{"symbol":"ADAM2","synonyms":["FTNB","CRYN1","CRYN2","CT15","PH30","PH30-BETA","PH-30B"],"name":"ADAM metallopeptidase domain 2","description":"This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]","ncbiEntrezGeneId":2515,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2515","proteins":[{"symbol":"ADAM2_HUMAN","href":"/api/1.0/protein/ADAM2_HUMAN"}],"hgncRootFamilies":[{"name":"Metzincin metallopeptidases","href":"/api/1.0/gene_family/Metzincin+metallopeptidases"}]}