{"symbol":"ACOT8","synonyms":["PTE1","HTE","HACTE-III","HNAACTE","PTE-2","PTE2","PTE-1"],"name":"acyl-CoA thioesterase 8","description":"The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. [provided by RefSeq, Oct 2010]","ncbiEntrezGeneId":10005,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10005","proteins":[{"symbol":"ACOT8_HUMAN","href":"/api/1.0/protein/ACOT8_HUMAN"}],"hgncRootFamilies":[{"name":"Acyl-CoA thioesterases (ACOT)","href":"/api/1.0/gene_family/Acyl-CoA+thioesterases+%28ACOT%29"}]}