association	dataset	threshold value	standardized value
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30177
hsa-miR-596	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89822
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38345
hsa-miR-1254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.324
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09671
Thymic Carcinoma_Thymus_GSE2501	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.54896
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GI1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.4206
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15846
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-22	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887552
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13019
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4732-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2082_KD_Pan3_SRP087494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
496100603_PCx_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6149
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19502
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6887
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931917
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8979_KD_MEOX2_SRP358321	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.859
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sitaxsentan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966164
lysosome	LOCATE Curated Protein Localization Annotations	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-448	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833716
NCIH1568	CCLE Cell Line Gene Expression Profiles	1.0	1.69667
Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.47074
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00485
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.725
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70532
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-1526-SM-4AT5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21497
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.149324
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.42168
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4773	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07126
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91819
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18802
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.334
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.81036
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857639
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.854469
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184632
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30002
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.943505
ETS1	ENCODE Transcription Factor Targets	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transmission	GeneRIF Biological Term Annotations	1.0	null
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36284
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62313
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33803
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55894
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6199_KO_Elp3_SRP065804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.65748
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC3930188-813067.f1.pdf-161-ZNF653_ZNF653	Rummagene Transcription Factor Associations 2026	1.0	null
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2802
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PBX1	ChEA Transcription Factor Targets	1.0	null
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224004,GSE224005_0_v_6_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45788
hsa-miR-770-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.56192
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6571
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07171
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09305
A-CA-04-2009(H1N1)_18Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79003
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_5_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-0326-SM-4B66V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876557
MCF7_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013407
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-1226-SM-4AD6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862214
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1318
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_Myeloid-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880838
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	197.08
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28648
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871406
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5111
OVKATE	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.19282
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01249
HCC2218_BREAST	CCLE Cell Line Proteomics	1.0	3.04943
presynaptic membrane	GO Cellular Component Annotations 2015	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31319
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53452
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80088
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.3331
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01689
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72335
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15404
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31327
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4529-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05604
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0068
JHOM2B	CCLE Cell Line Gene Expression Profiles	1.0	1.69855
SB-29-ZH97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203443
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925478
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-SKIL_mod_SKIL	Rummagene Transcription Factor Associations 2026	1.0	null
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00926
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.70952
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864946
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917317
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09812
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04059
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832868
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27614
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929855
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47142
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40367
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN008_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0264
MKN45	DepMap CRISPR Gene Dependency	1.0	6.09402
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Flp-In-T-REx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03165
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_768_mouse_Skin - 7 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37486
Perturb_6453_KD_YAP1_SRP056665	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967888
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.35676
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95284
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64343
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.58828
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68676
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1158
TCF4	ChEA Transcription Factor Targets	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01565
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57147
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alveolar lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60588
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	2.42446
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16509
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13894
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01126
240min_BMP4 vs ctrl_hESC (Human) [19664995]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10265
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49841
MELHO	DepMap CRISPR Gene Dependency	1.0	2.13857
Fatty Liver	CTD Gene-Disease Associations	1.0	1.46621
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24731
MCF7_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140177
MCF7_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172882
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877705
PMC3091648-1471-2164-11-451-S5.DOC-0-Top_100_CEBP_Candidate_Targets_Unknown_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29187
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19484
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69068
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52712
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13655
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.901056
PMC10350897-j_biol-2022-0528-S1.pdf-194-ZNF804B_ZNF804B	Rummagene Transcription Factor Associations 2026	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A549_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138208
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00896052
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-157-NFE2L3_NFE2L3	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91356
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07678
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.526
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60011
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33721
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934447
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882632
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95455
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77041
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.18424
KAT2A	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2824
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874508
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1871
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
identification	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10246
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889643
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44717
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3485261-pone.0046600.s008.docx-0-V_SMAD4_Q6_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5989
TAF1	ENCODE Transcription Factor Targets	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8188
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57774
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16255
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00863
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.708
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS6KA3_knockout_73_GSE22137	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.8967
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27861
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61626
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844508
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03569
Lung adenocarcinoma_LUAD_TCGA-44-2659-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
UBE2E1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.944796
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1A2	Pathway Commons Protein-Protein Interactions	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30814
Orbital area, ventrolateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00618
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.493
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE158197_2_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100595_PCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23094
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01427
PMC3076323-pone.0018064.s016.xls-MYCN_targets_Marson_GSE6007-Unnamed_1_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849881
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92472
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917095
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.32346
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971747
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11436
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63406
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Papillary Thyroid Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3249
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35421
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4764-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
physiological	GeneRIF Biological Term Annotations	1.0	null
pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195377
hsa-miR-1299	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79232
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890141
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4642	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.49071
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.24525
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38703
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75501
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894253
Daidzin_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0239826
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68676
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12248
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11771
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54245
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21914
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.29225
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ligase activity	GO Molecular Function Annotations 2015	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Tozasertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112533
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0945
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924924
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
K562_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159898
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5712
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27713
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01018
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949758
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Fasudil_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172403
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960246
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29664
PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11309
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
membrane	GO Cellular Component Annotations 2015	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8934
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.873014
SKBR3	CCLE Cell Line Gene Expression Profiles	1.0	1.47317
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055767
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05516
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16271
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22992
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.485575
Gastric adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	2.33816
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.389296
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2329
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34588
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71217
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39714
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8728_KD_ZNF414_SRP269946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
KLF4	ChEA Transcription Factor Targets	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.561
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59839
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25
A549_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014295
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4799-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4293
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0144
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00535
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01957
Perturb_122_KD_Ywhaz_SRP045772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.633
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35651
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ligase	GeneRIF Biological Term Annotations	1.0	null
Rifaximin_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0124526
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94908
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920522
HS895T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59835
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85435
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6459557-pbio.3000201.s012.xlsx-Sheet1-FOXD1_FOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4654	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
diethylstilbestrol_mus musculus_gpl81_gse1839	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8417
Perturb_14319_KD_YAP_SRP251526	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.63835
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Fluorouracil_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122991
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.2991
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13576
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5637904-PATH-243-193-s015.xlsx-human_up_in_ductal_SOX11-Table_S4A_Upregulated_genes_in_lesions_and_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_the_mammary_duct_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04305
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0114685
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31401
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90773
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.898695
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11351
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22388
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921488
MCF7_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00937174
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.96206
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25923
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11524
MCF7_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176979
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CAL51	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07237
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14765
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9807
Inflammation	CTD Gene-Disease Associations	1.0	1.25588
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04602
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03079
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
endosome membrane	GO Cellular Component Annotations 2015	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10878
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KKU100	DepMap CRISPR Gene Dependency	1.0	2.23072
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57964
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42041
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ES8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.68063
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06022
GSE210580_5_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1105
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836488
Perturb_15034_KD_WDR5_SRP024294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.25695
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28694
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Keratosis follicularis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.523845
their	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17062
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7783
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2485
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	3.60616
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61926
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925478
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07096
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31521
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235268
MCF7_Hesperadin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184177
MCF7_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171976
RARG-19884340-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91994
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145509
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21781
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57697
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
hsa-miR-100	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24366
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892689
Cadmium levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828429
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829293
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00416
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26988
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965329
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLD1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13686
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995397
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03212
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67028
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22637
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880682
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11263707-41419_2024_6896_MOESM6_ESM.pdf-78-ZNF329_ZNF329	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3R1-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	1.0	1.41628
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-146a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15326
SNU478	DepMap CRISPR Gene Dependency	1.0	7.77181
K562_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185395
STAT1	ENCODE Transcription Factor Targets	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92179
hsa-miR-4699-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Carmofur_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110044
ZNF143	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79041
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1303	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
IM95	CCLE Cell Line Gene Expression Profiles	1.0	2.07318
Turner Syndrome_CNS - Brain (MMHCC)_GSE1606	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.93365
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14952
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903192
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62874
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46589
PANC0327	Achilles Cell Line Gene Essentiality Profiles	1.0	1.69211
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23667
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuronal	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86292
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0451
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13353
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
nakatpase	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35142
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114690_1_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
DCP1A	ChEA Transcription Factor Targets	1.0	null
GSE126127_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KG-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3	ChEA Transcription Factor Targets	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59557
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4764
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97024
ACSM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51077
vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHD1-19587682-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102187_0_v_1_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Simotinib_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0252992
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.00382
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.589234
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829635
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61695
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139239_3_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.05015
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SF-1926-SM-4AT5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0972
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_NANOG_targets_Boyer_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4013
RWPE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08129
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8632
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10153265-media-3.xlsx-BENPORATH_NANOG_TARGETS_v2023_1-STANDARD_NAME_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84522
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59976
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21695
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16737_KO_Rag2/Il2rg/Notch3_SRP220745	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.12856
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.513204
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126402_2_v_0_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17886
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38458
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Patupilone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0116807
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99277
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7643
MITF	ChEA Transcription Factor Targets	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41506
MCF7_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114216
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627485
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24901
RPP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rimonabant_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0205646
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159732
Ebolavirus(ZEBOV)_5day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92291
CHLA90	DepMap CRISPR Gene Dependency	1.0	3.31817
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12696
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
HuH-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
t-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30714
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994973
YMB-1-E	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.39533
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1519
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cinacalcet_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0389605
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06813
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1466
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2345
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BACH1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4707_KD_Dnmt3a_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9071
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.19704
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20868
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein K48-linked ubiquitination	GO Biological Process Annotations 2025	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966101
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13795
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04086
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.172
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.282909
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40086
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4520b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42244
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.824112
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6375
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31117
MCF7_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146197
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.52063
hsa-miR-105	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881869
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861177
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tuned	GeneRIF Biological Term Annotations	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41057
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18278
MCF7_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222448
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052512
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046143
K562_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180548
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0709
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987525
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91051
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27101
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979146
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	2.4656
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31509
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23058
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6038
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37134
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.88446
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
G401	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66697
Pentoxifylline_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0139169
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7038
hsa-miR-2276	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Binimetinib_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.035969
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07584
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995413
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08558
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.999878
HCC70	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.17063
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21524
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02096
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23269
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835885
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04082
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03572
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35672
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1056
A549_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114233
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968165
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51186
UBB_KO_GDS3906_496_mouse_Testis -  28 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0121
ubiquitin-like protein transferase activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17171
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU398	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75364
GSE200352_9_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.55445
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11114
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2453
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934099
NTRK2_drugactivation_66_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.00166
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6471-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bestatin_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0143674
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45594
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCF7_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125396
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897733
DAN-G	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.92429
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_28_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11114
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03971
MCF7_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146171
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Papillary thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06149
CRCGN012_HEPG2_24H:B16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18791
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829183
postcentral gyrus, left, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.897043
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06577
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skbr3	HPA Cell Line Gene Expression Profiles	1.0	1.1829
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10809
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mulibrey nanism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
5-Hydroxyflavone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIBR189	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
CLOCK-20551151-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01413
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44674
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232375
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2015	1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170519
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66283
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-0826-SM-4AD5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3379
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19885
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958192
IKBKB_knockdown_86_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56195
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21165
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49029
L33	DepMap CRISPR Gene Dependency	1.0	2.12071
Perturb_11704_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.86479
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.446
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91604
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02869
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04507
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2811
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-SKIL_mod_SKIL	Rummagene Transcription Factor Associations 2026	1.0	null
HAUS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.50006
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295371
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_31_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56387
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.38412
HCC4006	CCLE Cell Line Gene Expression Profiles	1.0	1.67361
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
20min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825951
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049572
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16734
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971207
HCC70	DepMap CRISPR Gene Dependency	1.0	2.96523
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
647V	DepMap CRISPR Gene Dependency	1.0	3.58146
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11212
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908286
LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDA-MB-231	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.40291
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS834T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51401
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76664
DNAPK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Perturb_17244_KO_Klf3_SRP029447	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00229
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17308
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1984
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.625711
Sunitinib_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0269257
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MCF7_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.011791
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.91204
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36433
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08352
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903698
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79999
ethinyl estradiol_oryzias latipes_gpl16266_gse44859	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE200159_1_v_0_setd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_1_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UBB_KO_GDS3906_492_mouse_Testis -  14 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16461
icSARS CoV_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77271
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73859
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0756
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.5461
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68472
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Filgotinib_KATO III	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0345629
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAK1_druginhibition_166_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52557
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1428	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.34555
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58563
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23906
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2565
crizotinib_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0192818
SMARCA4	ChEA Transcription Factor Targets	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02458
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178019
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08479
MCF7_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0105431
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	2.45953
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7903
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24732
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.59308
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02089
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221112
establishment	GeneRIF Biological Term Annotations	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein ubiquitination	GO Biological Process Annotations 2015	1.0	null
NCI-H2066	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44807
PAPA syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014341
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GJ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56494
hsa-miR-4720-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
postcentral gyrus, left, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831076
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889477
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9687
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.504724
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.856
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03745
MCF7_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136658
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23218
NRF1	ENCODE Transcription Factor Targets	1.0	null
SUM52PE	DepMap CRISPR Gene Dependency	1.0	8.69664
Perturb_15044_KD_PTBP1_SRP124244	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.8654
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIG3TD	CCLE Cell Line Gene Expression Profiles	-1.0	-2.83266
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925431
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74938
SNU620	DepMap CRISPR Gene Dependency	1.0	2.70794
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.62688
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28649
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.911111
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41832
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27713
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16617
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear origin of replication recognition complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
an3ca	HPA Cell Line Gene Expression Profiles	-1.0	-1.2333
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6313
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11277
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895388
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.851364
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2201
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47828
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18777
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050795
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069973
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5031867-mmc2.xlsx-RYTTCCTG_V_ETS2_B-GENE_SYMBOL_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79236
T-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_2-Methoxyestradiol_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123754
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4805
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ERBB2_knockdown_235_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78579
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8223
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960569
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47362
MCF7_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138541
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.970228
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0849
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24585
hsa-miR-3944-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.0961
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
X31(H3N2)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80875
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951123
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52661
hsa-miR-549	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
A549_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134032
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7223
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99604
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27871
17009876-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_spleen-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05917
CRCGN015_MCF10A_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13665
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48379
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.53198
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9846
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F2	ChEA Transcription Factor Targets	1.0	null
CAL-33	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.9822
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11534
proteasomal protein catabolic process	GO Biological Process Annotations 2023	1.0	null
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07963
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33937
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37379
MCF7_Lomustine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128582
Perturb_17525_KO_Foxp3_SRP366054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.24111
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
A549_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014407
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.86058
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.47083
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901049
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Simotinib_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0188561
vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41416
A549_TGX-221_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173282
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-525-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
JTE 013	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22729
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43845
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54033
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13438
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152379_0_v_4_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_5_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13927
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36594
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.989838
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00925
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06581
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28531
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.90069
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.12412
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456641
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.931968
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63583
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08554
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.21919
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1061_KO_Esr1_SRP087718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.89332
Perturb_1810_KO_lncFAO_SRP192861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.92044
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.75903
MCF7_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120879
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11924
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4392_KD_RNF5_SRP276909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.22794
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.879847
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962521
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345241
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.51302
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3062
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861167
RFX5	ENCODE Transcription Factor Targets	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22055
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53198
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906171
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894237
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846421
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961695
UBE2D1	Pathway Commons Protein-Protein Interactions	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3942-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29054
WM793	CCLE Cell Line Gene CNV Profiles	1.0	1.50831
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.5686
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56551
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268176
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.96109
Phosphoric acid	HMDB Metabolites of Enzymes	1.0	null
Pentagastrin_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0185681
Tetracycline (hydrochloride)_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0121699
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nanog_16518401_mesc_lof_mouse_gpl1261_gds1824	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.036465
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4836
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNRF1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12399
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967115
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5117
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944157
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3812
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912357
CRCGN008_HEPG2_24H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1005
SKES1_BONE	CCLE Cell Line Proteomics	1.0	2.03045
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.98819
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5348
496100585_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12622
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21808
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-47-ZNF197_ZNF197	Rummagene Transcription Factor Associations 2026	1.0	null
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263281
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861956
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI8226	DepMap CRISPR Gene Dependency	1.0	2.00514
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97466
hsa-miR-938	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hf19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995413
SARS-BatSRBD_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47825
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.662611
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02637
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49671
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RD-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MCF7_ZM 447439_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160609
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834765
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39985
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4742-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486014
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25678
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24194
Perturb_4415_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
E2F4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837117
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.784
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09401
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882917
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.506954
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76619
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29289
znrf2	GeneRIF Biological Term Annotations	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Idarubicin (hydrochloride)_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.037963
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37723
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.501435
TAL1	ENCODE Transcription Factor Targets	1.0	null
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41734
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16126
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0616
RHJT	DepMap CRISPR Gene Dependency	1.0	2.3415
vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal dominant intellectual developmental disorder 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18416
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979063
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE191138_2_v_4_fmo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12329_KD_SRSF1_SRP196880	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.67233
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.28591
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129872
CRCGN014_HEPG2_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14947
PC-3_[JPC-3]	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.90348
COV644	CCLE Cell Line Gene Expression Profiles	1.0	1.53003
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.848
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36801
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998142
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48019
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43096
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OELE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46079
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6567
Acenaphthoquinone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14568
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02869
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.884244
1min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0101799
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
vacuolar membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945516
ubiquitin	GeneRIF Biological Term Annotations	1.0	null
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34332
players	GeneRIF Biological Term Annotations	1.0	null
HCC366	DepMap CRISPR Gene Dependency	1.0	8.07978
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Perturb_14412_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71978
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3024
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878861
HS618T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82748
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
znrf1	GeneRIF Biological Term Annotations	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GP2D	Achilles Cell Line Gene Essentiality Profiles	1.0	2.5871
Norwalk Virus_HG23_19515767_GSE15520	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.29129
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10350077-media-8.xlsx-Controls_LPS_enriched_Down_KEGG-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03319
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65871
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5972
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849807
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43393
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.21515
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03571
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353408
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90621
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.897125
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19521
PMC6977700-aging-12-102667-s004..xlsx-Stage1-The_identified_3126_dysregulated_LmiRM-CTs_in_stage_1_of_MI_1_day_of_MI_using_our_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52888
Adenosine monophosphate	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4291	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36778
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.11326
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887683
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-59-ZNF101_ZNF101	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.492
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.854469
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18192
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88883
BT483	CCLE Cell Line Gene Expression Profiles	1.0	1.96461
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07126
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MCF7_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0247881
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52346
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DMS273	CCLE Cell Line Gene CNV Profiles	1.0	2.00884
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_121_KD_Ywhaz_SRP045772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.4841
DM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71961
protein modification by small protein conjugation or removal	GO Biological Process Annotations 2015	1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942085
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52782
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
CRCGN013_HEPG2_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02843
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09037
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932737
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17349
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.07376
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62839
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3321
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840231
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97465
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07873
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
postcentral gyrus, left, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04921
hsa-miR-103a-3p	MiRTarBase microRNA Targets	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11903
Erlotinib_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00819662
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903812
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.004
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208693
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46066
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17402
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H720	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0968
Brain Lower Grade Glioma_LGG_TCGA-HT-7601-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28645
Perturb_10391_KD_BRDT_SRP273737	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37415
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052259
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.376202
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75566
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.55918
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16999
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17841
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-625	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TCF12	ENCODE Transcription Factor Targets	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882632
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2074
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E8-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hedgehog signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
ChIP_PHC1_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6327
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043294
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55856
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998899
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37362
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33078
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866719
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0272
hsa-miR-885-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163934
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09503
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1526-SM-3NMCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971423
hsa-miR-3183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97547
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28878
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870549
colon	HPA Tissue Gene Expression Profiles	1.0	1.27507
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1236	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.23806
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CADO-ES1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.35711
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76221
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4144_KO_Bcl11a/Bcl11b_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.5298
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41958
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE5	DepMap CRISPR Gene Dependency	1.0	2.95168
MCF7_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119847
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
10min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02962
Acute Myeloid Leukemia_LAML_TCGA-AB-2815-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.91031
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20189
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88857
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4171_KO_Banf1_SRP302680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876052
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66883
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950483
Lung adenocarcinoma_LUAD_TCGA-38-4632-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046756
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250665
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00758
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4883
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79849
Perturb_11055_KO_Stab1_SRP149099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03093
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12169
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42724
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7837-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4723-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
KMRC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.8851
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.22242
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
K562_AG-14361_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170977
SB-29-ZH97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295812
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0769
Striatum ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07214
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09098
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60965
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-217	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08928
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3091648-1471-2164-11-451-S5.DOC-0-Top_100_CEBP_Candidate_Targets_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4668-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
MCF7_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163874
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04382
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68627
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Lenalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152916
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30038
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05528
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856891
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.80438
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51996
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01019
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adaptive Immune System	Reactome Pathways 2024	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
MCF7_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141976
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54713
GSE231799_3_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924644
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_6_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lenalidomide (hemihydrate)_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0230457
Chlorhexidine (diacetate)_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0841367
basomedial amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25538
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29087
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08729
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS840T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.48227
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59138
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4803	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976107
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13079
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_4_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25261
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14811
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9691391-7945884.f3.pdf-82-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
plasticity	GeneRIF Biological Term Annotations	1.0	null
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pc-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Ellagic acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138599
CRCGN011_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13855
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314501
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.98642
RARG	ChEA Transcription Factor Targets	1.0	null
A549_Luminespib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139041
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2938
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069973
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913721
ubiquitous	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16283
MCF7_WP1066_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168677
KDM5B	ENCODE Transcription Factor Targets	1.0	null
RARG-19884340-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980377
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43148
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17596
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34467
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.11283
Ebolavirus(ZEBOV)_3day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.37895
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20803
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
Perturb_13063_KO_Bak/Bax_SRP055036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
F5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.82865
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.12805
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1756_KO_Ripk3_SRP226420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.90545
Learning Disorders	CTD Gene-Disease Associations	1.0	1.01625
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.81891
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38234
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.56591
MEF2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of autophagosome-lysosome fusion	GO Biological Process Annotations 2025	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-7954	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.92234
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143563
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993892
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35668
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01294
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
K562_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016274
hsa-miR-4769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_NK_cells-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4776
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05137
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.14341
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.4817
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4076-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50318
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40844
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2095
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843574
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18245
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10209342-mmc9.xlsx-UBE2D3_interactors-UBE2D3_interactors_used_for_Venn_Diagrams_from_MINT_STRING_UniProt_IntAct_BioGRID_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.619788
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09568
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942085
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882956
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69862
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ubiquitin protein ligase activity	GO Molecular Function Annotations 2015	1.0	null
GSE239747_2_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92569
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.895
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56867
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17239
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19836
NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QLQW-0426-SM-447A7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947626
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50I-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8299
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38144
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01953
GSE195559_8_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19748
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02056
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20492
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68646
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05492
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.930471
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12606
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50069
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.259
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23842
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-582-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163052,GSE163198_4_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
e21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904485
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58363
Perturb_4236_KD_Cnot7_SRP091584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.40426
vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06978
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.627275
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_941_dysregulated_LmiRM-CTs_in_MI_using_traditional_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12483
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33564
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01642
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L32	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.579
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25716
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918657
TP63	ChEA Transcription Factor Targets	1.0	null
synaptic membrane	GO Cellular Component Annotations 2015	1.0	null
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-936	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04044
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56896
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863455
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.90728
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06543
KU812	DepMap CRISPR Gene Dependency	1.0	2.90599
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983271
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39764
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18665
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7645-01A-22R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54491
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71559
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300942
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96962
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269174
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32947
DMRT1	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05902
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56327
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11012
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8384902-mmc5.xlsx-H889_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-2.00392
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51966
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09483
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28465
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.93081
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00528
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068357
6-Aminochrysene	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
UBE2D3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1269	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1981_KO_Nr1h2/Nr1h3_SRP158140	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.68151
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.65726
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872726
RMC-6236_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0372103
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-380	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
EN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46623
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sepsis_Splenocyte_GSE4479	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.2008
Fumitremorgin C	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
OE33	DepMap CRISPR Gene Dependency	1.0	2.55676
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852481
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_CYC116_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175136
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5525
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Cediranib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125581
PMC11364504-41388_2024_3115_MOESM2_ESM.pdf-164-ZNF629_ZNF629	Rummagene Transcription Factor Associations 2026	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15588
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510599
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855096
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32121
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.6893
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43497
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16455
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85163
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08217
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082519
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79874
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.617954
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU1919_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.8384
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76038
NTRK3_drugactivation_67_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.00166
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01644
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.95168
COR-L279	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.16411
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918375
hsa-miR-3691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
maintenance	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07518
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21424
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15218
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_5_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
UOK101	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22358
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922139
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1321
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21137
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52407
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954386
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922784
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	2.81554
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Pyridoxine_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0204363
demands	GeneRIF Biological Term Annotations	1.0	null
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7473
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.05163
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994824
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46056
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-1245b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12705
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205717
GSE242083,GSE242098_3_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3752
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14175
YWHAQ	Pathway Commons Protein-Protein Interactions	1.0	null
H4	DepMap CRISPR Gene Dependency	1.0	2.28994
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-99a	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
ERG	ChEA Transcription Factor Targets	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832042
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE89018_1_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-44-UR36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246657
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35212
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14586
Farage	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24577
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38544
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27358
many	GeneRIF Biological Term Annotations	1.0	null
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
UBE2D4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13394
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.959454
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7090-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7426
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08775
MCF7_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115693
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25513
A549_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015727
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4069
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24182
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31562
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824199
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cdkn1b_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl6246_gse27672	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.999859
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847448
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89626
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894064
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16005
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK2_defectivemutant_17_GDS1793	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.5092
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81052
PMC2742312-1479-7364-3-3-221-S3.PDF-153-HOXA11_HOXA11	Rummagene Transcription Factor Associations 2026	1.0	null
CAL-148	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.27861
PAX5	ENCODE Transcription Factor Targets	1.0	null
MERO14	DepMap CRISPR Gene Dependency	1.0	3.26778
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70638
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
hsa-miR-646	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
MCF7_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139283
H4	CCLE Cell Line Gene CNV Profiles	1.0	2.31431
MCF7_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126047
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2261
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5333
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851296
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52559
ESR1-22446102-UTERUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1569	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.6702
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3657	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00792
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
dorsolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01957
PMC8045971-Table_3.xlsx-vs_LPS_ctrl-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02919
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61806
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126371
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.35261
HEC1A_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	3.78966
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13658
ELF5	ChEA Transcription Factor Targets	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911259
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993441
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-MLL-AF4_Patient_Cells-Non-spreading_targets_gene_names_302_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60406
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03612
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980428
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100583_PCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.01372
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851175
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
K562_Maraviroc_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220892
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11363
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19483
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97012
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08752
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962628
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10974
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35036
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.884233
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1785
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91819
Prostate adenocarcinoma_PRAD_TCGA-HC-7213-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92214
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15585
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853346
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846564
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1893
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52035
hsa-miR-103a	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51903
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5711
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4318
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89604
Perturb_15017_KI_Stat6_SRP374172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.0332
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-606-ENSG00000050344_NFE2L3	Rummagene Transcription Factor Associations 2026	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1177
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAP2K1_druginhibition_172_GSE39984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.87985
NFE2	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03238
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42609
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01689
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21657
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12987
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58963
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.01625
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05137
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477794
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
vacuolar part	GO Cellular Component Annotations 2015	1.0	null
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39563
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
znrf	GeneRIF Biological Term Annotations	1.0	null
GTEX-U8XE-1826-SM-4E3HV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915726
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3389_KO_Tcf7_SRP217200	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.14829
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1694	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.63624
hsa-miR-498	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
BRCA1	ENCODE Transcription Factor Targets	1.0	null
mp1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.965615
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.17493
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09508
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897597
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54369
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79535
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08749
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055224
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06488
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7229-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
REST	ENCODE Transcription Factor Targets	1.0	null
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30805
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE212074_0_v_1_pus1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397554
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.38387
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endosome	LOCATE Curated Protein Localization Annotations	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein polyubiquitination	GO Biological Process Annotations 2025	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41223
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205645
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895502
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72735
CAOV3	DepMap CRISPR Gene Dependency	1.0	2.63637
Perturb_14655_KD_TCF7L2_SRP050497	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	3.88788
WAY 316606	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66674
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842885
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975894
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45737
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57738
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.086964
MCF7_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132634
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.07989
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831845
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217541,GSE217543_3_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192812
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012699
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1270	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0121
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.20394
15474998-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289394
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1399
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.882702
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02858
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638277
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U251MG	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.65442
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960618
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
CRCGN015_MCF10A.TP53.M_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2398
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35585
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5315
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37774
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75562
HDAC6	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
TE617T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53357
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49767
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831992
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21921
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61421
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0064
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211607
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051039
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205762
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.1409
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.552888
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC59	CCLE Cell Line Gene Expression Profiles	1.0	3.30748
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB	ChEA Transcription Factor Targets	1.0	null
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60522
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37672
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.659
GSE210885_0_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902033
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
endosomal part	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129163
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21967
icSARA deltaORF6_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.71067
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993441
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02021
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7584-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2828-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pentamidine (isethionate)_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.013172
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-486-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19412
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.17214
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.91093
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR751	CCLE Cell Line Gene Expression Profiles	1.0	1.43424
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1777
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ENHANCED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_3_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
MCF7_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135351
CRCGN015_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09175
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65154
ATF2	ENCODE Transcription Factor Targets	1.0	null
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30067
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Meloxicam_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0412325
Perturb_2369_KD_PRPF8_ERP008458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Obatoclax Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134093
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80805
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206418
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00152
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10675
Afatinib_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0386318
SMC3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1079-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2859
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62136
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923642
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.346
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5359
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.836729
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03496
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H520	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.40315
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIN28B_01_153	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.11675
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-3133	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2581
HS294T_SKIN	CCLE Cell Line Proteomics	1.0	5.28964
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38528
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.77232
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835646
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927394
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07604
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35925
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50136
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10366
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358286
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0371
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.12136
MYCN	ChEA Transcription Factor Targets	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.08584
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25731
RNF2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08902
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05028
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diclofenac_oncorhynchus mykiss_gpl10704_gse23053	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02591
hsa-miR-146b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PSS008	DepMap CRISPR Gene Dependency	1.0	2.89225
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974938
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYO1	DepMap CRISPR Gene Dependency	1.0	2.84291
NALM6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.54139
MCF7_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165787
19505326-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
LCAM1	DepMap CRISPR Gene Dependency	1.0	2.39734
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43398
A549_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162926
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34184
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882035
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131699
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20277
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06705
K562_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166036
Baicalin_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.015041
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MCF7_AR-42_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00929767
MCF7_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190793
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30446
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-581-ZNF878_ZNF878	Rummagene Transcription Factor Associations 2026	1.0	null
Hoxc13_OE_GDS1890_174_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95575
Perturb_120_KD_Ywhaz_SRP045772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.7376
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HLFA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68461
hsa-miR-605	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08558
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966859
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42092
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25206
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A204	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25184
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1837
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3812
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01441
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3829
CRCGN017_MCF10A.WT.HP_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04835
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39203
GSE212299_3_v_0_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX3-20139965-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10795826-jciinsight-8-170518-s128.xlsx-Fig_5B-Gene_Regulated_by_VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0744
hsa-miR-3668	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.68428
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984348
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.1617
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0557
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.967192
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879796
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61164
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46704
GSE143643,GSE143644_3_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ONDA9	DepMap CRISPR Gene Dependency	1.0	3.232
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.16142
CAL148	CCLE Cell Line Gene Expression Profiles	1.0	1.89025
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1263	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3303
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947231
K562_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147523
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07139
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72786
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-107	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07117
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75378
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior frontal gyrus, opercular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11998
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16461
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05756
MCF7_TGX-221_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133943
MRTFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0573
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2124
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44759
GSE114015_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35936
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZZ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3037
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941905
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17814
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2633
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc2.xlsx-3_ASCL1_high_subtype-Gene_Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
fungal-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.46883
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89762
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4669	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836365
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.53628
PPARG	ChEA Transcription Factor Targets	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267645
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_6Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36047
Antigen processing: Ubiquitination & Proteasome degradation	Reactome Pathways 2024	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852136
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35453
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97843
MFE296	DepMap CRISPR Gene Dependency	1.0	3.46879
RCOR3	ChEA Transcription Factor Targets	1.0	null
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830008
synapse part	GO Cellular Component Annotations 2015	1.0	null
STAT1_01_154	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59312
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85657
CCNT2	ENCODE Transcription Factor Targets	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05773
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8247
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18031
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	2.19191
GSE93309_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gata3_22922362_treg_cd4poscd25posyfppos_lof_mouse_gpl8321_gse39864	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.015767
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5994
Perturb_15138_KO_Nlk_SRP259678	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68149
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1072
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2199
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59718
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16822
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH596	CCLE Cell Line Gene Expression Profiles	1.0	1.53087
ion binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02655
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645813
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02542
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62641
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34534
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
NR1I2	ChEA Transcription Factor Targets	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3706
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22279
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67727
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42798
hsa-miR-1269b	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-556-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC9362915-pone.0272017.s004.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74271
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.581758
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Resminostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148935
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2015	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-36-FY37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214036
ovary	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843668
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2164
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2753
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994733
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77753
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66178
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Enzastaurin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156685
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2741
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4177
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7037
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5952
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28237
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3554
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06627
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18893
MCF7_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146587
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9263
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20976
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0534
POU2F2	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4448	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
SOX2	ChEA Transcription Factor Targets	1.0	null
GSE162688_3_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-499-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982488
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00467
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27004
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24324
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.07911
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44587
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02433
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A6JB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EZH2	ChEA Transcription Factor Targets	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15286
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.84731
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2358
Prostate adenocarcinoma_PRAD_TCGA-EJ-5495-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03728
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926781
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45894
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870858
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3833
SNU119_OVARY	CCLE Cell Line Proteomics	1.0	4.09498
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19193
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63593
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1378
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03229
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11061
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56355
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.982
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40303
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94961
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0362
Vitamin K4_Hs 766T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00484743
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5865
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34838
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1266
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU1105_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.81682
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67811
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896973
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24378
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58649
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0436
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC893	CCLE Cell Line Gene Expression Profiles	1.0	1.44545
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NUAK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0948
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40827
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A2PC-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Canagliflozin (hemihydrate)_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0100028
MCF7_BRD4770_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200637
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL5947 (ZNRF2)	NURSA Protein Complexes	1.0	null
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07306
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865871
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.656923
PHC1-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_Tie2 kinase inhibitor_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169104
lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A4-FUK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP212	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65534
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.03603
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85088
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.715257
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.144232
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48535
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.87231
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51267
K562_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187531
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1275
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875047
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO205	Achilles Cell Line Gene Essentiality Profiles	1.0	1.36736
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19834
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4925
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE510_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.50554
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864092
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27034
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21609
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851441
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9608
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0125
MCF7_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161645
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27496
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
RSV-A2_24Hour-B6.129PF1_J_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79787
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855723
GSE119498_2_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18511
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47419
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.099971
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dimethylfraxetin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.74156
MCF7_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140344
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE222500,GSE222501_1_v_0_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12078
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411245
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97621
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43225
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01895
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984564
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34238
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.899
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9265
Perturb_9603_KO_Satb2_SRP328167	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.66747
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44467
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A631-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-80-DI95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224786
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4420	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
MCF7_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0108576
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0703
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03023
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IH-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
SMAD2	ChEA Transcription Factor Targets	1.0	null
hsa-miR-620	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.631858
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49193
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.939674
HS739T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4802
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8472
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.55327
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6193_KO_Eed_SRP133646	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
496100571_FWM_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11401
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07116
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903177
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63699
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08732
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3295
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3082
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65523
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RIPK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.86526
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lysosomal membrane	GO Cellular Component Annotations 2015	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03895
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932152
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20008
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47327
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11166
klf9_17379758_jejunum_lof_mouse_gpl339_gds2703	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.17029
Cystic Fibrosis_Lung_GSE3100	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.5247
Nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55631
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34201
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59948
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.6562
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14766
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867269
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05639
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37352
Olodaterol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.930059
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.84364
PMC10290283-biol-2022-0622-sm3.pdf-103-GPBP1_GPBP1	Rummagene Transcription Factor Associations 2026	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42798
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949699
hsa-miR-503	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Resveratrol_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0400116
MCF7_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137133
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07609
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9242
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24291
protein polyubiquitination	GO Biological Process Annotations 2023	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17668
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06887
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64843
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925478
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32121
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51422
SARS-BatSRBD_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8205
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-BatSRBD_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.15761
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06543
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58099
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRSK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
hsa-miR-451b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.856697
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHC1	ChEA Transcription Factor Targets	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.093352
MCF7_Busulfan_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0232224
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38613
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8461
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18779
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17747
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_8_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5311
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141079
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39555
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01262
MCF7_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197236
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4716-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14876
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995413
liver	GTEx Tissue Gene Expression Profiles	1.0	0.885566
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3193	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.873879
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07577
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.357086
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927164
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS2_KD_GSE62168_259_mouse_mouse trophoblast stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900625
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.60601
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911327
SNU387	DepMap CRISPR Gene Dependency	1.0	2.16026
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35749
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997054
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_SNS-314 Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00999946
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15242
BATF	ENCODE Transcription Factor Targets	1.0	null
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.77046
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61965
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18324
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38127
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12171002-jcav16p2578s1.pdf-66-BNC2_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05751
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.1641
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLC-PRF-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
hsa-miR-339-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1614
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14655
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868941
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876988
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1808
MCF7_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149216
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43055
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0952
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63454
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-891b	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-324-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29359
HCFC1	ENCODE Transcription Factor Targets	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05579
hsa-miR-3944-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67171
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882632
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34484
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03594
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18423
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8708
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31279
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08352
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873875
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-503	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZNF735	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10517
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27352
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57334
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.01663
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34903
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14186
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4330	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
UBE2D2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
proteasomal protein catabolic process	GO Biological Process Annotations 2025	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03187
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11114
colon	GTEx Tissue Gene Expression Profiles	1.0	1.04961
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein modification by small protein conjugation	GO Biological Process Annotations 2015	1.0	null
GSE171724_1_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02289
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43203
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.35345
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.0842
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04098
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51031
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.027
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
D-542MG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.2955
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53681
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	2.17484
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YI-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32789
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869165
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12932_KD_DHODH_SRP340404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.33484
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4782-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10199
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857271
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849956
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42394
NCIH2110	CCLE Cell Line Gene Expression Profiles	1.0	1.65501
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
N6022	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226062
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	5.62529
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942911
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71955
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8102197-41375_2021_1146_MOESM2_ESM.xlsx-genelists-MOLM13_ChIP_DOT1L_VTP_Dn_150_Krivstov_et_Al_DOT1L	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21222
K562_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178932
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83237
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56352
SNB19_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.73341
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27365
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16782
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52533
Corpus cavernosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
SAP30	ENCODE Transcription Factor Targets	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43097
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19264
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.23673
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
sirolimus_rattus norvegicus_gpl1355_gse19366	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15349
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
FAM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16396
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18245
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38953
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5429
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97916
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228286
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950186
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06543
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985581
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164282
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113539
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882632
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72188
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.114577
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909047
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69712
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10145
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03272
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06058
PMC12486367-Supplementary_Data2.pdf-397-MYNN_MYNN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60721
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26897
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.686
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08415
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851905
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03157
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
19837975-TableS1	GeneSigDB Published Gene Signatures	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60196
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4268	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.910343
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09408
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02132
CHD1	ChEA Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1435
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
precentral gyrus, left, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04171
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19796
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6953-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829334
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.55907
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24937
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.720204
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111061_1_v_3_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13661
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40495
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.964341
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251595
RERFLCSQ1_LUNG	CCLE Cell Line Proteomics	1.0	4.22622
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942755
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52949
positive regulation of vesicle fusion	GO Biological Process Annotations 2025	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918001
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.608307
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VMRC-RCW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.571
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.31349
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.33247
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20481
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.864143
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74484
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0204
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11595
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81286
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.7804
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15617
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5101
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H1_Derived_Mesenchymal_Stem_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.29867
NCI-H69	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.23636
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832262
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94805
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906282
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21361
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1569
BCL3	ENCODE Transcription Factor Targets	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.887305
TCF3	ENCODE Transcription Factor Targets	1.0	null
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.11283
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Proteinuria	CTD Gene-Disease Associations	1.0	1.12634
GSE169356_2_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
SNU398	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6226
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3729
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63078
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986913
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rosiglitazone_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00646665
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914316
CCC5	DepMap CRISPR Gene Dependency	1.0	5.1524
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77711
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27556
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20932
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
contexts	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68503
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3715
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894469
SOX9	ChEA Transcription Factor Targets	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-101	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Perturb_4464_KO_Bicc1_SRP043577	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.82409
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15775
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35232
endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPL_02_160	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60855
hsa-miR-4524	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922786
hsa-miR-4427	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.692537
GRHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49735
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03885
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Sorafenib Tosylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186423
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2991
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF217	ChEA Transcription Factor Targets	1.0	null
A1207	Achilles Cell Line Gene Essentiality Profiles	1.0	1.20502
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1487
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.4532
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_JNJ-7706621_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140515
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
TBX3-20139965-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43526
hsa-miR-374a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0299
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934734
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.925769
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48595
RVH421_SKIN	CCLE Cell Line Proteomics	1.0	3.48864
cytoplasmic vesicle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30257
CRCGN015_MCF10A.WT.HP_24H:A23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29842
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56801
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34611
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934519
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52564
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19957
Necrosis	CTD Gene-Disease Associations	1.0	1.6993
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24322
neuron part	GO Cellular Component Annotations 2015	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48214
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05105
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24104
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.39605
BT474	CCLE Cell Line Gene Expression Profiles	1.0	1.56135
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221171
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
AN3CA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85084
A549_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011794
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5031867-mmc2.xlsx-RYTTCCTG_V_ETS2_B-PROBE_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14095
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61324
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931692
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85595
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06302
MCF7_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142319
4,4'-Dimethoxybenzil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12850_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.06934
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT55	Achilles Cell Line Gene Essentiality Profiles	1.0	1.30885
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47632
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63257
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lytic vacuole	LOCATE Curated Protein Localization Annotations	1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CHD1	ENCODE Transcription Factor Targets	1.0	null
Perturb_9553_KO_Akt2_SRP101985	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5099
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910018
icSARA deltaORF6_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.17659
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21766
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Hypertrophy	CTD Gene-Disease Associations	1.0	1.17202
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37134
A549_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145837
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48979
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994136
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2358
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231215
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7034
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1288	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MARK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3120-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A4EI-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12849_KO_Rnf114_SRP301146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82195
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92827
WD-62-UB45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24444
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09482
DA-58-LZ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32315
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1565
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.26516
MDAMB436_BREAST	CCLE Cell Line Proteomics	1.0	2.57848
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06842
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200292
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43895
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12455
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11665843-SYB2-18-218-s001.pdf-141-ZBTB10_ZBTB10	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphatic Diseases	CTD Gene-Disease Associations	1.0	1.18521
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Tazarotene_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00795671
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00274
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
SC-187 (ATF2)	NURSA Protein Complexes	1.0	null
L-NIL	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18916
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF1	ENCODE Transcription Factor Targets	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.926341
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17859
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3072
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-3909	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Rucinol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.49
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27004
CH157MN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84421
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39704
CRCGN015_HEPG2_48H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20783
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.17395
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Pyrophosphate	HMDB Metabolites of Enzymes	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06887
icSARS CoV_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77278
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.08731
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MCF7_Roscovitine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162532
MEF2A	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09242
CAS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.25145
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881591
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1482
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.38826
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95598
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
ED-81-ZH14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23447
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37812
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56766
GSE142684_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9911396-41467_2023_36178_MOESM11_ESM.xlsx-Sheet1-Genes_in_10kb_vicinity_of_ZBTB12_ChIP-seq_peaks_ZBTB12	Rummagene Transcription Factor Associations 2026	1.0	null
PITX2_01_55	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.83703
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.275
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98095
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UA-39-TN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320936
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51345
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29125
NCIH441	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1715
MCF7_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235114
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HuTu-80	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.20955
MM485	DepMap CRISPR Gene Dependency	1.0	2.32299
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38001
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826791
Rapamycin vs Ctrl_Exp2_MEFs (Mouse) [21659605]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0881
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0019
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218098,GSE218099_1_v_0_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69087
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1552
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92214
MCF7_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117973
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7809
CAOV3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.57169
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12789
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25291
NFYA	ENCODE Transcription Factor Targets	1.0	null
Retinitis Pigmentosa_Retina_GSE128	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.776
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906032
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15624
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858102
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960527
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
levetiracetam_rattus norvegicus_gpl1355_brainstem_gds1864	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25075
Hepatic primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
KYSE-50	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.45843
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13819_KO_YBX1_SRP222969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.39165
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867749
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945263
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15201
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MELK_druginhibition_186_GSE50227	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.3128
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07898
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67479
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53804
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15292
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1623	CCLE Cell Line Gene Expression Profiles	1.0	1.89106
CLOCK-20551151-293T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.176056
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19132
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rucaparib (phosphate)_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0161616
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05297
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15131
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.33483
SOX2-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7196
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58903
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43091
MCF7_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154407
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45287
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Adenosine triphosphate	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6775-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954769
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79074
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10205
GSE112860_9_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.16
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.44165
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-6720-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96492
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97489
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836169
ATF3	ENCODE Transcription Factor Targets	1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27861
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genistein	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836971
GSE95826_4_v_1_tcra_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17962
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein K48-linked ubiquitination	GO Biological Process Annotations 2023	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97228
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889643
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967121
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03336
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57973
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17099
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14746
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952808
hsa-miR-4310	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3227
hsa-miR-4781-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882632
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00602602
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981631
GSE111102,GSE111105_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51629
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866102
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044425
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43121
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	3.0913
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18088
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vacuole	LOCATE Curated Protein Localization Annotations	1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17666
Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02134
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3064-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
SKMES1	CCLE Cell Line Gene CNV Profiles	1.0	1.40822
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17797
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92179
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1305	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.65674
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12626
GABPA	ENCODE Transcription Factor Targets	1.0	null
MCF7_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186697
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54064
PMC10350077-media-8.xlsx-PPM1D_tr_LPS_vs_Cont_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217101_0_v_1_mcph1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98887
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1252
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5029
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06314
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25157
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77007
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35352
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218475
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998075
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.992655
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.02596
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11714
PMC11399095-44161_2024_532_MOESM7_ESM.xlsx-Sheet1-Supplementary_Table_6_DEG_of_hyperexpanded_clones_in_EAT_vs_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893186
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30968
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10067
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64653
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1486
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88077
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00497
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18104
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66208
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64288
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1472
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32125
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
aire_21746930_treg_cd8pos_cd28low_lof_mouse_gpl6246_gds4373	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.74516
AF4-28076791-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diphenhydramine_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0414452
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.91664
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74508
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16636
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15756
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHC1-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52331
SUZ12	ChEA Transcription Factor Targets	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1015
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045606
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980464
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06037
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.177154
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0241
Class I MHC mediated antigen processing & presentation	Reactome Pathways 2024	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87139
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56545
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222641
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09862
organelle part	GO Cellular Component Annotations 2015	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5637904-PATH-243-193-s015.xlsx-human_up_in_ductal_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.514
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-299-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14778
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.07681
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72287
JUND	ENCODE Transcription Factor Targets	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873273
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KD	DepMap CRISPR Gene Dependency	1.0	2.51166
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990033
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.838119
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963746
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93076
SP4	ENCODE Transcription Factor Targets	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847765
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7243-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10242447-mmc2.xlsx-TI_DEGs-Table_S1_TIGs_Comparison_between_each_trained_monocyte_sub-population_T3m_LPS_with_monocytes_T0_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52143
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.062
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18946
cd4.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0792
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51838
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164463_3_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21549
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54425
tcof1_15522210_neuroblastoma_gof_mouse_gpl339_gds998	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.651297
AR	ChEA Transcription Factor Targets	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72611
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53585
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18086
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.07115
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DV90	CCLE Cell Line Gene Expression Profiles	1.0	1.39752
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
K562_AMG-900_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014819
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12626
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138714
Perturb_5213_KO_Terc_SRP156128	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hFOB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834305
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11724
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02745
cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5625-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63315
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33878
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_ENMD-2076 L-Tartaric acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141403
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38974
ubiquitin protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61087
SKUT1	DepMap CRISPR Gene Dependency	1.0	7.22242
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949695
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834122
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58037
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15902
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.79549
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_10199_KD_RUNX1/RUNX1T1_SRP291095	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.97914
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53223
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82413
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-00-IL62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312531
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11364504-41388_2024_3115_MOESM2_ESM.pdf-202-ZIC4_ZIC4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32479
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12722
Lumateperone (tosylate)_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0266379
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06539
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53553
NANOG	ChEA Transcription Factor Targets	1.0	null
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645821
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60002
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5087
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
4-Benzylpyridine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Erlotinib_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00913005
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53484
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883602
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836495
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29818
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47791
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846938
hsa-miR-219-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_TAK-901_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126015
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230283_1_v_0_birc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82619
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15695
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.11535
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44613
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.74156
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29085
A549_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177411
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03469
IRF4	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03254
HCC1419	CCLE Cell Line Gene Expression Profiles	1.0	1.35897
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.57947
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74217
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92179
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32624
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3004
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0171
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85037
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGK2	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.7
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A498-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92827
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.2974
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914326
GFI1B	ChEA Transcription Factor Targets	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157484
GW7647	DeepCoverMOA Drug Mechanisms of Action	1.0	0.55
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15846
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06601
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12918
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52295
UBE2O	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34182
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_12934_KD_DHODH_SRP340404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.26449
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951137
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138318
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43246
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22852
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848223
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16443
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT1376_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	6.83413
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.59422
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cinacalcet_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0287385
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16968
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.209
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B4-01A-12R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H446	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.92752
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21016
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02321
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980466
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61512
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2N	Pathway Commons Protein-Protein Interactions	1.0	null
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.036532
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49796
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054262
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.3988
u266	HPA Cell Line Gene Expression Profiles	1.0	1.53021
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74122
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5743
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23627
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156983
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
PMC10322668-Table_7.xlsx-DE_genes_at_early_infection-List_of_de-regulated_genes_at_early_interaction_time_point_of_Dm28c_T_cruzi_THP1_infected_cells_From_Libisch_2020_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0409
ELF1	ENCODE Transcription Factor Targets	1.0	null
0min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36166
UACC-62	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.58128
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49997
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12024
MEF2A_KD_GDS4759_340_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02795
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917728
Altretamine_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.023007
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBX3	ChEA Transcription Factor Targets	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66937
SPI1	ChEA Transcription Factor Targets	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155269
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.198991
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854977
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10733
ERG-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
hsa-miR-3668	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Raltitrexed_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0248071
20860821-TableS5	GeneSigDB Published Gene Signatures	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.18589
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.275
CJ-42794	DeepCoverMOA Drug Mechanisms of Action	1.0	0.57
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969026
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.96483
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.610042
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09902
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01057
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74835
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.3013
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266408
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37706
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08294
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67032
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
RKO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37898
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F6-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9175
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012968
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08913
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26352
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907204
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3655	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48551
DA-10-ZX00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436571
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0232
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12716
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC5637904-PATH-243-193-s015.xlsx-human_up_in_ductal_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39515
BT16	DepMap CRISPR Gene Dependency	1.0	10.0748
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57762
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14769
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5956
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.129489
LOXIMVI_SKIN	CCLE Cell Line Proteomics	1.0	2.65087
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
8305C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48953
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280737
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0288
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB-224289	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.71
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1072
TTC709	DepMap CRISPR Gene Dependency	1.0	11.5446
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162839
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35496
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25555
Detroit-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967947
IRF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100588_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50914
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08161
K562_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0252132
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-50-ZNF77_ZNF77	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.43285
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.057829
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07766
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04742
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97213
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.90771
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23228
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852435
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21876
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23529
IRF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09828
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39371
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86316
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3885
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66287
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91447
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278004
Perturb_6228_KO_Mbnl1/Mbnl2_SRP142522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.09302
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82642
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10421
CRCGN015_HEPG2_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04706
intracellular part	GO Cellular Component Annotations 2015	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.4056
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64242
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949167
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264192
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4796-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SP2	ENCODE Transcription Factor Targets	1.0	null
Bergenin_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.018385
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09929
SKNO1	DepMap CRISPR Gene Dependency	1.0	3.39304
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CLOCK	ChEA Transcription Factor Targets	1.0	null
Perturb_10418_KD_Nuak1_ERP105467	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.91706
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7983
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MET_knockout_260_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.62946
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35962
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10289
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052513
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5149-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855092
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31091
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72808
Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3453
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02703
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1459
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03484
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13572
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
Fibrillar center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Alveolar lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
MCF7_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141826
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSN1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07376
CUX1	ENCODE Transcription Factor Targets	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15926
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.3581
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1045
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-32-RF17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233844
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89637
10min_PPase_inhibitors vs ctrl_Hepa1-6 (Mouse) [18846507]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85748
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913836
CAOV-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.49065
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10484
hsa-miR-548m	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.34083
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.917325
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896927
CTBP2	ENCODE Transcription Factor Targets	1.0	null
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06924
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42487
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991133
PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00706
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2193
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5535
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2834
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60655
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC827GR5	DepMap CRISPR Gene Dependency	1.0	2.39186
MAX_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96247
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20104
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	1.0	0.94246
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
changing	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22248
SARS-CoV MA15_Day7-CXCR3KO_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75631
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.927957
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03222
hsa-miR-99b	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15842
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44161
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11283
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844581
Zinc finger, RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAK2_druginhibition_168_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52557
CHD7	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.37859
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMG 487	DeepCoverMOA Drug Mechanisms of Action	1.0	0.59
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72705
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.951696
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.898194
Hyperplasia	CTD Gene-Disease Associations	1.0	1.01249
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1196	DepMap CRISPR Gene Dependency	1.0	2.08694
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012946
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.867162
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4275	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924302
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.882897
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1306
OELE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.41241
NFATC1	ENCODE Transcription Factor Targets	1.0	null
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42687
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-54-ZNF251_ZNF251	Rummagene Transcription Factor Associations 2026	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211963_0_v_3_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null