association	dataset	threshold value	standardized value
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216222
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6317
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.46
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.088
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.5056
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.5166
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.22
GSE179693,GSE179694_4_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	228.037
PMC10769395-media-8.xlsx-S8E_ETS1_ETS1-ChIP_down-Unnamed_1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.835
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1116
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3682
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6693
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.578
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2013
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	200.674
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7284
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.996
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0506
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.219
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.8886
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6112
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2965
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	266.388
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8704
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3268
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9615
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0093
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	171.47
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.63
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2898
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4659
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9638
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.77
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2904
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.9643
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0285
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5507
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3478
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.9403
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.254
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.013
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.379
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.156
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7998
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6214
HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2224
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5225
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.556
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	220.792
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6525
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209995
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0475
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2613
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5455
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2225
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1218
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0614
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7853
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.3874
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.3512
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.379
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10769395-media-8.xlsx-S8E_ETS1_ETS1-ChIP_down-Ebegboni_et_al_Supplemental_Table_S8E_Genes_decreased_following_the_ectopic_expression_of_ETS1_and_bound_by_ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216862
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3649
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1742
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8986
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0845
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.0999
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.178
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5553
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2574
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9852
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3963
PMC10769395-media-8.xlsx-S8E_ETS1_ETS1-ChIP_down-Unnamed_6_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246645
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3885
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.4053
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2539
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.813
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.615
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.592
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7866
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.916
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.5268
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9583
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203552
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5349
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3093
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2799
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	204.061
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.773
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.7269
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.5964