association	dataset	threshold value	standardized value
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13320013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55137
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.10905
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09468
DACH1-20351289-CHIP-SEQ-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.13361
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tracheobronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62312047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6095
Focal adhesion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24234
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14875
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02121
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364358
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
CEBPZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
CRCGN015_MCF10A_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05481
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDE1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717121
BRD-K85627183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1527
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.974642
SP4	ENCODE Transcription Factor Targets	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.52131
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04972
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07589
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K25791914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57505
GTEX-WEY5-0826-SM-4LMIH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862489
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39653
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.910054
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42553
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28885
BRD-K17233342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06933
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989799
CRCGN015_MCF10A.TP53.M_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16065
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49169
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42877297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0673
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72413
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50918
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04051
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996354
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24823
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4753
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970018
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82296
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69365
BRD-K98535708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80663
PLK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488837
PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67830713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15277
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFE2	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
6537_POLR1D_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.548406
A549_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144612
BICR16	CCLE Cell Line Gene CNV Profiles	1.0	2.25655
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2267
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80415
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03014
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.14116
Hematologic Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.072
MET_knockout_257_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.59755
benfluorex-5327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23353
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81052
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PEBP1_KO_GSE31150_52_mouse_pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83014
aspects	GeneRIF Biological Term Annotations	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43931
SULT2A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509707
BRD-K22510845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94657
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05629
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MK-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2715
BRD-K15259298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10538
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67326
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20647
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.07553
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43809
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-6.03567
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412318
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930432
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37067
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03324
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78665
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1279	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.680284
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64688
inferior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03756
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8062
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90594901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38807
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A824-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70222
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835929
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483113
BRD-K92359570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73401
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K68953461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45818
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K81725246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0091
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rabies CVS-11_7day-Spinalcord_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67334
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.89216
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20762
layer III of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976711
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35216
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886636
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.10961
NRF1	ENCODE Transcription Factor Targets	1.0	null
SKRC31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81255
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08856
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981401
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40375
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A539-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01543
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26736
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27341
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.132
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996671
LN443	CCLE Cell Line Gene CNV Profiles	1.0	1.346
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A8YN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29353
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469492
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.385653
BRD-K21879622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11178
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04043
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5366-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOM1	CCLE Cell Line Gene CNV Profiles	1.0	1.33582
16618758-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00407008
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	8.42672
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18128
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17253
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872675
CRCGN016_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29817
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53781
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30006
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61561
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404558
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40177
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00238
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00857
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
focal adhesion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4726-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11516
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76419
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40347
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233131
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935118
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14268329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26451
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Infertility, Male	CTD Gene-Disease Associations	1.0	1.38891
FOS_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HUNS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51395
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19574
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20947
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07937
1381_CD99L2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.727923
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43515
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.7942
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02288
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K15499806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26182
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33079
BRD-K28139946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46778
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4643
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87209752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11056
5933_OGT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507619
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90155
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46372
BRD-K98095706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0215
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56938
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67436
BRD-K81104218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31989
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65278
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.63674
BRD-K05970499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41861
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31663
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0626-SM-4DM62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35256
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56351
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957419
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09796
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96818
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34317
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235672
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06405
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZP-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62225
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12493093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69594
BRD-K13235291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16682
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78352
hsa-miR-4422	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
PMC7320752__F6	PFOCR Pathway Figure Associations 2023	1.0	null
AKT1_activemutant_9_GDS2304	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.95523
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04213
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939909
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875517
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985176
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32326
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991713
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73969016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27716
TBX5	ChEA Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05304
Perturb_3922_KD_VPS37A/VPS37C_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.44229
Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K92700781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63846
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05445
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920472
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.36003
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15614
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-02-SI44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289193
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16131
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91049
BRD-K39715006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4744
CEBPB	ENCODE Transcription Factor Targets	1.0	null
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-263-YY1_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82448
phenacemide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03111
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.448346
Early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.388
heptaminol-1825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89063617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89695
ERBB2_overexpression_230_GSE14990	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.22318
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67098
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4084
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986479
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OD-96-OP94_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225687
19204204-SupplementaryTable1	GeneSigDB Published Gene Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872355
KMT5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00474208
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1252
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10435
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.10417
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.161535
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
Skin Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27882
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00723
BRD-K49409924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73005
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MH-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13353
bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K28467941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56693
SOX9	ChEA Transcription Factor Targets	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60198
BRD-K43053725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21988
acetazolamide-1808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76415727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.128
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00352
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.86312
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08385
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42945
DKC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568622
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XQ8I-0326-SM-4BOPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08368
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0426-SM-47JX3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5684
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89458
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00084
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885518
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6209
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57388326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49373
BRD-K50716325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21757
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Granulosa cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09195
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.47448
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20527
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64494
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.86379
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8696
BRD-K10900122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18041
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02893
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07409
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999265
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.182
MCF7_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173187
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01334
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.96405
AB-04-NN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360516
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07123
PMC10789742-41419_2024_6441_MOESM2_ESM.xlsx-S9_ZBTB7B_signature-Table_S9_Summary_of_ZBTB7B_signature_ZBTB7B	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A17043706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03489
BRD-K34534297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93104
brinzolamide-1615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-148	GDSC Cell Line Gene Expression Profiles	1.0	1.68223
BRD-K04196669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84421
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78052
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64547
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18094
PMC7529806-41467_2020_18638_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_TG_of_EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0544
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307325
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354178
nifedipine-1856	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.10955
focal	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02996
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00303
Prostate	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.21671
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870872
BRD-K75220555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00035
BRD-K11662217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16187
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.03066
BRD-K63614330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14964
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
iohexol-2461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43167
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMBT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00713986
BRD-K62068620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51377
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31612
SP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K14117311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74658
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1306
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01537
BRD-K40306365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14103
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852348
MCF7_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167818
BRD-K79352289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16511
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927634
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04275
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52213
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16136457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14884
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.984
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5928
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834252
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31030467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11955
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.40617
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3321
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.848886
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	2.29478
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-A27056524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44027
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.945702
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0656
RUNX1-22343733-KASUMI1-HUMAN-PERIPHBLOOD-AML	ChEA Transcription Factor Targets 2022	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30475
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.20027
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.21053
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A538-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-2126-SM-4JBJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854359
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33797
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15322427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33273
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903913
Sarcoma_SARC_TCGA-MB-A5YA-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3012
T98G	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72165
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70468140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04539
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29681
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22526
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9113
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00792
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7025
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
benfluorex-1266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.87858
Zinc finger, FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.181
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.661693
BRD-K04143388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10769
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00624
HCV JFH1_120Hour-Huh7_5_1_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.69842
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
member	GeneRIF Biological Term Annotations	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.2061
BRD-K87930002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30649
PMC8045172-13018_2021_2402_MOESM1_ESM.txt--AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32617235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04831
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.24244
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051096
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69257
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10343
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12345
BRD-K73210450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06967
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20175
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994962
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437205
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16315
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16184
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23783
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920373
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92131
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56341
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TNFRSF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32875
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05881
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02829
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06145
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2374
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.221
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-00-YJ41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207977
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61029307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65654
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K34110797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17972
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44847
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_6_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00022
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60785
HCC78	DepMap CRISPR Gene Dependency	1.0	2.47197
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.643086
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24117
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32392
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.06122
BRD-K63545954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06143
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74306
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04516
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33109
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIX-Logfold_change_threshold_1_0_1_NFIX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03810133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6926
disassembly	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74423
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.880004
BRD-K64268886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02049
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF15_KO_GDS4780_419_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17806
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79912
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01681
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06317
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2776
CORL47	DepMap CRISPR Gene Dependency	1.0	3.40583
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.6837
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923814
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
NCIH522	DepMap CRISPR Gene Dependency	1.0	3.7346
H3K36me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H12D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13024
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49719
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76023734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44335
LOUNH91	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38109
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02781
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM19	CCLE Cell Line Gene Expression Profiles	1.0	1.44013
SUZ12	ChEA Transcription Factor Targets	1.0	null
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTV-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97981
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972918
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13253
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
FYVE zinc finger	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75935
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42728
GTEX-W5WG-1026-SM-4LMIF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883625
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205556_1_v_0_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3494
19286929-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K37062347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15035
BRD-K92759025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18736
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46989
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9393
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K86750448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4759
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.800905
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.91701
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19421
etiocholanolone-4298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38621
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05848
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.73978
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986487
DA-58-LZ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295781
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17202
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60071
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5623
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.685
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04874
ETS1	ENCODE Transcription Factor Targets	1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28214
BRD-K45013226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15654
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-substrate adherens junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042745
T47D	GDSC Cell Line Gene Expression Profiles	1.0	1.52028
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
18535662-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930245
CA-56-GE89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214728
BRD-K76067434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34479
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5676
Lung adenocarcinoma_LUAD_TCGA-44-2655-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67239
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0926-SM-4IHKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14825
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.424
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20407
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4677-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84303
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23933
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867561
acepromazine-1777	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08785
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62827
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94452277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06993
N6-methyladenosine-1271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36833
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36177
OVCAR3	BioGPS Cell Line Gene Expression Profiles	1.0	1.16165
PMC4521181-oncsis201520x8.pdf-149-RREB1_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K19344710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21511
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039668
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15875
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2601
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072449
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04049
Brain Lower Grade Glioma_LGG_TCGA-FG-7638-01B-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00711873
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161827_0_v_3_ertugliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1085_KD_MYEOV_SRP242311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.858289
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47426
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00601
Lung squamous cell carcinoma_LUSC_TCGA-77-8130-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4641
EC-98-YS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248594
LD-48-CY61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255761
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991246
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48326
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR7530	CCLE Cell Line Gene Expression Profiles	1.0	1.93912
ZNF583	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20328
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399258
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.031
MAFK	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3978
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PM-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905831
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.158
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21336
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A47B-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84013239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76769
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859552
DAPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714317
BRD-K62612761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25705
BRD-K19183365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36204
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72811
hsa-miR-484	MiRTarBase microRNA Targets	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35122
10702_ZNHIT6_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.05535
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51602
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.51904
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9143
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09068
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878479
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12387
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66716
rt4	HPA Cell Line Gene Expression Profiles	1.0	1.25076
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20429
CRCGN009_HEPG2_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74372
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LC-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.10251
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84939696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71934
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08421
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64489
KDM1A	ENCODE Transcription Factor Targets	1.0	null
BRD-K29549246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76737
BRD-K72424071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2877
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K03546460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05397
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53982
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215035
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39629
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31437
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6491
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874866
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00152
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1198
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839768
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.21089
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50177531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15008
hsa-miR-4690-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03685
PPARG-19300518-CHIP-PET-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0333
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3513
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.846
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K26748243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79108
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12819
BRD-K69048559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01377
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22536
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70425
USF2	ENCODE Transcription Factor Targets	1.0	null
BRD-K11275619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27582
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44166
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08141534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4014
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57162
EFM192A	CCLE Cell Line Gene Expression Profiles	1.0	1.37606
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07206
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400438
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06385
GTEX-XYKS-1026-SM-4BRVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824208
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIVF001-017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10476
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VAT1	Pathway Commons Protein-Protein Interactions	1.0	null
IFNA17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667232
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40841
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4164
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28214
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
icSARS CoV_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31499
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47985
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.771815
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81896
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-10	GDSC Cell Line Gene Expression Profiles	1.0	1.57061
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86855109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0985
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fusaric acid-3245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47036
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22045035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10743
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.703181
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08607
GTEX-S3XE-1226-SM-4AD4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984721
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837026
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8833
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
16484322-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.850782
BRD-K47292239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04849
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3636
Hepatitis C infection_Hepatocyte_GSE2067	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.01875
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883201
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21242
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15531
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.44452
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1172
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923618
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05305
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587998
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74137
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454126
hsa-miR-548ah	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19049
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06234
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43843
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36764
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82509605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00439
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.95425
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00507
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114992
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.753318
Anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35157
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31253
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
8835_TFAP2B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.704761
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.08095
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03126
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.907007
hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hydrocortisone_homo sapiens_gpl570_normal scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35035
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01342
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40332193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09986
BRD-K67873600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0441
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K13289658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26374
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955178
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36795
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03038
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.827173
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910221
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1109
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	1.69111
emetine-4827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45103
BRD-K23857235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82488
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12501
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89463
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95822
BRD-K71561082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12983
PMC7280757__F3	PFOCR Pathway Figure Associations 2024	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77169
initiation	GeneRIF Biological Term Annotations	1.0	null
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00036
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49156
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19558
RT112_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	3.30131
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53774433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61194
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0336
MCF7_UNC0631_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185742
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.901856
BE2M17	DepMap CRISPR Gene Dependency	1.0	3.69822
brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85832
BRD-K26024910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11902
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48394
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.21148
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0526-SM-3MJHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882447
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.504724
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23122
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918015
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.797
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35844
NCI-H64	GDSC Cell Line Gene Expression Profiles	-1.0	-2.40099
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13868
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.077
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.20198
BRD-K97624853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05397
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RSV_24Hour_19459069_GSE3397	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.60663
cefalexin-1273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K21051792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26861
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413482
GK_KO_GDS1555_127_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.907699
Prostate adenocarcinoma_PRAD_TCGA-CH-5750-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
AA-67-TF79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212426
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08829
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26847
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57269
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05932
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44902
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61322
BRD-K83109105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46157
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830751
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19896
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.249
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.79822
hsa-miR-4719	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32572
BRD-K56119660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0348
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34788
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, ventrolateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37851
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05599
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
BRD-K03312699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12682
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76521
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09304
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878728
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05831864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1006
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.254
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1-cell stage cell (Blastomere)_Embryo_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
DACH1	ChEA Transcription Factor Targets	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09658
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95706
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16455954-TableS1	GeneSigDB Published Gene Signatures	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.861917
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05568
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14039
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12729
PLCXD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429909
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0424
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14167
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62021
MCF7_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141619
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LE-80-QM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338791
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2229
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5527
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974793
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34258713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82053
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-SE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.464
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36253
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0879
lymphnode	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01919
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90846
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49966
BRD-K90311252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49203
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983492
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.929419
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
GSE158834_1_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8253095-MOL2-15-1942-s005.xlsx-gene_lists-Genes_associated_with_H3K27ac-positive_sample_selective_AR_sites_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840797
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129308
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51409
orlistat-6905	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876988
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05722
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225009
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09395
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5427
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01638
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9161
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1102
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67409155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4842
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2246
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13528
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04943
MYC	ENCODE Transcription Factor Targets	1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53025
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.37894
MEC1	DepMap CRISPR Gene Dependency	1.0	2.56024
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13352
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0326-SM-3NB3R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984552
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS695T_SKIN	CCLE Cell Line Proteomics	1.0	2.54406
BRD-K58268854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14191
16565969-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61826
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21369
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04875
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82997
SRF	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10314
Kidney Chromophobe_KICH_TCGA-KL-8326-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
BRD-K75514760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73019
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56792
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SL-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5926_KD_LOXL2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.05318
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952349
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06081
BRD-K47599758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28174
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54228
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K35058762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27466
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834085
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05143
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0153
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56661847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70175
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02218
PMC7339546-12915_2020_793_MOESM2_ESM.xlsx-Table_S12-Table_S12_common_twin_genes_in_one_HMR_core_region_between_cattle_and_human_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10093
BRD-K19608864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02134
H3K36me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901739
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10361
A204	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07377
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06535
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21981
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03468
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8246
MAP3K13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049919
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904509
SLC7A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605257
ZBTB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06415
8331_SPC24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.532711
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53358
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.78238
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157555,GSE157556_5_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-142-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62197
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20445
FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58371
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32686643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0885
BE-82-TS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218576
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.36508
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
BRD-K87951090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2997
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.4591
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53107
BRD-K88278778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1799
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043296
BRD-K55916310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04683
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89452
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.11997
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05145
NDUFA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00400714
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42697
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
BRD-K14327064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07764
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27438
BRD-K47409867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28247
BRD-K61223323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28866
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82638914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25044
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78343
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84915
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1839
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23974
4470_KRI1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.562593
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A63590986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0868
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49917
tribenoside-6328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95501793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06487
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46427
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979103
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.70744
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT4	CCLE Cell Line Gene Expression Profiles	1.0	1.79036
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15951
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22866
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23804
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70886325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68256
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3403
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59246
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47504528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00916
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33103
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37461
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895213
hsa-miR-3609	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867794
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.716729
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KB-88-OR49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24914
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01342
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919541
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13077
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832766
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05796207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26724
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20647
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07816
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36753
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28214
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.50118
LCL161	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.54
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5556
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921802
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.34504
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.3514
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843942
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30954
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853561
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76733
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13053
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48268
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
EW-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66F-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27028848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38157
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339289
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903124
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0176
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12853
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K50240676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23386
PA-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51235
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18227
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64896
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26909
focal adhesion	GO Cellular Component Annotations 2015	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33178
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52457
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14026
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924093
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00178
BRD-K50413145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80947
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53383
Perturb_4263_KO_OTX2_SRP388433	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.61921
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109671
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61923
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934833
Pamoic Acid	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.55
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K13968264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16471
Clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_6_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
pyridoxine-1759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93606
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3943	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44520987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7807
hsa-miR-921	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253916
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13151
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50232
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987491
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
tretinoin-1636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Rkip1_KO_GDS4331_15_mouse_C57BL/C pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33158
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAK	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44966
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09781
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82162
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02187
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50709
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	1.56818
BRD-K52341452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26322
BRD-K13370005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.221
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06957
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20435
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265562
BRD-K44613656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1418
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.15862
FARAGE	DepMap CRISPR Gene Dependency	1.0	5.79282
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59556
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Astrocyte_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
Perturb_3146_KO_Mrfta/Mrtfb/Myocd_SRP388810	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.68602
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00974
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.889295
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59672
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42825
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.983878
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917806
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0307
BRD-K36464765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00356
AC-71-YF45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432182
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1093
BRD-K68305833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62512
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49229
RPMI-8866	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7517
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VPC23019	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87789
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40026
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	6.27809
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14597_KD_MYEOV_SRP242311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.4231
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13404
protein binding	GO Molecular Function Annotations 2015	1.0	null
LTB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576782
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58758
BRD-K10943878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10573
Sarcoma_SARC_TCGA-PC-A5DL-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15879
BRD-K12836153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44432
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57125
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.844932
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54399
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.79016
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0456
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
BD-85-GY20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242909
BRD-K96968070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22103
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991785
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.15229
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52145
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7171
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	14.6595
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23673
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04947
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33268
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08022
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25066
Ibutilide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
josamycin-2034	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18209
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48087
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.519
GTEX-OXRK-1426-SM-3NB19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982768
NR2C2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	ENCODE Transcription Factor Targets	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K63394284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5308
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16542
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0933
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06667
triprolidine-2376	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11495
BRD-K07550833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48263
NCI-H1694	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39249
CRCGN011_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41
ZR75_1	BioGPS Cell Line Gene Expression Profiles	1.0	1.01838
BRD-K91277001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18111
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	1.53511
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nocodazole-6793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11504077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46019
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05082
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
center	GeneRIF Biological Term Annotations	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28195
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_17437_KO_Usp7_SRP256242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.83273
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22322
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941395
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73177528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30254
PNU-0293363-6573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488699
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7745
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452969
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
invasion	GeneRIF Biological Term Annotations	1.0	null
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31914
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40867
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87403
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33215
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00128
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06842
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28292
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7114
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21449711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20955
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25547
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85513337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52889
NE-37-JX51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2204
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24635
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84205
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1746
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239898,GSE239899_1_v_0_hiltonol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00857
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16643655-1300GenesList	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136292
STAT3	ENCODE Transcription Factor Targets	1.0	null
BICR22_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.09376
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24749
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26268
BRD-K92949288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05617
AG-012559-6920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10558
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991482
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35262
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59946
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7612
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13881
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06452
DACH1-20351289-MDA-MB-231-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49244
Perturb_15594_KD_PPARG_SRP049523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12755
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3174	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
IGFBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53784
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76056
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04754
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75175
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25631
nilutamide-5362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01234
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.825992
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291677
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5329
MTA3	ENCODE Transcription Factor Targets	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10539
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7114
genistein-5232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968316
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59819
MB-32-LQ97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329945
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
srf_20709909_hematopoietic_stem_cell_lof_mouse_gpl1261_gds3732	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.91821
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5934
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4617
BRD-K57084585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82295
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45056
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62336
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21654
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07164
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.7103
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0042
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86914375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16929
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42391
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BFTC905	CCLE Cell Line Gene CNV Profiles	1.0	1.36251
ARID3A	ENCODE Transcription Factor Targets	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246204
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5964
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.197742
endosome	GO Cellular Component Annotations 2015	1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35029
ELF1	ENCODE Transcription Factor Targets	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07254
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60799
JE-61-EQ70_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22818
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92570288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52034
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2104
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.902676
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.88679
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.725977
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18428
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27482
PMC12255818-41467_2025_61448_MOESM1_ESM.pdf-64-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85162983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45472
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24001
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051097
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52089
KCNN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057283
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2126
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anchoring junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.4612
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
HPGDS-In1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08241
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04803
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6671
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	2.82335
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36023
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.2904
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00084
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04275
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
SREBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917108
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
region	GeneRIF Biological Term Annotations	1.0	null
NOTCH1-21737748-TLL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
L363	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91343
PPARG-19300518-3T3-L1 preadipocyte cells-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20194
IA-LM	GDSC Cell Line Gene Expression Profiles	1.0	1.68865
SP2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-1326-SM-4BOO1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05535
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916304
GSE164463_3_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49833
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
adhesion	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6034
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.59209
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.17214
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.818057
NOTCH1	ChEA Transcription Factor Targets	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55035
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916304
UMRC6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47574
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06081
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63672
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80240487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22398
RGS18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00642083
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47437
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829147
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10037
induce	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29055
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12775
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2752
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849977
9426_TUBGCP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.885727
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.59901
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58329
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34793
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49453
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12486367-Supplementary_Data2.pdf-168-NFYC_NFYC	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.649225
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.09884
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EG-06A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19015
Basal ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
CA-96-UO48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239066
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23836
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05495
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19036130-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0485
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.976787
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10994
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13648
hsa-miR-92a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.88648
16728581-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12017
BRD-K23461342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90015
BRD-A07214340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14609
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428687
ERR2 (ESRRB)	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K07501194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81136
GTEX-PWN1-0726-SM-48TDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997118
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39477
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03465
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7211
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JK-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885009
Liver Diseases	CTD Gene-Disease Associations	1.0	1.01324
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50396
BRD-K60188481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14028
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52269
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.08931
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0867
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938313
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865236
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11321995-41556_2024_1460_MOESM2_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Unique_genes_with_exons_significantly_correlated_with_OTX2_expression_in_Group_3_and_Group_4_MB_tumors_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5886-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96733881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20774
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16048
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
ZR-75-30	GDSC Cell Line Gene Expression Profiles	1.0	2.1122
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13141
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21381
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.006292
GSE199606_6_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01042
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21242
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13111
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3027
POLR3A_01_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59282
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79324911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06335
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3113
MCF7_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125071
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84743
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42043
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HJ-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17461
GTEX-XUJ4-1126-SM-4BOPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31538
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0426-SM-4LVM7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70157
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26513
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32782
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1892
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.3374
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8388
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.43383
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.128596
CRCGN013_HEPG2_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02456
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826048
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.67501
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218906
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR5A2_01_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63781
SP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76733
E2F4	ChEA Transcription Factor Targets	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214928
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.978063
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TE-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6008
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836352
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	1.0	2.09209
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06046
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
mcf7	HPA Cell Line Gene Expression Profiles	1.0	2.6109
BRD-K10133810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45725
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13986
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SARS-CoV MA15_Day4-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04851
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0301
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08347
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953717
BRD-K25933460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15207
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49366
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64568
BRD-K79908599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29124
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422202
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840726
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC11303399-41398_2024_3044_MOESM1_ESM.pdf-7-CENPA_CENPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30525
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17806
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26191
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938524
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903913
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135778
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cterminal	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.08502
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111102,GSE111105_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34815008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24327
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946718
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956839
BRD-K57323824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12412
BRD-K91923964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20831
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257316
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01138
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0989
BRD-K99485242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2716
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10634
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_4_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07934
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04637
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12671
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980266
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03716
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897271
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62231
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arecoline-1303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52072
naringin-2425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Apical ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04284
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4325	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54141
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7320752__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.38469
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848044
Perturb_11744_KO_Mek2_SRP321493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.79699
RPMI8402	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1926
rna	GeneRIF Biological Term Annotations	1.0	null
cell-substrate adherens junction	GO Cellular Component Annotations 2015	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21151
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.87514
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29668
BRD-K55160477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0202
LN18_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.73712
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.519
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16473
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59542
BRD-K66675422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24083
CE-37-XI06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275621
22RV1	DepMap CRISPR Gene Dependency	1.0	20.1724
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14107
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31692
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56829
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28746174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25389
BRD-K80535598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16449
AA-67-TF79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28357
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
demonstrates	GeneRIF Biological Term Annotations	1.0	null
GSE112860_5_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839902
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898646
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38589
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38204
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832348
GTEX-OHPK-2326-SM-3MJH2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25137
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02345
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74292
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2285
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A11154023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22155
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26354
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11848
BRD-K07567566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80466
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26202
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280219
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10417
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02233
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.853714
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929678
MAGI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699067
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925188
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MC116	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10617
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856694
CRCGN014_HEPG2_3H:B05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10935
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76983
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2583
NLRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658511
JUND	ENCODE Transcription Factor Targets	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6211
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.41561
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35329
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157904_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.195183
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17806
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0226-SM-4KL1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920686
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5374
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1437
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13782
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0129
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07583
PMC3607232-mmc3.xlsx-b_RUNX1_SEM_MLLC_H3K4Me3-x_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventral lateral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04466
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4092
Lung adenocarcinoma_LUAD_TCGA-80-5608-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_3_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399991
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18738
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.734058
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8687
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942464
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18428
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06929
hsa-miR-512-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K62758843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19967
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22907
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.9266
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84026
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32632
JUN	ENCODE Transcription Factor Targets	1.0	null
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19742
BRD-K68347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40981
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99679
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.424
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GM2345	BioGPS Cell Line Gene Expression Profiles	1.0	1.24822
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06666
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.49602
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34001
BRD-K17753780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05868
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28288
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910108
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873678
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GT-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596124
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06081
BRD-K06685815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74209
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39402
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMY1	DepMap CRISPR Gene Dependency	1.0	4.64773
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31561
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824902
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AM966	DeepCoverMOA Drug Mechanisms of Action	1.0	0.54
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84259
BRD-K54862370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17912
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37192
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836352
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.42349
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.63096
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514996
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896142
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02556
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03785
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.966193
A549_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143529
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20873
SW1417_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.13136
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.945856
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84636
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03002
BRD-K74329400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05616
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95432
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859102
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
adherens junction	GO Cellular Component Annotations 2015	1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-1.07799
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.25928
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41305193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33095
SP2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6326
PMC6293073-LSA-2018-00153_TableS3.xlsx-B_KD_Tr_2_genes-155_genes_upregulated_upon_knockdown_of_Tr_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.91296
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45984
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13734
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05436
KIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03756
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95455263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73911
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14902
multiple	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07782
BRD-K66145389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12524
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33999
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05446
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.904576
STOCK1N-28457-6906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	1.0	1.73508
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27307
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.831
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20165
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00116
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16322
Cilengitide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.89
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52534
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.78662
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05627
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.011
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45972
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24726
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29724
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20949
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14909
domperidone-2655	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.38411
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4316
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10416
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50746465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04275
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04392
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03739
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876341
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06405
TGFB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494812
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836352
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41971
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18227
BRD-K98239824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07535
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.316
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_261_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85841
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5432-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67543
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNUC5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36629
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55284
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.29994
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26599
Glufosinate	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.860831
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75772626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03304
HEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62273
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13502
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20604
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98156994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29061
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95409124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07737
BRD-K60543885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69296
Perturb_12631_KD_SIRT5_SRP311327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02302
PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57553
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32197
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46874
CCLFPEDS0001T	DepMap CRISPR Gene Dependency	1.0	2.0352
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K67337799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0374
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.472682
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18768393-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873252
GJD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00482867
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.804
cell-substrate junction	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02362
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30075
CREB1	ENCODE Transcription Factor Targets	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
azacitidine-4010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESRRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902007
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
19204204-SupplementaryTable5	GeneSigDB Published Gene Signatures	1.0	null
BRD-K80807286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44867
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72185
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-1126-SM-4LVN1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05311
RL	GDSC Cell Line Gene Expression Profiles	-1.0	-2.27211
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838452
GSE160373_8_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889568
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56852
NCIH146_LUNG	CCLE Cell Line Proteomics	1.0	2.76072
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836761
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21326
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79315
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	0.856886
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10813
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03383
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8041
invadopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.703507
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94411351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18092
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DU-145	GDSC Cell Line Gene Expression Profiles	1.0	1.44039
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282707
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229123
Perturb_6046_KD_PES1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06507315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72539
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21324
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14546
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21572
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.869633
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10314
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10037
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10063
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40457
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3848
carcinine-4809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25165
ESRRA	ENCODE Transcription Factor Targets	1.0	null
Perturb_16536_KO_Ptger4_SRP238348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34384
BRD-K21416096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69409
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26838
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14415
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
8-azaguanine-1833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27621887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69522
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3285
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.103
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.761702
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851843
BRD-K71604365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1846
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.995218
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.10108
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53355
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.14543
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72261
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831033
YB-83-AS93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254544
MEL270	DepMap CRISPR Gene Dependency	1.0	2.23465
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17485
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00624
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64722080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38971
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868336
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45488
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51128
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.88575
EGFR_drugactivation_19_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.48777
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25021
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Ca-Ski	GDSC Cell Line Gene Expression Profiles	1.0	1.81228
SCLY	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6451017-41598_2019_42107_MOESM11_ESM.xlsx-all_PHOX2B_as_effector_lincRNAs-mRNA_genes_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-565-ZFP42_ZFP42	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03026
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS2_2019_Affy_IDs_SignalsQN-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.62867
BRD-K19046167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16148
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342405
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0222
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22308901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20915
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916304
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16252
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-1080 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29269
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ADARB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0071541
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5741
PC-87-OG75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440139
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K27248268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22557
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06081
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13716
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.17897
BRD-K56120807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92719
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20298
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00929
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.729755
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93873
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415138
CRCGN013_HEPG2_24H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07096
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06409
RB1_KD_GSE50532_592_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K20470077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55546
BRD-K56107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46937
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49551
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38922
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.867353
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04405
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85404
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1040_C1ORF131_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.11104
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08362
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831508
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02145
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0728
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40148
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE6	CCLE Cell Line Gene CNV Profiles	1.0	2.03473
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.14192
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05193
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.048
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07226
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60601
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01644
Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6371
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02503
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isoetarine-5812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481035
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15441
GTEX-UPJH-0726-SM-4IHJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07067
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93817456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01104
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03507
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07855097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78303
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K52062350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2013
CA-16-ZL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210152
5587_NEDD8-MDP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.682489
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50832
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4718	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20674
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06598
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32475
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51344
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20478
BRD-K04251837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23382
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.568
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2176
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142630_0_v_2_hiltonol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08119
PMC11143964-jciinsight-9-161356-s009.pdf-13-SMAD5_SMAD5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837791
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12107412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33017
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21528
Perturb_4876_KD_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.2429
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.424
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919843
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5594
GTEX-WFG7-0626-SM-4LMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824748
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.46708
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43524
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986225
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.844986
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A695-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.011
BRD-K29392278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17312
BRD-K16670438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06984
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	2.09911
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80999
BRD-K78311779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93265
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06133
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
9179_TOPBP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.540241
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OC-23-QX66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262117
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
NALM-6	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85203
8666_TAF5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.617813
GTEX-RWS6-1726-SM-47JXP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877481
MCF7_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016362
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28156
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11898
BRD-K56261053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71775
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12098
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85942
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957239
CPC-N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93945
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49607
ELK1	ENCODE Transcription Factor Targets	1.0	null
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100492_TCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16018
STK33_knockdown_50_GSE15151	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.80778
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30686
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37285
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05061
hsa-miR-367	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10284009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00383
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.781598
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200694
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34381
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.85387
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_AICAR_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215751
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14
BRD-K86232198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19215
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53907
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
MCF7_Veliparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167132
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33131
POU5F1-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210467
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22569
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899163
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K96023136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92049
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46431
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88N-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4348
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19107
anchoring junction	GO Cellular Component Annotations 2015	1.0	null
17483317-TableS5	GeneSigDB Published Gene Signatures	1.0	null
b104	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309879
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01189
MELJUSO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71651
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19255
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	2.38093
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell-substrate junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MCF7_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014435
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75649446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65811
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903788
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3312
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.56992
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69467
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51515697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65487
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14965
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941763
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39291
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987356
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65104
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.49895
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25721
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11992
Infertility, Female	CTD Gene-Disease Associations	1.0	1.19802
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0172
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16607
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.868123
PMC7220941-41598_2020_64431_MOESM2_ESM.xlsx-WS1_2019_Affy_IDs_RA-STvsOA-ST-Unnamed_2_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	1.72587
16166195-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K67229323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39694
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4116
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2838
STAT1	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59946
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17166
CCDC62	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659111
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12679
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44778
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKG-IIIa	GDSC Cell Line Gene Expression Profiles	1.0	1.56563
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11258
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4818-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9553
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.35618
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878057
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878728
cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15637
PC14	CCLE Cell Line Gene Expression Profiles	1.0	1.57734
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.42721
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07117
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K41389177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38702
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470793
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1722
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06849
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43314
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.443
BRD-K51160592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.552
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57791
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839837
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49169
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0785
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928293
AB-00-IL62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.880623
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.609704
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884959
20860821-TableS5	GeneSigDB Published Gene Signatures	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-80-GK24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204654
molecular_function	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0242
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225367
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09336
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414797
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13631
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03379
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09066
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62659610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44739
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CCDC50	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594948
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12646
MTF2	ChEA Transcription Factor Targets	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20165
FB-32-TL51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211858
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05009
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09009
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.47518
hsa-miR-522	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OSC-19	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
melanoma; skin neoplasms	GAD Gene-Disease Associations	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
17952122-GeneList	GeneSigDB Published Gene Signatures	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72703
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0818
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2041
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1809
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDC7_knockdown_109_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7839
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458889
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966156
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953256
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.672
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60886324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41493
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17255
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95672449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35046
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60597
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32546
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21608
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.086
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	6.51635
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pentamidine (isethionate)_NCI-H2347	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00390393
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96129
GSE172201_1_v_0_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932458
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05992
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03362
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95707
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75422
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833522
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988451
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ability	GeneRIF Biological Term Annotations	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74202
cell-substrate junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.925577
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.183063
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840112
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40145790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16936
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41595
CD1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0071133
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36526
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23869
BRD-K42232544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51594
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10328
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18118
BRD-K94573433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84808
PBX3	ENCODE Transcription Factor Targets	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.49457
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77047
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60198
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910157
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4018
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979103
GSE166317_2_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN010_HEPG2_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29362
POR_KO_GDS1678_762_mouse_Jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311496
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSD17B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14441
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44365
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08075
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.24496
BRD-K41396351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6272
PSG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00911781
BRD-K82538319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10616
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20371
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34941
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.804
2633_EN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.849339
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1803
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.803
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29125
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12017
BRD-K04928505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44104
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901495
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939998
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972245
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07271
MPC-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35346
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.72288
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8305C_THYROID	CCLE Cell Line Proteomics	1.0	2.40753
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLVL	DepMap CRISPR Gene Dependency	1.0	3.64094
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273346
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11908
BRD-K76616863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78522
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914889
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20165
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5126
GTEX-WFON-1026-SM-4LVMD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79065
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230368
KYSE-270	GDSC Cell Line Gene Expression Profiles	1.0	1.69252
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0485
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40101
BRD-K71778797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18145
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19741
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01633
PMC10828394-41698_2024_509_MOESM1_ESM.pdf-125-ZBTB45_ZBTB45	Rummagene Transcription Factor Associations 2026	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2021
E2F4	ENCODE Transcription Factor Targets	1.0	null
SNU719_STOMACH	CCLE Cell Line Proteomics	1.0	7.83435
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00042
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14664
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0933
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98695520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64281
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYMS	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-287-CREBZF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-28-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K88504000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08366
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, frontal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16307
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.02933
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918634
T3M10	CCLE Cell Line Gene Expression Profiles	1.0	1.53165
BRD-K91696235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30082
MXI1	ENCODE Transcription Factor Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_1_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.49575
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K20722478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45777
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923022
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.47001
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
In situ melanoma of skin_Epidermis_GSE4587	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.12099
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29937
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855027
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ATF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K04399953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00455
BRD-K79494396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25499
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.424
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
calcium pantothenate-1311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20634
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.872061
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	0.874645
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC106	DepMap CRISPR Gene Dependency	1.0	2.4912
HEC59	DepMap CRISPR Gene Dependency	1.0	3.04119
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59946
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90625171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14203
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
MOTN1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11846
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47116
mefenamic acid-1863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NS-398-6911	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04006
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52093
16484322-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57568
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43611
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76704
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04008
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16112
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.4126
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.99961
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162563
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889161
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cingulate gyrus, frontal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963057
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
allantoin-1842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832766
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12709
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.94559
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.47122
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15374
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28166
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33393
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87389
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.12259
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C2	ENCODE Transcription Factor Targets	1.0	null
1-cell stage cell (Blastomere)_Embryo_Human	CellMarker Gene-Cell Type Associations	1.0	null
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08168
BRD-K81217407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94484
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCB000039-7510	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2838
HH	GDSC Cell Line Gene Expression Profiles	-1.0	-2.34856
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
LOX-1_OE_GDS4262_433_human_HAECT - aortic endothelial cell line - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27321
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imipramine-1849	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88603
CRCGN017_MCF10A.WT.HP_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5671
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.36
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12839
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399413
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19841744-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16113
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37634
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52278
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891993
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548g	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30391
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06705
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF15_KO_GDS4780_509_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DFCI024	CCLE Cell Line Gene Expression Profiles	-1.0	-2.84583
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22111
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93481
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26803
1340_CCP110_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.610784
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.64958
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KPL1	CCLE Cell Line Gene Expression Profiles	1.0	2.02011
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.68588
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928919
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69348766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48866
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35133
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01467
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875631
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23561
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6034
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84148
Thyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
CRCGN016_MCF10A.TP53.M_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07861
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73062
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25894
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.49262
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830582
KDM5A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49401
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
Bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MB-72-YK93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424876
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854696
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A718-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-11A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41488
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33845
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15875
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874051
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17441
BRD-K11696817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05924
GTEX-XBED-2326-SM-47JYR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888953
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8418
3776_HIST1H4A_ENST00000359907.3	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.67216
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38005
BRD-K13681383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94123
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6496
HS172T	CCLE Cell Line Gene Expression Profiles	1.0	2.21018
BRD-K96737756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56961
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11918
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52765
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46456
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18342
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59191
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF_01_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.95974
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20362
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26196
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0987
ROS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89273
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208698
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05923
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504081
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5501
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44426
Perturb_12035_KO_Ccr2_SRP247656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.69978
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1021
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.891818
BRD-K87261428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17684
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.47443
DB-01-BR68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261815
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19365
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86435
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46907
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920547
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02965
BRD-K91854399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0097
BRD-K87465930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68086
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02415
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55459
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937241
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.910402
ZNF384	ENCODE Transcription Factor Targets	1.0	null
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4297
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAN2	DepMap CRISPR Gene Dependency	1.0	2.62979
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209502
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27202
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38948
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832766
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53404
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.15606
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07912
KMS34	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32663
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47945
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_253_GSE30651	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.25238
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48379
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5846
BRD-K39291909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28468
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361084
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31629
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11318
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.74586
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49289
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19939
K029AX_SKIN	CCLE Cell Line Proteomics	1.0	2.06082
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919311
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962064
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.077
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5123
organelle	GO Cellular Component Annotations 2015	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.68174
BRD-K34277236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0966
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03008
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.64007
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052347
vesicle	GO Cellular Component Annotations 2015	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
A3-KAW	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55233
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10792
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2795
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980266
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10581
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99113
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15876355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13336
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916304
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	2.38717
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13822
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93260425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61625
BRD-K77108738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32842
NFYA	ENCODE Transcription Factor Targets	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874368
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05001
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88338
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911781
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07564
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427325
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14014
BRD-K81099637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03397
diphenylpyraline-4299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851843
BRD-K47108422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50208
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20139
IRF1	ENCODE Transcription Factor Targets	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897823
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46246
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22031
BRD-K49507197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0795
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33824
noscapine-5851	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7997-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31521981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10785
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51315
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32422
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73897
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987375
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.01437
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00091
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69159
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292112
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_2_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40760168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1491
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.08757
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922649
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.69732
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35601
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5972
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.90714
endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19652287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94601
hsa-miR-4280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K56041932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00311
CREB1	ChEA Transcription Factor Targets	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940989
BRD-K48782834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09509
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19662956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26718
sulfathiazole-4769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K86285108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70821
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147366_1_v_5_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57014767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16165
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23648
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.93459
GTEX-S341-0826-SM-4AD73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991288
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054634
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18802
Perturb_7111_KO_Atf4_SRP344236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.17756
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93464
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35311
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26725
BRD-K53893978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09739
GSE210476_11_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_5521_KD_Apoa4_SRP393880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.81626
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369428
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66302
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07041
MCF7_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0059739
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64073
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-S341-1126-SM-4AD6T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839331
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.747515
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32107
SUZ12	ENCODE Transcription Factor Targets	1.0	null
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05626
Perturb_16605_KO_Bend2_SRP357909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.35345
CRCGN010_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08321
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.667026
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34871
canadine-4020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89216747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88312
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5674
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
key	GeneRIF Biological Term Annotations	1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K46985581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49959
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A67787745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4939
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.531
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0394
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02509
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967407
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96165
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23783
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864244
BRD-K52468958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74269
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26357
H-89-6921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24771
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30391
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.48893
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32821
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4191
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15556
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8861
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23739
PMC9691391-7945884.f3.pdf-82-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830965
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997595
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67711
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-175-VII	GDSC Cell Line Gene Expression Profiles	1.0	2.16163
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61560971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4652
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88484
BT474	CCLE Cell Line Gene Expression Profiles	1.0	1.74938
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1534
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.012
GSE249544,GSE249637_9_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45134469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69725
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHA-00665752-6578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.947442
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862994
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11184
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7684
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.5778
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.97293
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77065
DNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14283
BRD-K67022703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89795
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48608
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02302
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.53916
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22451
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4165-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Membrane attack complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.369
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25165
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23226
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91182
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362_OVARY	CCLE Cell Line Proteomics	1.0	5.32657
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842254
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26492
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4294
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.844
everolimus_mus musculus_gpl6885_gse37129	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57419
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K90231936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37074
Follicular adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61947
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390221
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4949
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860131
Lobular carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910221
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.584
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266991
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398531
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08266
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
MCF7_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141838
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19772
ZNF600	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97843
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.71064
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.980283
BRD-K47510632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46243
BRD-K93442068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26872
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40856
BRD-K66735533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02249
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878728
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09602
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371477
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824243
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	1.37063
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896397
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A07944983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25576
NCIH522_LUNG	CCLE Cell Line Proteomics	1.0	3.9313
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70983
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-363	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405839
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82725
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36287
hsa-miR-32	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.09807
BRD-K46082763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04983
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.973
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.18355
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960891
BRD-K18352607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.133
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413209
BRD-K46001734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20964
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42455
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.835816
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13039
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
E2F1	ENCODE Transcription Factor Targets	1.0	null
focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.741416
BRD-K70844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25766
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.24989
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03556
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3391
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293106
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1001
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904983
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11893
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07787
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05443
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell-substrate adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.737813
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42343
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70692
Hypertrophy	CTD Gene-Disease Associations	1.0	1.56288
BRD-A23980907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19055
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25514
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621407
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93305
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03068
GCG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051385
PMC12123029-41598_2025_3625_MOESM1_ESM.pdf-40-SREBF1_SREBF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38631
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36119
BRD-K05269173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51058
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.8341
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987375
adherens junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89459607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26396
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20165
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.01547
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
QB-99-OU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357424
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840531
BRD-K89065802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06237
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.20661
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464912
Lung adenocarcinoma_LUAD_TCGA-55-8087-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28567
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
u2197	HPA Cell Line Gene Expression Profiles	1.0	0.92335
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0644
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214741
POU5F1	ChEA Transcription Factor Targets	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166319
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.2432
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4376
BRD-A78125048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77883
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.032
isoflupredone-1832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4407
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.28425
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PC14	CCLE Cell Line Gene CNV Profiles	1.0	2.27528
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04607
GTEX-XV7Q-1226-SM-4BRVT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14003
BRD-K09168812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11102
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10868
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89484
sirolimus_rattus norvegicus_gpl6247_gse35048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ciclosporin-1331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K21119095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18328
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974783
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33713
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04839
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17018
CC-93-RP38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.774672
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.221
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.12106
NB1643	DepMap CRISPR Gene Dependency	1.0	9.53074
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1211
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928577
regulator	GeneRIF Biological Term Annotations	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02233
hsa-miR-92b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K85456301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01624
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81492
GTEX-UJMC-1026-SM-4IHKN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01153
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1772
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844348
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57228
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4731-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5770158-elife-31706-supp3.xls-ISL1_target_regions-Nearest_gene_2_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.46891
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17715
EM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49356
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62032
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0347
BRD-A86415025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3457
LY6G6F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587703
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21135
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.22561
puromycin-6711	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222494
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	1.40678
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4116
BRD-K87264606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48257
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MDAMB231_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920568
FA-92-JL46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440397
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40708
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20507
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56316
Fatty Liver	CTD Gene-Disease Associations	1.0	1.20881
BRD-K83527041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00082
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03866
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14719962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27376
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.88615
kidney	HPA Tissue Protein Expression Profiles	1.0	0.888546
hsa-miR-25	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97706
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833676
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.865253
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833804
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03742
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60212
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31181
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.937317
CRCGN009_HEPG2_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04445
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35406
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35262
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54702
SKNDZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39173
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.18618
GTEx SmallIntestine 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.84606
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-325	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.15603
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81815
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
benperidol-4781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52428486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02036
NCIH1437	CCLE Cell Line Gene CNV Profiles	1.0	1.66156
MRK-nu-1	GDSC Cell Line Gene Expression Profiles	1.0	2.16568
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10899
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	1.0	1.77083
BRD-K91712163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81325
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68696
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70029
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55052
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4079
zoxazolamine-1270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.578235
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895635
18535662-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91937
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.1838
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.917031
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21242
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0826-SM-48U1G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14042
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87776049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20652
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863533
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883459
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842763
HCFC1	ENCODE Transcription Factor Targets	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29382
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0182
DA-17-YW85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206983
hsa-miR-411	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34317
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19177
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83274
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.29908
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07996
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187927
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.637
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840107
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.10244
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54324
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17373
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34149
trichostatin A-5017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98534
SMARCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531623
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907235
Perturb_4848_KD_NKX25_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.91835
fas	GeneRIF Biological Term Annotations	1.0	null
Dorsal lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904531
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A32128687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03355
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.84348
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21242
BRD-K13275816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42689
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.686
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18227
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.94195
FOS_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990153
CREBBP	ENCODE Transcription Factor Targets	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53354
BRD-K25596713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26791
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66083
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18395
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.282
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915689
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07774
DE-99-OT37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20994
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17919
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	3.56237
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
BRD-K86938753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46734
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53263
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnocellular diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15203
WM793_SKIN	CCLE Cell Line Proteomics	1.0	2.422
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.40923
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271432
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76257
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04587
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18581
BRD-K01045229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38031
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.44876
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938331
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04697
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-encode-consensu_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07404
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30075
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0621
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894651
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K94657740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46953
BRD-K17410712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3195
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
superficial stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26482
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65913
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594393
CCNT2	ENCODE Transcription Factor Targets	1.0	null
BRD-K98578493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09333
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17803
spreading	GeneRIF Biological Term Annotations	1.0	null
BRD-K99210277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16132
GSE200320_1_v_0_mfge8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.03342
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86892
LU-135	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65929
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20239
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934103
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999471
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3305
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12194
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961672
AC-97-KP88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25183
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
1,4-DHNA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.41091
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6281
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39295
Perturb_6035_KD_MBD3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.96071
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.606066
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94956
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.63437
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12017
MCF7_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109021
GSE160817_0_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.568
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922111
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09702
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_37_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5654
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19993
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYB5D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00983145
BRD-K55392659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04777
hsa-miR-4640-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74625
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11282
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845812
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876474
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50941200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06914
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.46685
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843879
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.04027
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836352
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05453
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33348
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.13559
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09095
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11187
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FD-15-HD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341541
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14853757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6248
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43413
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50381
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18525
COV644	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93736
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842661
KIRREL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652602
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83119
BRD-K87593103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92122
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Perturb_3924_KD_VPS37B/VPS37C_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37783
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.07576
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1223
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JZ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50008138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40715
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.422
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878057
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25894
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838714
Neointima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
AF-10-QK79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288122
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23301
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21532
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03339
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58876832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99809
BRD-K87901124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78747
BRD-A03121430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41686
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56911
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59763
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-97-KP88_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236658
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Potassium Dichromate	CTD Gene-Chemical Interactions	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06244
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01456
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01267
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.725705
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38403252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02001
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981276
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28697
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
10400_ZNF497_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.775702
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20611
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78608
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9819
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825852
BRD-K85951787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00239
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1456
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10641
Zinc finger, FYVE-related	InterPro Predicted Protein Domain Annotations	1.0	null
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03984
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00235
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09429
TE6	CCLE Cell Line Gene Expression Profiles	1.0	1.58624
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02097
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39873
JL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37191
PEBP1_KO_GDS4334_617_mouse_Pancreatic beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
11090_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.590693
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15717
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2107
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.145
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03862
BRD-K29898553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73976
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6166
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27526
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926974
CORL47_LUNG	CCLE Cell Line Proteomics	1.0	6.2582
GTEx Brain 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	6.3368
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846888
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936692
Perturb_11770_KO_Stat3_SRP128652	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.33334
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
CRCGN008_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63665
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00823
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20421
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926992
HEK 293T	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.947366
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53453
CE-37-XI06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258504
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metoclopramide-2353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHEK2_knockdown_84_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.16573
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987491
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245022
TE-6	GDSC Cell Line Gene Expression Profiles	1.0	1.85806
PPIP5K2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472783
mifepristone_mus musculus_gpl6887_gse39270	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204087
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.5389
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952781
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24159
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875956
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22087
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02026
Pancreatic adenocarcinoma_PAAD_TCGA-YH-A8SY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0018
BRD-K39499927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44763
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4579
MCF7_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126513
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926214
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23931
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10037
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11812
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41351
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4773
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02088
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92034
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE5370	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.22898
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216026
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80181
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96953
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	2.10949
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865405
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43726
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935671
GTEX-PLZ5-0826-SM-3P5ZW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98507
CEBPZ	ENCODE Transcription Factor Targets	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.890298
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74503
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26785
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.804
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24042
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00225
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27053
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47283018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1754
BRD-K53540914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34063
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO320	DepMap CRISPR Gene Dependency	1.0	5.11882
Perturb_5351_KO_Dux_SRP201141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.26985
migration	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20185935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85611
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40056
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01343
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00389763
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05953
CRCGN010_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19889
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58416
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.61953
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.747353
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03545
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28346
atovaquone-4786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Melanoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56595246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35879
BRD-K99690279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12446
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20971
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BY-01A-31R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.22488
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899814
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3196
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60454
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23063
WT1	ChEA Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3956
Weight Loss	CTD Gene-Disease Associations	1.0	1.36961
S117	DepMap CRISPR Gene Dependency	1.0	6.26967
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.74989
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14812927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01332
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.67655
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938762
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10462
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984755
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02935
rosiglitazone_mus musculus_gpl1261_diabetes_gds4036	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.297
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01292
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.93098
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PFEIFFER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51632
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03689
BRD-A16760970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19509
10751_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.546262
4951_MED28_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16914
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45418
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58224
LU65_LUNG	CCLE Cell Line Proteomics	1.0	2.422
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.924786
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G6-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.58473
metoprolol-2543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53145
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.4331
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01953
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35442564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49803
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.893
HMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.24118
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K25470159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38936
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.937752
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254833
BRD-K44921931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32111
MHH-ES-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.86139
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910816
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32697
BRD-K48035513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22917
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911077
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5880-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83873
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26035
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26682
Perturb_15901_KD_Jun_SRP361315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.35981
BD-96-HO33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.489004
ZNF263	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-1526-SM-4LMIG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10214
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70532227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02191
BRD-K06550516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3366
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0347
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10074-G5	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223174
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74896
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Pirarubicin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149276
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907566
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17196
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918764
BRD-A23193246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25284
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163052,GSE163198_2_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44518
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3163
Aiolos_NULL MUTATION_GDS3473_572_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K58336011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.152
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65776
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00624
BRD-K53343197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63683
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10788
valproic acid-1647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860001
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09579
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66494
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836358
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58446
BRD-K34977825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21328
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29353
BRD-K07160568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20276
BRD-K68605096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21089
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34044
NELFE	ENCODE Transcription Factor Targets	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935216
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85351
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15575
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47697
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28873
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01473
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.126
TYKNU_OVARY	CCLE Cell Line Proteomics	1.0	2.15356
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223311
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10769
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08071
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SHP77	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89033
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN015_MCF10A_48H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34477
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472434
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881966
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.914307
Lung Injury	CTD Gene-Disease Associations	1.0	1.26452
MCF7_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139963
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45383
Perturb_17196_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.4836
Occupational Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37754
17683608-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78572
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.10521
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90558
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04461
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12017
BRD-K88362336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22506
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1936
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54968
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22608
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19993
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243506
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985307
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-11A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12008
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87213231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24081
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59501
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883141
BRD-K17285268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81754
BRD-K99650219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72488
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEx Muscle 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	14.0333
BRD-K60837711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13735
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997988
BRD-K73364700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40829
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr14_103554117_T_C_b38	GTEx eQTL 2025	1.0	1.16314
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26319
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33215
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.4138
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F6_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887047
CCND1	ChEA Transcription Factor Targets	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341683
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56658444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29326
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2845
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953711
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ACC3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.19047
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881995
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855716
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875457
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.829909
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23427
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.8559
HMGN3	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6085
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.519
CRCGN015_MCF10A.TP53.M_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0695
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
valproic acid-6173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46722
CRCGN011_HEPG2_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12475
TEN	CCLE Cell Line Gene Expression Profiles	1.0	2.57122
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359553
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216206
BRD-K60216304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44181
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QS-0726-SM-3NMCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06332
RPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40852
GTEX-PLZ6-0326-SM-3P61J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3153
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901826
BRD-K61439332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35656
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76108
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26207
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18941
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142556
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37596
Learning Disorders	CTD Gene-Disease Associations	1.0	1.0894
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.105
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44925
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08135
RCOR1	ENCODE Transcription Factor Targets	1.0	null
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
regulating	GeneRIF Biological Term Annotations	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864388
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968326
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01462
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.004
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00902
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56213
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03202
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.004
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
BRD-K43284834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22652
u698	HPA Cell Line Gene Expression Profiles	-1.0	-1.04604
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16154498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30048
GSE250089_0_v_3_epcam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08183
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.54741
BRD-K75625428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27668
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K97241181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05754
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09729
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
NOTCH1-21737748-TLL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975384
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.35825
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF15_Deficiency_GDS2687_649_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10554
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16542
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
frontal operculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.841749
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38881
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cd4.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.83722
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77811
GIMAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00466475
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17743
BRD-K27578003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14314
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
player	GeneRIF Biological Term Annotations	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2336
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.95093
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315401
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845594
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55105
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44648
16484322-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169812
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76829357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08124
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
4-Aminobenzohydrazide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21365