{"symbol":"ACER3","synonyms":["APHC","PHCA","PLDECO"],"name":"alkaline ceramidase 3","description":"Enables N-acylsphingosine amidohydrolase activity; calcium ion binding activity; and zinc ion binding activity. Involved in several processes, including myelination; positive regulation of cell population proliferation; and sphingolipid metabolic process. Located in Golgi membrane and endoplasmic reticulum membrane. Biomarker of hepatocellular carcinoma and metabolic dysfunction-associated steatohepatitis. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":55331,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55331","proteins":[{"symbol":"ACER3_HUMAN","href":"/api/1.0/protein/ACER3_HUMAN"}],"hgncRootFamilies":[{"name":"Alkaline ceramidases (ACER)","href":"/api/1.0/gene_family/Alkaline+ceramidases+%28ACER%29"}]}