association	dataset	threshold value	standardized value
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7805
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mean spheric corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.33638
Red blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.513948
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12241
10703_ZNRD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.540799
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3491
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2157
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35687
A549_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152344
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Down_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157691
MCF7_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144642
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27939
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15001
A549_UNC1999_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0109758
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1777
7690_SCD_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512709
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175105
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142543
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133003
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2029
10875_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520176
K562_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149701
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155165
A549_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172284
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25341
K562_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169993
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11237
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22311
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31884
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.9575
PMC3470785-NIHMS377161-supplement-12.pdf-522-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200964
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15173
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76854
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.2372
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
162 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15494
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24312
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6347
K562_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177999
GSE146949_1_v_0_hemgn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81193_3_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215086_8_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
8887_THOC1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.588411
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120336_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198971_0_v_2_ncor2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Hesperadin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120273
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144479
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205963_0_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80107
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1021
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7045
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9879
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.599592
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9301
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228241
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1565
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2334
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE104022_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
10803_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.542473
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1051
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25866
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_7_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20191
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0895
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207787
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81193_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3969
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7785_SEPTIN2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.615316
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5392969-13045_2017_462_MOESM1_ESM.xlsx-Additional_file_3B-FOXO4_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4396
K562_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153918
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79896
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24469
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07793
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36544
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6605
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Luminespib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159684
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7169_RBM28_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.653147
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1323
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5154
1716_CNOT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.620055
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69029
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.820023
K562_Anacardic Acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164423
GSE217101_0_v_1_mcph1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21764
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4068
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9878113-fcvm-09-1056427.nxml--A_TGA_patients_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7995
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.7937
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05944
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3677
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9234
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
11152_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.731345
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90207
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12653
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11
1910_CSRNP3_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.771385
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47067
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04333
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25636
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158847
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21702
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5099
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47018
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01854
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12719
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41535
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5037
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr17_73191491_C_T_b38	GTEx eQTL 2025	1.0	3.33968
GSE135350_2_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.024
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26128
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56155
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17113
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5846
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5391
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.563795
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16941
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.19205
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Platelet alpha granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.13608
Fascia dentata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Flavopiridol HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134603
GSE143462_0_v_1_omipalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8639
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206784_2_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0912
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.36792
K562_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164863
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.634
K562_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136563
K562_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141098
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_2_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.02031
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9431
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7771
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uniplex complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
A549_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142418
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.963
7893_SEM1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.572832
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SHFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34328
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37087
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1658
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04005
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76638
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0289
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162053
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
8656_TAF1A_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.2327
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5481
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Disulfiram_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137783
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03377
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24824
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19583
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91843
K562_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189146
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6863
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9769
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21304
A549_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164565
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.640154
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5858
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32342
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7629
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-176-HOXC10_HOXC10	Rummagene Transcription Factor Associations 2026	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.558469
MCF7_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131206
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19202
PHOX2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10053
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_E20_814_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10611
8331_SPC24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524413
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.2443
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3306
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_PHA-680632_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104133
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016265
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7218
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alveolar lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.333
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.10057
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2104
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2116
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06828
PMC6543837-Table_9.XLSX-In_vivo_M2_LPS--Supplementary_Table_9_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03663
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7304
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42421
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RFX2_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0259557
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27727
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58646
GMNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07665
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19381
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152281
3447_GNL3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.60567
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1676
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.8722
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
4371_KIAA1958_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.814688
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.697
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1371
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46583
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11175
K562_A-366_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200623
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4079
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
9175_TOP2A_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.07748
PMM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75965
4951_MED28_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.68877
CREM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02848
GSE93309_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42789
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6779
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10879698-mmc1.pdf-12-ZNF2_ZNF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50605
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9222
K562_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171033
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207914_5_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spine synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2146
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2765
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9254
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49036
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12055
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6089
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1322
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.924
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4365
K562_BMS-911543_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147162
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8385
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_BRD4770_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160163
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78013
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00458
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72163
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0809
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7477
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9369
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0307
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52118
K562_Thiotepa_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173172
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6138
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7802
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6026875-MOL2-12-1104-s002.xlsx-List_of_Cancer_Associated_Molec-Tet-MIST1_Cancer_Molecules_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07359
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49433
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33135
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30021
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE97870,GSE97871_1_v_2_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAUS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30281
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6579
4954_MED31_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.09511
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89969
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06696
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5041
UFD1-NPL4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.72
PMC7585942-mmc4.xlsx-RBM10_KD-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3919
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04129
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126852
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150864
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47481
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4647
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03909
PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.04081
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9728
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.321
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1047
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32241
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24954
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33749
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09337
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.011
K562_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159785
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00374
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3716
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4994
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25291
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76929
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-540-PROX1_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16996
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19289
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBGCP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13737
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.374
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.541411
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4528
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25093
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0726
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11396
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
VCP-NPL4-UFD1 AAA ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.028
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4245
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3985
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6102
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2914
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10016
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5833
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1938
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_1_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
5748_NOP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.764857
K562_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159229
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.21202
PC-14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
GSE81193_1_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173197
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7683
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31936
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151797
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138785
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18616
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165205
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13084
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05553
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OV-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90444
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_20_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
8433_SRSF3_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16968
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46351
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03674
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236868
GSE112762,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04586
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149005
GSE146070_1_v_0_edem3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE75209,GSE75212_0_v_1_halofuginone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mean reticulocyte volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.15229
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_13_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147178
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23373
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52464
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35389
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147613_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6609
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137137_1_v_0_rcor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4655
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1892
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100552_PCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11578
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
2414_DUT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502913
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174843
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32576
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mean corpuscular hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.42218
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25195
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.46
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_8_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241031_0_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01848
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34303
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1122
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27528
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138862
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115752
A549_Fluorouracil_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135636
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62263
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7925
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137113
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03225
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221932,GSE222115_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26426
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5211
A549_M344_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01495
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.434
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03054
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.81
MCF7_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00837773
8157_SMC3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.540998
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95688_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2051
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4896
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6827