{"symbol":"ABCC3","synonyms":["ABC31","MRP3","MOAT-D","CMOAT2","EST90757","MLP2"],"name":"ATP-binding cassette, sub-family C (CFTR/MRP), member 3","description":"The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8714,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8714","proteins":[{"symbol":"MRP3_HUMAN","href":"/api/1.0/protein/MRP3_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}