{"symbol":"ADGRE2","synonyms":["CD312","VBU","EMR2"],"name":"adhesion G protein-coupled receptor E2","description":"This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]","ncbiEntrezGeneId":30817,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/30817","proteins":[{"symbol":"EMR2_HUMAN","href":"/api/1.0/protein/EMR2_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}