{"symbol":"ADAM8","synonyms":["CD156A","CD156","MS2"],"name":"ADAM metallopeptidase domain 8","description":"This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]","ncbiEntrezGeneId":101,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/101","proteins":[{"symbol":"ADAM8_HUMAN","href":"/api/1.0/protein/ADAM8_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Metzincin metallopeptidases","href":"/api/1.0/gene_family/Metzincin+metallopeptidases"}]}