{"symbol":"ACOX1","synonyms":["SCOX","ACOX","PALMCOX"],"name":"acyl-CoA oxidase 1, palmitoyl","description":"The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":51,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51","proteins":[{"symbol":"ACOX1_HUMAN","href":"/api/1.0/protein/ACOX1_HUMAN"}],"hgncRootFamilies":[]}