association	dataset	threshold value	standardized value
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr9_68309855_A_G_b38	GTEx eQTL 2025	1.0	1.05265
MOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30584
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09445
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04365
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6807
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Transcription factor TFIIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16552
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70428
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93638
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7344
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03353
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15018
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8462
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16122
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5721
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-645-ENSG00000274349_ZNF658	Rummagene Transcription Factor Associations 2026	1.0	null
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23624
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26197
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15378
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0446
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0227
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27995
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37355
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3146
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65346
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5678
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54522
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04257
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13389
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29038
TRAPPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11119
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44663
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16601
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6946
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37601
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28325
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32802
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2186
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95327
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3349
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8527
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133516_5_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09154
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Colo-320 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41483
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	11.4429
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46129
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22333
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03391
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1908
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40623
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5948
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31842
KRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19883
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60827
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF891	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05296
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03829
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239651_1_v_0_ispinesib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44454
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86966
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15877
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32182
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01911
mRNA cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.45141
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38307
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12313
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-196-ZNF658_ZNF658	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.82371
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16585
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34865
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0479
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46839
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51285
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15907
FBXW8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22074
Transcription factor TFIIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0252
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74168
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3661
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01297
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1582
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64037
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07677
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71622
GSE147626_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44903
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.07631
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13529
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03039
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7655
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11107
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08577
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93448
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9464
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07708
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.391
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84679
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15967
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73829
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53932
GSE122509,GSE122513_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07961
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.592
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7349
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31905
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05385
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41347
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15369
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3155
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6825
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11325
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3788
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3161
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48836
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16237
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71354
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4741
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27729
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09583
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4828
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3737
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08687
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55726
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.752
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14076
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01116
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mural cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
Colon descendens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
nucleus	GO Cellular Component Annotations 2025	1.0	null
GOLGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12307
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28951
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96502
MTSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98305
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05903
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64294
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59091
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71949
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3456
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1766
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58188
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3141
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14643
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13291
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3657
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4626
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7536
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3817
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17338
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17761
NCI-H1299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.438
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64776
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08338
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9452
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00291
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58101
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69462
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4828
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7578
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3114
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08554
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SYNJ2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35357
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28846
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7913
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7597
iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12349
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09122
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14327
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41636
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35984
PPME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14984
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29038
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NENF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67175
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17301
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03992
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06719
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44362
GSE76425_0_v_3_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60602
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13743
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9471
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32396
H-1299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.416
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11077
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
USPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86245
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135350_3_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85195
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7679
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11831
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00004
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.193
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01445
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MMADHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05834
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00506
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02424
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32858
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16432
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14079
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.741
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36705
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81894
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.40895
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43562
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6787
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6585
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72606
SW-48 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
ERH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00485
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01514
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03745
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.537
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26244
SEC22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20374
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7767
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0805
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29592
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5859
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29635
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63909
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null