association	dataset	threshold value	standardized value
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
Mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
BRD-K60343011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25363
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.50167
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Ensemble_gene_ID_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77820593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07135
BRD-K37073485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38463
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3963
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.442
BRD-K63270352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25533
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25104
Adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.044
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
BRD-K23430405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37529
ECI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63949
Vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.22
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K22045035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33907
Collagen network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.937
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7362
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.902
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4239
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
gentamycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26861
Langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
Ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23079
Peritoneal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
Intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinal vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.46
Breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.886
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Arachnoid mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.534
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12395
Spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
protein-containing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.187
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8544
PMC11266089-Table3.XLSX-Fig1_Disease_targets-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29659
BRD-K01774461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31973
Integrin alphav-beta3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.779
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Tuberous sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0696
Striated muscle thin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77095
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4613
Mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9542
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36839
GSE130217_0_v_2_sesn2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
Common cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
VEGF-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.817
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21934
Lymphatic endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.317
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Extravillous trophoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45031
BRD-K65464785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09451
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16163
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.442
BRD-K06956443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0557
PMC8304542__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.879
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
BRD-A77697958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05865
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28961
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60364
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
Jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68956
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38455
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50759
PMC5425619-mmc6.xlsx-Supplementary_Table_IRF1_Change-TABLE_S6_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
Benign ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
Signal Transduction	Reactome Pathways 2024	1.0	null
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.602
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5711888__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.96
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23442
BRD-K11219023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20508
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86265
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91041
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10115
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.924
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47457
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
BRD-K43017905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85807
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
Filarial elephantiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5078
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
BRD-K33420995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.189
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49409947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10477
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17488
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71381
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.263
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83643
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8358
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7148
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86335
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
Myelomonocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
Alveolar cell type II	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAPGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1077
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78767
BRD-K26591929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88727
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48078
Gallbladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
Bleb	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
BRD-K77706833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02419
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33273
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61916
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-5.47582
Relaxin signaling pathway	KEGG Pathways 2026	1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
collagen-containing extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.481
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.9348
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93291
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.577
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.6186
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30343
T-24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83523
Lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.614
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.108
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42172
BRD-K27111500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0679
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
Vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.614
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.231
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48315
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
BRD-K29820234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56377
PMC12446642-mmc1.xlsx-Table_S7_Overlap_MR1E-5-Supplementary_Table7_Overlap_between_Cox_associated_proteins_and_MR-positive_proteins_with_a_MR_SNP-P_threshold_of_1E-5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60287661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06104
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.013
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.459
Heart ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
BRD-K20724649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11737
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38461
Pericardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CAAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28348
BRD-A96007399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77001
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6452
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19174
Placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
PMC9138619__F3a	PFOCR Pathway Figure Associations 2024	1.0	null
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76759
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5731
Marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.24
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0444
KS-IMM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
Subependymal glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
Pleural disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.135
Histiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
Chorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
Peripheral artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.787
Cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50761
Connective tissue benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37499
BRD-K99521908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1545
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03517
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25912
Vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.402
BRD-K45503385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13891
Schwalie et al.Nature.G4_Adipose tissue_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
Villous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.8644
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.736
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
Carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
Brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
adipose-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60661
BRD-K72835476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08707
Abdominal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
Ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
Chondrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4386
BRD-K43326597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68605
Solid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0423
PMC10869077__F9	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K92176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06698
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9741
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87247
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77673
Large B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09164
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44023
Soft body part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
Fibroadenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
BRD-K33705415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82621
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95412
M1 macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.514
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17921
Hereditary lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.408
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUDT21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80526
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.084
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
HMVEC-dLy cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
BRD-K81318113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39132
HPAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
Muscularis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	155.56
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02263
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41588
Cardiovascular organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46874
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62732
Gastroesophageal junction	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14585
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
Renal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Extravillous cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
BRD-K37403152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18645
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.602
Microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
Capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.562
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
Lymphangioleiomyomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.094
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41751
BRD-K22485649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0416
CRCGN015_MCF10A_48H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07315
BRD-A96308662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4251
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Breast ductal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
Bronchoalveolar lavage fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.453
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11418
BRD-K86491317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74871
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34995
Hodgkin's lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0327
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0549
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83647
Peritoneal mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9778
EPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86855
Spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.31
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
Periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.737
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0619
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10764
Blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.039
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34307
Chorioallantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.914
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.8615
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.667
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
OCRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23864
BRD-K85851814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19059
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
PI3K-Akt signaling pathway	KEGG Pathways 2026	1.0	null
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06011
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
BRD-K41141507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14342
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21357
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04719
Transitional cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
Submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
Uveal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49164
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Decidual stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0307
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
Respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.462
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.678
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2342
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19508
Umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.268
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83184
laminin-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
PTEN phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.463
BRD-K41327620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49476
Retinal ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
BRD-K70052888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21584
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.051
PMC10550586__F4	PFOCR Pathway Figure Associations 2024	1.0	null
cellular response to vascular endothelial growth factor stimulus	GO Biological Process Annotations 2025	1.0	null
Alveolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K03035008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2984
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1804
ZNF782	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41195
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.136
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.283
Ocular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
BRD-K75679095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35033
Uterine endometrial cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
BRD-K88543505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2112
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53746
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
Posterior cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.598
Prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.873
Telangiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06417
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58217
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90473
Filariasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27284
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
BRD-K76351135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69376
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.373
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5259
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
Muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.399
PTK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06892
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58008
KG-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7403357-41598_2020_69735_MOESM4_ESM.xlsx-24h_AV_Genes_Sig-FOSL1_is_a_novel_mediator_of_endotoxin_lipopolysaccharide-induced_pulmonary_angiogenic_signaling_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44518
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70397
BRD-K60780031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78064
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97782
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.354
Intussusception	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
Cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
BRD-K62967214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59032
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84863
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.274
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.298
GSE190316,GSE190324_6_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bone marrow stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91856
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71387
EAhy 926 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26409
BRD-K74694052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36599
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95414
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
BRD-K64055457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04266
Dura mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89957
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92729
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26069
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Deep inguinal lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
BRD-K53943097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85584
BRD-K32699895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46016
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33124
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0219
Stalk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.923
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0883
Hereditary lymphedema I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.237
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09837
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3316
MCF-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.43989
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.095
Bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02554
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56885
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28886
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04363234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88727
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9995
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1266
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.592
PMC8803621-mmc5.xlsx-54JIB-04genes_w_GATA4_motif-GATA4_Q3_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26786741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07524
secretory granule lumen	GO Cellular Component Annotations 2025	1.0	null
Head and neck squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
Germinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
BRD-K80923834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76348
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62047
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.32
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2033
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13933
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0507
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
GSE100102_4_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.373
BRD-K30053194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89483
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33455
BRD-K96284156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03172
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82375
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.495
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0699
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.183
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45288
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97204
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.188
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80881
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61736
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27909962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5284
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4042
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0238
BRD-K92018859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08802
Arterial blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89839
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
ARL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55874
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.001
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31454
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42201
Endocrine organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
HGC-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86586698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13867
Stigma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1659
PMC4838354-supp_gkv1491_nar-01150-met-k-2015-File011.xlsx-Differentially_expressed_genes-Differntially_expressed_PBX1_and_NOTCH3_common_genes_under_GSI_FC_1_3_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.11
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71105
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
Lung endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5193
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Integrin alpha3-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7241
EEF1AKMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82147
BRD-K47438870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11121
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43789
BRD-K75092094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0872
Meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2452
BRD-K97729706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13041
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
BRD-K84266230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30912
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42971
PMC4259415-oncotarget-05-10198-s002.xlsx-Sheet1-PPAR_Pathway_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
Heparanase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3311
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35596
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72936
Dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.857
PMC3217937-1756-0500-4-471-S1.XLS-Gene_Set-P53_targets_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
nitric-oxide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
BRD-K92210988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04234
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-x_TFEB_KOcon_VS_WTcon_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2013
Vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.05
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Diabetic macular edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.096
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.507
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4031
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62794454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37947
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.358
BRD-K93442068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00886
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7375
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65583
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08714
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20543
BRD-K66573697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1959
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
sprouting angiogenesis	GO Biological Process Annotations 2025	1.0	null
Vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.815
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9477
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64395
BRD-K43375231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52439
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
Langerhans-cell histiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
Mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Leukostasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.899
Tunica media vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01231
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.183
PMC11634769-44161_2024_567_MOESM3_ESM.xlsx-ST_7-Supplementary_Table_7_F-statistics_and_Rē_estimates_for_the_genetic_instruments_tested_in_cis-Mendelian_randomization_MR_analyes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24424
Thrombospondin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.963
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97968
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
DNAAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32494
Capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
PMC10311050-mmc2.pdf-65-NFIB_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36139
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.374
BRD-K53813421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1301
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40646
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.979
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0793
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6136
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0243
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.536
A549_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118214
BRD-K23793049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92978
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver sinusoidal endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
Oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3712
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10395
Uveal melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphangioleiomyomatosis cell(LAMcore)_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30946
Aortic valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
Perivascular epithelioid cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.254
blood-lymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97183
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
Sprout	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.167
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.689
Gaucher's disease type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
Porcine aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
Iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50076
Kidney angiomyolipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.66
GSE125153_2_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74795
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.837
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17857
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53279
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27695
Hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
PMC10977553__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26818
MITD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84647
Blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.407
GSE221004_1_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7616
Colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5175
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5436
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3656
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.146
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
Ductal carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.7
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55328
Mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.171
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44915
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4351
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04634
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.085
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
BRD-K48516290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00875
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40408
Hepatic artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
BRD-K35491869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94344
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66548
LoVo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
BRD-K28320832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1483
Hemangioendothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.029
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
PMC4259415-oncotarget-05-10198-s002.xlsx-Sheet1-CREB_Pathway_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.11
Adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0142
CAL-72 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
GSE100102_4_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastroesophageal junction adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
PMC5031867-mmc2.xlsx-RYTTCCTG_V_ETS2_B-GENE_SYMBOL_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
Bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93347
Leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pulmonary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
Smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.224
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79969
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Platelet activation, signaling and aggregation	Reactome Pathways 2024	1.0	null
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
PMC12446642-mmc1.xlsx-Table_S6_Overlap_MR5E-8-Supplementary_Table6_Overlap_between_Cox_associated_proteins_and_MR-positive_proteins_with_a_MR_SNP-P_threshold_of_5E-8_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34555
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5422
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
Cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.007
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51637
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70651
Venous endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.845
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73019
BRD-K98466889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06714
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31819
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89341
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.1236
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4139
PMC8755726-42003_2021_2958_MOESM7_ESM.xlsx-TWIST1_tumor_stroma_signature-Ensembl_ID_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24258
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Embryonic blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.398
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1503
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61403
MDA-MB-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7505
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47705
Capillary pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49747
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99654
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.288
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16493
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.141
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
LIVF001-005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14282
Heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.933
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.158
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9259
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1109
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85785
Artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.64
Head and neck squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6048
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66327
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41475
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
BRD-K78762661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42537
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00151
Esophageal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
induction of positive chemotaxis	GO Biological Process Annotations 2025	1.0	null
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03612
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13949
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
Trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.49
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9251
BRD-K03015524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67067
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Gene_name_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
Immunoglobulin complex, circulating	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
IFI30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97126
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34085
BRD-K33303625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15766
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.475
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
Glioblastoma multiforme cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
BRD-K46306128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9275
mp8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32628
Brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
Organelle membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.893
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29155
Low grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Lymphedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.928
BRD-K40602242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02499
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.655
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55131
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.526
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.252
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1387
GGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02932
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5005
PMC9941420-mmc1.docx-3-ZNF704_ZNF704	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4882864-40478_2016_323_MOESM16_ESM.xlsx-1_List_of_AP1_targets-Supplementary_Table_15_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.311
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
Endometrial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
GBC-SD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
Urinary bladder cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.222
PMC4498179-srep11671-s1.pdf-191-TAL1_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.923
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61987
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22425
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46695
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.111
Superficial inguinal lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
Plant oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
BRD-K56759808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24436
Vascular endothelial glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
Integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.898
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.12098
PMC8850399-DataSheet1.xlsx-Suppl_Table_4-Supplementary_Table_4_MR_results_of_VAT_to_90_proteins_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.347
BRD-K80779045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85454
Chorioangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
SK-MES-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21089
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0673
GSE114258_3_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tongue cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.512
Osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Lymphoid follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
Uterine cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25873
t62-spleen_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.12153
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
Chorionic villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
BRD-K76541957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09119
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.14
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6296
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.323
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
INKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53955
PMC6122955-elife-33947-supp2.xlsx-NY8_v_NY15_DE_Bru-seq-HNF1A-regulated_genes_Bru-seq_after_shRNA_in_NY8_or_NY15_cells_-_related_to_Figure_7A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78344
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Colorectal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Arterial endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.372
Adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.546
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
BRD-K78298277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39289
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9667
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0807
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03659
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
Endogenous progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.122
Angiomyolipoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.481
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
M2 macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
SUM-190PT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
Platelet alpha granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6944
BRD-K37331547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73472
BRD-K65137277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30392
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
laminin-9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9559
Hemostasis	Reactome Pathways 2024	1.0	null
Extracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.051
Parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.70142
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
MPT synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Benign vascular tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01904
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9581
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.798
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07706
BRD-K78889331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26784
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13804
BRD-K06148713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.345
BRD-K60339813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34738
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.349
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.259
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.348
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24416
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.6747
Corneal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5253
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37342
BRD-K00877314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49259
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.722
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
Focal adhesion	KEGG Pathways 2026	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-M34385771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13586
Background diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
PMC8554124-DataSheet2.XLSX-23-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A81552806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34587
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23597
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01177
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30507
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06526
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6042
Malignant cystadenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
EOMA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
BRD-K01083922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62317
GSE119564_2_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
Neovascular glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K53456628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40231
Skeletal muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4199
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Pericardial fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8558
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47365
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.613
Type III intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.894
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
GNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51225
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5742522-peerj-05-4214-s005.xlsx-Sheet1-Strabismic_medial_rectus_MR_vs_donor_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180631_1_v_0_yap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8056
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
Thyroid gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.343
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
BRD-K70978931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0482
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57797
BRD-K95788660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5456
Urinary bladder carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8849
BRD-K79494396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09287
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-LPS_vs_CTR-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
BRD-K25094041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14466
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2866
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.369
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63642
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85456301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06326
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2251
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE246195,GSE246305_4_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Integrin signaling	KEGG Pathways 2026	1.0	null
BRD-A03121430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12036
CRCGN015_MCF10A.WT.HP_24H:M18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71175
Secretory granule lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K09993756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90076
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.438
BRD-K46413323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77006
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.115
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20603
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3903
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
BRD-K93472147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14077
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74672
Macular holes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
Atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
Egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
Calcium signaling pathway	KEGG Pathways 2026	1.0	null
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
Cyst wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
Regulatory T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.709
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6053
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33462
BRD-K96493283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4825
BRD-K11436949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33278
BRD-K48383713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0074
BRD-K47283018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50851
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.813
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
Colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.113
Umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.739
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3243
Bone sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5471
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223241_2_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6053
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
Anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.178
M1 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7035
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.917
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
BRD-K53257131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4087
OFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30376
Signaling by VEGF	Reactome Pathways 2024	1.0	null
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70302
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0504
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97312
BRD-K15579005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4283
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04416
BRD-K91655763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61876
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3998
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
SAS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
Bronchopulmonary dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3472
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7163
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.534
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
Stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
PMC3102637-1471-2105-12-99-S2.XLSX-11_sigpathways_in_AA_P_0_001-Unnamed_39_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03474
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
CRCGN017_MCF10A.WT.HP_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19628
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
Semimembranosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
Papillary thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1854
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Integrin alpha1-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
BRD-K23886631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61858
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.447
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6144
Parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Proliferative diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
Abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.106
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2091
PMC9974099-jci-133-147087-s013.xlsx-Receptor_GSC__ligand_GBM-Ligand_expressed_in_GBM_CAF_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
BRD-A23434937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41045
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98873
BRD-K35792251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55725
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9931
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
vascular endothelial growth factor receptor binding	GO Molecular Function Annotations 2025	1.0	null
BRD-K94344234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48128
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61871
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25777
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
BRD-K99939253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33963
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Vitreous detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0943
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7453
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86544
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9883
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
NF-19-JL47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227192
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17187
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71965
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30344
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
Focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.736
BRD-K08233096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55817
Neuroendocrine tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
Breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.237
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
PMC9254480__F1	PFOCR Pathway Figure Associations 2024	1.0	null
platelet-derived growth factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.867
BRD-K16911140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73819
Bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.177
Mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.189
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4033
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43139
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50781
Brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
Nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
BRD-K67734449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24139
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.365
DX-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34421
regulation of mast cell chemotaxis	GO Biological Process Annotations 2025	1.0	null
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64339
TNF signaling pathway	KEGG Pathways 2026	1.0	null
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
BRD-K03341571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55278
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52462
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50386
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07809895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37636
Mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
High endothelial venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE4470_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84608
Vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.868
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89614
PI3K Akt signaling	WikiPathways Pathways 2024	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.67781
Dermal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20915
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
Mammary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8507
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07521
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	5.96986
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0862
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.703
Venous blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
Endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.289
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Malignant adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87341
SLC39A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03733
Endometrial stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
BRD-K79712504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87288
Colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0012
BRD-K61144709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00314
Intestinal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Extravillous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.628
Blood serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.104
BRD-K33151492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05516
Epithelial ovarian cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5311
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66833
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
Idiopathic interstitial pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0352
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58941
Papillary carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
Prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63673
Decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.051
Trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
BRD-K07496812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13484
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.536
BRD-K84054400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19669
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96322
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K01285236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42101
Uterine benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Phosphatidylinositol phosphate phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.468
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
BRD-K61134709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21047
Cystic lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96851
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Perivascular tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
enlarged thymus	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K22812176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4405
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Lymphoid interstitial pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
insulin-like growth factor binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.651
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84519
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06019
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PROB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65775
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07334
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5084
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2028
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88834
Signaling by Receptor Tyrosine Kinases	Reactome Pathways 2024	1.0	null
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
Mesenchymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12837
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02854
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.902
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
Venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.818
Platelet alpha granule lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96946
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8802
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30328
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43574
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
Glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
Matrix fibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
vascular endothelial growth factor signaling pathway	GO Biological Process Annotations 2025	1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65155
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4521
Intrahepatic cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.244
BTBD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55808
Ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Microspike	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
Lung squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94854
Perivascular astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16035
BRD-K64591035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15965
BRD-K03546460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40025
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
Hecv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05511
BRD-K00191683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23888
Bronchiolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
pre-malignant neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
Organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HUVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.267
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.7381
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58713
PMC12092893-12672_2025_2715_MOESM1_ESM.pdf-7-TCF23_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
BRD-K23956364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24404
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
Endometrioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67954
Large luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.326
Vascular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58665
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46039
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
Vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.714
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45190659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25142
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39416
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39011
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.881
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43168
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1127
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.184
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.986
Muscle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.599
Root nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.803
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95195
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29186
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
Congenital chylothorax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.03
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
CRCGN015_HEPG2_48H:B05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21591
Epithelial stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.022
Chorionic plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Angiomyolipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.583
Dorsal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87075
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68806
BRD-K56013842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06926
Head and neck cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
B-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01599
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.567
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
Cell wall-bounded periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
Complex of collagen trimers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
Heart endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08929
Pulmonary artery endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376501
3asube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36826
GSE239457_1_v_0_rasa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
Cervical squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2064
BRD-K78218619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29005
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9274
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9528
MALSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04452
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha5-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28113
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
BRD-K65868510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06901
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.348
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81011
PMC2768459-6605275x5.xls-Hoja1-Supplementary_Table_S2_Differentially_expressed_genes_within_the_ESR1-negative_BRCA1_tumors_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57153
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphangiosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
Clitoral smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.052
Pseudopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81585
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
Mesenchymal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.883
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14386
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.302
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
GSE196699_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gastric ulcer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47631316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77643
Lymphangioleiomyomatosis disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.942
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.069
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
Severe pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
ITPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
Vascular bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
Activin AB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.914
Tracheal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
PMC11474168-ccr-23-1242_supplementary_table_s4_suppst4.xlsx-AR_tumors_genes-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67518
Hypopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2526
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
graft-versus-host disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
BRD-K03141963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15155
Germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.159
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48368
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
Lymphotoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.12152
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2374
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48059
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.037
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09265
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.843
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41798
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
External encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.693
Activin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
Cystadenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60433
TRIM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36486
GSE165647_5_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.787
LAN-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Lymph vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.439
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74303
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25566
Dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.032
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23608
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.977
Pelvis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
Ventral aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
Inflammatory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.187
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7147
BRD-K38081867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35411
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33715
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1306
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
lymphedema-distichiasis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
receptor ligand activity	GO Molecular Function Annotations 2025	1.0	null
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33334
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.937
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.43313
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
Lymphatic endothelial cell_Lymph node_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.7111
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90997
BRD-K47903820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37595
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5876
BRD-K64824710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19605
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2907
PMC11923433-BLOOD_BLD-2024-025618-mmc2.xlsx-S3_Specific_genes_in_CEBPA-dm-Supplemental_Table_3_The_subtype-specific_enriched_marker_genes_in_CEBPA-dm_subtype_patients_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Clara cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
Hemangioendothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4838354-supp_gkv1491_nar-01150-met-k-2015-File010.xlsx-ChIP-seq_defined_target_genes-PBX1_and_Notch3_common_target_gene_list_621_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37371
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
Smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.345
Basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Decidual cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53244
Venous endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.789
BRD-K02100640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48147
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87114
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36181
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76924
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66848
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
Arterial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
Pigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.586
Uroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
BRD-K27109474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15991
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40257
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Focal adhesion	WikiPathways Pathways 2024	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.9298
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52042
Tonsil cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27153
Arteriovenous malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
BRD-A54389315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35243
GOLGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56514
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
BRD-K72808738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00619
BAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6202
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.116
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.661
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.537
Pericardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
BRD-K54212583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32576
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.272
BRD-K84874502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19348
Mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.321
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7738
BRD-K06577881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26311
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
platelet alpha granule	GO Cellular Component Annotations 2025	1.0	null
Ascites	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.701
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.07
BRD-K20428189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39745
B16-F10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4874
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16095
SGC-7901 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.061
Hepatic vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.145
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.176
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
Lung non-squamous non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.067
Respiratory system_CT1_alveolar type 1 fibroblast cell	HuBMAP ASCT+B Annotations	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
Cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.243
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47065
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
Phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.293
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Telopode	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.509
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0558
platelet alpha granule lumen	GO Cellular Component Annotations 2025	1.0	null
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
UBE2Z	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8093
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31408
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9067
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56682
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53764
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9192
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96355
ZNF296	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59604
PMC10945549-elife-91472-supp1.xlsx-Table_S1_Fold_change-Supplementary_File_1_Fold_change_of_average_cytokine_level_in_LPS-treated_macrophage_compared_to_control_PBS-treated_macrophage_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.802
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9123
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
MTURN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40492
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.165
Retinal vascular occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99994
Uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.845
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.606
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86572
Severe COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.45101
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3267
Uterine wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43188
Integrin alphav-beta5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.1
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46176
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
BRD-K55381473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4708
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
laminin-14 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.903
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2548
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
BRD-K11730256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36342
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.5771
PMC5031867-mmc2.xlsx-RYTTCCTG_V_ETS2_B-PROBE_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
Bladder carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
Peripheral blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.032
Integrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.021
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17539
CRCGN009_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32655
BRD-K80467627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06845
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
Uterine leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
Squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64522
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-LIN28A_LIN28A	Rummagene Transcription Factor Associations 2026	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4446
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.096
Aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
BRD-K05462252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03886
Inferior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
BRD-K29838935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17552
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3524
Epitheloid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06839
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8439
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63749
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
interleukin-23 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.056
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
Integrin alpha4-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.505
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52671
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6293
BRD-K81623965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15236
Fibrinogen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.375
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1393
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71627
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.395
TRAFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57853
Capillary hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
Pulmonary edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00541
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.12
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
Kuhnt-Junius degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.232
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05124
Subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.441
Primitive neuroectodermal tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
CRCGN008_HEPG2_24H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46285
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5314
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.51
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4822
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9946
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
Alveolar sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
ZNF672	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20252
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35707
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3997
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
Invasive ductal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
CSF1-CSF1R complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48836
Acne	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
MDA-MB-468 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
vascular endothelial growth factor receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
Gorham's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64546
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64549
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.715
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9034
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
VEGF ligand-receptor interactions	Reactome Pathways 2024	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4917
interleukin-27 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.096
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1781
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
Integrin alpha6-beta4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
Nuclear dicing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
Heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
Thyroid follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1354
PMC7481169-277_2020_4194_MOESM9_ESM.xlsx-RUNX1_R174L-RUNX1_R174L_mutant_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08511
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
platelet-derived growth factor receptor binding	GO Molecular Function Annotations 2025	1.0	null
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
Severe nonproliferative diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
CRCGN008_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4671
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42867
PMC5013636-ncomms12601-s5.xlsx-AP1-Groups_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75458
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50272743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39909
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04659
Breast carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
PMC7788918-13058_2020_1379_MOESM2_ESM.xlsx-S9-S9_limma_voom_differentially_expressed_genes_ESR1_depleted_recurrences_vs_matched_primaries_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57589
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
Root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2452
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96163
PMC12630751-41540_2025_602_MOESM2_ESM.xlsx-Sustained_Angiogenesis-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Generalized lymphatic anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
BNL CL.2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
t58-heart_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.00994
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10373
Bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.528
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Retinopathy of prematurity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83222
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2102
Gallbladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.324
Extracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.047
COLO-699 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
PMC11269579-41598_2024_67843_MOESM1_ESM.pdf-13-HES3_HES3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19014823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94946
Hereditary hemorrhagic telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
BRD-K54986816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8914
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
Amniotic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
Anterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.705
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6782
BRD-A69383366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51298
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.129
BRD-K21000135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31624
Uterine fibroid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.047
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K10105458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16217
Inhibin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60934
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93944
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39808
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
Blood platelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.028
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61215
Thyroid gland medullary carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08418
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.424
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7436
Tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.465
Allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15013
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
BRD-K56024344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41509
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
Vesicle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02105
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29949
B16-F1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
Internal iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
positive regulation of mast cell chemotaxis	GO Biological Process Annotations 2025	1.0	null
CDK18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39105
Stromal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.701
Brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
Mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.837
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08014
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.4404
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
PMC12823428-43587_2025_1018_MOESM3_ESM.xlsx-ST12-Supplementary_Table_12_Main_mendelian_randomisation_results_of_plasma_proteins_on_delirium_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
VEGF binds to VEGFR leading to receptor dimerization	Reactome Pathways 2024	1.0	null
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93528
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8838
Endophthalmitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
Aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84232
GSE203308_7_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8055
ARL4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00681
GSE157904_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
SKOV-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
AGE-RAGE signaling pathway in diabetic complications	KEGG Pathways 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83202
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.001
Cardia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90632
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
PMC12529848-12967_2025_7217_MOESM3_ESM.xlsx-Table_S4-Table_S4_Associations_of_genetically_proxied_proteins_with_risk_of_atrial_fibrillation_by_MR-SPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
WDR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24509
Mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.424
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6719
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6645
BRD-K52406139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0571
Central nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
PMC6562438__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.395
Osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.727
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29064
vx2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72031
Primary spontaneous pneumothorax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.963
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.759
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5008
Corneal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
HMC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1688
BRD-K75495990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11251
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-KIM_MYC_AMPLIFICATION_TARGETS_UP_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.313
BRD-K60255752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3546
Umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
Squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
BRD-K28563387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10868
Mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.347
Anterior cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
Ras signaling pathway	KEGG Pathways 2026	1.0	null
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37348
PMC11936835-41562_2024_2078_MOESM4_ESM.xlsx-Supplementary_Table_10-Supplementary_Table_10_MR_analyses_of_proteins_and_protein_modules_on_social_isolation_and_loneliness_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52842821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25376
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.837
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3333
Intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1887
ACHN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.052
HaCa-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51413
BRD-K98251998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69175
PMC8016646__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.599
BRD-K90239051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21786
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.213
Lewis lung carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.043
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
PMC3706521__F4	PFOCR Pathway Figure Associations 2024	1.0	null
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99969
Neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.057
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82029
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07272
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45432
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40513
TORC2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.291
Pleura	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastric adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11997
Peritoneal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
PMC3195192__F2	PFOCR Pathway Figure Associations 2024	1.0	null
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88272
Angiosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51995
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02328
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43434
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55053
TSC1-TSC2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.445
Fibroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
growth factor activity	GO Molecular Function Annotations 2025	1.0	null
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
Renal cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.139
albendazole-oxide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37831
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65296
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2024
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.166
BRD-K17574409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08147
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9176
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57729
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27043
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
BRD-A00522887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37168
CRCGN014_HEPG2_3H:D16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01287
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.8423
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Corneal neovascularization	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.243
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.601
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52009
BRD-A99644411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16676
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
HSC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Dental pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
Cystadenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
abnormal heart morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Bone marrow stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
BRD-K08723967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14836
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.739
Gilin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32465
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42306
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7648
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87156
BRD-K71032892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05998
BRD-K15863674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10473
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
Dynein axonemal particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9006
Tek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.593
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0685
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43074
BRD-K17384993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31185
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.839
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48191
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.032
Dry eye syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
Lung disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.941
BRD-K29178949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28904
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
Odontoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6163
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
SUM-149PT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
alphaV-beta3 integrin-EGFR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
NSMCE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33054
EBC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1553
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.362
Spindle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
BRD-K82784817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39779
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89704
Alveolar wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.461
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10040389-mmc7.xlsx-URs_IMIDs_SP1_6-UR_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
Leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
CRCGN017_MCF10A.WT.HP_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11458
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7474
Growth factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.777
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.021
BRD-K37708631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23819
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7354
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12699
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88683
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34981
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81683
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24051
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5711888__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.015
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2838
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
BRD-K87385385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40654
Blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.67
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rap1 signaling pathway	KEGG Pathways 2026	1.0	null
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
Peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.871
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.275
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94995
Gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
Myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
Tunica externa vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.593
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53081
BRD-K86104966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05087
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Cholangiocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
Central retinal vein occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
Serous cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7176
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07081
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41594
BRD-K29383520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00731
Uterine leiomyoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.009
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13466
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
Bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66801
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
BRD-K77264557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17065
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
Mural cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.924
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
PMC9974099-jci-133-147087-s013.xlsx-Receptor_GBM__ligand_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
BRD-K28601178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56731
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24906
Wound fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
BRD-K49866472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03279
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
Lacrimal apparatus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.167
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79144
BRD-K57096799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50762
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97542
ELT-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
BRD-K84724939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06801
PMC8944338__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2503
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06794322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5468
Pleural mesothelioma	WikiPathways Pathways 2024	1.0	null
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN008_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0598
Body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.474
Vasculature	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.767
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35915
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16364
TOMM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7393
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34945
ASTRA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73731
Corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.435
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.677
Alveolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66098
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4103
interleukin-35 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04305
Pathways in cancer	KEGG Pathways 2026	1.0	null
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9143
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18095
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90655
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
Histiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
Chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
Pulmonary embolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13388
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93637
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.617
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.408
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3227
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
BRD-K55841827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19616
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.3832
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65975
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.291
BRD-K04257723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28722
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55584
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.907
Microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27139
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62805
Lymphangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
BRD-K28733696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0431
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06445
Medulloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.919
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23998
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58902
Gall bladder cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
Activin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
chrX_15534056_T_G_b38	GTEx eQTL 2025	1.0	1.18499
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01611
Aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.43
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.4444
Esophagus adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9921
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
BRD-K92736140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39973
Endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.115
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6403
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63321
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00918
Tongue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3696
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2926
Inferior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
Female reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
enlarged heart	IMPC Knockout Mouse Phenotypes	1.0	null
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91906
VTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57363
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76293
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
Retinal vein occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.594
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
Tenascin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.709
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21915
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.735
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
In situ carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8185
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.25
CRCGN011_HEPG2_24H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00765
ZNF324	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93555
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60358
BRD-K42084582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3273
Response to elevated platelet cytosolic Ca2+	Reactome Pathways 2024	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57862
Alveolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.228
CRCGN008_HEPG2_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21455
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4286
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09136
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.381
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2681
Gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
Anal canal squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02684
Bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
PMC6580124__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01749
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_11_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4163
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1526
Corn silk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
Kaposi's sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
ro82w1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
GSE114232_10_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesenchymal stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25826
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
STYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78211
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.128
vascular endothelial growth factor D levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
BRD-K10269761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31737
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22388
BRD-K83082136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16817
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7776
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
PMC8755726-42003_2021_2958_MOESM7_ESM.xlsx-TWIST1_tumor_stroma_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.989
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Follicular thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2977
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
FM3A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
Gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
GAPDHS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46245
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.824
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88304
Subependymal giant cell astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
Pneumothorax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.362
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62501
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72023
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14122
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1935
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.474
tm94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Immune infiltration in pancreatic cancer	WikiPathways Pathways 2024	1.0	null
Macular retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pericardial effusion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
BRD-K13445266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49865
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.86002
GTEx Brain 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	8.73326
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.304
PMC12169532-pone.0325700.s010.xlsx-Table_S4-Table_S4_List_of_genes_that_upon_knockdown_KD_led_to_transcriptional_signitures_similar_to_the_input_DEG_set_of_CRC_or_LIHC_and_their_KEGG_enrichment_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25335
CACNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86941
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4309
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
Esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
PMC8836812__F3	PFOCR Pathway Figure Associations 2024	1.0	null
IgG immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.942
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73039
BRD-K47883435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10016
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6219
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.289
BRD-K07790303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38138
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.536
Aortic arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
BRD-K36134372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30173
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.097
Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.409
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.518
adipose-derived stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
Basement membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.456
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04939366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1477
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9598
BRD-K99383477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24662
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80248
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
HMGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00017
positive regulation of positive chemotaxis	GO Biological Process Annotations 2025	1.0	null
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91411
Seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.95
BRD-K81954791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01374
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.459
Hennekam syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
BRD-K80816131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38071
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
Lewis lung carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.093
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09695
Sebaceous gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Vitreous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
Extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1221
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81943
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
Myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
Integrin alpha9-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.888
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8478
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42129
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37451
TSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.119
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89202
Umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.092
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11926
Heart valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
Yolk sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2622
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
Fallopian tube cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6063
BRD-K58955712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26447
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35075
Weibel-Palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.6571
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1718
Umbilical cord blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
Papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.095
Mesenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.819
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15976
Sc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50435683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27792
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46644
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.875
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38419
Endoplasmic reticulum-plasma membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.994
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.185
Lung adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4759
BRD-K80233876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91713
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22724
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.571
BRD-K98468968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50121
Oropharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.187
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.088
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78314
BRD-K81921806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12361
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.977
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
Thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.544
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09588
FAM43B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.451
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.91
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12436147-41380_2025_3032_MOESM1_ESM.xlsx-ST2-Supplementary_Table2_Blood_pQTLs_that_were_selected_as_genetic_instruments_for_MR_analyses_UKB_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7093422__F6	PFOCR Pathway Figure Associations 2024	1.0	null
ELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
Cardiac Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
BRD-K10372036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31478
GSE111035,GSE111040_8_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28146
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27535
Caki-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
GSE153124_4_v_0_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
positive regulation of leukocyte chemotaxis	GO Biological Process Annotations 2025	1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179031_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
BRD-K19770687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98788
Myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
BRD-K33951208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43969
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2161
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4488
PMC11748740-41598_2025_85338_MOESM1_ESM.xlsx-Table_S2-Table_S2_The_cis-pQTLs_Pass_Instrumental_Variable_Selection_Test_for_Primary_MR_Analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Corneal ulcer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
BRD-K83667863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12113
Myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.911
Gallbladder carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72652
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10494
BRD-A27844016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44743
Rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
Arterial endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
Diaphragm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
Extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.618
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4281
Focal adhesion PI3K Akt mTOR signaling	WikiPathways Pathways 2024	1.0	null
BRD-K99380757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58793
BRD-K84879982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35058
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56889
Kidney benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.447
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5837
Blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.022
Breast adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14188
Galectin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
Orbital disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
Keratopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.27
Fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
Urogenital ridge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.298
BRD-K35829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44101
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21981
BRD-K79152256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17105
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86036680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01048
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Hydrocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Calu-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79251
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4176
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67369
Angioblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.966
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
BRD-K93806272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18048
Gall bladder cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09374
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
BRD-K01627964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70318
Bone benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
GSE221004_1_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22322
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84861
BRD-K91419355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14057
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.666
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37712
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53248
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
BRD-K72296840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57922
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.687
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6274
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8624
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
BRD-A64849281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48419
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
Uveal melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48373
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.917
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
BRD-K56836463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13785
Breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9925
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33817
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
Artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.248
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04181
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27839
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
Extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.713
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9456
shikonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00796
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.026
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28775
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55789
Prostate adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.829
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6045
Osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytoplasmic vesicle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92968
GTEx Thyroid 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-4.89013
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2653
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
Cardiovascular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
Mast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
Microvesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9658
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59787
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8244
gg87	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Chondrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26435104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32343
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.031
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88402
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31715
Microvascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.984
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7933
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4732
BRD-K95710843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01579
Adult respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
Parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
Lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.814
BRD-K47878187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00854
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1107
BRD-K48213854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5756
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal thymus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Fibronectin fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.323
Subcutaneous tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
Cancer pathways	WikiPathways Pathways 2024	1.0	null
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36626
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05045
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17252
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
Lymphocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Fascia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
FANCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.622
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73596
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.099
HEK-293-EBNA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
laminin-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
STMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32284
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2204
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07685
Pericyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.39
BRD-K30264389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46531
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
Connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.563
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0042
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Elephantiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
GSE129725_4_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plant secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
ANKRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39644
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.84696
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33661
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08175
Syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
cell surface receptor protein tyrosine kinase signaling pathway	GO Biological Process Annotations 2025	1.0	null
Internal carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47714
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
Coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
BRD-K54577741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25737
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Birt-Hogg-Dube syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.064
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
T cell modulation in pancreatic cancer	WikiPathways Pathways 2024	1.0	null
Filopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.57
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
Musculoskeletal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
MAPK signaling pathway	KEGG Pathways 2026	1.0	null
BRD-K53936012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19898
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Interstitial cell of Cajal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
Myofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.949
BRD-K93691156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07341
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
BRD-K12867546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47201
Esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
BRD-K36743230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28635
Pleural cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.977
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytokine receptor binding	GO Molecular Function Annotations 2025	1.0	null
Conjunctival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
Tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.461
BRD-K14266419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31661
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68825
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.17
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55517
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06245
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34724
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16394
BRD-A37645929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61523
BRD-K21648400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03723
BRD-K11840410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50401
FZD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87386
SMAD protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
Uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
Respiratory system_CT1_alveolar type 1 fibroblast cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
PMC11634769-44161_2024_567_MOESM3_ESM.xlsx-ST_8-Supplementary_Table_8_Steiger_filtering_results_for_protein-disease_pairs_tested_in_sensitivity_cis-Mendelian_randomization_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40413
PMC3488236-supp_gks789_nar-02597-c-2011-File013.pdf-43-ATF3_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.34797
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68799
BRD-K05050883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3173
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9166
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10054
Lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5235
Myofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.204
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02194
Terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46454
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9426
GSE178255_3_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62631
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.471
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0616
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33686
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29368
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98622
BRD-K69082321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21898
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05824
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.603
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4812
KCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30216
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.074
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
NCI-H661 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
Retinal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
Sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68542
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.001
HMVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
SVEC4-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
GTEx Brain 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	6.04889
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50587
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7214
Renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.177
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23431
BRD-K77069371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12259
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
Uterine adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
Female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.295
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37257
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
Barrett's esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
PMC5755497__F8a	PFOCR Pathway Figure Associations 2024	1.0	null
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
Gastroesophageal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
Renal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51673
Limb ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
PMC5742522-peerj-05-4214-s004.xlsx-Sheet1-Strabismic_medial_rectus_MR_vs_donor_MR_AND_strabismic_lateral_rectus_LR_vs_donor_LR_experiments_COMBINED_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
Microinvasive gastric cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0279
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90188
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal stromal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12486367-Supplementary_Data2.pdf-353-EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
Adenosquamous carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
Subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
Brain endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
Platelet degranulation	Reactome Pathways 2024	1.0	null
Squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-DANG_REGULATED_BY_MYC_DN_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Mucositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.3806
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
growth factor receptor binding	GO Molecular Function Annotations 2025	1.0	null
Breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.879
BRD-K83270526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01561
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17754
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97064
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
PMC5819186-13040_2018_163_MOESM3_ESM.xlsx-Lung-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1065
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.805
BRD-K54247106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12587
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06719
Thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.375
Extracellular exosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.897
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
BRD-K76921877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08867
PMC9334849-Table_3.xlsx-subcutaneous_adipose_tissue-D1_VS_D9_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75293299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10778
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8611
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1493
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
Hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
BRD-A63503250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27986
Fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.39
Inflammatory breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04243
BRD-K69744558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0595
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59702
BRD-K15322427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23709
PMC10649670__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Endothelial progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.122
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35405
BRD-K47599758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37765
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.734
Follicular dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
chemoattractant activity	GO Molecular Function Annotations 2025	1.0	null
Blood clot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1369
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15865
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
PMC10778864__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20047
Gastroesophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5208
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9611
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peritonitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.799