association	dataset	threshold value	standardized value
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3215
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.167
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1772
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4711
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05128
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604099
Gonadoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.203
hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.332121
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1596
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6115
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3506
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN017_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66984
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08497
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05911
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475812
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5108
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1393
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041793
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830743
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.797
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055818
cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.369997
Lymphangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
hsa-miR-181b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-4262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96377
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551298
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052611
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090268
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6511
CRCGN014_HEPG2_3H:N24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00073
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1156
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59626
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040824
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.632777
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-138	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4289
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6928
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1714
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59286
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	265.909
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0431
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8199
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06276
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068165
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2336
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9028
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.497321
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080799
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.03242
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0478
endoplasmic reticulum part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.213322
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086857
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0351
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2518
CRCGN013_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37193
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047495
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.077
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2974
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.96279
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.637
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830411
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041951
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5024
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76476
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15709
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990323
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66238
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216332
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.58
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.60424
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17598
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64571
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041542
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0435
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6556
PMC11285331-cd-23-0539_table_s4_suppst4.xlsx-Expression_of_candidate_drivers-Table_S4_Candidate_Resistance_Driver_Genes_in_ZNF397-KO_Cells_ZNF397	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81166
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7244
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079281
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040298
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298731
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9156
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060364
Hepatic veno-occlusive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2815
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9042
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105907
19074828-TableS4	GeneSigDB Published Gene Signatures	1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.45447
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66039
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9494
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41251
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.00363
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7819
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
hsa-miR-181d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10455
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.297651
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.36392
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16844
CRCGN017_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18767
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5543
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283545
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8666
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7531
GSE239768,GSE239769_1_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Hemocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65761
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7437
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2812
x-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.55114
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74395
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1709
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2895
MYC	ENCODE Transcription Factor Targets	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.650966
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5062
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.605
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16188
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3576
x chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.588037
myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170299
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.22
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0026
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33728
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39009
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21568
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.176
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.397
multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.261599
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05657
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0875
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5037
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
Apical plasma membrane urothelial plaque	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1368
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.206535
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
46,XY sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.35704
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039534
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5526
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.9775
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131062
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14703
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8042
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7709
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.0014
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37827
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8527
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
beta-thalassemia major	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1772
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.6137
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068246
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.43587
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5406
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98175
MEL-745A cl. DS19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4773
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069884
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14262
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830743
Endometriosis of ovary	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2856
sex chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.81624
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.217693
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.851
Complete androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049595
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446422
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4787
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043434
gemcitabine_homo sapiens_gpl96_gse6914	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054766
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12581
Hca-F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
hs27	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0087
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041637
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6947
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8061
CRCGN015_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84223
CRCGN011_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1263
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55133
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23173
Neuronal ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043377
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83738
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
gonadoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08873
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1019
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042356
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042862
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5315
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25077
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9347
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.701945
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.99945
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066714
bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160387
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.948
Seminoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52641
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4137
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.063
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47534
hsa-miR-181a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041985
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040148
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065814
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5071
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056573
TBK1_druginhibition_188_GSE53658	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.36176
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02294
nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289199
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Y-linked spermatogenic failure 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.394
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7235
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7736
x-linked disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.865912
CTCF	ENCODE Transcription Factor Targets	1.0	null
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53933
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2338
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9587
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.26
Peritubular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052125
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456442
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
hsa-miR-4653-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2807
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61578
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2692
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6449
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.190168
ct96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4619
hsa-miR-181c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39365
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06278
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.260538
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.31926
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060313
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14838
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.03
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7199
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046295
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5127
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054392
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051499
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045217
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4367
Inguinal canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
tc90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4471
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851811
Y-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.146
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CX-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66727
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.6009
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.18724
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4239
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7177
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3414
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6814
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9581
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55052
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052759
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28937
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.303283
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.436402
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.44762
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.585
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7313
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14654
hsa-miR-3921	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062382
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051209
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.12
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.201
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.954
Variably charged protein VCX/VCY1	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30614
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64544
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5618
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1528
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052485
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044501
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
MCM8-MCM9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.002
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74495
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4903
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.083593
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7678
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040848
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.963
y chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.546885
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051647
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086955
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9506
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45156
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9452
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2084
nucleolus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.205399
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.1
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8947
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	167.644
Boutonneuse fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.00049
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8547
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1579
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17615
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05276
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10421
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21831
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3894
CRCGN012_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12251
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
camptodactyly-arthropathy-coxa vara-pericarditis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.961
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
PRC_Partial Depletion_GDS3531_563_human_U2OS cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null