association	dataset	threshold value	standardized value
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844514
Blood Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65323
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.21983
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94804
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04395
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80549
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
hsa-miR-33a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4432
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67887
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18578
Sarcoma_SARC_TCGA-DX-AB2Z-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67411
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.14577
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905807
Secondary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
Lymph_Node-cd4-positive alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	6.21812
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83885
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79335
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4173-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68082
ZNF219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22365
NCI-H2085	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15345
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
FGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57037
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5948
HCC1419	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
hsa-miR-3922-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3613-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41986
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45295
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5886
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60874
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4165
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2615
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.044458
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.071
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933262
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22977
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44222
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0282
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01764
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7	DepMap CRISPR Gene Dependency	1.0	10.4783
TCFL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68842
SBC5	CCLE Cell Line Gene Expression Profiles	1.0	1.70134
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55272
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H441	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_10_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
PGR-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90616
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50518
Lung adenocarcinoma_LUAD_TCGA-97-8172-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1733_OE_Wwtr1_SRP280028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.2785
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81654
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3173-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927808
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48975
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03732
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06055
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18135
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62845
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0755
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30153
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripartum cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52089
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Diastolic blood pressure (cigarette smoking interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.61549
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.0551
Disease Susceptibility	HuGE Navigator Gene-Phenotype Associations	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
fallopian tube	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836151
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31292
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H4C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36844
GSE211963_0_v_3_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Androgen insensitivity syndrome_Fibroblast_GSE3871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43142
hsa-miR-3149	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
hsa-miR-654-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859214
Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.43433
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72244
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.134
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.872571
Brown vs. black hair color	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.58982
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08946
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
essential hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CI1	CCLE Cell Line Gene Expression Profiles	1.0	1.54549
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.83
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72413
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80324
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72007
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the ovary	GWASdb SNP-Phenotype Associations	1.0	0.282883
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.37193
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7295
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51021
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFE319	DepMap CRISPR Gene Dependency	1.0	2.58917
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
hsa-miR-1323	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95014
D-247MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Supplemental_Table_9_NEUROG3_bound_TFs_genes_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866006
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1971
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54834
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-774-ZNF705A_ZNF705A	Rummagene Transcription Factor Associations 2026	1.0	null
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5895
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910646
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0421
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
PMC12021535-CPH4-15-e70011-s001.xlsx-S21-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.855549
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98769
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02227
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
abnormality of female internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.159416
Spleen-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.541912
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3924-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.782
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2267
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14718
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.7244
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8774
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37156
hypertension	GAD Gene-Disease Associations	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-520	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dexamethasone_homo sapiens_gpl570_gse33135	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
hsa-miR-519c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Lymph_Node-regulatory t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.25001
MYO1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73641
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.906
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.052897
Systolic blood pressure x alcohol consumption interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.02218
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845277
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4715-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
TRIM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14136
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07445
Lung adenocarcinoma_LUAD_TCGA-MP-A4TH-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95052
TUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53095
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845871
Perturb_1745_KO_Tet2/Tet3_SRP063091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.3334
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67788
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06849
gastrointestinal inflammation	GWASdb SNP-Phenotype Associations	1.0	1.5645
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51462
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07012
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50116
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58103
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
hsa-miR-96	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82484
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04559
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836023
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14073
GSE126402_5_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27473
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51475
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC0504	DepMap CRISPR Gene Dependency	1.0	4.51723
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.743226
GADD45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72031
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96918
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-4667-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
cancer	GWASdb SNP-Disease Associations	1.0	0.039949
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85191
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69487
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
spleen	HPA Tissue Gene Expression Profiles	1.0	0.908791
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57434
Melanoma	CTD Gene-Disease Associations	1.0	2.88009
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96251
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08647
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83057
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6325
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPT11	CCLE Cell Line Gene Expression Profiles	1.0	1.38552
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16183
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4745
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5249-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32296
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66715
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreatic cancer	GWASdb SNP-Disease Associations	1.0	0.650844
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22237
Protein phosphatase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.62753
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
appendices_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.886621
FEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47126
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
hsa-miR-500b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82158
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40394
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59491
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94529
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17717
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6203
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59692
15489324-TableS2	GeneSigDB Published Gene Signatures	1.0	null
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-NFATC3_mod_NFATC3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64056
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830907
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations	1.0	1.13226
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39368
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62798
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
Response to antipsychotic therapy (extrapyramidal side effects)	GWAS Catalog SNP-Phenotype Associations	1.0	0.057619
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11026
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GS-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6572
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92884
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PIGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71601
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09484
GABPA_01_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.99025
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40426
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
hsa-miR-3133	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76955
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6545
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87988
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	2.16715
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.331
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
hsa-miR-4269	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
HCC-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831232
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02345
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839942
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
ERV3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34765
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5527
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24923
Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
PMC5352226-elife-20488-fig4-data5.xls-tfnames-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33178
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5264
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
premature ovarian failure	GWASdb SNP-Phenotype Associations	1.0	0.532619
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.861654
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20041
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.136733
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94291
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
H4K20me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-571	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36269
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23442
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
hsa-miR-135b	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839401
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30624
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25133
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.452
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58431
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894963
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16159
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05062
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24594
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6D_mageckTFkoscreen_with_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903321
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1781	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38224
TPCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99667
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90231
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
MUTZ5	CCLE Cell Line Gene Expression Profiles	1.0	1.43676
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30909
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-STAT4_mod_STAT4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15073
KMBC2	DepMap CRISPR Gene Dependency	1.0	2.25284
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
SNU1197	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47478
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856417
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85888
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99297
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886904
OSC19	DepMap CRISPR Gene Dependency	1.0	2.81709
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45239
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26072
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50344
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860449
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09783
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
hsa-miR-34a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2718
LAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99289
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88738
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92723
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74467
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5222
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5449
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12844
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61791
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23562
GSE211744_2_v_4_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848821
intestinal disease	GWASdb SNP-Disease Associations	1.0	0.465282
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.001722
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10809641-DataSheet3.pdf-438-ZNF80_ZNF80	Rummagene Transcription Factor Associations 2026	1.0	null
Medication use (calcium channel blockers)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10969
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92719
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE143643,GSE143644_3_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04868
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83651
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02834
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89137
hsa-miR-3973	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933179
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968465
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08569
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63008
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51647
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14098
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.7244
ZNF324B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38162
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91906
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61598
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	3.40772
Perturb_7930_KD_ZCCHC8/ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.52155
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33015
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6889
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85873
GSE152379_0_v_4_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4506	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912716
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7082
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97212
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866905
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2984
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Unnamed_18_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830193
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0845
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70456
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ovarian disease	GWASdb SNP-Disease Associations	1.0	0.429429
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25179
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	3.61205
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838343
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.7244
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99739
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50818
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-109-IPF1_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976008
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.193297
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872664
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal coat appearance	IMPC Knockout Mouse Phenotypes	1.0	null
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17161
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5007
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.947349
HCC1954	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
GSE114992,GSE114993_0_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07062
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45262
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68263
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Platelet distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5301
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61914
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05662
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4659b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE143643,GSE143644_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24214
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.257
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91918
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10825
LC4-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69841
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UM-UC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4641-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39981
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03546
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0545
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Myopia	dbGAP Gene-Trait Associations	1.0	0.323533
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Z-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1178	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Unnamed_2_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01786
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0083
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1105
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95993
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MTRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48474
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.092076
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.048511
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3456
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3387
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05511
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	2.1547
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-548d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0831
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15996
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-3145-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16747
SESN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93288
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77425
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
hsa-miR-298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-142-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.970972
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56565
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Down_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92783
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09806
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19223
GSE103124_1_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KO52	CCLE Cell Line Gene Expression Profiles	1.0	1.52853
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43372
SUIT2	DepMap CRISPR Gene Dependency	1.0	3.08782
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-519b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
Perturb_7959_KD_ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.93328
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28775
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74386
Ankylosing Spondylitis	DisGeNET Gene-Disease Associations	1.0	null
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4148-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08253
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84781
PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7790_KD_UBL5_SRP044298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.204426
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
KPL1	CCLE Cell Line Gene CNV Profiles	1.0	1.99136
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3997
KE37	CCLE Cell Line Gene Expression Profiles	1.0	1.79959
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69737
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57101
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05824
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13991
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29934
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03893
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.46932
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4733-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19S-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
neoplasm of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.55536
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.894262
Perturb_17419_KO_Suz12_SRP168570	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.6272
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22364
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the mouth	GWASdb SNP-Phenotype Associations	1.0	0.146591
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.041854
ZNF821	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92802
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3923
Systolic Blood Pressure Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5675-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
PMC7786291-Table_1.xlsx-Table_S1-Supplementary_table_1_ETV7-related_genes_in_the_TCGA_SKCM_data_set_ETV7	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal skin coloration	MGI Mouse Phenotype Associations 2023	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7468
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21515
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88644
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.846987
hsa-miR-2113	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824274
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OLFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55714
TAL1	ChEA Transcription Factor Targets	1.0	null
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
ZNF471	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49761
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.51502
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961314
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1623	CCLE Cell Line Gene Expression Profiles	1.0	1.34929
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17893
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98754
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.29632
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
SYNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90164
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ZFP69B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34106
hsa-miR-2277-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.0194
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11113
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
pancreatic adenocarcinoma	GWASdb SNP-Phenotype Associations	1.0	0.55536
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.059
hsa-miR-4690-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09883
OTUD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03718
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41971
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30347
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Perturb_2123_KD_LSD1_SRP280081	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.20538
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Zinc finger C2H2-type/integrase DNA-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.936015
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47075
hsa-miR-487a	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Supplementary_Table_7_Transcription_factors_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28275
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43412
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91972
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72288
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37566
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05508
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86576
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36316
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11457_KO_Ezh2/Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.18645
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30605
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
PANX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10941
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9347
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5571
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872984
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52515
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88272
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymph_Node-naive thymus-derived cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.81422
PMC10311050-mmc2.pdf-46-LMX1B_LMX1B	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827474
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4014
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92793
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15223
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93495
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	2.56415
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16578
CHEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88769
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998785
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14492
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN_KO_GDS4205_294_mouse_B lymphoid cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RALGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29013
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57904
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.174
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S1_LMS_SNV-Supplementary_Data_1_Most_Recurrent_Non-Synonymous_Point_Mutations_in_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48927
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17326
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839718
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06251
Perturb_16827_KO_MLL4_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.8085
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936877
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56228
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41258
Perturb_7807_KD_CSTF2_SRP071700	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.23643
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16893
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33253
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LXF289	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54802
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Pancreatic Neoplasms	dbGAP Gene-Trait Associations	1.0	0.045356
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.86125
HT-144	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
SK-OV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996587
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05641
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC2	ENCODE Transcription Factor Targets	1.0	null
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19728
hsa-miR-615-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-495	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	6.00105
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87508
hsa-miR-4735-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKBIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80646
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6395
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Skin-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0736191
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55629
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51092
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62047
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH661	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4934
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98876
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835662
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831488
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43253
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838536
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45436
PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-ZFP_genes_expression_vs_methyla-Relationship_between_C2H2-ZNF_gene_expression_and_DNA_methylation_ZKSCAN7	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84393
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.35148
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67041
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914076
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Medication use (beta blocking agents)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858861
hsa-miR-132	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HCV_8week-No IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.63048
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
ASPSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92256
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12685
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
hsa-miR-4446-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16465
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35569
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.441916
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35686
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03092
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.95
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80749
GSE140651,GSE140653_3_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28202
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
Zinc finger, C2H2	InterPro Predicted Protein Domain Annotations	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2941
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18225
all	GWASdb SNP-Phenotype Associations	1.0	0.054718
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the female genitalia	GWASdb SNP-Phenotype Associations	1.0	0.159416
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17029
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4LX-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840848
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11003
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1279
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
Immunoglobulin complex, circulating	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
HOXD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98189
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80306
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26956
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00566
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26109
SUZ12	ChEA Transcription Factor Targets	1.0	null
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7789_KD_UBL5_SRP044298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6201
Perturb_1245_OE_MYC/BCL2/BCL6_SRP376326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.92407
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83054
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00926
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31537
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05941
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.374155
Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65099
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12007
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GCIY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63976
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82857
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15631
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51309
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960002
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02051
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53395
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10225
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.187439
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	3.1861
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2612
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.55355
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-11A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21377
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26365
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77581
hsa-miR-4327	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80389
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	2.7004
NCIH358	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80257
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47091
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17771
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZKSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84941
Perturb_1182_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.6576
GTEX-P4QS-0626-SM-3NMD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90102
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
HEL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37235
functional abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.359285
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02939
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39481
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.902748
hsa-miR-3916	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93167
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77879
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882816
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13856_KD_CDC27_ERP133806	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.11953
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
placenta	HPA Tissue Protein Expression Profiles	1.0	0.98558
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11463
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9659
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4916-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30527
PMC9452874-40246_2022_406_MOESM3_ESM.xlsx-ARM_HT_ST18_Replicate_Evangelou-Supplementary_Material_X_Summary_statistics_for_known_HT_GWS_signals_in_our_dataset_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873426
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52745
hsa-miR-203	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26919
Perturb_7785_KD_MTREX_SRP043962	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.33187
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33367
hsa-miR-4517	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870168
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12987
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE218500_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
NYNRIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31919
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924427
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34827
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62894
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5556-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stroke	GAD Gene-Disease Associations	1.0	null
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22316
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74252
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5162
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35499
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-4645-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4994
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38736
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4145
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26293
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32323
PMC7608835-aba3058_Table_S3.xlsx-162_H2Aub-RING1B_yesFLI1-Genes_containing_RING1B_EWSR1-FLI1_H2Aub_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-802	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_7730_KD_HNRNPC_ERP001458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01718
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70242
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
PMC7781436-NIHMS1653552-supplement-Table_S2.xlsx-Variably_expressed_TFs-ZNF878_ZNF878	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.885695
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8671-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45092
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922932
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFKBIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8751
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4C_BATF3_downreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11499
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.104123
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9979
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98768
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91669
WDR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22377
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906267
hsa-miR-548j	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31716
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99349
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36363
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.438
CAMK2D	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93107
PURG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96995
female reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.233838
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56161
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.712
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846885
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.4533
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
NCIH520	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36328
hsa-miR-519a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.848142
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.80453
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-x_TFEB_KOcon_VS_WTcon_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57847
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76349
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21937
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6823
hsa-miR-4700-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
hsa-miR-4523	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.191712
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99853
hsa-miR-4733-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
hsa-miR-4659a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72399
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78829
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97339
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPATA33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65692
hsa-miR-127-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
MOLT13	CCLE Cell Line Gene Expression Profiles	1.0	1.4422
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03302
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
SHISA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07408
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58009
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.66578
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46454
Perturb_7838_KO_AGO1_SRP136692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.4109
hsa-miR-548b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IGSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5545
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57647
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12005
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41383
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18187
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2158
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826897
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18307
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29182
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10527
Response to antipsychotic therapy (extrapyramidal side effects)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.908
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85799
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832055
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Unnamed_2_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849119
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961227
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	1.42278
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
Mean Blood Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
Diastolic Blood Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
HGH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09484
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7153-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20837
SPDEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5961
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.168324
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98719
SLR21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93533
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73155
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3202
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51252
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23608
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902048
H2818	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26811
hsa-miR-3924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
hsa-miR-587	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW756	DepMap CRISPR Gene Dependency	1.0	2.1216
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02307
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918461
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856208
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3703
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
hsa-miR-4731-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
hsa-miR-3673	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38689
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81439
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QM-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.964801
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	4.41877
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892733
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-670	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1187	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41653
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
oral cleft	GWASdb SNP-Phenotype Associations	1.0	0.583787
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28221
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1271	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3205
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79321
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Lung adenocarcinoma_LUAD_TCGA-44-2657-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144	CCLE Cell Line Gene CNV Profiles	1.0	1.42813
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64663
hsa-miR-548i	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48006
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myocardial infarction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45842
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11188
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
short tibia	MGI Mouse Phenotype Associations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
HMCB	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12746
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96659
Skin-t cell	Tabula Sapiens Gene-Cell Associations	1.0	0.113578
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03517
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24791
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.35165
gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.894262
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.0837
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00083
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18313
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826805
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10232
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27579
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5952
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain_CT2_DLIT 149	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129244_0_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78688
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96823
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95975
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46659
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80658
hsa-miR-4257	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37162
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.22565
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932428
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06055
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
hsa-miR-218	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34778
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Perturb_16897_KI_Htt_SRP250656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82358
PWWP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62611
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974033
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02227
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942579
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16258
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.136762
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25179
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.052068
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC18B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78651
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13247
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4235
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971177
Skin-nkt cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0514092
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4719
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3130-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548ab	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.44852
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78656
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94179
hsa-miR-337-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8875
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4786-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10379
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31332
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Mammary-t cell	Tabula Sapiens Gene-Cell Associations	1.0	4.57142
TMEM89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94709
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Systolic blood pressure (cigarette smoking interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.15229
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3U6-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881128
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74726
hsa-miR-548h	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.894262
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	3.42719
hsa-miR-3132	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2605
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OSBPL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00918
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.86053
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11931
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Blond vs. brown/black hair color	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.23979
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31526
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0391
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850029
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3546
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30406
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medication use (agents acting on the renin-angiotensin system)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.73979
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29427
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89085
SNU-C4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05365
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946552
MIDEAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3666
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38184
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.200322
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
D-283MED	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03758
hsa-miR-3188	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47486
Perturb_13051_KD_Gad2_SRP304099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.8686
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUDHL5	CCLE Cell Line Gene Expression Profiles	1.0	1.57862
KIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91861
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70651
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
SNU308	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77477
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67374
Perturb_15031_Mut_Csf33_SRP347624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
Cholangitis, Sclerosing	DisGeNET Gene-Disease Associations	1.0	null
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1457
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87599
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09765
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14601
Stroke	dbGAP Gene-Trait Associations	1.0	0.022251
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839401
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.149881
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35631
PMC12464728-HSR2-8-e71283-s008.pdf-350-SP110_SP110	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.472104
HT115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65641
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-a-Classification_of_camel_SON_basal_genes_-_transcription_factors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	2.45415
mRNA cleavage stimulating factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
PMC9240038-41467_2022_31337_MOESM5_ESM.xlsx-Sheet1-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10082
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.071162
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL3-CLOSEST_GENE_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
TRIM33_KD_GDS4071_449_human_HMEC-TR mammary epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
U-87-MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
CAMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57927
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93538
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.090595
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36436
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4728
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925465
hsa-miR-548o	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mp9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.52876
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11923
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935525
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90822
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82534
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36282
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42515
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.28236
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94015
Perturb_17328_KO_Dis3_SRP278122	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.36181
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2419
NCI-H1304	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01015
LEDGF_KD_GDS1580_249_human_293T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48831
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55882
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
THAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7665
Zinc finger, C2H2-like	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64538
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15852
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15375
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-502-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49903
Lymph_Node-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	1.93161
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65522
RXR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0737
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03152
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62649
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-C5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08307
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
Diastolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.65229
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90368
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03008
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE94849_6_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6601
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81583
vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11034
PLA2G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13283
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-514b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-3.39254
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.24408
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93528
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54516
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26004
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.99018
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.41357
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-888	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	2.28914
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.858194
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17355
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19971
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964468
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26963
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC11264515-40246_2024_644_MOESM2_ESM.pdf-16-ZFHX3_ZFHX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21249
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3387
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89102
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.45562
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922932
HS695T	DepMap CRISPR Gene Dependency	1.0	2.59557
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16783
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.35103
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.054236
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09967
HEC1A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93761
ZNF217	ChEA Transcription Factor Targets	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.930035
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
EFM-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03412
COV318	CCLE Cell Line Gene CNV Profiles	1.0	2.18506
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
hsa-miR-485-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
SNU61	CCLE Cell Line Gene CNV Profiles	1.0	1.79048
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27911
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
Diastolic blood pressure	GWAS Catalog SNP-Phenotype Associations	1.0	1.12786
GSE114992,GSE114993_0_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.21693
Sarcoma_SARC_TCGA-UE-A6QT-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47933
PABPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91396
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907976
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28028
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3869
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24025
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15002
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1597
BAG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23826
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21493
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17373
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870497
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6971-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69081
HS766T	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831619
hsa-miR-516a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.13509
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24088
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70784
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986628
Perturb_5523_KD_Apoa4_SRP393880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22168
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
hsa-miR-514	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
HCC1954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20662
Lung adenocarcinoma_LUAD_TCGA-38-7271-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.070239
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0107
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26183
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33278
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4255	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ZBTB22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84917
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
CHL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1554
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF705B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89438
Lymph node	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.94879
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53959
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15661
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73813
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ATOH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56848
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
pancreatic neoplasms	GAD Gene-Disease Associations	1.0	null
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64905
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36147
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93393
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pulse pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932488
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1089
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83447
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Perturb_6380_KO_Snf5_SRP271283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.3655
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11460_KO_Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.26597
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77317
KYSE140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50128
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19387
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60371
GSE143643,GSE143644_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
DNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93831
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75013
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998785
hsa-miR-1276	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
hsa-miR-548y	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
CREBRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96022
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28745
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94687
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7706
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905512
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09469
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-8	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22835
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47841
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
MFSD6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05867
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4263	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15106
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871676
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
COQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76364
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3495
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94054
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
REST	ChEA Transcription Factor Targets	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.06228
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72921
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Periventricular white matter hyperintensities	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24099
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32824
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
HS766T	CCLE Cell Line Gene CNV Profiles	1.0	1.58586
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77742
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08187
UMUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55284
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.301
SOX17	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Perturb_16729_KO_miR301a_SRP131007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.7959
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4408
hsa-miR-4733-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25371
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29846
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886057
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.092076
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27448
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12377
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916957
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86935
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902048
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
response to antipsychotic therapy (extrapyramidal side effects)	GAD Gene-Disease Associations	1.0	null
GSE137914_0_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89867
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843563
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.14799
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75173
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11233972-mmc1.pdf-3-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4468	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907822
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
schizophrenia	GWASdb SNP-Disease Associations	1.0	1.00407
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8423
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.603
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
physical disorder	GWASdb SNP-Disease Associations	1.0	0.372658
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.952302
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82517
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43531
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6349
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94664
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945958
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42068
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4673	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2444	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
SW1990	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SW1417	CCLE Cell Line Gene CNV Profiles	1.0	1.34562
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983589
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47219
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
F11R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00492
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27105
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29576
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
psychosis	GWASdb SNP-Phenotype Associations	1.0	0.882984
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.79696
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860748
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.03979
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83061
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alcohol Consumption	DisGeNET Gene-Phenotype Associations	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1178
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52641
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
CHAGO-K-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19715
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0086
Perturb_7769_KD_Y14_DRP003223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.8544
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT55	CCLE Cell Line Gene CNV Profiles	1.0	2.82018
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6448
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1117
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Perturb_16663_KO_Zfp36/Zfp36l1_SRP273454	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.98956
MEC1	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
B-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77265
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00025
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
NCI-H128	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73017
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4777-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87667
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957396
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89795
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15793
Lymph_Node-type i nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	2.9374
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69152
Platelet Component Distribution Width Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28463
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.263226
SPTLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70369
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38567
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14878
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41478
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6993
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79056
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mean arterial pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61949
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47119
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930442
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999482
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13469
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
Diastolic Blood Pressure Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29177
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.755
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.894262
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58987
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03841
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.081408
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849119
NatC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-GATA3_mod_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01127
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879316
D-423MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-6851-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1641
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.6045
Perturb_1310_KO_Cntnap4_SRP387040	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.89228
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
hsa-miR-425	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF735	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03014
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18161
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
MEC2	CCLE Cell Line Gene Expression Profiles	1.0	1.72199
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.438
NCIH446	DepMap CRISPR Gene Dependency	1.0	6.56061
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1592
rituximab_homo sapiens_gpl570_gds3829	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5528
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PLXNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41489
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81065
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848336
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37961
FZD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52973
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.48834
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25699
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69522
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71292
hsa-miR-449a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50781
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23626
hsa-miR-3929	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84617
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907035
Lung adenocarcinoma_LUAD_TCGA-44-A47G-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83995
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2030	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854499
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20525
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847831
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.152551
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
Rectum adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JHUEM2	CCLE Cell Line Gene Expression Profiles	1.0	2.45905
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14691
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9791
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71673
PMC12323057-13148_2025_1945_MOESM2_ESM.xlsx-17-Supplementary_Table_17_Overview_of_number_of_targets_genes_shared_with_THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
HDAC6	ENCODE Transcription Factor Targets	1.0	null
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84771
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11252
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-NFATC3_mod_NFATC3	Rummagene Transcription Factor Associations 2026	1.0	null
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1215
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41114
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99777
Melanoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.59901
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8261
hsa-miR-3614-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.908
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC10898050-12967_2024_4947_MOESM2_ESM.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_between_the_TCF7_CD8_memory_T_cells_and_the_other_memory_CD8_T_cells_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4161
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6784
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29922
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67726
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
endocrine gland cancer	GWASdb SNP-Disease Associations	1.0	0.367172
HCC-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NMB	DepMap CRISPR Gene Dependency	1.0	3.03555
Hypertension	GWAS Catalog SNP-Phenotype Associations	1.0	0.786836
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Neutrophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.0699
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34648
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00919
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849426
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2878
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39232
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03454
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32458
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4642	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59387
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31594
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Medication use (diuretics)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.423
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4468	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25691
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.62883
hsa-miR-3611	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51304
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00628
hsa-miR-33b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SNU61	DepMap CRISPR Gene Dependency	1.0	2.39898
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.89122
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838004
hsa-miR-548ak	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22328
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7394
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19443
Oil secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842007
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17793
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.544067
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862127
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9724253-12920_2022_1407_MOESM1_ESM.pdf-229-ZNF180_ZNF180	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.04476
A673	DepMap CRISPR Gene Dependency	1.0	3.11991
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-4478	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
GTEX-XYKS-1826-SM-4E3JV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930924
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66285
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_14212_KO_Sp8/Sp8_SRP095936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymph node	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-636	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49171
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.74243
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58469
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68067
Lung adenocarcinoma_LUAD_TCGA-93-7347-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27189
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51182
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.170932
Pericardial fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38474
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
TRERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.673
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86873
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17983
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38748
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88534
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45068
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5573-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	1.97082
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0017
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80395
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19076
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
hsa-miR-421	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I4-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49352
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16424
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938504
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47101
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96207
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13759
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57476
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885124
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-2110	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
Systolic Pressure	DisGeNET Gene-Phenotype Associations	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5792
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26126
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03511
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF75D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74617
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33148
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08504
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06055
hsa-miR-4256	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18113
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44835
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81722
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2509
Attention function in attention deficit hyperactive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43595
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0083
Perturb_7714_OE_IL25_SRP405857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.78495
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1792
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.91549
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1231	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
abnormal coat appearance	MGI Mouse Phenotype Associations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9607
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	1.90395
hsa-miR-4635	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
NCIH1734	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32046
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28077
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9366
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930819
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03143
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76725
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877937
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26734
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
cation binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00416
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAPAN-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ1-PC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tertiary granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
UACC-893	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74478
KG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1611
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902825
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ZNF845	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01404
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.85382
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-330	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22544
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52486
Anaplastic thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
HUWE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06203
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3065-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61916
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51342
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
Lymphocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.95229
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13597
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830782
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3303
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.438
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HT55	DepMap CRISPR Gene Dependency	1.0	21.1455
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24289
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2208
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45168
Perturb_9209_KO_Cic_SRP076421	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57267
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.817
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
Perturb_3482_KO_Mcph1_SRP401970	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53361
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5118
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934697
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
MDAMB468	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36059
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90249
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.982105
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT55	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23705
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-STAT4_mod_STAT4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33157
inflammatory bowel disease	GWASdb SNP-Disease Associations	1.0	1.69467
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-449b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5626
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7841-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15502
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.039389
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847036
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV318	DepMap CRISPR Gene Dependency	1.0	2.0894
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877531
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24414
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PLOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68781
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49873
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
GSE133555_0_v_1_npm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-302f	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4419b	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53993
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6471-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	0.836362
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77809
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65061
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06438
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24435
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09693
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28152
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03238
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-GATA3_mod_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
short tibia	IMPC Knockout Mouse Phenotypes	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39693
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
kidney disease	GWASdb SNP-Disease Associations	1.0	0.848917
GSE140092_2_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831286
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2631
CTCF	ENCODE Transcription Factor Targets	1.0	null
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14646
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08498
CCDC51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60792
KP-1N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
hsa-miR-3124-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC9577795__F4	PFOCR Pathway Figure Associations 2024	1.0	null
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-559	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
Perturb_7933_KD_Spt6_SRP132004	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.1577
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23931
HCaRG_OE_GDS1411_72_human_HEK293 embryonal kidney cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-135a	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995293
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93881
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
NFATC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10041
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16214
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97658
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6727
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88719
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
Lymph_Node-t cell	Tabula Sapiens Gene-Cell Associations	1.0	2.728
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63982
Perturb_2032_KO_Cnot3_SRP051497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.32706
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51487
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857543
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-580-ZNF799_ZNF799	Rummagene Transcription Factor Associations 2026	1.0	null
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52203
Perturb_17326_KO_Dis3_SRP328540	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.61992
CALU-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Blood pressure	GWAS Catalog SNP-Phenotype Associations	1.0	0.696558
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.24408
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88365
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
EVSA-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.30944
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75208
GSE160817_5_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15743
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2156
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5679
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Lymphocyte Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3125	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair Color	DisGeNET Gene-Phenotype Associations	1.0	null
TP63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75945
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE211744_2_v_0_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.16903
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10350897-j_biol-2022-0528-S1.pdf-194-ZNF804B_ZNF804B	Rummagene Transcription Factor Associations 2026	1.0	null
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
hsa-miR-212	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86407
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6C_mageckTFkoscreen_wo_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09394
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26999
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3607
Perturb_7934_KO_TRESLIN_SRP388894	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.355
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mean arterial pressure x alcohol consumption interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.43979
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979589
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27381
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.859157
hsa-miR-1272	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.827
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27857
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
TP53	ChEA Transcription Factor Targets	1.0	null
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32217
PMC10127334-12920_2023_1521_MOESM2_ESM.docx-0-FOSB_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
ANP32D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11712
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137914_2_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887585
FOXE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18518
CRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53797
myopia	GAD Gene-Disease Associations	1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14014
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3121-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73815
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4279	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924427
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.103245
hsa-miR-4505	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations	1.0	0.713153
abnormal skin coloration	IMPC Knockout Mouse Phenotypes	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38236
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2198
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27812
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02885
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	1.41379
DAOY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26018
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12441
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34029
NDUFS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66306
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32812
GSE227137,GSE227139_2_v_3_themis2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.33908
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47552
Mel501 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38229
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92262
Lung adenocarcinoma_LUAD_TCGA-L9-A444-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73286
MOLT16	CCLE Cell Line Gene Expression Profiles	1.0	1.47403
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
hsa-miR-3685	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
hsa-miR-142-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8638
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828696
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	2.26545
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4330-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4168
ABL1_druginhibition_77_GSE24493	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.43606
hsa-miR-34c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.912084
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.32603
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3145-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31226
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4346-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.148966
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09484
NB1643	DepMap CRISPR Gene Dependency	1.0	2.67366
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87155
GGCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32591
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8048
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
appendix	HPA Tissue Gene Expression Profiles	1.0	0.889255
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70863
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	3.46028
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32269
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885272
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A627-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
GTEX-WOFL-0626-SM-3MJG3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876439
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933532
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.50375
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10718
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38742
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08946
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35223
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119345_2_v_4_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4778-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91859
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.286897
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2935	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67649
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-338-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12395
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30677
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89016
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7837_KO_AGO1_SRP136692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.9815
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854024
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19123
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48871
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54701
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8696
hsa-miR-4686	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.046996
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850029
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
COLO775	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42463
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83307
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.35418
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.10939
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3513_KD_RNPS1_ERP107441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.78417
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78681
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21403
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21551
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EB2	CCLE Cell Line Gene Expression Profiles	1.0	1.66631
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23395
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16985
Perturb_11459_KO_Ezh2/Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.31062
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4708-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
Diastolic blood pressure x alcohol consumption interaction (2df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.5699
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98905
YH-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.63979
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.70042
BAZ2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
SOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
hsa-miR-4714-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
PROKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11978
Perturb_12993_KO_Il1rl1_SRP274117	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.6591
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53942
hsa-miR-548w	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09484
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26208
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989941
HCC2279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79542
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
Hypertension	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.42218
ZNF709	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50795
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894903
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.827209
NCI-H596	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980783
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1611
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67507
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36402
PMC12130184-12276_2025_1441_MOESM5_ESM.pdf-8-ZNF688_ZNF688	Rummagene Transcription Factor Associations 2026	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3874
Perturb_16303_KO_Esr1_SRP115139	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96692
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6157
TE1	DepMap CRISPR Gene Dependency	1.0	2.57074
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89248
ZFP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34638
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11897
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
LU99	DepMap CRISPR Gene Dependency	1.0	3.4538
PMC12021535-CPH4-15-e70011-s001.xlsx-S9-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34951
TTC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89846
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71257
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23855
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856192
abnormality of the face	GWASdb SNP-Phenotype Associations	1.0	0.110636
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13326
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894229
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57858
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4686
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22623
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15422
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43649
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.113025
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.476
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895596
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.246
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31623
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-362-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
premature ovarian failure	GWASdb SNP-Disease Associations	1.0	0.626876
GSE173873_1_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26038
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-11A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26354
orofacial cleft	GWASdb SNP-Disease Associations	1.0	0.681401