{"symbol":"ACSF3","synonyms":[],"name":"acyl-CoA synthetase family member 3","description":"This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":197322,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/197322","proteins":[{"symbol":"ACSF3_HUMAN","href":"/api/1.0/protein/ACSF3_HUMAN"}],"hgncRootFamilies":[{"name":"Acyl-CoA synthetase family (ACS)","href":"/api/1.0/gene_family/Acyl-CoA+synthetase+family+%28ACS%29"}]}