{"symbol":"ABCB8","synonyms":["M-ABC1","EST328128","MABC1"],"name":"ATP-binding cassette, sub-family B (MDR/TAP), member 8","description":"This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":11194,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11194","proteins":[{"symbol":"ABCB8_HUMAN","href":"/api/1.0/protein/ABCB8_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}