{"symbol":"ADAMTS15","synonyms":[],"name":"ADAM metallopeptidase with thrombospondin type 1 motif, 15","description":"This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which may play a role in versican processing during skeletal muscle development. This gene may function as a tumor suppressor in colorectal and breast cancers. [provided by RefSeq, May 2016]","ncbiEntrezGeneId":170689,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/170689","proteins":[{"symbol":"ATS15_HUMAN","href":"/api/1.0/protein/ATS15_HUMAN"}],"hgncRootFamilies":[{"name":"Metzincin metallopeptidases","href":"/api/1.0/gene_family/Metzincin+metallopeptidases"}]}