association	dataset	threshold value	standardized value
KLE	CCLE Cell Line Gene Expression Profiles	1.0	3.3977
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7622
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907303
FOXI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41143
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44369
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69795
negative regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34697
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919029
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6442
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45395
HCT116	DepMap CRISPR Gene Dependency	1.0	4.7543
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38108
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61511
JMJD1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01058
Bronchoalveolar stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
hsa-miR-3667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_13723_KD_TP53_SRP162695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04383
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07288
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
Storage root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
LPIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49587
endopeptidase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80081
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.831997
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1096
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74739
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
CTCF	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60719
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63108
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53968
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0813
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64174
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34915
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	11.4122
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69173
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60567
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66214
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61181
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48074
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.62336
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74625
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64139
SSBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99245
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64534
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944031
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4389
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
CPT1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37841
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
cholesterol, ldl	GAD Gene-Disease Associations	1.0	null
hsa-miR-450b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08784
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04769
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Perturb_10434_KO_PPFIA1_SRP127326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97582
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34491
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SE-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25211
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32965
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24605
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
Perturb_11869_KO_Rb1_SRP062249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.62325
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21264
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	1.95579
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883993
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3152
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34099
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08678
CAL851	CCLE Cell Line Gene Expression Profiles	1.0	1.67534
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.690574
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29087
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
MFE280	DepMap CRISPR Gene Dependency	1.0	4.69915
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
Lung adenocarcinoma_LUAD_TCGA-05-4426-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73186
HCT15	DepMap CRISPR Gene Dependency	1.0	5.47541
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7512
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30477
BECKER	DepMap CRISPR Gene Dependency	1.0	3.75302
ARID5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6329
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05748
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82539
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4735
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91793
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89686
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4938
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33347
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3561
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8238
negative regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.8261
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14317_KD_PVT1_SRP341441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.87051
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58138
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6844
ARL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79443
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10259
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0249
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0349
H3K9ac_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45983
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56228
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9238
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8407
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.64791
LXF289	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85346
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26877
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63355
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
Perturb_12518_KD_TRA2B_SRP221583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.36171
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4696
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66439
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.987
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76667
hsa-miR-4736	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
peptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64608
GATA3	ENCODE Transcription Factor Targets	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20161
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69585
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTDNEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86074
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24819
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39217
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24747
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05374
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
CHL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85979
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26532
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857973
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28384
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51906
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80056
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Embryonic axis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8797
hsa-miR-219-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87918
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60037
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68716
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873887
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24997
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47266
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
enzyme inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853463
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9452
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58848
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22744
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836073
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52072
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7994-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70683
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07369
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72096
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.38987
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.301
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20534
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2609
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NP-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11386
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.4233
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7327
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84653
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23864
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4758
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18138
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47896
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48472
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17462
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64859
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.814
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
EWSR1	ChEA Transcription Factor Targets	1.0	null
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28258
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDARADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95107
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44314
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	126.07
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47325
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04447
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.306
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39556
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
Adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
ZNF678	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27478
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17048
ECC12	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18732
TGIF2LX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0459
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11022
peptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.425138
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
TBXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9205
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
HDAC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1341
Epididymis disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4807
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.91785
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33253
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76555
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
Lung adenocarcinoma_LUAD_TCGA-05-4427-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0542
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21357
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13405
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4838
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889146
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.081053
CORL279	DepMap CRISPR Gene Dependency	1.0	2.63043
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00997
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26882
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7783
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61427
NCIH1963	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46302
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991072
GSE238018_1_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23663
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02483
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97187
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847319
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49197
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46582
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.236324
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17918
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852165
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
496100546_TCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.41665
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
Tendril	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.946
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49637
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1536
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13599
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72992
chr20_45776018_C_T_b38	GTEx eQTL 2025	1.0	3.12422
Perturb_17308_KO_Pcgf6_SRP238553	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.6343
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25683
NO11	DepMap CRISPR Gene Dependency	1.0	2.36124
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8418-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93591
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.612
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31731
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14715
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95555
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.762
NUDT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70398
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183547
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42239
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
Cholesterol, LDL	dbGAP Gene-Trait Associations	1.0	0.616339
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30426
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71292
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.39061
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovarian sex-cord stromal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04497
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96343
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10008
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.3173
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10897
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899646
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94546
Lung squamous cell carcinoma_LUSC_TCGA-21-1078-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84645
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54086
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23222
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
RNF187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70543
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
Perturb_2635_KD_TRIM46_SRP323434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.6792
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999147
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3878
SP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08771
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00765
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.070903
Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851004
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52129
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49873
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.57554
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93947
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31508
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9688
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91848
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74122
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3018
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47356
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9041
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888229
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	1.5069
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7699
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18505
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A5RQ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87308
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
endopeptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32509
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.948047
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48749
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91026
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46559
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35884
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28461
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34922
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15948
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.286
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14085
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82962
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48566
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8101
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6089
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871099
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
EVSAT	DepMap CRISPR Gene Dependency	1.0	14.318
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87158
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83248
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11044
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.837
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.62774
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00905
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2643
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883993
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
external encapsulating structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.39471
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38324
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26111
negative regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931041
MRPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4796
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1659
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SQ1	CCLE Cell Line Gene Expression Profiles	1.0	1.5906
KON	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9253
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954015
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12451
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67382
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4481
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63628
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62188
SETSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0208
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00824
SRY	ChEA Transcription Factor Targets	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.699431
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WAP four-disulfide core domain protein 13	InterPro Predicted Protein Domain Annotations	1.0	null
BLOC1S4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33878
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18441
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03247
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028168
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
HS746T	CCLE Cell Line Gene Expression Profiles	1.0	2.17228
hsa-miR-3909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894489
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4351
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00714
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08133
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.465
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16897
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	1.33413
chr20_45783824_G_A_b38	GTEx eQTL 2025	1.0	1.40684
root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12084
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83307
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86378
KYSE-520	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
GSE186460_3_v_6_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64196
negative regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
Perturb_6408_KD_LINC00152_SRP134387	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.70353
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4069
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88274
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.963435
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5948
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26622
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.993331
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3576
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.83746
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89707
EW-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FKBP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8555
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85063
NAMALWA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0992
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
Apical bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82729
hsa-miR-3065-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160933
POU2F1-35413990-HUMAN-ARNEGCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.3741
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80192
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55311
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Lung adenocarcinoma_LUAD_TCGA-55-8090-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3289
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.3393
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78222
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207853_2_v_0_mafg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83768
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354084
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42689
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.46604
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43007
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBE2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62849
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06888
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27277
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7998
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00747
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37815
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46967
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31705
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.7705
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00765
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941678
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42248
TEN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72266
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881896
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33074
SNUC2A	CCLE Cell Line Gene Expression Profiles	1.0	1.44935
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15482
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	1.84895
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
defense response to bacterium	GO Biological Process Annotations 2025	1.0	null
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834268
LN18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62884
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38049
inner CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0067
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08601
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5812
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46219
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.186864
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9039
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33035
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99946
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61758
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
hsa-miR-4536	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08299
CORL311	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47385
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24496
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4259
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46234
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59642
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50311
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09168
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56949
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9754
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
negative regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45193
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986929
COX8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32703
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4769
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44312
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-215	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HGC27	CCLE Cell Line Gene Expression Profiles	1.0	2.01872
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
Epithelial ovarian cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43956
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13911
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15243
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79231
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4402
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5375
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.262432
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03696
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.212
negative regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54442
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0036
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.355
KU812	DepMap CRISPR Gene Dependency	1.0	2.1514
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-198	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.855135
PL4	DepMap CRISPR Gene Dependency	1.0	7.82161
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
bladder	GTEx Tissue Gene Expression Profiles	1.0	2.05875
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89022
shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30433
hsa-miR-769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24835
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	2.71349
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58553
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15426
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PROKR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72705
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69499
hsa-miR-4293	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985988
symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.32492
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09696
SCH	DepMap CRISPR Gene Dependency	1.0	3.25347
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15771
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
PTEN_01_301	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59408
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07819
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
AP1M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18684
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42729
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5598
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38987
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	75.3329
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37965
CMK115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55432
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69632
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6383
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56179
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3705
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3631
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
antibacterial humoral response	GO Biological Process Annotations 2023	1.0	null
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63719
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165758
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35442
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4446
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27793
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81461
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90708
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924557
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.54718
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01604
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0096
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
L3MBTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7246
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	2.2636
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1475
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73867
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69918
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18992
NCIH2405	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64525
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57153
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01725
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23163
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60405
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-374a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71516
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4402
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72127
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27507
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92089
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9681
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QK-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18876
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0464
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944845
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3321
apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38413
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15321
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07288
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841563
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71428
TE-8	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37911
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.688232
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3628
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96756
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29839
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05198
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68355
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14123
STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0758
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37911
SG231	DepMap CRISPR Gene Dependency	1.0	2.2477
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02729
SENP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65743
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.286019
496100387_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3507
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35425
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09104
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.62538
HMCB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83406
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.84628
KYSE70	CCLE Cell Line Gene Expression Profiles	1.0	1.91117
FAM110A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85716
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6464
antibacterial humoral response	GO Biological Process Annotations 2025	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74855
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042628
AKR1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24361
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27299
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28949
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62128
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34423
RRM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8246
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.878
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05683
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
Perturb_17291_OE_lncRNA5251_SRP239064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.41214
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864636
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14085
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39969
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71195
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7874
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49747
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.243167
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79144
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94642
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5563
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8126
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70311
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83802
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836073
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5158
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.40027
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923166
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64929
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05374
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944142
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65319
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17344
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41107
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34139
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853086
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9457
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
PMC4774101-13024_2016_87_MOESM3_ESM.xlsx-Table_S9-COMMON_DEGs_IN_AT_LEAST_3_OUT_OF_4_CONDITIONS_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827571
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90828
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12559
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
biological regulation	GO Biological Process Annotations 2015	1.0	null
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29079
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32484
SNU738	CCLE Cell Line Gene Expression Profiles	1.0	1.55017
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MG-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
ZKSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44244
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3696
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62083
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.378
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41647
NEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11093
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20979
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
HNT34	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30581
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37116
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56087
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44502
urinary bladder	HPA Tissue Gene Expression Profiles	1.0	0.841477
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48959
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ANKRD61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09969
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62507
PARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23991
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02205
IZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23443
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855676
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33994
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88033
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51182
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
hsa-miR-550a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7098
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37911
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3295
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36269
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33382
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858131
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29826
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57055
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14085
Perturb_2723_KD_HOTAIR_SRP172688	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.96462
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76787
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36612
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34311
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.91196
C2BBE1	CCLE Cell Line Gene CNV Profiles	1.0	1.57077
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78559
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924188
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25731
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1109
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63997
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55415
Perturb_18448_KD_PHF14_SRP199105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.80241
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50773
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2596
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39019
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883993
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63357
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00846
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49653
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.58108
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77317
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59968
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41587
SLC38A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3514
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873887
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9685
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56486
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1632
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.82785
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71838
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
HCC44	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35765
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
chr20_45756714_T_G_b38	GTEx eQTL 2025	1.0	1.218
HNRNPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45877
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74573
PRXL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5807
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0197
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12832
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5323
95T1000	DepMap CRISPR Gene Dependency	1.0	3.08559
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.11089
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79133
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97601
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02179
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55349
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45016
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14338
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.88547
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3578
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11554
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377621
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07527
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50411
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92001
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
hsa-miR-4283	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86595
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890208
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3753
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99782
PIAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78495
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	2.48328
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5156
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH7	CCLE Cell Line Gene Expression Profiles	1.0	1.50314
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918522
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.37233
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.605
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37263
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02899
Whey acidic protein-type  4-disulphide core	InterPro Predicted Protein Domain Annotations	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
CAAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32176
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54676
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6345
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5331
ZBTB33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66627
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97019
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54125
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96072
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82251
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49699
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51432
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41457
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10213
JEG3	DepMap CRISPR Gene Dependency	1.0	2.09508
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84215
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97026
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56995
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.44046
plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33139
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GS-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
HS766T	CCLE Cell Line Gene CNV Profiles	1.0	2.45002
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7760-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00416
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850008
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31681
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05374
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.473
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29215
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08832
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
Perturb_8987_KD_HNRNPM_SRP311345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.24422
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
SNU626	CCLE Cell Line Gene Expression Profiles	1.0	1.35734
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12415
PMC10859382-41392_2024_1740_MOESM3_ESM.pdf-39-NR1H3_NR1H3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.901
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47929
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68454
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995234
CHD1	ENCODE Transcription Factor Targets	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.79816
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341126
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19933
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18634
Perturb_17306_KD_Chrm3_SRP222274	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80397
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9209
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86952
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056153
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.108
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9784
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
KNS62	CCLE Cell Line Gene Expression Profiles	1.0	1.35717
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3085
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908685
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6195
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
PIK3CD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24736
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76759
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2516
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0295
A-CA-04-2009(H1N1)_0Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32319
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62997
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.43041
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0082
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66904
RSBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68709
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43096
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
ADAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93869
SET2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6814
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65606
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950716
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96659
biological_process	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47165
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63219
CAL29	CCLE Cell Line Gene CNV Profiles	1.0	1.89673
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21504
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4261
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25907
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80705
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X0-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50203
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
CDS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64375
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91616
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962124
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8787
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11452
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3737
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47663
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63959
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.27288
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74294
TMK1	DepMap CRISPR Gene Dependency	1.0	6.30386
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03632
LXF289	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38346
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50318
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
antimicrobial humoral response	GO Biological Process Annotations 2025	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06374
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5961
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75102
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-2.10001
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1477
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.795261
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20634
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67357
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85308
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34448
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20278
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986896
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.28
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03959
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602088
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859799
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58247
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3858
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69978
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
defense response to bacterium	GO Biological Process Annotations 2023	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1314
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27672
ISTMES2	CCLE Cell Line Gene Expression Profiles	1.0	1.49016
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89779
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7094
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67913
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.4243
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5332
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
KYM1	CCLE Cell Line Gene Expression Profiles	1.0	1.66229
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60114
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17975
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06374
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.96928
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A684-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5526_KO_Crtc1_SRP279598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3404
UACC893	DepMap CRISPR Gene Dependency	1.0	13.4313
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49168
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3003
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5491
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61639
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54866
HT-144	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99015
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929985
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52399
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.170315
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31696
GSE239844_11_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901379
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4891
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96618
MOLM6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84732
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4217
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66843
NKIRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79763
plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.48419
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34159
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34487
GSE212762_1_v_2_smarcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98701
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30587
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77792
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03819
CA46	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91338
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-3.21977
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.59571
Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889231
hsa-miR-4308	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RAB3IL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08385
GATA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18698
HS766T	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33686
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.37267
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323874
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48127
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0654
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
ARID4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80302
AR	ChEA Transcription Factor Targets	1.0	null
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.49063
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B2-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851004
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58189
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7156
MFE296	DepMap CRISPR Gene Dependency	1.0	2.60796
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
METTL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.162
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF768	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74425
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44734
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66371
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91072
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47365
CDKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33698
A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.20863
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1195
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58033
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93252
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27008
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10898
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31833
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5116
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22136
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.243167
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40047
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3537
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
Perturb_12517_KD_TRA2B_SRP221583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.04854
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18634
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51903
Lung adenocarcinoma_LUAD_TCGA-55-7911-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65209
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96876
RAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7047
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10693
ZNF217	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09047
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35121
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931529
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17808
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54647
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04244
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830792
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55915
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39217
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84531
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87571
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2712
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9631
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57874
negative regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
all	GWASdb SNP-Phenotype Associations	1.0	0.02815
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0214
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4800-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-4720-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07675
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11532
Perturb_15210_OE_MIR130A_SRP373399	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.11168
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82402
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.873552
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46843
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71801
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96307
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7732
HCC1187	DepMap CRISPR Gene Dependency	1.0	4.45251
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3483
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77217
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90997
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998309
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	2.21717
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30323
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9804
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1381
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80057
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83613
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65964
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907092
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87241
MDAMB157	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47579
ZBTB22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84917
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82067
HCC70	DepMap CRISPR Gene Dependency	1.0	5.4813
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.820365
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06438
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62875
hsa-miR-192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01887
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9194
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.81017
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68552
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
Perturb_15343_KD_PGR_SRP223388	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.05449
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.0
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91925
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-1251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040683
disease	GWASdb SNP-Disease Associations	1.0	0.023818
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1757
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11256
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.883
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.47459
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06338
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31473
OGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74179
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36282
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58277
SOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35665
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34875
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92439
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.484
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31696
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50737
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
antimicrobial humoral response	GO Biological Process Annotations 2023	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33335
HIF-2alpha_DEPLETION_GDS2760_643_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	2.43898
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00474
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8319
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944142
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10801
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875463
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854059
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2621
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26915
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE179002_3_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43601
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.98923
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	1.48017
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12508
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872556
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08711
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79385
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24804
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0123
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
SNU1041	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19732
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46458
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9425
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7033
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45324
SW1417	CCLE Cell Line Gene CNV Profiles	1.0	1.79967
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968434
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46811
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90822
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6148
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.525
MFSD6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05867
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
BCPAP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.37417
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44733
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955568
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07765
chr20_45793734_T_C_b38	GTEx eQTL 2025	1.0	1.5373
RKN	CCLE Cell Line Gene CNV Profiles	1.0	1.66145
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49752
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.044344
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41144
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.75275
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.469516
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8044
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844797
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68259
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86597
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05981
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0481
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856846
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51814
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130396_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.713
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12536
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MQ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361901
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1707
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27678
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36543
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.463
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.61565
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.962903
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905404
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	6.81536
ZNF791	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77529
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	1.46293
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06431
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.43964
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26743
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828672
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1611
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cdc42 GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1486
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47995
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36496
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8952
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
1321N1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.772
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21206
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Perturb_3741_KO_Gna13_ERP130529	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.2251
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24486
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81802
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.932
NKX2-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07778
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44084
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13461
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3PL-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825228
hsa-miR-3925-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hsa-miR-4782-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
A388	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12788
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17793
FNDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83312
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5277
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48554
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.40609
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83714
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.60641
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88013
MICAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76119
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81725
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4301
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04888
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860452
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.136138
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3027
Sarcoma_SARC_TCGA-DX-A3U9-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45236
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7278
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25749
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76513
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49596
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891848
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
Endometrial stromal nodule	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6404
hsa-miR-4515	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76784
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.626
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77928
GSE215086_0_v_1_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0813
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51651
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67664
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4486
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48938
endopeptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85557
Lung adenocarcinoma_LUAD_TCGA-69-7765-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6922
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.993331
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53897
TM9SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84777
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07037
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32838
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20448
MRE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95178
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97421
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65725
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875463
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DDX53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27041
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54233
SLR20	CCLE Cell Line Gene CNV Profiles	1.0	1.52036
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apical bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58338
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.14097
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30471
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550503
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98569
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50516
Epididymitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359292
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22377
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.550555
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19033
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832212
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898682
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900603
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49433
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33491
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.924623
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
COLO684	DepMap CRISPR Gene Dependency	1.0	2.71001
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6181
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24433
hsa-miR-4726-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
cellular_component	GO Cellular Component Annotations 2015	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63255
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92099
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98552
HUPT4	DepMap CRISPR Gene Dependency	1.0	3.98882
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04868
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06436
DDX56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.114
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	5.93079
WM793	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33267
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6730_KD_UPF1_SRP327782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.08969
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51791
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60421
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61654
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66129
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85523
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40929
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853394
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894624
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.737206
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
hsa-miR-4509	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
chr20_45774230_C_T_b38	GTEx eQTL 2025	1.0	1.57996
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32129
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95414
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15948
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29309
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3539
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10859
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955568
ID1_01_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.68403
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99852
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null