association	dataset	threshold value	standardized value
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06076
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEBL	Pathway Commons Protein-Protein Interactions	1.0	null
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.77025
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6109
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.61717
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59463
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.230521
AT 406	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13893
cell-cell junction organization	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828882
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.262869
PC14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55599
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43987
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858443
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01654
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
A673	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875177
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45185
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12997
artery disease	GWASdb SNP-Disease Associations	1.0	0.093969
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07713
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29225
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45216
MO-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86776
Myofibrillar myopathy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79069
define	GeneRIF Biological Term Annotations	1.0	null
RAD21	Pathway Commons Protein-Protein Interactions	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974099
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.735971
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61536
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gastroesophageal junction	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066498
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51304
hsa-miR-4716-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CMK	CCLE Cell Line Gene Expression Profiles	1.0	1.5749
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
heroin dependence	GAD Gene-Disease Associations	1.0	null
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41652
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1138
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872748
abnormal metabolism	MPO Gene-Phenotype Associations	1.0	null
mantle zone of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05415
HAL-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836681
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34031
ESS1	CCLE Cell Line Gene CNV Profiles	1.0	1.77129
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.305631
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.014
Bromfenac	DeepCoverMOA Drug Mechanisms of Action	1.0	0.63
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4482
GTEX-R55D-1526-SM-48FEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3204
abnormal heart electrocardiography waveform feature	MGI Mouse Phenotype Associations 2023	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912016
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21419
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
abnormal birth body size	MPO Gene-Phenotype Associations	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17486_KO_Otub2_SRP314435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.15692
Rectum adenocarcinoma_READ_TCGA-F5-6813-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01295
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11863
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12282
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958617
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03614
Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Diaphragmatic Hernia	DisGeNET Gene-Disease Associations	1.0	null
A1207	CCLE Cell Line Gene Expression Profiles	1.0	2.38465
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE114272_0_v_1_clk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00053
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0166
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bad5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
abnormal cardiovascular system physiology	MGI Mouse Phenotype Associations 2023	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33465
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1143
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897977
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5083
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61677
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.058128
Allergic contact dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
Congenital myasthenic syndrome 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.49697
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0864
Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.30239
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9810646-41598_2022_27273_MOESM1_ESM.docx-1-ZNF804B_ZNF804B	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61361
Lateral cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0673
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46021
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
abnormal apoptosis	MPO Gene-Phenotype Associations	1.0	null
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84817
Perturb_595_KO_Stxbp5l_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.1658
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.435775
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30852
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.711
CALU-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
focal adhesion	GO Cellular Component Annotations 2023	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094522
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20144
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0954
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21754
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3068
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94124
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
hsa-miR-4697-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31249
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07113
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5285
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2368
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.528
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8008
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.501476
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929997
GTEX-X5EB-1026-SM-46MVU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
L540	CCLE Cell Line Gene CNV Profiles	1.0	1.34668
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84995
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2536
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.72094
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.704225
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83577
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.313873
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26386
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.6212
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47835
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33141
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47256
chr2_167135776_T_C_b38	GTEx eQTL 2025	1.0	3.20917
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.049661
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22765
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31063
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.79088
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1	ChEA Transcription Factor Targets	1.0	null
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30918
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837881
PRKCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71201
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7994
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50569
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950348
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11423
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	2.79909
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal myocardial fiber morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76136
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6981
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894889
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.41716
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35234
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900286
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ETC-206_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0100618
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20616
Carprofen	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
cell-substrate junction	GO Cellular Component Annotations 2023	1.0	null
LRRK2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.879957
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85516
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11474
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6992
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886954
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929222
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17041
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85016
TE-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02378
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.38094
PMC5865663-oncotarget-09-14193-s002.docx-0-Supplementary_Table_S2_Somatic_mutation_Genes_which_are_high_frequency_in_TP53_signature_MT_TCGA_data_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TOV21G	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72847
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76555
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65285
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848197
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5542
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.04713
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954356
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10048
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.987442
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Semimembranosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7041
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28036
hsa-miR-1269b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE206870,GSE206872_3_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.38878
UDSCC2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80041
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3707
Autistic Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE157050,GSE157051_2_v_9_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02423
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6234
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48308
Perturb_9658_KD_SKIDA1_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.68922
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27835
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20782
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-X4XY-0326-SM-46MVZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53869
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5383
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1916
KG1	CCLE Cell Line Gene Expression Profiles	1.0	1.92045
dorsolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66275
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900896
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
hsa-miR-519d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal skin morphology	MPO Gene-Phenotype Associations	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.55535
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3467
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872748
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047561
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
increased cardiomyocyte apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
abnormal heart shape	MPO Gene-Phenotype Associations	1.0	null
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
myocardium hypoplasia	MPO Gene-Phenotype Associations	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35088
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863191
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
xirp2	GeneRIF Biological Term Annotations	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36336
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77721
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947295
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CALU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61377
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903215
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905017
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7939
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3174
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98833
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167125
WM-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7577
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919314
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72662
small liver	MPO Gene-Phenotype Associations	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAFB_02_11	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
ES6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHEMBL383736	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
intracellular part	GO Cellular Component Annotations 2015	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6696
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98487
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal hepatobiliary system morphology	MPO Gene-Phenotype Associations	1.0	null
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72187
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_6_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40477
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903215
pallor	MGI Mouse Phenotype Associations 2023	1.0	null
extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.301054
Apolipoprotein B mRNA editing enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33906
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865365
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.110594
KS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal cardiovascular system physiology	MPO Gene-Phenotype Associations	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1555
skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.3801
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.477
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LB771-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46013
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
Growth hormone receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-AS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
mitochondrial membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061363
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0888
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1502
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.81416
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19078
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3202
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03246
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16796
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913886
JZL 184	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97654
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
D-566MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8976
Perturb_13556_OE_Smyd3_SRP223218	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03517
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32235
CAL12T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92887
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17592
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19218
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62604
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ME-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
complete postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.15199
HS274T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64321
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91309
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65994
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55914
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33004
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30237
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08223
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32801
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57065
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181227
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.9889
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856692
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09297
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40338
contractile fiber part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.295119
Ibutamoren	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.22
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41612
Sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.886
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Lumenal side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64499
Perturb_8045_KD_ST18_SRP062868	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.66641
alpha-actinin binding	GO Molecular Function Annotations 2015	1.0	null
actin cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-16	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Perturb_7118_KO_Prkcd/Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.80729
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65389
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8564
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
BICR16	DepMap CRISPR Gene Dependency	1.0	2.37752
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_7129_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Heroin Dependence	HuGE Navigator Gene-Phenotype Associations	1.0	null
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.47584
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62472
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566428
Perturb_7078_KO_Ssbp1_SRP287547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.7316
skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.965928
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
REST	ChEA Transcription Factor Targets	1.0	null
A2780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04875
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5883
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
CANT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055753
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76081
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23598
Perturb_5711_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.94572
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.94401
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47698
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44774
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08087
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62036
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97422
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899479
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.168013
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3674
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
SRSF9_02_13	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03709
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954283
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13570_KD_Islr_SRP160431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSK343	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	3.99795
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18576
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46071
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.834818
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.761395
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Glycine cleavage complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.694
Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97073
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13117
RH41	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79611
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9545
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73941
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13174
PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
decreased heart weight	MPO Gene-Phenotype Associations	1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16156
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.45108
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
HLE	CCLE Cell Line Gene Expression Profiles	1.0	1.42759
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849589
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18342
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0018
CMK86	CCLE Cell Line Gene Expression Profiles	1.0	1.61513
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.36741
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_586_KO_Mtnr1b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.90053
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59064
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43418
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24522
Xin actin-binding repeat-containing protein 2	InterPro Predicted Protein Domain Annotations	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04588
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.17353
PMC4404138-pone.0124462.s003.xlsx-Sheet1-Genes_affected_in_the_MHC-CELF_severe_line_MHC-CELF_-10_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
Perturb_9657_KD_NKX25_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15671
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3577904-pone.0056590.s007.xls-Affected_genes-Table_S3_Significantly_affected_genes_in_MHC-CELF_hearts_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Myosin III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-182	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22726
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	4.6887
vincristine_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0131227
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10009
fallopian tube	HPA Tissue Gene Expression Profiles	-1.0	-0.845663
heart	GTEx Tissue Gene Expression Profiles	1.0	1.21322
enlarged myocardial fiber	MPO Gene-Phenotype Associations	1.0	null
MTMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79309
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4007
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37625
PMC10875160-mmc9.pdf-0-TP53_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7807
Perturb_2950_KD_Myog_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.62815
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04023
sc71	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
cell-substrate junction	GO Cellular Component Annotations 2025	1.0	null
GDM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AH-1026-SM-48TZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
UMUC16	DepMap CRISPR Gene Dependency	1.0	4.11503
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31307
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1341
regulation of actin filament organization	GO Biological Process Annotations 2025	1.0	null
Contractile fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.998
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00225
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68788
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86914
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998941
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28183
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TA-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68375
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12651
HDLM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.25825
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2435
FAM110A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21844
Sensory Perception	Reactome Pathways 2024	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43313
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49738
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56899
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77864
small myocardial fiber	MGI Mouse Phenotype Associations 2023	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.10388
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCBP1_02_137	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834603
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054262
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12961
GTEX-R55G-1126-SM-48FDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
postnatal growth retardation	MPO Gene-Phenotype Associations	1.0	null
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.046254
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autism	GAD Gene-Disease Associations	1.0	null
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37394
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12309
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9839
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87831
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44824
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4352712-NIHMS656781-supplement-1.pdf-12-ZNF567_ZNF567	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal heart size	MPO Gene-Phenotype Associations	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
SNU840	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37717
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16364
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32788
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.42645
z disc	GO Cellular Component Annotations 2015	1.0	null
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903215
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.13891
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85758
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12908
GTEX-PWOO-1026-SM-48TCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02826
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32123
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62938
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960695
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5056
ASPC1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.09642
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1817
abnormal ventricle myocardium morphology	MPO Gene-Phenotype Associations	1.0	null
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal myocardium compact layer morphology	MPO Gene-Phenotype Associations	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_15060_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.8742
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
SNU626	DepMap CRISPR Gene Dependency	1.0	3.05866
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNUC4	DepMap CRISPR Gene Dependency	1.0	7.88344
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.00959
17072341-Table2	GeneSigDB Published Gene Signatures	1.0	null
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26674
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3429
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45974
EPCAM_OE_GDS4887_343_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal heart weight	MPO Gene-Phenotype Associations	1.0	null
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.384
PMC5765157-41525_2017_40_MOESM2_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04983
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3098
cell-substrate adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.426711
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6971-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169697,GSE169725_1_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Contact dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4698
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16896
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15318
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13233
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.06213
CHP212	CCLE Cell Line Gene Expression Profiles	1.0	2.09682
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15624
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991114
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
Perturb_6353_KO_Smn_SRP253847	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.81235
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.696
abnormal heart shape	MGI Mouse Phenotype Associations 2023	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	2.99598
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11532
small myocardial fiber	MPO Gene-Phenotype Associations	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8832
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09043
GAMG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23543
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.338956
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20211
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9481
slow postnatal weight gain	MPO Gene-Phenotype Associations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gut microbiota (bacterial taxa, hurdle binary method)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
STAT1_02_23	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
NCI-H2030	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.686325
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39579
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27151
Perturb_3188_KO_Mrtfa/Mrtfb_SRP115705	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.72985
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82583
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02423
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55193
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51301
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2134
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20538
CTF1	MotifMap Predicted Transcription Factor Targets	1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36336
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Perturb_15620_KO_Net39_SRP273304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59026
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93689
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.987
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69765
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1102
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.041644
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNB75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
abnormal skin appearance	MPO Gene-Phenotype Associations	1.0	null
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24969
Perturb_11224_KO_Slc39a8_SRP308366	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC10805842-41531_2024_638_MOESM1_ESM.pdf-7-ARNT_ARNT	Rummagene Transcription Factor Associations 2026	1.0	null
inferior frontal gyrus, opercular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03099
SET2	DepMap CRISPR Gene Dependency	1.0	3.07754
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.886141
biological_process	GO Biological Process Annotations 2015	1.0	null
myocardial infarction	GWASdb SNP-Disease Associations	1.0	0.552202
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.14747
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-13_CD7_CD1a-_L-IC_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
a band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.336619
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
increased cardiomyocyte apoptosis	MPO Gene-Phenotype Associations	1.0	null
HSPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86257
Rupatadine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91925
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
8305C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KY821	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6955
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30268
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0826-SM-48TCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.42649
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15448
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857915
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
cell junction	GO Cellular Component Annotations 2015	1.0	null
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26635
POMGNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20884
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
JEG-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal liver morphology	MPO Gene-Phenotype Associations	1.0	null
contractile fiber	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ventricular myocardium compact layer hypoplasia	MGI Mouse Phenotype Associations 2023	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5026
Respiratory Function Tests	dbGAP Gene-Trait Associations	1.0	0.136297
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	15.5222
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3251
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09242
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75243
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46799
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74829
heart rate	GAD Gene-Disease Associations	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7974
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0669
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28416
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184087_0_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.149
Perturb_9759_KO_CTCF_SRP102228	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.46833
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00512
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92012
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840136
prostate	HPA Tissue Gene Expression Profiles	1.0	0.961978
IKKA	Kinase Library Serine Threonine Kinome Atlas	1.0	null
contractile fiber part	GO Cellular Component Annotations 2015	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.113317
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150444
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27691
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1223
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
OVCAR-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66589
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31615
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.00959
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897238
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04191
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2804
decreased liver weight	MGI Mouse Phenotype Associations 2023	1.0	null
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02856
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868966
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
TKKK	DepMap CRISPR Gene Dependency	1.0	4.29991
Perturb_16481_KO_IL6_SRP159090	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.3497
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
heart	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Zebularine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20403
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53483
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4707
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1143
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.861
small intestine	HPA Tissue Gene Expression Profiles	-1.0	-0.845663
SNU-449 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00179
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.84459
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased liver weight	MPO Gene-Phenotype Associations	1.0	null
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7847
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.729
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38912
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32486
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04758
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79005
Perturb_588_KO_Phpt1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.36398
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80054
NCI-H209	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal myocardial fiber morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06892
Bladder carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.313
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.481
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34321
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_585_KO_Lyplal1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30177
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20739
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920193
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20248
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.74856
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7635
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993052
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17066
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0928
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47017
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
Cardiac Arrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12764
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17004
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90278
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34827
KYSE410	DepMap CRISPR Gene Dependency	1.0	2.05417
C3A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.428
Vastus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99322
lateral orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06563
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85884
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-8.17002
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27042
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
BEN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76268
hsa-miR-106b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.00959
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65902
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901838
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28554
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04427
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
RL952	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77545
muscular ventricular septal defect	MPO Gene-Phenotype Associations	1.0	null
Trametinib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0134128
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO3-_-_vs_FOXO3_hMyotubes_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03844
SNU245	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87155
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
i band	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ventricular septum development	GO Biological Process Annotations 2015	1.0	null
PPP1R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62631
BICR31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827804
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4634
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19307
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30923
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Zofenopril	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
IRF1	ENCODE Transcription Factor Targets	1.0	null
myotube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37252
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05819
PMC7438927__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.077
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93218
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93812
hsa-miR-1269	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46693
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0546
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97952
increased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58026
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19745
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3W-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiac muscle tissue morphogenesis	GO Biological Process Annotations 2015	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972367
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Diabetic peripheral neuropathy in type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10969
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07281
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.79322
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38489
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047818
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26463
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
muscular ventricular septal defect	MGI Mouse Phenotype Associations 2023	1.0	null
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11448
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049748
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.00959
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal Purkinje fiber morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal heart ventricle morphology	MPO Gene-Phenotype Associations	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44598
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.851686
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17318
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37209
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45533
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12784
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.8132
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93736
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	0.820312
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.983688
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5588
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
SK-MG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057097
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842926
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9617
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
cellular process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92138
639V	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08117
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47866
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WZ811	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
Perturb_9525_Mut_Thra_SRP334033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.1598
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08628
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.39177
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KGN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13362
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8211
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03699
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9219
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09696
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55612
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
TCF4-18268006-LS174T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22942
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880087
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37114
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18955
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.295739
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.078633
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4442
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830703
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040705
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
prolonged QT interval	MGI Mouse Phenotype Associations 2023	1.0	null
Muscle myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1722
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53612
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867777
contractile fiber part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14318
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7446
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4478
appendix	HPA Tissue Gene Expression Profiles	-1.0	-0.845663
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33465
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2749
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF439	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56004
Xin actin-binding repeat-containing protein 1/2	InterPro Predicted Protein Domain Annotations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3241
bff3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13521
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Usher syndrome type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84532
NB1643	DepMap CRISPR Gene Dependency	1.0	2.07375
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03385
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62523
hsa-miR-374a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92719
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1004
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1233
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.40444
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14562
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12999
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86727
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965837
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852159
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0047
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35851
SK-MM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal response/metabolism to endogenous compounds	MPO Gene-Phenotype Associations	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85746
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34985
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14664
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striated muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09783
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02201
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43023
actin filament organization	GO Biological Process Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.882901
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.925005
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380251
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5047
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6395
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Fetal serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838951
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78265
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	2.81011
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02423
Muscle-slow muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	1.70438
Muscle-fast muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	4.40507
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
KMRC3	DepMap CRISPR Gene Dependency	1.0	2.29228
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09413
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54961
SEMA3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90969
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71419
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COR-L279	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.55325
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12777
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4925
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1249
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.723472
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.348725
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57926
cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal liver weight	MPO Gene-Phenotype Associations	1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.50472
Myofibrillar myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.102
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884508
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59349
Myosin XV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48439
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46074
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76882
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.955565
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1451
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4198
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.103352
heart	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HPAFII	DepMap CRISPR Gene Dependency	1.0	8.89065
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45145
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46817
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938126
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.487
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7677
SW403	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2049
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20739
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11437
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07956
ventricular septal defect	MPO Gene-Phenotype Associations	1.0	null
LS-123	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16866
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31471
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26602
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal liver size	MPO Gene-Phenotype Associations	1.0	null
Perturb_15618_KO_Mss51_SRP215371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46222
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.066236
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02545
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63889
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
Parasubthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03488
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_10616_KO_Ttn_SRP136441	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.55184
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60158
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.789
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55736
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9483_KO_Fnip1_SRP339469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.99808
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
osteochondrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.24776
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1251
cardiac hypertrophy	MGI Mouse Phenotype Associations 2023	1.0	null
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24532
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.53601
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6863-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atopic dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04774
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837259
tissue morphogenesis	GO Biological Process Annotations 2015	1.0	null
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9612
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.789545
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82788
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48194
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24086
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824119
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57565
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04225
GTEX-QDVN-1026-SM-48TZA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69481
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7664
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02044
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43595
Toll-like receptor 1-Toll-like receptor 2 protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29033
Striated muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15866
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11148097-41698_2024_569_MOESM2_ESM.pdf-213-ZNF277_ZNF277	Rummagene Transcription Factor Associations 2026	1.0	null
20502458-TableS6b	GeneSigDB Published Gene Signatures	1.0	null
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96753
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74985
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCI6A	DepMap CRISPR Gene Dependency	1.0	3.0839
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5214
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0098
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167886_3_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56115
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903215
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8258
CAPN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14902
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.505481
Anastrozole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
subthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07142
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58712
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37977
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982571
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53392
abnormal diastolic filling velocity	MPO Gene-Phenotype Associations	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	1.0	2.91893
PMC11625982-AJH-100-10-s001.pdf-100-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60866
Actin-binding, Xin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10039511-12864_2023_9238_MOESM1_ESM.xlsx-LPS_group-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	2.09609
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43685
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044824
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6725
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.11877
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07445
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1488
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
NCI-H2081	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923416
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.65
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07331
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894177
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.646
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
actinbinding	GeneRIF Biological Term Annotations	1.0	null
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490229
actinin binding	GO Molecular Function Annotations 2015	1.0	null
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44565
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38108
SCH	DepMap CRISPR Gene Dependency	1.0	2.45286
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00734
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.92993
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49821
MKN28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099509
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4687
MPT synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11346
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02636
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.20189
Perturb_17487_KO_Elavl1_SRP153419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.57052
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60622
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
SARS-CoV MA15_Day2-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.32896
TLX1::NFIC	MotifMap Predicted Transcription Factor Targets	1.0	null
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61228
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4760-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
abnormal heart right ventricle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE220	DepMap CRISPR Gene Dependency	1.0	3.00118
PMC9942321-12916_2023_2766_MOESM1_ESM.xlsx-S9-Supplementary_Table_9_DEGs_distributed_per_SOM_profile_in_all_IS_etiologies_based_on_Euclidean_distance_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Plasma renin activity levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.91822
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30909
actin binding	GO Molecular Function Annotations 2015	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54899
NCIH1623	CCLE Cell Line Gene CNV Profiles	1.0	1.44249
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17448
Perturb_7062_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.69815
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28282
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2046
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02494
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52382
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03925
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29029
KOSC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38763
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
NSMAF	Pathway Commons Protein-Protein Interactions	1.0	null
frontal operculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18446
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Perturb_12747_KO_Pten_SRP044242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.88189
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myocardial infarction	GWASdb SNP-Phenotype Associations	1.0	0.470969
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2667
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925915
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05055
Perturb_1336_OE_Zp407_SRP076817	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77957
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01147
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.658272
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38001
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13623
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78026
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6051
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52954
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17899
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29743
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89306
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32123
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03871
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOP-92	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19796
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6618
sarcomere	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MOGGCCM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38252
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13521
Geniculate group, dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3131
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7777
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38855
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39267
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8084
abnormal birth weight	MPO Gene-Phenotype Associations	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.099
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21398
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56104
HLF	CCLE Cell Line Gene Expression Profiles	1.0	1.3641
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
i band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.196669
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22551
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950692
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.8412
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
abnormal interventricular septum morphology	MPO Gene-Phenotype Associations	1.0	null
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892884
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9125
Perturb_6179_KO_Mecp2_SRP188207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.0737
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79234
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857613
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86164
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3L7-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950896
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6725
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06497
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44266
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54837
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58653
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13175
Acute Myeloid Leukemia_LAML_TCGA-AB-2865-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68408
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91638
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.33665
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69175
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3916	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10561
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01236
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181227
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949108
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.37223
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28023
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233548_1_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
small heart	MPO Gene-Phenotype Associations	1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.966
Extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
disorganized myocardium	MGI Mouse Phenotype Associations 2023	1.0	null
Hemochromatosis type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Lung adenocarcinoma_LUAD_TCGA-78-7542-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24095
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83103
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21696
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22125
BICR18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81414
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872797
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
abnormal myocardium layer morphology	MPO Gene-Phenotype Associations	1.0	null
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38108
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07775
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal myocardial trabeculae morphology	MPO Gene-Phenotype Associations	1.0	null
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906475
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.21899
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60708
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01966
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Myosin XVI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.299
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72106
Heart	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5022
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92711
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08686
enlarged myocardial fiber	MGI Mouse Phenotype Associations 2023	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7673
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.69283
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07474
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875629
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59175
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903215
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.295986
m band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.415728
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
Myofibrillar myopathy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.236
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58407
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45714
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4824
Perturb_10609_KO_Rbm20_SRP124759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1793
Perturb_6188_KO_Mecp2_SRP188207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.57443
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62936
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1341
KML1	DepMap CRISPR Gene Dependency	1.0	2.89629
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75574
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4495	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29589
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58048
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.93018
NP8	DepMap CRISPR Gene Dependency	1.0	2.35049
Perturb_16404_KO_Klhl41_SRP100902	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.02294
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68155
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32528
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.41378
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80465
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0108
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63285
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23241
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.307356
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08316
Mitochondrial electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995429
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.153
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7062-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased acetylcholinesterase activity	MGI Mouse Phenotype Associations 2023	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01763
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4436
cardiac hypertrophy	MPO Gene-Phenotype Associations	1.0	null
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40352
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98324
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7996
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8372
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52562
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3477
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.7151
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1365
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.605
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856025
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
GSE184087_0_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.75855
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50771
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55116
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
postnatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
hsa-miR-4670-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25083
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56761
ARID1B_01_298	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.81802
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01236
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83618
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469599
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61821
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08095
abnormal heart right ventricle morphology	MPO Gene-Phenotype Associations	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28711
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861216
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1962
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21274
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11394
GTEX-Q2AH-0926-SM-48TZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831033
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14526
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901031
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6614
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.487407
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051219
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48248
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19455
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0451
slow postnatal weight gain	MGI Mouse Phenotype Associations 2023	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876166
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04112
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
SH-4-54	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intermediate stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15277
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56924
DYRK1A	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905385
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23703
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75495
Perturb_6943_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal heart septum morphology	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3588
hsa-miR-4504	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46931
ARFGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.514
increased heart weight	MPO Gene-Phenotype Associations	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20318
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0533
TWSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05783
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4174
Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JIMT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0998
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10584_KO_Tbx5_SRP191501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5263
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20978
focal adhesion	GO Cellular Component Annotations 2025	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.17311
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2807
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9424
GTEX-QDVJ-0826-SM-48U1S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Atopic dermatitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.00959
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25597
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormal trabecula carnea morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_6940_KO_Rbm20_SRP403612	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.56178
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21757
A498	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18252
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30056
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915748
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03388
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
KALS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54571
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26594
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082319
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463013
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09704
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86256
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09626
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30128
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82678
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.984632
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46424
KCIMOH1	CCLE Cell Line Gene CNV Profiles	1.0	1.3589
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07968
KASUMI1	DepMap CRISPR Gene Dependency	1.0	3.42725
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5736_KD_Gdf10_SRP122537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.44616
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.307559
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1301
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1143
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858443
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3442
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995048
KYAE1	DepMap CRISPR Gene Dependency	1.0	2.64694
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856722
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841559
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832393
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21012
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.772199
SCC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32468
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3483
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	2.20396
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40663
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64631
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8902
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54885
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56498
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34356
NCIH2023	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07225
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
cisplatin_homo sapiens_gpl6480_gse33482	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040499
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38431
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9801
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83327
decreased diastolic filling velocity	MPO Gene-Phenotype Associations	1.0	null
diaphragm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.431843
MLLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35075
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.925613
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166643
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04221
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HPAF-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978072
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53997
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.581
parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.590437
NCI-H748	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12297_OE_TMEM33_SRP322205	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Actin filament bundle of actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894859
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73463
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988758
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S4-Supplemental_Table_S4_Differentially_expressed_genes_between_cases_with_G-CSF-induced_pY-STAT3_DMFI_1_5_STAT3_Low_v_DMFI_1_5_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25962
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2578
SNU423	CCLE Cell Line Gene Expression Profiles	1.0	1.55339
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05479
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
JVM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916487
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07995
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0157
synucleinopathy	GWASdb SNP-Disease Associations	1.0	0.868031
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18594
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17196
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.23846
Autism	DisGeNET Gene-Disease Associations	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92395
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4575
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5175
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30788
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2149
RD	DepMap CRISPR Gene Dependency	1.0	2.06867
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916487
abnormal heart left ventricle morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.487788
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.54883
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04324
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23241
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70014
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_10614_OE_Stk4_SRP121622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25569
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.722
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37236
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03086
MATH1	MotifMap Predicted Transcription Factor Targets	1.0	null
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3968
atrioventricular block	MGI Mouse Phenotype Associations 2023	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7876
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16373
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2208
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4668
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90641
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02719
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25221
cardiac septum development	GO Biological Process Annotations 2015	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4326
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68788
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47259
GSK429286A	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06903
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
M059K	DepMap CRISPR Gene Dependency	1.0	2.61158
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967558
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1284
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-519e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50454
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8758
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43531
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.068
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46969
ACCMESO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02336
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
PMC12211054-spectrum.00100-25-s0002.pdf-57-USF2_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18252
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0712
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.295986
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8761
myofibril	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856826
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48184
IKKB	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
MYO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05243
SAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894009
postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2339
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8706
HT115	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02043
GTEX-QDT8-2526-SM-48TYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60325
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3296722-pone.0032481.s009.xlsx-Sheet_1_MSC_vs_references-Gene_Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
z disc	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5547
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33465
LN235	DepMap CRISPR Gene Dependency	1.0	2.10945
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09165
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38175
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06902
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47275
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42825
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01504
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03035
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958438
Myofibrillar myopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
hypoactivity	MPO Gene-Phenotype Associations	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05175
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0195
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.417718
Gemmule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21838
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17899
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13806
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44545
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0969
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24522
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90428
mantle zone of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1068
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16219
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vemurafenib_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00738891
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.34501
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Myofibrillar Myopathy	DisGeNET Gene-Disease Associations	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60325
Cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.852
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95126
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46277
Perturb_3017_KD_Ttn_SRP222910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.35298
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880098
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19405
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69142
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Doxycycline (monohydrate)_AN3 CA	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0138562
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TF1	CCLE Cell Line Gene Expression Profiles	1.0	1.49384
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.65909
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	4.37904
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09069
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0783
GSE87404,GSE87812_2_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40955
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03614
myoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12613
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35086
hsa-miR-4761-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08668
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02919
SW1710	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72368
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32262
abnormal trabecula carnea morphology	MGI Mouse Phenotype Associations 2023	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.881802
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27668
liver/biliary system phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-Q734-0826-SM-48U1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1202
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectus femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
hsa-miR-17	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
YAMATO	DepMap CRISPR Gene Dependency	1.0	2.65224
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34582
K562	DepMap CRISPR Gene Dependency	1.0	2.156
myocardial infarction	GAD Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79556
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.26205
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
developmental process	GO Biological Process Annotations 2015	1.0	null
PMC3577904-pone.0056590.s008.xls-Comparison_to_SR_protein_KOs-Table_S4_Comparison_of_genes_affected_in_MHC-CELF_hearts_with_microarray_data_sets_from_cardiac-specific_SRSF1_and_SRSF2_knockout_models_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14759
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12791
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26758
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6527
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10606_KO_Abcc9_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51003
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850925
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04031
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17899
GSE239844_4_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76545
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99657
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ischemic bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.822897
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7412
abnormal intercalated disc morphology	MPO Gene-Phenotype Associations	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2645
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887342
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00495
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8278
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80084
plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.966793
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6147
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78477
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Perturb_6989_KO_Ptcd1_SRP120583	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.26215
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE101112_0_v_2_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
Perturb_575_KO_Abca8b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.18738
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29605
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00103
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01582
KPNYN	DepMap CRISPR Gene Dependency	1.0	3.29353
RAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24311
Perturb_13530_KO_Lbr_SRP012097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.41548
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32695
Perturb_11890_OE_Ddah1_SRP027595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.58032
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947512
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5ND-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_584_KO_Klhl8_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.02073
Myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.993
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sensory processing of sound by outer hair cells of the cochlea	Reactome Pathways 2024	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
regulation of actin cytoskeleton organization	GO Biological Process Annotations 2025	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.1334
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83952
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10188
muscle tissue morphogenesis	GO Biological Process Annotations 2015	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6729
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHEMBL200403	DeepCoverMOA Drug Mechanisms of Action	1.0	0.71
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25902
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29184
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57144
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39386
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	7.14665
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6495
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24703
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48867
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15016
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE135400_1_v_0_kdm1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67096
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43845
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54644
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.886
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061101
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15252
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myofibrillar myopathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
Perturb_9656_KD_MEF2C_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.9862
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17163
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92223
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54457
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39865
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45012
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11166884-mmc4.xlsx-Table_S3-Table_S3_proinflammatory-EC2_comparison_between_WT_and_TG_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.228333
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07703
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DYSF	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
A-172 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
TBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12233
t58-heart_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.35019
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.088109
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
increased apoptosis	MPO Gene-Phenotype Associations	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01184
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74749
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836304
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.8547
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13452
abnormal heart left ventricle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23726
Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23063
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39386
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.334
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954654
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855946
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47384
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867343
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74952
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91906
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80623
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69265
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19532
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60524
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94672
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21754
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19648
hsa-miR-20b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	2.04213
prolonged PR interval	MGI Mouse Phenotype Associations 2023	1.0	null
muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52961
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986158
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39586
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9982
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53867
Stereocilium shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.5732
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45563
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
A2780	CCLE Cell Line Gene Expression Profiles	1.0	2.11308
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE79696_0_v_1_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.00959
contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.219265
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11939
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24184
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13529
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.60459
abnormal heart morphology	MPO Gene-Phenotype Associations	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00008
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
hsa-miR-20a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07891
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937365
Muscle Damage	DisGeNET Gene-Phenotype Associations	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05774
Bladder urothelial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36033
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8657
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862006
disease	GWASdb SNP-Disease Associations	1.0	0.03148
PPARD	ChEA Transcription Factor Targets	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846717
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6398
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-595	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DOK	DepMap CRISPR Gene Dependency	1.0	2.23148
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.534251
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981813
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00834
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	1.35944
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3403
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.7545
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094552
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.4799
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35569
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0268
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3601
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11198
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21542
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.85645
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917692
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829842
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4124
Autosomal recessive nonsyndromic deafness 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
Rmz	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078178
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130401_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828375
HT1197	DepMap CRISPR Gene Dependency	1.0	5.14427
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27463
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17899
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2722
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6956_KO_Tefm_SRP114827	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44742
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3275
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5896
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993975
parkinson's disease	GWASdb SNP-Disease Associations	1.0	0.868031
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NCIH1437	DepMap CRISPR Gene Dependency	1.0	2.48521
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51013
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.955996
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17553
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73268
PNMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10369
WM1799	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67029
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.928849
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45933
rectum	HPA Tissue Gene Expression Profiles	-1.0	-0.845663
hsa-miR-515-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6476
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083816
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41523
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00272
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.278877
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02343
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S1_LMS_SNV-Supplementary_Data_1_Most_Recurrent_Non-Synonymous_Point_Mutations_in_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178403
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880932
Perturb_10615_OE|KO_Stk4|Lgals3_SRP121622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Sensory processing of sound by inner hair cells of the cochlea	Reactome Pathways 2024	1.0	null
BUB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17152
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.678
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65464
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28646
MM485	DepMap CRISPR Gene Dependency	1.0	2.20228
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3757
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931505
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45102
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8315-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06292
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02306
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.129
Heart Rate	dbGAP Gene-Trait Associations	1.0	0.188669
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93685
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3125	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890668
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02764
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.88032
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3675
CDK14	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12247
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65879
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06073
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93736
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59196
JHOM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42955
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC16A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20789
ECC4	DepMap CRISPR Gene Dependency	1.0	3.86378
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29424
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907623
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88218
Perturb_9799_OE_XPO4_SRP328169	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.13707
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2495
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23833
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65677
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04362
HDL cholesterol levels in HIV infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
Perturb_17778_KO_Creb_SRP178474	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31381
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59112
ES2	CCLE Cell Line Gene Expression Profiles	1.0	1.84979
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.50226
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.482467
extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280364
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.032941
Pepstatin A	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33465
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
respiratory function tests	GAD Gene-Disease Associations	1.0	null
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69154
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11342
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.621
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24447
KCL22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85962
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82414
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6627
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29852
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049196
HCC38	DepMap CRISPR Gene Dependency	1.0	3.53357
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4995-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transitional cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16753
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13409
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
hsa-miR-758	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82885
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
HCC1588	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84378
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64581
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NCIH3122	DepMap CRISPR Gene Dependency	1.0	2.27001
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
HMPOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.879561
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42169
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11695
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887537
hsa-miR-93	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
D-3263	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72111
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25164
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938613
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897116
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1757
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	2.26777
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86568
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.097
A253	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10621_OE_Mst1_SRP398098	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921724
LS-1034	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81028
Perturb_13461_KO_Pnpla2P_SRP261793	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.22117
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874779
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938537
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12520974-44161_2025_709_MOESM2_ESM.xlsx-Extended_Data_Fig_4a-Extended_Data_Fig_4a_Marker_genes_used_in_the_heatmap_for_ATF3_4_Capillary_and_Venous_in_non-ischemic_vs_PAD_comparison_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86406
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99755
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7776
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4358
supramolecular fiber organization	GO Biological Process Annotations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63557
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14708
PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932964
GLI2_01_143	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.72521
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3081
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
abnormal myocardial fiber physiology	MPO Gene-Phenotype Associations	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63386
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
LRRC75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52331
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31556
organelle organization	GO Biological Process Annotations 2015	1.0	null
GTEX-QCQG-0726-SM-48U1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29274
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08805
MED29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14179
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.206785
Perturb_17473_KD_Ubr4_SRP186572	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45829
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Parallel actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
NANOG	ChEA Transcription Factor Targets	1.0	null
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11498
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917245
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84795
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31364
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6794
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870739
EC-GI-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.77861
FOXP2	ChEA Transcription Factor Targets	1.0	null
abnormal muscle morphology	MPO Gene-Phenotype Associations	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-0.845663
Lumenal side of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862634
Fiddlehead	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24335
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99057
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43509
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56827
SKN3	DepMap CRISPR Gene Dependency	1.0	2.42277
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14181
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07449
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_3182_KO_Actn2_SRP218915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	5.78189
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60451
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49361
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03224
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0896
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85549
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8868
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SOX17	JASPAR Predicted Transcription Factor Targets	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8602
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69687
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70684
Thymus-fast muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	3.01736
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093265
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3347
20388125-TableS2	GeneSigDB Published Gene Signatures	1.0	null
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90976
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967276
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831984
hsa-miR-125a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41066
decreased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
PIP4P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47429
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37191
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22397
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53959
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1704
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0301
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29532
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39665
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59671
Congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5932
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17106
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF304	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74218
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11602
Sensory processing of sound	Reactome Pathways 2024	1.0	null
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
BRAF	Kinase Library Serine Threonine Kinome Atlas	1.0	null
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46153
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.19971
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
SCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.226331
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52083
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03212
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6483
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12913
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26512
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09612
CALU-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40338
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12834
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109935
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70966
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896806
abnormal impulse conducting system conduction	MGI Mouse Phenotype Associations 2023	1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0912
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5632
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841074
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090336
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06841
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58323
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03777
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851891
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876341
I band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.962
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34462
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03117
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10518
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9049
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2654
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19438
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4441
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
CMLT1	DepMap CRISPR Gene Dependency	1.0	5.13589
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15927
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56616
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37209
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33329
hsa-miR-624	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
KARPAS-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78798
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.376202
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959815
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41495
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.212
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01235
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22944
KYSE520	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32086
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3138_KO_Med1_SRP078070	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.82743
LI7	CCLE Cell Line Gene Expression Profiles	1.0	1.41533
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39699
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96252
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52748
xin	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37295
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6986
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
22RV1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76063
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06547
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22948
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44861
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
T-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE92364_0_v_4_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stereocilia tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
G70994MS	GlyGen Glycosylated Proteins	1.0	null
Autosomal dominant nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2182
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.341
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953491
MEG-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08392
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57978
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08196
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42847
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08223
BCKDK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09775
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4037
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal muscle physiology	MPO Gene-Phenotype Associations	1.0	null
NEB	Pathway Commons Protein-Protein Interactions	1.0	null
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54437
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	3.27177
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr2_167166767_G_A_b38	GTEx eQTL 2025	1.0	1.8227
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35851
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2019
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02719
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56055
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17309
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45226
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948684
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.078983
U-118-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9934
PMC4070589-NIHMS573166-supplement-1.pdf-15-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09986
NCI-H1915	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2868
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8106
Vas deferens ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
PMC10875160-mmc9.pdf-0-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
KNS-81-FD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal muscle fiber morphology	MPO Gene-Phenotype Associations	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944212
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5848
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
HS940-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Minocycline	DeepCoverMOA Drug Mechanisms of Action	1.0	0.54
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05902
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.206785
Perturb_6941_KO_Rbm20_SRP403612	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
MYC_OE_GSE43730_684_human_MCF10A cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03333
OE33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21969
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12789432-41467_2025_66251_MOESM4_ESM.csv--SOX2_tumorigenesis_signature_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
DTWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60289
EN	DepMap CRISPR Gene Dependency	1.0	4.05207
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9721
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05768
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40699
Peripheral nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.702
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69133
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4737
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43578
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02636
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Perturb_7124_KO_Prkcd/Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8161
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.81963
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68406
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32873
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00389
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960329
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04712
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055162
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00713
Perturb_2889_KO_Mcrip2_SRP302058	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.41298
Perturb_593_KO_Rbp4_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.49132
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal myocardial fiber currents	MGI Mouse Phenotype Associations 2023	1.0	null
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09807
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884607
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11097
HT55	DepMap CRISPR Gene Dependency	1.0	2.06992
Neuropathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.702
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12938
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.702
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86333
hsa-miR-106a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958791
U4/U6 x U5 tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17891
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85737
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2719
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.44689
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17434
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37897
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6395
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33447
abnormal atrioventricular bundle morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PMC4404138-pone.0124462.s002.xlsx-Sheet1-Genes_affected_in_the_MHC-CELF_mild_line_MHC-CELF_-574_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
contractile fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429072
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830147
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
decreased diastolic filling velocity	MGI Mouse Phenotype Associations 2023	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.264
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.42752
abnormal cell death	MPO Gene-Phenotype Associations	1.0	null
CHEMBL217125	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.56
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.2574
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr2_167193016_G_C_b38	GTEx eQTL 2025	1.0	2.85504
PMC12307501-Table1.xlsx-ST12-Supplementary_Table_12_Results_of_the_comparisons_of_AP_expression_levels_between_different_biological_age_groups_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22158
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46308
Caki-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81345
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.124
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49445
MDA-MB-468	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TULP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04558
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142629
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49413
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47008
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1802
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34224
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.68971
HNRNPK_02_136	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.70044
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5097
increased cell death	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47935
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72704
Upper tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.058
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.45473
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nuclear cyclin-dependent protein kinase holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.224
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G402	CCLE Cell Line Gene CNV Profiles	1.0	1.41282
abnormal intercalated disk morphology	MGI Mouse Phenotype Associations 2023	1.0	null
cell-cell contact zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14749
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.05286
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10492
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.691
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33615
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04827
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49646
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99879
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1213
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
decreased birth weight	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-X62O-0826-SM-46MW8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860654
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15016
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4576
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19307
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44419
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
JAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46492
PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860686
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	4.1829
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877076
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29315
ID1_01_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.5442
SNU8	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
HDQ-P1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal cardiomyocyte apoptosis	MPO Gene-Phenotype Associations	1.0	null
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	3.40816
abnormal blood circulation	MPO Gene-Phenotype Associations	1.0	null
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.544006
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40143
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4956
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.923319
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096616
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37723
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54585
blood vessel wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874434
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25087
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37898
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3196
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35965
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16125
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31599
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
all	GWASdb SNP-Phenotype Associations	1.0	0.036191
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15811
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32473
PMC11625982-AJH-100-10-s001.pdf-9-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5919
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48356
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1575
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917692
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87068
Bay 60-7550	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.29426
NRF1	ENCODE Transcription Factor Targets	1.0	null
TMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75865
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01244
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6216
RETREG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62404
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BHT101	CCLE Cell Line Gene Expression Profiles	1.0	1.52244
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.95
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081497
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytoskeleton in muscle cells	KEGG Pathways 2026	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41381
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
peduncular paraventricular area of PHyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05415
GSE213632_1_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7699
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.19616
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5903-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2267 (TDP1)	NURSA Protein Complexes	1.0	null
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889832
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59771
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ventricular myocardium compact layer hypoplasia	MPO Gene-Phenotype Associations	1.0	null
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46724
fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.668436
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6294
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.453
GSE152055_2_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CJ-42794	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4085
GSE153923_1_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09066
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
decreased body size	MPO Gene-Phenotype Associations	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVOL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8435
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45868
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8056
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040588
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.873172
PMC6065369-41467_2018_5367_MOESM9_ESM.xlsx-Table_6-Correlation_analysis_between_expression_of_ESR1_and_actin_regulators_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57965
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05624
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.818
GTEX-Q734-1426-SM-48TZQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01681
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18126
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1351
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3091
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30443
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41751
YD10B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59414
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34289
PMC7438927__F7	PFOCR Pathway Figure Associations 2023	1.0	null
NCI-H460	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25064
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal heart layer morphology	MPO Gene-Phenotype Associations	1.0	null
Sartorius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39772
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911844
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 70	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5108
PMC10709143-41556_2023_1271_MOESM7_ESM.xls-PAX7_Re-injury-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.307004
PMC11609822-cd-24-0018_supplementary_table_s8_suppst8.xlsx-Visium_Clusters_DEGs_LR_test_LF-gene_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.78803
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77753
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
Perturb_7066_KO_Lrpprc_SRP110979	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.13839
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26391
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18913
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915502
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54857
SB-222200	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
TGBC24TKB	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
enlarged heart	MPO Gene-Phenotype Associations	1.0	null
decreased birth body size	MPO Gene-Phenotype Associations	1.0	null
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18543
motif	GeneRIF Biological Term Annotations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4428
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2528
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9416
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1233
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.00959
Perturb_9659_KD_SOX11_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.3291
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42009
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12075
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55192
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03205
vascular disease	GWASdb SNP-Disease Associations	1.0	0.067269
Perturb_7040_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.70036
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
KCIMOH1	CCLE Cell Line Gene Expression Profiles	1.0	1.6353
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4658
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54593
GTEX-TMMY-2226-SM-4DXTN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11394
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54175
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7144
GSE195559_3_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4907
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
LB647-SCLC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9660_KD_ZFPM2_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94152
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20661
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78488
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1276
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1	CCLE Cell Line Gene Expression Profiles	1.0	1.68339
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50174
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GS-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	2.9722
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31973
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8813
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.83445
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03835
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2558
Bexarotene	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.165
catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.474018
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06763
abnormal interventricular septum muscular part morphology	MPO Gene-Phenotype Associations	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4638
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSK1059615_SNU-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0127954
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4363
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MAFK	ENCODE Transcription Factor Targets	1.0	null
GRK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912894
decreased birth weight	MPO Gene-Phenotype Associations	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_OE_GDS4763_332_human_MCF10A - immortalized breast epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09165
Ets	MotifMap Predicted Transcription Factor Targets	1.0	null
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65612
satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456828
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19512
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
UT7	CCLE Cell Line Gene Expression Profiles	1.0	1.70382
Autosomal recessive nonsyndromic deafness 27	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.031
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.4548
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
HCC2814	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37028
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1225
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35161
Rucinol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
insulin resistance	GWASdb SNP-Phenotype Associations	1.0	0.528492
Fast twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.22638
NUP205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59674
JHU-011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299601
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34184
Osteochondrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
Integral component of lumenal side of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09066
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.227
Macitentan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
MOLM16	CCLE Cell Line Gene Expression Profiles	1.0	1.47966
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43153
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22367
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07647
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55264
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090336
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35811
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85325
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3219
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48031
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40567
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5067
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0886
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05847
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31436
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.12774
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.93679
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Unnamed_1_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
ST486	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98025
C-4-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21225
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94931
HCC2108	CCLE Cell Line Gene Expression Profiles	1.0	2.21492
GSE112358,GSE112359_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50183
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
disorganized myocardium	MPO Gene-Phenotype Associations	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.22215
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
LS411N	DepMap CRISPR Gene Dependency	1.0	3.89702
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.761395
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40529
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13875
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Perturb_1030_KO_Apoe/Apoa1_SRP318735	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.50876
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92235
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
peduncular subparaventricular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1068
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16248
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59987
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QCQG-1526-SM-48U25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
Perturb_15865_KD_LSD1_SRP228812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.69917
Perturb_13531_KO_Lmna_SRP012097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.17164
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
Perturb_16400_KO_Pak1_SRP351351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50592
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PAK6	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59505
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2179
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06093
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927247
Lung squamous cell carcinoma_LUSC_TCGA-98-8023-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
KRT4	Pathway Commons Protein-Protein Interactions	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.127
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56357
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80352
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47449
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	2.60036
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.00959
GSE183890_7_v_10_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180951_2_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060687
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.016
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.948239
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7328
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
Microvillar actin bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
Z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.986
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00752
Mucosal melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15397
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61027
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14708
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.624
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.63365
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77398
SNU-423	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_6944_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3477
Congenital diaphragmatic hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58348
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26356
nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.345078
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67106
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.262869
abnormal cardiac muscle tissue morphology	MPO Gene-Phenotype Associations	1.0	null
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47053
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06647
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880741
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.53183
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40373
NB12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal postnatal growth	MPO Gene-Phenotype Associations	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.488549
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51208
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21539
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
AN3CA	CCLE Cell Line Gene Expression Profiles	1.0	1.95498
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853964
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23017
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7253
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
actin filament-based process	GO Biological Process Annotations 2015	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16298
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05823
actin filament organization	GO Biological Process Annotations 2023	1.0	null
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62064
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	4.72275
TCF4	ChEA Transcription Factor Targets	1.0	null
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4685
IGROV1	DepMap CRISPR Gene Dependency	1.0	4.75798
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Lung adenocarcinoma_LUAD_TCGA-44-7661-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49569
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99015
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rotigotine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.711
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2016
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50743
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36329
pallor	MPO Gene-Phenotype Associations	1.0	null
GTEX-SUCS-1126-SM-4DM61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.40998
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.252
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Pinometostat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
Perturb_17466_KO_Prm7_SRP067359	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.36205
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57021
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.761395
cell junction organization	GO Biological Process Annotations 2015	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4606
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1869	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FLNC	Pathway Commons Protein-Protein Interactions	1.0	null
EM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59059
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myocardial Infarction	dbGAP Gene-Trait Associations	1.0	0.012667
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1556
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051146
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45426
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
regulation of supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0355
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56498
hsa-miR-145	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43213
RD	CCLE Cell Line Gene Expression Profiles	1.0	1.79973
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29114
postnatal growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
SW1990	DepMap CRISPR Gene Dependency	1.0	4.12856
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	1.64732
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874671
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608527
PMC11609822-cd-24-0018_supplementary_table_s8_suppst8.xlsx-Visium_Clusters_DEGs_LR_test_LF-Unnamed_0_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	5.77915
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02423
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54938
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventricle myocardium hypoplasia	MPO Gene-Phenotype Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertrophic Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39662
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09328
RD	CCLE Cell Line Gene CNV Profiles	1.0	2.0754
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BICR22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.163641
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959069
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57998
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85043
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81863
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33069
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34933
abnormal response/metabolism to endogenous compounds	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82712
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-14_CD7_CD1a-_L-IC_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
HUCCT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55023
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24779
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70379
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15468
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.45092
Diaphragm disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Perturb_17753_KO_Nae1_SRP407900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7353
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
Skeletal muscle myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.629