{"symbol":"ACSS2","synonyms":["ACECS","DJ1161H23.1","ACAS2","ACSA"],"name":"acyl-CoA synthetase short-chain family member 2","description":"This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]","ncbiEntrezGeneId":55902,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55902","proteins":[{"symbol":"ACSA_HUMAN","href":"/api/1.0/protein/ACSA_HUMAN"}],"hgncRootFamilies":[{"name":"Acyl-CoA synthetase family (ACS)","href":"/api/1.0/gene_family/Acyl-CoA+synthetase+family+%28ACS%29"}]}