association dataset threshold value standardized value H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null malaria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.322637 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955922 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18135 POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32758 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32756 lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980003 H3K4me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null plasmodium falciparum malaria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.756564 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870941 NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular part LOCATE Curated Protein Localization Annotations 1.0 null HTC-C3 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08663 POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3121-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943378 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5479 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KYAE1 DepMap CRISPR Gene Dependency 1.0 3.25587 GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.939534 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75896 GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 cellular metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-Q2AI-1326-SM-2S1PL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21397 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07118 FTC-133 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68A-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC70 CCLE Cell Line Gene Expression Profiles -1.0 -1.56601 GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.9992 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.21438 respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040352 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.44874 mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.78893 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38641 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03079 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.940803 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL2 ENCODE Transcription Factor Targets 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.96568 CPCN CCLE Cell Line Gene CNV Profiles 1.0 1.80454 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.946911 cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 RMG-I COSMIC Cell Line Gene Mutation Profiles 1.0 null VTP-27999 DeepCoverMOA Drug Mechanisms of Action 1.0 0.28 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR8 CCLE Cell Line Gene CNV Profiles 1.0 1.46103 POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null perifornical nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0118 HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49836 TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.92572 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.998409 JUN ChEA Transcription Factor Targets 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS123 DepMap CRISPR Gene Dependency 1.0 5.212 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049963 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.953817 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982025 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HAT dimerisation domain, C-terminal InterPro Predicted Protein Domain Annotations 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null esr1_21713035_mcf7_lof_human_gpl570_gds4061 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.24742 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40188 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A718-01A-22R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of biosynthetic process GO Biological Process Annotations 2015 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89147 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29376 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857001 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.969973 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67173 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.445718 thalassemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.454093 Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57973 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.991638 lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921237 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06684 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GABPA_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084418 TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.29555 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4332 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle LOCATE Curated Protein Localization Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07762 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13686_KD_LDB1_SRP398635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GABPA_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63117 GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.918253 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.97592 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09161 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16408 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13457 GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.94435 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.81414 PCI6A DepMap CRISPR Gene Dependency 1.0 13.9409 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.48567 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.126037 SREBF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA ENCODE Transcription Factor Targets 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 organelle GO Cellular Component Annotations 2015 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.66439 MFE296 DepMap CRISPR Gene Dependency 1.0 5.30422 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854196 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.17216 H3K9me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6724_KD_PAF1_SRP103746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.53896 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.06407 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.65782 NR3C1 ENCODE Transcription Factor Targets 1.0 null GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.863852 MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-Q734-0226-SM-48U1A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.830792 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CBC2181 (NFRKB) NURSA Protein Complexes 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CBX3 ENCODE Transcription Factor Targets 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_10150_KO_FOXK2_SRP251223 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32472 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.26264 NCI-H2172 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.17015 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HT-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null KYO1 CCLE Cell Line Gene Expression Profiles 1.0 1.81434 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054089 SNUC1 DepMap CRISPR Gene Dependency 1.0 10.198 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10865 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null LXR-623 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.61 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.076855 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7613_KO_LARP1_SRP201361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HOS COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_13927_OE_ESRRG_SRP363188 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.0527 WERIRB1 DepMap CRISPR Gene Dependency 1.0 2.46221 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.73078 ATF3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01034 H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946781 Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SP2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SR786 CCLE Cell Line Gene Expression Profiles 1.0 1.41175 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.066266 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RP-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CL-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50686 H3K9me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880612 positive regulation of epithelial cell proliferation GO Biological Process Annotations 2023 1.0 null X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.874866 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854196 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900444 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.925583 POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null subiculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.929059 MDAMB468 CCLE Cell Line Gene CNV Profiles 1.0 1.38338 GABPA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adipose tissue GTEx Tissue Gene Expression Profiles -1.0 -0.83367 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK4_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5335 Perturb_7327_KO_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.99832 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.970677 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24442 BCLAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null UACC-893 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.2474 TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Lung adenocarcinoma_LUAD_TCGA-05-4249-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.17218 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01408 Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051795 Perturb_2528_KO_TET2_SRP163132 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.83701 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99267 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90492 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051796 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38623 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Integrase, catalytic core InterPro Predicted Protein Domain Annotations 1.0 null DNAJC2-21179169-NT2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-548f TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RVH-421 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.83949 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08113 nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085287 USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S32W-1226-SM-4AD67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.885291 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-0326-SM-3DB86 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01924 ventrolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34095 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.60238 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null TCF3 ENCODE Transcription Factor Targets 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCLAF1 ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.878942 GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.53395 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25884 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058174 GABPA_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SSA3-0226-SM-32QPN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18815 Vemurafenib DeepCoverMOA Drug Mechanisms of Action -1.0 -1.08 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.996409 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-1326-SM-46MUN GTEx Tissue Sample Gene Expression Profiles 1.0 0.851484 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.96918 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.920214 GTEX-UJHI-1626-SM-3DB9A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894879 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48174 increased red cell sickling tendency GWASdb SNP-Phenotype Associations 1.0 0.994551 KYSE150 CCLE Cell Line Gene Expression Profiles 1.0 1.38515 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null binding GO Molecular Function Annotations 2015 1.0 null hsa-miR-548x TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.15913 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.224545 u138mg HPA Cell Line Gene Expression Profiles -1.0 -0.894171 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TOV-21G COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.832533 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55891 H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null tardbp_19910924_hek293e_lof_human_gpl570_gds3730 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.251136 GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 1.08902 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.831701 GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935239 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69457 H4K20me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.919763 GTEX-XLM4-0008-SM-4AT4W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848729 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.71039 EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.68234 GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855507 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.15901 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15994_KD_MIAT_SRP221619 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.15258 Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79556 KYSE150 CCLE Cell Line Gene CNV Profiles 1.0 2.09674 Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.29095 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07139 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852625 basolateral nucleus (basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.98739 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 1.9968 Perturb_3517_KD_RBM8A_ERP130710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.0709 RD COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TML8-0526-SM-32QOQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.968351 H3K9me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881321 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 NCIH1299 CCLE Cell Line Gene CNV Profiles 1.0 1.65389 Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18592 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 647V CCLE Cell Line Gene CNV Profiles 1.0 1.4882 T98G COSMIC Cell Line Gene Mutation Profiles 1.0 null MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 0.867645 GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Perturb_7828_OE_ALYREF_SRP111407 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.927 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78905 Perturb_2546_KD_EZH2_SRP067706 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.23489 Perturb_7494_KD_DICER1_SRP186271 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.98149 granular layer of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835664 NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14295 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-0926-SM-2TF56 GTEx Tissue Sample Gene Expression Profiles 1.0 0.861584 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.90794 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.82407 POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WFG7-1826-SM-3GIL1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.993725 EBF1 ENCODE Transcription Factor Targets 1.0 null salivary gland HPA Tissue Protein Expression Profiles -1.0 -1.02635 Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938507 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965186 k562 HPA Cell Line Gene Expression Profiles 1.0 1.66297 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12815 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44466 PEA1 DepMap CRISPR Gene Dependency 1.0 3.64178 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.49606 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.987051 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05812 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 2.16721 nucleic acid metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_4876_KD_BANCR_SRP135857 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.98888 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.894772 GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12196 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neurodegenerative disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 Perturb_7571_KD_PRP5_SRP340978 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828439 ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA2 ENCODE Transcription Factor Targets 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3148 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 ETS1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRL-1626-SM-2YUMU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.858927 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spleen_3c HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood serum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.648938 hsa-miR-548e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00783 H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VMRCLCD DepMap CRISPR Gene Dependency 1.0 6.09972 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null spleen GTEx Tissue Gene Expression Profiles -1.0 -1.01566 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 all GWASdb SNP-Phenotype Associations 1.0 0.03873 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.61582 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.02762 bonemarrow_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.00129 NCI-H1963 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.265725 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COR-L321 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.71882 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17253 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.43176 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26767 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IM-95 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.69749 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31592 Perturb_7959_KD_ZFC3H1_SRP222099 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.80756 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4076-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.979664 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 1.307 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36254 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null 10min_PPase_inhibitors vs ctrl_Hepa1-6 (Mouse) [18846507] SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24C-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 E2F1 ChEA Transcription Factor Targets 1.0 null H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 0.946516 GTEX-NPJ8-0226-SM-48TBN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.858869 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860417 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.40147 primary motor cortex (area M1, area 4)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.840863 GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852625 LP1 CCLE Cell Line Gene Expression Profiles 1.0 1.71009 disease of mental health GWASdb SNP-Disease Associations 1.0 0.053477 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.86837 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16263 GABPA_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36272 Perturb_7558_Mut_ASXL1_SRP305063 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.06479 Perturb_10147_KO_FAM122A_SRP235545 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.45052 GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31767 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947499 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08458 Schizophrenia DisGeNET Gene-Disease Associations 1.0 null facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38436 H3K79me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null sickle cell anemia GWASdb SNP-Disease Associations 1.0 1.138 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34641 RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16587 Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of cell population proliferation GO Biological Process Annotations 2023 1.0 null DOK DepMap CRISPR Gene Dependency 1.0 2.02753 Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040659 GTEX-RWSA-0126-SM-2XCBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-XBED-1326-SM-4AT4F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839664 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CCC5 DepMap CRISPR Gene Dependency 1.0 3.1585 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 ELK1-19687146-Hela cells-human ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-2226-SM-3MJGP GTEx Tissue Sample Gene Expression Profiles 1.0 1.04017 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845405 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.80997 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.37943 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Poisoning CTD Gene-Disease Associations 1.0 1.35906 H3K9me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.47256 NFIC ENCODE Transcription Factor Targets 1.0 null GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 PCI4B DepMap CRISPR Gene Dependency 1.0 3.87942 FOXA2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946781 PCI30 DepMap CRISPR Gene Dependency 1.0 2.36385 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 0.844095 primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89571 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7356_KO_NSUN6_SRP233222 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 GABPA_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.913487 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.884351 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.897986 Perturb_562_KD_LMO1_SRP158473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.44726 REST ENCODE Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.363785 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06524 Lung squamous cell carcinoma_LUSC_TCGA-60-2719-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cleft palate DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.642615 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.39784 Perturb_7292_KI_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16391 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05928 Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5513 SMC3 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7443_KO_METTL21B_SRP096025 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.5856 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null USF1_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.932398 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.904077 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 LAMA84 CCLE Cell Line Gene Expression Profiles 1.0 2.08067 NCI-H1975 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null schizophrenia GWASdb SNP-Phenotype Associations 1.0 0.854378 Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7135_KD_FOXA2_SRP360959 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.37323 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-548am TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.942303 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.80136 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.86154 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.20339 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.62384 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36606 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3434 H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HT1376 CCLE Cell Line Gene CNV Profiles 1.0 2.60637 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09361 GABP-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30072 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.69509 Transcription regulator SCAN InterPro Predicted Protein Domain Annotations 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of bone marrow cell morphology GWASdb SNP-Phenotype Associations 1.0 0.258475 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5893_KD_CBX3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.29312 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 ELF1 ENCODE Transcription Factor Targets 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.81522 H3K9me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null JAR COSMIC Cell Line Gene Mutation Profiles 1.0 null MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TT CCLE Cell Line Gene CNV Profiles 1.0 1.52147 SW1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.45912 RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.920658 POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87662 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06563 NCI-H146 COSMIC Cell Line Gene Mutation Profiles 1.0 null CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835467 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.884807 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.89477 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null coronary artery disease GWASdb SNP-Disease Associations 1.0 1.50373 GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934849 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 1.09138 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28807 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null parasitic protozoa infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.208914 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.51681 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2848 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.064202 H2AK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null regulation of nucleic acid-templated transcription GO Biological Process Annotations 2015 1.0 null JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051607 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5509-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2948-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.47415 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null orofacial cleft DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.577327 HEC1A CCLE Cell Line Gene CNV Profiles -1.0 -1.86501 basal ganglia disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.174617 Perturb_13393_KD_AHR_SRP154013 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.24332 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05164 PLCPRF5 CCLE Cell Line Gene Expression Profiles 1.0 1.65623 USF1 ENCODE Transcription Factor Targets 1.0 null LB831-BLC COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_732_KD_NUDT21_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.0 golgi apparatus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 SMARCC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 MBD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MMAC DepMap CRISPR Gene Dependency 1.0 4.12558 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.62126 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924859 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BRCA1 ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.91589 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.00146 Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 dna metabolic process GO Biological Process Annotations 2015 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05974 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861174 GTEX-T2YK-0005-SM-32QOV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08338 Perturb_2552_KD_TRIM28_SRP067706 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.82507 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.61058 Prostate adenocarcinoma_PRAD_TCGA-CH-5792-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organic cyclic compound metabolic process GO Biological Process Annotations 2015 1.0 null hemoglobins GAD Gene-Disease Associations 1.0 null GTEX-W5X1-0006-SM-3GIJZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null NCIH2286 CCLE Cell Line Gene CNV Profiles -1.0 -1.33894 regulation of nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.909036 deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04027 SNU1214 CCLE Cell Line Gene CNV Profiles -1.0 -1.93651 KDM4A ENCODE Transcription Factor Targets 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.89872 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870337 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.12055 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB468 DepMap CRISPR Gene Dependency 1.0 2.30348 H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KMM1 CCLE Cell Line Gene CNV Profiles 1.0 1.72068 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.56091 Lung adenocarcinoma_LUAD_TCGA-MP-A4TF-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.09855 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00452 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.034372 GTEX-V1D1-1926-SM-4JBGX GTEx Tissue Sample Gene Expression Profiles 1.0 1.00491 H3K36me3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61615 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KDM5B_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.02873 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.63366 Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IMR32 CCLE Cell Line Gene Expression Profiles 1.0 1.63943 NH-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.89172 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EJM CCLE Cell Line Gene CNV Profiles 1.0 1.68882 Perturb_7316_KO|KD_UPF3A_ERP130416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.16546 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.50331 outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887019 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14375 regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null SKN3 DepMap CRISPR Gene Dependency 1.0 2.15477 HEC1B CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4781-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KM12 CCLE Cell Line Gene CNV Profiles -1.0 -1.95329 MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-U412-0526-SM-3DB9I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053414 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.82081 GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901071 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08345 FOS ENCODE Transcription Factor Targets 1.0 null H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TRIM28_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chronic obstructive pulmonary disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 u87 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null SIX5_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31537 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87J-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89412 CL11 CCLE Cell Line Gene CNV Profiles -1.0 -1.74836 Neoplasm Metastasis DisGeNET Gene-Phenotype Associations 1.0 null cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55361 E2F1-21310950-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GMS-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14716 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21711 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35091 TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null RELA ENCODE Transcription Factor Targets 1.0 null GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868374 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26963 GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 an3ca HPA Cell Line Gene Expression Profiles -1.0 -0.894171 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-0011-R8A-SM-4E3I5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.907524 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041474 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 skmel30 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04787 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.859792 SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5531-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059762 positive regulation of cellular process GO Biological Process Annotations 2023 1.0 null GTEX-R3RS-0008-SM-48FF1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11177 GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrovirus capsid, C-terminal InterPro Predicted Protein Domain Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Duration Of Sleep DisGeNET Gene-Phenotype Associations 1.0 null urinary tract obstruction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.590169 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16141 H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7257_KO_LARP1/LARP1B_SRP201361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.961676 JUND_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A7FE-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dna integration GO Biological Process Annotations 2015 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901071 PEO4 DepMap CRISPR Gene Dependency 1.0 4.4609 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09629 TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.13728 GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 0.983453 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19419 GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 SP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.259 Perturb_13853_KO_RET_ERP126468 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MYC ChEA Transcription Factor Targets 1.0 null dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12839 posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37373 nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.96178 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.902979 Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JW-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null schizophrenia DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.043246 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.1652 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null GTEX-X88G-0326-SM-47JZ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846385 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Secondary Malignant Neoplasm Of Lymph Node DisGeNET Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.38007 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4491 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852625 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3699 eye TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91566 NCI-H1836 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0666 SIRT6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048167 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.1743 BPH-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-548aj TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00916 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16212 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.940621 GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.824816 NCIH650 CCLE Cell Line Gene CNV Profiles -1.0 -2.07253 JUN_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4603 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 MOLT-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null striatum_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.999037 GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.890023 DEL CCLE Cell Line Gene Expression Profiles 1.0 2.45911 TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WSU-NHL COSMIC Cell Line Gene Mutation Profiles 1.0 null atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.390047 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053369 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36907 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17731 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PS-1145 DeepCoverMOA Drug Mechanisms of Action -1.0 -1.49 physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.179239 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.86249 NFIC_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.908044 GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11114 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E5-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-2726-SM-4JBH9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874369 ICC2 DepMap CRISPR Gene Dependency 1.0 2.15018 SIX5 ENCODE Transcription Factor Targets 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989446 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.91698 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.897269 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.920923 Perturb_7150_KD_SKIC2_SRP070129 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.7804 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.4264 SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42156 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.03693 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548ae TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 SMARCC1 ENCODE Transcription Factor Targets 1.0 null GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles 1.0 0.990765 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.23692 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44466 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB231 CCLE Cell Line Gene CNV Profiles 1.0 1.34237 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01102 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 Perturb_8060_KO_TP53_SRP182675 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.2212 NCIH2023 CCLE Cell Line Gene CNV Profiles -1.0 -1.68756 CEBPB ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFO21 CCLE Cell Line Gene CNV Profiles 1.0 1.62693 GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-WH7G-2326-SM-3NMBC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.858867 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K79me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-436 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.01382 GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8846 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 0.991236 cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.20846 erythroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.189746 SCH DepMap CRISPR Gene Dependency 1.0 4.57056 COLO792 CCLE Cell Line Gene CNV Profiles 1.0 1.40244 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39825 Perturb_6838_KO_DOHH_SRP199981 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.57326 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16202 EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41407 SUPM2 CCLE Cell Line Gene Expression Profiles 1.0 1.59785 FOXA2-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.40371 TAF7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RBPJ ChEA Transcription Factor Targets 1.0 null GCT COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TGW COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL1799 (BCL11B) NURSA Protein Complexes 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46755 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hl60 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 GTEX-U3ZN-1226-SM-4DXUD GTEx Tissue Sample Gene Expression Profiles 1.0 0.956401 EP300 ENCODE Transcription Factor Targets 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.50259 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00178 H3K79me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4307 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 BL2432 (NCOA5) NURSA Protein Complexes 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.61838 dna repair complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.106252 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01425 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00159 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.961676 POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922804 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HA-01B-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heterocycle metabolic process GO Biological Process Annotations 2015 1.0 null NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K9me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3928 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Perturb_7509_OE_ILF3_SRP195616 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78327 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05661 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01758 GABPA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles 1.0 0.848027 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PM-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.897666 GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859684 PGR-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null NCIH2227 CCLE Cell Line Gene Expression Profiles 1.0 1.59584 SIN3A ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.9092 Perturb_7576_KD_ZC3H4_SRP343726 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.82434 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.9521 HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.28494 HCC1143 CCLE Cell Line Gene CNV Profiles -1.0 -1.52335 OVCA433 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSE-1126-SM-3NMBU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.92579 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BATF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.45879 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67683 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040347 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.63788 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23902 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890207 T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.2831 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-0526-SM-2I3EH GTEx Tissue Sample Gene Expression Profiles 1.0 0.937254 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 0.872931 Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 SUDHL1 CCLE Cell Line Gene Expression Profiles 1.0 1.65253 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15107 Kidney renal papillary cell carcinoma_KIRP_TCGA-O9-A75Z-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.67653 Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24838 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05792 Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.8571 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30679 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 0.898482 ACN COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.72808 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.81651 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.03085 Perturb_7933_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.45767 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEG01 CCLE Cell Line Gene Expression Profiles 1.0 1.3951 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08113 H3K9me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.990595 H3K27me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049546 GTEX-RWS6-1326-SM-47JXB GTEx Tissue Sample Gene Expression Profiles 1.0 0.97283 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-X4XX-0011-R2A-SM-3P623 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934783 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7243-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05621 CHD2 ENCODE Transcription Factor Targets 1.0 null regulation of transcription, dna-templated GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18286 H3K9ac_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mRNA_SMAD7_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null JUN-21703547-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.74284 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40153 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30723 ZNF217-24962896-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QV44-0826-SM-2S1RG GTEx Tissue Sample Gene Expression Profiles 1.0 1.11277 arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.343497 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.926941 sickle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.773174 SUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 2.32637 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.77473 GTEX-XUJ4-1726-SM-4BONW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 HuTu-80 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.27664 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 NOS-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.76979 HNF4A ChEA Transcription Factor Targets 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.43924 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07576 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.26743 biological_process GO Biological Process Annotations 2015 1.0 null H3K9me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998385 Perturb_7692_KD_UPF1_SRP240357 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.54359 Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null monogenic disease GWASdb SNP-Disease Associations 1.0 0.281063 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null nucleus LOCATE Curated Protein Localization Annotations 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of cells of the erythroid lineage GWASdb SNP-Phenotype Associations 1.0 0.310248 GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27928 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16178 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19M-06A-61R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.945617 TT CCLE Cell Line Gene Expression Profiles 1.0 1.99441 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921237 BL6636 (FOXK2) NURSA Protein Complexes 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09633 Precancerous Conditions CTD Gene-Disease Associations 1.0 1.02299 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE ChEA Transcription Factor Targets 2022 1.0 null artery disease GWASdb SNP-Disease Associations 1.0 0.20468 Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27335 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3435 MXI1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21505 Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC0213 CCLE Cell Line Gene CNV Profiles -1.0 -1.48187 H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948409 sequence-specific dna binding transcription factor activity GO Molecular Function Annotations 2015 1.0 null Perturb_96_KI_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16391 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PX3G-0226-SM-3NB2C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877055 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.93183 GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898683 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24864 CEBPD_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HINFP JASPAR Predicted Transcription Factor Targets 1.0 null CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43154 cellular_component GO Cellular Component Annotations 2015 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 1.02819 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26321 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11698_KO_METTL3_SRP287496 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.99329 coronary artery disease GWASdb SNP-Phenotype Associations 1.0 1.34926 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.885609 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040852 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.54452 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.910443 H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null parafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.953621 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.905397 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of gene expression GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null non-membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900116 GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.32772 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.917419 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.860752 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01575 GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 0.891436 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PECAPJ34CLONEC12 CCLE Cell Line Gene CNV Profiles -1.0 -1.63963 MTA3 ENCODE Transcription Factor Targets 1.0 null connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045731 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00805 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.5261 GTEX-XMK1-0005-SM-4B665 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Prostate adenocarcinoma_PRAD_TCGA-EJ-5511-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17508 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.914472 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null efo21 HPA Cell Line Gene Expression Profiles 1.0 0.917404 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3609 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular aromatic compound metabolic process GO Biological Process Annotations 2015 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.935651 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.981056 CREB1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2935 CCLE Cell Line Gene CNV Profiles 1.0 1.34964 GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.02279 Perturb_4850_KD_NKX25_SRP059197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.97632 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.048335 FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079954 NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74815 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06088 LOUCY COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_7300_KO_SF3A1_SRP273617 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.43203 red nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21965 cingulate gyrus, retrosplenial part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08305 EBNA2-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.109433 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null globus pallidus, external segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.69604 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.998978 MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844205 KNS62 CCLE Cell Line Gene CNV Profiles -1.0 -2.5918 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14859 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null ovary HPA Tissue Gene Expression Profiles 1.0 1.04098 Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.061818 ATF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3-23680149-GBM1-GSC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048371 SUM1315MO2 DepMap CRISPR Gene Dependency 1.0 3.44725 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55D-1526-SM-48FEJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TCF12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Retigabine DeepCoverMOA Drug Mechanisms of Action -1.0 -0.28 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056294 osteomyelitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.812232 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.93102 regulation of epithelial cell proliferation GO Biological Process Annotations 2023 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04079 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.915261 CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_MYCN_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.991638 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.57614 GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles 1.0 0.951054 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARH77 DepMap CRISPR Gene Dependency 1.0 3.78674 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 T-00127_HEV1 DeepCoverMOA Drug Mechanisms of Action 1.0 0.39 GTEX-U4B1-1426-SM-4DXTX GTEx Tissue Sample Gene Expression Profiles 1.0 0.877451 H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67173 TGBC11TKB CCLE Cell Line Gene CNV Profiles -1.0 -2.07725 intracellular organelle part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.62294 ELK4 ENCODE Transcription Factor Targets 1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.1014 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.35028 GABPA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23144 Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QESD-1726-SM-2S1R7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-P44H-0326-SM-2XCES GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859352 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08446 blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.196393 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10018 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548ah TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22895 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.47745 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.861347 HUO9 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PML_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAL-85-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.838388 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.199033 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946781 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.343497 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IST-SL1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04101 Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.97696 GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 1.41892 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054427 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 2.07515 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971623 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946781 EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER ChEA Transcription Factor Targets 2022 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-T6MN-1126-SM-4DM71 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842654 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0006-SM-2TC5G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPIC-0226-SM-3GADO GTEx Tissue Sample Gene Expression Profiles 1.0 0.880953 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.32987 FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.7914 H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TEAD4_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02012 GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.23664 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02962 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17192 Thiamet G DeepCoverMOA Drug Mechanisms of Action -1.0 -0.31 RERFLCKJ CCLE Cell Line Gene CNV Profiles 1.0 1.35502 Perturb_4855_KD_ZNF503_SRP059197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.36104 TAF1_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.996603 CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63052 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901071 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.974216 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.876933 GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 0.986594 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16322 SC-9118 (PDPK1) NURSA Protein Complexes 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.919697 GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null J82 CCLE Cell Line Gene CNV Profiles 1.0 1.89588 H3255 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.13348 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.93052 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2548_KO_MLL3_SRP163132 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.14871 GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 0.866016 abnormality of erythrocytes GWASdb SNP-Phenotype Associations 1.0 0.310248 EJM DepMap CRISPR Gene Dependency 1.0 2.22027 MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19249 Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.34902 EZH2 ENCODE Transcription Factor Targets 1.0 null H3K4ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 genetic disease GWASdb SNP-Disease Associations 1.0 0.255407 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.63496 GTEX-NFK9-0226-SM-2HMKQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824475 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05759 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.895928 erythroid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.189746 blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079316 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.98837 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34971 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.52372 PML ENCODE Transcription Factor Targets 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null retina TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary motor cortex (area M1, area 4)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10256 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.16696 MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4737-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SU-DHL-4 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.03942 POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.836784 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854196 H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 MDST8 COSMIC Cell Line Gene Mutation Profiles 1.0 null HT55 CCLE Cell Line Gene CNV Profiles -1.0 -1.35741 cytoplasm LOCATE Curated Protein Localization Annotations 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36328 MAX ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-7961-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.16213 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01973 ETS1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Coronary Heart Disease DisGeNET Gene-Disease Associations 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.133987 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05661 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null substantia nigra, pars reticulata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25244 TAF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14304_KD_HNRNPC_SRP230637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.88758 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72096 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.973408 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null psychotic disorder GWASdb SNP-Disease Associations 1.0 0.32187 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.909036 H3K9ac_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.86443 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7315_KO_UPF3A_ERP130416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.47166 HDQ-P1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 SCH 58261 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.25 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.49515 nucleic acid binding transcription factor activity GO Molecular Function Annotations 2015 1.0 null hydronephrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.86018 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0365 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null palate TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.813562 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.95904 Perturb_14287_KD_TENT4A_SRP237261 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.00962 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.890884 Perturb_7377_Mut_PHF3_ERP112687 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.43416 BACH1 ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04912 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936358 disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 Lung squamous cell carcinoma_LUSC_TCGA-77-8139-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sense organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.875509 ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.947287 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.963818 YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0228 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 0.940484 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null hmc1 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.950764 GTEX-VUSG-0426-SM-3GIKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.06432 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JZ-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 nuclear lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 HDAC2 ENCODE Transcription Factor Targets 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888751 GTEX-RM2N-0526-SM-2TF4N GTEx Tissue Sample Gene Expression Profiles 1.0 0.928838 SP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05822 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052849 TUHR14TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.4706 GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15208 GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 PADI4-21655091-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.173347 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.917015 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 spleen HPA Tissue Gene Expression Profiles -1.0 -1.12289 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.93879 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32144 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.17903 CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35515 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.868205 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.56417 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06867 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 1.18188 FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Perturb_3515_KD_EIF4A3_ERP130710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.8366 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.878962 primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.928675 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868892 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.976433 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Capsazepine DeepCoverMOA Drug Mechanisms of Action 1.0 0.93 MYBL2 ENCODE Transcription Factor Targets 1.0 null parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.162908 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.33139 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23405 amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.78882 thyroid gland HPA Tissue Gene Expression Profiles 1.0 0.984777 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2085 H4K5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null frontal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.891609 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7256_KO_LARP1_SRP201361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null VMRC-RCZ COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21971 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921237 disease GWASdb SNP-Disease Associations 1.0 0.037736 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.56864 GTEX-SJXC-0226-SM-2XCDU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32756 COLO792 DepMap CRISPR Gene Dependency 1.0 3.04512 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUPT3 CCLE Cell Line Gene CNV Profiles 1.0 2.94091 H3K79me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975886 mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.30947 EFO21 CCLE Cell Line Gene Expression Profiles 1.0 1.88563 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.52596 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null NCIH226 DepMap CRISPR Gene Dependency 1.0 4.98115 HDAC1 ENCODE Transcription Factor Targets 1.0 null GTEX-R55C-1026-SM-48FCM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834826 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.842692 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14714 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.95145 regulation of biological process GO Biological Process Annotations 2015 1.0 null layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.921342 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.937823 anemia GWASdb SNP-Phenotype Associations 1.0 0.369844 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946781 cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.28832 erythrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.193924 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4II-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.887419 HUPT3 CCLE Cell Line Gene Expression Profiles 1.0 1.42388 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40086 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null normoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.189746 nucleolus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3915 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null regulation of primary metabolic process GO Biological Process Annotations 2015 1.0 null Nateglinide DeepCoverMOA Drug Mechanisms of Action 1.0 0.71 disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.043246 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Non-Small Cell Lung Carcinoma DisGeNET Gene-Disease Associations 1.0 null COLO-741 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07468 POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.76498 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31592 GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 1.18845 ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.882124 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947499 Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00117 amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.965931 HT-1376 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.7109 cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.043246 GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 FOXA1 ENCODE Transcription Factor Targets 1.0 null Perturb_6711_KD_STAU1_SRP266909 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.56745 cerebral malaria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.767576 Hemoglobins dbGAP Gene-Trait Associations 1.0 0.346272 GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.955181 DNAJC2 ChEA Transcription Factor Targets 1.0 null outer SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05113 Inflammation CTD Gene-Disease Associations 1.0 1.04314 hsa-miR-3647-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 BHLHE40 ENCODE Transcription Factor Targets 1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -2.05731 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.12256 vascular disease GWASdb SNP-Disease Associations 1.0 0.154333 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.16937 TT COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R53T-0526-SM-3GADL GTEx Tissue Sample Gene Expression Profiles 1.0 0.959016 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V1D1-0926-SM-4JBHQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.86844 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 2.40718 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901071 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885069 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.946781 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043576 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.843931 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.91689 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965509 GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.967586 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2179 inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07014 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68454 PPARA_agonist activation_GSE17251_474_human_Isolated hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null T3M4 DepMap CRISPR Gene Dependency 1.0 4.64226 POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN JASPAR Predicted Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08373 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12196 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846142 GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 0.869152 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042793 EW-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11397 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.877791 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216933 Icatibant DeepCoverMOA Drug Mechanisms of Action 1.0 0.32 POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COR-L26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.82794 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00024 E2F6 ENCODE Transcription Factor Targets 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55927 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_10149_KO_FOXK1_SRP251223 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49836 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OC-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 2.10077 GTEX-X8HC-0226-SM-4E3K1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860683 MBD4_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 1.14684 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null schizophrenia GWASdb SNP-Disease Associations 1.0 0.969909 ELK1 ChEA Transcription Factor Targets 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33075 Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02313 muscle GTEx Tissue Gene Expression Profiles -1.0 -2.01562 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1 JASPAR Predicted Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34596 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71207 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901071 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.67315 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.33664 CREB1 ENCODE Transcription Factor Targets 1.0 null nucleic acid binding GO Molecular Function Annotations 2015 1.0 null GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28717 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16759 Perturb_10168_KO_TOP2A_SRP297586 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.2263 BATF ENCODE Transcription Factor Targets 1.0 null skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -0.902877 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5329-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_524_KD_RL6/BRF1_SRP382324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.26581 TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37647 lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.899821 adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069845 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.876176 MSTO-211H Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.04953 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08113 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.77843 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF7 ENCODE Transcription Factor Targets 1.0 null GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.22716 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -0.952348 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.42728 Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null u937 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 USF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7625_KD_ICE1_SRP120604 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.0686 H3K23ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06434 CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.390047 GTEX-OOBK-0226-SM-2YUMF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null Detroit562 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.67831 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4426-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null TCF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.84214 RCC-MF COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.949959 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16587 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 regulation of rna biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11964 SP2 ENCODE Transcription Factor Targets 1.0 null skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.6257 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.23642 kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.074222 Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD4_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.903719 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-323b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GTEX-SNOS-0008-SM-4DM6I GTEx Tissue Sample Gene Expression Profiles 1.0 0.861431 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13879 Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046704 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0326-SM-3LK6Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.971327 Perturb_1251_KO_MED1_ERP116563 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.71631 GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.10323 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50079 TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.28295 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881953 ELF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23618 SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.25637 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC-56 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 MITF ChEA Transcription Factor Targets 1.0 null KOPN-8 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.54317 Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 0.85011 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.74535 hsa-miR-4305 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Squamous Cell Carcinoma Of Esophagus DisGeNET Gene-Disease Associations 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26239 Lung adenocarcinoma_LUAD_TCGA-78-7158-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TCF12 ENCODE Transcription Factor Targets 1.0 null NR3C1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852625 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20751 primary metabolic process GO Biological Process Annotations 2015 1.0 null membrane-enclosed lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.876472 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null K562 CCLE Cell Line Gene Expression Profiles 1.0 3.39831 uterus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-S4Q7-1026-SM-4AD75 GTEx Tissue Sample Gene Expression Profiles 1.0 0.975527 organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00836 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4967-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null molt4 HPA Cell Line Gene Expression Profiles -1.0 -0.894171 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 CEBPB_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-O8-A75V-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1121_KD_E2APBX1_SRP115954 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.10884 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.970817 15489324-TableS2 GeneSigDB Published Gene Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.934732 E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71926 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null CEBPB_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44544 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of cell cycle GO Biological Process Annotations 2023 1.0 null BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859119 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.870364 Perturb_3799_KD_ZNF281_SRP377192 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.76459 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.55247 H3K79me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8308-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.69431 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA2_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00436 GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.37474 regulation of cellular macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.950313 Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWSA-1326-SM-47JX9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847842 SUPHD1 CCLE Cell Line Gene Expression Profiles 1.0 1.73551 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA2 ChEA Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12035 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null Perturb_7665_KO_SNORD45C_SRP257547 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.60315 ZNF217 ChEA Transcription Factor Targets 1.0 null GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EMC-BAC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06304 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.910432 GABPA_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-S341-1726-SM-3K2AK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 STAT3 ENCODE Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bonemarrow_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01123 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.956032 Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-TKQ1-0526-SM-4DXTG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null T98G DepMap CRISPR Gene Dependency 1.0 2.42623 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5765-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7357_OE_RBFOX1_SRP307800 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.79227 IGR39 CCLE Cell Line Gene CNV Profiles -1.0 -1.4068 CEBPB_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.864854 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 1.31999 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of cell cycle GO Biological Process Annotations 2023 1.0 null H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.28379 Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.896244 DMS114 CCLE Cell Line Gene CNV Profiles 1.0 1.34507 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888751 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.909242 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A64Z-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 protein dimerization activity GO Molecular Function Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1482 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null AM095 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.3 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21428 Brain Lower Grade Glioma_LGG_TCGA-QH-A6X9-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT3 DepMap CRISPR Gene Dependency 1.0 2.32752 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.853409 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 1.01239 hsa-miR-548g TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null sickle cell anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.200331 Perturb_7614_KO_LARP1/LARP1B_SRP201361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 body of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.944587 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4639-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND JASPAR Predicted Transcription Factor Targets 1.0 null EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.24616 PADI4 ChEA Transcription Factor Targets 1.0 null nuclear part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7842-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMK1 DepMap CRISPR Gene Dependency 1.0 5.26963 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.919424 RAD21_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPD ENCODE Transcription Factor Targets 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.76472 Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.1195 Ribonuclease H-like domain InterPro Predicted Protein Domain Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4965-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964897 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.898822 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850986 TAF1 ENCODE Transcription Factor Targets 1.0 null GS-9620 DeepCoverMOA Drug Mechanisms of Action 1.0 0.4 H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56899 GTEX-X5EB-1826-SM-4E3K8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.990935 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.25422 COLO-680N Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.39748 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.52628 membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OHPM-2626-SM-33HC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01144 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886563 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.914017 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71207 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00831 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWN1-0226-SM-2S1OZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MBD4 ENCODE Transcription Factor Targets 1.0 null GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles 1.0 0.916317 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11267 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07788 REST_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.823927 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37345 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.833833 GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles 1.0 0.873555 pronephros TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.622639 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.63626 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WYVS-1726-SM-3NMAY GTEx Tissue Sample Gene Expression Profiles 1.0 0.85821 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2711-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.849061 GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 capillary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.261284 ZEB1 ENCODE Transcription Factor Targets 1.0 null PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24283 molecular_function GO Molecular Function Annotations 2015 1.0 null autosomal recessive disease GWASdb SNP-Disease Associations 1.0 0.429365 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04973 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null bone marrow HPA Tissue Gene Expression Profiles -1.0 -0.886739 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.851175 GTEX-XMD3-0008-SM-4AT4V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844729 respiratory system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QS-1826-SM-2S1NI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RVH421SKINFV1 DepMap CRISPR Gene Dependency 1.0 2.34498 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of rna metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 2.16185 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970336 SREBF2 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.070131 NCI-H1155 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_13852_KO_RET_ERP126468 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21204 stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60768 Domain of unknown function DUF4371 InterPro Predicted Protein Domain Annotations 1.0 null POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 hsa-miR-342-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nonhomologous end joining complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.751357 bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.067983 SIRT6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.980168 GTEX-P78B-0526-SM-2I5F7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.928054 GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86285 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-1080-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TBP ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC4006 CCLE Cell Line Gene CNV Profiles -1.0 -1.37909 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 0.82617 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Perturb_12580_OE_STK32B_SRP261296 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.17994 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.881126 BT-483 COSMIC Cell Line Gene Mutation Profiles 1.0 null ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6211 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 1.22689 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.28279 RBBP5 ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867552 reticular nucleus of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31218 D-336MG COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31767 Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null THP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.34721 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08006 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4UY-0006-SM-3K2A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 serum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.606514 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36242 synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.130905 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0145 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31723 GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.31032 prostate HPA Tissue Gene Expression Profiles 1.0 0.915851 NCI-H1755 COSMIC Cell Line Gene Mutation Profiles 1.0 null MCF7 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.32707 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2882 DepMap CRISPR Gene Dependency 1.0 2.48887 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 1.05787 BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20525 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40401 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GABPA_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.947287 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043567 GTEX-WFON-2326-SM-3LK7M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948998 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.30794 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.34764 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.2698 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29376 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0826-SM-2HMKF GTEx Tissue Sample Gene Expression Profiles 1.0 0.91404 ATF3 ChEA Transcription Factor Targets 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus GO Cellular Component Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92345 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.898 GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31592 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null globus pallidus, internal segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.56001 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854196 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26091 cell part LOCATE Curated Protein Localization Annotations 1.0 null cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.42545 H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.829966 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 MOGGUVW DepMap CRISPR Gene Dependency 1.0 2.27396 hsa-miR-466 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69617 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13517 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25267 GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.14661 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.93247 KARPAS-1106P COSMIC Cell Line Gene Mutation Profiles 1.0 null RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 TCF7L2 ENCODE Transcription Factor Targets 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850528 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.77966 zona incerta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.848604 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-V955-0426-SM-3GAEL GTEx Tissue Sample Gene Expression Profiles 1.0 0.971169 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.921519 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04811 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-421 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 RAD21 ENCODE Transcription Factor Targets 1.0 null GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Perturb_15995_KD_LUCAT1_SRP221619 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.77608 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13805 Perturb_563_KD_MYCN_SRP158473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.22422 obstructive lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLR21 CCLE Cell Line Gene Expression Profiles 1.0 1.45296 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-SNOS-0526-SM-4DM54 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835596 HCC1419 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.93167 KYSE150 DepMap CRISPR Gene Dependency 1.0 2.19253 MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7388-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10014 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98055 MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55473 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK4_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.866753 Perturb_3667_KO_FASTKD_SRP277516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.3199 POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-XMD3-2326-SM-4AT5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.980074 skin_6a HPA Tissue Sample Gene Expression Profiles -1.0 -0.935504 MYC_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of metabolic process GO Biological Process Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.88482 SIRT6 ENCODE Transcription Factor Targets 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040456 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 RPMI8226 DepMap CRISPR Gene Dependency 1.0 9.96084 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 FOXA2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null D341MED CCLE Cell Line Gene Expression Profiles 1.0 1.43286 intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles 1.0 0.849301 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.92387 anemia due to reduced life span of red cells GWASdb SNP-Phenotype Associations 1.0 0.412939 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.2339 motor neuron disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EM2 CCLE Cell Line Gene CNV Profiles 1.0 2.03427 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null autosomal genetic disease GWASdb SNP-Disease Associations 1.0 0.30996 psychotic disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.043246 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.986653 TEAD4 ENCODE Transcription Factor Targets 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-T5JW-0008-SM-4DM5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.00248 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.12256 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XAJ8-0326-SM-47JYI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835528 GTEX-R55F-1726-SM-2TF4R GTEx Tissue Sample Gene Expression Profiles 1.0 0.865679 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50243 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 GTEX-XYKS-1626-SM-4BRUQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.913305 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X261-0226-SM-3NMD2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90869 H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040909 GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04188 GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.919781 YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97701 Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7314_KO|KD_UPF3A_ERP130416 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.22614 SP2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-2026-SM-3LK7U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35273 Perturb_7328_KO_KMT2C_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.0424