KO_Tet2_SRP255385 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 NCIH2110 CCLE Cell Line Gene Expression Profiles -1.0 -1.99693 TMOD3_KO_GDS4827_418_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTSH Pathway Commons Protein-Protein Interactions 1.0 null SOX9 JASPAR Predicted Transcription Factor Targets 1.0 null Perturb_7297_KO_CD34_SRP156691 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.68579 H-89-6878 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL8796 (DAB2IP) NURSA Protein Complexes 1.0 null Perturb_7407_KD_HNRNPM_SRP010280 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.12109 CD24_Reduced expression_GDS1392_93_human_Bone Marrow GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ligase activity, forming carbon-oxygen bonds GO Molecular Function Annotations 2015 1.0 null IM95_STOMACH CCLE Cell Line Proteomics 1.0 2.07253 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.70339 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07405 H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null r10 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20005 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.06862 Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HK2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_9718_OE_Wt1_SRP126738 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.60492 BRD-A51777634_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02079 Perturb_1191_OE_CDYL_SRP335863 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STK4 Pathway Commons Protein-Protein Interactions 1.0 null SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.43526 OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13881 PPID Pathway Commons Protein-Protein Interactions 1.0 null TAL1_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBK-0126-SM-2YUND GTEx Tissue Sample Gene Expression Profiles 1.0 1.2319 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null scotoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.09419 20559987-TableS1 GeneSigDB Published Gene Signatures 1.0 null LYPLA2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 1.49695 SRSF6 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.70774 GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43657 ELAVL1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XV7Q-0426-SM-4BRVN GTEx Tissue Sample Gene Expression Profiles 1.0 0.95817 ethosuximide-1433 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.952972 IRGM LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00805202 Perturb_3292_KD_RORA_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GABRB2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00561479 17023574-TableS1 GeneSigDB Published Gene Signatures 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.99854 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.91506 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00756 ESYT2 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993987 GPX4 Pathway Commons Protein-Protein Interactions 1.0 null skmel30 HPA Cell Line Gene Expression Profiles -1.0 -1.17705 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.84576 LPCAT2 Pathway Commons Protein-Protein Interactions 1.0 null septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913463 KMO LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00686256 GTEX-XYKS-0005-SM-4BRUD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10332 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81686 IRF1 JASPAR Predicted Transcription Factor Targets 1.0 null RPMI-8866 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.826308 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.97042 hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061312 AARS Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -2.13751 FOXI1 JASPAR Predicted Transcription Factor Targets 1.0 null ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null arteriosclerotic cardiovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.21974 NF1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0071841 NDUFA5 Pathway Commons Protein-Protein Interactions 1.0 null Nucleus ambiguus, ventral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40546 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58274 UBTF ENCODE Transcription Factor Targets 1.0 null GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832847 5nM_dasatinib vs ctrl_K562 (Human) [19651622] SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs 1.0 null JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 3.26516 EP300 ENCODE Transcription Factor Targets 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82845 EMD Pathway Commons Protein-Protein Interactions 1.0 null SMC3-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236332 CACNA1S LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00863275 GM2345 BioGPS Cell Line Gene Expression Profiles -1.0 -1.47213 PSMC4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-O5YT-1726-SM-3NMD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.927442 PL4 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.54548 POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13357_KO_Ugcg_SRP352608 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Anterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05734 GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15048 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null ligase activity GO Molecular Function Annotations 2015 1.0 null GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60475 carpel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213833 MCC Hub Proteins Protein-Protein Interactions 1.0 null GTEX-P4PP-0326-SM-33HC4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27178 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.33737 SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SNRNP70 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A817-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMOD3_KO_GDS4827_415_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HES3_KD_GSE64449_187_mouse_Min6 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null YBX1 Pathway Commons Protein-Protein Interactions 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.20733 Leukemia_chronicMyelogenousK-562 BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.08144 HSP90AA4P Pathway Commons Protein-Protein Interactions 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.61685 PHGDH Pathway Commons Protein-Protein Interactions 1.0 null dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null pancreas HPA Tissue Gene Expression Profiles -1.0 -0.996392 HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.957161 Perturb_5432_KD_IGFBP3_SRP377970 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.3119 GTEX-NL4W-0011-R4a-SM-2I5GZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02587 SUN2 Pathway Commons Protein-Protein Interactions 1.0 null XRCC5 Pathway Commons Protein-Protein Interactions 1.0 null female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC7585053__F3 PFOCR Pathway Figure Associations 2023 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null leg TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083825 EIF4E Pathway Commons Protein-Protein Interactions 1.0 null LRRC8C Pathway Commons Protein-Protein Interactions 1.0 null lymph node HPA Tissue Protein Expression Profiles 1.0 1.25289 cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88001 PRKDC MSigDB Cancer Gene Co-expression Modules 1.0 null MEC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.33072 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21214 abnormality of the skeletal system GWASdb SNP-Phenotype Associations 1.0 0.143606 KYSE-520 GDSC Cell Line Gene Expression Profiles -1.0 -3.52935 stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.437205 purine nucleotide binding GO Molecular Function Annotations 2015 1.0 null Atherosclerosis_Aorta Smooth Muscle Tissue_GSE420 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -0.868716 BL3131 (PPP2CB) NURSA Protein Complexes 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.873877 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974596 HNRNPA3 Pathway Commons Protein-Protein Interactions 1.0 null PRDX2 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85464 GTEX-U8XE-0326-SM-3DB8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.24347 GTEX-WFG8-1626-SM-4LVMB GTEx Tissue Sample Gene Expression Profiles 1.0 0.885103 Micrognathism DisGeNET Gene-Disease Associations 1.0 null CSE1L Pathway Commons Protein-Protein Interactions 1.0 null KCTD12 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12060_KO|KO_Stat5a|Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 TCERG1 Pathway Commons Protein-Protein Interactions 1.0 null Anemia CTD Gene-Disease Associations 1.0 1.12703 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null BRD-K44432556_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HNRNPA0 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37925 food vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.41886 dactinomycin_mus musculus_gpl6246_gse21233 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7668 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 NELFA-20434984-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.918315 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.60396 MTOR_UP.N4.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null naproxen-1869 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.70503 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923135 H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.9186 GALK1 Pathway Commons Protein-Protein Interactions 1.0 null TECR Pathway Commons Protein-Protein Interactions 1.0 null RBBP4 Pathway Commons Protein-Protein Interactions 1.0 null RSV-A2_24Hour-KO_RSV_None_GSE18170 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.35237 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39309 CAPRIN1 Pathway Commons Protein-Protein Interactions 1.0 null NUP188 Pathway Commons Protein-Protein Interactions 1.0 null carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1354 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.948493 Perturb_13838_KO_Gpr124_ERP012531 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TERF2IP Pathway Commons Protein-Protein Interactions 1.0 null PPARG JASPAR Predicted Transcription Factor Targets 1.0 null JSC-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.81409 Perturb_9262_KO_Cdx2/Apc_SRP093647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.0452 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EPB41 Hub Proteins Protein-Protein Interactions 1.0 null TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null PCM1 Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25732 lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969316 GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71121 PSMC5 Pathway Commons Protein-Protein Interactions 1.0 null NDUFS3 Pathway Commons Protein-Protein Interactions 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -3.0847 Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35809 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSK3B_knockdown_202_GDS4305 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.67992 GTEX-R55D-1126-SM-48FEB GTEx Tissue Sample Gene Expression Profiles 1.0 0.898838 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10191 ISHIKAWA(HERAKLIO)02ER- COSMIC Cell Line Gene Mutation Profiles 1.0 null AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.826359 ETS1 ENCODE Transcription Factor Targets 1.0 null GTEX-X4XY-0226-SM-4E3IZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.892078 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null STAT1 JASPAR Predicted Transcription Factor Targets 1.0 null phenformin-4283 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prestwick-1083-6357 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80118 Global Developmental Delay DisGeNET Gene-Disease Associations 1.0 null rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47717 Perturb_14158_KO_UTX_SRP399588 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 KASUMI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21649 Perturb_13396_KD_HDAC1_SRP354102 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.78357 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12885 CBC551 (TACC3) NURSA Protein Complexes 1.0 null GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles 1.0 1.10053 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00756 GTEX-X88G-0326-SM-47JZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31728 intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06118 A704 CCLE Cell Line Gene Expression Profiles -1.0 -2.26689 CCT7 Pathway Commons Protein-Protein Interactions 1.0 null COASY Pathway Commons Protein-Protein Interactions 1.0 null brain GTEx Tissue Gene Expression Profiles -1.0 -1.42571 ATP1A4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-SNOS-1626-SM-3NMA4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05443 FOXO3 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A6UC-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC70 COSMIC Cell Line Gene Mutation Profiles 1.0 null pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23293 carbohydrate derivative binding GO Molecular Function Annotations 2015 1.0 null ikarugamycin-866 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null first GeneRIF Biological Term Annotations 1.0 null BL4396 (ARFGEF1) NURSA Protein Complexes 1.0 null C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH2 CCLE Cell Line Gene CNV Profiles 1.0 1.56374 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45417 NCR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00516191 Muscular Dystrophy_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE3252 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.8147 GTEX-UTHO-0011-R4A-SM-3GIJP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993483 Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIK3R2 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5537006__F1 PFOCR Pathway Figure Associations 2023 1.0 null ACTN2 Pathway Commons Protein-Protein Interactions 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08574 Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.49371 CAPZA1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NPJ7-0011-R1a-SM-3GACT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864284 Lung adenocarcinoma_LUAD_TCGA-MP-A4T8-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48178 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Blood Coagulation Disorders CTD Gene-Disease Associations 1.0 1.02262 cisplatin_homo sapiens_gpl570_gse23553 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-8116-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCRIB Pathway Commons Protein-Protein Interactions 1.0 null SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -2.10861 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.977061 NELFB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00508466 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59236 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-POMQ-0526-SM-3GADD GTEx Tissue Sample Gene Expression Profiles 1.0 0.979873 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3754 Perturb_3733_KO_Trp53_SRP296860 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.89342 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GATA1_G1E-ER4_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 NUDC Pathway Commons Protein-Protein Interactions 1.0 null 17660535-TableS4b GeneSigDB Published Gene Signatures 1.0 null SEC23B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.11031 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966579 layer I of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.888375 19286929-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04064 RPL19 Pathway Commons Protein-Protein Interactions 1.0 null ZFX-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.880356 HSC-2 GDSC Cell Line Gene Expression Profiles -1.0 -1.56442 TLX1::NFIC MotifMap Predicted Transcription Factor Targets 1.0 null regulation of cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null KRT77 Pathway Commons Protein-Protein Interactions 1.0 null SKOV3 BioGPS Cell Line Gene Expression Profiles -1.0 -1.25151 HT-144 GDSC Cell Line Gene Expression Profiles 1.0 1.55867 regulation of translational fidelity GO Biological Process Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRF JASPAR Predicted Transcription Factor Targets 1.0 null superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94507 LONP1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59361 inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.080706 USF2 ENCODE Transcription Factor Targets 1.0 null HIV encephalitis_frontal cortex_GSE3489 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.39541 mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94878 CBR1 Pathway Commons Protein-Protein Interactions 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3022 HNF4 MotifMap Predicted Transcription Factor Targets 1.0 null RPMI-8226 GDSC Cell Line Gene Expression Profiles 1.0 1.57178 UPF1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33368 Short Nose DisGeNET Gene-Phenotype Associations 1.0 null cyclopentolate-6214 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TUBB8 Pathway Commons Protein-Protein Interactions 1.0 null plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.995934 SYNCRIP Pathway Commons Protein-Protein Interactions 1.0 null CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900651 GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15756 Perturb_7283_KO_ACTC1_SRP060637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.71446 orchitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.748424 proxymetacaine-6492 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.48744 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24116 SRI Pathway Commons Protein-Protein Interactions 1.0 null plastid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.726599 USF2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1CB Pathway Commons Protein-Protein Interactions 1.0 null PTPN11 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles 1.0 1.26967 orbital frontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898173 COLO775 CCLE Cell Line Gene Expression Profiles 1.0 2.95588 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.79685 r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03415 atp binding GO Molecular Function Annotations 2015 1.0 null PLCG2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00545885 TOP1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSC3 CCLE Cell Line Gene CNV Profiles 1.0 1.37628 HK1 Pathway Commons Protein-Protein Interactions 1.0 null NCVADR RES BioGPS Cell Line Gene Expression Profiles 1.0 0.85691 carboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.18861 STOM Pathway Commons Protein-Protein Interactions 1.0 null Perturb_4711_KO_Sox9_ERP109172 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.75936 GTEX-R55G-0226-SM-48FEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.87492 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.39936 COPG1 Pathway Commons Protein-Protein Interactions 1.0 null MDA MB435 BioGPS Cell Line Gene Expression Profiles 1.0 1.09667 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05567 GTEX-VUSG-0726-SM-3GIK1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904315 SU-DHL-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null RBM3 Pathway Commons Protein-Protein Interactions 1.0 null SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09044 STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER ChEA Transcription Factor Targets 2022 1.0 null ovary TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CPT1A Pathway Commons Protein-Protein Interactions 1.0 null TAL1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null ONS-76 COSMIC Cell Line Gene Mutation Profiles 1.0 null TOP2A Pathway Commons Protein-Protein Interactions 1.0 null HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null NID1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00594954 QKI Pathway Commons Protein-Protein Interactions 1.0 null YWHAB Pathway Commons Protein-Protein Interactions 1.0 null EIF3F Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TET1-21490601-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null A3-KAW GDSC Cell Line Gene Expression Profiles 1.0 2.13076 testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 tiletamine-6516 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.90897 NAPA Pathway Commons Protein-Protein Interactions 1.0 null SUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Perturb_13450_KD_Hnrnpk_SRP146257 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.5128 GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11483 cellular aromatic compound metabolic process GO Biological Process Annotations 2015 1.0 null Depressed Nasal Bridge DisGeNET Gene-Phenotype Associations 1.0 null COUP-TF, HNF-4 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-VJYA-0126-SM-4KL1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.841231 ZNF354C JASPAR Predicted Transcription Factor Targets 1.0 null HSP90AB2P Pathway Commons Protein-Protein Interactions 1.0 null AKR1C3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00323513 18172295-SuppTable4 GeneSigDB Published Gene Signatures 1.0 null NDUFS2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SQSTM1 Pathway Commons Protein-Protein Interactions 1.0 null BL1789 (PAXIP1) NURSA Protein Complexes 1.0 null bethanechol-5539 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null imatinib_homo sapiens_gpl96_gds3043 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.918821 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04067 OPLAH Pathway Commons Protein-Protein Interactions 1.0 null UBR4 Pathway Commons Protein-Protein Interactions 1.0 null CRBN LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00360926 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null arthritis GWASdb SNP-Phenotype Associations 1.0 0.380651 NR2F1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K74710236_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955243 FOXD1 JASPAR Predicted Transcription Factor Targets 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20239 CLIC1 Pathway Commons Protein-Protein Interactions 1.0 null FLT4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0063263 CPSF7 Pathway Commons Protein-Protein Interactions 1.0 null vacuole LOCATE Predicted Protein Localization Annotations 1.0 null CHAGO-K-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-V955-0726-SM-3GAFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17736 GTEX-WYBS-1226-SM-3NM9N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.949257 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null HBZ Pathway Commons Protein-Protein Interactions 1.0 null RAPH1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00764499 GNAI3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.70758 A3-KAW Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.96667 VAPA Pathway Commons Protein-Protein Interactions 1.0 null spleen GTEx Tissue Gene Expression Profiles 1.0 1.07899 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null furan CTD Gene-Chemical Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO-684 COSMIC Cell Line Gene Mutation Profiles 1.0 null MTHFD1 Pathway Commons Protein-Protein Interactions 1.0 null lateral part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11771 CYCS Pathway Commons Protein-Protein Interactions 1.0 null RPA2 MSigDB Cancer Gene Co-expression Modules 1.0 null GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles 1.0 0.995564 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.976996 EKLF-21900194-ERYTHROCYTE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CACNA1A Pathway Commons Protein-Protein Interactions 1.0 null calculated GeneRIF Biological Term Annotations 1.0 null IDH1 Pathway Commons Protein-Protein Interactions 1.0 null imatinib_homo sapiens_gpl96_gds3049 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SATB1 mouse (SATB1) NURSA Protein Complexes 1.0 null PMC4955670__F5 PFOCR Pathway Figure Associations 2023 1.0 null testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BL695 (CC2D1A) NURSA Protein Complexes 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.982386 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09578 Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EED LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00678253 Rossmann-like alpha/beta/alpha sandwich fold InterPro Predicted Protein Domain Annotations 1.0 null VPS35 Pathway Commons Protein-Protein Interactions 1.0 null NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RU72-0926-SM-2TF6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.874764 dried cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.27605 PRKACB Pathway Commons Protein-Protein Interactions 1.0 null RPS18 Pathway Commons Protein-Protein Interactions 1.0 null valine-trna ligase activity GO Molecular Function Annotations 2015 1.0 null 697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 2.75261 Perturb_13169_KD_Ncor2_SRP060657 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -17.9393 SLC1A7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0039326 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CAT Pathway Commons Protein-Protein Interactions 1.0 null G120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 ALDH2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_17611_OE_U2AF35_SRP116787 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.62287 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839132 YD8 CCLE Cell Line Gene CNV Profiles -1.0 -1.5179 16498405-TableS10 GeneSigDB Published Gene Signatures 1.0 null PPAR, HNF-4, COUP, RAR MotifMap Predicted Transcription Factor Targets 1.0 null NDUFA2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00542023 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JJN-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC5081117__F6 PFOCR Pathway Figure Associations 2023 1.0 null PTGES3 Pathway Commons Protein-Protein Interactions 1.0 null HAT1 Pathway Commons Protein-Protein Interactions 1.0 null MAPRE1 Pathway Commons Protein-Protein Interactions 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Perturb_7284_KO_ACTC1_SRP060637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.54635 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ASPH LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00336795 lysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.103554 RAB10 Pathway Commons Protein-Protein Interactions 1.0 null parahippocampal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00057 TAGLN2 Pathway Commons Protein-Protein Interactions 1.0 null Diastolic Blood Pressure DisGeNET Gene-Phenotype Associations 1.0 null seedling TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.307167 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873871 AP2B1 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30271 RAD54L MSigDB Cancer Gene Co-expression Modules 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SURF4 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K08845546_FK506_HT115_6.0_h_22.2_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL2429 (NCOA4) NURSA Protein Complexes 1.0 null MDAMB134VI CCLE Cell Line Gene Expression Profiles -1.0 -1.6033 Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LANCL1 Pathway Commons Protein-Protein Interactions 1.0 null MCM5 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26697 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57054 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840416 intracellular part GO Cellular Component Annotations 2015 1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CDK2_knockdown_90_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.75513 CALU3 CCLE Cell Line Gene CNV Profiles 1.0 1.69968 Perturb_13443_KD_Taf2_SRP119047 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.90043 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.39967 UBA1 Pathway Commons Protein-Protein Interactions 1.0 null CSF1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00592112 Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null images GeneRIF Biological Term Annotations 1.0 null glis2_17618285_kidney_lof_mouse_gpl2897_gds2817 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.021421 HNRNPDL Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.8285 H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TIMM50 Pathway Commons Protein-Protein Interactions 1.0 null QARS Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03116 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92193 regulation of gene expression GO Biological Process Annotations 2015 1.0 null GTEX-OOBK-0526-SM-2HMJJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.31298 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.93769 Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver Neoplasms CTD Gene-Disease Associations 1.0 1.31446 GZMA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00548626 inner CP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21537 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Lung squamous cell carcinoma_LUSC_TCGA-58-A46J-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM28-19339689-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FOXA1 JASPAR Predicted Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.82669 BL4048 (USP32) NURSA Protein Complexes 1.0 null DDX18 Pathway Commons Protein-Protein Interactions 1.0 null Liver Diseases CTD Gene-Disease Associations 1.0 1.38584 bone marrow HPA Tissue Protein Expression Profiles -1.0 -1.26179 central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.824039 Perturb_9555_KO_Atg16l1_SRP159288 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -13.5082 SCH COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 SKMM2 Achilles Cell Line Gene Essentiality Profiles 1.0 1.1157 furosemide-4503 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ALDH18A1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K93747373_HG-5-113-01_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null epithelial cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_13343_KD_Snai1_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.39309 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A6ZA-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.86307 BL8110 (RAD54L2) NURSA Protein Complexes 1.0 null OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.56553 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.825485 TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.223906 head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.0876 r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12147 flumequine-1429 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SRPX Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37209 KAT2A ENCODE Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.52064 KLK3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00583381 MOGS Pathway Commons Protein-Protein Interactions 1.0 null SDF2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00695024 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37786 oxidoreductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.060037 BL8109 (RAD54L2) NURSA Protein Complexes 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL5428 (ERCC4) NURSA Protein Complexes 1.0 null MAX_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841409 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.976097 purine ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null EDC4 Pathway Commons Protein-Protein Interactions 1.0 null RPS20 Pathway Commons Protein-Protein Interactions 1.0 null JUND_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.00501 RPL11 Pathway Commons Protein-Protein Interactions 1.0 null orofacial cleft DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.249608 ALL-PO GDSC Cell Line Gene Expression Profiles 1.0 1.48606 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Small Anterior Fontanelle DisGeNET Gene-Phenotype Associations 1.0 null cefaclor-4967 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47194 regulation of biological quality GO Biological Process Annotations 2015 1.0 null KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.04487 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854758 UCK2 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.644 RANBP1 Pathway Commons Protein-Protein Interactions 1.0 null CCDC77 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00650506 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.29421 SMARCA4 Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_740_KD_KDM4A_SRP181840 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.51921 Microcephaly DisGeNET Gene-Disease Associations 1.0 null BL4783 (AKT1S1) NURSA Protein Complexes 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATG13 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35115 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24582 GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.926938 HMGA1 Pathway Commons Protein-Protein Interactions 1.0 null GSTK1 Pathway Commons Protein-Protein Interactions 1.0 null AN3CA CCLE Cell Line Gene Expression Profiles 1.0 1.5643 JJN3 CCLE Cell Line Gene Expression Profiles 1.0 2.73082 LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.826359 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.262986 abnormality of skeletal morphology GWASdb SNP-Phenotype Associations 1.0 0.16031 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 2.14076 TNFRSF10D Pathway Commons Protein-Protein Interactions 1.0 null a-CLSPN (CLSPN) NURSA Protein Complexes 1.0 null brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 imatinib_homo sapiens_gpl96_gds3042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PRKACA Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SELL LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00400455 PHB MSigDB Cancer Gene Co-expression Modules 1.0 null striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.891004 learning disability DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.694301 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.950462 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841019 USP46 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909867 KPNB1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_10147_KO_FAM122A_SRP235545 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CTCF ENCODE Transcription Factor Targets 1.0 null telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-WL46-0926-SM-3LK7T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843195 KRT19 Pathway Commons Protein-Protein Interactions 1.0 null RPL15 Pathway Commons Protein-Protein Interactions 1.0 null plastid part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.058465 EPS15 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.72132 Perturb_728_OE_QKI5_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 MYO1E Pathway Commons Protein-Protein Interactions 1.0 null tRNA charging HumanCyc Pathways 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51509 EEF1D Pathway Commons Protein-Protein Interactions 1.0 null SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5558 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51252 TRIP13 Pathway Commons Protein-Protein Interactions 1.0 null Ectorhinal area/Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.10462 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51509 ACAT1 Pathway Commons Protein-Protein Interactions 1.0 null OMC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL3114 (PPP4R1) NURSA Protein Complexes 1.0 null MRPS23 Pathway Commons Protein-Protein Interactions 1.0 null VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.82415 PCM6 CCLE Cell Line Gene Expression Profiles 1.0 1.45422 Perturb_5325_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.48946 EP300_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.202403 Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28947 FLNB Pathway Commons Protein-Protein Interactions 1.0 null PARP1 Pathway Commons Protein-Protein Interactions 1.0 null A549_LUNG CCLE Cell Line Proteomics 1.0 2.23061 CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_8831_KD_S100A16_SRP313537 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21176 IGF2BP2 Pathway Commons Protein-Protein Interactions 1.0 null IPO5 Pathway Commons Protein-Protein Interactions 1.0 null BCLAF1_02_142 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.64193 HNRNPK Pathway Commons Protein-Protein Interactions 1.0 null sporulating cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03741 Proteinuria CTD Gene-Disease Associations 1.0 1.26021 GTEX-XGQ4-1526-SM-4AT6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.857302 HNRNPH1 Pathway Commons Protein-Protein Interactions 1.0 null LSM3 Pathway Commons Protein-Protein Interactions 1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.954436 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14749 SLC25A5 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64608 PHACTR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00582923 aminoacyl-trna editing activity GO Molecular Function Annotations 2015 1.0 null GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.68272 PUM1 Pathway Commons Protein-Protein Interactions 1.0 null E2F4_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11715_KO_Tgfbr2_SRP105112 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.35411 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37521 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K74710236_VU0410183-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-T5JC-0011-R9A-SM-32PLV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844871 GTEX-RVPU-0011-R3A-SM-2XCAE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1696 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48377 CLTA Pathway Commons Protein-Protein Interactions 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.924746 KE-37 COSMIC Cell Line Gene Mutation Profiles 1.0 null olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33169 PBX1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K61323504_sb 225002_A375_24.0_h_11.1_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HT55 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.35502 anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.986165 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02112 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03229 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32319 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.871695 HEATR3 Pathway Commons Protein-Protein Interactions 1.0 null LITAF LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00739047 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00447 NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null organelle inner membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.241356 erythroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.200047 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.90787 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45588 SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IDH2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QDT8-0011-R5A-SM-32PKN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18944 Protozoan Infection_Intestinal Epithelium_GSE2077 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.63533 Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL1691 (MAD1L1) NURSA Protein Complexes 1.0 null FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_16917_KD_Maf1_SRP375944 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.64564 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.70811 BL1966 (RANBP1) NURSA Protein Complexes 1.0 null FOLH1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00616663 Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.53332 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.902102 heterocycle metabolic process GO Biological Process Annotations 2015 1.0 null TMOD3_KO_GDS4827_39_mouse_fetal liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ITGA5 Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.961066 outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04447 ELK1 JASPAR Predicted Transcription Factor Targets 1.0 null CCL22 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00462559 HSP90AA2 Pathway Commons Protein-Protein Interactions 1.0 null ACO2 Pathway Commons Protein-Protein Interactions 1.0 null MDAMB231 CCLE Cell Line Gene CNV Profiles 1.0 1.40381 r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1844 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28212 SU-DHL-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.51002 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21405 Amino Acid metabolism(Mus musculus) WikiPathways Pathways 2014 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS 255.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.862994 RPS28 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8456_KO_FGFR3/FGFR4_SRP386785 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.86373 NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null UBTF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRAF6 Hub Proteins Protein-Protein Interactions 1.0 null CD105+_Endothelial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.24057 Perturb_205_KD_Robo1/Id1/ld3_SRP193147 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.70668 Glutathione S-transferase, C-terminal InterPro Predicted Protein Domain Annotations 1.0 null pregnenolone-4802 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null sisomicin-4014 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL7129 (CCDC124) NURSA Protein Complexes 1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.14474 YLPM1 Pathway Commons Protein-Protein Interactions 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null SR-95639A-1336 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-WEY5-0226-SM-3GIKN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864274 Perturb_5472_KD_Ptbp1_SRP265083 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.71326 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.926252 TFF2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00597599 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3184 epithelioma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_8385_KD_USP22_SRP213120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.9565 calfactant CTD Gene-Chemical Interactions 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.929514 BRD-K89093471_VU0418934-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.20463 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02572 FAM105A Pathway Commons Protein-Protein Interactions 1.0 null substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14188 hydroflumethiazide-7259 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.27794 SRPR Pathway Commons Protein-Protein Interactions 1.0 null MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null muscular system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992147 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL8517 (CKAP2L) NURSA Protein Complexes 1.0 null HSPB1 Pathway Commons Protein-Protein Interactions 1.0 null MM1S Achilles Cell Line Gene Essentiality Profiles 1.0 1.42162 sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.02266 BL7067 (IKBKB) NURSA Protein Complexes 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840416 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null RERF-LC-KJ COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 3.46129 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypoplasia DisGeNET Gene-Disease Associations 1.0 null GTEX-QV31-0126-SM-447BP GTEx Tissue Sample Gene Expression Profiles 1.0 0.950548 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20792 GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90609 Perturb_5331_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.83288 TRIM28 Pathway Commons Protein-Protein Interactions 1.0 null EM-2 GDSC Cell Line Gene Expression Profiles 1.0 1.5667 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18929 SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.78454 SLC18A3_KD_GDS4325_618_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null digestive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MXI1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04024 GFI1B-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null bezafibrate-1275 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Profound Intellectual Disabilities DisGeNET Gene-Disease Associations 1.0 null TFCP2L1 ChEA Transcription Factor Targets 1.0 null ILKAP Pathway Commons Protein-Protein Interactions 1.0 null RPMI-8402 COSMIC Cell Line Gene Mutation Profiles 1.0 null BL7244 (MAST4) NURSA Protein Complexes 1.0 null PSMA1 Pathway Commons Protein-Protein Interactions 1.0 null nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null TBX5-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ENC1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.007283 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89402 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.71501 ADAMTSL4 Pathway Commons Protein-Protein Interactions 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.937381 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.77174 sirolimus-402 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CLCNKA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00580459 COUP direct repeat 1 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5425-01A-02R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SBC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null PDHB Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VCP Pathway Commons Protein-Protein Interactions 1.0 null RPL30 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XV7Q-0826-SM-4BRV7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.833973 EIF4A2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26623 OLA1 Pathway Commons Protein-Protein Interactions 1.0 null adenyl nucleotide binding GO Molecular Function Annotations 2015 1.0 null RAC1 Pathway Commons Protein-Protein Interactions 1.0 null muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.329361 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.466928 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00909 DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_14013_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 OBSL1 Pathway Commons Protein-Protein Interactions 1.0 null lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832792 15474998-tableS1b GeneSigDB Published Gene Signatures 1.0 null u26684 HPA Cell Line Gene Expression Profiles 1.0 0.989644 rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.174018 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ESD Pathway Commons Protein-Protein Interactions 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43623 appendix HPA Tissue Gene Expression Profiles 1.0 0.938065 Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null etioplast prolamellar body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.749546 RPL31 Pathway Commons Protein-Protein Interactions 1.0 null KIF5B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.42749 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.589234 mRNA_PRDM14_20953172 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84759 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04771 PCBP2 Pathway Commons Protein-Protein Interactions 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11691 OV-17R Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.49926 CPCN CCLE Cell Line Gene CNV Profiles 1.0 1.64619 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.6084 esculin-6310 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null vitamin c_mus musculus_gpl1261_gse37676 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KTN1 Pathway Commons Protein-Protein Interactions 1.0 null BMI1 MSigDB Cancer Gene Co-expression Modules 1.0 null HCC1143 CCLE Cell Line Gene CNV Profiles 1.0 1.37628 MEIS1 ChEA Transcription Factor Targets 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.951657 GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.65262 GTEX-NPJ8-0011-R2a-SM-2TC6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18036 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39161 GTEX-R53T-0005-SM-3GADK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23131 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69414 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.053463 POLR2AphosphoS5_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905639 DBN1 Pathway Commons Protein-Protein Interactions 1.0 null ANKRD17 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPAB Pathway Commons Protein-Protein Interactions 1.0 null CTSB Pathway Commons Protein-Protein Interactions 1.0 null KNTC1 Pathway Commons Protein-Protein Interactions 1.0 null organonitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null mantle zone of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11771 TBP ENCODE Transcription Factor Targets 1.0 null BRD-K31342827_GF-109203X_VCAP_6.0_h_12.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28687 18757322-TableS1 GeneSigDB Published Gene Signatures 1.0 null organic cyclic compound metabolic process GO Biological Process Annotations 2015 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22627 MYOD1_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KHM1B CCLE Cell Line Gene Expression Profiles 1.0 1.40788 COPG2 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05127 r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06021 internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 ChIP_ZFX_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null cisplatin_mus musculus_gpl339_gse6206 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-Q2AH-0008-SM-48U2J GTEx Tissue Sample Gene Expression Profiles 1.0 0.977483 BL2995 (CRTC2) NURSA Protein Complexes 1.0 null PMC3469658__F3 PFOCR Pathway Figure Associations 2023 1.0 null Ectorhinal area/Layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56616 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.967758 GTEX-P4PP-0008-SM-48TDV GTEx Tissue Sample Gene Expression Profiles 1.0 1.18806 GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41643 r7 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07883 DNAJA1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-Q2AH-1926-SM-2S1PN GTEx Tissue Sample Gene Expression Profiles 1.0 0.948514 alverine-1426 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 heart GTEx Tissue Gene Expression Profiles -1.0 -1.10872 BL2777 (NF2) NURSA Protein Complexes 1.0 null TUBB1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.27965 GNAO1 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCND2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0066062 hsa-let-7e-5p MiRTarBase microRNA Targets 1.0 null SLC7A5 Pathway Commons Protein-Protein Interactions 1.0 null YWHAZ Hub Proteins Protein-Protein Interactions 1.0 null CHAGOK1 CCLE Cell Line Gene Expression Profiles -1.0 -2.16712 GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10316 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.95638 CBC542 (CYLD) NURSA Protein Complexes 1.0 null BRD-K31542390_Mycophenolic acid_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MYC_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAL1 ChEA Transcription Factor Targets 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.94523 GTEX-RUSQ-0826-SM-47JWW GTEx Tissue Sample Gene Expression Profiles 1.0 1.2255 SKCO1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.2675 POLR2AphosphoS5_G1E-ER4_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PRKDC Pathway Commons Protein-Protein Interactions 1.0 null pararosaniline-893 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null trichlormethiazide-4783 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null mitochondrion GO Cellular Component Annotations 2015 1.0 null HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11109 EEF1A1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BAG5 Pathway Commons Protein-Protein Interactions 1.0 null Posterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55201 LONRF2 Pathway Commons Protein-Protein Interactions 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46889 Perturb_8454_OE_MT1G_SRP352861 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.73608 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.909018 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00782 periventricular stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4661 GTEX-Q2AG-0011-R9A-SM-2HMJ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38665 GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles 1.0 1.21108 Depression_Cerebral cortex_GSE12654 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.47784 b-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.92777 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47779 SUMO2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00691 Anterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24282 ARCN1 Pathway Commons Protein-Protein Interactions 1.0 null IKBKB Pathway Commons Protein-Protein Interactions 1.0 null outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.890921 GTEX-WQUQ-0426-SM-3MJFU GTEx Tissue Sample Gene Expression Profiles 1.0 0.830061 HNF4 direct repeat 1 MotifMap Predicted Transcription Factor Targets 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47004 Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.08655 kaposi's sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.312827 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.873718 BL3283 (C7orf27) NURSA Protein Complexes 1.0 null AKR7A2 Pathway Commons Protein-Protein Interactions 1.0 null CCT6A Pathway Commons Protein-Protein Interactions 1.0 null TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20029 GTEX-WVLH-0011-R7A-SM-3MJFB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01595 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SL-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.299452 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.15695 BRD-K28120222_Prestw-550_HEPG2_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null idoxuridine-4785 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL6649 (GRB10) NURSA Protein Complexes 1.0 null RPL7A Pathway Commons Protein-Protein Interactions 1.0 null GUCY2D LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00658696 RPS6 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GO-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K24132293_piperlongumine (HPLC)_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_1490_KO_Rpl23a_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.88243 Perturb_6164_KO_Tet2_SRP060364 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.44809 Perturb_7330_KO_CD34_SRP156691 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.64612 YARS Pathway Commons Protein-Protein Interactions 1.0 null indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46481 duodenum HPA Tissue Protein Expression Profiles 1.0 1.25289 ESR1 JASPAR Predicted Transcription Factor Targets 1.0 null Cerebral Cortical Atrophy DisGeNET Gene-Disease Associations 1.0 null RFC4 Pathway Commons Protein-Protein Interactions 1.0 null IKBIP Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26862 MYBL2 ChEA Transcription Factor Targets 1.0 null RSL1D1 Pathway Commons Protein-Protein Interactions 1.0 null 18400362-Figure1a GeneSigDB Published Gene Signatures 1.0 null BL409 (UPF1) NURSA Protein Complexes 1.0 null monastrol-311 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null quercetin-917 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SMC3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826766 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02262 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null RPS14_DN.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null MAP4 Pathway Commons Protein-Protein Interactions 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15754 BL2640 (TERF2) NURSA Protein Complexes 1.0 null SC-48788 (FOXG1) NURSA Protein Complexes 1.0 null CAPN2 Pathway Commons Protein-Protein Interactions 1.0 null GYS1 Pathway Commons Protein-Protein Interactions 1.0 null MRPL43 Pathway Commons Protein-Protein Interactions 1.0 null EPN1 Pathway Commons Protein-Protein Interactions 1.0 null medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06213 MS4A10 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00511665 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.863712 pancreas HPA Tissue Protein Expression Profiles 1.0 1.25289 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.952792 GTEX-QLQW-0126-SM-447BK GTEx Tissue Sample Gene Expression Profiles 1.0 1.18748 TPP1 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 heart_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.20664 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0212 STAT5A ChEA Transcription Factor Targets 1.0 null DNM1L Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12537_KO_Pkd1_SRP388451 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.75235 PGAM5 Pathway Commons Protein-Protein Interactions 1.0 null NCIH1092 CCLE Cell Line Gene CNV Profiles -1.0 -1.60803 Infertility, Male CTD Gene-Disease Associations 1.0 1.34285 CARD9 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.998415 BICR56 CCLE Cell Line Gene Expression Profiles -1.0 -1.77656 SETDB1-19884255-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EKVX GDSC Cell Line Gene Expression Profiles -1.0 -1.56172 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.631598 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33744 DYNC1LI2 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMWD Pathway Commons Protein-Protein Interactions 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02918 ATXN2L Pathway Commons Protein-Protein Interactions 1.0 null interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03795 PTBP1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S7SF-0426-SM-3K2B7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1346 MAF-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PANC1_PANCREAS CCLE Cell Line Proteomics 1.0 2.23061 Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF3K Pathway Commons Protein-Protein Interactions 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.179802 Gene Expression Reactome Pathways 2014 1.0 null TNPO1 Pathway Commons Protein-Protein Interactions 1.0 null ncrna metabolic process GO Biological Process Annotations 2015 1.0 null TAL1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXF2 JASPAR Predicted Transcription Factor Targets 1.0 null CUL4B Pathway Commons Protein-Protein Interactions 1.0 null SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pivmecillinam-7312 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37471 JUND Pathway Commons Protein-Protein Interactions 1.0 null MAPK1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_81_KD_CENPA1_SRP187530 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.61188 primary auditory cortex (core)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.934528 DNAJA2 Pathway Commons Protein-Protein Interactions 1.0 null amygdaloid complex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17704 CNOT3-19339689-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SW837 CCLE Cell Line Gene Expression Profiles -1.0 -1.85229 lateral part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64611 GM2493 BioGPS Cell Line Gene Expression Profiles -1.0 -2.53068 NACA Pathway Commons Protein-Protein Interactions 1.0 null ASXL1 ChEA Transcription Factor Targets 1.0 null BL3032 (ERBB2) NURSA Protein Complexes 1.0 null PTK2B Pathway Commons Protein-Protein Interactions 1.0 null ATP2B3 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP2-23625967-PFSK-1 AND SK-N-MC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null AQP2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00708089 tolfenamic acid-1437 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.968768 HLA-B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35175 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.1847 GTEX-WFON-0226-SM-3GIKR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.887589 NOMO1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0922 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.69647 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00133 MAMSTR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00537327 MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63868 carboxylic ester hydrolase activity GO Molecular Function Annotations 2015 1.0 null BL4805 (UBE4B) NURSA Protein Complexes 1.0 null GTEX-QVUS-0011-R9A-SM-3GIJA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864755 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.827035 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null TCF3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -1.03115 HCC4006 CCLE Cell Line Gene CNV Profiles -1.0 -2.18642 GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72811 Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZMIZ1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYL6 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4648 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.891251 TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.881846 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.83804 NKX3-1 JASPAR Predicted Transcription Factor Targets 1.0 null CSTF3 Pathway Commons Protein-Protein Interactions 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00318 SHC1 Pathway Commons Protein-Protein Interactions 1.0 null endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21807 CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23947 eye TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 pyrvinium-6339 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Monocyte Count Result DisGeNET Gene-Phenotype Associations 1.0 null Subiculum, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12583 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.249329 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59216 valine leucine and isoleucine biosynthesis KEGG Pathways 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.17932 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 2.00954 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.63648 GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07612 Parasubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07976 NUP210 Pathway Commons Protein-Protein Interactions 1.0 null Hepatitis CTD Gene-Disease Associations 1.0 1.06552 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.860652 NCSTN Pathway Commons Protein-Protein Interactions 1.0 null erythrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.498048 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24123 SLC3A2 Pathway Commons Protein-Protein Interactions 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.199 GTEX-OOBK-2626-SM-2HMKY GTEx Tissue Sample Gene Expression Profiles 1.0 0.907212 embryo TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.25455 oxoacid metabolic process GO Biological Process Annotations 2015 1.0 null NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null CBC2032 (ZMYND8) NURSA Protein Complexes 1.0 null PSMC6 Pathway Commons Protein-Protein Interactions 1.0 null Primary somatosensory area, mouth, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36563 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00227 Seizures DisGeNET Gene-Phenotype Associations 1.0 null metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065876 UBAP2L Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QDT8-0011-R1A-SM-32PKS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988072 HNRNPA2B1 Pathway Commons Protein-Protein Interactions 1.0 null NSF Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55303 GTEX-OHPN-0011-R2A-SM-2I5FB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41218 GTEX-N7MS-1626-SM-3LK5F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.96006 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 2.14505 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38284 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54102 FUS Pathway Commons Protein-Protein Interactions 1.0 null NCI-H82 GDSC Cell Line Gene Expression Profiles 1.0 2.30103 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles 1.0 1.19413 4h_cisplatin vs ctrl_mESC (Mouse) [22006019] SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs 1.0 null Perturb_15981_KO_Ewsr1_SRP164692 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.0985 Osteolysis_Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)_GSE755 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.49247 ACOT8 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fluticasone-4011 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RPS2 Pathway Commons Protein-Protein Interactions 1.0 null MYOD1 ENCODE Transcription Factor Targets 1.0 null XRCC6 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QDVJ-0926-SM-2I5FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.01669 CLECL1P LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00609663 ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.928959 MYC ChEA Transcription Factor Targets 1.0 null NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null SYK_knockdown_191_GSE54065 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.68613 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_12504_KD_BCDIN3D_SRP285644 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.13247 GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.895323 ERLIN2 Pathway Commons Protein-Protein Interactions 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825548 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 AM38 Achilles Cell Line Gene Essentiality Profiles 1.0 1.08886 BL1657 (SMG1) NURSA Protein Complexes 1.0 null alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053502 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52095 GTEX-RU72-0011-R7A-SM-2TF5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06916 wing TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.428401 CSNK2B Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25037 GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11316 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.60485 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923135 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.72258 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.62802 GTF2B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.28281 cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900651 GNB2L1 Pathway Commons Protein-Protein Interactions 1.0 null DHX16 Pathway Commons Protein-Protein Interactions 1.0 null BL6127 (OXSR1) NURSA Protein Complexes 1.0 null BL8483 (AAK1) NURSA Protein Complexes 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null klf4_17017123_rko_gof_human_gpl96_gds1942 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.34609 ANXA9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0078695 Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hydrolase activity GO Molecular Function Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4733_KO_Firre_SRP119182 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.0753 sporozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.145339 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14175 RGS14 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00568106 Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25121 OMC-1 GDSC Cell Line Gene Expression Profiles -1.0 -2.06387 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05169 ATG4B Pathway Commons Protein-Protein Interactions 1.0 null ABCE1 Pathway Commons Protein-Protein Interactions 1.0 null central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 HCC1833_LUNG CCLE Cell Line Proteomics 1.0 2.13898 SNU1_STOMACH CCLE Cell Line Proteomics 1.0 10.4844 adenyl ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null GTEX-POMQ-0126-SM-48TD6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07627 TRIM28_02_63 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59018 GTEX-T6MN-0126-SM-32PLP GTEx Tissue Sample Gene Expression Profiles 1.0 0.84329 PRDM5-23873026-MEF-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles 1.0 1.05242 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25918 GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles 1.0 1.29844 Abnormalities, Drug-Induced CTD Gene-Disease Associations 1.0 1.5186 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1527 GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44492 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.81001 organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.157218 arsenic trioxide_homo sapiens_gpl201_gse48441 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NANOG-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CAPZB Pathway Commons Protein-Protein Interactions 1.0 null head of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.71106 estradiol_homo sapiens_gpl570_gse23610 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.21009 biological regulation GO Biological Process Annotations 2015 1.0 null OCUM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null OAT Pathway Commons Protein-Protein Interactions 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.1525 GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877903 lateral ventricle HPA Tissue Protein Expression Profiles 1.0 0.706445 GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles 1.0 1.12105 RAN Pathway Commons Protein-Protein Interactions 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.55476 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98224 MYBBP1A Pathway Commons Protein-Protein Interactions 1.0 null TLR5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00489213 mitochondrion COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.41182 GTEX-NL3G-0008-SM-4E3JX GTEx Tissue Sample Gene Expression Profiles 1.0 1.03922 PRPF8 Pathway Commons Protein-Protein Interactions 1.0 null mitochondrial inner membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.25438 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.665514 H3K36me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARHGAP4 Pathway Commons Protein-Protein Interactions 1.0 null obtained GeneRIF Biological Term Annotations 1.0 null BRD-K28143534_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K79090631_CGP-60474_PC3_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09931 IST1 Pathway Commons Protein-Protein Interactions 1.0 null seed TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31187 Perturb_9001_KD_KAT7_SRP174052 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.39889 Transplanted Heart Complication_Myocardial tissue_GSE582 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.36004 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01569 KIF5A Pathway Commons Protein-Protein Interactions 1.0 null meticrane-7282 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PAK3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00490644 CSDE1 Pathway Commons Protein-Protein Interactions 1.0 null A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38335 GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40958 SF172 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.44865 TRIM69 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00556895 GTEX-X3Y1-0426-SM-3P5Z4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839126 BL2379 (RFWD3) NURSA Protein Complexes 1.0 null CRKL Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-0426-SM-3GIKT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833607 Prestwick-1080-4354 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CSNK1A1 Pathway Commons Protein-Protein Interactions 1.0 null PPP2R1A Pathway Commons Protein-Protein Interactions 1.0 null USF2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01277 cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054261 GTEX-XYKS-1726-SM-4E3IO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09137 TMEM160 Pathway Commons Protein-Protein Interactions 1.0 null L-Valine DrugBank Drug Targets 1.0 null Perturb_13142_KO_Ngly1_SRP166093 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.1473 PPP1CA Pathway Commons Protein-Protein Interactions 1.0 null HIST1H4F Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11988 Perturb_8694_KO_METTL1_SRP314965 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.988029 IKBKG Hub Proteins Protein-Protein Interactions 1.0 null lysosome LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H1563 COSMIC Cell Line Gene Mutation Profiles 1.0 null TLR3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00571196 nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 RBM10 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00724209 Frontal pole, cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34227 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QX-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null COLGALT1 Pathway Commons Protein-Protein Interactions 1.0 null CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839132 ANXA3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00326421 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.62702 HSPA9 Pathway Commons Protein-Protein Interactions 1.0 null TACR3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00490411 atherosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.22145 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17511 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Generalized Hypotonia DisGeNET Gene-Phenotype Associations 1.0 null Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COPB1 Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-361 COSMIC Cell Line Gene Mutation Profiles 1.0 null znf263_19887448_helas3_lof_human_gpl6884_gse19146 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.005759 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.70692 SKIV2L2 Pathway Commons Protein-Protein Interactions 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3754 ASXL1-24218140-BMDM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0011-R9A-SM-4GICI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20671 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.825187 BHLHE40 ENCODE Transcription Factor Targets 1.0 null SF3B3 Pathway Commons Protein-Protein Interactions 1.0 null secondary lysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.133506 LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13452 GTEX-XLM4-0004-SM-4AT5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.08202 Perturb_17423_KO_Cic_SRP126501 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.55602 ZNF391 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00858999 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 BL119 (ATR) NURSA Protein Complexes 1.0 null SNU1214 CCLE Cell Line Gene CNV Profiles -1.0 -1.91983 GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles 1.0 1.05203 DNM1 Pathway Commons Protein-Protein Interactions 1.0 null EEF1G Pathway Commons Protein-Protein Interactions 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.234302 Perturb_5335_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.05518 regulation of protein metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-RVPV-0008-SM-47JYW GTEx Tissue Sample Gene Expression Profiles 1.0 1.22968 leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086806 GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30547 GTEX-QLQW-0226-SM-447BJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.06585 BL5855 (CDCA3) NURSA Protein Complexes 1.0 null SPIB JASPAR Predicted Transcription Factor Targets 1.0 null outer CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928206 benzydamine-7169 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null EDD_DEPLETION_GDS2445_116_human_embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MAPKAPK3 Pathway Commons Protein-Protein Interactions 1.0 null Aorta Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.889576 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938753 PIAS1_Depletion_GDS5076_12_human_MDA-MB 231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14824 Trolox C-7304 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ABCD1 Pathway Commons Protein-Protein Interactions 1.0 null MFE-280 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.71707 digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 estradiol_mus musculus_gpl81_gse1839 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-S7PM-0011-R5A-SM-3NM8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57137 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12956 CHMP2A Pathway Commons Protein-Protein Interactions 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.72176 gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 ACTR2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1909 BL2779 (SUV39H1) NURSA Protein Complexes 1.0 null vein disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.335046 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null EM2 CCLE Cell Line Gene CNV Profiles 1.0 2.09723 DDB1 Pathway Commons Protein-Protein Interactions 1.0 null PRKCD Pathway Commons Protein-Protein Interactions 1.0 null G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null AK2 Pathway Commons Protein-Protein Interactions 1.0 null deferoxamine-573 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL2389 (CUL4A) NURSA Protein Complexes 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.644858 rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.0553 Temporal association areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65637 SIN3A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ribonucleoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.760433 INTS1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00700241 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null KLF1 ChEA Transcription Factor Targets 1.0 null PC-3_[JPC-3] COSMIC Cell Line Gene Mutation Profiles 1.0 null reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02627 N-acetylmuramic acid-3262 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null r4 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67173 HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell culture TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CAOV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.94839 nadh dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.180045 Lung adenocarcinoma_LUAD_TCGA-97-8179-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNRNPD Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 2.28126 PPA1 Pathway Commons Protein-Protein Interactions 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.908588 plant reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094418 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044893 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.905237 Lupus Erythematosus, Systemic HuGE Navigator Gene-Phenotype Associations 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81454 Perturb_13441_KD_Tada1_SRP119047 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.13472 Temporal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64122 CP in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.108 GRB2 Pathway Commons Protein-Protein Interactions 1.0 null EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRD1 Pathway Commons Protein-Protein Interactions 1.0 null RCC1 Pathway Commons Protein-Protein Interactions 1.0 null Bach1 MotifMap Predicted Transcription Factor Targets 1.0 null viral envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.271533 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SH3BP1 Pathway Commons Protein-Protein Interactions 1.0 null RAP1B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03618 XPOT Pathway Commons Protein-Protein Interactions 1.0 null Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18866 PFDN2 Pathway Commons Protein-Protein Interactions 1.0 null EEF1A1 Hub Proteins Protein-Protein Interactions 1.0 null DCTN2 Pathway Commons Protein-Protein Interactions 1.0 null ADK Pathway Commons Protein-Protein Interactions 1.0 null ICOS LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00518029 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05991 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68491 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02466 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.055869 BRD-K81795824_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 0.850398 Perturb_2486_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 FU97 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.10902 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.35937 TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNM3 Pathway Commons Protein-Protein Interactions 1.0 null GNAL Pathway Commons Protein-Protein Interactions 1.0 null BAG6 Pathway Commons Protein-Protein Interactions 1.0 null PNP Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55C-0326-SM-3GAF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960137 Perturb_11418_OE_HOXD13_SRP297429 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.79819 PRMT5 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WCDI-0008-SM-47JYE GTEx Tissue Sample Gene Expression Profiles 1.0 1.27518 BL922 (CUL9) NURSA Protein Complexes 1.0 null Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEACAM3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00601721 BL3893 (RAD9A) NURSA Protein Complexes 1.0 null DCK LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00549008 GTEX-RU72-0726-SM-46MUW GTEx Tissue Sample Gene Expression Profiles 1.0 0.934644 Perturb_7285_KO_ACTC1_SRP060637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.67505 CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.898221 HIC1_01_205 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59925 SLC29A1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00468372 ventral endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05734 ARL2 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EOL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 3.05964 CTPS1 Pathway Commons Protein-Protein Interactions 1.0 null TFAP2A JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-UPK5-2026-SM-4JBIM GTEx Tissue Sample Gene Expression Profiles 1.0 1.10776 JUNB Pathway Commons Protein-Protein Interactions 1.0 null COCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RBM6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00409782 AP2A1 Pathway Commons Protein-Protein Interactions 1.0 null TET1 ChEA Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IKBKG Pathway Commons Protein-Protein Interactions 1.0 null NME5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00520358 rheumatoid arthritis GWASdb SNP-Phenotype Associations 1.0 1.72883 Perturb_7485_OE_Mir489_SRP155560 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 DMS-114 GDSC Cell Line Gene Expression Profiles 1.0 1.73971 BL1690 (MAD1L1) NURSA Protein Complexes 1.0 null Valine-tRNA ligase InterPro Predicted Protein Domain Annotations 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUW1-0226-SM-4BOOS GTEx Tissue Sample Gene Expression Profiles 1.0 0.879836 metampicillin-1440 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902228 G3BP1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM5-23873026-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.873718 EHEB GDSC Cell Line Gene Expression Profiles -1.0 -2.40857 SARS2 Pathway Commons Protein-Protein Interactions 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.424199 CHD1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNX3 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null connective tissue disease GWASdb SNP-Disease Associations 1.0 0.269038 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.891884 MYH4 Pathway Commons Protein-Protein Interactions 1.0 null NU-1025-313 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XBEC-1326-SM-4AT69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83851 physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.080428 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61342 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828061 DHX9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X261-0011-R7A-SM-4E3JJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15654 18280641-table2 GeneSigDB Published Gene Signatures 1.0 null gigantocellular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.937798 Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.09262 GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70284 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Atrophy CTD Gene-Disease Associations 1.0 1.21919 leaf disc TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.795208 NCIH1793_LUNG CCLE Cell Line Proteomics 1.0 4.02009 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14911 GTEX-S32W-1526-SM-4AD6Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.836435 BL437 (NCOA2) NURSA Protein Complexes 1.0 null PPT1 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.9234 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.212586 SYK Pathway Commons Protein-Protein Interactions 1.0 null RCC2 Pathway Commons Protein-Protein Interactions 1.0 null fruit TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.104515 PSMD11 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OOBJ-0008-SM-3NB26 GTEx Tissue Sample Gene Expression Profiles 1.0 0.838369 structure GeneRIF Biological Term Annotations 1.0 null VCL Pathway Commons Protein-Protein Interactions 1.0 null 12531789-TableS1a GeneSigDB Published Gene Signatures 1.0 null DJM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05344 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10731 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.27933 samples GeneRIF Biological Term Annotations 1.0 null ERG ChEA Transcription Factor Targets 1.0 null PSMB2 Pathway Commons Protein-Protein Interactions 1.0 null SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32328 Hepatomegaly CTD Gene-Disease Associations 1.0 1.47374 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966579 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.999875 Phosphoric acid HMDB Metabolites of Enzymes 1.0 null HUCCT1 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.917575 Perturb_17045_KD_BATF3_SRP230607 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.8682 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.57564 sjogren's syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.614747 atovaquone-4786 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hsa-miR-760 MiRTarBase microRNA Targets 1.0 null outer CP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.94147 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.862122 abnormal joint morphology GWASdb SNP-Phenotype Associations 1.0 0.352167 SGK1 Hub Proteins Protein-Protein Interactions 1.0 null BL2289 (BTBD12) NURSA Protein Complexes 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null CORL24 CCLE Cell Line Gene Expression Profiles -1.0 -1.90791 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040453 VDAC1 Pathway Commons Protein-Protein Interactions 1.0 null marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214388 KYSE520 CCLE Cell Line Gene Expression Profiles -1.0 -1.49074 dienestrol-6208 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMARCA5 Pathway Commons Protein-Protein Interactions 1.0 null HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04024 Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-N87 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52661 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40935 M14 BioGPS Cell Line Gene Expression Profiles -1.0 -0.918962 PLCB3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00364149 PSMD2 Pathway Commons Protein-Protein Interactions 1.0 null Cystic Fibrosis_Pancreas_GSE769 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.26061 TCFCP2L1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Superior olivary complex, periolivary region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3507 ILF2 Pathway Commons Protein-Protein Interactions 1.0 null regulation of metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_1088_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.36166 HP1BP3 Pathway Commons Protein-Protein Interactions 1.0 null DBH LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00608413 GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916212 aortic valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.323365 GTEX-QDVN-2226-SM-2S1PM GTEx Tissue Sample Gene Expression Profiles 1.0 1.1051 CAND1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null DHX30 Pathway Commons Protein-Protein Interactions 1.0 null HT55 CCLE Cell Line Gene CNV Profiles -1.0 -1.35467 COV504 CCLE Cell Line Gene CNV Profiles -1.0 -1.33091 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.973305 RPL18A Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCNN1G LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00485953 ab92734 (PJA2) NURSA Protein Complexes 1.0 null TAL1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.848111 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles 1.0 1.07367 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP2M1 Pathway Commons Protein-Protein Interactions 1.0 null RPL7 Pathway Commons Protein-Protein Interactions 1.0 null salivary gland HPA Tissue Gene Expression Profiles -1.0 -1.32283 PCBP1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XMD1-0011-R3B-SM-4AT5R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18771 PRKAG1 MSigDB Cancer Gene Co-expression Modules 1.0 null trna metabolic process GO Biological Process Annotations 2015 1.0 null hsa-miR-4668-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KPNA2 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A204_SOFT_TISSUE CCLE Cell Line Proteomics 1.0 2.34862 CAMKV LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00457261 mebhydrolin-4795 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-UPK5-0226-SM-3GAEV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02005 regulation of macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68688 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33621 CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4695_KD_Srsf3_SRP059321 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.94053 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13881 NEK9 Pathway Commons Protein-Protein Interactions 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.32464 RPL3 Pathway Commons Protein-Protein Interactions 1.0 null heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null testicular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.418394 flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085747 hexamethonium bromide-1482 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BL4386 (MAGED2) NURSA Protein Complexes 1.0 null Perturb_16745_KO_Ncor2_ERP131241 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-Q2AG-1126-SM-48U1P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.945897 MYH2 Pathway Commons Protein-Protein Interactions 1.0 null BL2458 (UBE2L3) NURSA Protein Complexes 1.0 null KMM1 CCLE Cell Line Gene CNV Profiles 1.0 1.5592 LPXN LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00728824 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05791 POLR1C LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0044861 ATP1A2 Pathway Commons Protein-Protein Interactions 1.0 null BL57 (HELLS) NURSA Protein Complexes 1.0 null vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055632 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.987264 Adenosine triphosphate HMDB Metabolites of Enzymes 1.0 null GTEX-X261-0011-R6B-SM-4E3J8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26509 CHEK1 Pathway Commons Protein-Protein Interactions 1.0 null amygdalo-striatal transition Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46784 ICAM2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00467037 TUBB6 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1013 BL587 (FEN1) NURSA Protein Complexes 1.0 null MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.13148 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nifedipine-1856 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8176-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arsenic CTD Gene-Chemical Interactions 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.58689 Pyrophosphate HMDB Metabolites of Enzymes 1.0 null RPL10 Pathway Commons Protein-Protein Interactions 1.0 null RPL21 Pathway Commons Protein-Protein Interactions 1.0 null MYOG ENCODE Transcription Factor Targets 1.0 null PU.1-20513432-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41116 DECR1 Pathway Commons Protein-Protein Interactions 1.0 null Prostatic Neoplasms CTD Gene-Disease Associations 1.0 1.15256 DCXR Pathway Commons Protein-Protein Interactions 1.0 null husk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.750818 binding GO Molecular Function Annotations 2015 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042834 GTEX-POYW-0526-SM-2XCEY GTEx Tissue Sample Gene Expression Profiles 1.0 1.04543 CTCF-21964334-BJAB-B-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COLO201 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3ac_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71249 GTEX-PSDG-0008-SM-48TE5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37446 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null superior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39542 ACP1 Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YTHDF2 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.90427 pons TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.271952 APEH Pathway Commons Protein-Protein Interactions 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.47565 INPPL1 Pathway Commons Protein-Protein Interactions 1.0 null S100A7 Pathway Commons Protein-Protein Interactions 1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.966097 GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.97992 PICALM Pathway Commons Protein-Protein Interactions 1.0 null MKN7_STOMACH CCLE Cell Line Proteomics 1.0 3.36307 biotin-3289 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding InterPro Predicted Protein Domain Annotations 1.0 null VCAM1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles 1.0 1.00133 ATAD3A Pathway Commons Protein-Protein Interactions 1.0 null diethylstilbestrol_mus musculus_gpl6887_gse37969 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null JJN3 CCLE Cell Line Gene CNV Profiles 1.0 1.87272 ZR751 CCLE Cell Line Gene Expression Profiles -1.0 -1.8903 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11056_KD_Eif4ebp3_SRP251186 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13448 BL4015 (PPP1R13B) NURSA Protein Complexes 1.0 null UCK2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00624403 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84984 estradiol_homo sapiens_gpl571_gds4052 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null connective tissue cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044872 GTEX-X4XY-0011-R8A-SM-46MVC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.79758 IGF1_OE_GDS3484_542_human_MCF-7 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.72587 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03184 HSPA8 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -2.04719 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.985778 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FARSB Pathway Commons Protein-Protein Interactions 1.0 null adenocarcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TFAM Pathway Commons Protein-Protein Interactions 1.0 null hypocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084106 Perturb_7976_KO_Npm1/Smc3_SRP337222 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.19948 AP3M1 Pathway Commons Protein-Protein Interactions 1.0 null GOLGA7 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XMD1-0011-R2B-SM-4AT5N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43803 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00811 Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8139-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 5707885-6385 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79929 ATP2A2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3239_KO_Tsc2_SRP227934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.5893 CUL7 Pathway Commons Protein-Protein Interactions 1.0 null r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81341 Perturb_15365_KO_Klf2_SRP064312 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.85435 CBC41 (NAT10) NURSA Protein Complexes 1.0 null MOLP2 CCLE Cell Line Gene Expression Profiles 1.0 2.02872 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29687 ADCY2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00570852 L1236 CCLE Cell Line Gene CNV Profiles 1.0 1.4724 GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857583 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57663 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03891 r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29258 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null BL482 (MAP3K7IP3) NURSA Protein Complexes 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5932-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null H3K79me2_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43571 GNA12 Pathway Commons Protein-Protein Interactions 1.0 null CBC751 (USP9X) NURSA Protein Complexes 1.0 null Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.81589 RPS6KA1 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.838738 FDFT1 Pathway Commons Protein-Protein Interactions 1.0 null ARHGEF7 Pathway Commons Protein-Protein Interactions 1.0 null RPSA Pathway Commons Protein-Protein Interactions 1.0 null HT29 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.11712 GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.42517 BRD-K08547377_irinotecan hcl )trihydrate)_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TE-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058268 CEBPB_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090885 BL1585 (EGFR) NURSA Protein Complexes 1.0 null PPP4R3A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00668774 SFPI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null KLC1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_14656_KD_LINC00673_SRP102315 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40591 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61116 RPL5 Pathway Commons Protein-Protein Interactions 1.0 null cyclopenthiazide-4813 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null style TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.240826 RhoGDIbeta_KD_GDS2864_634_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040095 BL6604 (CDC42EP3) NURSA Protein Complexes 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.892923 prdm1_21670299_e18dot5_small_intestine_lof_mouse_gpl6887_gse29658 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.387681 GTEX-QMR6-0011-R2A-SM-32PKV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843137 RPS11 Pathway Commons Protein-Protein Interactions 1.0 null UWB1_289 COSMIC Cell Line Gene Mutation Profiles 1.0 null BL1239 (MAML1) NURSA Protein Complexes 1.0 null Low Set Ears DisGeNET Gene-Disease Associations 1.0 null TCP1 Pathway Commons Protein-Protein Interactions 1.0 null KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.54598 pimethixene-7468 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RPS4X Pathway Commons Protein-Protein Interactions 1.0 null Presubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3022 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null ANKFY1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08974 SNU-61 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.17256 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null OVMANA CCLE Cell Line Gene Expression Profiles -1.0 -1.50026 Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null articaine-7272 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SET Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13581_OE_Trpc1_SRP291421 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 IPO9 Pathway Commons Protein-Protein Interactions 1.0 null culture medium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.639214 PABPC3 Pathway Commons Protein-Protein Interactions 1.0 null TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null pirlindole-5497 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL1242 (MAML2) NURSA Protein Complexes 1.0 null BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K42805893_HG-14-8-02_HA1E_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 intracellular immature spore COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.356324 Perturb_15819_KO_PINK1_SRP343083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.88184 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -2.21428 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.54598 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles 1.0 0.955342 GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00044 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09926 CORO1C Pathway Commons Protein-Protein Interactions 1.0 null DoTc2-4510 GDSC Cell Line Gene Expression Profiles -1.0 -1.97106 DUSP9 Pathway Commons Protein-Protein Interactions 1.0 null Hep3B2-1-7 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.11174 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.037 SW1990 CCLE Cell Line Gene CNV Profiles 1.0 2.44326 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06866 GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.24035 FLNC Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.11595 IFI30 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00492752 POLD1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54H-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAP2B Pathway Commons Protein-Protein Interactions 1.0 null Perturb_627_KD_USO1_SRP278225 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.28854 BRD-U61997977_WZ-4-145_HME1_24_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BL7446 (ZNF777) NURSA Protein Complexes 1.0 null Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15539 DNM2 Pathway Commons Protein-Protein Interactions 1.0 null Hemorrhage CTD Gene-Disease Associations 1.0 1.19672 BRD-K61717269_-666_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SERPINB8 Pathway Commons Protein-Protein Interactions 1.0 null gemcitabine_homo sapiens_gpl96_gse6914 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TRPM7_defectivemutant_306_GSE23102 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.45959 AP3B1 Pathway Commons Protein-Protein Interactions 1.0 null EIF4G3 Pathway Commons Protein-Protein Interactions 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null EME1 Pathway Commons Protein-Protein Interactions 1.0 null GFI1B ChEA Transcription Factor Targets 1.0 null GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869525 brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.157765 GATA1_G1E-ER4_mm9_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null ETS1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU1076 CCLE Cell Line Gene Expression Profiles -1.0 -2.05284 ACTR3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K69097969_VU0418939-2_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SEH1L Pathway Commons Protein-Protein Interactions 1.0 null SRY JASPAR Predicted Transcription Factor Targets 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07913 Weight Gain CTD Gene-Disease Associations 1.0 1.05423 HEATR1 Pathway Commons Protein-Protein Interactions 1.0 null NHLH2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00613689 Perturb_13351_KD_Trank1_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.97854 Epilepsy DisGeNET Gene-Disease Associations 1.0 null GTEX-T6MO-0003-SM-3NMAG GTEx Tissue Sample Gene Expression Profiles 1.0 0.888251 sirolimus_homo sapiens_gpl96_gds2494 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CCT5 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of primary metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856964 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29418 pallidal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4085 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054261 ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49412 Hyperplasia CTD Gene-Disease Associations 1.0 1.8909 PPIA Pathway Commons Protein-Protein Interactions 1.0 null lateral part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12056 regulation of translational elongation GO Biological Process Annotations 2015 1.0 null tetroquinone-3338 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29263 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19423 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 BLVRB Pathway Commons Protein-Protein Interactions 1.0 null TRMT2A Pathway Commons Protein-Protein Interactions 1.0 null FOXO3 JASPAR Predicted Transcription Factor Targets 1.0 null PMC3581534__F7 PFOCR Pathway Figure Associations 2023 1.0 null SC-126 (TP53) NURSA Protein Complexes 1.0 null BL2794 (TRIM24) NURSA Protein Complexes 1.0 null EEF1G Hub Proteins Protein-Protein Interactions 1.0 null MYO18A Pathway Commons Protein-Protein Interactions 1.0 null lung HPA Tissue Protein Expression Profiles -1.0 -0.737921 GART Pathway Commons Protein-Protein Interactions 1.0 null TUBB4B Pathway Commons Protein-Protein Interactions 1.0 null ARHGAP12 Pathway Commons Protein-Protein Interactions 1.0 null ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null Lateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05542 eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044775 PLK1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CUL4A Pathway Commons Protein-Protein Interactions 1.0 null BL3600 (TP53BP2) NURSA Protein Complexes 1.0 null BL3030 (ERBB2) NURSA Protein Complexes 1.0 null layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15384 FAM129A Pathway Commons Protein-Protein Interactions 1.0 null CCL1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00447185 MACF1 Pathway Commons Protein-Protein Interactions 1.0 null E2F1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_13345_KD_Sp1_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.44776 HNRNPL Pathway Commons Protein-Protein Interactions 1.0 null tuber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.733089 GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879334 posteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39694 arthritis GWASdb SNP-Disease Associations 1.0 0.487126 colonrectum_f HPA Tissue Sample Gene Expression Profiles -1.0 -1.09018 EEF1A2 Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.973305 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.873718 GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42341 lytic vacuole LOCATE Predicted Protein Localization Annotations 1.0 null NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869501 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Trachea BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.14332 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974596 GTX105364 (BRE) NURSA Protein Complexes 1.0 null purine nucleoside binding GO Molecular Function Annotations 2015 1.0 null tRNA aminoacylation for protein translation GO Biological Process Annotations 2023 1.0 null cotyledon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.413151 inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65222 IPO8 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U3ZH-0326-SM-3DB7A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.962421 IGF2BP1 Pathway Commons Protein-Protein Interactions 1.0 null UTP18 Pathway Commons Protein-Protein Interactions 1.0 null SC-71539 (MAGEA1) NURSA Protein Complexes 1.0 null GTEX-QEG5-1426-SM-447AS GTEx Tissue Sample Gene Expression Profiles 1.0 0.859128 DDB1 MSigDB Cancer Gene Co-expression Modules 1.0 null LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null U87 BioGPS Cell Line Gene Expression Profiles -1.0 -1.00332 estradiol-414 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null mantle zone of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32964 A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.992147 GTEX-T2YK-0005-SM-32QOV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.929249 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.982921 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_2917_KD_FOXO3_SRP325840 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.4743 mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0329 muscle TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null RPL13A Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSME3 Pathway Commons Protein-Protein Interactions 1.0 null NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.63645 HCC-1143 ProteomicsDB Cell Type and Tissue Protein Expression Profiles 1.0 1.10908 Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14766_KD_HDAC5_SRP265842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.5655 mantle zone of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4052 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.38043 mitochondrial membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.06341 UBA5 Pathway Commons Protein-Protein Interactions 1.0 null eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044066 Perturb_210_KO_Mki67_SRP295170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.0039 Perturb_1016_KO_Nt5e_SRP404924 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.92369 small molecule binding GO Molecular Function Annotations 2015 1.0 null r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66736 IDH3A Pathway Commons Protein-Protein Interactions 1.0 null Superior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32499 ESR2 JASPAR Predicted Transcription Factor Targets 1.0 null nucleic acid metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K07667918_linsitinib_HT29_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FAM49B Pathway Commons Protein-Protein Interactions 1.0 null AGPAT5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13449_KD_Hnrnpk_SRP146257 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.36367 RPL6 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10731 GTEX-NL3H-0011-R5a-SM-2I3GB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03173 forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.250627 FEV JASPAR Predicted Transcription Factor Targets 1.0 null FLI1 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF3B Pathway Commons Protein-Protein Interactions 1.0 null lymphoid cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Perturb_4212_KO_Mir140_SRP245562 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.95712 RNPEP Pathway Commons Protein-Protein Interactions 1.0 null HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null Cardiovascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null CAD Pathway Commons Protein-Protein Interactions 1.0 null ATP2A1 Pathway Commons Protein-Protein Interactions 1.0 null organelle envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.160456 GTEX-RTLS-0526-SM-2TF64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28763 Perturb_14601_KO_ASAP2_SRP258574 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 ATXN10 Pathway Commons Protein-Protein Interactions 1.0 null TTC9C Pathway Commons Protein-Protein Interactions 1.0 null OCRL LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00658371 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35621 ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15925 C170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.954144 EIF4G1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00531572 leucoplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.818993 mantle zone of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43209 Central amygdalar nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38535 TRDMT1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00546804 outer CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.889424 superficial stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19644 GTEX-OHPL-0126-SM-2HMJ7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.969606 mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46174 BRE Pathway Commons Protein-Protein Interactions 1.0 null LOX-1_OE_GDS4262_432_human_HAECT - aortic endothelial cell line - 2 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K79090631_CGP-60474_PC3_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21256 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.62469 NCIH1299 CCLE Cell Line Gene Expression Profiles 1.0 1.39518 regulation of biosynthetic process GO Biological Process Annotations 2015 1.0 null heart TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06499 Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.859216 S100A6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00427148 Perturb_5004_KO_Rinf_SRP200002 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.19104 proplastid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.621379 SZ in subgenual cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.930193 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46983 NR1H3-23393188-ATHEROSCLEROTIC-FOAM-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-X5EB-2226-SM-46MW4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.842699 LCP1 Pathway Commons Protein-Protein Interactions 1.0 null SCCPDH Pathway Commons Protein-Protein Interactions 1.0 null testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.43807 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.636315 Endopiriform nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06327 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null daunorubicin-4983 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-WFON-1926-SM-3LK7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.912731 ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.43167 VHL Pathway Commons Protein-Protein Interactions 1.0 null FBXO6 Pathway Commons Protein-Protein Interactions 1.0 null SW-620 cell ProteomicsDB Cell Type and Tissue Protein Expression Profiles -1.0 -1.44876 LC1SQSF CCLE Cell Line Gene Expression Profiles -1.0 -1.51198 MAP1B Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.38592 bezafibrate-4999 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894622 PES1 Pathway Commons Protein-Protein Interactions 1.0 null UBL5 Pathway Commons Protein-Protein Interactions 1.0 null hepatoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CAPNS1 Pathway Commons Protein-Protein Interactions 1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.401765 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47004 r8 part of lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50643 hacat HPA Cell Line Gene Expression Profiles -1.0 -1.24701 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1869 CREM ChEA Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Transcription Factor Targets 1.0 null ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0626 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.29725 NMD3 Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.951657 Perturb_550_KD_EWSR1FLI1_SRP273158 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.65581 LYPLA1 Pathway Commons Protein-Protein Interactions 1.0 null testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.20245 CEP41 Hub Proteins Protein-Protein Interactions 1.0 null EIF3I MSigDB Cancer Gene Co-expression Modules 1.0 null MAPK11 Pathway Commons Protein-Protein Interactions 1.0 null ATP2B1 Pathway Commons Protein-Protein Interactions 1.0 null BL894 (PAFAH1B1) NURSA Protein Complexes 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10129 Cadmium CTD Gene-Chemical Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38554 single-organism process GO Biological Process Annotations 2015 1.0 null Penis_Foreskin_Keratinocyte_Primary_Cells_skin02 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.30914 Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062496 limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33413 VAMP5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00555524 NB120-3333 (PSME3) NURSA Protein Complexes 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21613 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.27977 biofilm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.328262 BRD-K53780220_N-((1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_HT29_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10326 smooth muscle HPA Tissue Gene Expression Profiles 1.0 0.882818 OTUD5 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7132_OE_RNASEH1_SRP257541 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTF1 MotifMap Predicted Transcription Factor Targets 1.0 null SMARCB1 Pathway Commons Protein-Protein Interactions 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.954144 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041246 HSP90AB1 Pathway Commons Protein-Protein Interactions 1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 SEPT7 Pathway Commons Protein-Protein Interactions 1.0 null STAU1 Pathway Commons Protein-Protein Interactions 1.0 null ERG-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null meptazinol-4774 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TRIM33_knockdown_304_GSE32903 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 4.25208 GM2313 BioGPS Cell Line Gene Expression Profiles -1.0 -1.78206 CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.451813 Diazinon CTD Gene-Chemical Interactions 1.0 null GTEX-V1D1-0526-SM-4JBGW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.85945 Perturb_15133_OE_Klf10_SRP360603 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -16.6647 JDP2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12192_KD_HPRT1_SRP259972 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.74242 mefexamide-7478 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 0.8286 GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62817 quinpirole-3539 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07956 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5555-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRAP1 Pathway Commons Protein-Protein Interactions 1.0 null Posterolateral visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41764 CNOT1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.962471 adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094936 superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0593 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null EIF4G2 Pathway Commons Protein-Protein Interactions 1.0 null RXRA-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4454 MAP1LC3B2 Pathway Commons Protein-Protein Interactions 1.0 null STMN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XYKS-2526-SM-4BOPX GTEx Tissue Sample Gene Expression Profiles 1.0 1.1581 hsa-miR-324-3p MiRTarBase microRNA Targets 1.0 null Progressive Microcephaly DisGeNET Gene-Phenotype Associations 1.0 null GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles 1.0 1.22643 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216528 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.858869 DYNC1I2 Pathway Commons Protein-Protein Interactions 1.0 null LNCaP cell ProteomicsDB Cell Type and Tissue Protein Expression Profiles 1.0 0.907416 17909032-Table3 GeneSigDB Published Gene Signatures 1.0 null PSMA4 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.10744 SRSF1 Pathway Commons Protein-Protein Interactions 1.0 null SH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null GTEX-TSE9-0011-R4A-SM-3DB7H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.840971 POU5F1-16518401-CHIP-PET-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MEF2A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00456468 GTEX-QVJO-0126-SM-3GIK4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.921123 SPP1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00429596 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.01023 GTEX-NPJ7-0011-R4a-SM-2I3GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00262 Perturb_13233_OE_Rnaseh1_SRP056871 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.3658 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AHCY Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01319 INSM1 JASPAR Predicted Transcription Factor Targets 1.0 null mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00935 Perturb_7319_KO_MIAT_SRP060637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.03553 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31126 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles 1.0 0.938658 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.37678 rheumatoid arthritis GWASdb SNP-Disease Associations 1.0 1.81169 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88678 BL2791 (PTEN) NURSA Protein Complexes 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.844756 19061838-TableS7 GeneSigDB Published Gene Signatures 1.0 null Perturb_5252_KO_Klf2/Snd1_SRP311785 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.4443 NCKAP1L Pathway Commons Protein-Protein Interactions 1.0 null ATP5A1 Pathway Commons Protein-Protein Interactions 1.0 null bone inflammation disease GWASdb SNP-Disease Associations 1.0 0.465834 ALYREF Pathway Commons Protein-Protein Interactions 1.0 null LCLC103H CCLE Cell Line Gene Expression Profiles 1.0 1.38954 AP2S1 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.25658 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16382 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTA2 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFE3 Pathway Commons Protein-Protein Interactions 1.0 null FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null HUPT3 CCLE Cell Line Gene CNV Profiles 1.0 2.4616 SCAP Pathway Commons Protein-Protein Interactions 1.0 null Ectorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79786 STAT5B Pathway Commons Protein-Protein Interactions 1.0 null lobelanidine-1747 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null lateral parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09811 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00825 CBC701 (PALLD) NURSA Protein Complexes 1.0 null HSPA1B Pathway Commons Protein-Protein Interactions 1.0 null a-PTEN (WG) (PTEN) NURSA Protein Complexes 1.0 null HCT116 Achilles Cell Line Gene Essentiality Profiles 1.0 1.05778 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liver TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null pelvic varices DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.712796 ACLY Pathway Commons Protein-Protein Interactions 1.0 null mitochondrial part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.197993 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69099 Neural Tube Defects CTD Gene-Disease Associations 1.0 1.20946 E2A MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_4864_KD_SON_ERP003259 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SE5C-0426-SM-4BRUI GTEx Tissue Sample Gene Expression Profiles 1.0 1.03045 Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.829708 ATP5C1 Pathway Commons Protein-Protein Interactions 1.0 null organic acid metabolic process GO Biological Process Annotations 2015 1.0 null sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.0433 SU-DHL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29263 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.993598 KIDINS220 Pathway Commons Protein-Protein Interactions 1.0 null FTSJ1 Pathway Commons Protein-Protein Interactions 1.0 null G-401 COSMIC Cell Line Gene Mutation Profiles 1.0 null IARS Pathway Commons Protein-Protein Interactions 1.0 null Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.875027 r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94756 Perturb_15816_KO_PINK1_SRP343083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.56993 BL2185 (TSC2) NURSA Protein Complexes 1.0 null KRT12 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00601457 CDK2 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1 ChEA Transcription Factor Targets 1.0 null NCL Pathway Commons Protein-Protein Interactions 1.0 null sirolimus_homo sapiens_gpl6244_gse15703 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.47323 PSMC3 Pathway Commons Protein-Protein Interactions 1.0 null HADHA Pathway Commons Protein-Protein Interactions 1.0 null cytisine-6217 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DPYSL2 Pathway Commons Protein-Protein Interactions 1.0 null EXOC5 Pathway Commons Protein-Protein Interactions 1.0 null superior parietal lobule, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.871404 17660535-TableS4c GeneSigDB Published Gene Signatures 1.0 null BL2795 (TRIM24) NURSA Protein Complexes 1.0 null adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.19251 DDX42 Pathway Commons Protein-Protein Interactions 1.0 null PFKL Pathway Commons Protein-Protein Interactions 1.0 null ACTN4 Pathway Commons Protein-Protein Interactions 1.0 null RPS5 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null yohimbine-1119 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL992 (INCENP) NURSA Protein Complexes 1.0 null XPO1 Pathway Commons Protein-Protein Interactions 1.0 null cytosol GO Cellular Component Annotations 2015 1.0 null GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 0.98029 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.962163 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.962137 CL11 CCLE Cell Line Gene CNV Profiles -1.0 -1.98028 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null M6PR Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null culture condition:antigen-presenting cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-RVPU-0011-R7A-SM-2XCAB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23125 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44877 SCAMP3 Pathway Commons Protein-Protein Interactions 1.0 null YWHAQ Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05121 integument TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 supramarginal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.943858 MAP1A Pathway Commons Protein-Protein Interactions 1.0 null soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.26179 BRD-K40329609_NCGC00184830-01_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_1677_KO_Jak3_SRP287984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896281 MEMO1 Pathway Commons Protein-Protein Interactions 1.0 null C170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.87206 EEF1B2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFG8-0726-SM-3GILP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859636 BL7700 (ARHGAP29) NURSA Protein Complexes 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null leukocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.94126 peripheral vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.203275 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lytic vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.099754 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13881 GABP-19822575-HEPG2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.01862 RPN1 Pathway Commons Protein-Protein Interactions 1.0 null Superior olivary complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08539 GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36658 HTK CCLE Cell Line Gene Expression Profiles 1.0 1.59367 PAFAH1B3 Pathway Commons Protein-Protein Interactions 1.0 null PDCD10 Pathway Commons Protein-Protein Interactions 1.0 null CCAR1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS15A Pathway Commons Protein-Protein Interactions 1.0 null PPID LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00549307 RNH1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K61717269_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.840975 nordihydroguaiaretic acid-524 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051248 CBC552 (TACC3) NURSA Protein Complexes 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null carmustine-6888 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GAPDH Pathway Commons Protein-Protein Interactions 1.0 null ARPC3 Pathway Commons Protein-Protein Interactions 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939219 FLI1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.994069 SUCLG2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00635472 NKX2-5-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Prestwick-689-7173 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null XPO7 Pathway Commons Protein-Protein Interactions 1.0 null PHLPP1 Pathway Commons Protein-Protein Interactions 1.0 null whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.783141 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29073 outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3041 CLGN Pathway Commons Protein-Protein Interactions 1.0 null CDK1 Pathway Commons Protein-Protein Interactions 1.0 null ARHGEF2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13713_KO_ASXL2_SRP360138 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.77889 GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46189 BRD-K18724229_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null EIF4A1 Pathway Commons Protein-Protein Interactions 1.0 null layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34864 caudal group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04019 Subiculum, ventral part, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24208 TIPRL Pathway Commons Protein-Protein Interactions 1.0 null BRD-K99532291_SPB02303_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HBG1 Pathway Commons Protein-Protein Interactions 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.56573 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16718 BL8288 (TOR1AIP1) NURSA Protein Complexes 1.0 null PSMD13 Pathway Commons Protein-Protein Interactions 1.0 null heart ProteomicsDB Cell Type and Tissue Protein Expression Profiles -1.0 -1.48323 GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1042 ETF1 Pathway Commons Protein-Protein Interactions 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.81404 spleen HPA Tissue Protein Expression Profiles -1.0 -0.737921 BZW2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00776 16651409-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907688 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.93792 NUP155 Pathway Commons Protein-Protein Interactions 1.0 null respiratory chain COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.133739 IRF2BP1 Pathway Commons Protein-Protein Interactions 1.0 null BL2581 (RPTOR) NURSA Protein Complexes 1.0 null Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.39702 plant embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.081759 GNAT3 Pathway Commons Protein-Protein Interactions 1.0 null CCT8 Pathway Commons Protein-Protein Interactions 1.0 null catalytic complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042114 proadifen-7165 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RPS13 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -4.16823 GTEX-XYKS-1426-SM-4BRUO GTEx Tissue Sample Gene Expression Profiles 1.0 0.836759 EIF4H Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPK5-0326-SM-3GAF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917327 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL19 Pathway Commons Protein-Protein Interactions 1.0 null CIRBP Pathway Commons Protein-Protein Interactions 1.0 null membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.397423 GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13673 valine-tRNA ligase activity GO Molecular Function Annotations 2023 1.0 null Nervous System Malformations CTD Gene-Disease Associations 1.0 1.03827 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.892531 GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 0.936271 USP15 Pathway Commons Protein-Protein Interactions 1.0 null USF1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL3033 (ERBB2) NURSA Protein Complexes 1.0 null Perturb_1785_KO_Atf4_SRP201328 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.40779 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21035 ZFX ChEA Transcription Factor Targets 1.0 null LRPPRC Pathway Commons Protein-Protein Interactions 1.0 null NDUFA2 Pathway Commons Protein-Protein Interactions 1.0 null AIMP2 Pathway Commons Protein-Protein Interactions 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47004 bone disease GWASdb SNP-Disease Associations 1.0 0.326462 cellular_component GO Cellular Component Annotations 2015 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21682 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LCLC-103H GDSC Cell Line Gene Expression Profiles 1.0 2.21731 Poisoning CTD Gene-Disease Associations 1.0 1.08584 20174566-TableS1 GeneSigDB Published Gene Signatures 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.36031 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05874 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01531 MKNK1 Pathway Commons Protein-Protein Interactions 1.0 null cellular amino acid metabolic process GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.38652 TXN Pathway Commons Protein-Protein Interactions 1.0 null gynoecium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.212936 hypersensitivity reaction type ii disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05809 APRT Pathway Commons Protein-Protein Interactions 1.0 null DOCK8 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_11885_KO_Stat3_SRP307561 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.54132 r5 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09825 POLR2AphosphoS2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RB-01A-12R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925184 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 1.5168 15474998-tableS1c GeneSigDB Published Gene Signatures 1.0 null BRD-K82837433_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NONO Pathway Commons Protein-Protein Interactions 1.0 null Perturb_2856_Mut_VHL_SRP404927 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.3143 Penis_Foreskin_Keratinocyte_Primary_Cells_skin03 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.90692 MCM6 Pathway Commons Protein-Protein Interactions 1.0 null BUB3 Pathway Commons Protein-Protein Interactions 1.0 null layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56993 disease GWASdb SNP-Disease Associations 1.0 0.037001 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.20347 RPL38 Pathway Commons Protein-Protein Interactions 1.0 null mitochondrion COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Perturb_7403_KD_HNRNPA2B1_SRP010280 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.32505 LRRC59 Pathway Commons Protein-Protein Interactions 1.0 null XPO4 Pathway Commons Protein-Protein Interactions 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.61933 RPL32 Pathway Commons Protein-Protein Interactions 1.0 null BL2753 (LCOR) NURSA Protein Complexes 1.0 null MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.6807 Perturb_4861_KD_SON_ERP003259 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.219 LMO2 ChEA Transcription Factor Targets 1.0 null NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.45692 DNAJC7 Pathway Commons Protein-Protein Interactions 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20958 Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80118 Nanotubes, Carbon CTD Gene-Chemical Interactions 1.0 null GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.887668 SDF2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3832_KO_Foxd2_SRP307575 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.91364 ACTN3 Pathway Commons Protein-Protein Interactions 1.0 null RPMI-8226 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.69549 CCT2 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC-202 ProteomicsDB Cell Type and Tissue Protein Expression Profiles 1.0 0.961912 BYSL Pathway Commons Protein-Protein Interactions 1.0 null sense organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 VTA1 Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.84432 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02262 CAKI-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.47664 cyanocobalamin-1315 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null valyl-trna aminoacylation GO Biological Process Annotations 2015 1.0 null soleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.218186 Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gustatory areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44457 TYMS Pathway Commons Protein-Protein Interactions 1.0 null outer CP in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09633 KLF12 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00555192 varicocele DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.726929 Aminoacyl-tRNA synthetase, class I, conserved site InterPro Predicted Protein Domain Annotations 1.0 null Cytosolic tRNA aminoacylation Reactome Pathways 2014 1.0 null SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.54543 LHX2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00754743 MUS81 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36559 Perturb_5474_KO_Tsc2_SRP227934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.35632 GTEX-QEG4-0426-SM-33HC3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865873 striatal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32806 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923135 hsa-miR-331-3p MiRTarBase microRNA Targets 1.0 null sirolimus_mus musculus_gpl1261_gse5332 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ITSN2 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03356 NB6 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.22527 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DDX6 Pathway Commons Protein-Protein Interactions 1.0 null RSC1A1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00606312 BRD-K79090631_CGP-60474_HEPG2_24_h_0.04_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.63569 NUDT21 Pathway Commons Protein-Protein Interactions 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Paragigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19973 hsa-miR-92a-3p MiRTarBase microRNA Targets 1.0 null IRF8-22096565-GC-B-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF JASPAR Predicted Transcription Factor Targets 1.0 null Perturb_17220_KD_NANOG_ERP128142 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 negatively GeneRIF Biological Term Annotations 1.0 null Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain InterPro Predicted Protein Domain Annotations 1.0 null PLEC Pathway Commons Protein-Protein Interactions 1.0 null PMVK Pathway Commons Protein-Protein Interactions 1.0 null DDX3X Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYOD1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nod2_21335489_hek293_lof_human_gpl570_gds4416 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.640092 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7586_KO_CAMTA1_SRP360744 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.2786 A427 COSMIC Cell Line Gene Mutation Profiles 1.0 null BL7633 (COBRA1) NURSA Protein Complexes 1.0 null Perturb_16839_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.33458 DHCR24 Pathway Commons Protein-Protein Interactions 1.0 null Fetal Death CTD Gene-Disease Associations 1.0 1.50398 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.36984 GTEX-XYKS-2126-SM-4E3IB GTEx Tissue Sample Gene Expression Profiles 1.0 1.03803 SLC25A24 Pathway Commons Protein-Protein Interactions 1.0 null vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.076737 ATF7 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_17307_KD_Chrm5_SRP222274 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.98014 regulation of macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null NQO1 Pathway Commons Protein-Protein Interactions 1.0 null GM12878 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.14363 CNBP Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03409 17295094-GeneList GeneSigDB Published Gene Signatures 1.0 null CNOT10 Pathway Commons Protein-Protein Interactions 1.0 null GM133 BioGPS Cell Line Gene Expression Profiles -1.0 -0.830575 Prestwick-984-6603 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PPIH Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OHPN-0011-R3A-SM-2I5FC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0153 GNB1L Pathway Commons Protein-Protein Interactions 1.0 null PYCR1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30181 FYCO1 Pathway Commons Protein-Protein Interactions 1.0 null PRMT1 Pathway Commons Protein-Protein Interactions 1.0 null FASN Pathway Commons Protein-Protein Interactions 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.437972 DAOY COSMIC Cell Line Gene Mutation Profiles 1.0 null EIF4G1 Pathway Commons Protein-Protein Interactions 1.0 null Nutritional deficiency, NEC_Skeletal Myocyte_GSE1776 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 0.763508 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11258 PRC2_EDD_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38335 GANAB Pathway Commons Protein-Protein Interactions 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.848111 heart_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.01132 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.67228 Macular degeneration_Fibroblast_GSE1719 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.44879 Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.664232 STIP1 Pathway Commons Protein-Protein Interactions 1.0 null inner CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10077 EIF3D Pathway Commons Protein-Protein Interactions 1.0 null Perturb_11579_KO_QPC_SRP166848 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.16128 GTEX-S7PM-0126-SM-4AD6S GTEx Tissue Sample Gene Expression Profiles 1.0 0.904241 Lung adenocarcinoma_LUAD_TCGA-J2-8194-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_5752_KO_Apoe_SRP115310 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.96791 JAM3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00554681 Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATP5O Pathway Commons Protein-Protein Interactions 1.0 null HS255T CCLE Cell Line Gene Expression Profiles -1.0 -2.17493 USF1 JASPAR Predicted Transcription Factor Targets 1.0 null P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-W5X1-0826-SM-3GILN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902467 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null hsa-miR-484 MiRTarBase microRNA Targets 1.0 null Rheumatoid Arthritis DisGeNET Gene-Disease Associations 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urinary bladder HPA Tissue Protein Expression Profiles 1.0 1.25289 BRD-K72414522_AZD-5438_LNCAP_3_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20078 EPB41 Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00852 MIF Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles 1.0 1.33379 Perturb_12544_KO_Ctnnb1_SRP194249 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.95124 Aminoacyl-tRNA synthetase, class Ia InterPro Predicted Protein Domain Annotations 1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null PRKAG1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6478-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 salivarygland_6b HPA Tissue Sample Gene Expression Profiles -1.0 -2.15001 EIF3C Pathway Commons Protein-Protein Interactions 1.0 null MKN45 CCLE Cell Line Gene CNV Profiles 1.0 1.55617 ALDH1L2 Pathway Commons Protein-Protein Interactions 1.0 null CANX Pathway Commons Protein-Protein Interactions 1.0 null gut TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 UBA1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0072041 NUP93 Pathway Commons Protein-Protein Interactions 1.0 null Sarcoidosis DisGeNET Gene-Disease Associations 1.0 null NCIH2286 CCLE Cell Line Gene CNV Profiles -1.0 -1.33413 aminoacyl trna biosynthesis KEGG Pathways 1.0 null Perturb_14790_KD_SF3A2_SRP191866 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Posterolateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69314 GTEX-Q2AI-0526-SM-2I3EJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.4215 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3133 TAL1_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null GTEX-PWO3-0011-R2A-SM-2S1OX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.929884 MSH2 Pathway Commons Protein-Protein Interactions 1.0 null PA2G4 Pathway Commons Protein-Protein Interactions 1.0 null karpas707 HPA Cell Line Gene Expression Profiles 1.0 1.95431 BOLA2 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ8-0011-R7a-SM-2HMJV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30216 L-Valine HMDB Metabolites of Enzymes 1.0 null WDR77 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29409 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.934038 UBE2D3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0050665 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.21882 SQRDL Pathway Commons Protein-Protein Interactions 1.0 null CD2AP Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4769-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Frontal pole, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11641 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.78799 purine ribonucleoside triphosphate binding GO Molecular Function Annotations 2015 1.0 null GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.18526 RCOR1 ENCODE Transcription Factor Targets 1.0 null MOLP2 CCLE Cell Line Gene CNV Profiles 1.0 1.89214 GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.23954 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045971 SAFB Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12244_KD_KDM5A_SRP325972 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 HLA-DMB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00443146 inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.39116 TCFCP2L1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null DDOST Pathway Commons Protein-Protein Interactions 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00756 COPB2 Pathway Commons Protein-Protein Interactions 1.0 null trichostatin A-413 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07737 LASV_FML29_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.872371 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10501 epididymis HPA Tissue Protein Expression Profiles 1.0 1.25289 BL1476 (PNKP) NURSA Protein Complexes 1.0 null BL5212 (DOCK10) NURSA Protein Complexes 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Myopia DisGeNET Gene-Disease Associations 1.0 null GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 2.21317 TTLL12 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GOTO COSMIC Cell Line Gene Mutation Profiles 1.0 null r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00872 SMC3 ENCODE Transcription Factor Targets 1.0 null ATP4A Pathway Commons Protein-Protein Interactions 1.0 null RBM4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.65691 RRM1 Pathway Commons Protein-Protein Interactions 1.0 null EPS15L1 Pathway Commons Protein-Protein Interactions 1.0 null CNOT11 Pathway Commons Protein-Protein Interactions 1.0 null CHD7 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_10307_KO_Myc_SRP114370 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.24928 CAL-39 GDSC Cell Line Gene Expression Profiles -1.0 -1.99954 SNRPD1 Pathway Commons Protein-Protein Interactions 1.0 null trypanosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.385565 GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37759 r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34509 CBC702 (PALLD) NURSA Protein Complexes 1.0 null respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4842 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCOA5 Pathway Commons Protein-Protein Interactions 1.0 null GFPT1 Pathway Commons Protein-Protein Interactions 1.0 null Atherosclerosis DisGeNET Gene-Disease Associations 1.0 null PAX6 JASPAR Predicted Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1919 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43148 H1FX Pathway Commons Protein-Protein Interactions 1.0 null BL5657 (ANKZF1) NURSA Protein Complexes 1.0 null GSK3A_KD_GDS4305_180_human_MOLM-14 myeloid leukemia cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SRM Pathway Commons Protein-Protein Interactions 1.0 null XPO5 Pathway Commons Protein-Protein Interactions 1.0 null LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null deferoxamine_homo sapiens_gpl91_gse1056 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_14159_KO_UTX_SRP399588 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056179 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.03849 PFN1 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GTEX-WRHU-1026-SM-4E3ID GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848267 GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.832766 BL73 (CLSPN) NURSA Protein Complexes 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A3EE-01A-11R-A206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAA15 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43781 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02236 GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0858 IGF2R Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3322_KO_Aim2_SRP201902 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.47973 YWHAE Pathway Commons Protein-Protein Interactions 1.0 null PHB2 Pathway Commons Protein-Protein Interactions 1.0 null CACYBP Pathway Commons Protein-Protein Interactions 1.0 null Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61246 20937356-TableS2 GeneSigDB Published Gene Signatures 1.0 null Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIAA0196 Pathway Commons Protein-Protein Interactions 1.0 null small molecule metabolic process GO Biological Process Annotations 2015 1.0 null specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.061149 POLR2AphosphoS5_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.233878 Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NTPCR Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Y-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 3 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29532 GTEX-UTHO-0011-R2A-SM-3GIKC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04074 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null heart muscle HPA Tissue Gene Expression Profiles -1.0 -1.11062 Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06063 NUP214 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58274 J82 CCLE Cell Line Gene CNV Profiles 1.0 1.78776 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29263 PPARgamma:RXRalpha MotifMap Predicted Transcription Factor Targets 1.0 null STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null RREB1 JASPAR Predicted Transcription Factor Targets 1.0 null KYO1 CCLE Cell Line Gene Expression Profiles 1.0 2.25001 IST-MEL1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NPJ8-2226-SM-3TW8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2649 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.76578 MAPKAPK2 Pathway Commons Protein-Protein Interactions 1.0 null EIF3A Pathway Commons Protein-Protein Interactions 1.0 null CAPN1 Pathway Commons Protein-Protein Interactions 1.0 null SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.31525 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null IL7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00515614 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902897 PDCD6IP Pathway Commons Protein-Protein Interactions 1.0 null HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.80424 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99235 MAPK14 Pathway Commons Protein-Protein Interactions 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12712 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.054846 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.5129 r4 part of medial paralemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02576 ATAD3C Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8007-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.981205 mantle zone of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11771 an3ca HPA Cell Line Gene Expression Profiles 1.0 1.13076 SKG-IIIa GDSC Cell Line Gene Expression Profiles -1.0 -1.45856 viral membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.253291 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles 1.0 1.01979 hsa-miR-4654 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null colon BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01276 TAL1_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-0126-SM-48TBW GTEx Tissue Sample Gene Expression Profiles 1.0 0.998559 Perturb_10621_OE_Mst1_SRP398098 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GTEX-XXEK-0126-SM-4BRVU GTEx Tissue Sample Gene Expression Profiles 1.0 1.15294 male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.388538 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null P4HA2 Pathway Commons Protein-Protein Interactions 1.0 null orbital frontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45386 SDHB Pathway Commons Protein-Protein Interactions 1.0 null tiratricol-1412 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-P4QS-0326-SM-2I3EU GTEx Tissue Sample Gene Expression Profiles 1.0 1.09324 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.89552 PRR4 Pathway Commons Protein-Protein Interactions 1.0 null blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213471 Pontine gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2596 BRD-K74710236_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15384 VAMP8 Pathway Commons Protein-Protein Interactions 1.0 null Central amygdalar nucleus, capsular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1724 SF3A1 Pathway Commons Protein-Protein Interactions 1.0 null OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43771 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21297 anion binding GO Molecular Function Annotations 2015 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.08929 GTEX-NL3H-0011-R2a-SM-2I3GG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05669 superficial stratum of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42166 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75857 GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles 1.0 1.48194 superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66736 COLO-668 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_5066_KD_Ccnc_SRP325525 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.41754 HNRNPM Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.06438 VASP Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.6852 CFL1 Pathway Commons Protein-Protein Interactions 1.0 null ABL1_druginhibition_77_GSE24493 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.80284 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.72963 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964797 DLX5_OE_GDS4577_345_mouse_Otic vesicle derived 2B1 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-QDT8-0011-R4A-SM-32PKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.942063 IMPDH2 Pathway Commons Protein-Protein Interactions 1.0 null VM-CUB-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.61642 Perturb_13232_OE_Rnaseh1_SRP056871 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.54381 JQ006 (MSH2) NURSA Protein Complexes 1.0 null USP12 Pathway Commons Protein-Protein Interactions 1.0 null epitiostanol-4788 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hypersensitivity reaction disease GWASdb SNP-Disease Associations 1.0 0.76818 EED Pathway Commons Protein-Protein Interactions 1.0 null viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 blood TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 BRD-U64521890_XMD16-144_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02262 RAB35 Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.963392 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.64587 MCM4 Pathway Commons Protein-Protein Interactions 1.0 null PSMD3 Pathway Commons Protein-Protein Interactions 1.0 null Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21797 TBC1D2B Pathway Commons Protein-Protein Interactions 1.0 null Urinary Bladder Neoplasms CTD Gene-Disease Associations 1.0 1.16666 CHD2 ENCODE Transcription Factor Targets 1.0 null deferoxamine-4317 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SK-MM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.363185 CRO-AP2 COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsal periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03792 ATP1A3 Pathway Commons Protein-Protein Interactions 1.0 null HMGB2 Pathway Commons Protein-Protein Interactions 1.0 null TBP-23326641-C3H10T1-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07883 nucleotide binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SOX4 MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-296-3p MiRTarBase microRNA Targets 1.0 null medial part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24401 a-BRCC36 (BRCC3) NURSA Protein Complexes 1.0 null HNRNPR Pathway Commons Protein-Protein Interactions 1.0 null CHI3L1 Pathway Commons Protein-Protein Interactions 1.0 null H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATP2A3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.65086 GTEX-RNOR-0826-SM-2TF5C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.838843 rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.25658 BRD-K08307026_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-OHPL-2026-SM-3TW8R GTEx Tissue Sample Gene Expression Profiles 1.0 1.48594 Fatty Liver CTD Gene-Disease Associations 1.0 1.4294 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 2.52433 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX21 Pathway Commons Protein-Protein Interactions 1.0 null NECTIN3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00725771 TPR Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5365-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2286 CCLE Cell Line Gene Expression Profiles -1.0 -1.48536 GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.04331 GTEX-SSA3-0226-SM-32QPN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.83742 Astigmatism DisGeNET Gene-Disease Associations 1.0 null Prenatal Injuries CTD Gene-Disease Associations 1.0 1.20196 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14018 STAT3 Pathway Commons Protein-Protein Interactions 1.0 null PSMA7 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 0.916682 RBMX Pathway Commons Protein-Protein Interactions 1.0 null FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null Perturb_6238_KO_Setd1a_SRP365947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.21723 LPCAT1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975961 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.552251 GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.894444 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.853748 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null capan2 HPA Cell Line Gene Expression Profiles -1.0 -0.841815 EGR1-23403033-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-RUSQ-0226-SM-47JWT GTEx Tissue Sample Gene Expression Profiles 1.0 0.921461 GTEX-R55G-1626-SM-48FF4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06831 BL2194 (USP4) NURSA Protein Complexes 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2486 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09932 CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PNR MotifMap Predicted Transcription Factor Targets 1.0 null imatinib_homo sapiens_gpl96_gds3046 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL697 (CC2D1A) NURSA Protein Complexes 1.0 null culture condition:cd4+ cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Cognition Disorders CTD Gene-Disease Associations 1.0 1.13724 SC-6243 (TP53) NURSA Protein Complexes 1.0 null RPL22 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K73610817_NCGC00183371-01_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.40208 microscopic GeneRIF Biological Term Annotations 1.0 null TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04695 Liver Cirrhosis CTD Gene-Disease Associations 1.0 1.24591 SNRPF Pathway Commons Protein-Protein Interactions 1.0 null chloroplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.790564 Perturb_5333_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.9199 lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49656 Lateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16384 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null RPS24 Pathway Commons Protein-Protein Interactions 1.0 null LN319 Achilles Cell Line Gene Essentiality Profiles 1.0 1.13616 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 2.01538 FKBP4 Pathway Commons Protein-Protein Interactions 1.0 null EIF3H Pathway Commons Protein-Protein Interactions 1.0 null AIMP1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52994 TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.04512 EEF2 Pathway Commons Protein-Protein Interactions 1.0 null EIF3I Pathway Commons Protein-Protein Interactions 1.0 null Glutathione S-transferase, N-terminal InterPro Predicted Protein Domain Annotations 1.0 null Perturb_10363_KD_Rorc_SRP185851 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.95071 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H524 GDSC Cell Line Gene Expression Profiles 1.0 1.50609 BL475 (AHCTF1) NURSA Protein Complexes 1.0 null Fibrosis CTD Gene-Disease Associations 1.0 1.62357 Perturb_3260_KD_PHB2_SRP089927 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.3495 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.9562 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05874 Gustatory areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1526 GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20221 RPS3A Pathway Commons Protein-Protein Interactions 1.0 null BL4961 (ABI1) NURSA Protein Complexes 1.0 null UBE3C Pathway Commons Protein-Protein Interactions 1.0 null ALB Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T2IS-0426-SM-32QPE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8011 16651409-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2961_KD_Nsd1/Nsd2/Setd2_SRP058766 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 RPMI 8226 BioGPS Cell Line Gene Expression Profiles 1.0 1.99767 K562 CCLE Cell Line Gene Expression Profiles 1.0 1.84808 GARS Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-OV-3 GDSC Cell Line Gene Expression Profiles -1.0 -1.87588 prostate gland ProteomicsDB Cell Type and Tissue Protein Expression Profiles -1.0 -0.898232 KHSRP Pathway Commons Protein-Protein Interactions 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.909584 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47412 TARDBP Pathway Commons Protein-Protein Interactions 1.0 null SLR25 CCLE Cell Line Gene Expression Profiles 1.0 1.69943 Perturb_480_KD_LncRNAPLANE_SRP294372 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.64081 GTEX-RU72-0226-SM-46MUD GTEx Tissue Sample Gene Expression Profiles 1.0 0.910659 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.61933 Perturb_15400_KD_AR_SRP014809 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.218 nucleoside binding GO Molecular Function Annotations 2015 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4785 mitochondrial envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.167125 BL2388 (CUL4A) NURSA Protein Complexes 1.0 null GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.745 NR4A2 JASPAR Predicted Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KM12 CCLE Cell Line Gene CNV Profiles -1.0 -1.89373 UBD Pathway Commons Protein-Protein Interactions 1.0 null HNRNPH3 Pathway Commons Protein-Protein Interactions 1.0 null EJM CCLE Cell Line Gene CNV Profiles 1.0 1.73159 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 H3K27ac_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPL-0326-SM-33HC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842067 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null a-HAUSP (USP7) NURSA Protein Complexes 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAS1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.57647 A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.833582 Perturb_17223_KD_NANOG_ERP128142 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 imatinib_homo sapiens_gpl96_gds3045 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Aspartate Aminotransferase Measurement DisGeNET Gene-Phenotype Associations 1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 1.25289 mitochondrial membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.172468 GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.926494 PSMB1 Pathway Commons Protein-Protein Interactions 1.0 null cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EIF3L Pathway Commons Protein-Protein Interactions 1.0 null cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.656033 posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.987821 17297478-SuppTable5 GeneSigDB Published Gene Signatures 1.0 null Precancerous Conditions CTD Gene-Disease Associations 1.0 1.19345 GTEX-XMD1-0011-R9A-SM-4AT49 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02789 posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.897005 methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Perturb_7408_KD_HNRNPM_SRP010280 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.10527 TAL1 ENCODE Transcription Factor Targets 1.0 null DES_KO_GDS4804_171_mouse_young skeletal muscles GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.390455 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21035 RPL18 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14062 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17616 BL1022 (FAM184B) NURSA Protein Complexes 1.0 null A101D GDSC Cell Line Gene Expression Profiles 1.0 2.20974 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.13155 STK33_NOMO MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null PRRC2C Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ADRBK1 Pathway Commons Protein-Protein Interactions 1.0 null MMP9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00503716 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.9889 Perturb_2544_KO_OVOL2_SRP347819 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 REL JASPAR Predicted Transcription Factor Targets 1.0 null RARS Pathway Commons Protein-Protein Interactions 1.0 null ATG7 Pathway Commons Protein-Protein Interactions 1.0 null Primary somatosensory area, barrel field, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13061 liver cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19346 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JVM-3 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.64168 HH CCLE Cell Line Gene CNV Profiles -1.0 -1.76008 r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66628 PMC4437738__F3 PFOCR Pathway Figure Associations 2023 1.0 null CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.07196 Perturb_2868_Mut_HIF1A_SRP404927 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Prostatic Diseases CTD Gene-Disease Associations 1.0 1.24812 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 2.15246 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Posterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64926 DRG1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00553 cell pole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.325327 KIF2C Pathway Commons Protein-Protein Interactions 1.0 null GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles 1.0 1.27387 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828061 DAZAP1 Pathway Commons Protein-Protein Interactions 1.0 null TIAL1 Pathway Commons Protein-Protein Interactions 1.0 null NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.38541 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.824047 BRD-U07805514_saracatinib_PC3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TNPO2 Pathway Commons Protein-Protein Interactions 1.0 null 15459177-Table1 GeneSigDB Published Gene Signatures 1.0 null CFHR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0053207 Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null RENBP LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00505339 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HIST1H1E Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51863 r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34786 UBC Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HIST1H2BL Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null hsa-miR-93-3p MiRTarBase microRNA Targets 1.0 null GTEX-OHPL-2426-SM-48TDN GTEx Tissue Sample Gene Expression Profiles 1.0 0.88319 GTEX-XV7Q-1526-SM-4BRWB GTEx Tissue Sample Gene Expression Profiles 1.0 1.22321 regulation of cellular process GO Biological Process Annotations 2015 1.0 null BL2840 (UIMC1) NURSA Protein Complexes 1.0 null EPRS Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07186 BL3509 (KDM4A) NURSA Protein Complexes 1.0 null RAC2 Pathway Commons Protein-Protein Interactions 1.0 null CTSD Pathway Commons Protein-Protein Interactions 1.0 null wortmannin-404 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MARS Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSP90AA1 Pathway Commons Protein-Protein Interactions 1.0 null BL1096 (DYRK2) NURSA Protein Complexes 1.0 null SUDHL1 CCLE Cell Line Gene Expression Profiles 1.0 1.84402 ACTC1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_3294_KD_RORC_SRP117629 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 sleeping sickness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.695103 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null probucol-4666 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6779 RPS27 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K53417444_OTSSP167_A549_24_h_0.12_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H2AFY Pathway Commons Protein-Protein Interactions 1.0 null CORO7 Pathway Commons Protein-Protein Interactions 1.0 null ATG3 Pathway Commons Protein-Protein Interactions 1.0 null UWB1.289 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.27279 NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NOP56 Pathway Commons Protein-Protein Interactions 1.0 null GCN1L1 Pathway Commons Protein-Protein Interactions 1.0 null DDX17 Pathway Commons Protein-Protein Interactions 1.0 null ticarcillin-7185 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TWIST1_01_254 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.58715 BICR22 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.54121 PPP2R3A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00625222 4-hydroxyphenazone-1997 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042461 COPE Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles 1.0 1.43162 cervix, uterine HPA Tissue Protein Expression Profiles -1.0 -1.26179 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81658 STON2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5329_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.93907 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03975 MYBL2-22936984-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MYC_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of translation GO Biological Process Annotations 2015 1.0 null CNOT3 Pathway Commons Protein-Protein Interactions 1.0 null FUBP1 Pathway Commons Protein-Protein Interactions 1.0 null KIF5C Pathway Commons Protein-Protein Interactions 1.0 null MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.850839 Cell Transformation, Neoplastic CTD Gene-Disease Associations 1.0 1.04647 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KURAMOCHI Achilles Cell Line Gene Essentiality Profiles -1.0 -1.12105 Perturb_4858_KD_SON_ERP003259 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-OOBK-0226-SM-2YUMF GTEx Tissue Sample Gene Expression Profiles 1.0 0.941714 GTEX-OXRO-0126-SM-2YUN4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.99001 pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.224001 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045156 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.20384 GTEX-U4B1-1026-SM-4DXT1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952971 lateral part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43303 GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51719 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.593649 Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZG-0726-SM-33HBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.899048 PDHA1 Pathway Commons Protein-Protein Interactions 1.0 null deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12051 GTEX-R53T-0926-SM-3GADH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.942457 FAR1 Pathway Commons Protein-Protein Interactions 1.0 null layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60954 TIA1_KO_GSE54418_263_mouse_spinal cord GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PIK3CG_knockdown_96_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.84093 SEC63 Pathway Commons Protein-Protein Interactions 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null meiotic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.53346 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00781 GTEX-PSDG-0626-SM-2S1OE GTEx Tissue Sample Gene Expression Profiles 1.0 1.1283 GTEX-QEG5-0326-SM-2S1PB GTEx Tissue Sample Gene Expression Profiles 1.0 1.10453 SPTBN1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Epileptic Encephalopathy DisGeNET Gene-Disease Associations 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.05737 KRT6A Pathway Commons Protein-Protein Interactions 1.0 null CCT3 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K37764012_PF-3758309_PC3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null amygdalohippocampal transition zone, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17123 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MS4A6A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00439774 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31543 TERF2 Pathway Commons Protein-Protein Interactions 1.0 null FN1 Pathway Commons Protein-Protein Interactions 1.0 null tRNA aminoacylation GO Biological Process Annotations 2023 1.0 null CAL51 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.994069 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.3329 KM12 CCLE Cell Line Gene Expression Profiles -1.0 -1.725 endocytic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.111858 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.885488 BRD-K14788918_-666_VCAP_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K74710236_VU0410183-2_PC3_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09764 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.79465 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6239_KO_Setd1a_SRP365947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.08682 retina TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 HIP1 Pathway Commons Protein-Protein Interactions 1.0 null Memory Disorders CTD Gene-Disease Associations 1.0 1.25745 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null U343 Achilles Cell Line Gene Essentiality Profiles 1.0 1.23841 RFC1 MSigDB Cancer Gene Co-expression Modules 1.0 null Perturb_13673_KO_Mir155_SRP057986 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.3142 GTEX-OHPM-0326-SM-33HCA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12841 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15937 SC-14031 (FOXH1) NURSA Protein Complexes 1.0 null primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.9153 Nephritis CTD Gene-Disease Associations 1.0 1.39563 NKM-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.04539 OGDHL Pathway Commons Protein-Protein Interactions 1.0 null Arthritis, Psoriatic HuGE Navigator Gene-Phenotype Associations 1.0 null salivarygland_6c HPA Tissue Sample Gene Expression Profiles -1.0 -1.19284 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.839381 SIN3A ENCODE Transcription Factor Targets 1.0 null GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07495 PRDX1 Pathway Commons Protein-Protein Interactions 1.0 null hypersensitivity reaction disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051458 regulation of cellular macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null U2AF2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_17215_KO_Izumo1r_SRP354764 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.4641 GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.981707 FLNA Pathway Commons Protein-Protein Interactions 1.0 null RCC-JW COSMIC Cell Line Gene Mutation Profiles 1.0 null PTPN23 Pathway Commons Protein-Protein Interactions 1.0 null ATP2B4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8535_KD_Rbfox1/Rbfox3_SRP062242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.94056 DHX15 Pathway Commons Protein-Protein Interactions 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null BL3602 (TP53BP2) NURSA Protein Complexes 1.0 null Perturb_10445_KD_LTR362_SRP062702 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CBX3 Pathway Commons Protein-Protein Interactions 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.899358 EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FOXM1_01_122 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59337 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.06605 SC-28749 (NCOA4) NURSA Protein Complexes 1.0 null Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.18884 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pRb_Deficiency_GDS3176_605_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD9 Pathway Commons Protein-Protein Interactions 1.0 null KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.945702 dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03578 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.42954 MCM2 Pathway Commons Protein-Protein Interactions 1.0 null RPA1 Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.74485 trna aminoacylation for protein translation GO Biological Process Annotations 2015 1.0 null MAX_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15030_Mut_Csf33_SRP347624 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20519 tonsil HPA Tissue Gene Expression Profiles 1.0 1.45014 ZWILCH Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.069639 SLC25A13 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8735_KD_SREBF1_SRP169608 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.94749 single-organism metabolic process GO Biological Process Annotations 2015 1.0 null SW1417_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 3.44251 HCT-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null colistin-4796 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.63071 RPS21 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50092 Perturb_2049_KO_Trp53_DRP003641 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.52531 fat_8a HPA Tissue Sample Gene Expression Profiles 1.0 1.09835 Perturb_9556_KO_IKKa_SRP111864 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-OIZF-1526-SM-3MJGY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86866 SEC24C Pathway Commons Protein-Protein Interactions 1.0 null C4A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00537923 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868869 KM12 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.02836 POLR2A_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JJN-3 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.777 hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.21467 LMAN2 Pathway Commons Protein-Protein Interactions 1.0 null hindlimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077596 LGALS1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13359_KD_Foxf2_SRP137807 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.20874 GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20524 SMCHD1 Pathway Commons Protein-Protein Interactions 1.0 null CYFIP1 Pathway Commons Protein-Protein Interactions 1.0 null SERPINH1 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null betahistine-6611 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SFXN3 Pathway Commons Protein-Protein Interactions 1.0 null MAP1LC3B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925865 diethylstilbestrol_mus musculus_gpl81_gds982 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null E2F4_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01953 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMM1 CCLE Cell Line Gene Expression Profiles 1.0 1.61763 GTEX-XYKS-1626-SM-4BRUQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.914376 PMC3486512__F3 PFOCR Pathway Figure Associations 2023 1.0 null FSCN1 Pathway Commons Protein-Protein Interactions 1.0 null vitamin c_homo sapiens_gpl570_gds3635 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.8497 H3K36me3_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00125 DJM-1 GDSC Cell Line Gene Expression Profiles -1.0 -2.15887 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null GTEX-QVJO-0011-R2A-SM-2S1QK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869522 Perturb_15399_KD_RUVBL1_SRP361862 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.70827 vegetative cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.457987 merozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.456828 EGR1 ChEA Transcription Factor Targets 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.70327 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 2.0854 CW-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null threedimensional GeneRIF Biological Term Annotations 1.0 null Perturb_192_KD_Serpine2_SRP056340 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.4462 CDK8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00470571 GATA2 ChEA Transcription Factor Targets 1.0 null WFS1_KO_GDS4526_111_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HUNS1 CCLE Cell Line Gene Expression Profiles 1.0 1.36081 BL6096 (MOV10) NURSA Protein Complexes 1.0 null forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF4E MSigDB Cancer Gene Co-expression Modules 1.0 null GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27182 RPS19 Pathway Commons Protein-Protein Interactions 1.0 null ZNF300 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00415306 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1665 ALAD Pathway Commons Protein-Protein Interactions 1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05546 CYFIP2 Pathway Commons Protein-Protein Interactions 1.0 null ceftazidime-1721 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 FOXP1 ChEA Transcription Factor Targets 1.0 null NCIH660 Achilles Cell Line Gene Essentiality Profiles 1.0 2.66306 REH COSMIC Cell Line Gene Mutation Profiles 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.64835 GTEX-OHPN-0011-R4A-SM-2I5FD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3922 Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.75486 outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16378 HSP90B1 Pathway Commons Protein-Protein Interactions 1.0 null S100A8 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QS-0526-SM-2I3ET GTEx Tissue Sample Gene Expression Profiles 1.0 0.878844 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_4384_KD_PC4_SRP340634 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.12148 doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_16502_KD_ASCL1_SRP325888 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.68087 GTEX-XLM4-0011-R9A-SM-4AT45 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22302 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70196 outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928073 envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.110577 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HBA2 Pathway Commons Protein-Protein Interactions 1.0 null BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.825187 RPL13 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-RUSQ-1826-SM-2TF6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.05713 trna aminoacylation GO Biological Process Annotations 2015 1.0 null cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.634358 NR1I2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00584108 DLST Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Temporal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92674 developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.058005 Neurofibromatosis DisGeNET Gene-Disease Associations 1.0 null Microcephaly DisGeNET Gene-Phenotype Associations 1.0 null STK33 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3739 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null electron GeneRIF Biological Term Annotations 1.0 null PKBalpha_KO_GDS1784_194_mouse_Embryonic fibroblasts (MEFs) - 2h GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null posttranscriptional regulation of gene expression GO Biological Process Annotations 2015 1.0 null PSMD7 Pathway Commons Protein-Protein Interactions 1.0 null Abnormality Of Brain Morphology DisGeNET Gene-Phenotype Associations 1.0 null GTEX-U8XE-0526-SM-3DB8R GTEx Tissue Sample Gene Expression Profiles 1.0 1.23424 MRTO4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12726_KO_MITF_SRP255094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.6606 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.325701 GTEX-WZTO-0011-R1B-SM-3NMAR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.85701 DDX5 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-4670-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null C-33-A Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.7064 NSD3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00510193 GTEX-O5YT-0926-SM-48TDG GTEx Tissue Sample Gene Expression Profiles 1.0 0.851382 mantle zone of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12056 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.898404 mantle zone of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24216 GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13034 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.6764 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044202 ATM_knockdown_18_GDS1852 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.71222 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76284 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null MREG LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00429077 Perturb_193_KD_Serpine2_SRP056340 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.6373 GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles 1.0 0.914323 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.07043 HS172T CCLE Cell Line Gene Expression Profiles -1.0 -1.50161 HSP90AB4P Pathway Commons Protein-Protein Interactions 1.0 null KP-N-RT-BM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AG-0526-SM-2S1PW GTEx Tissue Sample Gene Expression Profiles 1.0 0.855691 GTEX-S4Q7-0003-SM-3NM8M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936124 TFDP1_02_71 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60596 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945311 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881641 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.02104 HCFC1 ENCODE Transcription Factor Targets 1.0 null culture condition TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.859677 RAVER1 Pathway Commons Protein-Protein Interactions 1.0 null Primary somatosensory area, mouth, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12857 medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46308 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.36899 Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29263 ACTG1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PVOW-0426-SM-2XCF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06169 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66464 APOC2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00578823 lisinopril-5504 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17985 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW1990 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 CHCHD3 Pathway Commons Protein-Protein Interactions 1.0 null gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.220953 skeletal muscle HPA Tissue Protein Expression Profiles -1.0 -1.26179 translation GO Biological Process Annotations 2023 1.0 null Perturb_1123_KO_Myc_SRP168941 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.33585 UBE2NL Pathway Commons Protein-Protein Interactions 1.0 null OVKATE CCLE Cell Line Gene Expression Profiles -1.0 -3.48543 aminoacyl-trna synthetase multienzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.498636 ginkgolide A-1324 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26833 EIF3E Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NL3H-0011-R1a-SM-48TDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49521 spaglumic acid-7465 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null COPA Pathway Commons Protein-Protein Interactions 1.0 null FLOT1 Pathway Commons Protein-Protein Interactions 1.0 null fulvestrant_homo sapiens_gpl570_gse22533 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.20658 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.05953 PDIA6 Pathway Commons Protein-Protein Interactions 1.0 null GNA13 Pathway Commons Protein-Protein Interactions 1.0 null FKBP8 Pathway Commons Protein-Protein Interactions 1.0 null mitochondrial respiratory chain COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.259837 other source TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Adenosine monophosphate HMDB Metabolites of Enzymes 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ligase activity, forming aminoacyl-trna and related compounds GO Molecular Function Annotations 2015 1.0 null ROBO3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00510515 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM49A Pathway Commons Protein-Protein Interactions 1.0 null BL4310 (SAPS2) NURSA Protein Complexes 1.0 null posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04716 PLAG1 JASPAR Predicted Transcription Factor Targets 1.0 null KRT9 Pathway Commons Protein-Protein Interactions 1.0 null RHAG LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00514099 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMD1-0008-SM-4AT41 GTEx Tissue Sample Gene Expression Profiles 1.0 0.945996 CARS Pathway Commons Protein-Protein Interactions 1.0 null UBE2M Pathway Commons Protein-Protein Interactions 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.573439 GTEX-PWO3-0011-R1A-SM-2I5EW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12568 RPL12 Pathway Commons Protein-Protein Interactions 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 CHD4 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4792 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 MAP1LC3B Hub Proteins Protein-Protein Interactions 1.0 null hydrocortisone_homo sapiens_gpl201_gse21909 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null nucleoside phosphate binding GO Molecular Function Annotations 2015 1.0 null POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null amino acid activation GO Biological Process Annotations 2015 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834349 HDMYZ_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 3.51481 Perturb_7679_KD_NBAS_SRP267245 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 quinisocaine-4791 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-RWSA-0626-SM-2XCBD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07917 GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900095 LANCL2 Pathway Commons Protein-Protein Interactions 1.0 null GSN LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00595837 RPS23 Pathway Commons Protein-Protein Interactions 1.0 null LAIR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00883388 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.31283 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.863519 BRD-K79090631_CGP-60474_PC3_24_h_0.04_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-U8XE-1426-SM-3DB8Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.834004 HLF JASPAR Predicted Transcription Factor Targets 1.0 null ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RP1_KO_GDS1845_190_mouse_Retinas GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null XRCC4 Pathway Commons Protein-Protein Interactions 1.0 null ODF3L1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00854077 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20519 SFPQ Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NPJ7-0011-R5a-SM-33HBK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44623 GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32554 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32912 MAX_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLIN3 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HIST3H3 Pathway Commons Protein-Protein Interactions 1.0 null KM-H2 COSMIC Cell Line Gene Mutation Profiles 1.0 null fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.264696 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.15378 dimenhydrinate-6352 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BL7338 (LRWD1) NURSA Protein Complexes 1.0 null Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.16866 ACTG2 Pathway Commons Protein-Protein Interactions 1.0 null NCIH460_LUNG CCLE Cell Line Proteomics 1.0 2.36072 POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1 MotifMap Predicted Transcription Factor Targets 1.0 null HBG2 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Weight Loss CTD Gene-Disease Associations 1.0 1.44735 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.94856 ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.863988 C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29896 molindone-4784 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PKLR Pathway Commons Protein-Protein Interactions 1.0 null BL1104 (CENPB) NURSA Protein Complexes 1.0 null SRSF9 Pathway Commons Protein-Protein Interactions 1.0 null PIAS1_KD_GSE44024_133_human_breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CCT4 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72636 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.20882 GTEX-SNOS-0426-SM-32PMH GTEx Tissue Sample Gene Expression Profiles 1.0 1.0133 GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21249 PHB Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2337 meclofenamic acid-1445 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.87454 GATA1 ENCODE Transcription Factor Targets 1.0 null BRD-A06352508_SB 218078_A375_6.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAP1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5327_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.30011 superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20161 STXBP2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles 1.0 1.52529 YES1 Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PM-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Diseases CTD Gene-Disease Associations 1.0 1.59311 GTEX-V1D1-0008-SM-4JBIJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.08346 TOMM34 Pathway Commons Protein-Protein Interactions 1.0 null OccipitalLobe BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.07637 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2578 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0752 Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.633144 ATP6V1H Pathway Commons Protein-Protein Interactions 1.0 null ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLTC Pathway Commons Protein-Protein Interactions 1.0 null SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.825238 Perturb_14730_KD_MAZ_SRP338457 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-T2YK-0008-SM-4DM6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.88448 Perturb_12322_KD_BMAL1_SRP186908 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.7666 COLO205 BioGPS Cell Line Gene Expression Profiles -1.0 -0.874847 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OAW28 CCLE Cell Line Gene Expression Profiles -1.0 -2.76721 LAN-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null cisplatin_mus musculus_gpl339_gds3099 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PIN1 Pathway Commons Protein-Protein Interactions 1.0 null LOXIMVI CCLE Cell Line Gene Expression Profiles 1.0 1.89469 Hypertrophy CTD Gene-Disease Associations 1.0 1.21695 ALDOA Pathway Commons Protein-Protein Interactions 1.0 null stained GeneRIF Biological Term Annotations 1.0 null MAX JASPAR Predicted Transcription Factor Targets 1.0 null rna metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17043 ITGA4 Pathway Commons Protein-Protein Interactions 1.0 null tardbp_19910924_hek293e_lof_human_gpl570_gds3730 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.150175 brain cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.37629 SCFD2 Pathway Commons Protein-Protein Interactions 1.0 null IFNGR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00555444 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902282 RPL4 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11287 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.824887 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24818 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18406 heart muscle HPA Tissue Protein Expression Profiles -1.0 -1.26179 TCF3 ENCODE Transcription Factor Targets 1.0 null ovary HPA Tissue Protein Expression Profiles -1.0 -1.26179 E2F1-26619117-HEPATOCYTES-MOUSE-LIVER ChEA Transcription Factor Targets 2022 1.0 null PYCR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00727303 CHMP4B Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BL1034 (ADNP) NURSA Protein Complexes 1.0 null Intercalated amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15959 internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SF1 Pathway Commons Protein-Protein Interactions 1.0 null harman-2806 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null A253 GDSC Cell Line Gene Expression Profiles -1.0 -1.84587 rostral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35809 SA1-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.173003 CTCF-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 4.66989 HCC1187_BREAST CCLE Cell Line Proteomics 1.0 7.57583 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16675 inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05746 TMOD3_KO_GDS4827_313_mouse_Liver erythroblast GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RUVBL2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-U61997977_WZ-4-145_HME1_24_h_1.11_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BL6415 (BCR) NURSA Protein Complexes 1.0 null DHCR7 Pathway Commons Protein-Protein Interactions 1.0 null SART3 Pathway Commons Protein-Protein Interactions 1.0 null organism form TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 17676974-TableS2 GeneSigDB Published Gene Signatures 1.0 null Central amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06129 HCST LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00523461 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.895876 CVB3_30min-Infection_None_GSE697 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.45585 16597596-TableS1-5 GeneSigDB Published Gene Signatures 1.0 null OVKATE Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.96947 JUND ENCODE Transcription Factor Targets 1.0 null RPS6KA2 Pathway Commons Protein-Protein Interactions 1.0 null frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Lateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24805 primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02132 CUL3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -3.32513 oxedrine-7150 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6032 Lung adenocarcinoma_LUAD_TCGA-80-5607-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42208 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.976578 MACROD1 Pathway Commons Protein-Protein Interactions 1.0 null propranolol_mus musculus_gpl6885_gse42534 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MPV17 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0074735 FAF2 Pathway Commons Protein-Protein Interactions 1.0 null mantle zone of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64611 TUBB Pathway Commons Protein-Protein Interactions 1.0 null YD8 CCLE Cell Line Gene Expression Profiles -1.0 -1.59286 boldine-2804 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null medial geniculate complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.86479 HBE1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_13330_KD_Nfat5_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.31185 DDX39B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.99251 ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.863628 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050573 EM-2 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.1601 retrotrapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72218 BL5941 (WNK1) NURSA Protein Complexes 1.0 null A431 GDSC Cell Line Gene Expression Profiles -1.0 -1.50961 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.10427 GTEX-P4QT-0008-SM-48TDZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.828796 Necrosis CTD Gene-Disease Associations 1.0 2.05307 single-organism cellular process GO Biological Process Annotations 2015 1.0 null PCMT1 Pathway Commons Protein-Protein Interactions 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.62497 gene expression GO Biological Process Annotations 2015 1.0 null HIP1R Pathway Commons Protein-Protein Interactions 1.0 null OVCAR4_OVARY CCLE Cell Line Proteomics 1.0 4.80735 EIF2S1 Pathway Commons Protein-Protein Interactions 1.0 null lupus erythematosus, systemic GAD Gene-Disease Associations 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC-2218 ProteomicsDB Cell Type and Tissue Protein Expression Profiles 1.0 1.29597 MAFK ENCODE Transcription Factor Targets 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.23362 Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESYT1 Pathway Commons Protein-Protein Interactions 1.0 null Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2449 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.619255 ANKHD1 Pathway Commons Protein-Protein Interactions 1.0 null CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39498 BHLHE40_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cleft palate DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.309204 LEPRE1 Pathway Commons Protein-Protein Interactions 1.0 null estradiol_homo sapiens_gpl570_gse5102 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-PX3G-0926-SM-48U12 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10375 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VHL Hub Proteins Protein-Protein Interactions 1.0 null skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058991 Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84489 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ERGIC3 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43771 MATR3 Pathway Commons Protein-Protein Interactions 1.0 null PLS3 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895871 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08348 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042941 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84605 BL8332 (C1orf55) NURSA Protein Complexes 1.0 null ATAD1 Pathway Commons Protein-Protein Interactions 1.0 null MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Edema HuGE Navigator Gene-Phenotype Associations 1.0 null TUR COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-0926-SM-48TDO GTEx Tissue Sample Gene Expression Profiles 1.0 0.865591 NCIH2170 CCLE Cell Line Gene Expression Profiles 1.0 1.37528 GTEX-Q2AG-0626-SM-2S1PV GTEx Tissue Sample Gene Expression Profiles 1.0 1.40425 GABARAPL2 Pathway Commons Protein-Protein Interactions 1.0 null Neoplasms CTD Gene-Disease Associations 1.0 1.64595 Leprosy HuGE Navigator Gene-Phenotype Associations 1.0 null Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00999 ANXA1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07044 NSUN2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K16189898_CHIR-99021_A549_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PRDX6 Pathway Commons Protein-Protein Interactions 1.0 null TRPV4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00662924 antimycin A-1414 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TSNAX Pathway Commons Protein-Protein Interactions 1.0 null Perturb_15050_KO_A2AR_SRP251523 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.388 GNAI2 Pathway Commons Protein-Protein Interactions 1.0 null phagolysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.144274 CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -1.4734 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052205 NAA38 Pathway Commons Protein-Protein Interactions 1.0 null TMA7 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00491659 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.6509 gastrocnemius TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.24804 periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46174 Learning Disorders CTD Gene-Disease Associations 1.0 1.46727 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PLS1 Pathway Commons Protein-Protein Interactions 1.0 null male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45301 DSC1 Pathway Commons Protein-Protein Interactions 1.0 null KRT2 Pathway Commons Protein-Protein Interactions 1.0 null FGFR3_druginhibition_36_GDS5023 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.21361 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PLAA Pathway Commons Protein-Protein Interactions 1.0 null PGK1 Pathway Commons Protein-Protein Interactions 1.0 null CBL Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00166 IST-SL2 COSMIC Cell Line Gene Mutation Profiles 1.0 null aminoacyl-tRNA ligase activity GO Molecular Function Annotations 2023 1.0 null LMNB1 Pathway Commons Protein-Protein Interactions 1.0 null staurosporine-312 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ERLIN1 Pathway Commons Protein-Protein Interactions 1.0 null feather TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.525166 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.55524 GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08584 HARS Pathway Commons Protein-Protein Interactions 1.0 null Perturb_2481_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32836 rpmi8226 HPA Cell Line Gene Expression Profiles 1.0 1.48121 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 RPS9 Pathway Commons Protein-Protein Interactions 1.0 null testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 2.36259 PMC4711185__F2 PFOCR Pathway Figure Associations 2023 1.0 null K-562 COSMIC Cell Line Gene Mutation Profiles 1.0 null SLC2A4 Hub Proteins Protein-Protein Interactions 1.0 null COR-L26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24617 hydrolase activity, acting on ester bonds GO Molecular Function Annotations 2015 1.0 null PSMD6 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13339_KD_Rybp_SRP149831 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.4965 liver HPA Tissue Protein Expression Profiles -1.0 -1.26179 CNIH3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00584675 outer CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.962965 etioplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.497015 Perturb_954_KO_Mfn1/Mfn2_SRP150413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.58649 pituitary GTEx Tissue Gene Expression Profiles 1.0 2.10661 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37846 NCI-H1703 GDSC Cell Line Gene Expression Profiles 1.0 1.48295 GNAS Pathway Commons Protein-Protein Interactions 1.0 null oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37873 UBA7 Pathway Commons Protein-Protein Interactions 1.0 null KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.830947 GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27186 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927638 MZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.833357 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.97915 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC1A5 Pathway Commons Protein-Protein Interactions 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.72992 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.982921 NCIH1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.33736 Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRP9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles 1.0 1.18532 inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32286 SRP14 Pathway Commons Protein-Protein Interactions 1.0 null inner CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.831938 BL1861 (NRIP1) NURSA Protein Complexes 1.0 null ATP5I Pathway Commons Protein-Protein Interactions 1.0 null RBM14 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1549_KO_Rpl23a_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.55119 SEC31A Pathway Commons Protein-Protein Interactions 1.0 null TAL1_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL6548 (RAI1) NURSA Protein Complexes 1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73108 Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.11798 GTEX-SNMC-0126-SM-2XCFO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03853 RPS7 Pathway Commons Protein-Protein Interactions 1.0 null outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09499 USMG5 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12377_KD_SOX9_SRP314898 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.29197 TUBAL3 Pathway Commons Protein-Protein Interactions 1.0 null varicose veins DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.483985 CEBPB ENCODE Transcription Factor Targets 1.0 null CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MCM7 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36474 HBB Pathway Commons Protein-Protein Interactions 1.0 null organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null GP1BB Pathway Commons Protein-Protein Interactions 1.0 null RPL17 Pathway Commons Protein-Protein Interactions 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.644858 NCIH1666_LUNG CCLE Cell Line Proteomics 1.0 4.29881 suxibuzone-7163 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SLC2A1 Pathway Commons Protein-Protein Interactions 1.0 null ATP6V1A Pathway Commons Protein-Protein Interactions 1.0 null Perturb_1686_OE_Mnx1_SRP373412 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 TUFM Pathway Commons Protein-Protein Interactions 1.0 null DNMT1 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8457_KO_FGFR4_SRP386785 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.48697 GTEX-XMD1-0011-R10A-SM-4AT4A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.896361 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NDUFS1 Pathway Commons Protein-Protein Interactions 1.0 null SW-480 cell ProteomicsDB Cell Type and Tissue Protein Expression Profiles -1.0 -1.3355 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.971679 AP1B1 Pathway Commons Protein-Protein Interactions 1.0 null PMC3008507__F5 PFOCR Pathway Figure Associations 2023 1.0 null