{"symbol":"ABI2","synonyms":["SSH3BP2","ABI-2","ABLBP3","ABI2B","ARGBPIA","ARGBP1","ARGBPIB"],"name":"abl-interactor 2","description":"Enables several functions, including SH3 domain binding activity; proline-rich region binding activity; and ubiquitin protein ligase binding activity. Contributes to small GTPase binding activity. Involved in several processes, including Rac protein signal transduction; positive regulation of cellular component organization; and zonula adherens assembly. Acts upstream of or within peptidyl-tyrosine phosphorylation. Located in several cellular components, including actin filament; filopodium tip; and lamellipodium. Part of SCAR complex. Is active in adherens junction. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":10152,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10152","proteins":[{"symbol":"ABI2_HUMAN","href":"/api/1.0/protein/ABI2_HUMAN"}],"hgncRootFamilies":[]}