association	dataset	threshold value	standardized value
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-0.906336
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928391
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6642
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03069
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.931127
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70996
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H-1152	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.56915
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10407
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910967
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843676
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82513
G361	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12444
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85053
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS19BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08688
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207203
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0404
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931381
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913666
ZBTB33_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.29323
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25559
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998893
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.90387
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4321
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85933
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46289
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55925
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38736
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872944
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9135
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Disease Associations	1.0	0.618434
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66221
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951548
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917908
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32662
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3381
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0273
3447_GNL3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.843274
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02861
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958858
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04855
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853516
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49983
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922601
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.923
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0024
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8893
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239651_1_v_0_ispinesib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20933
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942199
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20575
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872582
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1083
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14835
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02174
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.54863
ATF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14493
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-0726-SM-4DXT5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24423
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59641
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4869-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19834
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Quinidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
Lung squamous cell carcinoma_LUSC_TCGA-22-5473-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93094
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5745
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33127
ST6GAL1_Deficiency_GDS3151_608_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38093
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.255557
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860737
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73127
SNU1214	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5632
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05463
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8691
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08003
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966367
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9286
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927115
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831723
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19581
PMC12323057-13148_2025_1945_MOESM2_ESM.xlsx-17-Supplementary_Table_17_Overview_of_number_of_targets_genes_shared_with_THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
CDK13	Kinase Library Serine Threonine Kinome Atlas	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38985
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88489
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.0277
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77727
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28582
SP4	ENCODE Transcription Factor Targets	1.0	null
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14056
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	2.41982
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.11068
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Asarone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.84
ASPC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01912
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7881
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4078
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04525
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.59511
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51256
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	1.56748
TERF2IP	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.707
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	2.65688
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860186
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964841
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10653_ZNF80_ENST00000482457.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.532371
GSE190947_2_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08595
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72877
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896933
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09158
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47349
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6338
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.60182
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Undecanoic acid	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41071
LY334370	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898679
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11048
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10804
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.09713
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938006
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.6581
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43779
SUPM2	DepMap CRISPR Gene Dependency	1.0	2.08472
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32267
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.51252
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212495
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09461
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59853
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.648
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56412
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910204
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909814
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02015
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57358
Golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.838432
FOSL2	ENCODE Transcription Factor Targets	1.0	null
UMNSAH/DF-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
HUH6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.585
MYBL2	ENCODE Transcription Factor Targets	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61387
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85053
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microcephaly	MGI Mouse Phenotype Associations 2023	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	2.12829
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.27001
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34547
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39565
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909814
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910059
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23771
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02788
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0597
HEPG2	DepMap CRISPR Gene Dependency	1.0	2.91279
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95396
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37337
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07995
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-0.947081
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88852
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.0939
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0414
RPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20653
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11354
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12355
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01883
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38086
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
9424_TUBG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.500187
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24331
TE6	DepMap CRISPR Gene Dependency	1.0	2.45338
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71307
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8429
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
176_AFG3L2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.534937
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09802
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1878
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856709
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845868
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22917
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51698
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2454
GATA2_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40002
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19448
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57682
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19224
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7S9-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941348
atrophy/degeneration affecting the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.525058
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.61587
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19472
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22134
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8183
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889995
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3581
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.34389
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05699
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873755
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902791
MYLA	DepMap CRISPR Gene Dependency	1.0	5.50744
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24836
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.00504
GATA1_G1E-ER4_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8508-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOGGUVW	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75995
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36385
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95175
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3122
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0369
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
GSE199204,GSE211619_4_v_5_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33504
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21673
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19124
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24811
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94261
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11714
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IM9	DepMap CRISPR Gene Dependency	1.0	2.11695
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20951
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896282
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.36519
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28524
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11074
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8326438__F10	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65824
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50493
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04228
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0723
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0046
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proton-transporting V-type ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00622
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.864309
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844343
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49278
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
127399	DepMap CRISPR Gene Dependency	1.0	3.58561
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45804
DOV13	DepMap CRISPR Gene Dependency	1.0	2.23668
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94308
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01518
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39703
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_0Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.68361
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	1.96875
PMC7575087-pgen.1009097.s009.xlsx-NOT_SW_induced_enriched_motifs-Central_TF_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84361
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3194
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40619
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21988
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946652
BEC	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43374
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11863
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86754
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	0.918564
GATA2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0008
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29517
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841297
EGR1	ChEA Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880382
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923396
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8457
SETDB1_KO_GSE40296_7_mouse_brain (telencephalon)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10828394-41698_2024_509_MOESM1_ESM.pdf-126-ZNF135_ZNF135	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_knockout_303_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.21483
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14381
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT1376	DepMap CRISPR Gene Dependency	1.0	6.39756
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901342
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07041
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863883
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878851
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834868
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27559
hsa-miR-4742-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.878059
NFIC	ENCODE Transcription Factor Targets	1.0	null
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07784
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDMYZ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45332
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896933
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07354
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GATA1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81356
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03953
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12286
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9404532-NIHMS1788564-supplement-Supplementary_Tables_1-8.xlsx-Supp_Table_6-MYC_UP_V1_DN_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00215
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75528
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05522
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14839
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959646
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20715
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31756
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58912
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925589
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944164
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM24_knockout_299_GSE19675	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.86332
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03297
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925863
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406035
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50092
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36021
adult ovary	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14198
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5657
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982979
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.868475
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33105
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.964718
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	3.07925
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43403
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96087
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.345
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12475
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.05636
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6612
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17796
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.9497
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90386
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11481
cation binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01874
hsa-miR-4668-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830573
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37553
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleoli	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.91646
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85053
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postaxial acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59902
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-THP-1_MLL-AF9_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Zinc finger, C2H2	InterPro Predicted Protein Domain Annotations	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973608
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961781
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92516
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947985
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-80-ZNF28_ZNF28	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84337
RELA	ENCODE Transcription Factor Targets	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878694
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2012
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	1.66265
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913094
ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47943
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4399
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26264
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1519
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60448
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18613
GSE107854_2_v_0_prmt5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47686
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12426
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975085
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256502
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407796
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.94359
MET_knockout_261_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67938
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907878
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06365
TCF12	ENCODE Transcription Factor Targets	1.0	null
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.69553
PMC9531837-pone.0269077.s012.xlsx-EWS-FLI1_ratio_5_p_value_0_05-Gene_name_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862163
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67803
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29211
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15481
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93169
Perturb_2519_KD_ZNF414_SRP269946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
A704	CCLE Cell Line Gene Expression Profiles	1.0	1.42419
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.02837
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.52465
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83254
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	3.16581
YY1	ChEA Transcription Factor Targets	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.993191
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224745
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95989
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0254
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855618
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47056
F5	CCLE Cell Line Gene Expression Profiles	1.0	1.62464
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05398
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36603
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.30946
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80671
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70488
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_7day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.8019
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.8359
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.884326
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05919
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17404
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873755
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01944
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.26933
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873755
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983674
Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31819
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70251
a431	HPA Cell Line Gene Expression Profiles	-1.0	-0.853759
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.14383
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04531
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24753
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8150-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3508
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929122
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998012
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43597
MKN45	DepMap CRISPR Gene Dependency	1.0	3.4321
RPMI7951_SKIN	CCLE Cell Line Proteomics	1.0	2.38103
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.42276
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5861
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924002
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00932
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38464
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7283
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252785
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877802
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93394
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48038
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252059
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20182
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19299
7657_SARS_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.23977
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06962
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0996
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.743371
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20869
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32177
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5273
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44287
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.71833
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47118
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33934
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975084
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149010_0_v_6_dars2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54325
SNU81	DepMap CRISPR Gene Dependency	1.0	2.09987
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902826
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9226
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09444
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0576
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19198
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68045
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03282
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03716
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51143
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07818
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.770648
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25043
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocycle biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18651
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78907
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24988
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210966
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74069
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873755
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Supplemental_Table_9_NEUROG3_bound_TFs_genes_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Rhodanine derivative38	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96715
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-2.62182
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17041
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984455
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11834
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884346
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962097
Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_12_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.12919
HOP62	DepMap CRISPR Gene Dependency	1.0	2.05055
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24193
PMC12130184-12276_2025_1441_MOESM5_ESM.pdf-8-ZNF688_ZNF688	Rummagene Transcription Factor Associations 2026	1.0	null
DC-45-WU45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279544
Arsenic	CTD Gene-Chemical Interactions	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880312
LN229_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	7.4685
ETS1	ENCODE Transcription Factor Targets	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.077289
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11425
PMC10809641-DataSheet3.pdf-432-ZNF37A_ZNF37A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12464728-HSR2-8-e71283-s008.pdf-353-ZNF335_ZNF335	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01282
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38476
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.22715
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32368
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925276
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5641
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1737
Prostate adenocarcinoma_PRAD_TCGA-G9-6343-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26741
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19769
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02979
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLR20	CCLE Cell Line Gene Expression Profiles	1.0	1.54782
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0142
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824155
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07257
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01618
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39584
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37654
hsa-miR-566	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.901341
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.264713
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7914
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.59043
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976381
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
IGF1R_knockdown_52_GSE16684	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.32532
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832662
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.98452
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95588
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8645
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217494
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19202
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834219
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
TE10_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.01549
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6163_GATD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515972
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834578
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94535
1346_CCT2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.72067
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52851
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89999
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.74116
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
u937	HPA Cell Line Gene Expression Profiles	-1.0	-0.842936
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE254848_4_v_3_ptges_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43605
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869424
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0579
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44762
GSE239436,GSE239441_0_v_1_keap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930377
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.8394
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.81683
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08161
KAT2B	ENCODE Transcription Factor Targets	1.0	null
placenta	HPA Tissue Protein Expression Profiles	-1.0	-1.54327
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.533083
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01265
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RH4	DepMap CRISPR Gene Dependency	1.0	2.63716
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Choriocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34838
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	1.0	2.28925
5190_MRGBP_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.545193
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08298
IGR1	DepMap CRISPR Gene Dependency	1.0	2.70941
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93383
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38934
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05579
KDM4A	ENCODE Transcription Factor Targets	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36434
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.26097
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75693
Perturb_2225_KO_Celf6_SRP289451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52304
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0102
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4758-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor neuron atrophy	GWASdb SNP-Phenotype Associations	1.0	0.525058
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7567-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90176
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.23861
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.45509
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46172
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32177
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78932
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61399
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855565
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.91187
SIRT6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46916
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36705
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824505
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0604
11145_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510488
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
KP3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97124
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32249
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.59052
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5191
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21272
MBD4	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19723
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98774
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Unnamed_2_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992072
STAT4	ChEA Transcription Factor Targets	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59347
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Zinc finger, C2H2-like	InterPro Predicted Protein Domain Annotations	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19045
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50924
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06294
NUP93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31976
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970427
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2994
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950624
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0604
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41917
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860099
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Supplementary_Table_7_Transcription_factors_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79493
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878631
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12976
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48087
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976751
MAFF	ENCODE Transcription Factor Targets	1.0	null
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46499
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06797
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31486
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995022
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29556
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11149
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52882
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831177
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.826253
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	3.43541
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966101
Senicapoc	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08004
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02206
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.64298
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86719
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925673
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01973
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1581	DepMap CRISPR Gene Dependency	1.0	2.4556
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24872
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07846
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05075
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8330_KO_TXNDC9_SRP141214	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2982
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52099
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12951
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889133
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30477
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877051
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03971
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918141
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.63732
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57631
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20272
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7478_RPL7L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.595922
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929446
VDR-21846776-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00097
Peripheral nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.611
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
prostate	GTEx Tissue Gene Expression Profiles	1.0	1.00772
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32854
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3930188-813067.f1.pdf-159-ZNF384_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90778
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33225
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21931
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1043
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01883
UMUC16	DepMap CRISPR Gene Dependency	1.0	6.06931
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12606
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47383
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863563
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-WL-A834-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.19979
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112995,GSE132079_1_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20877
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06561
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81356
ZBTB33_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837068
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06054
TE5	DepMap CRISPR Gene Dependency	1.0	2.44162
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNUC5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.606
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.573887
Perturb_16353_KD_Nr5a2_SRP325052	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32423
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.554278
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02349
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29886
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2455
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21238
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11005
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6812
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.83345
Retinal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948545
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5803
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO679	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58549
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61387
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.56929
Golgi medial cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.813
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-1726-SM-47JXP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21886
BL3721 (KDM4B)	NURSA Protein Complexes	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06164
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8603
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961651
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92359
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867443
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGFBR1_knockdown_102_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.64399
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11422
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933041
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.951383
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC3_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	6.81619
binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65162
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100670_TCx_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09801
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.926775
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1741
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4491_L3MBTL1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508788
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25999
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8014
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.12296
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15704
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906239
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79488
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17404
TRIM28	ENCODE Transcription Factor Targets	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6C_mageckTFkoscreen_wo_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
SNU216	CCLE Cell Line Gene Expression Profiles	1.0	1.66976
ESS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62337
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5876
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.95025
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11546
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2703
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DPF2_02_14	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59986
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.45453
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02001
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7522
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10159
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925557
abnormal head shape	IMPC Knockout Mouse Phenotypes	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
chr19_8511978_G_C_b38	GTEx eQTL 2025	1.0	1.62148
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.00887
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8124
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63405
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00099
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05132
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6120868-41598_2018_30702_MOESM3_ESM.xlsx-FGF2-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876391
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93484
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79577
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.722
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02322
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61836
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15587
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03432
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63131
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH661	CCLE Cell Line Gene Expression Profiles	-1.0	-2.71221
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13528
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spironolactone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12013
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.55693
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984455
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.850347
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-48-ZNF226_ZNF226	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_15_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06921
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99147
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SEM	DepMap CRISPR Gene Dependency	1.0	2.50561
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A204	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04895
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866221
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54373
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.964
BL3720 (KDM4B)	NURSA Protein Complexes	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
NCIH2110	DepMap CRISPR Gene Dependency	1.0	2.00306
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4639
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10806738-mmc2.xlsx-Table_S1-Table_S1_Table_of_significantly_adjusted_p-valued_0_05_up-regulated_genes_log2FC_1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
motor neuron disease	GWASdb SNP-Disease Associations	1.0	0.618434
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25999
AKR1C3-IN-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0009
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0899
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
7512_RPS23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.56433
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.38014
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30492
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18042
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10669
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29354
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.98044
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43288
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87611
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44773
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33857
SPI1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887663
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.928789
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.957268
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.44151
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17363
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828881
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873755
GSE201270,GSE201272_0_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03621
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01863
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923111
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.74857
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64827
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.312
GSE198165,GSE198166_0_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04244
COV644	DepMap CRISPR Gene Dependency	1.0	2.08445
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.04129
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04476
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905289
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841996
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306606
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32474
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal motor neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.525058
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05182
Lung squamous cell carcinoma_LUSC_TCGA-33-4586-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94743
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01411
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16888
GSK3B_knockdown_158_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44304
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17299
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50616
SET2	CCLE Cell Line Gene CNV Profiles	1.0	1.9469
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00649
abnormal head size	MGI Mouse Phenotype Associations 2023	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844343
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13537
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5U8-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	2.79415
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38441
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31046
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PC3	DepMap CRISPR Gene Dependency	1.0	2.74855
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32718
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03438
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10136
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.919127
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848992
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200358
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01017
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845541
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDAN1_02_197	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59452
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91195
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.1735
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2267
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18743
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11104
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836486
SET2	DepMap CRISPR Gene Dependency	1.0	3.00512
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
rectum	HPA Tissue Gene Expression Profiles	-1.0	-1.11753
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257538
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991748
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07611
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.93218
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894529
colon_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.855625
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868077
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9043
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962617
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924633
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10350897-j_biol-2022-0528-S1.pdf-191-ZNF385D_ZNF385D	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24032
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970978
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99189
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05265
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10702
GTEX-REY6-1726-SM-48FDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828608
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34068
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57397
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.987876
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_1_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB3A_KO_GDS2483_700_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860788
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983235
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24797
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-149	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27349
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.27448
KYM1_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	2.90689
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63689
RBPJ	ChEA Transcription Factor Targets	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90199
Stage I neutrophil_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.19754
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026547
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
NCIH2030_LUNG	CCLE Cell Line Proteomics	1.0	6.33128
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERG	ChEA Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220648
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC-O 9311	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17644
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883094
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85975
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213103
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5471
TIG3TD	CCLE Cell Line Gene Expression Profiles	1.0	1.50177
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21495
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72173
KMS27	CCLE Cell Line Gene CNV Profiles	1.0	1.38763
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6506
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87983
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88516
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.51099
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09321
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914458
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81356
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.96277
NC-76-YX69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20225
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01516
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866863
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08464
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.12803
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2473
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.861403
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	7.59901
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0604
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.73694
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49761
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXM1_02_37	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59372
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16692
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.771
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10263
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46283
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91389
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6798-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836093
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30296
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17404
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.29963
8665_TAF5L_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.532528
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
10061_ZEB2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511917
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94026
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26516
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22579
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836564
Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54353
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22678
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72006
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.285395
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47136
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SARS-BatSRBD_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.47314
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.045
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8637
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264245
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831529
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1200_KNL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.836569
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91692
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.86641
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00977
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9545
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-a-Classification_of_camel_SON_basal_genes_-_transcription_factors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.46603
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04111
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22533
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28921
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64862
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997975
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26102
Leupeptin	DeepCoverMOA Drug Mechanisms of Action	1.0	1.19
abnormal neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.525058
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954341
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64196
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	4.19781
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20254
HMGN3	ENCODE Transcription Factor Targets	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56129
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adipose tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918159
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.33033
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211182
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10795
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	DepMap CRISPR Gene Dependency	1.0	2.00714
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70739
PMC6996832-pone.0228590.s007.xlsx-Double_KD_up-regulated_TFs-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.87645
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07057
Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30799
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837361
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.54327
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	2.30291
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59341
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78031
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99487
CHD1	ENCODE Transcription Factor Targets	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5202
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10224
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Spliceosomal tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cloprostenol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06444
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.23885
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.65905
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.4996
GSE193541_0_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	1.0	2.85948
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22206
ELF1	ENCODE Transcription Factor Targets	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.379
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84174
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Defactinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.49
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32786
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38949
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16408
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.90146
MYC_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.68033
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22907
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	2.58064
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.90456
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32537
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838238
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12507
regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843145
Isolated cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
2263_DMTF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.866443
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.35787
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52967
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07613
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47252
Carpal tunnel syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.611
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64769
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859474
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTBP1_02_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62445
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1363
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03767
VDR	ChEA Transcription Factor Targets	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16065
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993829
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.40439
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57757
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09296
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.024155
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978637
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891227
MKN74	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77102
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7608
GATA2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67238
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-1.xlsx-Sheet1-LISA_analysis_identifies_potential_co-regulators_of_genes_upregulated_in_FOXO3_high_GBMs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909723
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.52868
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11475
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13566
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73373
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35704
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849216
HEKTE	CCLE Cell Line Gene Expression Profiles	1.0	1.49631
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927572
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4165-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8945
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74167
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34742
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984455
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897685
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909814
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830488
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28814
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56993
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4065
hek293	HPA Cell Line Gene Expression Profiles	1.0	2.14686
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97581
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.049999
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.80058
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
PMC10795826-jciinsight-8-170518-s128.xlsx-Fig_5B-Gene_Regulated_by_VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11041
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0476
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03804
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838442
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21495
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59395
Lung adenocarcinoma_LUAD_TCGA-55-8090-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.850713
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3207
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54586
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58394
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32296
Head and Neck squamous cell carcinoma_HNSC_TCGA-HL-7533-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301105
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937352
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5399
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00782
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321253
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41565
AD-34-TG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274466
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42142
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18632
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2031
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sulfanilamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16622
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50178
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52229
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13283
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMRC20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38269
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN340	CCLE Cell Line Gene Expression Profiles	1.0	2.04422
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.09665
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.55557
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4945
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59782
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19883
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833474
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21359
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05311
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79357
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-2.73153
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96859
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825421
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03635
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06267
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968878
EW8	CCLE Cell Line Gene Expression Profiles	1.0	1.40148
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.611
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893525
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926704
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564134
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86487
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55784
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08915
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246012
ARID3A	ENCODE Transcription Factor Targets	1.0	null
JM1	DepMap CRISPR Gene Dependency	1.0	3.64815
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985034
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.08154
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79444
PBX3	ENCODE Transcription Factor Targets	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984455
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959379
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23195
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HFI-142	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86763
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48939
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11328671-jitc-12-4-s003.pdf-445-ZNF397_ZNF397	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.25044
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30628
SMC3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15079
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17754
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10537
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49238
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.43758
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40631
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12374
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6064
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18039
MM160113	DepMap CRISPR Gene Dependency	1.0	2.51703
MTA3	ENCODE Transcription Factor Targets	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60003
Pancreas	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	1.43356
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980104
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34357
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97931
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950369
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18289
ATF2	ENCODE Transcription Factor Targets	1.0	null
AA92593	DeepCoverMOA Drug Mechanisms of Action	1.0	0.52
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04128
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895518
WM88	DepMap CRISPR Gene Dependency	1.0	3.0042
TP63	ChEA Transcription Factor Targets	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03252
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5804
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07721
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06553
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33974
HOXC9	ChEA Transcription Factor Targets	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	DepMap CRISPR Gene Dependency	1.0	3.32121
LNZ308	CCLE Cell Line Gene Expression Profiles	1.0	1.88917
nucleus	GO Cellular Component Annotations 2015	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09661
GATA4	ChEA Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_1_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57945
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.817193
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94261
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04635
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55673
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00062
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71547
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.907854
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986054
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22644
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282636
Interferon regulatory factor 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.829828
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2791
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852985
SARS-CoV MA15_Day1-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74181
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31038
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19483
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16121
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842018
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24223
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17434
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967603
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22228
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53461
JUND	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3986
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42608
2925_FAM50A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.582554
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05165
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992683
KAT2A	ENCODE Transcription Factor Targets	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38176
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30028
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62975
HDAC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.917856
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2005
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19058
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88852
Palatine uvula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43084
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62156
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895385
Perturb_8728_KD_ZNF414_SRP269946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47041
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.525058
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922004
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.35571
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992202
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07683
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
RBE	DepMap CRISPR Gene Dependency	1.0	3.65419
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898907
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876876
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935712
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26781
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81117
OCUM1_STOMACH	CCLE Cell Line Proteomics	1.0	3.5583
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89767_4_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.738885
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35173
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7933
JHESOAD1	CCLE Cell Line Gene Expression Profiles	1.0	2.02353
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846226
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42649
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6467
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UTP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0297
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17282
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9747
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50808
SW403	DepMap CRISPR Gene Dependency	1.0	3.20118
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73218
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38134
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03781
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913064
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.902411
PAX5	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874186
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.611
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824155
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4033
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24511
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45191
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1103
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54961
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.962975
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organic cyclic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85422
Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERK7	Kinase Library Serine Threonine Kinome Atlas	1.0	null
COLO201	DepMap CRISPR Gene Dependency	1.0	2.1698
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548o	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985247
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94759
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26261
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.55208
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98443
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36063
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.907039
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73445
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UT7	CCLE Cell Line Gene CNV Profiles	1.0	2.231
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35466
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01057
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.2864
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19488
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96015
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.45816
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78537
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL47	DepMap CRISPR Gene Dependency	1.0	2.94666
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946032
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	0.967637
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37406
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.953632
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGO1_02_95	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60666
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7579
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4758
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D283MED	DepMap CRISPR Gene Dependency	1.0	2.85797
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75616
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18151
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22575
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEMBL570596	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.35456
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35189
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_10_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Perturb_4217_OE_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.40891
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4795
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.023255
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.5396
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36803
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.36723
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72031
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64667
Nager acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279143
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30121
ZBTB16-27035670-HESC-HUMAN-ENDOMETRIAL	ChEA Transcription Factor Targets 2022	1.0	null
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35868
H3K36me3_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN215	CCLE Cell Line Gene Expression Profiles	1.0	2.35651
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63039
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02581
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19049
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3432
EFNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21013
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.64557
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.929372
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68851
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.0059
MAP3K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22324
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dna binding	GO Molecular Function Annotations 2015	1.0	null
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15979
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0148
abnormal facial morphology	IMPC Knockout Mouse Phenotypes	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3778-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYLK_knockdown_49_GSE14525	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.81247
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05781
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24651
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47802
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3372
abnormal head size	IMPC Knockout Mouse Phenotypes	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556232
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05296
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.098
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925605
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73272
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pc3	HPA Cell Line Gene Expression Profiles	1.0	0.956027
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2731
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07553
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.54327
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.995755
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4711
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964997
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01225
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32959
Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE186440,GSE186443_3_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43453
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3349
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00708
GSE201251_2_v_3_coumarin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911139
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nobox_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.581904
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06894
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE253056_0_v_1_erythropoietin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05505
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11901
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869223
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84151
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886261
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51667
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3865
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867734
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06751
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949032
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4323
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.84033
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4253
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.061
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50543
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
aromatic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.894683
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.44876
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04855
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.662111
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25206
ZC3H7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10193
CAKI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58753
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01361
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12049
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1816
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61785
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.92214
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.971723
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45694
9420_TUBB_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.93448
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90546
BT483	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33846
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20305
connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57117
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36172
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1	ChEA Transcription Factor Targets	1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
Neuronal dense core vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.544
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14039
Lung adenocarcinoma_LUAD_TCGA-MP-A4TD-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40744
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
6263_PGPEP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.561002
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48103
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52096
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986111
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23497
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07378
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887856
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36915
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5546
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ginkgolide A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929319
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13714
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16607
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WP-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HSOS1	DepMap CRISPR Gene Dependency	1.0	2.44701
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08011
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11811
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885555
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09311
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2197
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03225
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966412
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81964
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	1.9295
ZNF263	ENCODE Transcription Factor Targets	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35096
abnormal head shape	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44628
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94644
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849981
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03889
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0604
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12738
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16775
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05048
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896933
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.55272
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24794
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.08837
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1868
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208589
CCK81	DepMap CRISPR Gene Dependency	1.0	3.6719
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10861
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231738
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_18_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939494
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tizanidine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.5
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.3843
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59836
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27136
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8107
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.57435
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7925
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.931341
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46794
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.366891
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43341
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990916
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10122
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16449
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61407
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58532
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37337
CCND1	ChEA Transcription Factor Targets	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08059
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.343
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54418
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216841
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88128
all	GWASdb SNP-Phenotype Associations	1.0	0.02835
SOX11	ChEA Transcription Factor Targets	1.0	null
PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.16718
MAZ	ENCODE Transcription Factor Targets	1.0	null
FGFR1_drugactivation_149_GSE32316	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.37489
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0383
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264758
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4598_LIN9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.56579
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11263
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03719
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56159
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	7.4055
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852112
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959885
Darunavir	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anophthalmia	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32048
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Unnamed_2_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01786
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918996
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_KO_GDS3732_148_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24339
Siponimod	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32759
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32373
Nerve compression syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.611
nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.96286
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5323-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11741
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24093
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07558
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212447
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC11867302-mmc4.xlsx-Table_S5-Table_S5_Single-cell_transcriptome_differential_gene_analysis_DEG_results_for_all_of_our_potential_causal_genes_analyzed_by_MR_and_colocalization_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10331759-jgo-14-03-1307-supplementary.pdf-1-ZNF350_ZNF350	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-559-ZNF266_ZNF266	Rummagene Transcription Factor Associations 2026	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62568
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-13-CX28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246452
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923425
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.61161
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.77491
PMC12281655-CPB-26-6-935_SD1.pdf-20-ZNF500_ZNF500	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839444
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02167
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927961
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82063
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16462
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGR37_SKIN	CCLE Cell Line Proteomics	1.0	2.81137
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941043
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05277
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19986
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04767
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2313_DNM2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.548816
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33139
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1166
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.1923
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61748
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SF767	CCLE Cell Line Gene Expression Profiles	1.0	1.54613
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.969067
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.11103
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20215
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0476
8788_TCFL5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512482
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17234
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08116
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1740_COG1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.553022
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900159
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.611
MM1S	CCLE Cell Line Gene CNV Profiles	1.0	1.35417
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09678
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09221
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01195
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842216
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04855
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.916172
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32213
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal facial morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15721
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49278
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06255
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23833
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.49918
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04093
UACC62_SKIN	CCLE Cell Line Proteomics	1.0	2.5297
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	2.02575
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09012
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4819
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.43587
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ACHN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95756
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06181
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13323
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03741
BRCA1	ENCODE Transcription Factor Targets	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35685
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02044
EFM19	DepMap CRISPR Gene Dependency	1.0	5.91325
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4321
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17408
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07615
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938653
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25999
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08348
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
HG3	DepMap CRISPR Gene Dependency	1.0	3.98531
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906563
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97683
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04548
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5008
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0848
ETS1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65675
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25711
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13909
microcephaly	IMPC Knockout Mouse Phenotypes	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98726
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553326
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11364504-41388_2024_3115_MOESM2_ESM.pdf-76-ZNF219_ZNF219	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833215
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32878
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6D_mageckTFkoscreen_with_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05383
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06306
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872013
SRF	ENCODE Transcription Factor Targets	1.0	null
CSNK2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78314
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13909
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25413
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87741
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07089
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995028
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45405
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69784
PMC12003887-41467_2025_58921_MOESM16_ESM.xlsx-Figure_4a-Figure_4a_Average_normalized_activities_of_1_358_TRs_in_ESR1-knockout_experiments_analyzed_for_both_up-_and_down-regulated_gene_sets_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983047
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02744
GSE180468_2_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35384
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60911
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3479
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LOXIMVI_SKIN	CCLE Cell Line Proteomics	1.0	3.46134
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21592
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSC3	DepMap CRISPR Gene Dependency	1.0	2.02679
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01895
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992531
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Climbazole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24241
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.093987
USF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S4-Supplemental_Table_S4_Genes_commonly_upregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69351
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03444
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.769407
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.323
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40744
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.34965
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23076
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12502
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32796
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1568
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3B_knockdown_209_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.44304
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881683
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.79904
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87897
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47421
9656_USP39_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.636612
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89003
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6120868-41598_2018_30702_MOESM3_ESM.xlsx-IL1beta-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
Imiquimod	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70234
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43487
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11021
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869237
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.33965
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.302937
GATA2	ChEA Transcription Factor Targets	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03412
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78535
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925913
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12303
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.50461
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.31204
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07417
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	0.824178
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06003
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
15489324-TableS2	GeneSigDB Published Gene Signatures	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13449
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829913
LPS6	DepMap CRISPR Gene Dependency	1.0	2.29427
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.54327
regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
GSE57871_5_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75913
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828233
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1501
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73095
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03345
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52612
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25665
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.875658
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00147
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
hsa-miR-4313	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228275
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38907
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28355
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WZ811	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93788
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16449
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52124
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05859
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MK2206	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.57
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881473
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40744
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06548
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13923
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.920822
TAL1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr19_8510234_G_C_b38	GTEx eQTL 2025	1.0	2.66949
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00725
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00335
PANC0327	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67781
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20609
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14279
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936753
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64222
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13884
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851377
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39719
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4418
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.01029
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.93857
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
adipose tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988055
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	1.0	1.63392
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963951
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55496
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00705
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40892
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55722
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4642
SIX5	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49732
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934803
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04794
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97254
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64295
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13395
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873755
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15366
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853979
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14368
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04859
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04855
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2866
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3921136-CIN-13-2014-021-s001.pdf-226-ZNF318_ZNF318	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23037
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.3404
hsa-miR-1323	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.61288
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942464
anophthalmia	IMPC Knockout Mouse Phenotypes	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363721
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.894107
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08904
CAL33_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	5.2226
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.705788
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20592
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02587
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_unique_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Relationship_between_C2H2-ZNF_gene_expression_and_DNA_methylation_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850947
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1723
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11462941-CAS-115-2947-s001.pdf-103-ERF_ERF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CORL279	CCLE Cell Line Gene CNV Profiles	1.0	1.61451
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38756
LOXIMVI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42739
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0225
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7818
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60087
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955729
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31199
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
H3K9me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.41425
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44759
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39703
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.4582
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.068881
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08781
ECC4	DepMap CRISPR Gene Dependency	1.0	2.94783
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Dimethylfraxetin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.75
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05026
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47884
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27403
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEX11	Pathway Commons Protein-Protein Interactions	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3351
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nisoldipine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96146
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38007
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0434
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16072
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	CCLE Cell Line Gene CNV Profiles	1.0	1.69414
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97254
NSC 23766	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917335
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.61274
SRP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12745
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985034
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863956
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68066
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05884
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGF1R_druginhibition_46_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.69531
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23742
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96129
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942061
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884233
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329461
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23717
Diamond-Blackfan anemia 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.4924
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872645
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12189
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92564
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47578
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.885392
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841756
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34031
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29683
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.896488
Calcipotriol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.8
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DC-01A-31R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20751
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB69	DepMap CRISPR Gene Dependency	1.0	2.67425
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83281
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50381
GSE186767_1_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92458
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WB-82-EL69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223881
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.917
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9279
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953921
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903507
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38872
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16216
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52229
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34846
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986934
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.55377
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944614
Hyperplasia	CTD Gene-Disease Associations	1.0	1.0561
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.838432
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986689
Perturb_2467_KO_NAT10_SRP388804	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.05192
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944002
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleobase-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18484
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901138
ELK4	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JK-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20565
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3573
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984455
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37172
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921601
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null