{"symbol":"ACOT11","synonyms":["THEA","STARD14","THEM1","BFIT"],"name":"acyl-CoA thioesterase 11","description":"This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]","ncbiEntrezGeneId":26027,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26027","proteins":[{"symbol":"ACO11_HUMAN","href":"/api/1.0/protein/ACO11_HUMAN"}],"hgncRootFamilies":[{"name":"StAR-related lipid transfer (START) domain containing (STARD)","href":"/api/1.0/gene_family/StAR-related+lipid+transfer+%28START%29+domain+containing+%28STARD%29"},{"name":"Acyl-CoA thioesterases (ACOT)","href":"/api/1.0/gene_family/Acyl-CoA+thioesterases+%28ACOT%29"}]}