{"symbol":"ADGRE3","synonyms":["EMR3"],"name":"adhesion G protein-coupled receptor E3","description":"This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014]","ncbiEntrezGeneId":84658,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84658","proteins":[{"symbol":"EMR3_HUMAN","href":"/api/1.0/protein/EMR3_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}