{"symbol":"ABCA7","synonyms":["ABCX","ABCA-SSN","AD9"],"name":"ATP-binding cassette, sub-family A (ABC1), member 7","description":"The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10347,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10347","proteins":[{"symbol":"ABCA7_HUMAN","href":"/api/1.0/protein/ABCA7_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}