association	dataset	threshold value	standardized value
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UC-00-QA88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256166
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16582
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24018
BRD-A81392774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24847
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Lapatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149898
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.49029
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03208
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53094
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30436657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26271
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49526793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16055
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.392775
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36791
PMC5638334__F10	PFOCR Pathway Figure Associations 2024	1.0	null
A549_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180706
SCARB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968204
furazolidone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54602
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879506
CRCGN017_MCF10A.TP53.M_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37025
Cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.814
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909039
HCC1954	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.88294
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.66417
Lung adenocarcinoma_LUAD_TCGA-86-8054-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EEF1A2	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4278335__F4	PFOCR Pathway Figure Associations 2024	1.0	null
SARS-CoV-2 Infection	Reactome Pathways 2024	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89087
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
A549_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156442
K562_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186297
Platelet alpha granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210283
RAB3GAP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960021
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A4FUK	CCLE Cell Line Gene CNV Profiles	1.0	2.5488
MTA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.00469
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-581	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLDA2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9492
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
hsa-miR-100-5p	MiRTarBase microRNA Targets	1.0	null
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15599
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
involving	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7478_RPL7L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.503657
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231907
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18911
FLII	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03175
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45526
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2288
endosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.624355
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213688
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-A59J-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
REPS1	Pathway Commons Protein-Protein Interactions	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67332
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895859
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81637
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63169405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57686
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19543
BRD-K73149920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15048
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF7_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SSBP1	Pathway Commons Protein-Protein Interactions	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_3H:G08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04334
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54374
K562_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178283
abnormality of myeloid leukocytes	HPO Gene-Disease Associations	1.0	null
salsolinol-4232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042074
COLO792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64347
BRD-K77541177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4208
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pramocaine-3811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane docking	GO Biological Process Annotations 2015	1.0	null
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952387
MCF7_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182936
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921917
SGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08848
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.78533
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24429
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZP-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39068
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00343
plastid-encoded plastid RNA polymerase complex A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
K562_Alendronate sodium trihydrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0207581
uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cytostome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.198
A549_Alisertib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145388
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24021
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03674
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Alendronate sodium trihydrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168136
CDC23	Pathway Commons Protein-Protein Interactions	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40693
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of immune system physiology	HPO Gene-Disease Associations	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_287_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	1.00733
EMC-BAC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.9512
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167729
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37933
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287279
Pretectal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27536
TM9SF1	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38485
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423741
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
A549_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141008
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-0.85145
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
CP-690334-01-4558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9094
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
PTP4A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19039
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870252
CCSER1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526717
OSBP	Pathway Commons Protein-Protein Interactions	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9459
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721584
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25841
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015812
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05645
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82809
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.63672
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537956
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89542
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07274638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15224
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SW1463	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44012
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO6	Pathway Commons Protein-Protein Interactions	1.0	null
Organelle subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.949
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26225
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98814
ARL15	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989095
aztreonam-5110	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188617
BRD-K93472147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09492
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tetrahydropalmatine	CTD Gene-Chemical Interactions	1.0	null
Red nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06095
MCF7_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164996
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
neutropenia, severe congenital, 5, autosomal recessive	OMIM Gene-Disease Associations	1.0	null
BRD-K66352426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12705
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902757
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K37961770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55124
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264011
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15823
CRCGN017_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.338
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40759
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.52117
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MCF7_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159761
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986109
A549_Bisindolylmaleimide IX_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166224
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.098042
SARS-CoV-2-host interactions	Reactome Pathways 2024	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
SMARCA4	ChEA Transcription Factor Targets	1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZR	Pathway Commons Protein-Protein Interactions	1.0	null
IRF9	Pathway Commons Protein-Protein Interactions	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
other organism	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.184241
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39641
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
BRD-K09528868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04945
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM25	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Tucidinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0103081
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950634
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of cells of the erythroid lineage	HPO Gene-Disease Associations	1.0	null
CLPB	Pathway Commons Protein-Protein Interactions	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
K562_Givinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154534
GOLPH3L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41438
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08881
A549_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018448
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.273
Golgi transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.711
TM6SF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519939
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9675280-12950_2022_317_MOESM3_ESM.xlsx-siPAD2_LPS_vs_siCON_LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04031
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16392
Hemostasis	Reactome Pathways 2014	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851936
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coelomic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
BRD-K71537579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0586
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.998033
CECR5	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60454544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0379
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74606
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905621
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149035_7_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEF2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_MK-0752_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153989
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68386
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COPI-coated Golgi to ER transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
CHEK1	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5088
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.56788
SARS	Pathway Commons Protein-Protein Interactions	1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
CD302	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00479462
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2698
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0259237
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
537_ARPC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.502349
MYOD1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14263
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26406
BRD-K10781609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51772
PMC4519954__F13	PFOCR Pathway Figure Associations 2024	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90925
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6166
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRAS	Pathway Commons Protein-Protein Interactions	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00662496
abnormality of humoral immunity	HPO Gene-Disease Associations	1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37732
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03519
A549_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211986
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0263216
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062402
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
17894856-SuppList2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877373
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35799
BRD-K16780806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24523
Perturb_6027_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.55481
USP9X	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
BRD-K06310280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17047
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3178
JAK1	Pathway Commons Protein-Protein Interactions	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887667
syntaxin-6-syntaxin-16-Vti1a complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01218
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936094
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4587
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12989
KRT19	Pathway Commons Protein-Protein Interactions	1.0	null
ALDOC	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HGS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40630587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23413
NEDD1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49292348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0137
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.90208
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1393
BRD-K89687904_PKCbeta inhibitor_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BIN1	Pathway Commons Protein-Protein Interactions	1.0	null
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLR21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56332
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.932506
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279876
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Extramedullary Hematopoiesis	DisGeNET Gene-Disease Associations	1.0	null
SH3GLB1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2122 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84774
BRD-K19534880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66507
compartment	GeneRIF Biological Term Annotations	1.0	null
MCF7_SRT1720 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151709
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23007
Dsl1/NZR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
SIGMAR1	Pathway Commons Protein-Protein Interactions	1.0	null
OSBPL11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68318
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240932
BRD-K44932450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00845
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.20298
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-56-JY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250008
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917146
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31934
Root quiescent center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906507
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43631
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDX1	ChEA Transcription Factor Targets	1.0	null
ARL6IP1	Pathway Commons Protein-Protein Interactions	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.20378
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30693
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hematopoietic stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70316
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
propidium iodide-5803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141809
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00543
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	2.18906
BRD-K86330848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01511
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29118
ABI1	Pathway Commons Protein-Protein Interactions	1.0	null
GNAO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601609
PMC3500769-srep00875-s3.xls-GATA3-Time_1_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.33836
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
heliotrine-4277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12472
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1535
VPS39	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852907
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Andarine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191284
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95687
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193992
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_112_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46865
A549_Ellagic acid_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190394
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42C-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEX101	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584025
MCF7_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179637
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0854
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48367
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dyskeratosis congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23028
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.617423
P31-FUJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77369
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
K562_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164905
BRD-K20069402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24882
mantle zone of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22434
K562_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218203
MCF7_Motesanib Diphosphate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254774
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941879
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
Measles Chicago-1_6Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15664
SIX5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66284
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90149
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.867015
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.717
albendazole-7164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TRIM28	ENCODE Transcription Factor Targets	1.0	null
NCIH1568	CCLE Cell Line Gene Expression Profiles	1.0	1.48066
A549_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231592
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Recurrent Infections	DisGeNET Gene-Phenotype Associations	1.0	null
Hecv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.544
MYH10	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3661
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mebendazole_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0207403
JHH4_LIVER	CCLE Cell Line Proteomics	1.0	2.8538
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.765051
clinical modifier	HPO Gene-Disease Associations	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95061
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
K562_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171397
MCF7_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0297716
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868354
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.383102
PMC10337103-13046_2023_2747_MOESM2_ESM.pdf-25-ENSG00000137504_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
all	HPO Gene-Disease Associations	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.60703
VCP	Pathway Commons Protein-Protein Interactions	1.0	null
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
697	DepMap CRISPR Gene Dependency	1.0	2.00838
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29595
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4334
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846034
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.12388
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92722247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54017
MCF7_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165899
RIN1	Pathway Commons Protein-Protein Interactions	1.0	null
Increased Antibody Level In Blood	DisGeNET Gene-Phenotype Associations	1.0	null
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.678788
MCF7_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110168
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.81813
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM17_02_100	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58803
CRCGN010_HEPG2_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53554
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16315
FBLN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615238
A549_Maraviroc_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185717
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RA-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34827
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11397
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.237
Pollen tube tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARFRP1	Pathway Commons Protein-Protein Interactions	1.0	null
A549_BMS-754807_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150398
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07388
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04104
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07239
A549_FLLL32_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157309
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48005
Endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.479
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13614
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86349956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60244
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59447
BRD-K91387865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28479
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3225
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27287379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50102
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAM	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35138
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268349
STX7	Pathway Commons Protein-Protein Interactions	1.0	null
SNX9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Sodium Phenylbutyrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191495
MCF7_Pelitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111454
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29017
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91336
PTPN9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
A1207	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69445
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-E2F1_UP_V1_DN-Ensemble_gene_ID_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC202	CCLE Cell Line Gene Expression Profiles	1.0	1.59731
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16207
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.81061
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11029
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.885
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08916
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	1.83216
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.968111
MCF7_ENMD-2076 L-Tartaric acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0102372
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29521
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96668
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
TBC1D15	Pathway Commons Protein-Protein Interactions	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355393
phenacetin-2471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDK2	Pathway Commons Protein-Protein Interactions	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.05316
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3500769-srep00875-s3.xls-FOXA1-Time_1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890935
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8384
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887223
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60516
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16104
ap-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160658
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397675
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2683
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
MAFF	ENCODE Transcription Factor Targets	1.0	null
hvps45	GeneRIF Biological Term Annotations	1.0	null
CTSD	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14451397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19781
CRCGN016_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00772
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endosome membrane	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833435
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL5A	Pathway Commons Protein-Protein Interactions	1.0	null
TELO2	Pathway Commons Protein-Protein Interactions	1.0	null
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15297
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4278335__F4	PFOCR Pathway Figure Associations 2023	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180271
abnormality of erythrocytes	HPO Gene-Disease Associations	1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96262
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22756
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10055
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05467
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860199
12393420-Table1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K23404017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11976
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56478
BRD-K07020302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11149
RABL2A	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997409
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46317
BRD-K89366259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12196
Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.61441
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08652
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1234
GSE158834_10_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGBC11TKB	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-6.84876
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.237
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23907
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A1207	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30788
other organism part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202346
protein transport	GO Biological Process Annotations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8394-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranulocytosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
SNU-C2B	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.24126
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OPA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53631
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229096
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65123
KARPAS-620	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.8595
CAOV4	CCLE Cell Line Gene CNV Profiles	1.0	1.92618
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60783
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35002
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61796
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8074
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476011
fluorouracil_homo sapiens_gpl550_gds848	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.06845
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46834
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382244
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94006
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.767935
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49968
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60619
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27609
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9011
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNDP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149359_3_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01232
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58691
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5938
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999308
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5714
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.1774
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11302
SLR25	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16316
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142727
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866386
ATF3	ENCODE Transcription Factor Targets	1.0	null
OSBPL3	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SMAD2	Pathway Commons Protein-Protein Interactions	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14655
7569_RRS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504678
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34973
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42886
BRD-K97298761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60028
Myelofibrosis	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43818
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE4470_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79204
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03691
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0828
BRD-K65184008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54598
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41574232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33792
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04406
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92483
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214637
BB-62-MS83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218468
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24653
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
K562_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183871
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARHGAP8	Pathway Commons Protein-Protein Interactions	1.0	null
A549_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145818
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15628
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
MOSPD2	Pathway Commons Protein-Protein Interactions	1.0	null
MES-SA	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.4123
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38975
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319666
SH3GLB2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835174
NELFE	ENCODE Transcription Factor Targets	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835855
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87535
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARHGAP18	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04481
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4355
MCF7_Trametinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118118
HLA-B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865399
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIN3A_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JM1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.22482
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KARPAS-299	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIGLEC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00503584
Severe congenital neutropenia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2088
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208686
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888728
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.783679
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11066
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12166
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54637865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83536
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3474
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LYN	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K26836050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30921
PPP2R2D	Pathway Commons Protein-Protein Interactions	1.0	null
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948517
cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613167
ARC syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.849912
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
RB_Deficiency_GDS2757_644_mouse_Embryonic livers (day 12.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.16285
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.93235
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
Disease	Reactome Pathways 2024	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86968
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79456
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50719
CRCGN016_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10642
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30643
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376119
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51881
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180834
MCF7_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110616
GTEX-U3ZH-1126-SM-4DXUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18536
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9308
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1GDS1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synovial sarcoma_Synovial Membrane_GSE6461	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.5961
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
picotamide-1387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015826
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.60235
BRD-K41031262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05912
lateral part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22434
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174635
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07781
PKLR	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15328
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00513
Extracutaneous mastocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OLIG2	ChEA Transcription Factor Targets	1.0	null
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10908
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05114
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7677
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906725
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16553
MCF7_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191764
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54850621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0669
GSE205788_0_v_1_gfap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26826253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05365
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.284032
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7038
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995091
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904378
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28274
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
13_AARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.5549
WDR1	Pathway Commons Protein-Protein Interactions	1.0	null
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
Golgi membrane	GO Cellular Component Annotations 2025	1.0	null
GA-66-IX54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201404
BRD-K05586628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42887
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50472
PTK2	Pathway Commons Protein-Protein Interactions	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340722
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.336
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59269
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388535
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3347
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848599
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26371
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174635
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.336241
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289938
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46005
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050287
Plant vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.515
nucleus subceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02423
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014914
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15264
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0342954
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55432
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8552907__F4	PFOCR Pathway Figure Associations 2024	1.0	null
A204	BioGPS Cell Line Gene Expression Profiles	1.0	1.75528
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49741
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834553
UGDH	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954608
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.759609
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87670244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54149
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22534
ZEB1	ENCODE Transcription Factor Targets	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4055
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955376
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34119
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
A549_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131429
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20244
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905905
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12009
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.03976
PMP2	Hub Proteins Protein-Protein Interactions	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923417
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835855
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.879319
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79734831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15231
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.324
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20281
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956323
LNCAPCLONEFGC_PROSTATE	CCLE Cell Line Proteomics	1.0	2.06478
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PMC7468567__F4	PFOCR Pathway Figure Associations 2024	1.0	null
19061838-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03157
Thyroid Hormone Plasma Membrane Transport Defect	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNF8	Pathway Commons Protein-Protein Interactions	1.0	null
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
BRD-K03606830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18926
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00154
neurodevelopmental delay	HPO Gene-Disease Associations	1.0	null
Early infantile epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971584
mantle zone of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09195
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512171
GTF2B	ENCODE Transcription Factor Targets	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC61G	Pathway Commons Protein-Protein Interactions	1.0	null
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.06977
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGK1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25708
Familial myelofibrosis	CTD Gene-Disease Associations	1.0	2.88009
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of bone marrow cell morphology	HPO Gene-Disease Associations	1.0	null
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8385
MYBPC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00521788
Fatty Liver	CTD Gene-Disease Associations	1.0	1.57234
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029358
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Exodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.19767
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
abnormality of granulocytes	HPO Gene-Disease Associations	1.0	null
INPP4B	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Decitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138773
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31036
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EW-13	GDSC Cell Line Gene Expression Profiles	1.0	1.52986
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17193
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46639367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24595
Perturb_18496_KD_LINC00881_SRP362016	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.3378
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64889
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-760	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BLOC-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00059
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56284
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOS	CCLE Cell Line Gene CNV Profiles	1.0	1.50538
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13351
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158766
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42396
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12541
Severe congenital neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.88
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28869
Perturb_13701_KD_NKX21_SRP335544	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.80344
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1193	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
A549_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213224
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907554
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
PMC12486367-Supplementary_Data2.pdf-8-ZNF441_ZNF441	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.502
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4759
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08909
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Sodium Phenylbutyrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0256434
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.55
BRD-K25805580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22552
CRCGN014_HEPG2_3H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31122
endosomal	GeneRIF Biological Term Annotations	1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.591
SW1116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38095
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.841893
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.11011
CAKI2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14697
vesicle docking involved in exocytosis	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02139
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3GL2	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159938
BRD-K48860650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87463
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40786
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05375
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.48598
BRD-K77609086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42062
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01339
BRD-K91726436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11155
ERMES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25468
oxolinic acid-2266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04235
Organic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34601
Lung adenocarcinoma_LUAD_TCGA-05-4427-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278176
SNX13	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.262
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
8890_THOC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621182
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.69808
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Regorafenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151553
MTHFD1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11693
MCF7_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230555
RUFY1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15226
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.184
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576415
BRD-K03713632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68845
TAOK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6899
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z4-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAY-11-7085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21008
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3789
PMC11385326-joces-137-261952-TableS5.xlsx-AP2_possible_interactors-Gene_names_AP2_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50059
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21384
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
intermediate stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78045
HSPH1	Pathway Commons Protein-Protein Interactions	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213532
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Perturb_9159_KD_DHX9_SRP346212	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896388
SLR20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45342
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16245
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCIH1048	CCLE Cell Line Gene Expression Profiles	1.0	1.97257
endosometogolgi	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98064
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDHL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.05939
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
EBC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-5.99903
BRD-K82401173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89495
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ab_M_YW (RFWD3)	NURSA Protein Complexes	1.0	null
pancytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.642615
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	0.916015
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13557
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863473
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68341
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92844
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83752
Roxadustat_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0101336
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.779
CREB1-15753290-HEK293T-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87712055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02628
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29173
Proteinuria	CTD Gene-Disease Associations	1.0	1.13963
BRD-K33194123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15951
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11358
K562_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196489
USF1	ENCODE Transcription Factor Targets	1.0	null
PMC5806898-pbio.2004411.s003.xlsx-MR_plot_data-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.082
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00382
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03231
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00827
H3K79me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873978
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OTUB1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8018
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCK2	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PTPN6	Pathway Commons Protein-Protein Interactions	1.0	null
Syndactyly type 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
SIN3A	ENCODE Transcription Factor Targets	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A27422067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04499
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05386
SNX17	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40168
BRD-K27911943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1626
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887653
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21189
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0031
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20283
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
gout	GWASdb SNP-Disease Associations	1.0	1.15334
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF263	ENCODE Transcription Factor Targets	1.0	null
KRT18	Pathway Commons Protein-Protein Interactions	1.0	null
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.51213
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.902117
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25931
Sec1-like protein	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2418
K562_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183068
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863287
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0306
RBPJ	ChEA Transcription Factor Targets	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94651
BRD-K35978846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02968
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26231789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33586
PMC4474670__F3	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40068
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2309
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263992
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.765843
KAT2A	ENCODE Transcription Factor Targets	1.0	null
MCF7_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140309
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0231534
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FNBP1L	Pathway Commons Protein-Protein Interactions	1.0	null
PGM2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.869067
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31743
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908937
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974472
APPL1	Pathway Commons Protein-Protein Interactions	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HT29	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.91771
K562_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168853
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834887
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOC8	Pathway Commons Protein-Protein Interactions	1.0	null
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55072
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02563
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1851
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
Cellular bud neck contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16869
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28403
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anemia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K43468685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31153
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13779
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19538
LN443	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42493
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Columella	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66848
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34016
Poikiloderma with neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.731
Promyelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
Basolateral cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
haptoglobin-hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302478
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11367
RRAS	Pathway Commons Protein-Protein Interactions	1.0	null
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30752
BRD-K73025852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1759
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328148
TIMM44	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00194
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABAT	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994703
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D4	Pathway Commons Protein-Protein Interactions	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
NACA	Pathway Commons Protein-Protein Interactions	1.0	null
BZW1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02336
EDD_DEPLETION_GDS2445_116_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26744
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_6413_KO_TP53_SRP274402	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.58071
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	0.899099
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2521
myelofibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.15666
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21446
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36481
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NME1	Pathway Commons Protein-Protein Interactions	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255451
mefenamic acid-5534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITPNA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35515
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.01841
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041908
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833584
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	1.40855
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2288
abnormality of the lymphatic system	HPO Gene-Disease Associations	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRTC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444273
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A47963183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21679
MCF7_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169206
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154991
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059128
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZN-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCUR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00362595
K562_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142899
16288205-GeneTable3	GeneSigDB Published Gene Signatures	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6385
blood platelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23459
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848705
endosometorecycling	GeneRIF Biological Term Annotations	1.0	null
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	1.46585
MCF7_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151536
EPI-2603-1 (PTTG1)	NURSA Protein Complexes	1.0	null
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06628
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053623
SNX6	Pathway Commons Protein-Protein Interactions	1.0	null
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.382
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318206
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2938
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K21955645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32047
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852651
PCTP	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464221
MCF7_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208901
BRD-K63668467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04653
RRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
HC-86-IA49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398673
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_3586_KD_KHSRP_SRP250831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.70853
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14851
Rab-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
pilocarpine-2438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.5186
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.606487
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.702
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.83843
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52463
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3073
rabenosyn5	GeneRIF Biological Term Annotations	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0047
GDI2	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52043
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13535
MCF7_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204726
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878339
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4736-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504264
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41275
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D9-01B-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31531
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0284
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847602
Activin responsive factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.337
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3064-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967935
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00980118
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17322
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01716
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903411
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11385326-joces-137-261952-TableS5.xlsx-AP1_possible_interactors-Gene_names_AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03906
Reticular dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
EXPH5	Pathway Commons Protein-Protein Interactions	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10484
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02657
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91828
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8121
Pancytopenia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12547
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13288
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45726
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00798
SCAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06037
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19323
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.50172
YIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
MALL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528298
Severe congenital neutropenia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.707023
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01761
hsa-miR-4437	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
MCF7_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127882
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841582
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39932
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRX-20693478-ADULT-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20447569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12105
RALA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3611
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37887
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.118297
BRD-A69786436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82342
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74668
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0388126
BRD-K00938872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26453
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
VAPB	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3603
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231028
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4507	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
golgi membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827274
LAMTOR3	Pathway Commons Protein-Protein Interactions	1.0	null
A549_BMS-911543_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148002
GM2345	BioGPS Cell Line Gene Expression Profiles	1.0	0.829223
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918643
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883209
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76534
Lung Injury_Lung Tissue_GSE1541	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.77219
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938179
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27793
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7017
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11084
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23714
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960783
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5495
protein localization	GO Biological Process Annotations 2025	1.0	null
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX27	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13347
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17757
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36099
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89932
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30467
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.83953
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13461720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1465
MCF7_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136702
Anterior cingulate area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14622
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.52
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904548
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13732
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172175
CCDC121	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465321
E2F4	ChEA Transcription Factor Targets	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63022
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
G402	CCLE Cell Line Gene Expression Profiles	1.0	2.75198
ESCRT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
Exocrine pancreatic insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Lung adenocarcinoma_LUAD_TCGA-MP-A4T8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227289
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40001470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50344
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital Neutropenia	DisGeNET Gene-Disease Associations	1.0	null
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K35119180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40285
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10644
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3762
hsa-miR-4674	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1506
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195338
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35916
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19281
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01232
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03625
BCPAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.989
golgi apparatus part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HSPE1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845452
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835274
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0965
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76397
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56427898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11975
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80053
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2288
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	0.927595
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73819
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT55	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77872
TCF7	ChEA Transcription Factor Targets	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93419
snare complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.538649
MCF7_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168294
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6205
K562_Thiotepa_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172864
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385896
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86877
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959851
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BLOC1S1	Pathway Commons Protein-Protein Interactions	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09450441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03329
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281994
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE97870,GSE97871_1_v_0_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89784
TNK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46388
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8464
ADPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77815
hsa-miR-16-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0958
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
TTI1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal leukocyte count	HPO Gene-Disease Associations	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9121
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.0013
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ARH77	DepMap CRISPR Gene Dependency	1.0	2.06785
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAOK3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K09295309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33426
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40982
agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.866321
SEL1L	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39086
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.259
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87848
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32988
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.946691
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12118
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate gland	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.956477
MCF7_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160258
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060351
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUP	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN015_MCF10A_48H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33367
JM1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	10.4693
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11218
A549_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138613
K562_ABT-737_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168641
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218537
BRD-K39664334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95104
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
IDH2	Pathway Commons Protein-Protein Interactions	1.0	null
Cardiomyopathy, Dilated_Myocardial tissue_GSE3586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68167
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97472167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03462
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4736
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.827563
BRD-K76175734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06987
C-75-6394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51968
A549_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013441
K562_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214213
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HKGZCC	DepMap CRISPR Gene Dependency	1.0	2.04241
ATP6V0C	Pathway Commons Protein-Protein Interactions	1.0	null
RINT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907364
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3388
Necrosis	CTD Gene-Disease Associations	1.0	1.49381
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00973
CUX1	ChEA Transcription Factor Targets	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06534
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950545
NSDHL	Pathway Commons Protein-Protein Interactions	1.0	null
TALL-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.16401
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7930_KD_ZCCHC8/ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.5538
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
AC-36-SY22_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279223
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23704
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
BRD-K75094875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20977
TTC19	Pathway Commons Protein-Protein Interactions	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9908
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07084
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Severe congenital neutropenia	ClinVar Gene-Phenotype Associations 2025	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55605
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873514
MTOR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27949240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9735
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17077
BRD-A75607876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19539
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K20560768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12379
9065_DMAC1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.791793
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.07579
HMGN3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33979719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02604
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06524
HYOU1	Pathway Commons Protein-Protein Interactions	1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.25985
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930795
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942056
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323672
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.939863
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WLS	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018164
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
RABEP1	Pathway Commons Protein-Protein Interactions	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178777
ARFGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31184
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88817
SCABER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16818684-Table2a	GeneSigDB Published Gene Signatures	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8238
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01736
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.922708
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84012
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910352
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89113
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357602
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38152
ABR	Pathway Commons Protein-Protein Interactions	1.0	null
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460487
KIAA1033	Pathway Commons Protein-Protein Interactions	1.0	null
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832419
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71959
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5106
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.67112
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291954
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.46186
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
9592_UNC45A_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.523462
BRD-K32723442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56012
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53517
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385251
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00233
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922724
SARS-CoV MA15_Day4-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83923
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18432
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.226
MCF7_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115531
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846951
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01302
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.37852
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12283
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95519
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20698
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14995
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385066
BRD-K03810133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04579
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0724
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
STX3	Pathway Commons Protein-Protein Interactions	1.0	null
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06787
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340623
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43099
megakaryoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139391
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07802
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22245
SLC30A9	Pathway Commons Protein-Protein Interactions	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
hsa-miR-1286	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.226
HIP1	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54989
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85435
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0258911
FOXA1	ENCODE Transcription Factor Targets	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VRK1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Severe congenital neutropenia 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
layer 5 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05371
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60184
CHMP6	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3101
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88087
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15416
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_BMS-911543_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014773
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99717
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17015
CAL-29	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.81502
BRD-K33986892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06989
GSE164884_2_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296405
PCYOX1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65284
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2L3	Pathway Commons Protein-Protein Interactions	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7816
A549_Ellagic acid_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157127
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17146
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02628
GTEX-UJHI-0926-SM-4IHKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03432
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0686
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56428
BRD-K82839033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31422
MCF7_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0314227
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5993
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
SHD	Pathway Commons Protein-Protein Interactions	1.0	null
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.85702
ETFA	Pathway Commons Protein-Protein Interactions	1.0	null
OPM2	CCLE Cell Line Gene CNV Profiles	1.0	1.44201
KCL22	DepMap CRISPR Gene Dependency	1.0	2.02947
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59559
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6156
superficial stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32764
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C8-06A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27331
A549_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151281
KDM4A	ENCODE Transcription Factor Targets	1.0	null
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00354
SFT2D2	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Tranylcypromine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153195
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC7468567__F4	PFOCR Pathway Figure Associations 2023	1.0	null
KNTC1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11880379-41467_2025_57480_MOESM3_ESM.xlsx-SOX9_RIME_Limma-Gene_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G415	DepMap CRISPR Gene Dependency	1.0	2.03984
A549_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137363
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS37B	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18926
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68658
superficial stratum of FCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.091
Perturb_7928_KD_EXOSC3_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.80827
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46388
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DU-145	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01232
SNAPIN	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1857
coralyne-6317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.21498
CEBPD	ENCODE Transcription Factor Targets	1.0	null
H9	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.77601
AA-98-HX85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222136
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Membrane Trafficking	Reactome Pathways 2024	1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17772
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.897278
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19019
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32551
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858732
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB1B	Pathway Commons Protein-Protein Interactions	1.0	null
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182153
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04473
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12096
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977647
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4951_MED28_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.643022
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00265
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331092
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
DOPEY2	Pathway Commons Protein-Protein Interactions	1.0	null
PTPRM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541306
4-P-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22404
TBC1D1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K69678391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23065
BF-02-AC95_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466967
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
TSC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89194
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00836
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19378
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143388
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19901
endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.439333
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0116
Microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
MCF7_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156476
MCF7_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156676
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMF1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34079
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00247
CTB-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74902
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00901
PMC9164468-13073_2022_1056_MOESM1_ESM.xlsx-S7_ARNT_alteration-Gene_ID_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09803
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6988
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4597
trans-golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.693393
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03987
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.032
Bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.977
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
BRD-K92929998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09432
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6732
lifethreatening	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57427
BRD-K99034771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5899
EXOC6	Pathway Commons Protein-Protein Interactions	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2963
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subcuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868696
EZH2	ENCODE Transcription Factor Targets	1.0	null
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831624
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915171
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01619
BRD-K35711197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06048
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARHGEF10L	Pathway Commons Protein-Protein Interactions	1.0	null
STAT5A	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25817
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC11437185-41467_2024_50986_MOESM4_ESM.xlsx-MECOM-IP-MS-Gene_names_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919058
NFIC	ENCODE Transcription Factor Targets	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09405
KDM1A	ENCODE Transcription Factor Targets	1.0	null
endosomal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K77445233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26987
HDAC6	ENCODE Transcription Factor Targets	1.0	null
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890257
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40653
ERBB2IP	Pathway Commons Protein-Protein Interactions	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14809
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
early	GeneRIF Biological Term Annotations	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61186
WHSC1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7614
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Protein Deficiency	DisGeNET Gene-Disease Associations	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97644
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970999
Shwachman-Diamond syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
KRT10	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.662972
Chediak-Higashi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19731191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26005
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47966145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81536
MCF7_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197927
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70026
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
UNC93B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28939
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.652
GBF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35129
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.948284
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19248
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158793
BRD-K94936556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3352
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_14_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87274
TNPO2	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PSAP	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TPI1	Pathway Commons Protein-Protein Interactions	1.0	null
neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584022
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ANP32B	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872173
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876474
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hemostasis	GO Biological Process Annotations 2015	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42471
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042983
intracellular transport	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
MEF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20779
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZE-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIP1R	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K32021110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53058
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909036
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173818
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60342
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Casparian strip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46305
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04574
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
RAP2B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28738
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.386
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4829
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08809
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949194
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885515
K562_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183075
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89494
who	GeneRIF Biological Term Annotations	1.0	null
ZNFX1	Pathway Commons Protein-Protein Interactions	1.0	null
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84774
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
CDHR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611351
Ric1-Rgp1 guanyl-nucleotide exchange factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48563
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15393
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989095
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28344
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3987
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-34-HOXA9_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754372
PSMA5	Pathway Commons Protein-Protein Interactions	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492679
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59051
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10196
BHY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3415
K562_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160392
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA9	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203837
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypodermal seam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
ARHGAP17	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159427
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRTP1	Pathway Commons Protein-Protein Interactions	1.0	null
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348706
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26937
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.66115
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1290	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00947
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04263
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
OCI-M1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.43734
ZNF827	Pathway Commons Protein-Protein Interactions	1.0	null
LNZ308	CCLE Cell Line Gene CNV Profiles	1.0	2.07158
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15393_KD_CHKA_SRP050331	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.73303
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPI	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Cerdulatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0287564
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162832
RALB	Pathway Commons Protein-Protein Interactions	1.0	null
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
Cardiac Failure_Myocardial tissue_GSE1988	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.56878
KA-71-CQ35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240306
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Phenytoin (sodium)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0257902
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35202
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88959
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389931
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864459
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pseudostem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
A549_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016043
Phragmoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25439
cefaclor-2483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100428_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00737
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18908
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18136
adult stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.44094
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36845
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.43874
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36244
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04834
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152518
GOSR1	Pathway Commons Protein-Protein Interactions	1.0	null
Pellicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35741
PLEK2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K42799692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27279
RBFOX2_02_101	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58896
Ethmoid sinusitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5715
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAGLB	Pathway Commons Protein-Protein Interactions	1.0	null
PK59	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91873
MCF7_Iniparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190026
DHX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39726
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57962
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988821
nialamide-3790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81198
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21166
endosome membrane	GO Cellular Component Annotations 2023	1.0	null
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0235304
ARHGEF1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165711
MCF7_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171181
NF1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN_KO_GDS4205_294_mouse_B lymphoid cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77359
CAMA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
CRCGN017_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01016
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32998
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DSP	Pathway Commons Protein-Protein Interactions	1.0	null
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951791
Encysting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1478
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.24475
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03003
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
ARF6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26559753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11549
PMC4519954__F13	PFOCR Pathway Figure Associations 2023	1.0	null
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986589
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81844
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
CDC42BPG	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88906
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45172
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27468
hsa-miR-4417	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Vesicle-mediated transport	Reactome Pathways 2024	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043193
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04437
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38336
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.39939
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5993681-mmc4.xlsx-Tabelle1-Metacore_analysis_of_SRF_binding_targets_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126132
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03628
Splenomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40599
K562_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.033124
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
K562_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188312
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12358
PMC5638334__F10	PFOCR Pathway Figure Associations 2023	1.0	null
Late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.152
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156668
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
VPS72	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570911
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186397
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24975
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1752
CAL-51 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17173
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909315
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
RAB35	Pathway Commons Protein-Protein Interactions	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.890761
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
Rucaparib (phosphate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0202098
LDHA	Pathway Commons Protein-Protein Interactions	1.0	null
RAB10	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907086
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
SK-N-DZ	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.43222
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27057
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857386
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0596
2633_EN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.578816
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857265
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04394
hsa-miR-1258	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K25877330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25785
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13491
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16969
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42424
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LS1034	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05255
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240969
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1643
IOMMLEE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5277
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
MED14	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61152
K562_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117385
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16479784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35259
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
decreased body weight	HPO Gene-Disease Associations	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944234
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49117
KMS28BM	CCLE Cell Line Gene CNV Profiles	1.0	1.48285
BRD-K10189430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19815
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMC1	Pathway Commons Protein-Protein Interactions	1.0	null
thiamazole-3898	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW626	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20868
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARAF	Pathway Commons Protein-Protein Interactions	1.0	null
Wiskott-Aldrich syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
RS11846	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.897683
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42423
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35534
Ring stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970023
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043026
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60084
Charcot-Marie-Tooth disease type 4K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939083
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12547
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.18527
YBX3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
K562_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168253
BRD-K82126187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02099
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1974
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33504
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.65325
Endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RPL18	Pathway Commons Protein-Protein Interactions	1.0	null
DiFi	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.21243
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTPBP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K40260328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58291
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2955
BRD-K08730634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95651
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5195
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.706
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.670518
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.569248
K562_PCI-34051_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019133
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0229903
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825932
FIG4	Pathway Commons Protein-Protein Interactions	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204191
A549_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150086
K562_PF-573228_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174021
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13677
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.983608
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.269043
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A69M-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56008
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23114
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17839
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41745
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.889668
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16773
ERGIC1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25332
CLASP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86143816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14246
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826624
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72888
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72591
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-E2F1_UP_V1_DN-Gene_name_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5501
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
their	GeneRIF Biological Term Annotations	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5384
FLI1	ChEA Transcription Factor Targets	1.0	null
WHIM syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Factors involved in megakaryocyte development and platelet production	Reactome Pathways 2014	1.0	null
P2RY8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526384
MCF7_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140783
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869435
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.532
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62342
Intra-Golgi and retrograde Golgi-to-ER traffic	Reactome Pathways 2024	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AZD1480_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120828
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55932
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNAQ	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
8505C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32644
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85887
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
K562_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184934
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77249
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4419
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910209
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.413
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221823
CRCGN015_HEPG2_48H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60924
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1734	CCLE Cell Line Gene Expression Profiles	1.0	1.48248
MOB1B	Pathway Commons Protein-Protein Interactions	1.0	null
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03167
OSBPL8	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80198069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31986
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863856
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430695
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1887
BRD-K41451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40744
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
ECSIT	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8391
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Autosomal dominant severe congenital neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
CDK11A	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKP1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13436
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MHCC97-H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69937
ACSF2	Pathway Commons Protein-Protein Interactions	1.0	null
FIS1	Pathway Commons Protein-Protein Interactions	1.0	null
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05246
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857265
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
FERMT1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1082
K562_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152419
retromer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.375818
PPARD	ChEA Transcription Factor Targets	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.581
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0166
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23385
K562_Bosutinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169475
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.592
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.252
Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDH2	Pathway Commons Protein-Protein Interactions	1.0	null
CAOV-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31003
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6846
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72588970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14395
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914867
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.592
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78964
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02603
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y6-01A-21R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6139
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00951
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Micropyle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50598
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.41
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44506
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.547459
YKT6	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6683
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994812
VCL	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08300592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1107
BRD-K40838215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25038
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920906
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.67872
BRD-K05657319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40753
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69462
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
butoconazole-5388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DYNLRB1	Pathway Commons Protein-Protein Interactions	1.0	null
HSPB1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UACC-812	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.47083
BRD-K41141507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18187
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37203
Gingivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
Optic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5287
Somatomotor areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24922
golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.277406
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10639
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.029571
BRD-K21986392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67129
membrane part	GO Cellular Component Annotations 2015	1.0	null
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894057
MCF7_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163113
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11589
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204437
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21511
underlies	GeneRIF Biological Term Annotations	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65169
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
COLO-792	GDSC Cell Line Gene Expression Profiles	-1.0	-2.83689
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.866408
GOT1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.06083
GALC	Pathway Commons Protein-Protein Interactions	1.0	null
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	1.49826
KRT8	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_7959_KD_ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.2583
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.57596
SW962	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.12045
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09911
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58312
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
A549_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166135
USO1	Pathway Commons Protein-Protein Interactions	1.0	null
consanguineous	GeneRIF Biological Term Annotations	1.0	null
CBC632 (AKAP13)	NURSA Protein Complexes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75764
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1329
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MLL_fusion_common_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08767
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.72227
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76262
ARRDC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694948
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71735
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14688
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.241
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03579
A549_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135997
CLCN7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36426
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39369
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96772
SMARCC2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21242
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.136372
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.604
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_280_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876825
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59526
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862466
CRCGN010_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10127
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55169051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20443
17970077-Table6	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64459
MCF7_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0108246
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.841051
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PFKL	Pathway Commons Protein-Protein Interactions	1.0	null
embryonic lethality between implantation and placentation, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SAOS2	BioGPS Cell Line Gene Expression Profiles	1.0	0.964561
NCI-H1876	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
STX18	Pathway Commons Protein-Protein Interactions	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09569
POU3F2	ChEA Transcription Factor Targets	1.0	null
Ssh1 translocon complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
Raji	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77219
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0349
HOOK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28268
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169636
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859784
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.31525
Rvs161p-Rvs167p complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50897
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914995
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17022
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15229
Transforming growth factor beta ligand-receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11116
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8125
NCIH1876	CCLE Cell Line Gene Expression Profiles	1.0	1.9436
EFM-19	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.39059
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201892
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253728
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARHGEF26	Pathway Commons Protein-Protein Interactions	1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ghosal hematodiaphyseal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30421
Sec1-like, domain 2	InterPro Predicted Protein Domain Annotations	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	Pathway Commons Protein-Protein Interactions	1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205628
CSNK1D	Pathway Commons Protein-Protein Interactions	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055232
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25641
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898984
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.660759
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01306
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.31956
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328898
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
Hydathode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542806
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18874
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827995
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90681
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
BLOC-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
BRD-K16789950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18466
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
SF126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3458
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57705
MCF7_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011911
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61215
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.908146
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49614
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
VPS26A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50859531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78155
BRD-K29502299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23225
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89113
MCF7_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195916
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33242
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9652_USP36_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.26029
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1482
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HK2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84573
A549_Bisindolylmaleimide IX_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134953
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
TSG101	Pathway Commons Protein-Protein Interactions	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53112
MYC_Activation - 24 hours_GDS2025_726_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933895
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59299
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.0698
TAP2	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the liver	HPO Gene-Disease Associations	1.0	null
BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_HA1E_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871773
HCC1187	CCLE Cell Line Gene Expression Profiles	1.0	1.65061
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02988
Inflammation	CTD Gene-Disease Associations	1.0	1.45168
K562_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172137
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70I-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0047
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36859
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32807
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35925
GSE110268_0_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.16996
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00046
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19487
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.908198
MCF7_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134307
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838698
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057076
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96356
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886185
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.028756
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12756
BRD-A95970093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32429
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965988
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08472
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01777
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50861
Normoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337365
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834553
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63086103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40365
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
SYNJ2BP	Pathway Commons Protein-Protein Interactions	1.0	null
UF-14-LK87_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308807
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5845
intracellular protein transport	GO Biological Process Annotations 2025	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11365
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38986
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
visceromegaly	HPO Gene-Disease Associations	1.0	null
A549_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155363
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0181
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.555353
MCF7_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152853
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137137_1_v_0_rcor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3815
BRD-K14987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37055
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.6284
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07379
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41352
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.865961
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MCF7_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214835
nexus	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56508
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	1.44617
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42263
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015336
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6338
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATIC	Pathway Commons Protein-Protein Interactions	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.827712
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891605
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233088
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
EARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.449
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
abnormality of cell physiology	HPO Gene-Disease Associations	1.0	null
Multivesicular body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.784
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08355
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS28	Pathway Commons Protein-Protein Interactions	1.0	null
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68379391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36128
BRD-K86065375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23365
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29445
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.841907
CHP1	Pathway Commons Protein-Protein Interactions	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36673
CCL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633374
Glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862295
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2023	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65873
BRD-K34456337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07895
BRD-K83877780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52126
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19768
Planktonic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1632
IC-80-CT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211632
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31678817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2243
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.962697
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02108
TBC1D9B	Pathway Commons Protein-Protein Interactions	1.0	null
reticular formation of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92566
Nimesulide_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0163306
MCF7_M344_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198629
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLOC1S2	Pathway Commons Protein-Protein Interactions	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16422
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13428
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915738
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8599_SUPT6H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.619521
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-1100-3798	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76215709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0587
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A36774080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29381
DTD1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13959
Perturb_11423_KD_AR_SRP324259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02683
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2701
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940392
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33956641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4391
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98999
BRD-K38692266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56883
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal neutrophil cell number	HPO Gene-Disease Associations	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12864860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10384
Factors involved in megakaryocyte development and platelet production	Reactome Pathways 2024	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26478
Leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848305
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00493
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.2032
CRCGN013_HEPG2_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17648
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0134
BRD-K67183010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03907
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96353
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08128
MCF7_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158153
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10295
E2F1	ChEA Transcription Factor Targets	1.0	null
Perturb_14746_OE_MEOX2_SRP330486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.67171
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02877
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1417	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62172
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81316
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314245
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54094
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-3 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064629
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.03667
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PP-0726-SM-3NM9S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995171
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99746
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260555
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48217
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8139-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058257
myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.662784
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0226
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25666
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1E1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829349
RELA	ENCODE Transcription Factor Targets	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201574
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51255
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89113
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003226
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89932
RIC8A	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68424387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28388
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Multivesicular body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29982
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03345
Periciliary membrane compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
MB-32-LQ97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202135
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYNU	Pathway Commons Protein-Protein Interactions	1.0	null
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
HMC18	DepMap CRISPR Gene Dependency	1.0	2.01113
BRD-K06729289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21635
DC-51-WE27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327749
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92978
Pancytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65488906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58393
hsa-miR-613	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
SNX7	Pathway Commons Protein-Protein Interactions	1.0	null
Coated membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.832
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLPH3	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K25709301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40665
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73894
SOX2-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17238
MCF7_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151292
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53334
BV173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.617
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37315860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11518
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29211
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
EKVX	BioGPS Cell Line Gene Expression Profiles	1.0	1.81898
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2902
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Severe congenital neutropenia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871139
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1565
DYNLL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00398869
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79267333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43854
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03205
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8997
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0067
MCF7_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171658
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1126
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468219
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03078
K562_TG101209_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195448
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AP1S2	ChEA Transcription Factor Targets	1.0	null
K562_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181762
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hs-766T	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.34189
Sarcoma_SARC_TCGA-DX-A240-01A-32R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20398
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3874167-supp_gkt849_Supplement_Table_S1.xls-DREAM_-_TSS_clearly_affiliated-Gene_name_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14069
U-698-M	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.47518
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.603588
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320908
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A	Pathway Commons Protein-Protein Interactions	1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV-2 modulates autophagy	Reactome Pathways 2024	1.0	null
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1744
TRAPPI protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34109
BB-20-UU03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308219
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
16455954-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K10761381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69945
APEX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58529
ERP27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584857
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOPC	Pathway Commons Protein-Protein Interactions	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.11639
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02655
corvet complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.98927
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1623	CCLE Cell Line Gene Expression Profiles	1.0	1.92803
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9475
SGK3	Pathway Commons Protein-Protein Interactions	1.0	null
TRIM28_knockout_303_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.51442
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21099
YWHAB	Hub Proteins Protein-Protein Interactions	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920111
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.2191
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	2.09843
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956275
MCF7_Bisindolylmaleimide IX_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191728
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.21665
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907027
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein transport	GO Biological Process Annotations 2025	1.0	null
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91511
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11844860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01154
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0704
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A44438286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34534
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Leukocyte disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02918
abomasum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
7476_RPL6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520305
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.835547
WIL2-NS	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.13873
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24962
SKCO1_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.15687
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06488
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4854
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02118124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46834
PL4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903377
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060748
GAPDH	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EEA1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3131
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8992
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2041
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:I18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00695
plastid-encoded plastid RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
macromolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07348
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_3_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_PHA-680632_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178901
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266957
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35982
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51565
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00906874
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65646
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31194
KON	DepMap CRISPR Gene Dependency	1.0	2.03312
OCI-AML2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.26221
PDCD4	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60460300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08601
CDC42SE2	Pathway Commons Protein-Protein Interactions	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62164
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869172
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49490091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01205
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833276
MCF7_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118887
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850491
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.71709
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K25917968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39426
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
GOLGA7	Pathway Commons Protein-Protein Interactions	1.0	null
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453192
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84988
TXN	Pathway Commons Protein-Protein Interactions	1.0	null
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.587
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06595
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.807
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488796
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062135
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17978
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARL8B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A56345662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1784
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942993
LSG1	Pathway Commons Protein-Protein Interactions	1.0	null
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MCF7_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177935
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02388
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17256
STX5	Pathway Commons Protein-Protein Interactions	1.0	null
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.50132
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35081
RFX5	ENCODE Transcription Factor Targets	1.0	null
Candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
MCF7_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0232143
Gut granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
KOPN8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35991
Brain Lower Grade Glioma_LGG_TCGA-FG-A87N-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03461
BRD-K46699670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03943
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051577
PKM	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K02078984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4386
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32022
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
BRD-K34110797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10527
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16207
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PITPNM1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050366
early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.862609
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72139
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859275
MCF7_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0276219
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07294
GM2A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3967
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09762
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
K562_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154185
A549_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177246
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3638
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06908
BE-16-UV45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248008
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.703553
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96142
MCF7_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215319
frontal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09195
BRD-K78217087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81736
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238246
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDIA3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KBTBD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637612
EP300	ENCODE Transcription Factor Targets	1.0	null
MEF2A	ENCODE Transcription Factor Targets	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
Primary Myelofibrosis	DisGeNET Gene-Disease Associations	1.0	null
anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067463
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04602
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
rDNA protrusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3381
RAP2C	Pathway Commons Protein-Protein Interactions	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53719
TAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20539
4208_ISG20L2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510716
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928629
Perturb_12062_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
due	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:A11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5824
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.883435
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5034
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.216
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TJP2	Pathway Commons Protein-Protein Interactions	1.0	null
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.724804
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31602464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29573
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0228
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.76076
COLO-824	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
abnormality of neutrophils	HPO Gene-Disease Associations	1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
HEBP2	Pathway Commons Protein-Protein Interactions	1.0	null
SACM1L	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
norcyclobenzaprine-2469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPC25	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.097
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01347
C6orf211	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143901
MCF7_ABT-737_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164362
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
STX16	Pathway Commons Protein-Protein Interactions	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25423
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1717
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667411
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31619
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173840_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92876
Viral Infection Pathways	Reactome Pathways 2024	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883528
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
EF-80-OD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.435031
BRD-K39179354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47696
K562_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021878
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54197
PMC3500769-srep00875-s3.xls-GATA3-Time_24_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GPR157	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473265
MCF7_S-Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194104
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48051
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7022
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14723
BRD-K37165790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05543
Anethole trithione_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0233232
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384572
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899294
A549_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194089
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853534
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979342
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.75748
MVB12A	Pathway Commons Protein-Protein Interactions	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACAD9	Pathway Commons Protein-Protein Interactions	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17488
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07851
ELK4	ENCODE Transcription Factor Targets	1.0	null
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03887
CLIC1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	1.00022
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pluripotent stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73107
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2004
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51152
CRCGN011_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53395
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70455
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16258
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859983
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35933
Neutropenia	DisGeNET Gene-Disease Associations	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16065
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168245
BRD-K83127279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46274
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	2.00398
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43803
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
ANKFY1	Pathway Commons Protein-Protein Interactions	1.0	null
OXSR1	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1092
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
BRD-K64902833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43554
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital neutropenia-myelofibrosis-nephromegaly syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11637
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56505
PL21	CCLE Cell Line Gene Expression Profiles	-1.0	-3.99892
along	GeneRIF Biological Term Annotations	1.0	null
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36069
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5577
Hypertension	CTD Gene-Disease Associations	1.0	1.19704
SHMT2	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017207
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214644
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29348
PPIG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00448593
TAF7	ENCODE Transcription Factor Targets	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06423
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08298
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10547
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immunodeficiency	GeneRIF Biological Term Annotations	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30615964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85231
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
AP1S1	Pathway Commons Protein-Protein Interactions	1.0	null
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
hsa-miR-206	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76505
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197289
Posaconazole_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0212176
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7877
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12923
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A704	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20222
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03596
RIGI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586181
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-32-EY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281104
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03257
HT	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.56331
K562_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017931
VPS52	Pathway Commons Protein-Protein Interactions	1.0	null
CDH6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00428385
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829938
BRD-K96417480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20609
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47391428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04034
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06395
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246305
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.08231
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03577
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
11142_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.632689
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64393896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77796
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848248
Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29439
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FFAR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055901
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962665
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09289
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.906607
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2633
OVISE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72607
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.05573
AA-68-OJ16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228648
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911999
LAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39062
BRD-K90956468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41392
Peripheral blood stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66445
BRD-K71605668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12191
Chief cell adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vacuolar HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
AMIGO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0048111
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
PRDX2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_124_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	0.836371
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15432_KD_CSN5_SRP316687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.78236
CRCGN012_HEPG2_24H:F15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14012
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05723
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	2.15519
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.739085
K562_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016129
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.520631
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280364
Lysosomal HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.648
FLI1	ENCODE Transcription Factor Targets	1.0	null
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02129
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07914
A549_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140984
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemostasis	Reactome Pathways 2024	1.0	null
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96617
K562_TMP195_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230323
MEF2A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.56015
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
omeprazole-2467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-34a-5p	MiRTarBase microRNA Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukopenia	HPO Gene-Disease Associations	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.903411
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Geleophysic dysplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.74103
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015045
CD-16-KY17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518355
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68391
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2393
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53271
GBA	Pathway Commons Protein-Protein Interactions	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17006
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27117
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10405
BRD-K12325488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74999
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68134791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16449
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81125
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842829
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.50844
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09212
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08821
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00084
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28259
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.842422
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3372
golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16542
localization	GO Biological Process Annotations 2015	1.0	null
endosomal part	GO Cellular Component Annotations 2015	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12166
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55958
tolazoline-4844	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K94833531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4483
IDH1	Pathway Commons Protein-Protein Interactions	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42017
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9492833__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06648
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60734
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32414
HTC-C3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60738
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.781619
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.64024
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.30138
Perturb_10434_KO_PPFIA1_SRP127326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.87054
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4673
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531519
Perturb_14656_KD_LINC00673_SRP102315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.41514
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal platelet count	HPO Gene-Disease Associations	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.1006
MCF7_BMS-911543_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01533
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	0.844507
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05651
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029389
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836847
A549_TGX-221_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164574
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79456
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.54019
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1048	GDSC Cell Line Gene Expression Profiles	1.0	1.76879
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17724
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.235
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31531
ESCRT I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.355
t47d	HPA Cell Line Gene Expression Profiles	1.0	1.22477
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874813
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09412
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.264785
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21837
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
ERGIC2	Pathway Commons Protein-Protein Interactions	1.0	null
7968_SLC16A5_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.19766
9804_WDR12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.664212
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12504
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66257
MCF7_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156928
MAPKAPK2	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
failure to thrive	HPO Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFA13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061466
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00921539
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941809
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.835369
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8915
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1692
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08355
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10713
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5231
TUBGCP2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224334
BD-48-ZT65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293556
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58598
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46134
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.943635
TEN	DepMap CRISPR Gene Dependency	1.0	2.01287
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49129
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26964
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
Cytoskeletal dynamics and intracellular transport	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6279
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AP3M1	Pathway Commons Protein-Protein Interactions	1.0	null
USPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52416
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-645	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K61711624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03603
15735721-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16396
APBA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496419
BRD-A05828965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87106
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03924
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A76904477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44734
STAT6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K21588993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.254
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6571
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60528
BRD-K76015448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43927
MAPK13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.869814
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.13772
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891397
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2228
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01807
GSE112860_9_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25475
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92195
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
SNU899	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128044
PDIA4	Pathway Commons Protein-Protein Interactions	1.0	null
HB1119	DepMap CRISPR Gene Dependency	1.0	2.04691
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88349
SLC22A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530733
Broad depression or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0301
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43002
Golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32659
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CS	Pathway Commons Protein-Protein Interactions	1.0	null
IDUA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643337
TKT	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144308
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastric mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3049
Brain Diseases	CTD Gene-Disease Associations	1.0	1.06225
Myelofibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
BRD-K76508844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24556
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy_Thymic epithelial cell_GSE85	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.84966
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208356
Glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42084
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04415
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00586
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_766_mouse_Skin - 0 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.68411
MCF7_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196701
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61068
Saul-Wilson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59829
HT-144	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853671
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20368
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059879
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IE-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Barasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137147
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16246
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_upregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
HAUS3	Pathway Commons Protein-Protein Interactions	1.0	null
prilocaine-4284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.943
A549_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155152
WASH2P	Pathway Commons Protein-Protein Interactions	1.0	null
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03461
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42507
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905091
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO1	CCLE Cell Line Gene CNV Profiles	1.0	1.41873
ZNF217	ENCODE Transcription Factor Targets	1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38477
3-methylglutaconic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153121
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63203
GTEX-XAJ8-0326-SM-47JYI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981807
Leukopenia	DisGeNET Gene-Disease Associations	1.0	null
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855282
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42537
K562_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148085
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58265
K562_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156956
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30932
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
neutropenia	HPO Gene-Disease Associations	1.0	null
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68846
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Raltitrexed_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017753
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03535
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060109
BRD-A88461048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0543
Mitotic actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
BRD-K66541472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41405
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00664
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infection By Cryptococcus Neoformans	DisGeNET Gene-Disease Associations	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89415
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855562
microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
blood coagulation	GO Biological Process Annotations 2015	1.0	null
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pure red-cell aplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1437	CCLE Cell Line Gene CNV Profiles	1.0	2.31036
GSE254526,GSE254528_0_v_1_phf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ROCK1	Pathway Commons Protein-Protein Interactions	1.0	null
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850491
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35827
BRD-K20398543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04666
8656_TAF1A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.835723
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51906
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3932
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.942542
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56802897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58005
CP-320650-01-3822	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23253
CRCGN008_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0406
Griscelli syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K66868536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03252
BRD-K49368687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06867
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.25329
K562_Valproic acid sodium salt_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023884
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13248
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28923
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23029982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51737
PMC10337103-13046_2023_2747_MOESM2_ESM.pdf-25-CREBZF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Barth syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMAD4	Pathway Commons Protein-Protein Interactions	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0357
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64487
Revesz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
NCI-H1437	GDSC Cell Line Gene Expression Profiles	1.0	1.8171
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3117
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69100231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85968
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K82002014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43984
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.922682
PRDX3	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31416
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01012
cii3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Gut granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.9191
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96856
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DTNBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MONOMAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09654
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13599
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20311
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PCI38	DepMap CRISPR Gene Dependency	1.0	2.03347
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50976
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNTB2	Pathway Commons Protein-Protein Interactions	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
JUND_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.40376
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876508
Bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
PMC11588659-41375_2024_2425_MOESM1_ESM.pdf-2-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064264
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05134
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834707
ALDOA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4512
BRD-K14151426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33004
K562_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160503
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9887
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71996
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04325
delsoline-5858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Aminoglutethimide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0256196
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00529
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAB	Pathway Commons Protein-Protein Interactions	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Host extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987909
BRD-K53221607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13025
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H345	GDSC Cell Line Gene Expression Profiles	1.0	2.09434
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01503
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9655
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
Aniridia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04013
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAD	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abomasum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
MCF-7 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.27952
bone disease	GWASdb SNP-Disease Associations	1.0	0.171999
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
CAL148	CCLE Cell Line Gene Expression Profiles	1.0	1.50371
CLTCL1	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Pelitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128974
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24896
other organism membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.202346
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phosphatidylinositol 3-kinase complex, class III, type II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4107
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
anemia	HPO Gene-Disease Associations	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11094
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31623
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.852
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52208
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
Vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.511
APPL2	Pathway Commons Protein-Protein Interactions	1.0	null
PSMA7	Pathway Commons Protein-Protein Interactions	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33624
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.85767
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74606
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194044
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02011
TRAPPC5	Pathway Commons Protein-Protein Interactions	1.0	null
GOLT1B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1187	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62691
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSA	Pathway Commons Protein-Protein Interactions	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438297
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01907
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18911
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
PREX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00383767
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21996934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35548
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAX1	Pathway Commons Protein-Protein Interactions	1.0	null
VAC14	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870285
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02837
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45663
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48303
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9903
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3940-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.836393
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
ANP32A	Pathway Commons Protein-Protein Interactions	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_SRT3025 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183805
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377898
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TEAD4	ENCODE Transcription Factor Targets	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01125
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881177
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46736
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7926_KD_ZCCHC8/ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.0907
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477557
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875809
ARAP3	Pathway Commons Protein-Protein Interactions	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.858961
Syndromic X-linked intellectual disability 94	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987099
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of leukocytes	HPO Gene-Disease Associations	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909518
MCF7_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167826
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endosome membrane	GO Cellular Component Annotations 2015	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39601
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0324
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015404
MAZ	ENCODE Transcription Factor Targets	1.0	null
TBC1D17	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02121
Intra-Golgi traffic	Reactome Pathways 2024	1.0	null
BRD-K32906083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3038
H3K36me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.00776
GSK3B_knockdown_202_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.77442
BRD-K74285424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52708
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biallelic	GeneRIF Biological Term Annotations	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
K562_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.024255
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bacterial Infection_Leukocyte - Monocyte - Macrophage (MMHCC)_GSE6435	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.14548
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862421
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54806
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A549_PJ34_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127717
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03089
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.164
commissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10298
hsa-miR-485-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
PRKAR2A	Pathway Commons Protein-Protein Interactions	1.0	null
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02901
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9478
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.732
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01422
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130235
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48363
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23677
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Navitoclax_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017256
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RAB18	Pathway Commons Protein-Protein Interactions	1.0	null
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855282
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.00258
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42428
GIMAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440191
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4881-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.06896
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.612419
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
helper T-lymphocyte	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-2.46345
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14698
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832025
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76497
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96072
CIB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PYGL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00331446
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4538
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.76941
BRD-K12011077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47731
Perturb_7931_KD_ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.35632
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12608
golgi apparatus	LOCATE Curated Protein Localization Annotations	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220644
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134813
LAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PADI4	ChEA Transcription Factor Targets	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86723
PUS1	Pathway Commons Protein-Protein Interactions	1.0	null
CORVET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.507
NF2	Pathway Commons Protein-Protein Interactions	1.0	null
MCM5	Pathway Commons Protein-Protein Interactions	1.0	null
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.54812
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855746
MAP2K2	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14525
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1264
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01232
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55065
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46248
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.08647
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882397
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12639
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50604
F5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53504
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K18623962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71579
BRD-K44139185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57452
BRD-K47370004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82405
OVCAR-8	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44616
CP-690334-01-3909	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106174
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
infants	GeneRIF Biological Term Annotations	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82571240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01307
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12682
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39369
PDX1-19855005-MIN6-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ESCRT-0 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07101
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55898
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09931
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35563
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS-53	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.37364
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7966
OCILY19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83295
infantile onset	HPO Gene-Disease Associations	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.854
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.851
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.644961
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
blast cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
K562_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176031
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17207
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4325
extraorganismal space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.184241
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.80123
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25832
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.11081
Perturb_11424_KD_KIF4A_SRP324259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EPHB2	Pathway Commons Protein-Protein Interactions	1.0	null
Golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.631
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325554
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563244
K562_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0244322
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F1_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31343
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33758
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Choline	CTD Gene-Chemical Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of lymphocytes	HPO Gene-Disease Associations	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLCB3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07464
BRD-K68320080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06058
BRD-K11057086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51375
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.587512
ARL2	Pathway Commons Protein-Protein Interactions	1.0	null
SR-95531-4820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09903
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.386
Mon1-Ccz1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.633
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910365
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46091
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17833
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08659289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3235
MCF7_Barasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179255
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15405
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UC-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857941
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99773
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hyperplasia	CTD Gene-Disease Associations	1.0	1.20881
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17547
Hermansky-Pudlak syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-NFKB1_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.775349
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80285
MCF7_PJ34_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149201
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
CP-690334-01-4383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21812
GSE198971_0_v_2_ncor2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6034
STAT3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33114
PICK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K21969044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11942
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918997
GD-46-OD81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512019
MCF7_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129203
TGFBRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
HUWE1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1568	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
RCOR1	ENCODE Transcription Factor Targets	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45154
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922389
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93429
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LK2	CCLE Cell Line Gene CNV Profiles	1.0	1.53605
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057472
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46779
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11661
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CISD2	Pathway Commons Protein-Protein Interactions	1.0	null
ANAPC7	Pathway Commons Protein-Protein Interactions	1.0	null
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11467
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43099
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-569	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-5	GDSC Cell Line Gene Expression Profiles	1.0	2.03016
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191318
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63353
SEC31A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11833
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.3
MCF7_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158312
RMI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636808
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255172
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12742
MCF7_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222066
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RB1	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11489
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46626
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1142
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
PARD6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2509
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K52735829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10956
BRD-K36352298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93041
Amorphous vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
K562_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149137
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983075
CUL3	Pathway Commons Protein-Protein Interactions	1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.35054
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41201
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37728
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12166
DGKQ	Pathway Commons Protein-Protein Interactions	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395612
KMS20	CCLE Cell Line Gene Expression Profiles	1.0	1.51031
JUND_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13618
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31068
Perturb_7956_KD_EXOSC3_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.95502
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS29	Pathway Commons Protein-Protein Interactions	1.0	null
SNTG1	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.2046
impaired	GeneRIF Biological Term Annotations	1.0	null
MC116	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.20491
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.20292
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.49003
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.940386
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Demeclocycline_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0159584
SIRT6	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20421
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955634
COG4	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Sodium Phenylbutyrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017953
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211311
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.8568
A549_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192182
PRPS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052313
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63483
hsa-miR-619	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877983
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_Streptozotocin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0264526
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21045
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.896607
MCF7_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139064
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169459
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51589
URGCP	Pathway Commons Protein-Protein Interactions	1.0	null
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.15763
GTEX-UJMC-1026-SM-4IHKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931356
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pheniramine-4012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14103
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.152
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17631
TRAPPC3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00354
DEF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056658
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11489
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.486
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDX1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.896731
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2161
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25443
Mononeme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal immunoglobulin level	HPO Gene-Disease Associations	1.0	null
SNX4	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54053991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03356
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45187
HMV-II	GDSC Cell Line Gene Expression Profiles	1.0	1.49404
CRX-20693478-ADULT_RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6316
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34074
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
betamethasone-dipropionate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15523
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.46864
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00041
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.48488
ELF1	ENCODE Transcription Factor Targets	1.0	null
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFPL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.837293
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837395
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38618
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845399
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.2059
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11981
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53886
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141347
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3713	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48293
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5640240-ppat.1006668.s013.xlsx-BETA4-379_common_elements_in_shEP400-1_BETA_shEP400-3_BETA_shMYCL_BETA_and_shEP400-2_BETA_BHLHE23	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0876
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Raltitrexed_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182582
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917401
K562_Thiotepa_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162047
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.877158
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
betonicine-3745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gingival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09479
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60837
KMS11	CCLE Cell Line Gene CNV Profiles	1.0	1.37116
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TUBB2A	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.93116
MCF7_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0208318
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7187
abnormality of cellular immune system	HPO Gene-Disease Associations	1.0	null
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34398
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045934
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
ZB-16-BR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317452
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.0386
TPM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870784
K562_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0228815
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.255107
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1658
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187668
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89113
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.868444
Endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.782
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940924
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Caov-4	GDSC Cell Line Gene Expression Profiles	1.0	1.80672
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67308
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K85656316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29191
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63406
H2369	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10496
BRD-K69337311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0403
S0-EE-Y79N_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359165
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P3H1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514797
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K97067262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6532
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06831
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98092
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26275
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7079
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.919853
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898427
MCF7_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221424
BRD-K99749624_linifanib_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.367006
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62779
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100605_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00257
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23161
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58501
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920981
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of body fluid levels	GO Biological Process Annotations 2015	1.0	null
STARD7	Pathway Commons Protein-Protein Interactions	1.0	null
HER2_KO_GDS4056_567_human_breast biopsies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1944
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of thrombocytes	HPO Gene-Disease Associations	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850445
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18987
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91728
K562_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016052
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208774
SARS-dORF6_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94881
BRD-K59544784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06144
Ferroxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194976
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.399
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	2.23779
PRKAA1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.22535
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20366
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PLEKHF2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31299
EGR1	ChEA Transcription Factor Targets	1.0	null
AA-86-YV75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.505426
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAP29	Pathway Commons Protein-Protein Interactions	1.0	null
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A42030853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2566
trafficking	GeneRIF Biological Term Annotations	1.0	null
RHOF	Pathway Commons Protein-Protein Interactions	1.0	null
Developmental and epileptic encephalopathy 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150154
BRD-K59041191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08955
SELENBP1	Pathway Commons Protein-Protein Interactions	1.0	null
A549_Valproic acid sodium salt_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151426
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02219
CHD2	ENCODE Transcription Factor Targets	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56461
cisplatin_homo sapiens_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Disulfiram_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119603
SH2D3A	Pathway Commons Protein-Protein Interactions	1.0	null
Conoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37868
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25235
A4-FUK	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.65886
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Merozoite dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35109
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22051
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307167
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5489
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910923
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
Mitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC73	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4724
BRD-K14399036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04328
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42679620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91876
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852153
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.672
3-hydroxy-DL-kynurenine-5641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239201
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22071
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.85429
ED-32-VE54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.536096
MCF7_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186451
Tubular endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
K562_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159079
K562_XAV-939_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0267838
MCF7_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183964
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02346
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548099
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75649
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
Congenital amegakaryocytic thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
hsa-miR-1	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
PSMD6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02782
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
MAFK	ENCODE Transcription Factor Targets	1.0	null
Perturb_7958_KD_ZCCHC8/ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.0228
Retromer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.941
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.977825
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56284
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-320-HSR	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
TUBA1A	Pathway Commons Protein-Protein Interactions	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09655
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974597
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07666
Diamond-Blackfan anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
PIK3R4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98165
LK2	CCLE Cell Line Gene Expression Profiles	1.0	1.42131
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76763044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26103
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84718
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8063
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.6149
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39327
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
K562_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201966
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36505
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59566
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27642
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05225
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
RHOA	Pathway Commons Protein-Protein Interactions	1.0	null
EF-33-QP63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281299
SEC22B	Pathway Commons Protein-Protein Interactions	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943019
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07383
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43568
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX14	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43782839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03136
CD28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487254
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
ACO2	Pathway Commons Protein-Protein Interactions	1.0	null
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Root hair tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323509
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAN	Pathway Commons Protein-Protein Interactions	1.0	null
LEMD3	Pathway Commons Protein-Protein Interactions	1.0	null
STXBP3	Pathway Commons Protein-Protein Interactions	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Severe congenital neutropenia 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.022
BRCA1	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18346
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.57699
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10573
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82460510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02255
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.23275
ERBB3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-57-USF2_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MCF7_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172475
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12145
BRD-K01853144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1692
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Thiotepa_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134571
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960587
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8074-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1032
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61186
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09092
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0311
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968718
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.903838
protein localization	GO Biological Process Annotations 2023	1.0	null
ZW10	Pathway Commons Protein-Protein Interactions	1.0	null
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08646
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81V-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-1226-SM-4GICA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07049
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4717
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.306
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.07576
Perturb_7923_KD_EXOSC3_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.17813
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
FKBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
DD-95-TY80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207212
BRD-K41532285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09638
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.961105
MCF7_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172114
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69273
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153054
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96693
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59833
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94343
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX8	Pathway Commons Protein-Protein Interactions	1.0	null
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06208
intracellular protein transport	GO Biological Process Annotations 2023	1.0	null
primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.253831
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99338
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86566
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907554
FOXM1	ENCODE Transcription Factor Targets	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27994
Tirabrutinib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0257604
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13669
CDK5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156619
Griscelli syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16638
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.292
BRD-K26395018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06707
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84275
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.72165
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6277
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833713
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3087
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.712103
UACC62	DepMap CRISPR Gene Dependency	1.0	2.00963
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15313
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52375
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14706855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47395
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00783
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66177
GTEX-WFON-1026-SM-4LVMD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0575
TRAPPC4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78017
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDFY1	Pathway Commons Protein-Protein Interactions	1.0	null
RAB20	Pathway Commons Protein-Protein Interactions	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.0294
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-A63759745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30111
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65238
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43181
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.982909
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07344
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53771043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12559
FOSL2	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4722-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
NCBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00831985
BRD-K32491833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22092
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865392
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29361
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250906
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4361
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.13822
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41895714_AS605240_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96142
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.37629
TMED1	Pathway Commons Protein-Protein Interactions	1.0	null
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07828
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158373
SYNCRIP_OE_GDS3186_84_mouse_wild type 129 mouse retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76596
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01707
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0548
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7269
BRD-K58237252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17116
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
antimycin A-5053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32876
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FGFR3_KD_GDS4454_79_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GAPVD1	Pathway Commons Protein-Protein Interactions	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8954
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Prostate adenocarcinoma_PRAD_TCGA-VN-A88Q-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9164468-13073_2022_1056_MOESM1_ESM.xlsx-S7_ARNT_alteration-hgnc_symbol_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.553905
FGD4	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	4.39945
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.336241
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266627
HAUS1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2665
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPT10	Pathway Commons Protein-Protein Interactions	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00763
SK-N-FI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0376
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukopenia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51489
Brown-Vialetto-Van Laere syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29901
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10138
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K38510068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26964
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95428783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04369
bromocriptine-5665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MCF7_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0277845
Atrophy	CTD Gene-Disease Associations	1.0	1.06261
Immunodeficiency 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17824
ELMO3	Pathway Commons Protein-Protein Interactions	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2424
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75752
STAT5B	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0255999
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1643
JHESOAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66568
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552035
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.505
implicate	GeneRIF Biological Term Annotations	1.0	null
VPS16	Pathway Commons Protein-Protein Interactions	1.0	null
SNAP23	Pathway Commons Protein-Protein Interactions	1.0	null
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
RMND1	Pathway Commons Protein-Protein Interactions	1.0	null
RAB2A	Pathway Commons Protein-Protein Interactions	1.0	null
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17207
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.399557
hsa-miR-99a-5p	MiRTarBase microRNA Targets	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5436
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264
MCF7_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161631
PMC3500769-srep00875-s3.xls-CEBP-Time_0_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30865566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56198
clathrin-coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
1941_CTPS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.602359
hsa-miR-548u	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
E2F6	ENCODE Transcription Factor Targets	1.0	null
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
CA46	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42545
Early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29439
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73518
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211474,GSE212779_8_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32525
JURL-MK1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.98686
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02336
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962161
Microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
ARID3A	ENCODE Transcription Factor Targets	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141829
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63068
ESCRT III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.164
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5967
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
gabapentin-7229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A60245366_AS-601245_A549_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29525414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38126
GSE140965_2_v_3_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Ki16425_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172672
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7873
K562_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200681
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
defective	GeneRIF Biological Term Annotations	1.0	null
ENO1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08196
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4629
BRD-A88381870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.022
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HB-24-AP80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420603
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45584
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96551
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176193
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adult stem cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323391
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.4421
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98253383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31904
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242567
MCF7_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222487
MEF2A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Danusertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113233
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975175
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22756
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARFGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9303
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.28387
CRCGN017_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1205
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390932
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0741
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964321
bidirectional	GeneRIF Biological Term Annotations	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03596
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12717
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
prilocaine-2352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6001
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.938
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48538
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61094
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61802
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04313
MCF7_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215612
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04121
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
BRD-K62369921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01806
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29688
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4126
MYOG	ENCODE Transcription Factor Targets	1.0	null
BRD-K98772859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08638
BRD-K02920459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10029
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.130728
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41714444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49568
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09189
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92308
GSE96544_1_v_0_mebendazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital diarrhea 7 with exudative enteropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0058
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.873566
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221026
PML	ENCODE Transcription Factor Targets	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82888
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19169
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.913782
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX12	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC-827	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the spleen	HPO Gene-Disease Associations	1.0	null
BAIAP2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
MCF7_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133802
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295918
K562_S-Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143059
Vesicle tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.353
13_AARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.889074
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30449
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.93613
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04377
Gastric mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93665
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29706
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4392
BRD-K79877849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30014
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COG5	Pathway Commons Protein-Protein Interactions	1.0	null
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03682
Basolateral recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02027
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48463
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50167
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.783307
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81344
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Prednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236864
BRD-K02675272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06919
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SEPT8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69664
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5956
PMC3500769-srep00875-s3.xls-GATA3-Time_4_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201523
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.455
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8666_TAF5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.34008
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60973
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43962
POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15076
K562_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155923
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12692
BRD-K80482221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58894
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.52222
7439_RPL15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.572924
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74541
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
hypergammaglobulinemia	HPO Gene-Disease Associations	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.12236
abnormality of b cells	HPO Gene-Disease Associations	1.0	null
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859112
ARPC4	Pathway Commons Protein-Protein Interactions	1.0	null
NPEPPS	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Belinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171864
BRD-K80066561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20496
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Golgi membrane	GO Cellular Component Annotations 2023	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08618283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05619
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24815
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871718
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3079
5089_NIFK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.723917
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843075
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190692
ATR	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14417
PMC6377303-NIHMS1504983-supplement-2.xlsx-AR_signature-To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93077
MCF7_Epothilone A_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155727
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
axes	GeneRIF Biological Term Annotations	1.0	null
K562_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023355
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49597
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
Congenital vertical talus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
SNX3	Pathway Commons Protein-Protein Interactions	1.0	null
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
VPS18	Pathway Commons Protein-Protein Interactions	1.0	null
CAB39	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3944-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
GTEX-VJYA-0626-SM-4KL1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983009
Pellicular membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.337
Infertility, Male	CTD Gene-Disease Associations	1.0	1.20295
BRD-K56469794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26962
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.015
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24713
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14002
DENND1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430218
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77646
BRD-K30823221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23855
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.852319
PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
Vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.697
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49092
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
protein transport	GO Biological Process Annotations 2015	1.0	null
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827372
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26685
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11552
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25397
MEF2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81033
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.986848
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74121
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61936
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
stomach	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.00738
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44084
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31007
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01616
LAN-6	GDSC Cell Line Gene Expression Profiles	1.0	1.56076
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.05936
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92446632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04273
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26265
BRD-K06208863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46636
splenomegaly	HPO Gene-Disease Associations	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.49774
BRD-K71419092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34736
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03642
BRD-K06459664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22711
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01536
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02073410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7475
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23386
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10709143-41556_2023_1271_MOESM7_ESM.xls-PAX7_Re-injury-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967531
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cyclic hematopoiesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.168
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0371074
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB25	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11336
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.109
BRD-K27982554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63385
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53655
GATA3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUDHL4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.83217
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.0778
neutropenia	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
7449_RPL23A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.502844
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
0173570-0000-4715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161457
HOS	GDSC Cell Line Gene Expression Profiles	1.0	1.61688
BRD-K96265882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32644
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90512
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043473
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GADD45GIP1	Pathway Commons Protein-Protein Interactions	1.0	null
0225151-0000-6384	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17561
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.86316
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4261
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513341
AP3S1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K49866832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02721
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16204
RAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-03-YQ91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213597
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
K562_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158475
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0926-SM-4DM5B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905041
RUVBL1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A77907596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68103
BRD-K25039453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34421
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03352
MCF7_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129263
Charcot-Marie-Tooth disease type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850491
BRD-K73355908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2022
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ESCRT II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.306
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84988
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0064
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04751
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36537572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67079
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CBX3	ENCODE Transcription Factor Targets	1.0	null
Myelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33702
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30221
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13633
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905128
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
golgi apparatus	GO Cellular Component Annotations 2015	1.0	null
Root vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
BRD-K14909006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43532
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981495
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3425
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79555
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874576
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
USE1	Pathway Commons Protein-Protein Interactions	1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.744542
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MPNST724	DepMap CRISPR Gene Dependency	1.0	2.05519
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TUBA3C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12132610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02654
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
Neoplasms	CTD Gene-Disease Associations	1.0	1.05386
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139247
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.042
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
post	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64129
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17543
NCI-H345	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28656917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65153
BRD-A37796306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14751
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73295
Auxin efflux carrier complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89569
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.2352
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15359
Apical hook	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49045
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cvt vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.081
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886852
organic substance transport	GO Biological Process Annotations 2015	1.0	null
PMC7553775-elife-61287-supp1.xlsx-Muller_2014_DREAM_bound_genes-Genes_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
thrombocytopenia	HPO Gene-Disease Associations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00823
TNFAIP8	Pathway Commons Protein-Protein Interactions	1.0	null
ABCF1	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911933
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57915
Dehydration_CNS - Brain - Hypothalamus (MMHCC)_GSE4130	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.09138
Acute Myeloid Leukemia_LAML_TCGA-AB-2888-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35444
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34517
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K87879912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64554
COG3	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03553
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207596
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38327
EGR1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Prednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150558
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32319151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11233
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01979
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71455
BRD-K80044183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42452
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334104
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998706
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN5	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74881
NAPA	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985257
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EPB41L5	Pathway Commons Protein-Protein Interactions	1.0	null
leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.756564
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10153
VAPA	Pathway Commons Protein-Protein Interactions	1.0	null
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FLI1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1246	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50487
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37015
Chloroplast outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55428
NCIH810	CCLE Cell Line Gene Expression Profiles	1.0	2.37255
7512_RPS23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.594113
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81394
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K84613654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22581
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83475
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.312437
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.18785
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826338
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08848
BRD-K99749624_linifanib_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565871
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49091
Almonertinib (mesylate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0242314
MCF7_Ellagic acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140259
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.586983
BRD-K00883748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14557
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107622
MCF7_Tanespimycin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00953886
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MCF7_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0366926
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coagulation	GO Biological Process Annotations 2015	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27639
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26543
Cvt vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.144
haloperidol-4468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_Patupilone_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180158
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9277
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60775
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KELLY	DepMap CRISPR Gene Dependency	1.0	2.00206
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.93447
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
imipramine-5440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K91197462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05361
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824439
BRD-K51919154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40078
Perturb_559_OE_NUP98HOXA10_SRP158432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.30596
SCAMP4	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217774
GOSR2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28721
megakaryocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149712
Mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Neutropenia, Severe Congenital, Autosomal Recessive 3	CTD Gene-Disease Associations	1.0	2.88009
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93588
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
serves	GeneRIF Biological Term Annotations	1.0	null
NAGLU	Pathway Commons Protein-Protein Interactions	1.0	null
EFM-192A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.28351
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962295
MCF7_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194723
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19601
Severe Congenital Neutropenia	DisGeNET Gene-Phenotype Associations	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02629
BRD-K16264250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14874
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13515
Cohen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
BRD-K18518344_Digitoxigenin_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53843
BRD-K33400588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66516
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76996
binding	GO Molecular Function Annotations 2015	1.0	null
SYK_druginhibition_281_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.14438
Primary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05637
P4HB	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03854
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.37897
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05817
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.38117
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.262
Diamond-Blackfan anemia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABP-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63058274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33085
dolichyl-phosphate-mannose-protein mannosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84151
MCF7_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124955
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02615
STAT5A	ENCODE Transcription Factor Targets	1.0	null
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A82843133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94689
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19778
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04165
BRD-K80577041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27092
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09275
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LRBA	Pathway Commons Protein-Protein Interactions	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18322
abnormality of blood and blood-forming tissues	HPO Gene-Disease Associations	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37404
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58442
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Subpellicular microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15532
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microcephalic osteodysplastic primordial dwarfism type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916614
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10735
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933893
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29513
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20095
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09424
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3861
BRD-K08534346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57464
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88516
BRD-K83902026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74161
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.91625
BRD-K73110675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43695
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02479
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NAPG	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.39867
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831738
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LPIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04598
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973267
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endoplasmic reticulum tubular network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57474
BRD-K28814368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35568
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18098
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7435
STAT1	ENCODE Transcription Factor Targets	1.0	null
families	GeneRIF Biological Term Annotations	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36096
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00363
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5027
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856584
MCF7_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144997
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22847
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846024
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38198
19204596-Table4	GeneSigDB Published Gene Signatures	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374902
BRD-K03015524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49921
NUMA1	Pathway Commons Protein-Protein Interactions	1.0	null
K562_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205145
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2023	1.0	null
TCF4-18268006-LS174T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Congenital Neutropenia, Myelofibrosis, Nephromegaly Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70239
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NEK6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NAAA	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
BE-71-AV63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362971
K562_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114704
NCI-H810	GDSC Cell Line Gene Expression Profiles	1.0	1.80566
ATF3	ChEA Transcription Factor Targets	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93436
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32502
BLOC1S4	Pathway Commons Protein-Protein Interactions	1.0	null
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63927
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0325203
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05675
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12108
MCF7_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159125
HOS	CCLE Cell Line Gene Expression Profiles	1.0	1.71688
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72802
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65489
ACAA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79866
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308875
extramedullary hematopoiesis	HPO Gene-Disease Associations	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058205
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01232
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46034
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18818
MAP1S	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142203
AARS	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7286-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35285
EBF1	ENCODE Transcription Factor Targets	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.025859
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42271016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23501
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.82735
BRD-K36096526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50519
PLEKHA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18263
BRD-K81647247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.768
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36785
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01922054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16729
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25908
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25964
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981635
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827552
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19783
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSIG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488426
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0769
BRD-K08438266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11631
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.435
bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.644586
AG-013608-5909	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78364
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1952
Garland cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
SETDB1	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SUDHL1	DepMap CRISPR Gene Dependency	1.0	2.06382
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
vacuolar part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.282189
Methionine	CTD Gene-Chemical Interactions	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.44288
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08613
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995239
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
hepatomegaly	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of b cell physiology	HPO Gene-Disease Associations	1.0	null
Clathrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.727
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845711
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.08059
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02253
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.30213
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058462
ATF1	ENCODE Transcription Factor Targets	1.0	null
severe congenital neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.915551
SNX15	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899042
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21454
CRCGN012_HEPG2_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76687
PDZD8	Pathway Commons Protein-Protein Interactions	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	3.2258
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4601-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAP2	Pathway Commons Protein-Protein Interactions	1.0	null
WDFY3	Pathway Commons Protein-Protein Interactions	1.0	null
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
BRD-K82930531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29398
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46626
HOOK2	Pathway Commons Protein-Protein Interactions	1.0	null
STEAP3	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RS4-11	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56445
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1780 (C21orf7)	NURSA Protein Complexes	1.0	null
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29371
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43977
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YWHAZ	Pathway Commons Protein-Protein Interactions	1.0	null
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930795
CTTN	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73604422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66165
Hematopoietic system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
A549_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0101524
TBC1D10B	Pathway Commons Protein-Protein Interactions	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22715
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.493775
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883886
K562_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227283
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thrombocytopenia	DisGeNET Gene-Phenotype Associations	1.0	null
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.529222
MCF7_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013689
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Familial Myelofibrosis	DisGeNET Gene-Disease Associations	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.86922
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13125
MON2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4474670__F3	PFOCR Pathway Figure Associations 2023	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911437
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.668395
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051309
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Microtubules	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
SMARCC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
promote	GeneRIF Biological Term Annotations	1.0	null
MCF7_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140371
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08242
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6611
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
irf1_17409403_nih3t3_gof_mouse_gpl81_gds2752	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.14412
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
KIAA0368	Pathway Commons Protein-Protein Interactions	1.0	null
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52434
PMC3500769-srep00875-s3.xls-GATA3-Time_0_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NEU1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43233
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.866
Infectious disease	Reactome Pathways 2024	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396878
ROCK1_knockdown_156_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.64606
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50477
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02486
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46291
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92687
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83342
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.89867
RAB21	Pathway Commons Protein-Protein Interactions	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227889
Cortical endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PJ34_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157523
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3607
H3K9me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33214
hsa-miR-499a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147659
Vacuolar transporter chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
BRD-K77004285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44079
Severe congenital neutropenia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.124
ILK	Pathway Commons Protein-Protein Interactions	1.0	null
RB1_KD_GSE50532_592_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09931
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.01286
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40512
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDX6	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01666
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08879
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36245
K562_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0258778
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93148
RHEB	Pathway Commons Protein-Protein Interactions	1.0	null
mucosa	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76900919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37069
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-36-FY37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200452
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871718
NFYA	ENCODE Transcription Factor Targets	1.0	null
CRX	ChEA Transcription Factor Targets	1.0	null
Yolk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70843
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
Clathrin coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
cisplatin_homo sapiens_gpl570_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPP2R1B	Pathway Commons Protein-Protein Interactions	1.0	null
NKIRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	0.345069
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286308
PDX1-19855005-MIN6-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2866-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28135
DA-17-YW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240858
CAOV4	CCLE Cell Line Gene Expression Profiles	1.0	2.85782
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834553
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35701
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14983
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36981
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PFI-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125118
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	0.881491
MCF7_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169912
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neutrophil	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18489
Perturb_6048_KD_PIAS2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SRF	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNE1	Pathway Commons Protein-Protein Interactions	1.0	null
U118MG_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.70302
SLC9A3R1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFN1	Pathway Commons Protein-Protein Interactions	1.0	null
STX4	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K76960970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75602
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.413382
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839544
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7925
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5468
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	1.0	1.76302
FGD3	Pathway Commons Protein-Protein Interactions	1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02157
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17625
BRD-K87419143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03192
hsa-miR-649	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MCF7_Tozasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164419
DHX29	Pathway Commons Protein-Protein Interactions	1.0	null
Early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.25
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857276
ACTC1	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2537_EIF2B3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.584232
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASNS	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212745
midodrine-1403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08472
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07827
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14567
BRD-K34117117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04207
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6773
MCF7_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146809
KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09248
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSK3A_knockdown_201_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.39862
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29358
SW620	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.929571
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969106
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00885
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932717
5005_METTL4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.798679
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173196
MCF7_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010442
A549_GSK J1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161373
hsa-miR-186-5p	MiRTarBase microRNA Targets	1.0	null
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
vesicle docking	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25182
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18431
VPS11	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30778
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07448
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIF3L1	Pathway Commons Protein-Protein Interactions	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62034
lateral terminal nucleus of the accessory optic tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1857
HOS	COSMIC Cell Line Gene CNV Profiles	1.0	2.25904
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18798
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51224
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65322
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56041932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20381
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lipoid proteinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK39	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
vacuole-mitochondrion membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900421
domperidone-5701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
synaptic vesicle	SynGO Synaptic Gene Annotations	1.0	null
u698	HPA Cell Line Gene Expression Profiles	-1.0	-0.878471
Ependymoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15557
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.51793
Neutropenia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00742
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08472
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
global developmental delay	HPO Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	1.41221
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50212643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71656
Cryptococcosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85484
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78821
CRCGN009_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02259
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92056
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FERMT2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85289
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11902
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09391
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35254
PPM1B	Pathway Commons Protein-Protein Interactions	1.0	null
STX17	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284806
K562_AG-490_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136819
Endosomal scaffold complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
Obesity in adult survivors of childhood cancer not exposed to cranial radiation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
PSMB2	Pathway Commons Protein-Protein Interactions	1.0	null
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.426
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.517756
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72336
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GA-30-HJ41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356746
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Extramedullary Hematopoiesis	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10174
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Amp_AA-TCGA-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV Infections	Reactome Pathways 2024	1.0	null
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367526
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Membrane coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.852
BRD-K25465939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28101
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03922
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934473
Poisoning	CTD Gene-Disease Associations	1.0	1.24812
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.635522
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61415
BRD-K83697352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68395
T3M4	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.924822
MCF7_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206535
BRD-K27870441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00362
PMC11637729-BJH-205-2450-s001.docx-0-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
cytoskeletal part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MYOF	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31202
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.866845
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04175
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.11962
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	0.843219
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913966
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918508
SNX5	Pathway Commons Protein-Protein Interactions	1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4728
KRT77	Pathway Commons Protein-Protein Interactions	1.0	null
EIF4G3	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275315
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.44994
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62779
BRD-K37680172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.461
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03796
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15524
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873117
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921202
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56524
VPS25	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64547
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13338
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1679
Liver Diseases	CTD Gene-Disease Associations	1.0	1.13381
GRM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429576
MCF7_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163562
16715129-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.261
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05707
MCF7_Fedratinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158446
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KA4	Pathway Commons Protein-Protein Interactions	1.0	null
Sorting endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.645
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2198
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.786491
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837209
tetramisole-2489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Protein storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
GTEX-OXRL-0726-SM-3NM9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833169
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29677
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28882
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_239_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218613
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837478
A549_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015015
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01446
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00734
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8662
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0726-SM-4LVM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880879
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32605
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88593
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43373
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27878
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.15606
abnormal germ layer development	MGI Mouse Phenotype Associations 2023	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859874
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
BRD-K94771818	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0438
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920189
CCL20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541532
TAL1	ENCODE Transcription Factor Targets	1.0	null
SHP77	CCLE Cell Line Gene Expression Profiles	1.0	1.77135
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
494_ARID4B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.521972
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3386
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48288
GTF3C4	Pathway Commons Protein-Protein Interactions	1.0	null
ID-00-IC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.679754
ZFYVE20	Pathway Commons Protein-Protein Interactions	1.0	null
NME2	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.52345
hsa-miR-15a-5p	MiRTarBase microRNA Targets	1.0	null
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9835
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72193
K562_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154633
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200374
Entecavir (monohydrate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0191021
A549_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127951
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_303_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.37023
SLC30A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12795
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl550_gds848	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DUSP3	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13375
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G6PD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91572
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69992
DA-58-LZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267357
Plastid outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27962
A549_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126768
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917146
K562_PF-573228_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182011
X-linked dyserythropoietic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FAM213A	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19493
MCF7_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0268028
lateral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54211
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.76514
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72319
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.543
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3506
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34982
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00364
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CP-320650-01-3825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ITPK1	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K06335310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15993
7559_RRN3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.528982
A549_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0320746
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89476396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3295
Lung adenocarcinoma_LUAD_TCGA-55-6971-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47791
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229618
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25177
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973394
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898207
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.663181
endosome	GeneRIF Biological Term Annotations	1.0	null
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
transport	GeneRIF Biological Term Annotations	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76951
FD-79-TC61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202201
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882355
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5933
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_7927_KD_ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.5193
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.81102
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STK38	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5269
Brain Lower Grade Glioma_LGG_TCGA-DH-5142-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANP32E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0041761
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22756
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TUBA1B	Pathway Commons Protein-Protein Interactions	1.0	null
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255787
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48263613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02822
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16101
benzylpenicillin-3577	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05765
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atf1-pcr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
CRCGN015_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53565
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.480855
GARS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A88237615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52463
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825063
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.889226
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lidocaine (hydrochloride)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0238242
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40975
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79555018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07027
BRD-K25773863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23786
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21369
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB9A	Pathway Commons Protein-Protein Interactions	1.0	null
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
onset	HPO Gene-Disease Associations	1.0	null
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351856
RAB43	Pathway Commons Protein-Protein Interactions	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.979959
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417355
MCF7_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184881
BRD-K23435841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15329
p3 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00483
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.503
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29253
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
XPO5	Pathway Commons Protein-Protein Interactions	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHP-77	GDSC Cell Line Gene Expression Profiles	1.0	2.66799
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.393799
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1187	GDSC Cell Line Gene Expression Profiles	1.0	2.15847
BRD-K44141416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66186
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.480855
Autosomal recessive distal hereditary motor neuronopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20956
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BL6647 (EPS15)	NURSA Protein Complexes	1.0	null
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.19205
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043527
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.379276
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K18856772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11112
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59293
Distal tip cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98703
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6715
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206173
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845319
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLDA3	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-WK-A8XZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460499
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211474,GSE212779_8_v_4_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85112
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016291
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80304
mafenide-5499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
MCF7_Raltitrexed_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144332
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tobramycin-4162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47048
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.28906
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139967
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36653
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A64374397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01191
K562_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189685
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.24843
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6389
CRCGN012_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09949
CRCGN015_MCF10A.TP53.M_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2519
Endocytosis	KEGG Pathways 2026	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879001
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13018
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4786-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE126463_5_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
suffered	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90018
DA-07-LL18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241849
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12841150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05111
BRD-A04691170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00674
PACSIN2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41886
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907554
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0746
GANAB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K56343202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41406
A3KAW	CCLE Cell Line Gene CNV Profiles	1.0	1.59776
BRD-K12612468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18386
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
estradiol-4432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153055
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835469
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78718
RHOG	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6435
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835855
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endosome	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PYGB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31531
MYC	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13697
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7391
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V1C2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1227	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21059010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40906
MCF7_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148954
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91607
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193011
PRPF8	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978898
Growth hormone insensitivity syndrome with immune dysregulation 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92204
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.921872
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0128
macelignan	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32318
Arrhythmogenic right ventricular dysplasia 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA-73-BW50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401564
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0496
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949783
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33375
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39017
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0841
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null