{"symbol":"ADAMTS13","synonyms":["ADAMTS-13","ADAM-TS13","C9ORF8","VWF-CP","VWFCP"],"name":"ADAM metallopeptidase with thrombospondin type 1 motif, 13","description":"This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","ncbiEntrezGeneId":11093,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/11093","proteins":[{"symbol":"ATS13_HUMAN","href":"/api/1.0/protein/ATS13_HUMAN"}],"hgncRootFamilies":[{"name":"Metzincin metallopeptidases","href":"/api/1.0/gene_family/Metzincin+metallopeptidases"}]}