{"symbol":"ABCC9","synonyms":["CANTU","CMD1O","ABC37","ATFB12"],"name":"ATP-binding cassette, sub-family C (CFTR/MRP), member 9","description":"The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]","ncbiEntrezGeneId":10060,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10060","proteins":[{"symbol":"ABCC9_HUMAN","href":"/api/1.0/protein/ABCC9_HUMAN"}],"hgncRootFamilies":[{"name":"ATP binding cassette transporters (ABC)","href":"/api/1.0/gene_family/ATP+binding+cassette+transporters+%28ABC%29"}]}