association	dataset	threshold value	standardized value
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00862
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Memory Performance	DisGeNET Gene-Phenotype Associations	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37902
C32	CCLE Cell Line Gene CNV Profiles	1.0	1.47477
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55243
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204443
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953232
COLO792	DepMap CRISPR Gene Dependency	1.0	2.69942
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anemia	GWASdb SNP-Disease Associations	1.0	0.354606
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91066
MCF7_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012157
K562_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201879
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7852
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.100444
MCF7_PF-573228_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197798
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05685
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124396
MCF7_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231374
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30111
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16542
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCO2	CCLE Cell Line Gene Expression Profiles	1.0	1.46268
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69479
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.42054
K562_Streptozotocin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0243917
K562_XAV-939_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179626
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1187
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991394
MCF7_Lomustine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235948
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05641
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991394
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2093
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0238035
MCF7_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0258156
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90412
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PECAPJ15	CCLE Cell Line Gene CNV Profiles	1.0	1.46535
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92049
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53428
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0301383
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27295
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11926
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5644
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.454387
C33A	DepMap CRISPR Gene Dependency	1.0	3.04978
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4899
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74559
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MCF7_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015679
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-3.13335
abnormal neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.473207
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11479_KO_Ring1_SRP321271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.79624
SMC3	ENCODE Transcription Factor Targets	1.0	null
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.02843
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31364
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.02922
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08611
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30111
H3K27me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PROKR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72705
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
F5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7296
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182285
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06219
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87587
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of body height	GWASdb SNP-Phenotype Associations	1.0	0.502664
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53074
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.470932
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73155
Dental caries	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
PMC11801220-NIHMS2038999-supplement-16.xlsx-Inh-MEF2C-gene_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.294715
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23105
CDK18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39105
H3K27me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30229
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62299
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12934
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0348736
K562_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185598
K562_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015594
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A115-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24545
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53392
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.238281
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0248983
ZNF33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01079
MCF7_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167294
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5976
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29489
K562_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184776
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19897
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.830726
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855452
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04985
MCF7_TMP195_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236566
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33042
MCF7_Bosutinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0121941
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159842
BECKER	DepMap CRISPR Gene Dependency	1.0	5.79247
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015973
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830707
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
SU-DHL-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal hemoglobin	GWASdb SNP-Phenotype Associations	1.0	0.515005
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
ACSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
K562_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192082
TBL1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04443
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86027
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10486
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93931
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32146
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.196
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26768
K562_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153945
GPR63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92711
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE96641_5_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
tooth disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31981
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00268
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190599
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21872
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98701
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33652
lung cancer	GWASdb SNP-Disease Associations	1.0	0.751374
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.572823
Pancreatic delta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23451
K562_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209172
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.125808
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05872
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8686
SLR21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45737
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eca-109 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33564
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61369
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08598
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3862
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3152
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94477
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161776
PLA2G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13283
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47017
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.29992
K562_Celecoxib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202771
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0817614
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.42767
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0214
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51873
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30806
MCF7_AT9283_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146934
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.142548
K562_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0362516
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57371
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50343
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28001
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06992
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04387
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46111
POLR1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3381
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49425
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36229
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12937
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31632
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01365
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.904696
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24104
MCF7_S-Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194091
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
MCF7_Barasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0275157
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22567
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22273
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60108
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
COR-L23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84062
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11913
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137118
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45414
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
K562_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186552
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884173
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
Prostate adenocarcinoma_PRAD_TCGA-HC-7212-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anorexia nervosa	GWAS Catalog SNP-Phenotype Associations	1.0	0.165905
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42581
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08167
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14537
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10389
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
MCF7_Sorafenib Tosylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117146
MCF7_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222127
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925942
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48867
MCF7_BMS-911543_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018754
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
eating disorder	GWASdb SNP-Disease Associations	1.0	0.430311
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.024531
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42125
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.176823
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77954
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3825
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02277
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57895
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.435234
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988778
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.747
ARNT	ChEA Transcription Factor Targets	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EFM-192A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.411526
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82108
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135006
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77216
SOX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21902
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KINGS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6394-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Patupilone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151762
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120801
nucleus	GO Cellular Component Annotations 2025	1.0	null
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18488
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70418
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09789
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76019
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95968
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65155
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991999
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.464
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.40361
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14583
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27428
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5553-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941932
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97842
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150793
MCF7_AICAR_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240433
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3039
CEP76	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84466
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166216
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89571
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERG	ChEA Transcription Factor Targets	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.662
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8987
K562_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0361166
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
K562_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0823158
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36496
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MCF7_Regorafenib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168914
MCF7_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0289054
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1344
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16676
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Altretamine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222321
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0278326
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
SNU46	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95023
MCF7_Nintedanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0240114
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	211.434
MCF7_Avagacestat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0274041
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
K562_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.122168
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92847
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
K562_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155645
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5213
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92985
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915409
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08028
congenital hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.606266
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179262
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50175
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01542
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.02914
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38787
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58959
K562_Ofloxacin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237718
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3999
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5112
Syndromic microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
immunologic hypersensitivity	GWASdb SNP-Phenotype Associations	1.0	0.327264
COLO800	DepMap CRISPR Gene Dependency	1.0	2.04712
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06655
MCF7_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210421
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3486
AR	ChEA Transcription Factor Targets	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77323
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32	DepMap CRISPR Gene Dependency	1.0	2.46013
LSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25088
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14871
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17854
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1724
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
TE159T	CCLE Cell Line Gene Expression Profiles	1.0	1.97146
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3303
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86103
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0346
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
EP300	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F7-01A-11R-A084-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016072
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225465
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21659
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35997
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.984
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29053
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7055
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11368
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52781
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	1.05629
MCF7_Carmofur_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0232131
MCF7_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0229234
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17727
Prostate adenocarcinoma_PRAD_TCGA-CH-5764-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
496100661_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56184
MCF7_EED226_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250147
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72617
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3928
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20101
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
MCF7_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249123
MCF7_XAV-939_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123665
developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Relationship_between_C2H2-ZNF_gene_expression_and_DNA_methylation_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75905
K562_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156314
MCF7_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222064
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09108
MCF7_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00958679
MCF7_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251888
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5691
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180125
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61696
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30991
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976556
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40181
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05518
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KDM5B	ChEA Transcription Factor Targets	1.0	null
HPAF-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.079638
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3589
MCF7_Droxinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198399
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Perturb_14982_KO_Setd1a_SRP330236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70188
HSC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75484
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60719
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48995
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850855
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.98959
MCF7_Cyclocytidine HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140342
obesity	GWASdb SNP-Disease Associations	1.0	0.971169
amyotrophic lateral sclerosis	GWASdb SNP-Disease Associations	1.0	0.554925
PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MC-1010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112414
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57754
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2294
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6831
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Valproic acid sodium salt_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126237
alcohol dependence	GWASdb SNP-Disease Associations	1.0	0.509492
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61827
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31644
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69583
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60827
MCF7_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173166
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212365
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2061
K562_JNJ-26854165_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242922
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
IRF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
Prostate adenocarcinoma_PRAD_TCGA-EJ-5542-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79308
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	1.37083
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1804
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61766
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Fiddlehead	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03426
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3286
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76627
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12193
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156812
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P4HA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73074
MCF7_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0344713
acute leukemia	GWASdb SNP-Phenotype Associations	1.0	0.385987
GATA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30153
hut102	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
MCF7_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176883
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.765
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84466
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80831
Perturb_4139_KO_Rai1_SRP074487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.17308
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04158
GI1	CCLE Cell Line Gene Expression Profiles	1.0	1.74179
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Navitoclax_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129947
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9577
MCF7_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144745
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72953
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56978
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-580-ZNF799_ZNF799	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189872
binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05225
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.194637
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07055
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00883
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04134
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08769
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983356
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15217
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.42183
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37884
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221483
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63961
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.330733
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233538
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49863
CUX1	ENCODE Transcription Factor Targets	1.0	null
MCF7_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117361
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90685
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33499
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82684
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81631
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04454
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
sirolimus_mus musculus_gpl7202_gse27784	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08767
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-205	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214598
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01513
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.149427
MCF7_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199534
CEDNIK syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01325
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	3.7554
EFM192A	CCLE Cell Line Gene Expression Profiles	1.0	1.44534
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSC3	DepMap CRISPR Gene Dependency	1.0	2.36813
MCF7_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129195
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.242966
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCC-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
MCF7_Andarine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171184
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	1.4483
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83371
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42659
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.75691
MCF7_SGI-1776 free base_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116191
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54729
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4172779-13048_2014_87_MOESM1_ESM.pdf-145-C9orf90_NAIF1	Rummagene Transcription Factor Associations 2026	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880199
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19073
UACC62	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53282
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	2.07411
MCF7_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154586
COASY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11307
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77095
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUO9	DepMap CRISPR Gene Dependency	1.0	2.27723
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84148
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.21707
SET2	DepMap CRISPR Gene Dependency	1.0	4.42048
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7729
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31829
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.288
K562_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016859
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61594
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
acute lymphocytic leukemia	GWASdb SNP-Disease Associations	1.0	0.768778
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56816
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53452
K562_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016049
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79228
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21332
MXI1	ENCODE Transcription Factor Targets	1.0	null
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.256762
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01462
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7033
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4976-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48165
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
MM1S	CCLE Cell Line Gene Expression Profiles	1.0	1.51427
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.198208
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857252
MCF7_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145128
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11049
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8482521-mmc13.xlsx-Phosphosites_12_hr_48_hr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.135475
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61897
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195775
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12712
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38935
MYL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4111
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEC1	CCLE Cell Line Gene Expression Profiles	1.0	1.4022
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36561
MCF7_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0397685
MCF7_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211808
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47476
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.254105
hypothyroidism	GAD Gene-Disease Associations	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70334
GCIY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49197
MYC_01_324	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.60875
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.56928
K562_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0245503
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.132688
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50079
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3622
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855452
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heschl's gyrus morphology	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89115
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835984
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78835
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.153122
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26554
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.131215
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bronchial disease	GWASdb SNP-Disease Associations	1.0	1.00808
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4866
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOMO1	CCLE Cell Line Gene CNV Profiles	1.0	1.74411
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33111
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.263244
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70457
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	2.49244
GSE84462,GSE84762_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6C_mageckTFkoscreen_wo_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35981
nucleus	GO Cellular Component Annotations 2023	1.0	null
MCF7_Momelotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175153
MCF7_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200892
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06447
MCF7_Hesperadin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136153
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81719
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.254105
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96371
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57257
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	3.28605
MCF7_BRD4770_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019057
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60007
MCF7_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210143
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19458
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015561
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23234
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0592
Pancreatic adenocarcinoma_PAAD_TCGA-F2-7276-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43524
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Iniparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0371967
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900789
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72783
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82981
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4983
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62715
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.84651
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3712
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.10032
kidney	HPA Tissue Gene Expression Profiles	1.0	1.25273
asthma	GWASdb SNP-Disease Associations	1.0	1.00808
USP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94783
K562_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197605
MYC	ENCODE Transcription Factor Targets	1.0	null
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81045
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0294045
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68237
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6902
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-a-Classification_of_camel_SON_basal_genes_-_transcription_factors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE227891_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast milk fatty acid composition (infant genotype effect)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
MCF7_Abexinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0107395
NR2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88045
MCF7_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139035
SOX2	ChEA Transcription Factor Targets	1.0	null
MCF7_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00633541
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09679
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14284
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04322
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9209
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0855
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953232
ZNF384	ENCODE Transcription Factor Targets	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02911
MCF7_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129952
K562_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0291119
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.202589
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188981
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4838354-supp_gkv1491_nar-01150-met-k-2015-File010.xlsx-ChIP-seq_defined_target_genes-PBX1_and_Notch3_common_target_gene_list_621_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82963
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40183
ZNF263	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20208
TBX4-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
K562_Maraviroc_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180601
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45145
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14733
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20042
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11741
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84835
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35736
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61854
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929422
MCF7_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175335
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48534
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50055
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MCF7_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0276717
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38029
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1276
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42239
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34028
MCF7_Luminespib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120904
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16676
Mesothelioma_MESO_TCGA-MQ-A6BQ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184531
K562_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260874
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO677	CCLE Cell Line Gene Expression Profiles	1.0	1.79366
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66803
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78984
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45701
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA5_GATA5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
AP1M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18684
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	3.81369
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07602
K562_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179883
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
M059K	DepMap CRISPR Gene Dependency	1.0	2.30612
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80721
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29264
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67699
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
MCF7_Fedratinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013401
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-PBX3-gene_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13434
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87267
body mass index	GAD Gene-Disease Associations	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38935
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29279
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57331
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
cancer	GWASdb SNP-Disease Associations	1.0	0.12385
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.144304
K562_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216908
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51264
PANC-08-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28859
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8651
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.941932
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
MCF7_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191112
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
HSPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3176
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.048641
MCF7_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142151
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2337
KYSE150	DepMap CRISPR Gene Dependency	1.0	13.7629
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
SNU761	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1465
ADPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5279
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34654
NCI-H1869	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15108
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18833
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09739
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.230541
SNU1079	DepMap CRISPR Gene Dependency	1.0	2.22732
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17565
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.650291
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60992
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Restless legs syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.3699
MCF7_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162308
ARHGEF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4853
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03299
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930756
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	1.84602
parkinson's disease	GWASdb SNP-Disease Associations	1.0	0.532681
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79345
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-1.29335
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38772
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11675
anorexia nervosa	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Fedratinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125917
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49146
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07909
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87559
MCF7_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0325424
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.301744
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T98G	CCLE Cell Line Gene CNV Profiles	1.0	1.46368
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85563
MCF7_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136259
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21889
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98452
specific developmental disorder	GWASdb SNP-Disease Associations	1.0	0.202746
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.77784
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4729482-pone.0146505.s001.xlsx-Sheet1-chRCC_positively_associated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00593
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28786
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6831
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00396
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60268
gamma-Glutamylcyclotransferase	dbGAP Gene-Trait Associations	1.0	0.457493
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Syndromic microphthalmia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9512
CHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80528
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	1.0	1.35195
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.100489
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_GSK-LSD1 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138104
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36695
vitamin d	GAD Gene-Disease Associations	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stroke	GWASdb SNP-Phenotype Associations	1.0	0.714303
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
PLB985	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78029
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88027
K562_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0391658
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.73138
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.118381
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04739
MCF7_Daphnetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152812
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76293
EW8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54796
MCF7_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173623
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71854
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80497
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81839
CHD1	ENCODE Transcription Factor Targets	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11744
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54238
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.08196
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11647
MCF7_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121418
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02993
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_18Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.01936
K562_Lomustine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01463
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00713
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.454387
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Supplementary_Table_7_Transcription_factors_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78695
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03595
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4858
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81591
bone marrow	HPA Tissue Protein Expression Profiles	1.0	2.24396
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
kidney	HPA Tissue Protein Expression Profiles	-1.0	-1.29335
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1315
Malignant peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74936
K562_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159779
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46546
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53796
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40379
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85906
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38933
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15174
cholesterol	GAD Gene-Disease Associations	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60864
GSE248858_5_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12355
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858533
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	3.2766
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82524
dental caries	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
SQ1	CCLE Cell Line Gene Expression Profiles	1.0	1.37742
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	2.38899
MCF7_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219416
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89872
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95164
MCF7_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126668
PMC10248560-tcr-12-05-1165.pdf-8-TP53_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	1.0	1.01682
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115692
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41237
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
substance dependence	GWASdb SNP-Disease Associations	1.0	0.202073
MCF7_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150695
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58959
thyroid gland disease	GWASdb SNP-Disease Associations	1.0	0.262778
MCF7_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133382
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.34658
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63925
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15106
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
developmental disorder of mental health	GWASdb SNP-Disease Associations	1.0	0.17092
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45148
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75318
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02048
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09154
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04739
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.0398
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8898
K562_UNC1999_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183263
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERG-21242973-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31721
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841684
PHF8	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858533
Vitamin D	dbGAP Gene-Trait Associations	1.0	0.378443
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.437
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08362
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33993
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12313
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1961
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3268
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42241
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15583
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
motor neuron disease	GWASdb SNP-Disease Associations	1.0	0.554925
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
abnormality of the thyroid gland	GWASdb SNP-Phenotype Associations	1.0	0.268045
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-PBX3-gene_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_CUDC-101_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.023692
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
teeth hard tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GFPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06405
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38674
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	1.04846
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873448
MCF7_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122439
Gene Expression	Reactome Pathways 2014	1.0	null
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84596
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62715
TFAP2C	ChEA Transcription Factor Targets	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3599
SNU-387	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Zinc finger, C2H2-like	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31273
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9398
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51074
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
CAS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43836
K562_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152237
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0324281
CCNYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34644
MCF7_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018016
K562_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0286675
K562_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0261179
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9927
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45326
K562_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0887473
leukemia	GWASdb SNP-Disease Associations	1.0	0.384562
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63852
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypothyroidism	GWASdb SNP-Disease Associations	1.0	1.00407
Nontraumatic osteonecrosis of the femoral head	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
MCF7_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126632
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
Perturb_4587_KO_Socs3_SRP074146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.68747
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904386
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31403
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04263
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91925
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16258
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177416
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76181
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57087
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06996
Acute Myeloid Leukemia_LAML_TCGA-AB-2996-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986045
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78551
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915422
MCF7_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142197
MCF7_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0268183
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0323568
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06381
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Unnamed_2_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50136
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95137
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
J82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BICR78	DepMap CRISPR Gene Dependency	1.0	2.00858
K562_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212864
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL4172 (NCRNA00153)	NURSA Protein Complexes	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22342
OSC20	DepMap CRISPR Gene Dependency	1.0	2.86887
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08768
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80324
MCF7_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248787
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75303
DEPDC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.71173
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64914
hemoglobinopathy	GWASdb SNP-Disease Associations	1.0	0.606266
PMC8482521-mmc13.xlsx-Phosphosites_48vhr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97502
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03299
MCF7_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239161
MCF7_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0300243
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35176
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05201
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13458
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903102
MCF7_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136554
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51036
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58192
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67569
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07042
Zinc finger, double-stranded RNA binding	InterPro Predicted Protein Domain Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
EGR1	ChEA Transcription Factor Targets	1.0	null
DLD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64074
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161495
OCILY3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38239
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86196
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56419
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133802
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.454387
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53558
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45821
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68605
MCF7_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140839
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RS411	CCLE Cell Line Gene Expression Profiles	1.0	1.89421
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2951
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0254134
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14221
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21935
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.117
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52631
Nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
FOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15006
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26831
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1679
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86877
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.078758
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11147
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.81282
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21688
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.00712
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171039
MCF7_Lomustine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150261
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51853
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5165-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49428
eating disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11246
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66434
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51724
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123222
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915422
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6056
K562_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148971
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.134683
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895877
abnormal motor neuron morphology	GWASdb SNP-Phenotype Associations	1.0	0.473207
Lake et al.Science.Ex8_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56669
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.214138
K562_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170953
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29127
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43505
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52878
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991999
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70421
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25626
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1189
MCF7_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159391
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98765
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.368031
IKZF2_01_137	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.83901
GRHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19482
K562_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132936
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39569
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.73801
endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
RH-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.81682
cSARS Bat SRBD_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.90582
20min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
K562_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197267
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Sirtinol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183648
MCF7_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152993
lymphoblastic leukemia	GWASdb SNP-Disease Associations	1.0	0.451272
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07839
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05248
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02116
PMC10331759-jgo-14-03-1307-supplementary.pdf-1-ZNF350_ZNF350	Rummagene Transcription Factor Associations 2026	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21739
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.122
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	2.00373
TE125T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04193
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841476
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886413
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51472
CCNT2	ENCODE Transcription Factor Targets	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54831
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41066
1min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992617
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89593
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	3.93357
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.59277
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9308
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68288
MCF7_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0362427
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	2.24396
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72328
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.09847
NB10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39784
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.194637
K562_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0264813
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137027
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80054
K562_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206726
hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
KDM5B	ENCODE Transcription Factor Targets	1.0	null
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.540309
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5691
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.242966
MCF7_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140307
METTL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8065
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10716
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72714
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184703
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899059
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14963
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13968
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43615
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.898713
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.015
496100458_FWM_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02268
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4532
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
MCF7_Tacedinaline_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189127
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Cholesterol	dbGAP Gene-Trait Associations	1.0	0.609439
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4877
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14479
SAP30	ENCODE Transcription Factor Targets	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47826
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06381
K562_Regorafenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193738
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23025
K562_Clevudine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015992
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97274
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09587
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_10_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6D_mageckTFkoscreen_with_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86265
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7987
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25626
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05678
MCF7_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171481
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
atrophy/degeneration affecting the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.473207
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19724
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858533
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09562
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37055
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74786
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15901
TNIK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15701
anorexia nervosa	GAD Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A7U0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	6.77241
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89857
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0924741
artery disease	GWASdb SNP-Disease Associations	1.0	0.120655
CTCF	ENCODE Transcription Factor Targets	1.0	null
OE33	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anorexia nervosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
PMC12464728-HSR2-8-e71283-s008.pdf-362-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
RPMI7951	CCLE Cell Line Gene Expression Profiles	1.0	1.77303
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26999
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7308
UBTF	ENCODE Transcription Factor Targets	1.0	null
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34025
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929353
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14032
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13276
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12281655-CPB-26-6-935_SD1.pdf-9-BARX2_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
RNA Polymerase II Transcription	Reactome Pathways 2024	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
immune system disease	GWASdb SNP-Disease Associations	1.0	0.102978
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81596
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2241
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32781
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2698
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.51751
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84653
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80505
K562_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147251
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11053
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.871915
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-2.08489
MCF7_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153454
GJA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01297
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38267
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18629
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61544
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_26_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157678
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11753
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49689
PMC6778131-41467_2019_12494_MOESM13_ESM.xlsx-Figure_S3b-BCL2-MYC_Day_75_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913282
K562_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172283
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88433
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826053
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68892
K562_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201996
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13583
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.06867
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	0.869084
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RSF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60181
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991394
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91906
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70815
K562_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154433
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91965
Perturb_11862_KO_Yap_SRP186725	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.30066
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91011
OE21	CCLE Cell Line Gene CNV Profiles	1.0	1.53159
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55686
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69553
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46709
MCF7_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171829
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Hypothyroidism	GWAS Catalog SNP-Phenotype Associations	1.0	0.057619
CXADR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76287
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	0.362606
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Aluminium levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3136
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76432
K562_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0232978
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of thyroid physiology	GWASdb SNP-Phenotype Associations	1.0	0.40409
K562_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139958
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07359
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
K562_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0383329
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4703
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.079
MCF7_BRD4770_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0555519
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55514
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57051
K562_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021387
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7543
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_BMS-265246_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233633
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.086731
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4721
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25703
MCF7_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0257993
MCF7_Meprednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141599
MCF7_Tanespimycin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130224
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04021
NOS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69046
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17751
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12734
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142471
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.66
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829408
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5639-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98764
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67242
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72283
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25209
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33914
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.202895
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69066
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09689
Ovarian cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
K562_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215468
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40242
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64867
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171517
MCF7_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146134
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51158
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04565
NCI-SNU-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21554
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14672
K562_ABT-737_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0388412
PMC12130184-12276_2025_1441_MOESM5_ESM.pdf-6-TFAP2E_TFAP2E	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138316
K562_Carmofur_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158689
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135983_0_v_1_dmba_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
acute lymphatic leukemia	GWASdb SNP-Phenotype Associations	1.0	0.666055
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60581
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41478
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.826
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fibronectin fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	7.39336
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47084
COPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69726
abnormality of b cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.406588
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4838354-supp_gkv1491_nar-01150-met-k-2015-File011.xlsx-Differentially_expressed_genes-Differntially_expressed_PBX1_and_NOTCH3_common_genes_under_GSI_FC_1_3_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Tozasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127566
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20488
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87499
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	2.03468
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89325
K562_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271879
hematological neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.175252
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12193
K562_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.02123
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47913
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.925864
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52877
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3854
RCC-AB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41394
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12282
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3692
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988778
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06778
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.198925
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84285
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33493
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986627
HMC18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4568
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972795
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58531
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.635554
K562_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149744
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83945
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.082573
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.120708
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03238
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00716
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
MCF7_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139677
SUZ12	ChEA Transcription Factor Targets	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.93927
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64904
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.063
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0421
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.689051
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40217
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.69855
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53651
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184138
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.903849
THAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89102
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884173
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.2662
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15032
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.06101
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35306
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MCF7_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0277665
K562_Raltitrexed_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180658
SLC25A27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92626
ITPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46247
K562_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180151
MCF7_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153913
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57152
K562_Decitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175973
K562_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250013
endocrine system disease	GWASdb SNP-Disease Associations	1.0	0.177354
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
HTRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49281
CPEB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06094
NTERA-2_CL_D1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48358
MCF7_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01536
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23599
asthma	GWASdb SNP-Phenotype Associations	1.0	0.886418
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870116
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09064
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155439
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
ES6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Generic Transcription Pathway	Reactome Pathways 2014	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04113
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.312569
lung disease	GWASdb SNP-Disease Associations	1.0	0.263244
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gene expression (Transcription)	Reactome Pathways 2024	1.0	null
MCF7_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136535
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
K562_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226827
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22583
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39745
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7897
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.66202
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34928
MCF7_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196504
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06341
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Pirarubicin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226374
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61854
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24565
Cholesterol, LDL	dbGAP Gene-Trait Associations	1.0	0.450271
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894618
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913927
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31332
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16294
Body mass index	GWAS Catalog SNP-Phenotype Associations	1.0	0.042592
GSE222500,GSE222501_1_v_0_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
MHH-CALL-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00931473
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49506
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017735
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.661313
Brain Lower Grade Glioma_LGG_TCGA-FG-A87N-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0268437
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839191
PCI-15A	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1586
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22297
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11588066-pnas.2410331121.sapp.pdf-84-ESR2_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
synucleinopathy	GWASdb SNP-Disease Associations	1.0	0.532681
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0112
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
MHH-NB-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.065051
A549_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154214
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07933
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198656
CAOV-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41651
K562_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019794
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13383
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22063
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9993
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42824
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2263
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35268
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
MCF7_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159376
CHD7	ENCODE Transcription Factor Targets	1.0	null
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40166
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38492
TSPAN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26883
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16121
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.363
NCI-SNU-5	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
motor neuron atrophy	GWASdb SNP-Phenotype Associations	1.0	0.473207
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53422
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypothyroidism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
GSE95771_0_v_2_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0381186
MCF7_Thiotepa_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145078
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1026
MOTN1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49491
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12137
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51787
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HEYA8	CCLE Cell Line Gene Expression Profiles	1.0	1.5614
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.732895
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.249465
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00404
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998143
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32458
WHSC1	ENCODE Transcription Factor Targets	1.0	null
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21688
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92579
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52275
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180426
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
GSE84462,GSE84762_0_v_7_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41372
specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Body dysmorphic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95564
IM9	DepMap CRISPR Gene Dependency	1.0	3.61239
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0096109
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58774
NCIH854	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58493
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human - Motor Cortex - Cross-Species Cluster - Layer 6 glutamatergic neuron, corticothalamic-projecting_2	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7417
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902351
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0290403
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63925
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51472
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90538
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
acute leukemia	GWASdb SNP-Disease Associations	1.0	0.768778
Superior colliculus, optic layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66438
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63961
C14orf119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46615
MCF7_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158767
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13255
MCF7_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167998
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07783
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45701
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04322
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22145
MCF7_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224875
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17967
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50424
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_ENMD-2076 L-Tartaric acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154221
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98337
JIYOYEP-2003	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04972
MCF7_FLLL32_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00982933
MFE319	DepMap CRISPR Gene Dependency	1.0	3.8788
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831796
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08401
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	2.11766
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136397
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24312
mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
kidney	GTEx Tissue Gene Expression Profiles	1.0	0.899616
RRP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21255
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78179
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129775
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36184
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23599
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.066558
K562_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118607
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90272
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35241
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06523
C18orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29955
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gamma-glutamylcyclotransferase	GAD Gene-Disease Associations	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.662069
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01487
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57073
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4309
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250775
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2255
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5803
MCF7_Pelitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218962
CAMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57927
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48629
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8994
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.958721
TCF4	ChEA Transcription Factor Targets	1.0	null
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.274483
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188599_1_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913927
SKN	DepMap CRISPR Gene Dependency	1.0	6.41914
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44993
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139547
MCF7_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220286
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65125
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911808
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855452
hematologic cancer	GWASdb SNP-Disease Associations	1.0	1.04846
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.099
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
K562_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147214
anorexia	GWASdb SNP-Phenotype Associations	1.0	1.00059
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20478
Mild Cognitive Disorder	DisGeNET Gene-Disease Associations	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0912
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6871
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9221
HCC1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tie2 kinase inhibitor_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211402
thyroid	GTEx Tissue Gene Expression Profiles	1.0	2.18241
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02148
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015903
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71153
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Zinc finger, C2H2	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUDHL1	DepMap CRISPR Gene Dependency	1.0	2.11589
MCF7_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200434
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1506
IgG glycosylation	GWAS Catalog SNP-Phenotype Associations	1.0	0.085234
Warsaw breakage syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
GNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3607
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94224
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156115
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1915	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	2.30902
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855452
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60405
K562_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0267351
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.099
abnormal immunoglobulin level	GWASdb SNP-Phenotype Associations	1.0	0.919744
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9496
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59186
NCIH2452	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75439
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6683-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.026539
MCF7_Meprednisone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254316
MCF7_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171421
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55166
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7706
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15401
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23752
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175074
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79283
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37727
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.8492
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
K562_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167182
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Veliparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170315
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95734
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913927
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
NCIH1755	CCLE Cell Line Gene CNV Profiles	1.0	2.50795
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38805
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60795
NACAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85549
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36967
K562_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149902
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64129
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.285323
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0299
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.33164
K562_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169217
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64242
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77132
MCF7_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138381
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.162705
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08524
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81654
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14429
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04682
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.415365
MCF7_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153693
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.015
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02405
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931448
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCB-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52056
MCF7_Resminostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01548
CMK	CCLE Cell Line Gene Expression Profiles	1.0	2.73552
K562_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166328
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.009
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02694
MCF7_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0326187
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cholesterol, ldl	GAD Gene-Disease Associations	1.0	null
GSE130396_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9759
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05246
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.606266
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.910457
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02405
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Disulfiram_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182046
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919947
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991999
HNF4A	ChEA Transcription Factor Targets	1.0	null
chr7_88693266_A_G_b38	GTEx eQTL 2025	1.0	3.4812
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0244
Stroke	dbGAP Gene-Trait Associations	1.0	0.178954
MCF7_PCI-34051_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015331
K562_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176332
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80036
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
K562_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155005
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990364
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAGLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24471
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23037
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
Mesenchymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10782
KMS18	CCLE Cell Line Gene CNV Profiles	-1.0	-2.38952
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6517
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07055
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188711
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04925
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
PMC8119428-41598_2021_89734_MOESM6_ESM.xlsx-Sheet1-Candidate_PORE_genes_potentially_bound_and_regulated_by_OCT4_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38685
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992342
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26187
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933798
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
MCF7_Fulvestrant_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115257
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65655
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30292
RL952	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32481
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10102
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
MCF7_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182637
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02479
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
Breast milk fatty acid composition (maternal genotype effect)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
MCF7_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0113286
SUDHL5	CCLE Cell Line Gene Expression Profiles	1.0	2.23236
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
K562_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142286
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.6138
MCF7_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131692
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
MCF7_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149645
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1576
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.618818
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UOK101	DepMap CRISPR Gene Dependency	1.0	2.00735
MCF7_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0345549
PEA1	DepMap CRISPR Gene Dependency	1.0	2.05005
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32965
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.290791
GSE62843,GSE64370_4_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20582
CALU6	DepMap CRISPR Gene Dependency	1.0	2.56567
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31733
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Mercaptopurine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163872
Brain Lower Grade Glioma_LGG_TCGA-CS-5390-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	3.15483
MCF7_BMS-265246_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161228
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20602
NCIH446	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67421
Frond	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
MCF7_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017171
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55921
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30772
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71666
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61996
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05103
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.242
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00451
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0234911
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12165
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
normocytic anemia	GWASdb SNP-Disease Associations	1.0	0.606266
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7488
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35559
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71716
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_XAV-939_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197845
MEL270	DepMap CRISPR Gene Dependency	1.0	2.90564
K562_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157399
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12958
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
OV-90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908387
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64407
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828434
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926206
HDAC1	ENCODE Transcription Factor Targets	1.0	null
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11002
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
abnormality of b cells	GWASdb SNP-Phenotype Associations	1.0	0.406588
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BN-01A-61R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272593
ERG-21242973-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LUC7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39472
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3918
MCF7_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163489
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154404
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13445
hypothyroidism	GWASdb SNP-Phenotype Associations	1.0	0.882984
K562_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156633
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955598
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09996
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73792
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34003
NOBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32551
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875258
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04482
Logical memory (immediate recall) in mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03922
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
K562_AG-490_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177316
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89581
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58879
GDM1	CCLE Cell Line Gene Expression Profiles	1.0	2.01667
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24453
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890409
K562_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171507
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43105
Lateral ventricle volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
stroke	GAD Gene-Disease Associations	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09739
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.97322
MCF7_BRD4770_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204247
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.370536
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05015
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3275
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41155
MAZ	ENCODE Transcription Factor Targets	1.0	null
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Supplemental_Table_9_NEUROG3_bound_TFs_genes_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_TGX-221_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233843
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75209
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58168
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7235
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76924
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65995
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15979
MCF7_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213055
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74395
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58646
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1698
LTF	MotifMap Predicted Transcription Factor Targets	1.0	null
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04801
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866359
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59643
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139222
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7585-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	1.0	2.04249
NCIH1573	DepMap CRISPR Gene Dependency	1.0	4.27661
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29182
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60391
FOXK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73934
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06801
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74332
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.668836
K562_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249249
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0761995
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65323
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Rigosertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0102791
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2081	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83356
OE33	CCLE Cell Line Gene CNV Profiles	1.0	1.79407
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	2.1345
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37981
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022675
MCF7_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0390082
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.84
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75009
MCF7_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223399
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53276
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
MCF7_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138814
Logical memory (delayed recall) in mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77878
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21014
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991394
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12015
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82346
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18742
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59769
MCF7_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142528
Prostate adenocarcinoma_PRAD_TCGA-CH-5765-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS513	DepMap CRISPR Gene Dependency	1.0	2.86724
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
MCF7_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0258701
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59625
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0157
ZNF331	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86301
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948674
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2422
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89674
H3K27me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00351
HS695T	DepMap CRISPR Gene Dependency	1.0	3.15689
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19793
HOXB7_01_170	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.53376
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35176
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00351
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48959
GSE206400_1_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56934
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944919
SCARB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99134
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24604
K562_EED226_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159801
MCF7_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162858
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.304606
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91576
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO783	CCLE Cell Line Gene CNV Profiles	1.0	1.6353
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41346
MCF7_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221222
MCF7_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123925
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57057
K562_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156202
PMC10809641-DataSheet3.pdf-438-ZNF80_ZNF80	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179546
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11157
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22111
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35559
Hypothyroidism	dbGAP Gene-Trait Associations	1.0	0.323533
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
COR-L279	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.096892
PMC9240038-41467_2022_31337_MOESM5_ESM.xlsx-Sheet1-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05153
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.36042
K562_Ki8751_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0252225
MCF7_AT9283_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01624
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5056
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60325
gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
EZH2	ENCODE Transcription Factor Targets	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24242
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31203
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03686
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05464
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60408
BICR16	CCLE Cell Line Gene CNV Profiles	1.0	1.44618
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26464
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8055
DMS53	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78538
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68389
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67372
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.92651
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32073
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97201
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26638
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59989
MCF7_PJ34_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132055
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71125
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87709
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13436
MCF7_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0292951
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Human - Fetal Development - L2 - Eye-Bipolar cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
K562_UNC0379_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0645704
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93857
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.330164
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6069
BMI1	ChEA Transcription Factor Targets	1.0	null
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901045
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
K562_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175311
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126845
PMC11801220-NIHMS2038999-supplement-14.xlsx-Inh-MEF2C-gene_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.855449
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82668
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06386
PGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54551
TTC642	DepMap CRISPR Gene Dependency	1.0	2.0181
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1859
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164706
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
K562_Ofloxacin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0456228
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4001
Peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53292
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.082407
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0262
MCF7_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0315132
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.825716
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
pancreas	GTEx Tissue Gene Expression Profiles	1.0	1.07842
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	7.06615
ZNF217	ChEA Transcription Factor Targets	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82568
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6812
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5375
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.076961
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67726
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11575
MCF7_Dasatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0104559
Restless legs syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56059
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50874
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0293627
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04387
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176814
BLOC1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3038
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62243
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29868
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76829
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53687
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90972
Human - Fetal Development - L1 - Bipolar cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_01_89	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58568
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.493
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.762459
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anorexia Nervosa	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900789
H3C10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01377
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95044
K562_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206888
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866029
RL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144287
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
MCF7_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211407
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04949
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12382
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56588
K562_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179013
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959555
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.309787
abnormality of humoral immunity	GWASdb SNP-Phenotype Associations	1.0	0.330164
MCF7_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0217453
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07359
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_Ellagic acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218884
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8084
K562_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203315
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90531
NCI-H1993	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33172
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
anorexia nervosa	GWASdb SNP-Disease Associations	1.0	1.14463
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5904-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
MCF7_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174178
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCCMPNST2C1	DepMap CRISPR Gene Dependency	1.0	2.43277
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3486
depression	GWASdb SNP-Phenotype Associations	1.0	0.371533
MCF7_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223906
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
HCT15	DepMap CRISPR Gene Dependency	1.0	2.19506
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38894
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7053-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abdominal symptom	GWASdb SNP-Phenotype Associations	1.0	0.311139
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32913
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3526
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18747
MCF7_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159658
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.47533
MCF7_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152311
OSBPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33498
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15222
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11718
MCF7_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200279
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42328
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92068
K562_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170908
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67931
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200482
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02808
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1468
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amyotrophic lateral sclerosis	GWASdb SNP-Phenotype Associations	1.0	0.473207
PC3	DepMap CRISPR Gene Dependency	1.0	2.12575
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64259
ERBB3_knockout_239_GSE32129	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.594258
K562_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271046
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.37658
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
Anorexia nervosa	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.281
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
leukemia	GWASdb SNP-Phenotype Associations	1.0	0.268796
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37088
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81601
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85741
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EPLC-272H	COSMIC Cell Line Gene CNV Profiles	1.0	2.39327
mania	GWASdb SNP-Phenotype Associations	1.0	0.540309
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43502
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82184
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77738
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_XAV-939_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113044
K562_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189262
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCO2	DepMap CRISPR Gene Dependency	1.0	2.16567
EID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75348
KP1N	DepMap CRISPR Gene Dependency	1.0	3.17539
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAFA-gene_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
Generic Transcription Pathway	Reactome Pathways 2024	1.0	null
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.150596
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0541
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62084
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21889
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8888
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	1.36329
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Cediranib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130942
Cervical cancer	GWAS Catalog SNP-Phenotype Associations	1.0	0.042592
Warburg micro syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
MCF7_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163329
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873448
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53354
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3064
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.818753
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64881
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26335
MCF7_Lenalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019658
MCF7_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185603
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07198
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anorexia Nervosa	dbGAP Gene-Trait Associations	1.0	0.443956
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65616
MCF7_Ofloxacin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133349
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Lapatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204679
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1332
SNU1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67734
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1677
MCF7_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012859
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988624
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
MCF7_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219747
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95993
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37196
MCF7_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284285
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59988
MCF7_AG-14361_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0266937
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4365
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142654
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02151
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842987
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010831
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.25083
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04879
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	7.18646
MCF7_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0320012
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32056
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7605
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24503
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.94414
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MCF7_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150537
MCF7_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203526
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212248
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.29335
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45211
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11422
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99645
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17274
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84466
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04441
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11211
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26264
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	211.359
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139407
CELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08673
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181141
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0273331
K562_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284827
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17405
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CCF-STTG1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAFA-gene_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0105859
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86387
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
K562_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178165
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20121
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07638
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.33164
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8056