association dataset threshold value standardized value EWSR1 ChEA Transcription Factor Targets 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5553-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7086-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13958 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE128634,GSE128636_4_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OVMIU DepMap CRISPR Gene Dependency 1.0 5.73074 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.93951 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2669 Diagonal band nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25819 protein self-association GO Molecular Function Annotations 2015 1.0 null REEP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05389 Ventral tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17266 VMRCRCZ CCLE Cell Line Gene CNV Profiles 1.0 1.44953 DYNC1LI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8316 H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08061 AGTPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69208 REL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46616 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3509 ZNF780B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69953 posterior (ventral) nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00542 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21513 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null Enteroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.883 Pulmonary hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.319 C19orf12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77718 MYO1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76691 Spine apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.797 HSPG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3176 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.973 ChIP_GLI1_17442700 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null C14orf28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37053 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 LNZ308 CCLE Cell Line Gene Expression Profiles -1.0 -2.0984 ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE154350_1_v_0_ascl2_human RummaGEO Gene Perturbation Signatures 1.0 null EPLC272H CCLE Cell Line Gene Expression Profiles 1.0 1.83059 Anterior olfactory nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18735 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF71 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00824 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE160817_4_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null regulation of signal transduction GO Biological Process Annotations 2015 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC Rummagene Transcription Factor Associations 2026 1.0 null ATP6V0A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07681 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06494 Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE118765_1_v_5_rreb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Infantile hypophosphatasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.685 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Primary somatosensory area, trunk, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0924 GSE202603_1_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cul7-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.613 layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46702 C1orf174 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60358 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.978471 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GATA1_G1E-ER4_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25352 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.91079 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050613 SKNFI CCLE Cell Line Gene Expression Profiles 1.0 1.76453 H2BK120ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52394 GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2669 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07368 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOS COSMIC Cell Line Gene Mutation Profiles 1.0 null DMS-53 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 BIRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73755 H4K5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45414 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19637 ASH-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4793-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 hsa-miR-548c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE235234_2_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18708 cSARS Bat SRBD_12Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.36046 vertical nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26289 PC14 CCLE Cell Line Gene CNV Profiles -1.0 -1.82977 WASF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.60941 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1967 CDX2-20551321-CACO-2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.0762 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SCRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83542 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TDOTT DepMap CRISPR Gene Dependency 1.0 2.1581 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01104 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null RP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1202 Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18364 Variola minor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP Rummagene Transcription Factor Associations 2026 1.0 null 496100659_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06451 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.845394 PPARD ChEA Transcription Factor Targets 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02856 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45848 Hypodermal seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.925 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.4125 Malpighian tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.816 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4748 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 PAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23902 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8918 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE168587,GSE168752_3_v_1_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null JHOM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.73648 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYM1 DepMap CRISPR Gene Dependency 1.0 4.85976 KNS42 CCLE Cell Line Gene Expression Profiles 1.0 1.41709 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F2_01_07 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.8059 KLF7_KO_GDS2069_68_mouse_olfactory epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.893411 SLC29A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92973 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6949 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Loin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.771 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 hsa-miR-4464 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1 Rummagene Transcription Factor Associations 2026 1.0 null HASPIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68982 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21438 Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63227 POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055404 Mucilage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.87 CREB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94741 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-328-ZNF597_ZNF597 Rummagene Transcription Factor Associations 2026 1.0 null Placenta disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.196 amygdaloid complex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58861 MAGEA11 Pathway Commons Protein-Protein Interactions 1.0 null positive regulation of apoptotic signaling pathway GO Biological Process Annotations 2015 1.0 null HSFY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17109 SKNMC DepMap CRISPR Gene Dependency 1.0 2.19096 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.908 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16591 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36841 SF3A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00917 NQO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80167 EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93867 HPAEC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.532 H3K27me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ubiquitin-protein transferase activity GO Molecular Function Annotations 2015 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CBX2 ENCODE Transcription Factor Targets 1.0 null binding GO Molecular Function Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4327-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8083 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null UBC Pathway Commons Protein-Protein Interactions 1.0 null cervical cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.766954 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3099 lateropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1532 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2167 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5714 IFNLR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61181 Zinc finger, RING/FYVE/PHD-type InterPro Predicted Protein Domain Annotations 1.0 null BT20 CCLE Cell Line Gene CNV Profiles 1.0 1.41121 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74073 SMIM30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71257 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Thymic medullary epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.645 GNG13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64333 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90085 TMEM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66486 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C2BBE1 DepMap CRISPR Gene Dependency 1.0 3.18101 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068133 GSE94768_3_v_2_pofut1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF384_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MME CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75507 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNAJC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13568 Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF763 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91784 PCYT1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38653 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.03351 PARD6G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07619 ZNF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16433 brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.895211 H2BK12ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60217 cell death GO Biological Process Annotations 2015 1.0 null skin GTEx Tissue Gene Expression Profiles 1.0 1.10477 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.9402 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4653-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 TNFSF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19886 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -2.62957 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zinc finger, SWIM-type InterPro Predicted Protein Domain Annotations 1.0 null CHP126 CCLE Cell Line Gene CNV Profiles 1.0 1.43042 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.825226 cervical cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.76157 ZKSCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19318 GDPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6012 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A821-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8107 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35084 FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.969261 ASPC1 DepMap CRISPR Gene Dependency 1.0 3.24601 Stroke HuGE Navigator Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A46R-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42019 r10 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33163 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null GSE241701_4_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null YAPC CCLE Cell Line Gene Expression Profiles -1.0 -1.58864 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.90823 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67992 MAX ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052462 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.211 OC314 CCLE Cell Line Gene Expression Profiles -1.0 -2.73046 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RD CCLE Cell Line Gene CNV Profiles 1.0 1.59295 MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsomedial nucleus, terminal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68165 hsa-miR-3671 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 CHD2 ENCODE Transcription Factor Targets 1.0 null RTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60959 H4 CCLE Cell Line Gene Expression Profiles -1.0 -2.6918 JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 19505326-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBC1D17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44925 EPHA4_knockout_226_GSE34430 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.31116 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.82644 ZNHIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50359 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54302 retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60585 H3K27me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Primary somatosensory area, lower limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27375 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065839 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47705 GSE235701,GSE261434_0_v_1_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10053 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.8837 cell part LOCATE Curated Protein Localization Annotations 1.0 null CDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37921 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.40361 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.35605 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null icSARA deltaORF6_48Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.43637 H3K27me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3248 ZC3H7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72091 basal part of terminal hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79721 RGS14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97119 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.85047 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82707 Ventral premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37978 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18417 JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4358 GSE220600_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82646 tcf12_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.038613 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mp88 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.831 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.831971 ESR1-22446102-UTERUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null transferase activity GO Molecular Function Annotations 2015 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05698 Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pupa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.908 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RHOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25274 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.84 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01104 hsa-miR-181b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 STAT3 ChEA Transcription Factor Targets 1.0 null SLC25A45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92729 HS870T CCLE Cell Line Gene Expression Profiles 1.0 1.9027 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4427 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050421 USP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62768 Bejel DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.347 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO Biological Process Annotations 2015 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.0128 ZFP41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7474 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8695 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050954 Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07596 AP-2 adaptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.716 PMC10247733-41408_2023_863_MOESM2_ESM.pdf-582-ZSCAN18_ZSCAN18 Rummagene Transcription Factor Associations 2026 1.0 null Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36261 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r10 part of vagal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68222 superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.406 CFPAC1 DepMap CRISPR Gene Dependency 1.0 2.92883 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02969 ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HS3ST3B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93463 Parkinson's disease 15 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.566 RHOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31705 SETDB1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-4295 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZXDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42188 EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF4-18268006-LS174T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE226316_4_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855404 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.01699 periventricular stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03034 Nurse cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.099 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null clathrin-coated endocytic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.709 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25376 RCCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12788 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06831 CSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01652 GDF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6957 blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.081806 medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21289 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null DPY19L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70863 KYO1 CCLE Cell Line Gene Expression Profiles 1.0 1.95907 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.51107 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33948 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25376 TM31 CCLE Cell Line Gene CNV Profiles -1.0 -1.37307 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52225 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12288 ZNF420 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4481 single-organism cellular process GO Biological Process Annotations 2015 1.0 null SGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80324 hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16855 Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 ORC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77766 CHEK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18123 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71772 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HAUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7184 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POU3F2 ChEA Transcription Factor Targets 1.0 null SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64977 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.81524 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069624 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053678 B4GALT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12086 SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.6679 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7816 L363 DepMap CRISPR Gene Dependency 1.0 2.54898 WM-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LGMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50079 SLVL COSMIC Cell Line Gene Mutation Profiles 1.0 null periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67992 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SCC9 DepMap CRISPR Gene Dependency 1.0 3.08545 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051547 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 SKNAS CCLE Cell Line Gene Expression Profiles 1.0 1.48935 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.811006 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null KDM6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73208 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Mo-B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.713 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.919341 positive regulation of cell communication GO Biological Process Annotations 2015 1.0 null Sensorimotor area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.904 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9203 H3K27ac_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PSS008 DepMap CRISPR Gene Dependency 1.0 3.0158 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null positive regulation of signaling GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.25975 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HUT78 CCLE Cell Line Gene CNV Profiles -1.0 -1.98585 superficial stratum of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2206 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RBCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01482 ModE complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.83 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null COLO-741 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2126 CCLE Cell Line Gene Expression Profiles -1.0 -1.76486 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950298 AP2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00594 H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null APH1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79192 NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11632 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10129 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874431 MTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81502 FOS ENCODE Transcription Factor Targets 1.0 null H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null protein polyubiquitination GO Biological Process Annotations 2015 1.0 null protein modification by small protein conjugation or removal GO Biological Process Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH661 CCLE Cell Line Gene CNV Profiles 1.0 1.8016 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF333 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19761 KAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1603 Adrenocortical carcinoma_ACC_TCGA-OR-A5JQ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pre-eclampsia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.132 HUH7 CCLE Cell Line Gene Expression Profiles -1.0 -1.52914 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9266 CDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62242 Waist circumference adjusted for body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.739794 chr2_186852402_T_C_b38 GTEx eQTL 2025 1.0 1.01343 GSE128634,GSE128636_4_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null KARPAS-1106P COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ITGB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9817 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.877564 Acromelic frontonasal dysostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.393 Hypertension HuGE Navigator Gene-Phenotype Associations 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2868 Paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21251 intermediate part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41517 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02969 JHU011 DepMap CRISPR Gene Dependency 1.0 2.07239 FZD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87516 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CYFIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57434 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UMUC9 DepMap CRISPR Gene Dependency 1.0 2.77903 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH28 DepMap CRISPR Gene Dependency 1.0 5.34258 EMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05884 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48057 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64325 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100597_HIP_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.96802 TEAD4 ENCODE Transcription Factor Targets 1.0 null SNU840 CCLE Cell Line Gene CNV Profiles -1.0 -1.62849 GSE140441_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.668517 SLC35E2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99882 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4011 organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12693071-NIHMS2120882-supplement-8.xlsx-Sheet1-scWGS_analysis_of_the_M486_AR_model_AR-specific_or_-enriched_CNV_genes_involved_in_apoptosis_immune_regulation_and_or_known_ICI_resistance_pathways_AR Rummagene Transcription Factor Associations 2026 1.0 null icSARS-Cov_Day7_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.76208 ENDOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82452 H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Scape TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.015 H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CNOT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70434 UBALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17344 RPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48372 UBL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5852 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11093 H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21453 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Medial septal complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15014 retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1559 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0925 H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU449 DepMap CRISPR Gene Dependency 1.0 2.25985 OVCA420 DepMap CRISPR Gene Dependency 1.0 3.10785 positive regulation of cell death GO Biological Process Annotations 2015 1.0 null Superficial temporal vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.046 HUH1 CCLE Cell Line Gene CNV Profiles 1.0 1.4973 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null WFS1_KO_GDS4526_111_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SETDB1-19884257-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.71446 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null TDGF1P3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28345 Hip index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGBC24TKB COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 H3K27me3_iPS-15b Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65047 dorsal septopreoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31538 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDIT4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59285 superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41953 PCI-38 COSMIC Cell Line Gene Mutation Profiles 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86411 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4982-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Parataenial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29966 primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29413 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GET complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 hsa-miR-4280 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 ZSCAN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31775 LU65 CCLE Cell Line Gene Expression Profiles 1.0 1.54202 22RV1 DepMap CRISPR Gene Dependency 1.0 13.4155 ACY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54119 GSE226316_1_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ADAM17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1056 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.958966 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 Retrocerebral complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.008 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2469 ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9479 RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9732 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03564 CLDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61987 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAV3_Deficiency_GDS3552_558_mouse_Hearts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TNRC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84361 PAX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86071 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null perimammillary part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21453 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.46066 hsa-miR-130b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 INTS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6004 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.33299 mantle zone of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4198 STAT1 JASPAR Predicted Transcription Factor Targets 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE102870_11_v_9_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MEG-01 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 REST ENCODE Transcription Factor Targets 1.0 null icSARA deltaORF6_72Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.52033 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.02122 CELF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35214 macromolecule modification GO Biological Process Annotations 2015 1.0 null DDX53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27041 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21422 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2275 GSE196671_5_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Tongue muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.028 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0159 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17269_KO_Rfx2_SRP066176 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.1692 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.03624 PMC10951899-mmc1.pdf-7-ZNF804A_ZNF804A Rummagene Transcription Factor Associations 2026 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF4-18268006-LS174T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970216 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ESR1 ChEA Transcription Factor Targets 1.0 null ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7734 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null positive regulation of extrinsic apoptotic signaling pathway GO Biological Process Annotations 2015 1.0 null OVCA420 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TAFAZZIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93967 GLI1-17442700-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JUND JASPAR Predicted Transcription Factor Targets 1.0 null UBQLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40729 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SLC30A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10886 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08955 NCIH2110 CCLE Cell Line Gene Expression Profiles 1.0 1.4617 CAKI2 DepMap CRISPR Gene Dependency 1.0 2.23498 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NSUN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.777 HCC70 COSMIC Cell Line Gene Mutation Profiles 1.0 null LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3032 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.914485 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3161 SLC2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2517 Johanson-Blizzard syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.372 cellular process GO Biological Process Annotations 2015 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74224 POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4484 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38097 Orbital area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19331 SLC38A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31017 Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-3123 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Midgut epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.847 CDK18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39105 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57363 programmed cell death GO Biological Process Annotations 2015 1.0 null ASCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66053 RFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05043 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.89435 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Hypophosphatasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 SLC7A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30726 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.18443 OCUM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ASCL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82826 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17292 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7184 NADK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21889 LBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52327 A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.3395 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.951285 CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100503_HIP_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26928 MDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76759 TE-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 JUN JASPAR Predicted Transcription Factor Targets 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.926805 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09096 inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07032 r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03277 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ES8 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.03579 axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.239916 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null Cerebral Hemorrhage HuGE Navigator Gene-Phenotype Associations 1.0 null regulation of cell death GO Biological Process Annotations 2015 1.0 null BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.3909 E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHH TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.589 OLFML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4405 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39989 PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1 Rummagene Transcription Factor Associations 2026 1.0 null HCC515 DepMap CRISPR Gene Dependency 1.0 2.29527 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE246716_0_v_1_trappc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TOP2B-26459242-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FOXA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15058 ZNF766 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43293 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0299 OVCAR4 CCLE Cell Line Gene CNV Profiles -1.0 -1.43742 DNAJC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20519 H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH2342 CCLE Cell Line Gene CNV Profiles 1.0 1.49891 TCF12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7875-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Primary somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03715 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21761 PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 0.912934 AGAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77478 Median preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72208 superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1559 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KCTD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07083 SARS-CoV MA15_Day1_None_GSE49262 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.932752 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.1466 H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.649 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60438 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cervical carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.12368 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE63048_11_v_12_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Plantaris muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.652 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6252 cellular metabolic process GO Biological Process Annotations 2015 1.0 null PAX3 ChEA Transcription Factor Targets 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6911 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.63384 Acute Myeloid Leukemia_LAML_TCGA-AB-2914-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.903773 H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE153064,GSE153065_1_v_2_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null Posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59851 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.14373 FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.82038 TNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09588 mantle zone of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13512 r8 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04183 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null Intralaminar nuclei of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23862 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Psoas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.703 ZNF286A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49656 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A8BU-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.248578 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null PEX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77889 hsa-miR-3973 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 KMS12BM CCLE Cell Line Gene Expression Profiles 1.0 1.68394 Heterocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.626 COLO-679 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.7381 ion binding GO Molecular Function Annotations 2015 1.0 null SIRT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73302 SMAD4 ChEA Transcription Factor Targets 1.0 null KMH-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null PXDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25653 Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null catalytic activity GO Molecular Function Annotations 2015 1.0 null regulation of cell communication GO Biological Process Annotations 2015 1.0 null GSE235701,GSE261434_2_v_3_enasidenib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21692 GTF2F1 ENCODE Transcription Factor Targets 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8399 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15365 H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF677 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46827 Germinated grain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.876 Type III polyketide synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.689 JUND ENCODE Transcription Factor Targets 1.0 null DMS114 CCLE Cell Line Gene CNV Profiles -1.0 -1.35449 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TTYH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8048 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.828175 ASCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05557 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GALE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50989 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.39329 ELF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76532 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null HT144 DepMap CRISPR Gene Dependency 1.0 6.47636 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PANC0213 CCLE Cell Line Gene Expression Profiles -1.0 -1.93864 H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null A band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.807 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.762 RUNX2-24655370-MC3T3E1-MOUSE-BONE ChEA Transcription Factor Targets 2022 1.0 null NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.2582 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15056 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SF268 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43065 TRIM28_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null death GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MM1S CCLE Cell Line Gene Expression Profiles 1.0 1.44958 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3427 icSARA deltaORF6_60Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.68082 hsa-miR-607 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84664 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07049 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.874416 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09729 Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null nucleus LOCATE Curated Protein Localization Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular protein modification process GO Biological Process Annotations 2015 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42051 SJRH30 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91906 monolayer-surrounded lipid storage body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.12 UBE2N CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33787 hsa-miR-3148 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -2.20545 H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CDX2-20551321-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE128634,GSE128636_2_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18708 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4853 PRDM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17615 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.837306 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.177 DBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3495 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1658 Pulmonary fibrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.256 FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.1482 r9 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09254 L540 CCLE Cell Line Gene CNV Profiles 1.0 1.71972 BL2758 (MED17) NURSA Protein Complexes 1.0 null NB5 DepMap CRISPR Gene Dependency 1.0 2.17349 RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4920-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100653_PCx_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57052 Flotillin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.721 PAFAH1B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36333 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 Embryonic tracheal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.967 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1048 CCLE Cell Line Gene Expression Profiles -1.0 -2.07582 Oligohydramnios DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5633-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2A1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25113 DLX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7856 Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null p3 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15056 SH3BGRL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52884 CTCF ENCODE Transcription Factor Targets 1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null H3K9ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Field CA3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00963 hsa-miR-570 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Encephalitis, St. Louis DisGeNET Gene-Disease Associations 1.0 null Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054249 macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null periventricular stratum of r8Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04345 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40666 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DYNLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30951 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFP92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23625 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18813 C1orf159 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58835 H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HTR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68669 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p1 portion of the paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11632 KLF5-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SYT13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8566 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6483 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09729 DYNC1H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67025 A2780 CCLE Cell Line Gene CNV Profiles 1.0 1.58435 periventricular stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09334 intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23862 NCI-H1436 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Primary somatosensory area, unassigned Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2988 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.01699 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCCSUP CCLE Cell Line Gene Expression Profiles 1.0 1.48433 positive regulation of cellular process GO Biological Process Annotations 2015 1.0 null RAB40A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99315 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19377 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37873 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86162 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.70557 Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Peroxisomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.918 primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.891645 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IL27RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54101 ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7595 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CH157MN CCLE Cell Line Gene Expression Profiles -1.0 -1.75978 positive regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3391 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.75329 ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.824618 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.969261 icSARS CoV_48Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.07476 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51098 Pontine gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14147 DB CCLE Cell Line Gene CNV Profiles -1.0 -1.36258 ALOX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85915 JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus LOCATE Predicted Protein Localization Annotations 1.0 null HO-1-U-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mammillary body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1265 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TTLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23845 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29514 acute promyelocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.00763 Amnion epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.543 reuniens nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32748 HS604T CCLE Cell Line Gene Expression Profiles 1.0 1.60617 p1 part of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09294 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.99299 ZNF527 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55249 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1183 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07596 MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SERPING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20142 CCNF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89472 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.11676 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25376 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-130a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 NCIH1581 CCLE Cell Line Gene Expression Profiles 1.0 2.40871 H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PIP4P2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55512 Cul3-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.767 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20485 CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ES4 DepMap CRISPR Gene Dependency 1.0 5.0723 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DLX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34453 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93147 CRMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61004 CBS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45109 subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58446 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A2780 CCLE Cell Line Gene Expression Profiles 1.0 2.25263 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCI30 DepMap CRISPR Gene Dependency 1.0 2.06712 NCCSTCK140 CCLE Cell Line Gene CNV Profiles -1.0 -2.08209 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE139016_3_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null ATP11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56851 H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KIAA1522 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94048 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null sc1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.652 KCTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0813 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18735 hsa-miR-3140-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100392_HIP_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30335 GSE98755,GSE98756_1_v_0_fbxl19_mouse RummaGEO Gene Perturbation Signatures 1.0 null cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Primary somatosensory area, unassigned, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82646 apoptotic process GO Biological Process Annotations 2015 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU398 CCLE Cell Line Gene Expression Profiles 1.0 3.40796 SLR26 CCLE Cell Line Gene CNV Profiles 1.0 1.49132 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.3662 regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053713 medial part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1355 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null M band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.88 PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null MIM complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.286 HOXD12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5271 FAM161A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29615 DNAJB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4087 Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14642 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null GSE102870_3_v_9_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null TNFRSF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28211 superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21761 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CALR_KO_GDS3680_149_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null 786O CCLE Cell Line Gene Expression Profiles 1.0 1.73707 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE131161_2_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null DYNLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45842 Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 hsa-miR-454 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08769 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC Rummagene Transcription Factor Associations 2026 1.0 null ZNF285 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49043 r10 part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68504 KYSE30 CCLE Cell Line Gene CNV Profiles 1.0 1.7558 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.4591 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PBX3 ENCODE Transcription Factor Targets 1.0 null TMEM185B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48022 MG63 DepMap CRISPR Gene Dependency 1.0 2.23617 MM383 DepMap CRISPR Gene Dependency 1.0 2.2127 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.082 H2BC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08968 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4563 Hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 V-79 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.883 superficial stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93643 Thymic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.569 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PDF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.46588 H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYLK_knockdown_48_GSE14525 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.71505 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12986 NIBAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03398 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.968988 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02439 c91pl TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.756 Primary somatosensory area, unassigned, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2333 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.4567 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null GSE157960_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null MOGGCCM CCLE Cell Line Gene CNV Profiles -1.0 -1.44121 AARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65091 H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null WFS1_KO_GSE33372_395_mouse_hypothalamus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OCIP5X DepMap CRISPR Gene Dependency 1.0 2.25539 MAFF ENCODE Transcription Factor Targets 1.0 null hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072963 Subiculum, ventral part, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31778 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null NCI-H1993 COSMIC Cell Line Gene Mutation Profiles 1.0 null Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00004 hsa-miR-301b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943672 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lm10 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.139 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.610123 P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.775 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.993765 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Visceral muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.391 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null accessory entopeduncular nucleus (post-migratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15875 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Mediodorsal nucleus of the thalamus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14857 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.307167 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-339-RARA_RARA Rummagene Transcription Factor Associations 2026 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_1_GSC Rummagene Transcription Factor Associations 2026 1.0 null TCF4 ChEA Transcription Factor Targets 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45201 BICR78 DepMap CRISPR Gene Dependency 1.0 3.40697 GSE226316_11_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60626 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Omegae TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.662 Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5MZ-01A-21R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVKATE CCLE Cell Line Gene CNV Profiles 1.0 1.40275 Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16874 H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903475 NCI-H740 COSMIC Cell Line Gene Mutation Profiles 1.0 null EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41953 cell part LOCATE Predicted Protein Localization Annotations 1.0 null PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02969 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31859 hsa-miR-181d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-568 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077652 Molting gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.78 transition metal ion binding GO Molecular Function Annotations 2015 1.0 null METTL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44323 diagonal part of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73262 NCIH2227 CCLE Cell Line Gene CNV Profiles 1.0 1.51839 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34597 H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NRARP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5292 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.08848 SARS-CoV MA15_Day4-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.75458 MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89234 PRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91129 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7219 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15365 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.8504 PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null eGFP-FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ligase activity GO Molecular Function Annotations 2015 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.7876 Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.717581 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medial preoptic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15092 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42765 Muscle thin filament tropomyosin COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.168 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null lateral (parvicellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1339 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50068 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ISTMEL1 DepMap CRISPR Gene Dependency 1.0 5.16234 SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25356 PSN1 CCLE Cell Line Gene Expression Profiles -1.0 -1.48387 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3648 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100353_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.29367 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PL45 CCLE Cell Line Gene Expression Profiles -1.0 -1.85277 CERK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2735 CYB561 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84918 Subarachnoid Hemorrhage HuGE Navigator Gene-Phenotype Associations 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null fulvestrant_homo sapiens_gpl570_gse22533 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Primary somatosensory area, unassigned, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29148 GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null myeloid leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.521617 GSE122067_3_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SMARCA4 ChEA Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WHSC1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPIP5K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50307 APUD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.882 posteroventral (inferior) parietal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13498 HEC50B CCLE Cell Line Gene Expression Profiles -1.0 -1.74729 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.2269 KLF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09207 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81402 GSE85565_1_v_0_tcf21_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-3919 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Mesenchymal stromal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.497 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051913 GSE159937_1_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9927 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.07425 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TOV112D CCLE Cell Line Gene Expression Profiles 1.0 1.38811 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42765 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.3951 MKKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25097 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null pancreas HPA Tissue Protein Expression Profiles 1.0 0.737729 Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null ventrolateral part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50775 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45299 PPP1R26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30015 COLO-783 COSMIC Cell Line Gene Mutation Profiles 1.0 null regulation of apoptotic process GO Biological Process Annotations 2015 1.0 null H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GLI1 ChEA Transcription Factor Targets 1.0 null Septal area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.025 TBX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32169 UACC-812 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.869597 NCIH226 DepMap CRISPR Gene Dependency 1.0 2.32366 ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null JMJD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27113 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21453 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13388 PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null DMS53 CCLE Cell Line Gene CNV Profiles 1.0 1.94251 METTL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72314 PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2 Rummagene Transcription Factor Associations 2026 1.0 null TCEAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58548 core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61405 CHD7 ENCODE Transcription Factor Targets 1.0 null USP13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52277 PALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92898 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.89262 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97073 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.1448 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02969 ZNF232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31258 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4993-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41922 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87153 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25356 PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7695 Tuberomammillary nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2238 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6394 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MTHFS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15163 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cation binding GO Molecular Function Annotations 2015 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2211 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null PU1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EJM CCLE Cell Line Gene Expression Profiles 1.0 1.51682 TMPO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40155 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.63043 Posterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52906 H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100609_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0834 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ubiquitin-like protein transferase activity GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46219 NCIH1355 CCLE Cell Line Gene Expression Profiles 1.0 2.04778 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.302478 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.71377 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-181c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RNF213 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95653 positive regulation of programmed cell death GO Biological Process Annotations 2015 1.0 null Posterior parietal association areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7208 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null SJRH30 CCLE Cell Line Gene CNV Profiles 1.0 2.41099 H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAPGEF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95265 Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JURLMK1 DepMap CRISPR Gene Dependency 1.0 2.7315 ELAVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97737 GSE241701_4_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 1.71605 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null positive regulation of apoptotic process GO Biological Process Annotations 2015 1.0 null Lupus Erythematosus DisGeNET Gene-Disease Associations 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WASHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38145 hsa-miR-4272 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 hsa-miR-218 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZCWPW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36283 H3K4me1_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34703 posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24858 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00026 GSE160817_4_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null GMPPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74294 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.5442 MED16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89232 shell of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67536 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26137 GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null ST6GAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79533 MYC ENCODE Transcription Factor Targets 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.552 ELOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61931 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE196699_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null PPP1R11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64414 ZZEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0377 PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF Rummagene Transcription Factor Associations 2026 1.0 null BSPRY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82643 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null E2F6 ENCODE Transcription Factor Targets 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13396 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 SET2 DepMap CRISPR Gene Dependency 1.0 2.51565 Gonadal sheath cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.652 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4655-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Somatosensory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10892 P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RNASE6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47218 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.23205 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41042 periventricular stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68645 primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02899 H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LRATD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82559 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.88704 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null psi2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.514 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.39335 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 FOXM1-26456572-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18139 Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1559 H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00667 GSE224311_3_v_2_chaetocin_human RummaGEO Drug Perturbation Signatures 1.0 null ATPAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60504 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63199 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34307 DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ME1 CCLE Cell Line Gene CNV Profiles -1.0 -2.85986 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11632 Spermatoproteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.786 shell of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52373 H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null TP53I13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56761 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4619 organelle LOCATE Curated Protein Localization Annotations 1.0 null FOS_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89114 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 2.33269 uterine cervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.134445 Acute promyelocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.618 H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KM-8477-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gastric cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.453 Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ring gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.238 principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03852 basolateral amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03922 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4823-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00119 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pallidum, medial region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07744 DMS-79 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0821 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null Parafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38621 HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.979 GPR137 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9252 hsa-miR-543 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Amnion epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.52 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.67 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null CDX2 ChEA Transcription Factor Targets 1.0 null Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.344 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null HP1BP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33954 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IGROV1 DepMap CRISPR Gene Dependency 1.0 5.56576 GSE196671_6_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rad51B-Rad51C complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.548 CDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48134 TGFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39417 T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970216 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC14L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69977 PCI4B DepMap CRISPR Gene Dependency 1.0 2.10815 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Swine influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.179 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PCNX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41109 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05205 dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4229 hsa-miR-301a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null IPO8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9802 SNU216 CCLE Cell Line Gene Expression Profiles 1.0 1.48946 GSE211744_2_v_4_gdf15_mouse RummaGEO Gene Perturbation Signatures -1.0 null WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS618T CCLE Cell Line Gene Expression Profiles -1.0 -1.97173 Field CA3, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31624 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9279 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Golgi transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.27 Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17583 Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.08739 Allantoic fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.158 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2703 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02969 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acute myeloid leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.631931 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CXCR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75403 OAW42 DepMap CRISPR Gene Dependency 1.0 3.93714 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BCL2L13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17591 Posterior parietal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68781 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4824-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KALS1 CCLE Cell Line Gene CNV Profiles -1.0 -1.3309 ACOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07038 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9047 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.204 SOWAHC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02011 Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13958 GSE124410_6_v_4_stk40_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE234289_3_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null Subthalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25686 GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral premammillary nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61405 H3K9ac_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 TBP ENCODE Transcription Factor Targets 1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924439 Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10892 H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null protein metabolic process GO Biological Process Annotations 2015 1.0 null TMEM134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30439 TFDP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17772 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null METTL2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.50846 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.831823 RFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37717 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE128634,GSE128636_2_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE160817_5_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null terminal hypothalamus (rostral hypothalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7208 CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Hairy cell leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.684 hsa-miR-3666 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 superficial stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18479 NCIH2887 DepMap CRISPR Gene Dependency 1.0 3.40351 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Intracranial Hemorrhages HuGE Navigator Gene-Phenotype Associations 1.0 null Gracile nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25561 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DW-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4262 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 NCIH660 CCLE Cell Line Gene CNV Profiles -1.0 -1.50419 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911358 myeloid leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.284253 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3924 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.917689 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UBE2U Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Microbody lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.916 MYC-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 1.39853 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.844153 mantle zone of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73312 AMO1 DepMap CRISPR Gene Dependency 1.0 3.34405 ANGEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95186 Primary somatosensory area, lower limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01746 EBAG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73732 SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.8717 PTPRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45267 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH146 CCLE Cell Line Gene CNV Profiles -1.0 -1.48423 SERPINB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92333 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.873299 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.921887 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8508 RABEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98313 Clathrin coat of coated pit COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.715 YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null Interstitial lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.12 TMEM184B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17871 MAP7D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88292 NCIH196 CCLE Cell Line Gene Expression Profiles 1.0 2.13739 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39989 Albedo TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.921 ZNF503 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98105 NCIH522 CCLE Cell Line Gene Expression Profiles 1.0 2.65491 Pericarp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.916 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.911358 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, lower limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87309 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16783 anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01169 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sublayer 6b of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10189 HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.03624 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09086 regulation of programmed cell death GO Biological Process Annotations 2015 1.0 null NCIH1838 CCLE Cell Line Gene Expression Profiles 1.0 1.44295 PHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51546 hippocampus (hippocampal formation)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.956996 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Clathrin coat of endocytic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.716 GSE241701_2_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Type II site-specific deoxyribonuclease complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.001 Perireunensis nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14466 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07452 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Corpus cardiacum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.088 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9884 periventricular stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08061 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22352 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949078 RCCFG2 DepMap CRISPR Gene Dependency 1.0 3.46295 Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.68428 superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25352 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.955756 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13871 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02969 periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75884 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Amylin receptor complex 1 COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.713 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.59488 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YIPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95901 FBXO44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30117 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050985 layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11383 MST1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13356 suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38396 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178907_0_v_3_fkrp_human RummaGEO Gene Perturbation Signatures 1.0 null septopallidal part of the olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02661 WRNIP1 ENCODE Transcription Factor Targets 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 2.1884 Cleavage furrow COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.687 GCT COSMIC Cell Line Gene Mutation Profiles 1.0 null Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36261 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null regulation of extrinsic apoptotic signaling pathway GO Biological Process Annotations 2015 1.0 null HBEGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55319 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gut granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.351 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.930924 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76313 Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.052866 HH CCLE Cell Line Gene CNV Profiles -1.0 -2.36183 KRT19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41478 periventricular stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6813 central lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76249 ATR_KD_GSE54268_664_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RAMOS-2G6-4C10 COSMIC Cell Line Gene Mutation Profiles 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055064 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null H2AC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43353 Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54388 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 ventral striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07832 Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE189683_3_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.45932 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07537 ESR1-22446102-UTERI-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null EED CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41254 primary motor cortex (area M1, area 4)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0562 HT144SKINFV1 DepMap CRISPR Gene Dependency 1.0 4.16225 CELF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85325 Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65645 primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37466 Central lateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61579 EWS-FLI1-20517297-SK-N-MC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GGH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91359 AGS COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein ubiquitination GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47792 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.103672 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.874 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04839 Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.838842 Sarcoma_SARC_TCGA-DX-A23T-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81828 EP300 ENCODE Transcription Factor Targets 1.0 null UBXN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17196 UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intralaminar nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44171 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.0877 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TOLEDO CCLE Cell Line Gene CNV Profiles -1.0 -2.58176 Saccule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.745 regulation of signaling GO Biological Process Annotations 2015 1.0 null Nucleus of reunions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13868 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040464 regulation of extrinsic apoptotic signaling pathway via death domain receptors GO Biological Process Annotations 2015 1.0 null CD276 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89985 GLI1-17442700-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18051 COV318 CCLE Cell Line Gene Expression Profiles 1.0 1.52283 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00026 protein binding GO Molecular Function Annotations 2015 1.0 null 496100612_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5447 COV362 CCLE Cell Line Gene CNV Profiles 1.0 1.57108 corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214765 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-181a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17865 Amylin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.624 BAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66013 496100622_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.85344 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18416 protein modification process GO Biological Process Annotations 2015 1.0 null PIWIL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04908 TT CCLE Cell Line Gene CNV Profiles 1.0 2.14243 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PCGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90308 FOXP2 ChEA Transcription Factor Targets 1.0 null G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38877 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39686 SUMO activating enzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.647 NCIH1651 CCLE Cell Line Gene CNV Profiles 1.0 1.96096 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31859 H3K27ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MEIS1-26253404-OPTIC-CUPS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KCIMOH1 CCLE Cell Line Gene Expression Profiles -1.0 -1.51607 r3 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18401 TLR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18674 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null KOSC2 DepMap CRISPR Gene Dependency 1.0 2.77086 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ETS2_KD_GSE62168_259_mouse_mouse trophoblast stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MALME3M DepMap CRISPR Gene Dependency 1.0 2.19865 CHAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84205 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18813 EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16991 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72196 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00119 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60438 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.54257 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP2 ENCODE Transcription Factor Targets 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null STOML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92138 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8294 OLIG2 ChEA Transcription Factor Targets 1.0 null CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-458-MAFF_MAFF Rummagene Transcription Factor Associations 2026 1.0 null Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.88595 59M CCLE Cell Line Gene Expression Profiles -1.0 -2.12434 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062072 LUC7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01096 USF1 ENCODE Transcription Factor Targets 1.0 null GSE217541,GSE217543_3_v_2_tet1_human RummaGEO Gene Perturbation Signatures -1.0 null BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.545 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040359 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.8036 positive regulation of signal transduction GO Biological Process Annotations 2015 1.0 null H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAP1S CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64147 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6995-01A-31R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66127 RAD21 ENCODE Transcription Factor Targets 1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07976 h9c2(21) TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.699 Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.74357 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.941705 Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73086 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MARCKSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21782 tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60207 PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-774-ZNF705A_ZNF705A Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20909 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Anterior cingulate area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12833 intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18127 ZNF384 ENCODE Transcription Factor Targets 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11328671-jitc-12-4-s003.pdf-452-ZSCAN10_ZSCAN10 Rummagene Transcription Factor Associations 2026 1.0 null Exocarp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.04 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Corpus allatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.063 DAPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43076 Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TWIST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32192 STK11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82039 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95551 SUIT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21126 SW1783 CCLE Cell Line Gene CNV Profiles -1.0 -1.63309 PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-51-ZNF678_ZNF678 Rummagene Transcription Factor Associations 2026 1.0 null SETD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16358 PHF8 ENCODE Transcription Factor Targets 1.0 null NR4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77239 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Palmoplantar keratoderma-esophageal carcinoma syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.631 MRPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39965 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31518 H3K18ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FLCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52863 positive regulation of biological process GO Biological Process Annotations 2015 1.0 null Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.70045 regulation of biological process GO Biological Process Annotations 2015 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09086 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.870491 Bronchopulmonary dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.602 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67564 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of apoptotic signaling pathway GO Biological Process Annotations 2015 1.0 null ARID1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92579 intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00954 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39237 single-organism process GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1299 CCLE Cell Line Gene Expression Profiles 1.0 1.74957 cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.051103 apoplexy; cerebral hemorrhage; cerebral hemorrhages; intracranial hemorrhages; stroke; subarachnoid hemorrhage GAD Gene-Disease Associations 1.0 null EWS-FLI1-20517297-SK-N-MC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EBF1-22473956-BONE-MARROW-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Waist-to-hip ratio adjusted for BMI GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 Dorsal motor nucleus of the vagus nerve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26663 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LPGAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83651 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57125 ES2 CCLE Cell Line Gene Expression Profiles -1.0 -1.50539 larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.471927 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5989213-41467_2018_4462_MOESM9_ESM.xlsx-4-Supplementary_Data_4_Genes_differentially_expressed_in_SETBP1-G870S_vs_Empty_293_FLP-In_lines_whose_promoter_is_occupied_by_SETBP1-G870S_SETBP1 Rummagene Transcription Factor Associations 2026 1.0 null MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.25316 RAB11FIP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32628 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3866 Tuberomammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70787 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null PMC8197658-NIHMS1703954-supplement-Table_S4.xls-Sheet1-Table_S4_List_of_differentially_expressed_genes_near_which_SALL4_CUT_RUN_peaks_were_annotated_related_to_Figure_3_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.5719 NCIH2066 CCLE Cell Line Gene Expression Profiles -1.0 -2.34586 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VAESBJ DepMap CRISPR Gene Dependency 1.0 2.38201 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.973 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-56-ZNF658_ZNF658 Rummagene Transcription Factor Associations 2026 1.0 null ARMC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67096 HDAC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08096 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null MAP3K11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94336 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null NFKBIE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50366 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308612 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZCCHC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47826 BRCA1 ENCODE Transcription Factor Targets 1.0 null C19orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3997 Eb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.95 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 CCNDBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42455 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.853664 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27885 BLTP3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45881 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.26396 heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.879643 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.951285 Thymic medullary epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IFT140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60121 basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067428 CTNNBIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69543 dorsal part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2206 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26353 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42171 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null endometrium HPA Tissue Protein Expression Profiles 1.0 0.737729 Systolic blood pressure GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1 DMTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97516 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KF-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4169-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THUMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46398 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CBX2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null QSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70651 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LMX1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52934 hsa-miR-664 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 ZFPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98728 Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05675 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.3452 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null P300-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.52706 amygdaloid complex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825101 PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTAGE9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42332 BAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95795 intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14642 posterior intralaminar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38892 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-590-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 MEG01 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null Zinc finger, ZZ-type InterPro Predicted Protein Domain Annotations 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null Enterovirus 71_8Hour_None_GSE15323 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.60351 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.45441 CACHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8053 LAMA84 CCLE Cell Line Gene CNV Profiles -1.0 -1.50288 ADAMTS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61723 REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.89982 layer 3 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18139 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13871 posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983915 HCC1419 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-579 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null DTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61969 uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086336 TNFRSF10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8212 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07556 H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PTEN_01_302 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59715 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40135 Zinc finger, RING-type InterPro Predicted Protein Domain Annotations 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4123 496100550_TCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.21881 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ZNF701 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63261 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -2.10021 glutamyl-tRNA(Gln) amidotransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.127 H3K9ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_Fetal Heart Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nb-4 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.889678 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cytotrophoblastic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.601 SETDB1 ChEA Transcription Factor Targets 1.0 null acute myeloid leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.363393 Chorioamnionitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.41 shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75774 HCC1500 CCLE Cell Line Gene CNV Profiles -1.0 -1.34298 MGME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18126 POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Host cellular component COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64935 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FKBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08249 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36261 SOX11_DEPLETION_GDS4801_326_human_Z138 mantle cell lymphoma (MCL) cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Nance-Horan syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.526 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.2998 OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0417 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.763 AR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41344 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26073 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4971 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5590-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JVE015 DepMap CRISPR Gene Dependency 1.0 2.73526 CLPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58088 thyroid GTEx Tissue Gene Expression Profiles -1.0 -0.831841 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC2814 CCLE Cell Line Gene CNV Profiles -1.0 -1.49862 APPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87836 axon part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063378 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RFX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77621 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.824618 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NUAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60304 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null protein modification by small protein conjugation GO Biological Process Annotations 2015 1.0 null SEPTIN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68569 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09086 PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.086 G2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61599 TE4 CCLE Cell Line Gene CNV Profiles 1.0 2.50043 PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF Rummagene Transcription Factor Associations 2026 1.0 null RAB3GAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88741 SP4 ENCODE Transcription Factor Targets 1.0 null POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Insulin Resistance CTD Gene-Disease Associations 1.0 1.20751 H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNUC5 DepMap CRISPR Gene Dependency 1.0 6.71036 zinc ion binding GO Molecular Function Annotations 2015 1.0 null TMX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70805 GSE178907_4_v_3_fkrp_human RummaGEO Gene Perturbation Signatures 1.0 null SLC25A34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84461 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055065 metal ion binding GO Molecular Function Annotations 2015 1.0 null PTGER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70273 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.881076 GSE210655_3_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0377 LN-229 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null