association dataset threshold value standardized value basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00484 H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SW 527 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.7465 ARHGEF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90776 GTEX-O5YT-0526-SM-32PK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08622 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27531 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08171 substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78419 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB Rummagene Transcription Factor Associations 2026 1.0 null TMEM129 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82161 Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11087 ZNF322 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42377 RBBP5 ENCODE Transcription Factor Targets 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ELOVL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54013 GSE163884_1_v_0_sumo2_human RummaGEO Gene Perturbation Signatures -1.0 null nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.966204 GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09866 CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44451 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.1255 PMAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90098 GSE205729,GSE205731_2_v_0_tazemetostat_human RummaGEO Drug Perturbation Signatures -1.0 null ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARG ChEA Transcription Factor Targets 1.0 null ANKRD16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85327 BACH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6649 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29596 POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DVL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52389 GSE106661,GSE106665_0_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38918 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null GTEX-S4P3-1126-SM-4AD52 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0299 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7686 GTEX-PLZ4-2726-SM-3P61A GTEx Tissue Sample Gene Expression Profiles 1.0 1.40866 Gene expression (Transcription) Reactome Pathways 2024 1.0 null abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.118249 FIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22744 MAGED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22136 HSFX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07638 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32905 mantle zone of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.11089 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38751 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5425 CANX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99733 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10486 GTEX-TML8-1126-SM-4DXSS GTEx Tissue Sample Gene Expression Profiles 1.0 1.12367 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ITGB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9817 RPRML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50076 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.9959 MZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3367 MMP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43359 GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34507 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0431 PMC6307949-jci-129-122819-s120.xlsx-SupplementaryTable9-SU2C_PCF_Cohort_n_122_AR-V7_RNA_FKPM_vs_gene_expression_FKPM_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE187006_3_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null caco2 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 143B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14615 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.45448 MZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.909606 HEPG2 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -2.62612 CAMK2N1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4047 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.4397 mantle zone of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30142 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB Rummagene Transcription Factor Associations 2026 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 ARF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72964 BTD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05649 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.885072 MPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32755 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of transcription, dna-templated GO Biological Process Annotations 2015 1.0 null intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26441 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Krueppel-associated box InterPro Predicted Protein Domain Annotations 1.0 null GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978439 GTEX-WFG7-1326-SM-4LMK1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17779 SU-DHL-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.7499 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83277 EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158834_10_v_3_palm_human RummaGEO Gene Perturbation Signatures 1.0 null Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879595 H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.94127 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZDHHC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94004 RTL8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12712 SMYD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8952 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.859136 GSE147876,GSE147877_2_v_8_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.831243 GTEX-QVUS-0626-SM-447CC GTEx Tissue Sample Gene Expression Profiles 1.0 0.899427 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior pretectal nucleus, dorsal core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19729 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40633 regulation of biological process GO Biological Process Annotations 2015 1.0 null SP2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHRNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.705 H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93771 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SIPA1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62621 GSE48812_7_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14138 GTEX-XBED-1126-SM-48TCF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93238 POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null TMEM179B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98841 superficial stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10058 H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37115 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE228106_0_v_1_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB Rummagene Transcription Factor Associations 2026 1.0 null H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE133329_1_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935876 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09709 PTBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8022 GTEX-PWOO-0526-SM-2S1Q3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02998 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0593 POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0184 layer 4 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74964 GTEX-R55C-1026-SM-48FCM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.876136 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MARCHF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01654 APP_KO_GDS4414_370_mouse_prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MM485 DepMap CRISPR Gene Dependency 1.0 2.11021 GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.00393 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28211 GSE207728,GSE207808_2_v_1_c646_human RummaGEO Drug Perturbation Signatures -1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null 19286929-SuppTable2q GeneSigDB Published Gene Signatures 1.0 null GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null SLC7A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33131 reticular formation of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60281 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38994 layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67219 GTEX-WEY5-1026-SM-4LMK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.882235 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.57508 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08351 SLC25A22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72227 GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10364 GTEX-PSDG-0008-SM-48TE5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03302 Brain - Putamen (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 0.357026 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27305 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18868 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.17047 icSARS CoV_54Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.806491 GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles 1.0 1.74881 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29431 GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.7564 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.960394 GSE205163,GSE205164_5_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 1.07857 GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 OCIAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42986 NCIH2110 CCLE Cell Line Gene CNV Profiles -1.0 -1.72471 GTEX-SIU7-1626-SM-4BRUK GTEx Tissue Sample Gene Expression Profiles 1.0 1.5772 PHF8 ENCODE Transcription Factor Targets 1.0 null GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.51769 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03557 cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null GSE158969_1_v_2_trastuzumab_human RummaGEO Drug Perturbation Signatures -1.0 null basal nucleus of Meynert Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934676 ANXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66846 GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PX3G-1526-SM-48U11 GTEx Tissue Sample Gene Expression Profiles 1.0 0.841479 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XUW1-0926-SM-4BONX GTEx Tissue Sample Gene Expression Profiles 1.0 0.90861 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10645 GTEX-P78B-0426-SM-2I5F5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845821 NXF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39718 LIN7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56587 striohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54726 GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43558 POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null metal ion binding GO Molecular Function Annotations 2015 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_2_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE169152_3_v_2_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-X4XY-1026-SM-46MVX GTEx Tissue Sample Gene Expression Profiles 1.0 0.933279 Mobilized_CD34_Primary_Cells_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.22592 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures 1.0 null PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18 Rummagene Transcription Factor Associations 2026 1.0 null H4 CCLE Cell Line Gene CNV Profiles 1.0 1.62038 ZNF354C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35692 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.982817 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47435 Entorhinal area, medial part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26441 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.0042 HOXA10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70854 GTEX-XXEK-0926-SM-4BRWH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04459 GABPA_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BBC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44711 H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB Rummagene Transcription Factor Associations 2026 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.977574 ELK1 ENCODE Transcription Factor Targets 1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5922 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RD-ES cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.856 CTCF ENCODE Transcription Factor Targets 1.0 null neoplasm GWASdb SNP-Phenotype Associations 1.0 0.041608 Entorhinal area, medial part, dorsal zone, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78615 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60995 MGAT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65239 IFT140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60121 lateral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03927 HDLM-2 COSMIC Cell Line Gene CNV Profiles 1.0 2.12439 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB Rummagene Transcription Factor Associations 2026 1.0 null TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.826157 TAF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMMY-1626-SM-4DXTY GTEx Tissue Sample Gene Expression Profiles 1.0 1.5281 medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04532 GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.967406 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MRGPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44295 Ewing's sarcoma family tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21977 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Anterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22625 Bed nuclei of the stria terminalis, anterior division, ventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13379 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AMFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.93165 SMAGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78798 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-U3ZN-2126-SM-4DXU1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06287 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1395 NCI-H727 COSMIC Cell Line Gene CNV Profiles 1.0 2.12439 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.952423 GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946641 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.830705 HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.924487 GTEX-PWN1-2526-SM-48TDS GTEx Tissue Sample Gene Expression Profiles 1.0 1.60267 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-0526-SM-2TF64 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20534 ULBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64885 MYC ENCODE Transcription Factor Targets 1.0 null Artery - Tibial GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.630757 PIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68974 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.869921 ACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32837 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TET1 ChEA Transcription Factor Targets 1.0 null Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08351 GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972666 PM20D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15428 GTEX-S341-1526-SM-4AD6K GTEx Tissue Sample Gene Expression Profiles 1.0 0.899035 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WY7C-2326-SM-3NB2U GTEx Tissue Sample Gene Expression Profiles 1.0 1.15861 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.896 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-658 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 IP6K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61641 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.979335 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ventral juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.57642 STK31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2712 GSE182680,GSE182683_5_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE158969_1_v_0_trastuzumab_human RummaGEO Drug Perturbation Signatures -1.0 null GATD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04696 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Taenia tecta, dorsal part, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24368 SLC25A15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24747 HBEGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55319 PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 1.13622 MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.929811 H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null WTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.51871 hsa-miR-4768-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 1.0 2.20912 layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30893 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.8548 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NGRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85669 Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20113 hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.051809 GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 RSL1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43208 CDK8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56723 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5478 GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.956915 GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles 1.0 1.1489 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25967 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MRPL37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52868 CDIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89769 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05467 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Fanconi anemia complementation group B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.529 GSE221327_4_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Basolateral amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00559 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.870203 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.09958 ZNF143 ENCODE Transcription Factor Targets 1.0 null GTEX-W5X1-0001-SM-3P61V GTEx Tissue Sample Gene Expression Profiles 1.0 1.32934 TXNL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34297 RYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83938 POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 Omegae TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.123 GSE130437_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.934101 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.30077 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_2_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB Rummagene Transcription Factor Associations 2026 1.0 null GPR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64885 GSE175787_4_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.181 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MKRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09505 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00898 GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.142 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WYVS-2126-SM-3NMA3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11945 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06714 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.901873 SNU1076 CCLE Cell Line Gene CNV Profiles -1.0 -1.43151 NFYA ENCODE Transcription Factor Targets 1.0 null B4GALT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3162 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.37371 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.5224 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.868619 GTEX-WYJK-1726-SM-3NM9U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33247 lung cancer GWASdb SNP-Disease Associations 1.0 0.509492 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PMC12464728-HSR2-8-e71283-s003.docx-31-1150_ZNF350_1_ZNF350 Rummagene Transcription Factor Associations 2026 1.0 null CW-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3068 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08351 SV2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83334 H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null GSE216273,GSE216292_0_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null MSH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25366 GSE182680,GSE182683_10_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE182770,GSE182784_0_v_1_chd2_human RummaGEO Gene Perturbation Signatures 1.0 null AU565 COSMIC Cell Line Gene CNV Profiles -1.0 -3.15179 FOS ENCODE Transcription Factor Targets 1.0 null SLC35C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08874 GSE224096_3_v_0_cocaine_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-V955-1326-SM-4JBHR GTEx Tissue Sample Gene Expression Profiles 1.0 1.22758 RHBDL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89598 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03791 HHEX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27972 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32264 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GATA4_KO_GDS3486_483_mouse_jejunum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE227698_5_v_3_g0s2_human RummaGEO Gene Perturbation Signatures -1.0 null magnocellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42473 commissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69554 r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2995 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE182680,GSE182683_7_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Liver-nk cell Tabula Sapiens Gene-Cell Associations 1.0 0.112475 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5772 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.976949 MIOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54914 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38373 H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF343 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92054 KAT2A ENCODE Transcription Factor Targets 1.0 null PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null km3 HPA Cell Line Gene Expression Profiles 1.0 0.973531 Zinc finger C2H2-type/integrase DNA-binding domain InterPro Predicted Protein Domain Annotations 1.0 null GSE239844_11_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 STX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20183 peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01672 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null PARP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58461 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WH7G-0426-SM-3NMBJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10689 NCOA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4769 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30149 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40824 YY1_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33342 H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.856431 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19293 GTEX-XV7Q-1226-SM-4BRVT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980381 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898682 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHLDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41594 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6996832-pone.0228590.s007.xlsx-Double_KD_down-regulated_TFs-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.11495 FN3KRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43573 MZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4554 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00301 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH841 CCLE Cell Line Gene CNV Profiles 1.0 1.75993 GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.832176 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22504 KDM5B-21448134-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44948 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4866 PMC7021771-41467_2020_14684_MOESM12_ESM.xlsx-CASZ1_ChIPseq_in_Ctrl_cells-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WYBS-1226-SM-3NM9N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01407 SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFYA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3594 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB Rummagene Transcription Factor Associations 2026 1.0 null EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE160304,GSE163392_7_v_3_zswim8_human RummaGEO Gene Perturbation Signatures 1.0 null YY1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE258991_5_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08888 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03172 r4 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69268 NCIH1944 CCLE Cell Line Gene CNV Profiles -1.0 -1.67554 GTEX-TKQ1-0003-SM-3NMAE GTEx Tissue Sample Gene Expression Profiles 1.0 1.25698 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40089 CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null adrenal_4c HPA Tissue Sample Gene Expression Profiles -1.0 -0.825585 KYSE220 DepMap CRISPR Gene Dependency 1.0 2.55224 NO11 DepMap CRISPR Gene Dependency 1.0 4.70269 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 cellular nitrogen compound biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-V955-0004-SM-3NMDH GTEx Tissue Sample Gene Expression Profiles 1.0 1.03225 Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13679 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7286 GLUD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10469 superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59694 GTEX-R55G-0826-SM-2TC5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.08768 SLC25A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56868 H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K79me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF3 ENCODE Transcription Factor Targets 1.0 null ENO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5281 HGC27 CCLE Cell Line Gene CNV Profiles 1.0 1.47801 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11478 SEMA4G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67853 CHD2 ENCODE Transcription Factor Targets 1.0 null Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51689 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-1326-SM-3MJHO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958126 H3K36me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44116 PGR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65799 DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3009 GSE164505,GSE164506_3_v_2_indisulam_human RummaGEO Drug Perturbation Signatures -1.0 null ENGASE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46454 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE74251_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3068 GTEX-S3XE-0426-SM-3K2AC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 MZ in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01344 GNPDA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66227 GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40494 TSR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8845 HCC1806 COSMIC Cell Line Gene CNV Profiles 1.0 2.12439 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FIGLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63014 GTEX-XPVG-0626-SM-4B65B GTEx Tissue Sample Gene Expression Profiles 1.0 0.875779 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.33468 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.934139 SELENOI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41635 SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.58631 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.16366 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGFBR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91576 MAX ENCODE Transcription Factor Targets 1.0 null tonsil_8a1 HPA Tissue Sample Gene Expression Profiles 1.0 0.891924 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.982 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09696 mantle zone of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70361 GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46917 r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3008 GTEX-U3ZH-2026-SM-3DB78 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39014 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cytoplasmic vesicle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.708 ASCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.66053 GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles 1.0 0.867668 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95496 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EFS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72004 superficial stratum of r4BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69268 SIN3A_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H1 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.84018 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36693 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.57064 H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4155 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870813 regulation of rna metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.982617 ATP5IF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91593 IRF1 ENCODE Transcription Factor Targets 1.0 null GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 0.951147 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1892 GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0871 Pancreas GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.948258 PTPRZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58808 hESC_Derived_CD56+_Ectoderm_Cultured_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.08024 KIAA1143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43794 Pretectal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06615 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28954 GRIN3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8276 icSARS CoV_36Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.09155 H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VEZT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39474 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.02151 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LRFN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51812 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.56393 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.925603 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21839 GABPB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82939 lateral part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39648 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1528 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.894175 SF172 CCLE Cell Line Gene CNV Profiles 1.0 2.71214 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910745 layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37981 GSE158834_10_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 0.844117 HT1376 CCLE Cell Line Gene CNV Profiles -1.0 -1.59243 HUH7 CCLE Cell Line Gene CNV Profiles 1.0 1.6136 molt4 HPA Cell Line Gene Expression Profiles 1.0 1.24972 GSE161800_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null SCAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53352 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Small_Intestine Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.02386 HSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86488 RALA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1826 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54983 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null hsa-miR-4459 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01384 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-WFON-0226-SM-3GIKR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01145 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11508 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9 Rummagene Transcription Factor Associations 2026 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null GTEX-P78B-2226-SM-3P5ZZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.21712 5637 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.17 EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Breast_Myoepithelial_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.829885 MPLKIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94046 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PML ENCODE Transcription Factor Targets 1.0 null LRFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24042 cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null SOX14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9695 cellular metabolic process GO Biological Process Annotations 2015 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE81796_0_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14584 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12281655-CPB-26-6-935_SD1.pdf-20-ZNF500_ZNF500 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null stratum pyramidale of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868077 FIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87066 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.936638 PIK3C2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1175 BSX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40982 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.988797 GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27957 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42243 subthalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07258 PIGW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83176 CUX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68696 GSE145990_1_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null ASH2L ChEA Transcription Factor Targets 1.0 null MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26159 ventral part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46815 GSE105169,GSE105175_0_v_1_dhx36_human RummaGEO Gene Perturbation Signatures -1.0 null COX7C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16364 Central amygdalar nucleus, capsular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05684 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.49454 GSE158834_12_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null ST6GAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38403 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0717 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05294 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09009 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.00328 Entorhinal area, medial part, dorsal zone, layer 6 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47084 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PEX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75753 NPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3391 H3K4me1_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GOLGA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82395 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96275 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -2.07549 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18766 lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24461 GAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44483 GTEX-WFON-0001-SM-3P61W GTEx Tissue Sample Gene Expression Profiles 1.0 1.14058 HSPG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3176 UBIAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95626 CACNA2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36247 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE140965_1_v_4_mybpc3_human RummaGEO Gene Perturbation Signatures -1.0 null KCNF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59989 lateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76414 H3K4me1_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null Superior colliculus, motor related, intermediate white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.09153 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MSH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20958 prosomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09865 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53653 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.859136 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910745 GABPA_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19282 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 0.943122 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.58697 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-2326-SM-3LK7M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21738 GTEX-Q2AG-1026-SM-33HBW GTEx Tissue Sample Gene Expression Profiles 1.0 0.989399 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.4213 GSE246660_1_v_0_lmo3_human RummaGEO Gene Perturbation Signatures 1.0 null TCF7L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58384 GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.953086 D425 DepMap CRISPR Gene Dependency 1.0 4.03508 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FXYD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68972 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4UY-1626-SM-4AD55 GTEx Tissue Sample Gene Expression Profiles 1.0 0.869021 GTEX-XV7Q-1326-SM-4BRWM GTEx Tissue Sample Gene Expression Profiles 1.0 0.941495 MARCKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27275 MNT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39309 GTEX-S4UY-0526-SM-3K2AN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25528 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24207 ZNF606 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19304 ZNF384 ENCODE Transcription Factor Targets 1.0 null GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles 1.0 1.04477 disease GWASdb SNP-Disease Associations 1.0 0.023628 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.685 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25312 ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71222 SPINT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01411 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE238005_0_v_3_c9orf72_human RummaGEO Gene Perturbation Signatures 1.0 null Primary somatosensory area, unassigned, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00266 DPCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88457 SMARCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40559 NR4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98694 HOXC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47685 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01825 EEF1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47438 sequence-specific dna binding transcription factor activity GO Molecular Function Annotations 2015 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SPINT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50476 RAB18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84957 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.828112 H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-1226-SM-48FDQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02999 SKBR3 CCLE Cell Line Gene CNV Profiles -1.0 -3.21047 RAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64977 Superior colliculus, motor related, intermediate gray layer, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36534 GSE231720,GSE231724_2_v_1_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null NIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01513 GALNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23769 GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02564 Cells - EBV-transformed lymphocytes GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.842425 TTC9C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38091 NFYB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UPK5-2026-SM-4JBIM GTEx Tissue Sample Gene Expression Profiles 1.0 1.24383 RNA polymerase II cis-regulatory region sequence-specific DNA binding GO Molecular Function Annotations 2023 1.0 null GLYCTK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8059 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.21824 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.979009 RBM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43605 HAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52291 superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27062 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DCAF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75728 reticular formation of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04137 MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R3RS-0126-SM-3GIJL GTEx Tissue Sample Gene Expression Profiles 1.0 1.57922 regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null GSE99687_0_v_1_smad5_human RummaGEO Gene Perturbation Signatures 1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.31396 ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2251 intermediate stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.57708 regulation of rna biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828858 GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null GSE139016_0_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03172 H3K27ac_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FAM111B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0549 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BLVRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10303 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null nb4 HPA Cell Line Gene Expression Profiles 1.0 0.888852 MEX3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80532 YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10807 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6064 periventricular stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43204 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.27602 PMC12403153-pnas.2505021122.sd03.xlsx-ZNF93_TableS3-KZFP_ZNF93 Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02107 AK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40993 GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.38208 GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41731 NFYB ENCODE Transcription Factor Targets 1.0 null H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17675 GSE184087_4_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null Testicular germ cell tumor GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0699 hsa-miR-3689a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Brain - Caudate (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 1.37127 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ADIPOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78922 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19642 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 0.930682 SOCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13741 GSE202434,GSE202438_8_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09696 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.72063 H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF581 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80177 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE121824,GSE121826_0_v_3_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null OVMANA CCLE Cell Line Gene CNV Profiles 1.0 2.1756 B4GALT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60826 Gustatory areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0105 KHM1B CCLE Cell Line Gene CNV Profiles 1.0 1.49987 GRPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37587 rna metabolic process GO Biological Process Annotations 2015 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.7175 ACAA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21129 organic cyclic compound metabolic process GO Biological Process Annotations 2015 1.0 null NCIH1975 CCLE Cell Line Gene CNV Profiles 1.0 2.12087 GTEX-Q734-1926-SM-2I5EV GTEx Tissue Sample Gene Expression Profiles 1.0 0.925645 nucleus of diagonal band Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.901478 CDIPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71672 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13571 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56361 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3229 H3K9me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SF-0526-SM-3K2BC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936304 NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null EB2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.926093 NFKB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9301 PACADD188 DepMap CRISPR Gene Dependency 1.0 4.25322 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3791 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54934 GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948035 TRIP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76107 TAF1_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null F36P CCLE Cell Line Gene CNV Profiles 1.0 1.64384 GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01745 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-T2IS-1926-SM-4DM74 GTEx Tissue Sample Gene Expression Profiles 1.0 1.7795 CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.57064 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26324 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08269 GSE158632_2_v_4_oxyquinoline_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09932 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27946 GSE216540_0_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures 1.0 null Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.936638 GSE158834_10_v_9_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null NRDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1731 TMEM59L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54809 GTEX-X4EO-2926-SM-4E3JH GTEx Tissue Sample Gene Expression Profiles 1.0 1.53357 CLTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24811 CYTH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28421 GTEX-T2IS-0826-SM-4DM6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.32444 mantle zone of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55558 PMC9647903-13100_2022_279_MOESM9_ESM.xls-Human_KRAB-ZFPs-Information_of_all_human_KRAB-ZFP_genes_ZKSCAN7 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33071 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.49695 heterocycle metabolic process GO Biological Process Annotations 2015 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16955 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865072 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5855 GSE140997_2_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979829 RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUYS-0002-SM-47JXL GTEx Tissue Sample Gene Expression Profiles 1.0 1.48694 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21602 vagina GTEx Tissue Gene Expression Profiles 1.0 1.10799 GSE156923_0_v_3_rbmx_human RummaGEO Gene Perturbation Signatures -1.0 null Superior colliculus, motor related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68166 SU8686 DepMap CRISPR Gene Dependency 1.0 9.57236 GTEX-WWYW-0926-SM-3NB2Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.29747 MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27262 POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WASHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38145 GSE174498,GSE174500_5_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GSE155031_5_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null ETS1 ENCODE Transcription Factor Targets 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04959 GSE221327_8_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3214 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27484 GTEX-OIZG-0726-SM-33HBL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01949 Brain - Cerebellum GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.904161 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FTH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01361 EIF4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30403 GSE102870_11_v_0_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_12_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 2.93459 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE161800_0_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF705D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79553 GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2556 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.904653 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29757 COA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86185 FARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87493 nucleobase-containing compound biosynthetic process GO Biological Process Annotations 2015 1.0 null Acute Lung Injury_Lung Tissue_GSE1871 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.46994 GSE169356_0_v_3_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null alar plate of p1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36498 SPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48728 POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01746 FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27057 TCF7L2 ENCODE Transcription Factor Targets 1.0 null SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9536 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868901 MXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40061 GSE175787_5_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null PPM1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21869 anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00646 mantle zone of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92431 transcription, dna-templated GO Biological Process Annotations 2015 1.0 null GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.986705 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24801 GBGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12307 GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15471 GTEX-UPJH-0226-SM-3GADV GTEx Tissue Sample Gene Expression Profiles 1.0 1.08981 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.364 PBX3 ENCODE Transcription Factor Targets 1.0 null GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04967 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.89544 GSE151612_4_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null SIGLEC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65879 GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 RPL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92319 muscle GTEx Tissue Gene Expression Profiles -1.0 -2.10017 GTEX-SNMC-1226-SM-2XCFP GTEx Tissue Sample Gene Expression Profiles 1.0 1.08464 SAP30 ENCODE Transcription Factor Targets 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11667 THAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6352 lateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92337 A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.90897 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NPAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21727 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GSE182680,GSE182683_5_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00434 BECKER DepMap CRISPR Gene Dependency 1.0 2.11722 MYOCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3963 GABPA ENCODE Transcription Factor Targets 1.0 null HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45026 CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00179 SW1990 DepMap CRISPR Gene Dependency 1.0 2.38687 POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLA2G4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23469 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3667 PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-14_CD7_CD1a_DEG-DEG_L2FC_1_0_FDR_0_05_REL Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.990765 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.889139 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.02667 intermediate stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19796 GSE140997_10_v_1_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910745 Symplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.715 EBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75615 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE48812_2_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7469 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.19868 IRF2BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21002 anterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.862156 GTEX-Q734-1026-SM-48U16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.854657 H3K9ac_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158834_0_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null MPHOSPH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00714 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.50148 III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37198 RNA Polymerase II Transcription Reactome Pathways 2024 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RWSA-1426-SM-47JXA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.92041 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.993658 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.64593 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KLF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62201 GTEX-T6MO-0626-SM-4DM6P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1001 intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03377 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07403 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.910069 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.75997 DOK DepMap CRISPR Gene Dependency 1.0 3.9216 regulation of nucleic acid-templated transcription GO Biological Process Annotations 2015 1.0 null MFE296 DepMap CRISPR Gene Dependency 1.0 2.85786 GSE242333_0_v_2_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OIZH-1826-SM-2YUNP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.953973 OR2B6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85325 DAB2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52695 PMC12130184-12276_2025_1441_MOESM5_ESM.pdf-8-ZNF688_ZNF688 Rummagene Transcription Factor Associations 2026 1.0 null MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16816 SEPTIN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90206 BDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46586 GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08312 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53653 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17988 YY1_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K79me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3009 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0927 NOSIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69029 ZGPAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37265 POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98247 GTEX-U3ZN-1626-SM-4DXTZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.846514 GTEX-U3ZN-2226-SM-3DB88 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.883708 heart_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.47589 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X3Y1-2026-SM-3P5YM GTEx Tissue Sample Gene Expression Profiles 1.0 1.34821 EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0326-SM-3MJFY GTEx Tissue Sample Gene Expression Profiles 1.0 1.10206 C5orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12092 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31837 outer CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.830938 lymphnode_4b HPA Tissue Sample Gene Expression Profiles 1.0 1.27662 lateral preoptic nucleus, PO2 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03414 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18419 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SW 48 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.2498 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.842289 GSE151612_0_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PTPN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07299 GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8849 H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_0_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1178 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1067 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.970084 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47986 NOXO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89008 GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20226 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46922 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38607 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.71299 PMC11263707-41419_2024_6896_MOESM6_ESM.pdf-78-ZNF329_ZNF329 Rummagene Transcription Factor Associations 2026 1.0 null nucleus GO Cellular Component Annotations 2015 1.0 null GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89128 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.09728 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE175787_11_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SPTAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8119 MXI1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE245270_1_v_0_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null ANKRD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57371 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85452 GTEX-XBEC-1326-SM-4AT69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21348 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 0.99328 GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03422 mantle zone of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26698 POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.983733 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.80032 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11633 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28111 H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4935_KD_TP53_SRP067400 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE174498,GSE174500_3_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null KRT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.319 PMC4944136-srep28995-s2.xls-NOBOX-gene_NOBOX Rummagene Transcription Factor Associations 2026 1.0 null RANBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57626 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUCLG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81079 PEX16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55428 ZKSCAN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60027 NCIH1792 CCLE Cell Line Gene CNV Profiles 1.0 1.37046 RNASE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37727 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.831683 ZCWPW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36283 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SLC4A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03133 GTEX-SNMC-0826-SM-4DM66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34314 regulation of gene expression GO Biological Process Annotations 2015 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48724 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MRPS17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87542 GRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77852 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null FGFR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5289 Urinary bladder cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384 BMAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6874 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08714 GSE175787_8_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null YPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10176 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-2826-SM-3MJG8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12637 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE223893_1_v_9_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null ChIP_ASH2L_23239880 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.931114 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.881867 GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.48426 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28449 TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HTT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03549 GSE158834_10_v_6_palm_human RummaGEO Gene Perturbation Signatures 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48811 DUSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78949 MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE140997_10_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00374 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GSE77108_3_v_9_saha_human RummaGEO Drug Perturbation Signatures -1.0 null IDH3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69418 GGH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91359 L33 DepMap CRISPR Gene Dependency 1.0 2.47146 GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF479 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9709 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.56362 iPS-20b Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.960625 PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6D_mageckTFkoscreen_with_BATF3-gene_BATF3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.57128 CYB5R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18763 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAJI DepMap CRISPR Gene Dependency 1.0 2.03819 MAZ ENCODE Transcription Factor Targets 1.0 null GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMGXB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70038 YY1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WOFM-1326-SM-3MJFR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960968 GSE130401_4_v_0_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66089 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null tectal gray formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55393 H3K4me1_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ABCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2641 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.1165 upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55775 GTEX-PWCY-1426-SM-48TCT GTEx Tissue Sample Gene Expression Profiles 1.0 1.90532 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null bone marrow HPA Tissue Gene Expression Profiles 1.0 0.963568 GSE158834_2_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.845433 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.65557 JOSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17368 IGFBP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01027 RGP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83904 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41503 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 precommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08005 GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.983837 GTEX-WOFL-0126-SM-3MJG2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35303 1321N1 CCLE Cell Line Gene CNV Profiles 1.0 1.95468 TDRD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9205 GSE202434,GSE202438_4_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null PMC4889920-supp_gkw096_nar-03505-x-2015-File018.xlsx-Target_genes_per_GO_class-HKR1_ZNF875 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.18 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C15orf61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95299 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48461 IRF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-2126-SM-4B667 GTEx Tissue Sample Gene Expression Profiles 1.0 2.30726 KMRC20 CCLE Cell Line Gene CNV Profiles -1.0 -1.52333 GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1824 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08379 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928652 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883621 H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.829398 GSE95077_1_v_0_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02732 GSE193258,GSE193259_9_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85521 TP53I13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56761 Fetal Kidney Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.830375 CAND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89167 precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.118 LY6G5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17854 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7054 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882903 GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles 1.0 1.13935 GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998941 TBRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5025 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 Testicular germ cell cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 HILPDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39002 496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00077 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59285 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE216540_10_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.861147 UBE3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96452 MEG01 CCLE Cell Line Gene CNV Profiles 1.0 1.34199 cellular process GO Biological Process Annotations 2015 1.0 null GPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62208 Plasmodesma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.79 PMC12180575-FSB2-39-e70744-s001.pdf-84-GSC2_GSC2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UACC893 DepMap CRISPR Gene Dependency 1.0 2.58639 CBX3 ENCODE Transcription Factor Targets 1.0 null H3K9ac_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40013 A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.39147 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.948812 GTEX-OOBJ-1626-SM-2I3F7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4799-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8063 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.34572 CREBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5563 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18268 SH3D19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35436 ELF1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 0.984469 HT1197 DepMap CRISPR Gene Dependency 1.0 2.68041 MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.14151 TP53 JASPAR Predicted Transcription Factor Targets 1.0 null GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.958 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20469 GSE213410_0_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null INSIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95879 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null AFF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51668 GTEX-P4QT-2026-SM-3NMCJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.34844 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32539 NCI-H1944 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.86743 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.890567 RPL29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15908 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MFM-223 COSMIC Cell Line Gene CNV Profiles 1.0 2.12439 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35169 Ewing's sarcoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.678 GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41519 stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.842212 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3921 Sepsis_Splenocyte_GSE4479 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.74592 GSE175787_5_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92721 GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898693 GABPA_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null K562 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 2.04544 H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.853871 molecular layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.903252 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10906 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SEC16A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97598 DNASE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70778 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 1.71436 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 0.880634 GSE135244_0_v_1_trdmt1_human RummaGEO Gene Perturbation Signatures -1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.901039 OSC19 DepMap CRISPR Gene Dependency 1.0 2.04414 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04065 H3K9me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08076 DMKN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54404 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03223 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 bonemarrow_6c HPA Tissue Sample Gene Expression Profiles 1.0 1.69558 ASH2L-23239880-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE216273,GSE216292_14_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950318 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ZDHHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31269 GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE133763_0_v_2_chd1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-TMMY-1926-SM-4DXUU GTEx Tissue Sample Gene Expression Profiles 1.0 0.861852 TDOTT DepMap CRISPR Gene Dependency 1.0 5.32552 RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8109 REXO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63354 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96275 Anterolateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27332 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.02269 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19642 zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02834 TAF7 ENCODE Transcription Factor Targets 1.0 null GSE246660_1_v_0_glycerol_human RummaGEO Drug Perturbation Signatures 1.0 null ventrolateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3007 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0774 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96275 GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21118 GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.43826 H3K79me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CERS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57571 GSE245270_1_v_3_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null MGRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45355 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92006 eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_1_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08269 GSE158834_12_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null CCN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74936 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Unnamed_2_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958942 GSE216540_1_v_6_fulvestrant_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41891 superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2995 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14615 GP5D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17221 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03107 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08351 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PTMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26185 PFDN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86065 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null P4HTM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40196 GSE200099_3_v_1_honokiol_human RummaGEO Drug Perturbation Signatures 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.24251 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43944 A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.45149 Pancreatic ductal adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.046 Zinc finger, C2H2 InterPro Predicted Protein Domain Annotations 1.0 null MZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43193 GTEX-SNOS-0526-SM-4DM54 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44537 Perturb_1181_KD_CBFB_ERP128097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.67702 POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.921314 H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10298087-ijms-24-09830.pdf-2-ZNF25_ZNF25 Rummagene Transcription Factor Associations 2026 1.0 null ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.4304 lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5965 lateral terminal nucleus of the accessory optic tract, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32949 GTEX-TSE9-1226-SM-4DXTM GTEx Tissue Sample Gene Expression Profiles 1.0 0.82708 POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DGKZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03253 SNU620 DepMap CRISPR Gene Dependency 1.0 2.15821 GSE223893_1_v_10_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null Adrenal Gland GTEx Tissue Gene Expression Profiles 2023 1.0 1.38009 PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6C_mageckTFkoscreen_wo_BATF3-gene_BATF3 Rummagene Transcription Factor Associations 2026 1.0 null C1QTNF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35596 GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.981167 HRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93944 POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.38873 GSE151612_0_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.38145 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29288 GSE205163,GSE205164_3_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Left_Ventricle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.908762 GSE158834_1_v_6_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QLQW-1126-SM-2S1Q8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85952 GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.135 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96275 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15373_KD_BRCA1_SRP294453 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40646 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.971245 GSE196505,GSE196507_1_v_2_kdm2b_human RummaGEO Gene Perturbation Signatures -1.0 null GSE155031_5_v_3_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null GSE182680,GSE182683_10_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferior frontal gyrus, triangular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.974797 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29815 GSE221327_8_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null AU565 CCLE Cell Line Gene CNV Profiles -1.0 -2.49498 CCDC177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11927 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8575 GTEX-Q2AI-1526-SM-3GIJ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06593 nucleic acid binding GO Molecular Function Annotations 2015 1.0 null GSE175787_5_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null HNRNPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44762 H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE135514_2_v_9_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04502 SLC25A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56754 NCI-H838 COSMIC Cell Line Gene CNV Profiles -1.0 -3.15179 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32832 PIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52367 TOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56106 EP300 ENCODE Transcription Factor Targets 1.0 null PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-0826-SM-4B64N GTEx Tissue Sample Gene Expression Profiles 1.0 1.16971 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27707 lateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.61607 BEN CCLE Cell Line Gene CNV Profiles -1.0 -2.04376 TMEM139 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0277 GTEX-Q2AG-0126-SM-33HBV GTEx Tissue Sample Gene Expression Profiles 1.0 1.05194 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09387 MMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16545 GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852577 GTEX-XBED-0003-SM-47JWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.61035 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07327 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC12464728-HSR2-8-e71283-s008.pdf-374-FOXE3_FOXE3 Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PBX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PCSK9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37141 GSE182680,GSE182683_0_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0793 XPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30082 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.437 H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 BCL7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17247 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEYL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0443 ventral part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29723 GSE239844_1_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0326-SM-48U1O GTEx Tissue Sample Gene Expression Profiles 1.0 1.67463 KCTD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10243 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMRM-0926-SM-447BR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24993 GSE151612_4_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PPTC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9477 ATF1 ENCODE Transcription Factor Targets 1.0 null PMC11216188-peerj-12-17616-s013.pdf-320-ZNF681_ZNF681 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04287 GSE140997_4_v_3_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10967 Dorsal peduncular area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06832 YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1426-SM-2TF4H GTEx Tissue Sample Gene Expression Profiles 1.0 0.854273 Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57813 COMMD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52471 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null B9D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03284 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GNG14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14554 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IM9 DepMap CRISPR Gene Dependency 1.0 2.53546 GORASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58064 SUM52PE DepMap CRISPR Gene Dependency 1.0 2.39767 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRELD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49323 dna binding GO Molecular Function Annotations 2015 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89487 PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100466_PCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.20231 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.45448 pancreas HPA Tissue Gene Expression Profiles -1.0 -1.15275 PROKR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72705 pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.887033 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59838 IALM CCLE Cell Line Gene CNV Profiles -1.0 -1.33813 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28936 Platelet alpha granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.558 H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null substantia nigra, pars compacta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.984473 YIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85091 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96275 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8 MOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43707 GTEX-U8XE-1126-SM-3DB8W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.949533 POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SORT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2903 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain - Substantia nigra GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.08937 ARHGEF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59209 Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04065 GSE214212_2_v_0_chd6_human RummaGEO Gene Perturbation Signatures 1.0 null GSE145790_0_v_1_bruceantin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE182680,GSE182683_10_v_4_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null skbr3 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 HIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74489 Testicular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parasubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07654 H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE128054_1_v_0_myt1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13455 DOLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31791 ARL5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03287 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EXOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94216 SYVN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98884 hepg2 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 PMC11410964-41598_2024_71803_MOESM1_ESM.pdf-31-ZNF562_ZNF562 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE184087_2_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null PPARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19772 GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16523 POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37758 GSE131649_4_v_11_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60328 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C1orf122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68799 ALDH1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85785 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H4 DepMap CRISPR Gene Dependency 1.0 3.03247 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04297 OV90 CCLE Cell Line Gene CNV Profiles -1.0 -1.35793 DCP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93483 GUCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4847 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53653 GSE180789_1_v_0_hnrnpc_human RummaGEO Gene Perturbation Signatures 1.0 null MZ in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08512 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-2026-SM-3LK7U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29161 PMC10298087-ijms-24-09830.pdf-0-ZNF25_ZNF25 Rummagene Transcription Factor Associations 2026 1.0 null PMC6307949-jci-129-122819-s120.xlsx-SupplementaryTable9-ICR_Cohort_n_21_AR-V7_IHC_H-score_vs_gene_expression_FKPM_AR Rummagene Transcription Factor Associations 2026 1.0 null LHX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84531 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84778 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral posterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.243 GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.837479 H4C8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99858 CORL23 DepMap CRISPR Gene Dependency 1.0 2.97984 KAT2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.02351 GSE153907,GSE153908_0_v_1_azathioprine_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.45121 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05485 PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles 1.0 1.79237 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51794 GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35727 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93561 Agranular insular area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59285 GSE158834_1_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T6MO-0003-SM-3NMAG GTEx Tissue Sample Gene Expression Profiles 1.0 2.25428 Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.242 KDM5B ChEA Transcription Factor Targets 1.0 null regulation of nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null organic substance metabolic process GO Biological Process Annotations 2015 1.0 null lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04209 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 0.958893 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PARG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10388 GTEX-U3ZN-1226-SM-4DXUD GTEx Tissue Sample Gene Expression Profiles 1.0 1.03589 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69826 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2122 DepMap CRISPR Gene Dependency 1.0 3.0616 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.96803 GJA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01297 SP2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SP1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBC Pathway Commons Protein-Protein Interactions 1.0 null GSE168233_0_v_1_setdb1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE182680,GSE182683_7_v_11_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null NET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93778 RBM43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28695 GSE223893_2_v_10_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01849 JDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18501 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.884356 SARS-CoV NSP16_Day4_None_GSE49263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.38596 H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SQSTM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.21527 RMUGS CCLE Cell Line Gene CNV Profiles -1.0 -1.43024 Male reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.992029 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.974996 PMC8948606-7488708.f2.docx-6-HSFX1_HSFX1 Rummagene Transcription Factor Associations 2026 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null KLKB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21075 PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZBED2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5466 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27846 PK45H CCLE Cell Line Gene CNV Profiles -1.0 -2.0402 Heart - Left Ventricle GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.815966 GTEX-WY7C-2126-SM-3NB2R GTEx Tissue Sample Gene Expression Profiles 1.0 1.05022 icSARS CoV_30Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.843797 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84631 CKS1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45137 GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 0.875515 GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 2.07006 C19orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05957 LEUTX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78984 rectum_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.48288 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_11_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.9787 POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909568 superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2734 GTEX-UJMC-0326-SM-3GAE2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07875 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.82885 hl60 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 PMC6307949-jci-129-122819-s120.xlsx-SupplementaryTable9-UW_Cohort_n_41_AR-V7_IHC_automated_digital_scoring_vs_gene_expression_log2_CPM_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RTLS-0826-SM-2TF5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0253 GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28771 caudal group of intralaminar nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.990379 cation binding GO Molecular Function Annotations 2015 1.0 null GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834647 dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26477 496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07114 FAM234B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13901 RCOR1 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRL-1626-SM-2YUMU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870109 GTEX-SE5C-0426-SM-4BRUI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835466 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11354 ASRGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 regulation of nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 0.902904 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SE5C-0626-SM-2XCDV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17827 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890691 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.4186 496100597_HIP_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0118 CMTM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75634 RERFLCSQ1 DepMap CRISPR Gene Dependency 1.0 3.21371 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32866 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.22131 GSE216043_7_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43693 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-T6MN-0926-SM-32PLX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865418 FBXO28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2558 GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930069 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97222 b220.bcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.27498 ADGRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47199 MDFIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45583 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88226 GTEX-S7SE-0126-SM-2XCD5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.823982 GSE152246_0_v_1_dihydrotestosterone_human RummaGEO Drug Perturbation Signatures 1.0 null Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PRMT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05195 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVMANA DepMap CRISPR Gene Dependency 1.0 2.25666 CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.54904 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null adult testis HPM Cell Type and Tissue Protein Expression Profiles -1.0 -1.17363 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48895 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37016 EHMT2_KD_GDS4800_315_human_MDA-MB231 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4UY-0726-SM-4AD6X GTEx Tissue Sample Gene Expression Profiles 1.0 0.911498 HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 2.78989 H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37833 PPP1R16B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00698 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.64397 PMC12323057-13148_2025_1945_MOESM2_ESM.xlsx-17-Supplementary_Table_17_Overview_of_number_of_targets_genes_shared_with_THRB_THRB Rummagene Transcription Factor Associations 2026 1.0 null nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.149245 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31802 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null nucleic acid binding transcription factor activity GO Molecular Function Annotations 2015 1.0 null SP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PROX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48325 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 0.861889 GSE240468_3_v_2_nfyc_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null lymphnode_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.30439 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 2.65102 GSE190316,GSE190324_10_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null MZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08447 ZNF441 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54866 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51061 Cells - Cultured fibroblasts GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.948258 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PFSK1 DepMap CRISPR Gene Dependency 1.0 3.01865 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 PLXNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41489 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2564 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28338 neoplasm of the lung GWASdb SNP-Phenotype Associations 1.0 0.435234 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08231 GTEX-RN64-1626-SM-48FD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5595 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.2498 H3K4me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.43826 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_7_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WK11-2726-SM-3NMAQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.52407 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-WI4N-0626-SM-3TW8Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.912386 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14975 anterior pretectal nucleus, ventral core part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64992 HCT116 DepMap CRISPR Gene Dependency 1.0 13.113 H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55F-1726-SM-2TF4R GTEx Tissue Sample Gene Expression Profiles 1.0 1.30339 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVSAHO CCLE Cell Line Gene CNV Profiles 1.0 1.4839 intracellular part GO Cellular Component Annotations 2015 1.0 null GSE169356_0_v_1_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9976 TOE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45118 H2BC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32958 GTEX-OHPK-2526-SM-3MJH9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.891497 colonrectum_f HPA Tissue Sample Gene Expression Profiles -1.0 -1.21123 GSE158834_1_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.979633 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.42671 NDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47326 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 15489324-TableS2 GeneSigDB Published Gene Signatures 1.0 null A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45026 GTEX-RM2N-0826-SM-48FD3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26559 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882509 SLC25A39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15243 H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-P4QT-1526-SM-3NMCT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1551 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10079 RBL1_KO_GDS1932_739_mouse_Neurospheres GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30458 PRKCI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79979 cis-regulatory region sequence-specific DNA binding GO Molecular Function Annotations 2023 1.0 null SPI1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE182680,GSE182683_5_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE158834_10_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null RBM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6727 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.37744 GTEX-WYVS-1626-SM-3NM9R GTEx Tissue Sample Gene Expression Profiles 1.0 1.51122 PMC12180575-FSB2-39-e70744-s001.pdf-83-ZNF382_ZNF382 Rummagene Transcription Factor Associations 2026 1.0 null VKORC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69721 C17orf107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27304 GTEX-WFON-1626-SM-4LVMV GTEx Tissue Sample Gene Expression Profiles 1.0 0.873668 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.008 GTEX-P4PP-1526-SM-3P61M GTEx Tissue Sample Gene Expression Profiles 1.0 0.884188 GSE158834_1_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE245270_1_v_5_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.58123 GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 MZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13751 GSE223893_11_v_9_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null regulation of cellular macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null NDRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8666 8MGBA CCLE Cell Line Gene CNV Profiles -1.0 -1.79763 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.33974 GSE158834_7_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJYA-0001-SM-3NMDJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09221 ISCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44585 GSE176144_0_v_1_zfc3h1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MO-1426-SM-4DM73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67363 GSE203017_0_v_1_irs2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE174498,GSE174500_2_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YY1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.914882 Testicular cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.6598 WM115 DepMap CRISPR Gene Dependency 1.0 2.74571 Perturb_2815_KD_LSD1_SRP310243 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.951564 CABLES1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9927 GSE182680,GSE182683_5_v_9_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3613-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.981511 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09587 GSE158834_11_v_5_palm_human RummaGEO Gene Perturbation Signatures 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3009 GSE140965_2_v_4_mybpc3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE95077_5_v_0_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.68586 GTEX-S3XE-1126-SM-4AD4N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828188 RPL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26927 superficial stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32842 POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30399 PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932646 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 2.47483 GSE158834_11_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2208 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.06602 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null LRRC41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47236 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978984 GTEX-WHWD-0426-SM-3LK83 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.863913 Psoas_Muscle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.947952 cancer GWASdb SNP-Disease Associations 1.0 0.03589 PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04281 CEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09549 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C6orf120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39932 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles 1.0 2.2331 IQSEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63768 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GCFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86714 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87207 cell part LOCATE Predicted Protein Localization Annotations 1.0 null AGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 GTEX-SUCS-0002-SM-3NMAJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.841831 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5989 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4619 GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles 1.0 0.997039 hsa-miR-510 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 FUNDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83719 GTEX-N7MT-1926-SM-3LK5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.83162 A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.19787 CTSD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13223 U2OS CCLE Cell Line Gene CNV Profiles -1.0 -2.20312 hsa-miR-4695-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07636 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41425 H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE227698_2_v_1_g0s2_human RummaGEO Gene Perturbation Signatures 1.0 null FU97 CCLE Cell Line Gene CNV Profiles 1.0 1.8364 GSE233679_14_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null dorsolateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.8168 organ system cancer GWASdb SNP-Disease Associations 1.0 0.037379 PRR36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80395 GSE147876,GSE147877_2_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.90401 GSE258991_1_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27709 HCC1143 DepMap CRISPR Gene Dependency 1.0 2.05021 PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null GIPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25616 GSE188458_2_v_3_hydrogen peroxide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFG8-2226-SM-3GIL9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.89072 GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles 1.0 1.18353 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35169 lymph node HPA Tissue Gene Expression Profiles 1.0 1.04279 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00553 cell part GO Cellular Component Annotations 2015 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Fetal Heart Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.31089 H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4Q7-0003-SM-3NM8M GTEx Tissue Sample Gene Expression Profiles 1.0 1.04939 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7782 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ADSS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78001 neoplasm of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.251785 layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1644 GSE239844_4_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSK3_INHIBITION_GDS4043_459_human_MLL leukemia cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE74251_2_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19642 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26698 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3689c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 CREBBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30069 E2F6 ENCODE Transcription Factor Targets 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.10994 H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TMEM237 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17734 r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20236 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.092393 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.56343 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles 1.0 1.16495 SIN3A_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-0004-SM-46MWA GTEx Tissue Sample Gene Expression Profiles 1.0 1.12485 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.08528 HDQP1 CCLE Cell Line Gene CNV Profiles 1.0 1.98408 STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles -1.0 -0.838221 nucleic acid-templated transcription GO Biological Process Annotations 2015 1.0 null IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-2426-SM-3GILL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32297 GSE120612_4_v_3_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles -1.0 -0.954505 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.21139 RSPRY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65604 GSE234514,GSE234516_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-PVOW-0426-SM-2XCF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898851 GTEX-XQ8I-0926-SM-4BOOF GTEx Tissue Sample Gene Expression Profiles 1.0 1.08701 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DGCR6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84243 DNASE1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33262 HNRNPA0 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79512 H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10247733-41408_2023_863_MOESM2_ESM.pdf-578-ZNF69_ZNF69 Rummagene Transcription Factor Associations 2026 1.0 null ZDBF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61645 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64461 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54983 GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 TYSND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63663 B3GAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12046 LGALS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90024 mantle zone of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46653 MEX3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67507 GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 MBLAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18039 GSE158834_7_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16131 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66387 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null juxtacommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85477 POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null DNAJC28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59578 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05848 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978984 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35725 HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.842289 episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27097 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.978666 all GWASdb SNP-Phenotype Associations 1.0 0.028038 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null respiratory system cancer GWASdb SNP-Disease Associations 1.0 0.230945 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE182179_5_v_3_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null RNF182 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43698 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB Rummagene Transcription Factor Associations 2026 1.0 null cingulate gyrus, frontal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.918508 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27304 GABPA_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48936 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null GSE174498,GSE174500_2_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null TBCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15795 IPC298 CCLE Cell Line Gene CNV Profiles 1.0 1.43832 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33474 CEBPB ENCODE Transcription Factor Targets 1.0 null GSE206516,GSE206518_6_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null rna biosynthetic process GO Biological Process Annotations 2015 1.0 null JMJD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01342 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.882509 GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0757 CRELD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15538 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles 1.0 0.896219 Inflammatory myofibroblastic tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.122 VPS26C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44212 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55482 BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.54236 hsa-miR-4662a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.707 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.26175 CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GLIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99486 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles 1.0 1.31286 H3K9ac_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100331_TCx_probable Alzheimer's disease_TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02319 MRPS18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51246 GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 TRIM41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89181 GTEX-P78B-1826-SM-3P5YX GTEx Tissue Sample Gene Expression Profiles 1.0 2.08926 NCIH226 DepMap CRISPR Gene Dependency 1.0 2.16005 UMUC11 DepMap CRISPR Gene Dependency 1.0 3.2465 ASNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11926 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11625982-AJH-100-10-s001.pdf-60-POU2F2_POU2F2 Rummagene Transcription Factor Associations 2026 1.0 null PHPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79858 biosynthetic process GO Biological Process Annotations 2015 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.22447 MRPS18C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4664 Entorhinal area, medial part, dorsal zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14109 GTEX-XLM4-2026-SM-4AT4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB Rummagene Transcription Factor Associations 2026 1.0 null SEC23IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47641 IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-0326-SM-3DB8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13429 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HELA Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.32085 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10264 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07074 GTEX-PWCY-0526-SM-2I3ER GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06585 cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40416 TRIM28 ENCODE Transcription Factor Targets 1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904607 OTUD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20393 POU2F2 ENCODE Transcription Factor Targets 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11458898-41598_2024_73752_MOESM3_ESM.xlsx-TE_subfamilies-Supplementary_Data_2_KRAB-ZFP_primary_and_secondary_targets_of_the_TE_and_full-length_ERV_subfamilies_ZKSCAN7 Rummagene Transcription Factor Associations 2026 1.0 null ZRANB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39771 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30149 GOLPH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62112 Subiculum, ventral part, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52647 C1orf21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66507 GTEX-WYVS-1726-SM-3NMAY GTEx Tissue Sample Gene Expression Profiles 1.0 1.58806 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.86324 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HDLM2 CCLE Cell Line Gene CNV Profiles 1.0 2.37949 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.96866 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.87913 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963197 MIB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4065 SAFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12149 GSE202434,GSE202438_8_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GP2D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.18875 MZ in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37507 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZC3HC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84653 SPEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96379 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5444 NCIH838 CCLE Cell Line Gene CNV Profiles -1.0 -2.39936 GSE140997_2_v_1_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null Testis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.789508 PIGP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36757 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2012 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 130.474 abducens nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21913 PGAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91853 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855838 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 66.6209 PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Supplementary_Table_7_Transcription_factors_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null GSE158834_10_v_9_palm_human RummaGEO Gene Perturbation Signatures 1.0 null SW1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.38631 GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.118249 PCYOX1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83569 primary metabolic process GO Biological Process Annotations 2015 1.0 null subthalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17962 PNMA8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84107 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.937237 PFKM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78668 GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.869686 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null m1Lim (VL) part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43204 H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2759 USP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89891 GSE158834_0_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null 496100361_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03133 C80 DepMap CRISPR Gene Dependency 1.0 2.7922 ZNF257 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97295 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.956031 GTEX-XOTO-2126-SM-4B64U GTEx Tissue Sample Gene Expression Profiles 1.0 0.862447 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19996 JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.997995 H3K27ac_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-O5YT-0326-SM-32PKA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41823 ADNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46339 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZI-0626-SM-2XCEH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.976937 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09696 GSE158834_11_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28545 PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19996 BMAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29187 MZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36413 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE120612_7_v_1_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59693 MUS81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13617 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZN-2326-SM-3DB7W GTEx Tissue Sample Gene Expression Profiles 1.0 0.964646 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27874 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.61574 GSE158834_10_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null E2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.5444 SULT1C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02975 MMGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75102 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 GSE120612_6_v_1_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null PLAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91263 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19298 cervix uteri GTEx Tissue Gene Expression Profiles 1.0 1.12629 parafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847694 H3K27ac_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PERP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23623 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841021 GSE146612_1_v_3_amiodarone_human RummaGEO Drug Perturbation Signatures 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4355 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null basolateral amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02134 ACYP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09156 GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 DACT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15857 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35356 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.035453 PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7009 MDAMB361 DepMap CRISPR Gene Dependency 1.0 4.05792 GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30026 GTEX-PLZ6-0626-SM-3P61B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09862 Entorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10058 A172 DepMap CRISPR Gene Dependency 1.0 2.58603 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4141 CD99 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26641 SIN3A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE216043_10_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null LRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2312 Platelet alpha granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.062 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.970286 GSE130246_2_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.9117 GSE155031_6_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null GSE158834_10_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GSE140997_4_v_8_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -0.915012 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0726-SM-46MUW GTEx Tissue Sample Gene Expression Profiles 1.0 1.76039 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, unassigned, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15094 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.859136 SIX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92357 GSE140441_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null GSE174498,GSE174500_5_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.07734 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE216043_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12181 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 PLCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36402 KYSE410 CCLE Cell Line Gene CNV Profiles -1.0 -1.78185 PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34629 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01087 SW780 CCLE Cell Line Gene CNV Profiles -1.0 -1.3505 COLO-704 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08356 periventricular stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.81578 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06828 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11191 central layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51352 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884742 EHMT2_KD_GSE34925_693_human_MDA-MB231 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CCDC113 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50246 GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25363 ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE147366_3_v_4_med13_human RummaGEO Gene Perturbation Signatures -1.0 null LS123 CCLE Cell Line Gene CNV Profiles 1.0 1.53465 GTEX-QXCU-0008-SM-48FCH GTEx Tissue Sample Gene Expression Profiles 1.0 0.836873 GSE142210_2_v_6_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22872 SK23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.825051 posterolateral cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38451 GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles 1.0 1.35949 heart muscle HPA Tissue Gene Expression Profiles -1.0 -0.889391 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.936588 E2F4 ENCODE Transcription Factor Targets 1.0 null CST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38184 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922447 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7353 GTEX-PX3G-0526-SM-2I3EM GTEx Tissue Sample Gene Expression Profiles 1.0 1.08816 GTEX-XUW1-1526-SM-4BOOY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847171 PABPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91396 GTEX-XOTO-0526-SM-4B662 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44417 layer 5 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29288 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06155 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.61574 molecular_function GO Molecular Function Annotations 2015 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.961678 GSE48812_9_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HO1U1 DepMap CRISPR Gene Dependency 1.0 2.54798 GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03416 496100612_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3391 lymphnode_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.39653 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WYJK-0526-SM-3NM8Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.02723 UM-UC-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.879 hsa-miR-4722-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Generic Transcription Pathway Reactome Pathways 2024 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.71767 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.869889 RIMOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30658 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6537 PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null STK24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53897 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.23808 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 N-terminal protein acetyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.744 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07399 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Secretory granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.764 C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23845 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of metabolic process GO Biological Process Annotations 2015 1.0 null H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KHDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57491 GSE158834_10_v_4_palm_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null SW954 DepMap CRISPR Gene Dependency 1.0 2.09252 liminal alar domain of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30142 PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5978 CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COQ7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96846 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10648 MEST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.944466 INPP4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35425 F8A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52433 cellular aromatic compound metabolic process GO Biological Process Annotations 2015 1.0 null NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.4632 aromatic compound biosynthetic process GO Biological Process Annotations 2015 1.0 null organic cyclic compound biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.849427 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04675 CIPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05607 PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.04265 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TRUB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.44171 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null D542MG DepMap CRISPR Gene Dependency 1.0 3.18478 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-S4UY-0926-SM-4AD6O GTEx Tissue Sample Gene Expression Profiles 1.0 0.882967 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0726-SM-3GIJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.857133 Nerve - Tibial GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.965897 MZ in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.881026 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Gonadal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 CLDN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27842 PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.59248 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40089 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.96896 female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE85880,GSE85881_4_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null REEP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05389 Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51313 GTEX-U3ZN-2026-SM-4DXUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.27531 PMC11328671-jitc-12-4-s003.pdf-449-ZNF692_ZNF692 Rummagene Transcription Factor Associations 2026 1.0 null SLFN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71959 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14212 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 CEP152 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09932 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18832 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTF2B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CZIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46551 ALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10447 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE135312_1_v_2_bmpr2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06925 MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16975 METTL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78578 H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1419 DepMap CRISPR Gene Dependency 1.0 2.48839 GCSAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43574 ATP6V0A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07681 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SMAD5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1217 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Eye-adipocyte Tabula Sapiens Gene-Cell Associations 1.0 2.74365 CHST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65368 ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0347 macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4355 SRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12231 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU475 CCLE Cell Line Gene CNV Profiles -1.0 -1.82404 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1074 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01426 GTEX-R55E-0126-SM-2TC5Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.910848 Anterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03052 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39069 GSE205163,GSE205164_1_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05328 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GSE125014_6_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54593 JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 1.55462 GSE234043_0_v_1_abcb1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCAPG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99011 GTSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.454 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22986 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855246 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32098 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12468 EIF4E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94369 H3K27ac_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16433 mantle zone of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29754 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE171572_5_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06955 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54593 GSE182680,GSE182683_0_v_8_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null YY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0 fusiform gyrus, right, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.902352 GSE158834_12_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06749 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01831 mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33309 GPX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38251 nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0669 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAGEL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63785 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50178 PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34965 PBX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30541 HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-1226-SM-48TCH GTEx Tissue Sample Gene Expression Profiles 1.0 0.943171 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TMEM158 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01151 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.17408 GSE239688_4_v_1_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19124 hsa-miR-940 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9215 PK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49573 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23969 GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.843403 SMAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2763 subpretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.12968 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0762 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54361 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08897 GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01199 GSE202434,GSE202438_4_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFON-1126-SM-4LVMA GTEx Tissue Sample Gene Expression Profiles 1.0 0.970981 GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.851719 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68762 PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S4-Supplemental_Table_S4_Genes_commonly_upregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.042787 LRPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38537 GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SNOS-1226-SM-4DM5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.929682 SPSB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07183 RNA polymerase II transcription regulatory region sequence-specific DNA binding GO Molecular Function Annotations 2023 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-383-ZNF208_ZNF208 Rummagene Transcription Factor Associations 2026 1.0 null reticular formation of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07072 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.00553 POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE169152_3_v_7_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53128 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35159 MOSPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08974 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18616 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02697 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61759 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null regulation of macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null SARS-CoV MA15_Day4-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.34782 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66974 GTEX-RN64-0126-SM-2TC68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4412 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Superior colliculus, motor related, deep gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52984 bonemarrow_6a HPA Tissue Sample Gene Expression Profiles 1.0 1.10642 TEAD4 ENCODE Transcription Factor Targets 1.0 null GSE158834_12_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.831488 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WYJK-1026-SM-3NM8W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04722 GSE158834_7_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NPTXR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2339 TGFBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75271 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.874199 GTEX-XGQ4-0326-SM-4GIEE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00757 NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08714 CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07611 X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0652 Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04326 H2AFZ ENCODE Transcription Factor Targets 1.0 null Central amygdalar nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18981 APLP2_KO_GDS4414_534_mouse_adult cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ATG9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60037 lateral part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14377 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE102870_3_v_0_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null NCIH2172 CCLE Cell Line Gene CNV Profiles 1.0 1.77816 H3K79me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4P3-1326-SM-4AD6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.838139 GSE174498,GSE174500_3_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09587 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07142 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13489 GSE158834_10_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null ARVCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97977 NSUN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64496 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27986 PXDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25653 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0233 EFE184 DepMap CRISPR Gene Dependency 1.0 7.75023 PKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31307 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13593 GTEX-WEY5-0001-SM-3P61Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.38191 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05039 S100A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76555 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAP3K9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62736 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0032 H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66013 BLCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8817 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25122 Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29554 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 TMEM30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57858 GSE135030_3_v_2_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 TAFAZZIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93967 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TET1-21490601-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF556 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08784 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5X1-2526-SM-3GILC GTEx Tissue Sample Gene Expression Profiles 1.0 0.85221 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36599 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.933301 Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null P2RX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7402 POLR2A ENCODE Transcription Factor Targets 1.0 null PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Relationship_between_C2H2-ZNF_gene_expression_and_DNA_methylation_ZKSCAN7 Rummagene Transcription Factor Associations 2026 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59447 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13571 pretectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36096 GTF2B ENCODE Transcription Factor Targets 1.0 null H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K9ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null nucleic acid metabolic process GO Biological Process Annotations 2015 1.0 null FAM98C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96323 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 0.903915 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27893 SYNGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28487 CPNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.786 SLITRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87964 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles 1.0 1.20433 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 0.834304 GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IL27RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59068 regulation of cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null ventral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1106 GSE205163,GSE205164_1_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.31405 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.29431 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3734 NELFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18391 CIAO2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04757 RASA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81222 GTEX-XPVG-2526-SM-4B66D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885369 EM2 DepMap CRISPR Gene Dependency 1.0 2.66879 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.92637 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03359 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.80673 GTEX-XXEK-0326-SM-4BRVV GTEx Tissue Sample Gene Expression Profiles 1.0 0.915401 CHRNA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08401 GTEX-XUZC-0626-SM-4BOPG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.968426 biological_process GO Biological Process Annotations 2015 1.0 null GTEX-T5JW-2026-SM-4DM63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57485 Zinc finger, C2H2-like InterPro Predicted Protein Domain Annotations 1.0 null Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03927 TBC1D25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76973 dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33309 hsa-miR-1827 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.46934 GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43359 GTEX-R45C-0926-SM-3GAD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868807 TGFBR3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85664 TECPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20374 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 496100465_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01943 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.67755 GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19129 hsa-miR-4720-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ELK1::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.498 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32121 organic substance biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-R53T-1626-SM-3GAEW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 ventral reuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02584 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TFIP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81218 GSE216043_7_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13786 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.23141 SAAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29836 FOXO1_01_322 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62213 PHYH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 RCOR1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.4259 CELSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62219 GSE221327_1_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null YY1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05328 GSE182680,GSE182683_10_v_12_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE158834_2_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null TNNC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52374 SW948 DepMap CRISPR Gene Dependency 1.0 2.94266 Brain - Hypothalamus GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.895341 GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978405 GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null cellular macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null S100A16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94671 mantle zone of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39575 lateral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7032 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCIH520 CCLE Cell Line Gene CNV Profiles -1.0 -1.93508 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 WDFY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36178 NUDT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58209 intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87099 GSE232624_4_v_5_ethanol_human RummaGEO Drug Perturbation Signatures -1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.127 GTEX-POMQ-0626-SM-3P61E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846468 PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_26_ZKSCAN7 Rummagene Transcription Factor Associations 2026 1.0 null MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.71931 TMEM126A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91048 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64259 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0675 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GNPTAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64582 GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15829 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48811 GTEX-WH7G-0726-SM-3NMBM GTEx Tissue Sample Gene Expression Profiles 1.0 0.842196 GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964434 YPEL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92099 ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55E-1326-SM-48FCR GTEx Tissue Sample Gene Expression Profiles 1.0 1.28004 PMC12180575-FSB2-39-e70744-s001.pdf-84-ZNF671_ZNF671 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37115 TFDP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8216 GTEX-T8EM-1026-SM-3DB7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.19338 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1317 NCOA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68929 GTEX-R3RS-0626-SM-48FE1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.860136 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.053 PPARG JASPAR Predicted Transcription Factor Targets 1.0 null ASF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24605 GTEX-WRHK-1626-SM-3MJFH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.983582 GTEX-PWCY-1726-SM-48TD3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36393 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 0.838584 GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0772 PMC10679662-mmc3.xlsx-NC-D3-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null IGFLR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7619 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NUFIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35494 NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.62363 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.49238 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-832-ENSG00000160321_ZNF208 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41731 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles 1.0 2.77583 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMMY-0726-SM-33HBE GTEx Tissue Sample Gene Expression Profiles 1.0 0.962512 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.951262 HCC44 CCLE Cell Line Gene CNV Profiles 1.0 1.42817 MCHR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74625 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 IRF2BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4221 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0297 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63 Rummagene Transcription Factor Associations 2026 1.0 null retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15537 AARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65091 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NPIPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67303 intermediate stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65115 RIC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28674 HDAC1 ENCODE Transcription Factor Targets 1.0 null GTEX-PWN1-0726-SM-48TDR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.892768 MZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.92971 GSE120612_6_v_3_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null STK25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79896 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE205163,GSE205164_5_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 0.934257 SNU16 DepMap CRISPR Gene Dependency 1.0 9.31956 GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.987357 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE205729,GSE205731_2_v_1_tazemetostat_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.2498 urinarybladder_5c HPA Tissue Sample Gene Expression Profiles 1.0 1.40987 GSE147366_3_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null layer I of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05444 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TBX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68199 GTEX-XUJ4-1626-SM-4BONV GTEx Tissue Sample Gene Expression Profiles 1.0 1.23896 H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75972 regulation of primary metabolic process GO Biological Process Annotations 2015 1.0 null SETD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.58792 GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRR29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57714 GTEX-R3RS-1326-SM-48FE7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47066 GRPEL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06298 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158834_10_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE175787_4_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDIA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2039 GSE95077_1_v_4_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10372 LBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36953 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 0.828887 GTEX-U3ZH-1426-SM-4DXSR GTEx Tissue Sample Gene Expression Profiles 1.0 1.0435 GSE223893_2_v_9_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null EZR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76977 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.182 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33382 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Superior colliculus, motor related, intermediate gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56533 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.487 SIN3A ENCODE Transcription Factor Targets 1.0 null GSE158834_10_v_4_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 MZ in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.830146 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.87556 GTEX-OOBJ-1526-SM-3NB1Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.80323 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLEKHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89513 TMCO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46299 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 0.855052 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05926 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 Generic Transcription Pathway Reactome Pathways 2014 1.0 null hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.99957 C2orf69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97829 APLP2_KO_GDS4414_371_mouse_prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.44328 ROGDI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28944 GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EB1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.963224 RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB Rummagene Transcription Factor Associations 2026 1.0 null Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02139 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null GSE182680,GSE182683_0_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.75422 NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.33671 YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.2152 GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XY-1726-SM-46MVO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09072 ENDOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5815 BEX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21174 GSE213410_2_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures 1.0 null TULP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69858 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.6667 Gene Expression Reactome Pathways 2014 1.0 null chr19_23880993_GA_G_b38 GTEx eQTL 2025 1.0 1.67816 GTEX-XV7Q-2226-SM-4BRVY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861234 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 YY1 ENCODE Transcription Factor Targets 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -1.16793 GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100358_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.33464 Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30754 GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32811 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862269 YARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11578 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.18475 NMRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51222 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.941284 GSE143662_0_v_1_dcp2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-N7MS-0225-SM-4E3HO GTEx Tissue Sample Gene Expression Profiles 1.0 1.04341 LGR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36066 NACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7458 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889347 binding GO Molecular Function Annotations 2015 1.0 null hsa-miR-4642 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SP2 ENCODE Transcription Factor Targets 1.0 null layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70939 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40089 GSE142210_9_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null SHOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02157 Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08291 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10645 GSE119978,GSE180930_3_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Primary hematopoietic stem cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.841427 GTEx Ovary 20-29 vs 50-59 GTEx Tissue-Specific Aging Signatures -1.0 -5.2205 GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84929 NFYA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18686 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01523 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.841774 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909531 GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles 1.0 0.876183 GSE118077_1_v_8_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2564 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NR0B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7851 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028054 GSE74251_2_v_3_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.988015 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Periampullary adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.05 GSE188458_2_v_0_hydrogen peroxide_human RummaGEO Drug Perturbation Signatures -1.0 null Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86631 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69433 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8328 CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PBX3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0326-SM-2HMJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.991028 TDRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86232 BTBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7711 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -2.07549 PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Supplemental_Table_9_NEUROG3_bound_TFs_genes_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null CEBPB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CORO1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75024 GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17176 EPI-2461-1 (RPA2) NURSA Protein Complexes 1.0 null GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.46043 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.54754 GSE115395_2_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910994 intermediate stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51271 GTEX-SJXC-0126-SM-2XCFF GTEx Tissue Sample Gene Expression Profiles 1.0 1.48817 regulation of biosynthetic process GO Biological Process Annotations 2015 1.0 null LI7 DepMap CRISPR Gene Dependency 1.0 2.18761 PMC12180575-FSB2-39-e70744-s001.pdf-83-ZNF568_ZNF568 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEx SalivaryGland 20-29 vs 60-69 GTEx Tissue-Specific Aging Signatures 1.0 3.02032 skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.8353 GSE130396_1_v_6_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE158834_0_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null CAPNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05712 GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 2.83739 E2F4_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTRF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47325 EEF1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2911 ARL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81051 CSRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75291 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7259_KD_EP300_SRP193326 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MIER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23395 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null TET2_KO_GDS4287_430_mouse_CMP - bone marrow progenitor population GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null heterocycle biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 0.863528 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16293 GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21599 GSE223893_4_v_9_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null TCL1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6009 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03109 GTEX-PW2O-0126-SM-48TC8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.900226 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19012 RFX5 ENCODE Transcription Factor Targets 1.0 null GTEX-S32W-0926-SM-4AD5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.838968 karpas707 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 fat_8b HPA Tissue Sample Gene Expression Profiles -1.0 -1.04157