association	dataset	threshold value	standardized value
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06064
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16943
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56784
CHD1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52785
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
RAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17238
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42919
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47282
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13373
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993251
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981356
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12814
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69322
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947525
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924432
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8651
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042429
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95262
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64447
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.837
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29081
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64014
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97883
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2762
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05139
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61443
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	2.13011
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46709
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09584
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.33156
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05431
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07387
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
CBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053738
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02021
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40561
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9523
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
NACAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85549
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90451
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28462
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
Cytoskeletal organization and intracellular transport regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
CA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-1.12482
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40676
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-01A-31R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17819
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47289
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87907
Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65874
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Thoracic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990083
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25098
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0186
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84426
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053703
PCGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48334
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2795-01A-02R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998585
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1141
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77984
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.939913
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7953
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85888
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7746
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	2.19077
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922378
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33452
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2336
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29663
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81151
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40561
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99311
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46298
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13796
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2075
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4033
zar2	GeneRIF Biological Term Annotations	1.0	null
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18125
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.37147
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	1.61942
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13918
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947007
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60826
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IM9	DepMap CRISPR Gene Dependency	1.0	2.72671
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X3-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
BT-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67732
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.35716
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13154
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.6576
Transcription factor TFIIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
Sarcoma_SARC_TCGA-KF-A41W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Distal arthrogryposis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7224
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55386
Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1645
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9132
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45875
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8994
PLA2G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94368
Ovarian cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6593-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48634
peptide biosynthetic process	GO Biological Process Annotations 2023	1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5626
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02034
Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30624
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.981487
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29061
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969273
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38693
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83546
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.294
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41306
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.18072
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3401
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16253
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94978
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31552
PUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83635
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.3336
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13647
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37059
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16309
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414673
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23158
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.37198
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
OSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13754
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7878
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75065
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55434
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44797
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87096
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68392
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92785
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876628
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13972
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05014
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51535
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0041
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
MYC	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H508	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67255
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21569
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7028
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83714
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42279
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57907
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4097
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48981
ZNF384	ENCODE Transcription Factor Targets	1.0	null
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887626
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12623
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.68693
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04397
TRAFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4646
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.137
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33462
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26942
expressing	GeneRIF Biological Term Annotations	1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.981
SOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5664
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70972
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850371
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44624
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.99338
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95296
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65535
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01284
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31669
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1966
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7144
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20674
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.25103
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5921
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10623
PRKAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07362
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80213
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36633
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89016
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.94035
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48267
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32525
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56915
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485935
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4742
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01909
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34595
Lung adenocarcinoma_LUAD_TCGA-44-3396-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08389
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981356
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1966
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23234
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62874
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95184
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12688
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07952
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12847
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02051
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64327
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100345_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12445
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11693
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39741
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04719
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26598
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44267
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66389
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
COQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27846
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9319
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35791
CARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6871
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.577
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
c4type	GeneRIF Biological Term Annotations	1.0	null
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
u698	HPA Cell Line Gene Expression Profiles	1.0	0.956281
VAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07787
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	3.92923
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36561
ZNF829	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42624
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56336
OVSAHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83728
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43142
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1755
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64845
SEC31B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49317
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38828
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5792
B4GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83391
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60362
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04383
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0535
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17446
FBXO38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10898
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7819
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91999
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22177
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72331
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40425
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17328
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16316
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824047
SW1116	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81436
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.16791
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00088
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988093
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68735
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51969
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04903
ACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32837
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24088
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56232
Fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2375
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56509
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61246
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.20348
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94138
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1232
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6059
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01968
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51208
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74585
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.63278
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06263
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-common-common_genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_HL-60_and_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9618
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3403
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6843
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08967
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25042
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1605
PMVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92211
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
negative regulation of protein metabolic process	GO Biological Process Annotations 2023	1.0	null
hsa-miR-885-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4493
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79057
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94904
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00095
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12959
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852059
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10317
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21924
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7194
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988921
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49276
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
ZC3H11A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7468-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.942645
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
DIFI	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39922
NACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63014
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20406
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14777
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23197
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87625
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83838
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04634
skin	GTEx Tissue Gene Expression Profiles	1.0	1.23376
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833175
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53356
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46382
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JADE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95961
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86239
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05532
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46036
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74461
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.611
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32767
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.882051
OC314	DepMap CRISPR Gene Dependency	1.0	12.1899
CDCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24614
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84243
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8768
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74503
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20835
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082643
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35425
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861928
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03626
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85741
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.1184
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18305
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043041
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20543
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transcription	GeneRIF Biological Term Annotations	1.0	null
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD2_02_33	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.76553
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11949
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78699
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20466
KP2	CCLE Cell Line Gene CNV Profiles	1.0	1.33676
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00538
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.4277
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.888623
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27615
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
CMK115	DepMap CRISPR Gene Dependency	1.0	3.65911
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75577
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05972
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81461
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39244
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77508
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50925
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36695
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44003
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0685
JTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84568
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.678
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48578
LS513	CCLE Cell Line Gene CNV Profiles	1.0	1.52556
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney	HPA Tissue Protein Expression Profiles	1.0	0.985348
KP3	DepMap CRISPR Gene Dependency	1.0	2.07916
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32146
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852059
POLR2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14048
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01459
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47274
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89169
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.6517
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45931
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1747
BRCA1-C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
SRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19564
regulation of translation	GO Biological Process Annotations 2025	1.0	null
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06386
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65725
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
SLC25A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67744
nucleolus-like body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902063
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53579
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35865
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90445
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11773
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62374
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07091
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50818
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48474
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16145
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079041
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24072
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
RCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87317
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041792
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06895
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61453
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1682
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59643
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37568
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGFG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0789
SP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26502
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73045
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61474
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13547
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21798
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.68693
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55167
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
RB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40629
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.27184
Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48206
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44295
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.99019
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49785
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53814
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91101
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893896
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55628
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843181
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
GAMG	DepMap CRISPR Gene Dependency	1.0	2.68224
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-1.86918
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27043
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40564
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20698
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29323
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36672
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62887
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48574
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.81308
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947007
translation	GO Biological Process Annotations 2023	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gene expression	GO Biological Process Annotations 2023	1.0	null
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4684-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
AOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04487
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9278
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06149
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92793
Nuclear speckles	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5389
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38809
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF534	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83856
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6019
G402	DepMap CRISPR Gene Dependency	1.0	4.9634
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.57263
KCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49919
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3076
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77117
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38978
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3119
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21621
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041465
SNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40475
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2158
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53232
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78429
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0707
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	4.43791
Lung adenocarcinoma_LUAD_TCGA-97-8176-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8277
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55893
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871165
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67013
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
NUDT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65701
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59955
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.493354
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63526
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.88
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08694
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43109
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82766
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19082
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.088
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
BARX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06207
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06369
DXO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60378
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84944
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54547
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89008
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1329
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22942
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0589
Nuclear cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
TC205	DepMap CRISPR Gene Dependency	1.0	2.06532
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	1.0	1.0528
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.478
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.87631
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89805
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03907
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53014
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912691
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626273
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92845
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988092
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892474
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24847
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.33453
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83838
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
mRNA binding	GO Molecular Function Annotations 2025	1.0	null
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HeLa-S3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
CHMP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5238
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6689
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78493
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3532
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03347
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8759
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852059
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932803
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91231
GSE253113_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22957
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.774568
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055427
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3473
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39904
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26181
ZNF844	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56213
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0601
negative regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29949
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7929
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89271
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62098
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1968
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23236
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078146
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947007
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3326-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07817
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.91563
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983719
NPrEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995415
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PM-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90855
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64262
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66068
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endometrioid ovary carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
NCI-H748	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.306
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888721
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76304
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.56135
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391553
SEC16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97598
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44015
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.0834
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76395
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5625
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10227
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97303
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
HEY	DepMap CRISPR Gene Dependency	1.0	2.81539
SHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18303
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70744
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931576
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16783
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20841
NMB	DepMap CRISPR Gene Dependency	1.0	2.15735
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4439
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7474
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84351
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59693
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05406
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.461
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6095
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.106
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90057
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9965
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00079
SUV39H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78883
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16078
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0619
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5468
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63808
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78238
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079889
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17477
negative regulation of translation	GO Biological Process Annotations 2025	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29768
NCO2	DepMap CRISPR Gene Dependency	1.0	2.31903
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17388
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24591
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06616
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825698
FUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86563
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18353
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7836-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
cytoplasmic mrna processing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.680284
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12228
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9702
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42982
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33663
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3778-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.846
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2286
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	1.37086
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20841
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14153
OE33	CCLE Cell Line Gene CNV Profiles	1.0	1.41185
PRPF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49453
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02817
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51169
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7732
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03443
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17583
SDHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82418
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15254
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64546
Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ES4	DepMap CRISPR Gene Dependency	1.0	2.15656
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38731
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.9166
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862736
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
KREMEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25335
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8973
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02776
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7711
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.88
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52145
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898673
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33983
Prostate adenocarcinoma_PRAD_TCGA-FC-7961-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80149
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11217
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77881
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16556
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.99019
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86587
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.75107
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.31919
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74984
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	2.41906
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.903163
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24541
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02044
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94016
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98209
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47445
ETS1	ENCODE Transcription Factor Targets	1.0	null
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
STX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.333
USF2	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94138
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2715
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
CNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77791
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	-1.0	-0.774568
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61872
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89057
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03153
Breast carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.477
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12491
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21239
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.08521
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of cellular biosynthetic process	GO Biological Process Annotations 2023	1.0	null
CLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98641
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18711
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5116-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9199
ORMDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99664
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38803
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.2571
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98147
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22435
ICC2	DepMap CRISPR Gene Dependency	1.0	5.65186
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5868
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25933
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57331
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39403
BRAF_drug inhibition_GSE42872_368_human_A375	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_02_192	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888721
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42318
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856116
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64977
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59395
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03434
Thoracic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
MM485	DepMap CRISPR Gene Dependency	1.0	3.36895
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845476
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.447
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38419
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84631
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7495
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
ANAPC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07755
PCDHGC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49595
SKNMC	DepMap CRISPR Gene Dependency	1.0	4.43449
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01968
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59128
chr13_32311074_GT_G_b38	GTEx eQTL 2025	1.0	2.17573
TMEM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11062
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7428
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66683
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-7	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.579
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78416
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925183
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831653
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55349
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5851
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1071
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.72081
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.73105
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91298
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.611
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145161
FYCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98122
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1487
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77805
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RBM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53357
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29178
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989891
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
brca2	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04634
MEGF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
negative regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2023	1.0	null
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01735
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5855
MTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39876
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825172
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31585
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853861
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19111
superior parietal lobule, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09954
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMEM198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32236
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94589
SP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909838
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35855
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05983
CWR22-Rv1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57665
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9532
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56923
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3546
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13693
VPREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25791
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894061
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28787
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81116
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843649
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88292
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56334
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60842
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43065
TE9	CCLE Cell Line Gene CNV Profiles	1.0	1.78262
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13444
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83299
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25223
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05634
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34182
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23843
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17553
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02015
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.00426
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6858
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0321
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43836
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951373
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96706
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2403
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5983
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88507
ZFP69B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79546
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63233
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854531
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2716
PLXNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.674
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65219
hsa-miR-4755-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18441
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18491
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03475
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39145
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900795
MAP3K9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62736
hsa-miR-615-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
abnormal female meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30706
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86746
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.943505
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6557
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83838
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551695
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U2OS	DepMap CRISPR Gene Dependency	1.0	2.16633
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of translation	GO Biological Process Annotations 2023	1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47234
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37929
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.942414
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51395
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49097
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.774568
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96946
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1954
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mullerian aplasia and hyperandrogenism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45327
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
HILPDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39002
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49057
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8059
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3081
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53882
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5071
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25092
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0888
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92531
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87566
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89846
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16316
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62805
translation	GO Biological Process Annotations 2025	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2238
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69952
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.15183
RUNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61041
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.082
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6001
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.14914
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.55559
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48283
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.958306
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900795
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
ZNF816	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22715
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.954818
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17744
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05181
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49361
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14833
containing	GeneRIF Biological Term Annotations	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825172
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
zinc	GeneRIF Biological Term Annotations	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85935
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM1799	DepMap CRISPR Gene Dependency	1.0	2.64007
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950555
ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.559285
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7999
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
BACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6649
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2716
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8887
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20408
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
C8orf33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53003
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13495
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054036
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.68693
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39249
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.985874
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
promoter	GeneRIF Biological Term Annotations	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6846
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11101
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN3_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91114
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981356
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15034
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.537
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47499
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7445
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58127
Ovary adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW948	CCLE Cell Line Gene CNV Profiles	1.0	2.28623
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95405
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73972
MCM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2945
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8044
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1463	CCLE Cell Line Gene CNV Profiles	1.0	1.46296
Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100291_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54663
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98424
Lung small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.867
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.6565
CAOV4	DepMap CRISPR Gene Dependency	1.0	5.66353
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26743
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
finger	GeneRIF Biological Term Annotations	1.0	null
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05381
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31629
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90953
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	6.0194
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69066
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139540_4_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67625
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81679
CWC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61678
Ovarian carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08422
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60628
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28151
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89684
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
Fetal alcohol syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24605
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71699
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86576
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5578
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50243
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5074
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28345
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10623
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4641-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98042
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21523
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
TFAP2C	ChEA Transcription Factor Targets	1.0	null
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863205
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851208
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8096
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37661
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.858416
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21161
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6775-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5304
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76912
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3902
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.99019
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2336
gene expression	GO Biological Process Annotations 2025	1.0	null
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81855
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8428
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00329
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82294
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42299
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825172
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KB-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98597
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48725
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1205
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82821
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.988449
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40586
chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.17671
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33929
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38809
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36221
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57291
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.888721
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
ADI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70991
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01938
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66505
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63381
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15872
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6153
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24934
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9933
Zinc-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Zygote arrest protein 1	InterPro Predicted Protein Domain Annotations	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947554
HSC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5368
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62084
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36678
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	2.26405
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60309
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55092
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.837
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27202
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.43107
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96897
Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01591
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908755
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28582
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FLO1	DepMap CRISPR Gene Dependency	1.0	2.07082
cytoplasmic ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.142837
RAD21	ENCODE Transcription Factor Targets	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.179
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30722
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15192
LRP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87587
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.21136
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23728
NB1643	DepMap CRISPR Gene Dependency	1.0	4.75398
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51668
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100446_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5586
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0936
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32131
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6692
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59064
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13599
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88073
estrogen-receptor negative breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15671
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13896
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39178
SKUT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66043
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16462
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851293
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63332
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1798
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
Distal arthrogryposis type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.1
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81716
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07132
negative regulation of amide metabolic process	GO Biological Process Annotations 2023	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54699
SMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08495
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4928
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.2229
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33046
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46996
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76667
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43479
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4346-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
mRNA 3'-UTR binding	GO Molecular Function Annotations 2025	1.0	null
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840544
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45092
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
Lung squamous cell carcinoma_LUSC_TCGA-85-8048-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20533
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09168
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.774568
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.387
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07369
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57714
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6651
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5263
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMK2	DepMap CRISPR Gene Dependency	1.0	2.30521
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9302
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64509
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.79722
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36032
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOU-NH91	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09946
COV434	DepMap CRISPR Gene Dependency	1.0	3.65435
regulation of translation	GO Biological Process Annotations 2023	1.0	null
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4804
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06338
DSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17428
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0936
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1853
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
End-stage kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64611
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
Ovarian disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92783
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97996
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.83323
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8615-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4533
mRNA 3'-UTR binding	GO Molecular Function Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7675
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15992
mRNA binding	GO Molecular Function Annotations 2023	1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40991
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0184
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5586
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18122
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02043
NB13	DepMap CRISPR Gene Dependency	1.0	9.93974
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21161
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26442
precentral gyrus, left, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830242
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28081
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4092
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.66622
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825172
Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.51868
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829236
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5621
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66302
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83024
Ovarian serous carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70207
cell part	GO Cellular Component Annotations 2015	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92922
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC35B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34995
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83224
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90579
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29717
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59124
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
FAM131A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73072
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	2.32895
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23608
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67912
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855079
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.96595
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09394
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gonadal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78938
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981356
Breast disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.57
LCLC103H	DepMap CRISPR Gene Dependency	1.0	4.06163
tb1lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.323
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02912
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.024
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43074
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76572
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.48435
HICS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19773
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98033
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71315
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889741
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93081
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19146
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95997
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NI-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H12D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28184
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48277
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32133
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HEC59	DepMap CRISPR Gene Dependency	1.0	2.07993
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.6983
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2026
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.999017
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.402
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42308
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17901
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35091
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57589
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89744
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88088
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
IL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08707
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29178
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35802
NB1	DepMap CRISPR Gene Dependency	1.0	2.53344
Lung adenocarcinoma_LUAD_TCGA-75-7031-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.73452
CHD2	ENCODE Transcription Factor Targets	1.0	null
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04213
intracellular part	GO Cellular Component Annotations 2015	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2284
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41955
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43868
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
ULBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64885
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.953934
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41318
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71692
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1525
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64663
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78893
ACAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21129
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66956
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Blastocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33368
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54625
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.978816
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2897
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16424
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55534
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932045
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04387
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07785
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00715
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49939
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45158
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51074
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02603
placenta	HPA Tissue Protein Expression Profiles	1.0	1.68693
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4899
bidirectional	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
HMC18	CCLE Cell Line Gene CNV Profiles	1.0	1.55374
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053704
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4523
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
negative regulation of protein metabolic process	GO Biological Process Annotations 2025	1.0	null
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12452
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
ARFGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99264
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2935
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
MEIOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14226
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7146
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.707
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73899
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47364
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45548
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
Ovary epithelial cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.411
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.774568
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26396
ASB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42224
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85512
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182