{"symbol":"ADAM19","synonyms":["FKSG34","MADDAM","MLTNB"],"name":"ADAM metallopeptidase domain 19","description":"This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer\u0027s disease. [provided by RefSeq, May 2013]","ncbiEntrezGeneId":8728,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8728","proteins":[{"symbol":"ADA19_HUMAN","href":"/api/1.0/protein/ADA19_HUMAN"}],"hgncRootFamilies":[{"name":"Metzincin metallopeptidases","href":"/api/1.0/gene_family/Metzincin+metallopeptidases"}]}