association	dataset	threshold value	standardized value
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98155
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16234
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1636
PL18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1847
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47275
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45311
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38014
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06708
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943445
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
HCC2450	DepMap CRISPR Gene Dependency	1.0	2.0016
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44425
ZNF384	ENCODE Transcription Factor Targets	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7753
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28463
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24327
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78248
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
b-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42979
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16517
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7623
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05681
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92879
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_11240_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3242
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161139
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944725
Lung adenocarcinoma_LUAD_TCGA-99-8032-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59436
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10507
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
artery disease	GWASdb SNP-Disease Associations	1.0	0.345351
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.117171
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55283
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85099
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7469
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02232
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894186
lymph	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
extrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.255372
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1206_KO_Sp3_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19093
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04832
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70228
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17575
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840505
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49116
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13491
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32285
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881801
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75342
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45396
NB69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920551
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50722
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9126
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5521
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3088
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51812
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4067
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7607
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10144
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81365
DB	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL11A	ENCODE Transcription Factor Targets	1.0	null
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.52712
Childhood type dermatomyositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45208
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40015
Endolysosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09655
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51804
GSE211474,GSE212779_8_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5263
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15553
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.268845
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94046
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.57114
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13919
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17462
uric acid	GAD Gene-Disease Associations	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847328
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75259
PHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03024
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899302
E2F4	ENCODE Transcription Factor Targets	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Spleen-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	4.60813
MDA-MB-468	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71089
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55466
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02682
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82646
GSE102342,GSE102648_1_v_0_curcumin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.31322
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
binding	GO Molecular Function Annotations 2015	1.0	null
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WD40/YVTN repeat-like-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.394
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68582
Drug Toxicity	HuGE Navigator Gene-Phenotype Associations	1.0	null
Airway responsiveness in chronic obstructive pulmonary disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961918
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825035
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847333
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tick-borne encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09927
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7214
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51883
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
p53 decamer	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887265
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61403
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3356
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39759
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22483
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86097
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46504
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89596
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7128-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16682
NB1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68225
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	89.8887
GSE211744_2_v_1_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58754
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lymph	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09991
HNRNPL_02_160	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.52356
KMRC1	CCLE Cell Line Gene CNV Profiles	1.0	1.49551
PMC10492032-mmc2.pdf-11-BATF2_BATF2	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45422
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31939
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16591
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19375
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35837
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
Behcet Syndrome	dbGAP Gene-Trait Associations	1.0	0.199407
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5429
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65203
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.132693
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50046
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.21318
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.37892
SW626	DepMap CRISPR Gene Dependency	1.0	3.51219
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4754
lipoproteins	GAD Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5699
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01228
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47574
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75879
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79448
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30111
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02329
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03115
NB10	DepMap CRISPR Gene Dependency	1.0	5.07825
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20625
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3313
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations	1.0	0.483518
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55878
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
aorta	GAD Gene-Disease Associations	1.0	null
SNX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54674
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96809
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050032
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55488
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3165
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04756
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
Lung adenocarcinoma_LUAD_TCGA-78-7536-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.28905
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10761
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01476
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93472
BOLA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93282
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
autoimmunity	GWASdb SNP-Phenotype Associations	1.0	0.97962
HCC44	DepMap CRISPR Gene Dependency	1.0	2.32163
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70619
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03214
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21081
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87144_3_v_1_rorc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Dermatomyositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49604
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18726
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994379
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67918
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83504
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17934
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34696
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49379
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.10383
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52695
b-lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32535
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81313
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.126
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91066
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874461
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10543
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	1.0158
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38014
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.938103
Perturb_3404_KO_miR144/miR451_SRP373681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34853
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07243
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17088
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19062
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09188
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9789
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
G-292_CLONE_A141B1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968961
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
leukocyte disease	GWASdb SNP-Disease Associations	1.0	0.329092
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6784
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932087
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05367
Perturb_11514_KO_Il9r_SRP318774	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.40649
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892279
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ART5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40507
PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38802
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.157
BICR78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967537
lipid binding	GO Molecular Function Annotations 2015	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
antidepressive agents	GAD Gene-Disease Associations	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11741
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995074
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04973
kidney disease	GWASdb SNP-Disease Associations	1.0	1.12892
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37193
UMUC3	DepMap CRISPR Gene Dependency	1.0	2.34933
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.93541
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45885
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92719
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839358
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2713
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35088
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05751
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00701
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73397
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUDHL6	CCLE Cell Line Gene Expression Profiles	1.0	1.37995
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lupus erythematosus	GWASdb SNP-Disease Associations	1.0	1.64762
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850715
Human - Lung v2 (HLCA) - Finest - DC1	HuBMAP Azimuth Cell Type Annotations	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845532
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8258
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crouzon syndrome-acanthosis nigricans syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25502
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.888762
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00594
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51326
hsa-miR-551b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.32148
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35481
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90407
NCI-H2405	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32568
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47409
OSC-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3666	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
GSE146253_0_v_2_stat4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
NFYB	ENCODE Transcription Factor Targets	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14296
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
arteriosclerotic cardiovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835097
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
B-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.03731
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-NCOA3_mod_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
mental depression	GWASdb SNP-Disease Associations	1.0	1.28906
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4953
GSE211128_2_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24652
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60705
Lupus Erythematosus, Systemic	dbGAP Gene-Trait Associations	1.0	1.02473
PMC3432194__F2	PFOCR Pathway Figure Associations 2023	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phagocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-146a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11826
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83834
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917173
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6912
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
GSE90019,GSE90020_1_v_3_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34462
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.91059
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44769
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	87.6582
vascular disease	GWASdb SNP-Disease Associations	1.0	0.313856
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02496
grhl3_16949565_skin_lof_mouse_gpl1261_gds2629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.146647
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHSA0011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcosine oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.991129
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17849
GSE183101_0_v_1_hvcn1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.364215
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838299
Perturb_7107_OE_Mir378A_SRP047487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.81076
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99918
Lymph	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.426
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
population	GeneRIF Biological Term Annotations	1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	6.12695
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59436
TN2	DepMap CRISPR Gene Dependency	1.0	2.03719
dorsolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01508
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60279
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	1.99325
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lupus	GeneRIF Biological Term Annotations	1.0	null
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
Brain Lower Grade Glioma_LGG_TCGA-HT-7601-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
erythematosus	GeneRIF Biological Term Annotations	1.0	null
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRX1_01_227	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60023
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839224
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18837
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01438
Entorhinal area, medial part, dorsal zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68225
ABL1_druginhibition_77_GSE24493	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.44367
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54458
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83681
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00493
hsa-miR-3944-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE172020_1_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
NP-69 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905608
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04587
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3362
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42044
PMC8144624-41598_2021_90212_MOESM2_ESM.xlsx-3_hrs_ps_LPS-merged_Gene_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21982
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
CHD2	ENCODE Transcription Factor Targets	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.09751
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56827
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57363
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49691
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0507
abnormal neutrophil cell number	GWASdb SNP-Phenotype Associations	1.0	0.630475
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0231
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70707
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02389
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.81858
PMC7616765-EMS198548-supplement-Data_S2.xlsx-3_DEG_2D_and_3D-D9_Up_in_3D_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	5.14726
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02597
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08955
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
Perturb_16680_Mut_Jak3_SRP168570	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNU1076	DepMap CRISPR Gene Dependency	1.0	2.88871
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37781
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23642
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32121
NCI-H2170	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63178
HCC1599	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46397
vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56273
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826563
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14862
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20033
Perturb_16663_KO_Zfp36/Zfp36l1_SRP273454	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.84856
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13667
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40015
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58577
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53553
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48697
SUP-HD1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.95801
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72551
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190186,GSE190188_0_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21277
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05878
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25947
Perturb_3352_KO_Ahr_SRP285760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.32926
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31796
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01692
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15158
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865225
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC5731741__F4	PFOCR Pathway Figure Associations 2024	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5516
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A51Y-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885041
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850289
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91225
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53234
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
CJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.815
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21124
layer 2 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28116
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lipoproteins	dbGAP Gene-Trait Associations	1.0	0.867795
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24931
18160665-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13805
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11763
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29677
NUGC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75759
Macrophage_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
NCI-H647	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3057
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18116
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
abnormality of cholesterol metabolism	GWASdb SNP-Phenotype Associations	1.0	0.721729
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.074522
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13268
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.74894
PC3	DepMap CRISPR Gene Dependency	1.0	3.06188
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substance abuse	GWASdb SNP-Disease Associations	1.0	0.410854
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09829
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells -  7 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200446_0_v_3_srsf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16502
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47997
bone disease	GWASdb SNP-Disease Associations	1.0	0.30908
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65978
Perturb_9773_KO_Tkt_SRP313974	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.2129
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4295	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65242
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26217
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920674
Thymus-dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.194701
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07739
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.885
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36643
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
Stroke	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24743
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826864
MS751	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870539
Perturb_15341_KI_ORP4L_SRP367235	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4675
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9464
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.37968
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78105
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.13151
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5181
MAFK	ENCODE Transcription Factor Targets	1.0	null
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
endosomal transport	GO Biological Process Annotations 2015	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.06458
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.72858
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898254
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971784
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08778
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7632
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872166
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06846
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31153
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07621
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27801
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36139
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15859
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2858
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_5_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44384
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01508
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
Lung-dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0993378
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24676
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42421
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88277
Presubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79138
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.3335
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03141
RD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99393
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34462
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79927
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.28353
Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122509,GSE122513_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07053
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886356
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A6JB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899087
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14108
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5711528__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86161
immune system disease	GWASdb SNP-Disease Associations	1.0	0.16003
Aorta, Abdominal	dbGAP Gene-Trait Associations	1.0	0.443956
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.36221
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Isolated growth hormone deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890019
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959795
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866063
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3222
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26439
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
PMC2742312-1479-7364-3-3-221-S3.PDF-206-ZNF248_ZNF248	Rummagene Transcription Factor Associations 2026	1.0	null
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51274
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40277
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.0317
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20406
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866063
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37161
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37781
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902506
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.60812
t69-brown-adipose_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	6.06946
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.197777
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
u698	HPA Cell Line Gene Expression Profiles	1.0	1.03702
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46694
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subiculum, ventral part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.18921
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.11297
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25101
KDM5B	ENCODE Transcription Factor Targets	1.0	null
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
OXCT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67987
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872107
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27359
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26398
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
yy1	GeneRIF Biological Term Annotations	1.0	null
PH-BEACH domain	InterPro Predicted Protein Domain Annotations	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
ICC4	DepMap CRISPR Gene Dependency	1.0	2.49243
KON	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21789
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823938
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21274
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879835
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17291_OE_lncRNA5251_SRP239064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.04906
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47449
Muscle tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
Myopathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52605
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95882
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5182-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.895087
Perturb_10731_KO_Nr1h4_SRP299252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58771
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
moderate generalized osteoporosis	GWASdb SNP-Phenotype Associations	1.0	0.938103
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4330-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06401
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01508
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9471
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05681
Glucose	dbGAP Gene-Trait Associations	1.0	0.108126
RB1_KD_GSE50532_627_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53265
Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
lymph	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51266
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838019
PMC4022581__F4	PFOCR Pathway Figure Associations 2023	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15503
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10954
Scoliosis, Isolated, Susceptibility To, 3	DisGeNET Gene-Disease Associations	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24931
ds19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69182
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	1.3974
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11213_OE_arcA_SRP351667	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.76257
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENL-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49276
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22105
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
KCTD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10243
Cholesterol	dbGAP Gene-Trait Associations	1.0	0.185527
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16495
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906446
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48576
WD40 repeat	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05417
Perturb_3299_KO_Bmpr1a_SRP116199	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.9964
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03256
RUNX1_01_245	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59446
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09443
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38014
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6BE-01A-41R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09241
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21413
Perturb_4544_KD_Ehmt1_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.91809
pyramidal layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79138
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99372
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03915
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01499
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08231
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4417-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901872
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2218	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
170MGBA	DepMap CRISPR Gene Dependency	1.0	2.82787
presubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59436
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70747
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gray platelet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
single-organism localization	GO Biological Process Annotations 2015	1.0	null
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33723
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51244
Human - PBMC - L3 - Conventional Dendritic Cell 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09318
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35084
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07786
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973417
Perturb_5235_KO_Ncor2_SRP222273	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.68286
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.487607
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_11_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE254848_9_v_8_ptges_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46724
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3378-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.72858
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS633T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95307
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7825356-8844261.f3.docx-48-EN2_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
body mass index	GAD Gene-Disease Associations	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.105041
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27101
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998637
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88527
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5263
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20012
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C-4-I	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.85376
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927557
hsa-miR-4666-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03961
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12374
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27082
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45495
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00458
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23078
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57647
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11954
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09866
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	1.41904
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63573
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASPSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92256
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829486
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.523045
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44875
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969562
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970995
RKO	CCLE Cell Line Gene CNV Profiles	1.0	1.59853
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
DCLRE1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88938
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02651
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.2861
decreased erythrocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.71383
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.19223
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5321
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
endomembrane system	GO Cellular Component Annotations 2015	1.0	null
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02597
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94843
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5249-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC0813	DepMap CRISPR Gene Dependency	1.0	2.0322
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PC3	CCLE Cell Line Gene CNV Profiles	1.0	2.05818
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43313
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.8003
PMC8047323-Table_3.xlsx-Venn_581_LPS_T24_vs_LPS_T0-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61266
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.942181
mantle zone of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96371
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0504
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36289
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.4793
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24222
Perturb_11184_KO_Jmjd1c_SRP239229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.22353
NCI-H650	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.69031
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16682
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20475
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22392
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95307
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SF268	DepMap CRISPR Gene Dependency	1.0	3.01473
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92719
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992289
granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.345926
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8449
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978839
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866063
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67102
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45377
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20692
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.363421
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12107
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02118
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00096
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14451
YH-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994293
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09348
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91864
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1229
all	GWASdb SNP-Phenotype Associations	1.0	0.101308
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837448
Primary biliary cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7385-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4543_KD_Chd4_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.20616
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
GSE223008_0_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-5398-01A-02R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19139136-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial pallium (hippocampal allocortex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22063
Chediak-Higashi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
Subiculum, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44029
TPRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.804
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03692
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_0_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1054
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.085437
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849509
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.785384
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.165995
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14952
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999384
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04168
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18078
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889368
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5633-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27474
PMC4013678__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42628
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.45877
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
downregulating	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0993
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43939
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20931
MHC class I peptide loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the upper arm	GWASdb SNP-Phenotype Associations	1.0	0.904359
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35845
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.057316
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.67947
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.295129
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.826866
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1818
Retrohippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96371
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.204607
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24621
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9856
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.977477
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24909
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03604
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3968
mbl2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.891395
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07339
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04321
genotype	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01478
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_10882_KO_Pck1_SRP363462	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64966
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09253
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56059
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98647
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968986
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC4022581__F4	PFOCR Pathway Figure Associations 2024	1.0	null
ADNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04737
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4579
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1545
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31153
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11171
Armadillo-like helical	InterPro Predicted Protein Domain Annotations	1.0	null
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845965
OAW42	DepMap CRISPR Gene Dependency	1.0	2.75731
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
NCIH524	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61898
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10836
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19983
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02341
RHBDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5291
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07701
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66119
Subclinical atherosclerosis traits (other)	GWAS Catalog SNP-Phenotype Associations	1.0	0.165905
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	3.42932
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79214
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
PMC8489726-pbio.3001394.s016.xlsx-B-ZEB1_peaks-SYMBOL_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08496
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.45152
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1448
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bone resorption disease	GWASdb SNP-Disease Associations	1.0	0.478169
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
RETREG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51505
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91202
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84123
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0788
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU46	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40438
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01582
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09675
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60866
STAT5A	ENCODE Transcription Factor Targets	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21737
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.782
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57442
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30259
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2756
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10113
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-130b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52963
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16693
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11033188-mmc3.pdf-2-TFEB_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04087
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88711
chr10_48725929_T_C_b38	GTEx eQTL 2025	1.0	2.49523
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4176
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0755
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20619
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56873
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4548
systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06942
CBFB_01_43	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.4132
hsa-miR-548u	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE150665,GSE150667_1_v_5_mysm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956687
Liver-liver dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.106648
H4C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81879
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.15201
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Subiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31153
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20487
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Response to antidepressant treatment	GWAS Catalog SNP-Phenotype Associations	1.0	0.314454
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13657_KD_CCND3_SRP325057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.16112
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91832
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1562
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04227
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
Antidepressive Agents	dbGAP Gene-Trait Associations	1.0	0.609816
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.501063
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-NCOA3_mod_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88504
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871913
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27616
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92073
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07562
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Human - Kidney - L2 - Classical Dendritic	HuBMAP Azimuth Cell Type Annotations	1.0	null
KG1	CCLE Cell Line Gene Expression Profiles	1.0	1.37952
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.845646
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935583
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056198
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08063
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45103
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GFPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961811
SOX9	ChEA Transcription Factor Targets	1.0	null
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.881735
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
TAF1	ENCODE Transcription Factor Targets	1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1641
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875701
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10597
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-PRRX1-sequence_name_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79138
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41324
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77891
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80273
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
Interferon regulatory factor 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.753
immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41644
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83231
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
SDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38446
NCIH1930	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09848
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939145
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11086_KO_Atf6_SRP332137	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.54835
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23747
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04973
Perturb_16459_KO_Nf1_SRP155510	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.75986
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
systemic lupus erythematosus	GWASdb SNP-Disease Associations	1.0	1.64762
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24186
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12985
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896278
CDX2-19796622-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.968538
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.28905
biological_process	GO Biological Process Annotations 2015	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.233738
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952323
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
PMC10350077-media-8.xlsx-PPM1D_tr_LPS_enriched_Up_KEGG_-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.697
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1483
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964457
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
Perturb_10733_OE_Sirt6_SRP282071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.1192
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833403
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32555
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874641
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.07945
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13439
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.973211
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14498
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.35138
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBC2142 (ESCO1)	NURSA Protein Complexes	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.78236
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-454	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0145
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0377
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	1.07052
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96696
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49405
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
systemic lupus erythematosus	GWASdb SNP-Phenotype Associations	1.0	1.52026
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868512
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938291
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38014
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8032
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973417
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0824
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4823830-ncomms11171-s2.xlsx-GATA3_repressed_genes-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06922
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53669
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03378
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17841
TSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.722077
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1698
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05386
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05318
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210580_5_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.740245
hypertension	GWASdb SNP-Disease Associations	1.0	0.893803
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849368
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04073
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16591
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73025
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39441
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uric Acid	dbGAP Gene-Trait Associations	1.0	0.582442
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86809
Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9035
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63437
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1925
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23607
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
hypersensitivity reaction disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6042
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09518
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53166
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52851
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27232
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89327
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91225
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975883
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10946_KO_Nr1d1_ERP117724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.83312
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
SARS-dORF6_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.19515
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
neutropenia	GWASdb SNP-Phenotype Associations	1.0	0.630475
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25967
TMEM98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24459
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PECAPJ15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60325
aorta, abdominal	GAD Gene-Disease Associations	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925502
lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95307
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31153
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976031
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.12469
UM-UC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05499
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38014
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_3_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
WM278	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18108
runx1_18671852_e8dot5_lof_mouse_gpl1261_gds1511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.27641
overnutrition	GWASdb SNP-Disease Associations	1.0	0.478169
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5053
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00416
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27533
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865133
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03101
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82355
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ab_N_YW (RFWD3)	NURSA Protein Complexes	1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.61623
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19807
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71205
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62243
AHR	ChEA Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00024
Conventional dendritic cell 1(cDC1)_Skin_Human	CellMarker Gene-Cell Type Associations	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03115
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.956
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5181
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25202
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.884565
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69335
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0969
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07339
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954152
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889923
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184902_3_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857508
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
a72	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1594
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40015
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04973
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3132
Perturb_3327_KO_miR23_SRP092642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
GB1	CCLE Cell Line Gene CNV Profiles	1.0	1.49586
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44425
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4217
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03405
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60358
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07144
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48506
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15903
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.47945
RL	CCLE Cell Line Gene Expression Profiles	1.0	2.40899
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50624
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDK8	Kinase Library Serine Threonine Kinome Atlas	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914268
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of neutrophils	GWASdb SNP-Phenotype Associations	1.0	0.382642
Brain compression	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15945
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.174
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04815
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00684
Polymyositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22494
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25241
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAN-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883311
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45539
GSE184902_3_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01508
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91933
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
WD40 repeat, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43294
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49862
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5792
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8379
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.837139
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979906
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular transport	GO Biological Process Annotations 2015	1.0	null
PMC10709142-41556_2023_1281_MOESM2_ESM.xlsx-Supplementary_Table_1-CLUSTER_2_MAF_downregulated_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50386
ACHN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.52603
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	0.292002
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2087
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monocyte-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.347
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1197
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17538
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990396
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.294119
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04308
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58788
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
MC116	CCLE Cell Line Gene Expression Profiles	1.0	1.95892
BL-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7614775-EMS178742-supplement-Proteomics_Table_1.pdf-201-ZNF318_ZNF318	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09356
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26668
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43614
abnormality of macrophages	GWASdb SNP-Phenotype Associations	1.0	0.311286
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850116
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0145
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19986
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0223
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.72283
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15712
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	1.35037
blood	GTEx Tissue Gene Expression Profiles	1.0	1.32873
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10686
CFPAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06556
JQ006 (MSH2)	NURSA Protein Complexes	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04316
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30767
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.95622
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28379
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19409
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02488
FOXO3	ChEA Transcription Factor Targets	1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.265162
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973417
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05126
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00024
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
Perturb_1912_KO_Prkcd_SRP386893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.43295
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04973
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.356732
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4116
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64743
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_Myeloid-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.108791
Perturb_1751_KD_lncRNA12928_SRP174348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.57804
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
CAOV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
atherosclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46724
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL1-CLOSEST_GENE_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10017
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923949
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.4992
line14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
asian	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1995
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Human - Kidney - L3 - Classical Dendritic	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC10492032-mmc1.pdf-1-BATF2_BATF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
ets1	GeneRIF Biological Term Annotations	1.0	null
obesity	GWASdb SNP-Phenotype Associations	1.0	0.938103
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	0.121957
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13368
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17402
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21062
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07164
ETS1	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE103124_2_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lymphnode	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01478
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57664
TCF12	ENCODE Transcription Factor Targets	1.0	null
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41299
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16317
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26956
osteoporosis	GWASdb SNP-Disease Associations	1.0	1.07052
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942442
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830497
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100863,GSE100864_3_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8489726-pbio.3001394.s016.xlsx-E-Gene_Overlap-43_elements_included_exclusively_in_ZEB2_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
ELK1	ENCODE Transcription Factor Targets	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CA9-22	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52782
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973396
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04946
RND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41517
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14489
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.04841
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89089
Brain Lower Grade Glioma_LGG_TCGA-CS-6290-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.942719
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29444
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857938
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841464
MOG-G-UVW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24008
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866063
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34316
RFX5	ENCODE Transcription Factor Targets	1.0	null
Perturb_2016_KO_Hdac3_SRP360955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20716
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88864
P38G	Kinase Library Serine Threonine Kinome Atlas	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD141+CLEC9A+ dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42082
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Human - Adipose - L2 - hcDC1	HuBMAP Azimuth Cell Type Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33892
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
IRF4	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07666
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3895
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31857
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50016
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0451
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846722
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	7.47339
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.421487
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0876
KAT2A	ENCODE Transcription Factor Targets	1.0	null
smoking cessation	GAD Gene-Disease Associations	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04893
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973896
PMC5725737-IJC-142-297-s013.xlsx-DTC_mna_vs_TUM_mna-DTC_MYCN-high_vs_TU_MYCN-high_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Conventional dendritic cell 1(cDC1)_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62465
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.45248
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83908
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06462
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8307
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40455
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875589
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20656
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94644
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3877
hsa-miR-376b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HDAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49941
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26394
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01471
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32933
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
C8-MEF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32798
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.175175
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-3.25157
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40049
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1_01_322	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.77131
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56702
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
Amyopathic Dermatomyositis	DisGeNET Gene-Disease Associations	1.0	null
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
JHH-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86809
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44855
OVK18	CCLE Cell Line Gene CNV Profiles	1.0	1.49761
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40708
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6868
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57497
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16844
hsa-miR-3651	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89635
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
OVKATE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2746
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.410854
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28468
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4263
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956055
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.87
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
snp	GeneRIF Biological Term Annotations	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Clinically amyopathic dermatomyositis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
SPI1	ENCODE Transcription Factor Targets	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8629
depression	GWASdb SNP-Phenotype Associations	1.0	1.12851
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74624
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31527
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915012
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04762
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Flemming body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73059
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.015
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.52211
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88644
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	2.65289
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11324
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42581
mantle zone of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01508
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55791
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436822
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97352
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35116
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4390_KO_AMBRA1_SRP251921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.24347
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832403
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05452
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.99325
lipid metabolism disorder	GWASdb SNP-Disease Associations	1.0	0.826866
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.623
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
Congenital myasthenic syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
systemic lupus erythematosus	GAD Gene-Disease Associations	1.0	null
GPR160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82315
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09067
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22257
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67151
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217982,GSE217983_2_v_3_hgfac_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14746
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.043
hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941583
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979091
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2647
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
hypersensitivity reaction type ii disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22132
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02537
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96372
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65971
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50865
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06922
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08881
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43674
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06911
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
GSE110300,GSE110304_0_v_1_estradiol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
KYSE150	DepMap CRISPR Gene Dependency	1.0	2.23773
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45647
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6463
CEBPB	ENCODE Transcription Factor Targets	1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06805
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0035
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54056
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8931
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81319
LPS6	DepMap CRISPR Gene Dependency	1.0	2.81161
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_up-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45705
phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
Occult macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41947
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.30768
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
M07E	DepMap CRISPR Gene Dependency	1.0	2.18935
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77717
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02263
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982274
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953803
GIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33838
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05834
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.27771
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80918
POU2F2	ENCODE Transcription Factor Targets	1.0	null
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07301
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL2264 (DOCK9)	NURSA Protein Complexes	1.0	null
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908501
OCILY3	CCLE Cell Line Gene Expression Profiles	1.0	1.60217
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF8-22096565-A-GC-B-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
vasculitis	GWASdb SNP-Disease Associations	1.0	0.394614
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17392
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Adolescent Idiopathic Scoliosis	DisGeNET Gene-Disease Associations	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.083571
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05607
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858167
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8752
C4II	DepMap CRISPR Gene Dependency	1.0	3.15349
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.54251
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37411
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03301
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46082
GSE210580_5_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.842056
behcet syndrome	GAD Gene-Disease Associations	1.0	null
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.207458
PMC10333092-aging-15-204811-s004.xlsx-Sheet1-Supplementary_Table_3_SP100_family_and_its_400_co-expressed_genes_SP100	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44204
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19892
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7478-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16316
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38927
KP-1N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_signficantly_upregulated_313_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.992571
EP300_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukopenia	GWASdb SNP-Disease Associations	1.0	0.379443
Kidney Chromophobe_KICH_TCGA-KN-8424-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01508
risk	GeneRIF Biological Term Annotations	1.0	null
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04442
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36934
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25136
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60716
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42148
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43265
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7167
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71355
DMS273	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864718
Sexual Dysfunction, Physiological	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93365
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50076
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41831
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896287
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49991
Thymus-myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.129535
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8171
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ERICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91864
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08324
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6387
RL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054124
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44116
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.37645
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82833
Common variable immunodeficiency 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.329984
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.43375
urinary bladder	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34575
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58093
RAD21	ChEA Transcription Factor Targets	1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15158
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71449
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Androgen insensitivity syndrome_Fibroblast_GSE3871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.40429
nb4	HPA Cell Line Gene Expression Profiles	1.0	0.850819
Perturb_1130_KO_Myc_SRP168941	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57876
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06099
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8174
Perturb_5816_OE_Erg_SRP239807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.7066
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL1-OVERLAP_GENES_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14325
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28982
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07797
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15804
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8872
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87513
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86825
decreased hematocrit	IMPC Knockout Mouse Phenotypes	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78248
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04744
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.877
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33734
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88737
SW1990	DepMap CRISPR Gene Dependency	1.0	3.37664
SRF	ENCODE Transcription Factor Targets	1.0	null
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16747
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
Human - Fetal Development - L1 - Antigen presenting cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
MBNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91583
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_6654_KO_Kdm4a/Kdm4b/Kdm4c_SRP190031	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67416
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211963_0_v_3_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05295
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53268
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08955
Lung adenocarcinoma_LUAD_TCGA-69-7973-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX2-sequence_name_MSX2	Rummagene Transcription Factor Associations 2026	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832802
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69326
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02174
PMC7462863-41467_2020_18186_MOESM13_ESM.xlsx-Suppl_Data_11-Supplementary_Data_11_Driver_genes_NOT_found_in_the_Mongolian_cohort_compared_with_previous_HCC_studies_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations	1.0	0.661873
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WSUDLCL2	CCLE Cell Line Gene Expression Profiles	1.0	1.67976
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.50796
EGR1	JASPAR Predicted Transcription Factor Targets	1.0	null
Parasubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09942
Cytosolic proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.19
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03425
Inflammation	CTD Gene-Disease Associations	1.0	1.25525
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24416
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WD40-repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06405
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03567
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.209776
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56702
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944547
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
Entorhinal area, medial part, dorsal zone, layer 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0876
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.199966
GSE186483_2_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	5.50408
superficial stratum of PaS (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47004
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38918
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1483
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83032
Liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31153
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1534
GRANTA-519	COSMIC Cell Line Gene Mutation Profiles	1.0	null
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.25905
REC1	CCLE Cell Line Gene Expression Profiles	1.0	2.21573
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83054
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08711
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32257
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86809
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24931
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72995
rectum	HPA Tissue Protein Expression Profiles	1.0	1.99325
OV90	DepMap CRISPR Gene Dependency	1.0	2.94225
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.86106
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59436
ZFHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91433
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
layer 2 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09108
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09116
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19313
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.995283
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39571
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12498
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968809
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLP8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68031
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29857
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL-745A cl. DS19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26405
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60386
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84324
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877131
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BT-549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13466
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3765
IGROV1	DepMap CRISPR Gene Dependency	1.0	3.6625
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22443
KELLY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848534
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.442367
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9117
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62163
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.979259
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11074_KO_Prkcb_SRP330448	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.98519
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24807
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02559
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890643
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25527
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28221
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3993
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31055
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980218
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987309
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.264567
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20058
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24932
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961149
reduced bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.407869
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCIXC	DepMap CRISPR Gene Dependency	1.0	5.18559
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11954
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NP8	DepMap CRISPR Gene Dependency	1.0	4.12915
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211931_1_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3057
Chromosome 16p12.2-p11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
hsa-miR-376a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07103
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.828542
NCI-H596	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_spleen-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87513
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
GSE122509,GSE122513_2_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Monocyte_Spleen_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.998698
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49619
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.85339
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899866
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833069
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828156
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02344
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2198
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
antidepressant type abuse	GWASdb SNP-Disease Associations	1.0	1.28906
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1086
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23283
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80407
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27114
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878731
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944933
daudi	HPA Cell Line Gene Expression Profiles	1.0	1.42055
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27196
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49479
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052537
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878854
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.307397
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85863
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09279
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03755
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838321
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919535
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1105
atherosclerosis	GWASdb SNP-Disease Associations	1.0	1.16261
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37572
TOV112D	DepMap CRISPR Gene Dependency	1.0	2.39883
hsa-miR-148b	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.86579
abnormality of limbs	GWASdb SNP-Phenotype Associations	1.0	0.166798
hsa-miR-4670-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
LAN2	DepMap CRISPR Gene Dependency	1.0	3.24267
KP-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-7271-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826373
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YH13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52046
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3459
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15359
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45878
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958441
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38412
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871913
abnormality of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.16127
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.149931
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64496
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.365551
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.213809
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935279
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57012
abnormal leukocyte count	GWASdb SNP-Phenotype Associations	1.0	0.382642
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70684
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82313
OCUBM	DepMap CRISPR Gene Dependency	1.0	4.35253
systemic	GeneRIF Biological Term Annotations	1.0	null
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05843
CCF-STTG1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885952
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1583
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.36234
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24018
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	14.5848
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8533
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68273
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.26992
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14457
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.550134
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Child Development Deviations	DisGeNET Gene-Disease Associations	1.0	null
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.867399
BL587 (FEN1)	NURSA Protein Complexes	1.0	null
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46864
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.233738
AHR-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2605_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.2926
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08224
Perturb_4376_KD_CREBBP_SRP072506	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.3457
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00042
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.69466
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.944938
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936782
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
35 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6734
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-AIRE-HIT_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913028
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04816
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
hsa-miR-938	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.19507
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834098
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6479
SYNCRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	2.19065
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06764
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88509
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bladder cancer	GAD Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7614775-EMS178742-supplement-Proteomics_Table_2.pdf-29-PRDM10_PRDM10	Rummagene Transcription Factor Associations 2026	1.0	null
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	1.62097
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96823
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79138
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864237
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57959
TBP	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-301a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Antisynthetase syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87027
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13877
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
variants	GeneRIF Biological Term Annotations	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03064
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.69088
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
YUHOIN0650	DepMap CRISPR Gene Dependency	1.0	2.16039
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.25676
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	6.90501
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36938
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80199
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828709
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.989
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13726
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09106
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00231
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14789
glucose	GAD Gene-Disease Associations	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33786
PMC3214047-pone.0027384.s003.xlsx-nr_listofpeakinhuman-TableS2_List_of_direct_IRF8_targets_in_human_GC_B_cell_lines_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947684
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.971622
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970916
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17159
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.128859
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12679
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84218
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36677
IKZF1	ENCODE Transcription Factor Targets	1.0	null
GSE135334,GSE136010_2_v_3_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5638
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.93802
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56738
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26602
EGR1	ENCODE Transcription Factor Targets	1.0	null
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05681
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.49368
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1222
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44535
HCC2157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integrin alphav-beta8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.053
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15713
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10369
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28289
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09044
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43109
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63267
MEG01	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57361
spleen	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
cholesterol	GAD Gene-Disease Associations	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42082
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.98717
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956953
agranulocytosis	GWASdb SNP-Disease Associations	1.0	0.731217
SNU-387	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCW-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31537
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02266
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11197
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71827
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4733-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12824
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37956
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98274
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.95917
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955912
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26229
PMC8045971-Table_3.xlsx-vs_LPS_ctrl-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867859
UACC893	DepMap CRISPR Gene Dependency	1.0	4.88656
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.894
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10771
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92553
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intrinsic component of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98646
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13439
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.826866
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.637318
decreased erythrocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901795
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834464
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	1.0	1.00367
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22305
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91824
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	1.40141
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86828
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86935
PMC7786291-Table_1.xlsx-Table_S1-Supplementary_table_1_ETV7-related_genes_in_the_TCGA_SKCM_data_set_ETV7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940774
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11637
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.6207
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Human - Lung v2 (HLCA) - L4 - DC1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41952
STAT3	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95781
ELF1	ENCODE Transcription Factor Targets	1.0	null
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50084
PCBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22196
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mental depression	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
Integral component of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
abnormality of cardiac morphology	GWASdb SNP-Phenotype Associations	1.0	0.637318
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_5_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.526896
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90352
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00689
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09436
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67417
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5132
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.73561
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4317
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912711
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4196
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137914_4_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24922
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874934
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69589
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
D-502MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25758
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7118_KO_Prkcd/Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.80391
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22063
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12688
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050069
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86333
ion binding	GO Molecular Function Annotations 2015	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22427
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06974
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	2.10844
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	3.11266
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59436
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855584
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.743226
Hippocampal formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29677
Perturb_13440_KD_MLLAF9_SRP119047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
neutropenia	GWASdb SNP-Disease Associations	1.0	0.731217
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4061
SYK_druginhibition_281_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.02684
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84561
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12306
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83771
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15503
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_4_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852671
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842053
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.785
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88135
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EHEB	CCLE Cell Line Gene Expression Profiles	1.0	1.38805
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09667
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913878
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Urinary Bladder Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16915
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12439
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24616
Sarcoma_SARC_TCGA-DX-A1L1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
MECOM	ChEA Transcription Factor Targets	1.0	null
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	3.70585
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14017
arteriosclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30061
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921741
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19754
NCIH684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56026
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.46485
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38643
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985522
Perturb_13649_OE_miR27_SRP067253	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.22178
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.13776
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892918
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41144
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4752
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.916097
THP1	DepMap CRISPR Gene Dependency	1.0	2.14247
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5616
GSE196540,GSE196542_4_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
SKNMC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56028
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37113
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82033
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00665
peripheral vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JJN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76289
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881008
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15503
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7866-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06292
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75428
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25912
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cSARS Bat SRBD_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.96936
GSE152637_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29087
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69046
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26285
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921547
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052585
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911439
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8489726-pbio.3001394.s016.xlsx-A-ZEB1_occupancy_plot-gene_symbol_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	1.22577
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5711528__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21316
bone remodeling disease	GWASdb SNP-Disease Associations	1.0	0.421487
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HS939T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63308
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996618
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.953853
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4942_OE_MLL1_SRP190074	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.28322
SMC3	ENCODE Transcription Factor Targets	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21684
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17424
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74467
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77075
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3869
HT3	DepMap CRISPR Gene Dependency	1.0	3.25686
NCIH1975	DepMap CRISPR Gene Dependency	1.0	5.42783
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863116
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BEACH domain	InterPro Predicted Protein Domain Annotations	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884802
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07079
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE101239_3_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01561
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10697
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01687
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04722
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12628
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.254664
Perturb_10730_KO_Nr1h4_SRP299252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53312
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868273
CI1	CCLE Cell Line Gene Expression Profiles	1.0	2.1667
CORL105	DepMap CRISPR Gene Dependency	1.0	2.41011
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11926
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907772
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14274
PMC11093744-41592_2024_2172_MOESM3_ESM.xlsx-ELP-genes_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931198
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19353
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79558
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
Perturb_10770_KO_Jnk1/Jnk2_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55417
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23414
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920155
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55187
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87988
USF1	ENCODE Transcription Factor Targets	1.0	null
artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.003208
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875406
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
single-organism process	GO Biological Process Annotations 2015	1.0	null
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26857
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54599
TASK1	DepMap CRISPR Gene Dependency	1.0	2.97508
Perturb_3813_KO_Cftr_SRP067491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	1.0	1.43572
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1975	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5526
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876109
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43686
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47254
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hepatic granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.737679
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1413
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.971622
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3461
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11296
PMC11629504-12864_2024_11077_MOESM1_ESM.pdf-2-ZHX1_ZHX1	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
CDX2	ChEA Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14031
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825423
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0339
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908654
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67347
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8942
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16237
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956934
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
hsa-miR-130a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0876
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
arthritis	GWASdb SNP-Disease Associations	1.0	0.398392
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
PMC3432194__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26396
VMRC-MELG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	1.0	1.38325
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
A2780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25595
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27232
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4022
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81195
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18115
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09745
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07687
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867604
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24453
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal bone structure	GWASdb SNP-Phenotype Associations	1.0	0.16127
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human - Fetal Development - L2 - Thymus-Antigen presenting cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
systemic lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48924
hsa-miR-148a	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10847
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839207
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34361
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.679898
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33605
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.232464
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68716
GSE116299_6_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUV39H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85478
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5146
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UGCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82489
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08071
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12106
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04165
Perturb_12558_OE_Aire_SRP033579	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33986
Poisoning	CTD Gene-Disease Associations	1.0	1.03864
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49619
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11026
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982482
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866716
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.22388
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05358
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83254
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.7649
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96371
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61908
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859471
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.04631
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11625982-AJH-100-10-s001.pdf-9-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.974608
GSE148692,GSE148695_5_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896108
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35005
19139136-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_13676_KO_Tcf7_SRP096347	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.659
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00689
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11282
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931033
Perturb_1220_KO_Klf16/Maz/Sp1/Zbtb7a_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0807
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13128
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74301
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86515
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77812
Autism	DisGeNET Gene-Disease Associations	1.0	null
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8047323-Table_1.xlsx-FC_LPS_T24_Vs_LPS_T0_P_0_05_FC-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34147
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50135
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06733
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_2_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism intracellular transport	GO Biological Process Annotations 2015	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12983
Brain Lower Grade Glioma_LGG_TCGA-DU-7015-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959697
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19946
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17769
heart disease	GWASdb SNP-Disease Associations	1.0	0.738443
Aorta	dbGAP Gene-Trait Associations	1.0	0.464073
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1282
KS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7142
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899401
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.225892
membrane part	GO Cellular Component Annotations 2015	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.64457
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27983
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11711
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8754
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919943
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26779
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15261
ZCCHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21933
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15106
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03402
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.60678
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1114
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76759
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9908
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9776
GSE139540_3_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06841
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.08592
ICC2	DepMap CRISPR Gene Dependency	1.0	5.09574
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54537
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8526
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.85251
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-80-5608-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1321
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983318
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42148
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843149
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72357
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838276
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.40157
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34589
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856499
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.305586
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47201
PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72716
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.313
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33142
ZNF623	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54483
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4769
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23398
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969536
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.97021
ARNT	ChEA Transcription Factor Targets	1.0	null
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850833
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-301b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1695
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36886
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62552
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.18113
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04744
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05386
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96371
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.481
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4659-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5735_KD_NAP1L3_SRP121475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.74428
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.92516
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AHR-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RPMI7951	CCLE Cell Line Gene CNV Profiles	1.0	3.00928
MTA3	ENCODE Transcription Factor Targets	1.0	null
blood	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946241
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842014
RL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6236
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4272
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.486425
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66246
RUNX1_01_159	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58966
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57754
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135359_0_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833689
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82509
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27972
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69802
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48327
EW-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34919
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93622
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1192
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07823
A498	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.776
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51616
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spleen	HPA Tissue Gene Expression Profiles	1.0	0.99943
UPCISCC111	DepMap CRISPR Gene Dependency	1.0	2.31256
ZNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79497
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.17876
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7711
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2822
NUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.60659
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95535
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830657
mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59948
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
HCC4006	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56321
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839392
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.050144
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5487
MDA-MB-157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875701
REST	ENCODE Transcription Factor Targets	1.0	null
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
DU145	DepMap CRISPR Gene Dependency	1.0	6.46627
behcet's disease	GWASdb SNP-Disease Associations	1.0	0.842929
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73938
Armadillo-type fold	InterPro Predicted Protein Domain Annotations	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952882
disease	GWASdb SNP-Disease Associations	1.0	0.118778
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17689
KASUMI6	CCLE Cell Line Gene CNV Profiles	1.0	1.33256
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
osteoporosis	GWASdb SNP-Phenotype Associations	1.0	0.407869
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01571
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05373
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14418
TP53	ChEA Transcription Factor Targets	1.0	null
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62429
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835195
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839755
abnormality of the upper limb	GWASdb SNP-Phenotype Associations	1.0	0.246934
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.80929
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
superficial stratum of PrS (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59436
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
decreased hematocrit	MGI Mouse Phenotype Associations 2023	1.0	null
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837367
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59509
Perturb_14516_KO_Kras_SRP311976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.62783
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.413
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872921
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994293
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96371
GTEx Brain 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	-1.0	-3.60707
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03692
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75557
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	2.95357
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95731
OE33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54057
PMC5731741__F4	PFOCR Pathway Figure Associations 2023	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.738443
PMC12370121-pone.0329101.s003.pdf-1-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23772
Response to anti-depressant treatment in major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
CDX2-19796622-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5192
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76304
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908849
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98992
wdfy4	GeneRIF Biological Term Annotations	1.0	null
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78785
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7391-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04566
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24906
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.313723
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49177
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05997
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86873
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2527
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46232
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03181
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967349
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dermatomyositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81902
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65193
lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85744
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29976
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901431
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22186
HS695T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06058
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3182	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17969
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02239
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10122
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875817
u937	HPA Cell Line Gene Expression Profiles	1.0	1.06464
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880288
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52263
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1194_KO_Klf16/Maz/Sp1/Zbtb7a_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1254
PMC7680901-Table_6.xlsx-both_up_GSE117165-SETBP1_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3414_OE_Zeb2_SRP072845	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65867
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16438
EP300	ENCODE Transcription Factor Targets	1.0	null
Blood-memory b cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0723167
hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44514
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.929827
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-0.982426
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850429
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10368
10q11 21q11 23 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977077
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111102,GSE111105_1_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ELF1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53015
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22174
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12370121-pone.0329101.s003.pdf-1-IRF4_1_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
ML-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36337
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06216
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5556-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2111
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35446
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1086
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053801
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40012
Perturb_2916_KD_FOXO1_SRP192099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.2265
Perturb_6216_KO_Mef2c_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.22591
Perturb_12094_KD_Cdkn2a_SRP169507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53504
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87964
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HS683	DepMap CRISPR Gene Dependency	1.0	3.93711
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57571
Perturb_1109_KO_Nkx2_SRP032537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.76516
Juvenile rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61087
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37363
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA42-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	2.03672
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84517
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38388
CALR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90694
mantle zone of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47004
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01197
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04816
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34549
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52002
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15219
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63621
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79108
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53138
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89596
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-551a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.217048
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.883267
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861739
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3165
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10697
hsa-miR-1470	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58776
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67154
PMC10350077-media-8.xlsx-PPM1D_tr_LPS_vs_Cont_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1611
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01257
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1282
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89505
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.063009
IRF8	ChEA Transcription Factor Targets	1.0	null
outer CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93978
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45356
USF2	ENCODE Transcription Factor Targets	1.0	null
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.82796
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11718
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1127
PBX3	ENCODE Transcription Factor Targets	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.944203
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57454
GSE120612_4_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.833
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53522
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02888
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12271
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9237
MYC	ENCODE Transcription Factor Targets	1.0	null
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07012
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866063
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075366
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
parasubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47004
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-21-VENTX_VENTX	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96371
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894557
GSE84678,GSE93902_1_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940042
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12993
studied	GeneRIF Biological Term Annotations	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07339
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29283
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-8121-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32432
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1490_KO_Rpl23a_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.98061
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82506
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86744
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1863
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07723
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980006
SW1463	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.03668
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866063
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42743
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85423
TM31	CCLE Cell Line Gene CNV Profiles	1.0	2.61868
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.131538
hsa-miR-146b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4580636-pone.0138782.s005.xls-Sheet1-Table_S3_List_of_Genes_with_RUNX1_binding_sites_in_each_Cytogenetic_Group_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.78895
TP63	ChEA Transcription Factor Targets	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30605
SNU1214	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02064
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11211
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44865
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21654
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70334
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09632
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	1.0	1.49446
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914221
Lymph_Node-cd141-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.362541
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19894
PMC4013678__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35279
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902186
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer 5 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14719
VCAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUL3	Pathway Commons Protein-Protein Interactions	1.0	null
lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03114
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8615-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
leukopenia	GWASdb SNP-Phenotype Associations	1.0	0.630475
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4390-01A-02R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.27615
Perturb_10928_OE_Mafg_SRP165896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.06935
Perturb_1709_KO_Tox_SRP054249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.5537
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050069
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88578
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72152
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053302
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05808
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T84	DepMap CRISPR Gene Dependency	1.0	2.00631
Perturb_11932_KO_STAG2/RUNX1_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.02539
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL_wt_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75102
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU449	CCLE Cell Line Gene CNV Profiles	1.0	1.6631
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.129
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12634441-41375_2025_2771_MOESM8_ESM.xlsx-ATACseq-Table_S3_Bulk_ATAC-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trans-Golgi network membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09911
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02887
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83884
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26843
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97637
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08612
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
STAT1	ENCODE Transcription Factor Targets	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9889
ES7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921529
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96343
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5386
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21454
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64663
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07305
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BL4237 (PPP2R1A)	NURSA Protein Complexes	1.0	null
GSE248858_6_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.589052
hsa-miR-1587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE126402_2_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8489726-pbio.3001394.s016.xlsx-B-ZEB1_peaks-ENSEMBL_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59447
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59121
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13314
Microglial cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60268
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3066
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996479
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC1B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55662
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7675
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09199
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08955
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rabies CVS-11_7day-Brain_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.98238
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49166
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23053
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.145
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33294
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88789
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38053
JHH6	CCLE Cell Line Gene CNV Profiles	1.0	2.04537
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986833
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
ASPC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49807
thp1	HPA Cell Line Gene Expression Profiles	1.0	0.925093
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24819
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909311
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-152	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
HUO9	DepMap CRISPR Gene Dependency	1.0	3.45128
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1282
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873947
abnormality of granulocytes	GWASdb SNP-Phenotype Associations	1.0	0.299346
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Paneth cell_Large intestine_Human	CellMarker Gene-Cell Type Associations	1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70152
NCIH1648	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25056
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04832
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.67873
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44223
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27477
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29173
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21865