{"symbol":"AATF","synonyms":["CHE-1","BFR2","DED"],"name":"apoptosis antagonizing transcription factor","description":"The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":26574,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26574","proteins":[{"symbol":"AATF_HUMAN","href":"/api/1.0/protein/AATF_HUMAN"}],"hgncRootFamilies":[]}