{"symbol":"ABCC6","synonyms":["URG7","GACI2","MLP1","ABC34","MOATE","MRP6","MOAT-E","PXE1","PXE","ARA","EST349056"],"name":"ATP-binding cassette, sub-family C (CFTR/MRP), member 6","description":"The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":368,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/368","proteins":[{"symbol":"MRP6_HUMAN","href":"/api/1.0/protein/MRP6_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}