{"symbol":"ABCC4","synonyms":["MRP4","MOATB","MOAT-B"],"name":"ATP-binding cassette, sub-family C (CFTR/MRP), member 4","description":"The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]","ncbiEntrezGeneId":10257,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10257","proteins":[{"symbol":"MRP4_HUMAN","href":"/api/1.0/protein/MRP4_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}