{"symbol":"ABCC12","synonyms":["MRP9"],"name":"ATP-binding cassette, sub-family C (CFTR/MRP), member 12","description":"This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":94160,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/94160","proteins":[{"symbol":"MRP9_HUMAN","href":"/api/1.0/protein/MRP9_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}